Xianquan Zhan

Shandong First Medical University

Xianquan Zhan received his MD and PhD in Preventive Medicine from West China University of Medical Sciences in 1989–1999. He received his post-doctoral training in Oncology and Cancer Proteomics at Central South University and University of Tennessee Health Science Center (UTHSC). He worked at UTHSC and Cleveland Clinic from 2001 to 2012, and achieved the rank of Associate Professor at UTHSC. Currently, he is a full professor at Central South University and Shandong First Medical University, and an advisor for MS/PhD graduate students and postdoctoral fellows. He is also a fellow of the Royal Society of Medicine, fellow of EPMA, a European EPMA National Representative, full member of the American Society of Clinical Oncology (ASCO), member of the American Association for the Advancement of Science (AAAS), editor-in-chief of International Journal of Chronic Diseases & Therapy, associate editors of EPMA Journal and BMC Medical Genomics, and guest editor of Frontiers in Endocrinology and Mass Spectrometry Reviews. Dr. Zhan has published more than 130 articles, seventeen book chapters, three books, and two US patents in the field of clinical proteomics and biomarkers.

1books edited

7chapters authored

Latest work with IntechOpen by Xianquan Zhan

A proteoform is the basic unit in a proteome, defined as its amino acid sequence + post-translational modifications + spatial conformation + localization + cofactors + binding partners + a function, which is the final functional performer of a gene. Studies on proteoforms offer in-depth insights and can lead to the discovery of reliable biomarkers and therapeutic targets for effective prediction, diagnosis, prognostic assessment, and therapy of disease. This book focuses on the concept, study, and applications of proteoforms. Chapters cover such topics as methodologies for identifying and preparing proteoforms, proteoform pattern alteration in pituitary adenomas, and proteoforms in leukemia.

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