Factors that affect the chemical purification process [17].
\r\n\tThere are generally two types of masonry: brick and stone masonry. Brick masonry: a type of masonry that uses bricks. However, masonry is further divided into "clay work," which uses clay to fill various joints with bricks to build walls, and "cement masonry," the cheapest type of masonry. Masonry: this is the art of building with bricks or stone. The ability of masonry to support the load imposed by the structural elements above it is called strength. The application of loads to masonry creates internal stresses and deformations. The brand of mortar and brick, the shape and size of masonry materials, and the thickness and density of mortar joints affect the strength of masonry. The ability of masonry to maintain its position under horizontal load is called stability. This property limits the height of masonry depending on its thickness and the magnitude of wind loads. The thermal conductivity of bricks of different types (silicate, ceramic, facing, refractory) is considered. A comparison of bricks in terms of their thermal conductivity is made; the thermal conductivity coefficients of refractory bricks are presented at different temperatures - from 20 to 1700°C. The thermal conductivity depends mainly on the density and the configuration of the voids. Architecture and construction consist of various elements for building works, and masonry is the main element with which these constructions are realized. Masonry is a piece of fired clay with a rectangular shape and is used to build walls and structures. Nowadays, eco-masonry can be made of different materials that offer a variety of advantages, but all of them offer benefits at the level of the environment and sustainability; some of these utensils are plastic bottles, clay, etc. The book addresses the holistic issue of using modern masonry in construction. This book interprets masonry as an essential theme of contemporary architecture and sustainable construction. It is one of the most valuable materials in the history of mankind.
",isbn:"978-1-83768-126-6",printIsbn:"978-1-83768-125-9",pdfIsbn:"978-1-83768-127-3",doi:null,price:0,priceEur:0,priceUsd:0,slug:null,numberOfPages:0,isOpenForSubmission:!0,isSalesforceBook:!1,isNomenclature:!1,hash:"85ef86d046d15e7d4b1988f1ec5dd750",bookSignature:"Prof. Amjad Almusaed and Prof. Asaad Almssad",publishedDate:null,coverURL:"https://cdn.intechopen.com/books/images_new/12061.jpg",keywords:"Unreinforced Masonry Buildings, Masonry in Sustainable Building, Energy Saving and Masonry, Eco-Friendly Masonry, Modern Architecture and Masonry, Masonry and Human Behavior, Esthetic and Masonry, History of Advanced Masonry, Structural Masonry, Modeling of Masonry Structures, Modern Masonry Manufacturing, Masonry Walls",numberOfDownloads:null,numberOfWosCitations:0,numberOfCrossrefCitations:null,numberOfDimensionsCitations:null,numberOfTotalCitations:null,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"May 20th 2022",dateEndSecondStepPublish:"July 21st 2022",dateEndThirdStepPublish:"September 19th 2022",dateEndFourthStepPublish:"December 8th 2022",dateEndFifthStepPublish:"February 6th 2023",dateConfirmationOfParticipation:null,remainingDaysToSecondStep:"a month",secondStepPassed:!0,areRegistrationsClosed:!1,currentStepOfPublishingProcess:3,editedByType:null,kuFlag:!1,biosketch:"Prof. Amjad Almusaed, affiliated with Jönköping University has carried out a great deal of research and technical survey work and has performed several studies in these areas. 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Due to the detrimental effects of pollution in wastewater, water-related technologies and materials development have become the utmost priority in most of the wastewater industrials [2, 3]. Among the numerous purification methods, integrating coagulation along with filtration [2, 3, 4], sedimentation or flotation [5, 6] have been well-known pre-treatment techniques in water and wastewater settings where water quality is cardinal [7]. However, a variation of inflow water quality and lack of optimized treatment facilities result in decreasing the treatability efficiency with the incurred cost of production [8, 9]. Chemical purification process, well known as coagulation, even though it’s essential in wastewater settings, sometimes is seen to be an expensive technology due to the cause of cost of chemical usage involved [10, 11, 12]. This method involves the precipitation of the soluble metal ions by using coagulants. Subsequently, the long-term application of metal-based coagulants (aluminum and iron) [11] has raised concerns associated with sludge generation and heavy metal residuals which are potentially toxic to the ecosystem [10, 11, 12]. This has resulted in most effluent not complying with the stringent Environmental Protection Agency’s standards for regulating the quality of effluent plants [8].
