Aditi Singh

Independent scientist

Aditi Singh is a Research Enthusiast, working as an Application Scientist in a Biotechnology company. She has a PhD degree in Molecular-Cell Biology from University of Heidelberg in Germany; and worked as a Post-Doctoral Scholar at University of California San Diego, USA. Aditi has more than 10 years of experience in Molecular and Cell Biology area where she has been involved in various R&D projects and Technical Support. Her Research Interests are RNA Biology, Gene Editing, and Infectious Diseases.

1books edited

1chapters authored

Latest work with IntechOpen by Aditi Singh

RNA interference (RNAi) is a widely used technology for gene silencing and has become a key tool in a myriad of research and lead discoveries. In recent years, the mechanism of RNAi agents has been well investigated, and the technique has been optimized for better effectiveness and safety. On the other hand, the clustered regularly interspaced short palindromic repeats (CRISPR)-associated Cas9/gRNA system is a recent, novel, targeted genome-editing technique derived from the bacterial immune system. Recent advances in gene-editing research and technologies have enabled the CRISPR Cas9 system to become a popular tool for sequence-specific gene editing to correct and modify eukaryotic systems. In this book, we will focus on the mechanisms, applications, regulations (their pros and cons), and various ways in which RNAi-based methods and CRIPSR-Cas9 technology have stimulated the modulation of gene expression, thereby making them a promising therapeutic tool to treat and prevent complex diseases and disorders.

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