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Dil Afroze

Sher-i-Kashmir Institute of Medical Sciences

Dil Afroze (Ph.D) is a Professor and Chair at the Advanced Centre for Human Genetics, Sher-I-Kashmir Institute of Medical Sciences (SKIMS), India. After obtaining her doctorate from Jamia Millia Islamia, India, she joined the Department of Immunology and Molecular Medicine at SKIMS as faculty in 2005. With over two decades teaching experience in immunology and molecular medicine, Professor Dil Afroze is the Vice President of the Indian Immunology Society. She has been a registered guide for basic and clinical graduate and post graduate programs and has mentored postdoctoral fellows as well. She has a number of awards and honors to her credit at the national and international level. She has publications in high impact journals such as Frontiers, the International Journal of Infectious Disease, and the Journal of Chemical Biochemistry and is an editorial board member of several international books (IntechOpen publications). She has been a Visiting Professor in the Division of Oncology, University of Linköping, Sweden and Department of Anatomical Sciences and Neurobiology, University of Louisville School of Medicine, USA.

2books edited

2chapters authored

Latest work with IntechOpen by Dil Afroze

This book offers a comprehensive overview of recent developments in the field of breast cancer biology. It is a complete and descriptive reference on motioning pathways and new treatment options for the future transnational scientists and clinicians working on cancer research and treatment. We greatly appreciate the work of all the contributors to this book. They have brought with them tremendous diversity of perspectives and fields, which is truly reflective of the complexity of the topic, and they have come together in this project to serve as the node of multidisciplinary collaboration in this field. Finally, we must acknowledge the thousands of cancer patients who have participated in the studies, and who have inspired us to gather information to significantly progress knowledge in the field in recent years.

Breast Cancer Biology

Breast Cancer Biology

Edited by Dil Afroze

Books edited

Cancer Survivorship

Cancer Survivorship

Edited by Dil Afroze

Chapters authored

Breast Cancer: Management and Survivorship

By Bilal Rah, Shazia Ali, Mohd Ishaq Dar and Dil Afroze

Breast cancer is one of the most common in female population worldwide and comprises about 22.9% of all cancers. Despite the prognosis and survival rates of breast cancer patients and survivors are comparatively better than other cancers, but their net outcome can be revealed by other factors like tumor grade, secondary effects of chemotherapy like insomnia and health behaviors, this distressing may decrease patient’s life expectancy. In the backdrop of this, the need of the hour for the breast cancer survivors is to assess multifactoral nonpharmacological interventions and the management that includes physical exercise, psychological and complementary medicine, which could be cost effective, widely accessible and more promising for breast cancer patients and survivors apart from pharmacological interventions.

Part of the book: Cancer Survivorship

Cell Cycle and Factors Involved in Inhibition or Progression of Breast Cancer

By Shazia Ali, Mohd Ishaq Dar, Rafiq A. Rather and Dil Afroze

Cell cycle progression is driven by the sequential activation of a family of cyclin-dependent kinases (CDKs), which phosphorylate and activate proteins that execute events critical to cell cycle progression. Cell cycle checkpoints are scrutiny points that display the order, integrity, and fidelity of the major proceedings of the cell cycle. These comprise development to the correct cell size, the replication, integrity of the chromosomes, and their precise separation at mitosis. Many of these mechanisms are prehistoric in origin and highly preserved and hence have been deeply well versed by studies in model organisms such as the yeasts as well as in higher organisms. These molecular mechanisms switch alternative cell fates with substantial impact on tumor suppression. In the present study, we have explained different checkpoint pathways and the consequences of their dysfunction on cell fate in cancer.

Part of the book: Breast Cancer Biology

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