In a typical wastewater treatment plant (Figure 1), a mixture of inorganic and organic polymer additives are usually employed as a heterocoagulation technique [14, 15]. This is to accelerate the agglomeration and coalescing of weighted particles to be separated from the water either by sedimentation or flotation techniques [5, 6]. However, most of the industrial wastewaters from the oil refinery, food, and the agricultural processing industries contain organics, suspended and emulsified oil and grease that prefer to float than settle [10, 15, 16]. Also, to enhance dewatering and advanced treatment of sewage which includes the removal of phosphorus, the utilization of polymers has become a very common practice [14, 17, 18]. Although, coagulant chemicals and its derivatives are very resourceful in wastewater treatment settings, they may alter the characteristics of the effluents in terms of its physiochemical properties [11, 17]. Also, the problem related to disposal of huge sludge and metals in the effluents, for instance in the application of hydroxide precipitation [4, 13, 19], requires a technique to recover the valuable or toxic metals from the sludge [20, 21]. In response to this, Donnan membrane technology which requires a lower operating pressure than others has been one of the fields tested technique in the wastewater treatment settings. However, the cost of the membrane is one of the setbacks [20, 21, 22].
Schematic flow chart of a typical sewage treatment plant adapted from [
As some of the limitations associated with inorganic based coagulants are been mentioned, this study focuses on the option for the natural and composite inorganic-organic polymer to maximize the treatability performance in the wastewater settings. Therefore, the goal is to evaluate the efficiency of organic polymers as coagulant agents for the treatment of water and wastewater and also to provide an alternative option to metal salts for the chemical purification process. This is done by exploring the use of organic polymer coagulant techniques as compared to metal-based salt coagulants in existing conventional treatment methods on the basis of effectiveness. Furthermore, to identify some of the operating conditions that affect chemical purification process.
Chemical treatment using metal salts of iron and aluminum is widely applied in several wastewater treatment industries as primary treatments for the removal of particulate and organic matter effectively [23]. Figure 2 shows a typical chemical treatment process for both wastewater and drinking water settings, which usually consists of coagulation, flocculation, and sedimentation or flotation [24]. Coagulation is an indispensable mechanism that promotes the aggregation of the suspended solids, which are mostly responsible for turbidity, color, and taste and odor removal [24, 25, 26]. The flocculation facilitates the agglomeration of the coagulated particles to form larger flocs, thereby hastening the gravitational settling or flotation process for the removal of contaminants [24]. The spontaneous forming of flocs in suspension is term as flocculation. This is usually applicable in water purification and sewage treatment. The cationic polyelectrolytes have been the most viable flocculants. Their low charge density makes not to reverse the surface charge and hence they are less prone to induce destabilization.
Physicochemical treatment process [
Also, agglomeration of particles to form large and stable flocs involve mixing of the coagulants with the wastewaters usually monitored via Jar test. However, there are several types of coagulants which show the different potential application in treating drinking water or wastewater [11, 17, 27]. Due to the detrimental effects of discharging untreated wastewater, it is essential for purification systems to be well established and optimized [28, 29]. Ideally, the suitable operation conditions required depends on the characteristics of the wastewater and the coagulants, as well as the physical properties as shown in Table 1.
Coagulant characteristics | MOW characteristics | Physical characteristics |
---|---|---|
Coagulant type | Water quality | Flotation/settling time |
Coagulant dosage | Suspended solids | Mixing intensity |
Coagulant quality | Temperature | Coagulant dosage end point |
Coagulant lifespan | pH | Chemical stability during storage |
Proper solution makeup and dilution | Alkalinity | |
Ionic constituents |
Factors that affect the chemical purification process [17].
