Paulin Mutwale Kapepula

Curriculum vitae ________________________________________ Personal Informations - MUTWALE KAPEPULA PAULIN - PhD in Biomedical and Pharmaceutical Sciences - Associate Professor : University of Kinshasa, DR Congo - Research center : Centre d’Etudes des Substances Naturelles d’Origine Végétale (CESNOV), Faculty of Pharmaceutical Sciences, BP 212 Kin XII, University of Kinshasa, Democratic Republic of Congo. - Tel: +243 81 051 3448 - E-mail: Garaphmutwal@yahoo.fr Skills areas • Valorisation of phytogenetic resources • Research and intervention on bilateral and non-progressive spastic paralysis of the lower limbs or Konzo in the Democratic Republic of Congo: Evaluation of the antioxidant capacities of traditional foods of Kahemba. • Chemistry of Medicinal Plants (Pharmacognosy) • Bioactivities of Food and Medicinal Plants: Antioxidant and Anti-inflammatory Capacities • Quality control of vegetable drugs, improved traditional medicines, phytomedicines and dietary supplements • Bioactivities of edible insects : caterpillars,… Publications : - Paulin Mutwale Kapepula, D.T.-K., Kapepula, P.M., Dieudonné Mumba, M.F., Désiré Tshala-Katumbay, Dieudonné Mumba, Michel Frédérich, T.M. and, Ngombe, T.M. and N.K., 2018. Traditional Foods as Putative Sources of Antioxidants with Health Beneits in Konzo with, in: Antioxidants in Foods and Its Applications. p. 182. - Muanyishay Lukanda Christophe, Diamuini Ndofunsu Aimé, Mutwale Kapepula Paulin, Ngombe Kabamba Nadège, Bulubulu Freddy, Luhahi Lumba Fatuma, Gédéon Bongo Ngiala, Luyindula Ndiku Sebastien, Pius T Mpiana. 2018. Callogenesis Induction on different types of explants of Tetracera rosiflora Gilg. Journal of Advancement in Medical and Life Sciences, 7 (1), 1-4. - Muanyishay CL, Mutwale Kapepula, D.A., Luhahi, Ngombe Kabamba, L., Mpiana Pius, 2018. Microscopic Features , Chromatographic Fingerprints and Antioxidant Property of Tetracera rosiflora Gilg. Sch. Bull. 402–407. doi:10.21276/sb.2018.4.5.4 - Clément Liyongo Inkoto, Gédéon Ngiala Bongo, Paulin Mutwale Kapepula, Masengo, C.A., Gbolo, B.Z., Ngombe, N.K., Iteku, J.B., 2018. Microscopic features and chromatographic fingerprints of selected congolese medicinal plants : Aframomum alboviolaceum (Ridley) K. Schum, Annona senegalensis Pers. and Mondia whitei (Hook.f.) Skeels. Life Sci. Res. 4, 1–10. - Kapepula, P.M., Ngumbi, P.B., Kawayidiko, M.K., Mpanzu, A.D., Franck, T., Mouithys-mickalad, A., Kabamba, N.N., Tsobo, C.M., 2018. Anti-inflammatory and antioxidant activities of Rungia congoensis , a traditional vegetable consumed by Yombe people from Kongo Central area ( DR . Congo ). Nat. Prod. Res. 6419, 1–5. - Bongo, G., Inkoto, C., Masengo, C., Tshiama, C., Lengbiye, E., Djolu, R., Kapepula, M., Ngombe, K., Mbemba, T., Tshilanda, D., Mpiana, P., Ngbolua, K., 2017. Antisickling , Antioxidant and Antibacterial Activities of Afromomum alboviolaceum (Ridley) K. Schum, Annona senegalensis Pers. and Mondia whitei (Hook. f.) Skeels. Am. J. Lab. Med. 2, 52–59. - Paulin Mutwale Kapepula Lydia Mangala Bahati, , Nadège Ngombe Kabamba, Bénédicte Moni, Gisèle Makengo Kafuti, Patricia Mbombo Mungitshi, Aaron Pambu1, Gedeon Bongo, Adam Tujibikila Mukuta, Jimmy Kabeya Kabengele, Clement Mbadiko Mutunda, Michel Frederich, Théophile Mbemba Fundu. Microscopic Features, Chromatographic Fingerprints and Antioxidant Property of Some Unconventional Green Leafy Vegetables Consumed in Bandundu, DR Congo ; Pharmacognosy Communications, Décembre 2017 - Vawazola Nsimaketo Victor Héritier, Mutwale Kapepula Paulin, Ngombe Kabamba Nadège, Mpuza Kapundu Michel and Masimango Ndyanabo Jude-Thaddée (2017). In vitro antifungal activity of essential oils extracted from some plants of Tangawisi® products on Candida albicans. Journal of Pharmacognosy and Phytochemistry 6(3): 01-05 - Kapepula, P. M., Kabamba Ngombe, N., Tshisekedi Tshibangu, P., Tsumbu, C., Franck, T., Mouithys-Mickalad, A.