Nor'Azim Mohd Yunos
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In the acute medicine, fluid therapy is a common intervention. Clinicians may have different preferences in prescribing the fluids—the type, the volume and rate, and the monitoring of response—but there is a growing argument in the literature for a more consistent and evidence-based approach to these prescriptions. This coincides with the call to treat fluids as drugs and to strategize the fluid management of individual patients. A good start toward observing this call will be an appreciation of the underlying physiology. The hemodynamic, biochemical, and microcirculatory responses to fluid therapy will influence the end-organ and clinical effects. In translating these physiological insights into practice, recent studies in several acute cohorts like trauma, sepsis, and postoperative and intensive care offer valuable guides. With all this in mind, the chapter aims to review the optimal approach to fluid therapy in the acute setting, from the understanding of the relevant basic sciences to the practice at the bedside.
Part of the book: Essentials of Accident and Emergency Medicine