Coagulation, flocculation and sedimentation processes in water and wastewater treatment are crucial. The first stage in most chemical water treatment processes is coagulation, whose performance is dependent on coagulant concentration and the water chemistry [12, 14]. Essentially, there are four coagulation mechanisms for aggregation of particles to occur, namely (1) double layer compression; (2) sweep flocculation; (3) adsorption and charge neutralization; and (4) adsorption and interparticle bridging [13, 17, 18, 19, 20, 21, 22, 23, 24]. This involves the reaction between the colloids and the added coagulant to destabilize and neutralize the electric charges in the particles, whereas the flocculation facilitates the agglomerated flocs in the colloidal suspension.
For instance (Figure 3), the addition of the coagulant is accountable for the creation of small scattered particles which come together into larger and more stable particle flocs. These then make the flocs heavier than the water, which settle as sediments and can be removed. This results in the removal of about 90% of the suspended matter [1, 2]. Furthermore, the coagulation step depends on conditions of time and agitation whereby the particles coalesced to form larger flocs could be eliminated by sedimentation.
Process of coagulation, flocculation, and sedimentation [
Conventionally, flotation is a concentration process in which selective hydrophobic materials are separated from hydrophilic materials by a gravity separation process [30]. In a typical flotation process (Figure 4), the coagulated particles adhere to air bubbles lowering the apparent density below that of the water, which then allows the flocs to float to the surface. To cause a change in the separation phase depends on four mechanisms such as (1) air bubble generation, (2) contact between air bubble and the particulates, (3) attachment of gas bubbles to particulates, and (4) rising up of the combined air bubble- particulate [31, 32].
Schematic of coagulation coupled with dissolved flotation process [
The addition of the coagulant enhances the air bubbles and organic matter to form robust flocs that can resist breakage in the flotation zone [33]. However, this process is somehow complicated because it requires the hydrodynamics and surface chemistry interaction via the means of bubble attachment, where the bubbles are generated as a result of compressed air released into the flotation zone. Therefore, to obtain good performance, studies have shown that coagulation chemistry has a strong influence on flotation performance [34], such that the chemical reaction between the coagulants and the organic matter results in forming larger oil flocs, whereas, the flotation process facilitates separation [35, 36]. This allows the coagulated flocs to float on the surface as sludge, whereas clear water moves to the bottom of the floatation tank to the sewer as treated water.
There are several operating factors that have an impact on the parallel and sequential reactions that occur when a coagulant is added to the wastewater. To promote the interparticle bridging and floc formation, there are a series of transportation mechanisms which occurs including Brownian diffusion and fluid motion. All these influence the efficiency and effectiveness of the coagulation process for wastewater treatment.
Polymer molecular weight (MW) and charge density (CD) affects the interparticle bridging and electrostatic force mechanism which contributes to the coagulation efficiency [37, 38], such that an increase in molecular weight improves agglomeration and floc formation. Although anionic charge on the polymer can obstruct adsorption onto an undesirable surface, it promotes the polymer chain via mutual charge repulsion between polymer molecules [39]. Organic polymer concentration originates to be free of molecular weight but reliant on ionic strength. The CD is generally expressed as a percentage of ionic groups (both those that are charged, irrespective of pH and those that can become charged under certain pH conditions) relative to all the groups in the polymer. The CD is expressed in terms of length (qL), area (qA) and volume (qV) as shown in (1)–(3) as a function of the amount of ionic charge (qQ) per length (L), area (A) or volume (V) respectively.
Temperature serves as the driving force for chemical reaction. This affects the coalescence and the physical properties of the polymer including viscosity, mobility, collision, and solubility, density, rising or settling velocity of the flocs. Thus, higher temperature hastens the rate of chemical reactions, whereas low temperatures stabilize the colloidal surfaces to reduce the hydrolysis reactions [38, 40]. This might affect the free movement of the particles and higher solubility as well as higher reaction kinetics of the polymer applied, which in turn decreases the coagulation efficiency.
The degree of coagulation completion for effective treatment can be related to coagulant dosage and mixing conditions. Sequentially, destabilization and agglomeration of coagulated flocs occur through two mixing regimes, viz. rapid mixing and slow mixing as shown in Figure 5. The rapid or fast mixing occurs after the addition of the coagulants, which requires turbulent mixing to form a homogeneous solution [24, 25, 29]. Lack of rapid mixing might cause poor performance of the coagulants due to under dose or overdose. On the other hand, slow mixing comes soon after rapid mixing, and is intended to increase the particle entrapment and growth of the flocs.
