Krasimir Kolev is the head of the Hemostasis Division in the Department of Medical Biochemistry at Semmelweis University, Budapest and president of the Hungarian Society on Thrombosis and Hemostasis. He has published more than 50 original papers and 10 book chapters in the field of fibrinolysis. His early interest was in the enzymology of fibrin resolution focusing on mathematical modelling of the process. Recently his team has described the contribution of red blood cells, shear forces, cellular constituents (DNA, histones, myosin, phospholipids) to the modification of fibrin structure and its mechanical and lytic stability. His work has contributed to the current understanding of the impaired fibrinolysis in antiphospholipid syndrome and the role of various proteases in the pathomechanism of stroke.