Aedes aegypti (Stegomyia) has been human vectors for many human diseases globally. In recent years, dengue virus has been diagnosed in different regions such as Asia and Latin America vectored by Aedes spp. mosquitoes. Dengue cases have been reported again in the several parts of African and other continental hospital. The different types of breeding sites have been found to be abundant in both urban and rural areas. The abundance of adult Ae. aegypti and habitat productivity in different settings escalates the risk of dengue transmission if viruses are found in asymptomatic population. The insecticide resistance has been found to occur in the wild population of Aedes aegypti to insecticides commonly used for indoor residual spray and long-lasting insecticidal net treatments. The control of human vector population is still a challenge as the vector has a diurnal feeding and outdoor resting behavior. Environmental management is still the best practice to be adopted in many countries for Aedes aegypti control. The currently discovered dengue vaccine might be an immediate arsenal for the community immunization.
Part of the book: Dengue Fever
Chikungunya virus (CHIKV) is a mosquito-borneAlphavirus that causes Chikungunya fever (CHIKF) in humans. In 1952, the CHIKV was found in East Africa in a sylvatic and urban cycle between Aedes mosquitoes, and human and nonhuman primates in tropical regions. Since 2004, CHIKF has spread rapidly in Asia, Africa, Europe, and the Americas. Both Aedes aegypti and Aedes albopictus are known to be arboviral mosquito vectors of CHIKV. Ae. aegypti is mostly found within the tropics, whereby Ae. albopictus also occurs in temperate and cold temperate regions. Host-seeking female mosquitoes are infected after feeding on a viremic animal. The replication of CHIKV happens in the midgut and then enters the hemocoel before disseminating to the salivary glands of the mosquito. The disseminated virus can be transmitted by injecting infectious saliva into the host skin during blood feeding. In the naïve host body, CHIKV replicates in the dermal fibroblasts through blood circulation, and disseminates to other parts of the body such as brain cells, kidney, heart, lymphoid tissues, liver, and joints. Symptoms of CHIKV infection include high fever, rigors, headache, photophobia, and maculopapular rash. It is advised to avoid mosquito bites; also, larvae management systems should be applied in endemic environments.
Part of the book: Chikungunya Virus