Schematic steps of mixing in coagulation process.
Furthermore, consistent slow mixing accelerates the rate floc aggregation and entrapment of the particles in suspension to enhance separation. Slow mixing provides a velocity gradient for particles with similar size that can be larger than 1 μm. Such that the relation between the aggregation of a given size and the polymer MW can enhance the bridging or breaking forces of the flocs to either settle or float [33, 36, 38]. In practice (Figure 5), this is achieved by a suspension being stirred at a high rate (250 rpm f) to cause floc breakage, and after the breakages, the slow mixing (30 rpm) is initiated to increase the floc size [24, 27]. In flotation principle, a lower dosage of the polymer can be used because the agitation creates a well-established suspension of smaller flocs to agglomerate to float [33, 41].
The pH plays a dominant role in coagulant-particle interaction for effective neutralization and agglomeration of the flocs. In addition, the solubility of metal hydroxide species can be affected by pH (4–8) [36, 41]. Therefore pH adjustment prior to coagulant addition is very important to influence the chain reactions that will occur. The effective species of inorganic coagulants or polymers being a metal-based ion can affect the floc formation through a double-layer compression [24, 38]. With an increase in pH, these species become charged resulting in a change in mechanism. For instance, when the colloids are hydrophilic, e.g. acids, the pH will affect the protonation.
There are various types of coagulants used in wastewater settings, such as inorganic and organic polymers. However, polymers are generally more costly than inorganic coagulants. This depends on the type and quantity of chemical the coagulant might contain. Selection of the suitable coagulant for wastewater treatment is very important, which also depends on the water chemistry, the hydrodynamics and operating conditions of the processing system [4, 41]. Coagulant dosage is an energetic factor in finding how the metal ions react with the organic matter in wastewater to enhance its clarity.
Organic polymers by nature are very viscous solutions, which sometimes becomes problematic to be distributed homogeneously in a medium [15, 17]. However, they are very attractive towards particle surfaces, which is irreversible when attached. So uneven distribution of polymers in polluted wastewater might contribute to inefficiency and cost of the treatment process [17, 18, 24]. Thus, the dosage needs to be stepped up in other to compensate for the loss of the polymer.
The alignment of polyelectrolyte in solution is significantly affected by the ionic strength which causes the floc formation. The metal ions hinders the hydrolysis activity when a metal-based coagulant is added to a solution [24, 38, 40]. In contrast, like-charges of a polymer chain tend to expand when there is a mutual repulsion. This is directed to an increase in viscosity of a polyelectrolyte solution as ionic strength decreases. Also, an increase in ionic strength shields the charged site of the polymer which then affects its hydrodynamic volume expansion by decreasing the viscosity of the solution [39, 40]. This causes a double layer compression to be formed around the floc surface area where there might be oppositely charged ions.
There are several types of coagulants which are applicable to water and wastewater treatment settings [42]. These can either be chemical, non-chemical, synthetic material or natural coagulants. However, each type of coagulant has its own unique properties with positive ions which will entrap the negative charge of the organic matter in the water that causes turbidity.
Aluminum and iron salts are the most commonly used inorganic coagulants in the wastewater treatment settings. These include based aluminum metals (aluminum chloride, aluminum sulfate, sodium aluminate) and iron based metals (ferrous sulfate, ferric sulfate, ferric chloride) [13, 17, 18]. The addition of these coagulants to wastewater undergo a series of reactions with the hydroxyl ions (OH−) producing monomeric and polynuclear species. These results in dissociation of their metal salts to release their trivalent ions, which hydrates to give complex water molecules of Al (H2O)63+ and Fe (H2O)63+ for aluminum and iron respectively [26, 37, 39, 43]. This results in the replacement of the water molecules (H2O) by OH− ions to form soluble Al (OH)2+ and Fe (OH)2 which increases the coagulation performance by the trivalent ions being strongly adsorbed onto the negative surface of the colloids [26, 29].