… Frédérich, M. (2017). Comparison of metabolic profiles and bioactivities of the leaves of three edible Congolese Hibiscus species. Natural Product Research, 6419(March), 1–8. https://doi.org/10.1080/14786419.2017.1305382 - Kapepula, P. M., Mungitshi, P. M., Franck, T., Ngoyi, D. M., Kalenda, P. D. T., Ngombe, N. K.,… Tamfum, J. (2016). Antioxidant potentiality of three herbal teas consumed in Bandundu rural areas of Congo Antioxidant potentiality of three herbal teas consumed in. Natural Product Research, 6419(December), 1–4. https:// - Kabuyi, M. K., Kapepula, P. M., Kabengele, J. K., Moni, B., Makengo, G., Mungitshi, P. M., Fundu, T. M. (2017). Selenium Content and Antioxidant Potential of Some Edible Wild Mushrooms from Bandundu Area, DR Congo. Natural Resources, 8, 103–113. https://doi.org/10.4236/nr.2017.82008 - Tshibangu, P. T., Kapepula, P. M., Kapinga, M. J. K., Tujibikila, A., Kalenda, D. T., Tchinda, A. T., … Jansen, O. (2017). Antiplasmodial activity of Heinsia crinita ( Rubiaceae ) and identi fi cation of new iridoids. Journal of Ethnopharmacology, 196(September 2016), 261–266. https://doi.org/10.1016/j.jep.2016.11.041 - Kapepula, P. M, Tshibangu, P. T.,., Kapinga, M. J. K., Lupona, H. K., Ngombe, N. K., Kalenda, D. T., … Frédérich, M. (2016). Fingerprinting and validation of a LC-DAD method for the analysis of biflavanones in Garcinia kola -based antimalarial improved traditional medicines ଝ. Journal of Pharmaceutical and Biomedical Analysis, 128, 382–390. - Bukatuka, F., Ngombe, K., Mutwale, K., Moni, B., Makengo, K., Pambu, L., … Mbemba, F. (2016). Bioactivity and Nutritional Values of Some Dioscorea Species Traditionally Used as Medicinal Foods in Bandundu, DR Congo. European Journal of Medicinal Plants, 14(1), - Tshilanda, D. D., Mutwale, P. K., Onyamboko, D. V. N., Frederich, M., Ngbolua, K., & Mpiana, P. T. (2016). Chemical Fingerprint and Anti-Sickling Activity of Rosmarinic Acid and Methanolic Extracts from Three Species of Ocimum from DR Congo. Journal of Biosciences and Medicines, 4(January), 59–68. - Nadège Kabamba Ngombe, Patricia Mungitshi Mbombo, Ulrich Maloueki, Désiré Musuyu Muganza, Paulin Mutwale Kapepula, Adam Mukuna Tujibikila, Jean Paul Koto te-Nyiwa Ngbolua, Dibungi T.Kalenda, Antioxidant and antihyperglycemic potential of Isolona hexaloba(Pierre) Englδ Diels(Annonnacea) Leaves : A preliminary Study, International Journal of Medecinal Plants, Photon 105(2013)242-249. Posters : - Paulin Mutwale Kapepula, Arvey Luzayana, Thierry Franck, Théophile Mbemba, Pascal Dibungi T. Kalenda, Ange Mouithys-Mickalad, Nadège Kabamba Ngombe, Didier Serteyn, Michel Frédéric. Microscopic Features, Chemical Fingerprints and Bioactivities of Edible Caterpillars from DR Congo, CIRM Day, 19 December 2018, ULiège, Liège, Belgium - Paulin Mutwale Kapepula, Patricia Mbombo Mungitshi, Jimmy Kabeya Kabengele, Thierry Franck, Ange Mouithys-Mickalad, Dieudonné Mumba, Désiré Tshala-Katumbay, Monique Tits, Michel Frédérich , Nadege Kabamba Ngombe. Chromatographic fingerprintings and inhibitory effect on MPO activity of the leaves of edible Congolese Manihot species. 8th International Conference on Polyphenols and Health (ICPH 2017), 3-6 October 2017, Ottawa, Canada - Paulin Mutwale Kapepula, Thierry Franck, Nadege Kabamba Ngombe, Dieudonné Mumba, Désiré Tshala-Katumbay, Pascal Dibungi T. Kalenda, Monique Tits, Michel Frédérich, Didier Serteyn , Ange Mouithys-Mickalad. Antioxidant properties of tree herbal teas investigated by EPR spectroscopy and chemiluminescence technique. 24th Benelux EPR Meeting 2016, May 20, 2016, Liège, Belgium - P. Mutwale, N. Ngombe, C. Tsumbu , T. Franck, A. Mouithys-Mickalad, D. Mumba,D. Tshala-Katumbay, P. Kalenda, D.Serteyn, M.Tits, M.Frédérich. Chemical fingerprints and biochemical activities of edible congolese hibiscus leaves. 7th International Conference on Polyphenols and Health (ICPH 2015), 27-30 October 2015, Tours, France - Paulin Kapepula Mutwale, Patricia Mungitshi Mbombo, Nadege Kabamba Ngombe, Pascal Dibungi Kalenda, Dieudonné Mumba Ngoyi, Désiré Tshala-Katumbay, Thierry Franck, Ange Mouithys-Mickalad , Jean-Noël Wauters, Monique Tits and Michel Fréderich, Antioxidant and antiradical activities of some vegetables, mushrooms and herb teas of Kahemba: Konzo’s endemic area. 17ème Forum des Sciences Pharmaceutiques, 17 - 18 octobre 2013. - Paulin Kapepula Mutwale, Patricia Mungitshi Mbombo , Kambale Kikandau,Jean Noël Wauters, Fréderich Michel ,Monique Tits, Tamfum Muyembe , Dieudonné Mumba Ngoyi, Désiré Tshala-Katumbay, Pascal Kalenda T.Dibungi and Nadege Kabamba Ngombe, Preliminary Studies Of Nutraceuticals: The Way Forward To Prevent Adverse Health Effects Of A Cassava-Dominated Diet. AFERP & STOLON International Symposium Brussels May 22-24, 2013. Paulin Mutwale Kapepula MPharm. CNOP 0921/02

2chapters authored