Muhammad Imran

By Ali Imran, Muhammad Umair Arshad, Sana Mehmood, Rabia Shabir Ahmed, Masood Sadiq Butt, Aftab Ahmed, Muhammad Imran, Muhammad Sajid Arshad, Neelam Faiza, Iahtisham Haq, Shahzad Ali Shahid Chatha, Muhammad Shahbaz, Qasim Ali and Muhammad Waseem

Polyphenols have credentials to tackle the oxidative stress. Oxidative stress is the imbalance between free radicals production and antioxidant enzymes ability to tackle these radicals resulting the onset various metabolic related disorders. Polyphenols based foods have credential as a shield against these glitches mainly owing to their antioxidant potential. In this context, tea polyphenols have gained paramount attention of scientific community as therapeutic agents for the prevention and treatment of various oxidative stress induce maladies owing to their structural diversity, strong antioxidant ability and capacity to modulate various expression involved in the pathogenesis of these maladies. The notable polyphenols are catechins which are mainly present in green tea and further subdivided into various compounds like ECG, EGC, EGCG which has their unique therapeutic potential. The catechins undergo various structural changes and transformed into theaflavins and thearubigins in the process of black tea formation. These are high molecular weight polyphenols and promising candidates in obesity, diabetes and cancer treatment. Mechanistically, these polyphenols ameliorate oxidative stress by trapping the noxious radicals like superoxide and peroxyl, promote the activity of glutathione, suppressing the malondialdehyde (MDA) activity. The current chapter is an attempt to highlight the therapeutic potential of tea polyphenols.

Part of the book: Polyphenols

By Farhan Saeed, Muhammad Imran, Tabussam Tufail and Ali Imran

Part of the book: Malnutrition