Consequently, metal-based coagulants are most widely used due to their low cost and availability; however, there are some drawbacks [17, 18]. These include high dosage dependence, a high requirement on pH, weakness to temperature disparity and high sludge generation. Some of these inorganic coagulants with their merits and demerits are presented in Table 2. Furthermore, an overdose of aluminum and iron in effluent poses a threat to both the ecosystem and human health such as intestinal constipation, abdomen colic and spasms. In addition, Ferric-based coagulants are very caustic and produce highly visible rust-colored stains associated with chemical spills and leaks [25, 33]. Therefore, there is great interest in improving inorganic coagulants by employing polymeric organic and natural coagulants for the treatment of wastewater.
Name | Advantages | Disadvantages |
---|---|---|
Aluminum sulfate (Alum) Al2 (SO4)3·18H2O | Easy to handle and apply; most commonly used; produces less sludge than lime; most effective between pH 6.5 and 7.5 | Adds dissolved solids (salts) to water; effective over a limited pH range |
Sodium aluminate Na2Al2O4 | Effective in hard waters; small dosage usually needed | Often used with alum; high cost; ineffective in soft waters |
Polyaluminium chloride (PAC) Al13(OH)20(SO)4Cl15 | In some applications, Floc, formed is denser and faster settling than alum | Not commonly used; little full-scale data compared to other aluminum derivatives |
Ferric sulfate Fe2(SO4)3 | Effective between pH 4–6 and 8.8–9.2 | Adds dissolved solids (salts) to water; usually, need to add alkalinity |
Ferric chloride FeCl3.6H2O | Effective between pH 4 and 11 | Adds dissolved solids (salts) to water; consumes twice as much alkalinity as alum |
Ferrous sulfate FeSO4·7H2O | Not as pH sensitive as lime | Adds dissolved solids (salts) to water; usually need to add alkalinity |
Lime Ca(OH)2 | Commonly used; very effective; may not add salts to effluent | pH-dependent; produces large quantities of sludge; overdose can result in poor effluent quality |
Organic coagulants are generally synthesized monomers of aluminum and iron-based coagulants, applicable in the wastewater settings as coagulant aids or floc builders [15, 17]. Table 3 shows some of the organic coagulants which are usually employed in potable and wastewater treatment after the addition of inorganic coagulants to enhance its treatment efficiency [15]. There are various types of organic coagulants, which have different covalent charges and bonds of their polymeric molecules. These include the charge or ionic polymers (polyelectrolytes) and no charge or non-ionic polymers [15, 25]. In respect to the charge polymers, those with a positive charge are termed as cationic polymers, whereas those with negative charges are called anionic polymers.
Name | Formula | Typical properties | Uses |
---|---|---|---|
Polyaluminium chlorohydrate (ACH) Al2(OH)5Cl | PAC 23 | * 23–24% Al2O3 or 40–41% w/w ACH | Used in lieu of alum where raw water has low pH & alkalinity. Has little impact on pH |
MEGAPAC 23 | |||
ALCHLOR AC | * SG 1.33 | ||
* 83–84% basicity | |||
PROFLOC A23 | * 8.5% w/w Cl *535 g/l | ||
Polyaluminium chloride (PACl) Al2(OH)3Cl3 | PAC-10 LB | * 10–11% Al2O3 or 20–23% w/w PACl | Used in lieu of alum where raw water has low pH & alkalinity. Has greater impact on pH than ACH |
MEGAPAC 10 | |||
* SG 1.18 | |||
* 50% basicity | |||
* 10.5% w/w Cl | |||
* 245 g/l | |||
Polyaluminium silicosulphate Al2(OH)3.24Si0.1(SO4)1.58 | PASS® | * 10% Al2O3 or 5.3% w/w Al | Forms flocs easily |
* SG 1.34 | |||
* 54% basicity | |||
Polyferric sulfate Fe2(OH)0.6(SO4)2.7 | PFS® | * 12.2% w/w Fe(III) or 43.7% w/w Fe2(SO4)3 | Mostly used for oil emulsified wastewater |
* SG 1.54 | |||
* 10% basicity | |||
* 673 g/l |
There are two characteristics of polymers that defines them to be used as coagulant or flocculant aids [15, 17]. These include (1) they have a very high charge density to neutralize the negative charges present on the surface of the colloidal material, and (2) they have a relatively low molecular weight (MW) which allows good diffusion of the cationic charges around the particles. This enhances good distribution of the coagulant in the effluent, when not concentrated at low viscosity of less than 2 × 103 centipoises, and when concentrated at a high viscosity of 20 × 103 centipoises [14, 15, 24]. Organic polymers have long chain molecular weights, which consists of repeating chemical units called monomers. This makes them be classified as low with MW less than 105, and medium and high when they are between 105 and 106 and more than 106 respectively [14, 15, 17].
