Oral Cancer remains a greatly problematic disease with rising distribution globally, particularly the disappointing presentation among younger age groups. Varying common risk factors exist, including but not limited to premalignant disorders such as human papilloma virus (HPV) infection and immunosuppression. Genetical abnormalities and the field of epigenetics remain a new and vital piece of the puzzle in the development of Oral Cancer. Squamous cell carcinoma (SCC) remains the main histological burden with its varying counterparts; however, many types of other Oral Cancers can present in the mouth and are discussed in this chapter. More so, Oral Cancer brings with it the challenging face of diagnosis and treatment as well as effective control of metastasis. We discuss in this chapter, the epidemiology of the disease, Oral Cancer nomenclature, histological advances, clinical presentations, important risk factors, and metastatic disease pathology.
Part of the book: Histopathology