As a general definition, platelet-rich plasma (PRP) is the concentration of autologous human platelets in a small amount of plasma. PRP contains important growth factors deposited in alpha-granules of platelets and plasma proteins such as fibrin, fibronectin, and vitronectin. PRP has been shown to improve wound healing process in acute trauma wounds, incisional wounds, and chronic nonhealing wounds and is a beneficial agent in reconstructions of soft and hard tissue. Furthermore, PRP enhances differentiation of epithelial cell and collagen bundle organization. Effects of growth factors in PRP on wound healing and successful results obtained with PRP treatment in other types of wound lead to the use of PRP for burn treatment.
Part of the book: Hot Topics in Burn Injuries