Organic polymer coagulants can exist in different forms which is due to the method of polymerization such as liquid, beads, powder, emulsion, and dispersion [15, 24].
Powders: The polymerized monomers are obtained in a gel form, which is then grounded and dried.
Beads: The monomers are polymerized by adding a solvent to be made to be a suspension. The solvent is later evaporated to obtain microspheres. This prevents dust and enhances rapid dissolution.
Emulsions: The monomers are emulsified in a solvent before being polymerized. Afterwards, a surfactant is added to make it dissolvable in water.
Liquids: The monomers are polymerized at low concentration in aqueous solutions, making it effortlessness to use.
Dispersions: In this case, the monomers are usually dispersed in brine before being polymerized. This is done as direct feed inline without any solvent or surfactant and aging time. These are applicable in the flotation process, making it a cost-effective process for the treatment of oil refinery wastewater. Figure 6 shows the dissociation of the ionic charge of the polymer when introduced into a receiving medium (emulsion of oil-water).
Schematic coagulation process of oil-water emulsion using an organic polymer [
Hydrophobic organic coagulants adapted from inorganic coagulants have gained attention in application due to their unique characteristics. Organic polymers, in general, are classified as natural and synthetic polymers [14, 15, 17]. Natural polymers are hydrophilic compounds which carry natural characteristics as being nontoxic to humans, readily available and environmentally friendly. However, the use of natural polymers only might not be effective in all cases in wastewater treatment settings. This might be due to their properties which cannot be modified (e.g. Chitosan, tannin, starch,
Organic polymers can easily be modified and optimized during the manufacturing process for wider application. Several polymers are produced with polymer chains of the linear, branched or cross-linked form of structures [11, 18]. For instance, Figure 7 shows the chemical structure of poly diallyl dimethyl ammonium chloride (pDADMAC), epichlorohydrin/dimethylamine polymers (ECH/DMA) and cationic polyacrylamides (CPAMs) are examples of cationic synthetic polymers while chitosan is an example of the cationic natural polymer [15, 17, 24].
Common structures of cationic (PDADMAC, ECH/DMA, CPAM) and anionic (APAM) synthetic polymers and natural polymer chitosan [
Anionic polymers are amphoteric polymers, which gets a negative charge when their ionic groups dissociate in a medium [15, 17]. Their polymerization is very sensitive, involving a change in molecular weight, charge groups and density as well their structure being linear or branched as shown in Figure 8. This is usually instigated by using either active anionic species like sodium, nitrile, hydroxide or cationic species such as hydrochloric acid, sulfuric acid, and phosphoric acid. Subsequent hydrolysis of the polyacrylamide under basic pH conditions produces a polymer with anionic charges. Table 4 shows the molecular formulas of anionic APAMs or PAMs, containing changing proportions of acrylamide co-monomers in terms of charge density (mol%) and a theoretical basis in meq/g of polymer.
Copolymers of acrylamide and acrylic acid to form anionic polyacrylamides [
Molecular formula | CD (mol %) | CD (meq/g) |
---|---|---|
C3H3 O2Na | 100 | 10.2 |
(C3H3 O2Na)0.75(C3H5 ON)0.25 | 75 | 8.5 |
(C3H3 O2Na)0.50(C3H5 ON)0.50 | 50 | 6.1 |
(C3H3 O2Na)0.25(C3H5 ON)0.75 | 25 | 3.3 |
(C3H3 O2Na)0.1(C3H5 ON)0.9 | 10 | 1.4 |
Charge densities of anionic polyacrylamides [17].
