The chapter of this book is devoted to characteristics of the ultrastructure and function of secretory cardiac myocytes of the right atrium in norm and the experimental pathology in rats. The data were obtained at various models, such as clinical death, renovascular hypertension in rats, and in the isolated Langendorff-perfused rat hearts. We investigated the effect of the drug Mexidol on morphological and functional characteristics of endocrine cardiac myocytes in rats and in the isolated heart. Quantitative data on intracellular structures of atrial myocytes were presented. We estimated the accumulation of the atrial natriuretic peptide in granules and excretion into the sarcoplasm in secretory cardiac myocytes. The results were obtained using the methods of transmission electron microscopy and immunocytochemistry. The study makes an important contribution to histology and improves the understanding of the function of the heart as an endocrine organ. This chapter is intended for students of medical and biological universities and for experts.
Part of the book: Muscle Cell and Tissue