Akikazu Takada

Hamamatsu University School of Medicine

Akikazu Takada was born in Japan, 1935. After graduation from Keio University School of Medicine and finishing his post-graduate studies, he worked at Roswell Park Memorial Institute NY, USA. He then took a professorship at Hamamatsu University School of Medicine. In thrombosis studies, he found the SK potentiator that enhances plasminogen activation by streptokinase. Using simultaneous analyses of plasma fatty acids, he indicated that plasma levels of trans-fatty acids of old men were far higher in the US than Japanese men. By using simultaneous LC/MS analyses of plasma levels of tryptophan metabolites, he recently found that plasma levels of serotonin, kynurenine, or 5-HIAA were higher in patients of mono- and bipolar depression, which is significantly different from observations reported before. In view of recent reports that plasma tryptophan metabolites are mainly produced by microbiota, he is now working on the relationships between microbiota and depression or autism.

1books edited

5chapters authored

Latest work with IntechOpen by Akikazu Takada

Contributors to this book have reviewed research from the fields of metabolic syndromes in view of their own research. The chapters cover the neural mechanisms of food intake and proposed factors related to obesity. The influences of the intake of sugar and lipids are also discussed. The relationships between cancer and venous thromboembolism in connection with obesity are discussed. Omega (ω) fatty acids and trans-fatty acids are risks of cardiovascular diseases. Comparison of plasma levels of trans-fatty acids indicated that industrially produced trans-fatty acids are higher in American than Japanese men. Hopefully, the book provides information that readers want to obtain in the fields of food intake and metabolic syndromes.

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