Cationic polymers are positively charged natural or synthetic based organic coagulants. Some of these polymers have charge ammonium groups making them strong electrolytes irrespective of their pH variation [15, 17]. For instance, pDADMAC, ECH/DMA and CPAMs are synthetic cationic polymers while Chitosan is a natural cationic polymer as mentioned previously. The hydrolysis of the ester groups and consequent loss of cationic charge is CD and pH dependent. Table 5 outlines the CD of various cationic polymers in mol% and meq/g of polymer. The higher charge density shows that the polymer has a greater loop which enhances interparticle bridging and effective destabilization of the medium. Figure 9 shows the cationic polymer structure, denoting polymerization of acrylamide followed by partial hydrolysis.
Polymer | Molecular formula | CD (mol %) | CD (meq/g) |
---|---|---|---|
PDADMAC | C8H16NCl | 100 | 6.2 |
ECH/DMA | C5H12 ONCl | 100 | 7.3 |
CPAM | C8H16 O2NCl | 100 | 5.2 |
CPAM | (C8H16 O2NCl)0.5(C3H5 ON)0.5 | 50 | 3.8 |
CPAM | (C8H16 O2NCl)0.25(C3H5 ON)0.75 | 25 | 2.5 |
CPAM | (C8H16 O2NCl)0.1(C3H5 ON)0.9 | 10 | 1.2 |
Chitosan | C6H11 O4N.HCl | 100 | 5.2 |
Charge densities of cationic polyelectrolytes [17].
Copolymers of acrylamide and a chloro-methylated monomer to form cationic polyacrylamides [
There are several naturally-occurring polymers that have inherent cationic properties, which can be modified to yield a cationic polyelectrolyte to be used for solid-liquid separations as flocculants [11]. Non-ionic polymers vary in structure, molecular weight and degradability. Some examples include polyacrylamides (PAMs), Chitosan, starch without substitutions, cellulose derivative, and glues [17, 38, 44]. Chitosan, like most natural polymers, is toxic free which makes them generally acceptable on health grounds. The use of chitosan in water purification applications has been referenced to decolorizing dye house effluents, the treatment of food-processing wastes, metal ion removal and sludge conditioning.
Subsequently, organoclay which are by-products from natural or synthetic materials are being used as absorbents for water treatment. They are generally known as low-cost adsorbents which are readily available. These include ball clay, bentonite and kaolin. Organoclay is also a result of merging sodium montmorillonite clay with a cationic quaternary amine salt which interchanges the adsorbed sodium through ion exchange [17, 25].
Furthermore, plants and minerals are a cardinal source of natural polymers. Some examples includes:
Organic polymers and inorganic coagulants over the years have been used in chemical treatment and purification of water and wastewater [41]. These are used in chemical treatment to assist sedimentation of sewage solids to enhance the removal of suspended matter. Coagulation used ahead of gravity settling may be expected to yield suspended solid removals of about 90% as compared to without coagulation [1, 11]. This concept is also applicable to primary coagulation of industrial wastewaters where the separation may be based on flotation, as in examples from the leather, steel, wool scouring, cosmetic, detergent, plastics, dyehouse, paper, food processing, and brewing industries. The cationic polymer which is hydrophobically modified is significant in the case of soap, oil and grease removal. Table 6 shows some examples for the application of organic polymers for the treatment of wastewater.
Industries | Coagulant | Dosing | Performance | Reference |
---|---|---|---|---|
Pulp and paper | Poly-aluminum-silicate-chloride | 40 mg/l | 93.13% COD 91.12% turbidity | [45] |
Textile industry | PAC | 25 mg/l | 90.17% COD, 74.09% TDS and 93.47% turbidity | [37] |
Dye wastewater | Polyferric chlorides (PFCs) | 30 mg/l | 55% reduction | [46] |
Vegetable tannery wastewater | PACl (poly aluminum chloride) | 60 mg/l | 45%TSS, 20% COD and 80% turbidity | [47] |
Palm oil effluent | PAC | 0.5 g/l, 8.0 and 60 g/l | 99% SOG | [48] |
Application of organic polymers in wastewater settings.
Their many advantages associated with organic polymers been used as primary coagulants, however, it is sometimes quite challenging selecting the suitable one for specific water treatment. The selection of the right polymer to use under the circumstances in question depends on their molecular weight, charge density, and structure, dose, mixing condition, amount and type of impurities found in the water and pH dependency. However, to achieve optimum stabilization and agglomerating of flocs requires optimum dosage, which is inversely dependent on the size of the particles in suspension [39, 40].
Coagulation is one of the simplest methods for the treatment of water and wastewater, especially for non-settleable solids, turbidity, and color from effluents. Application of coagulation is expected to enhance the gravity system for the removal of suspended solids of about 90% as compared to a system without coagulation. Thus, the issue of sludge sedimentation which must be floated is relatively low to flotation systems utilizing organic polymers rather than inorganic coagulants. This chapter addresses the limitation associated with coagulation using inorganic coagulants, by highlighting some of the eco-friendly organic coagulants and operating parameters of coagulation for water and wastewater treatment. Also, composite polymerization and impregnation of organic polymers with inorganic coagulants as a research area should be focused for commercialization and industrialization.
The authors wish to thank the Durban University of Technology and National Research Foundation South Africa for their support.
Climate change has been recognized as one of the most serious environmental, social, and economic challenges facing the world today. Several studies in Portugal and Spain recognize the tendencies for climate change at regional level [1, 2, 3, 4, 5, 6].
In Alentejo Central, the Intermunicipal Plan for Climate Change Adaptation (PIAAC-AC) [1] has already identified the tendencies and future scenarios of climate change in Alentejo Central until the end of the XXI century, namely the increase in the number of days with very high temperatures, the number of tropical nights and heat waves, and the general decrease in annual rainfall. In this scenario, the concerns with school communities and users of social action services increase.
The project “LIFE-myBUILDINGisGREEN”—“application of nature-based solutions for local adaptation of educational and social buildings to climate change,” developed by CIMAC in partnership with the CARTIF Technology Center (Spain), Diputación de Badajoz, the CSIC—Consejo Superior de Investigaciones Cientificas (Real Jardin Botanico—Spain), and the Porto City Council, focuses on the construction sector, in particular on education and social services buildings in all cities and towns in Europe. It aims the implementation of 3 prototypes (building adaptation) of nature-based solutions (NBS) on walls, roofs, exterior surfaces, and car parking of 3 pilot buildings, one located in Évora—Alentejo Central—South of Portugal, one in the city of Porto in the north of Portugal and one in Solana de los Barros in the Badajoz Province—southwest of Spain. The overall objective is to contribute to improve the resilience in these buildings using NBS and autochthone vegetation. This paper presents the LIFE-MyBuildingisGreen project, its objectives, and expected results [7].
Climate change is now recognized as one of the most serious environmental, social, and economic challenges facing the world. The IPCC’s Fifth Report (2014) [8] identifies that many of the global risks of climate change are concentrated in urban areas. In addition, implementing measures that enhance resilience and enable sustainable development can accelerate processes of adaptation to climate change [9].
Europe’s educational and social service buildings will face multiple challenges in the coming decades, and climate change will add pressure to it. The project focuses on the building sector, specifically on the public buildings dedicated to education and social services existing in all cities and towns in Europe. The impacts of climate change (heat waves and changes in annual and seasonal precipitation patterns) are affecting the health and well-being of children and elderly people who are the main users of these types of buildings [10, 11, 12].
The overall objective of the project is to contribute to increasing the resilience of these buildings by implementing in them NBS as prototypes of climate adaptation and improved well-being. Additionally, other specific objectives are:
Improve knowledge base on the development, assessment, and monitoring of vulnerability to climate change of buildings through developing and testing a common, ready-to-use method in the southern, western, central, and northern European regions.
Analyze and verify the impact of NBS as adaptation measures to climate change in three pilot buildings.
Promote sustainable ecosystem-based adaptation measures and increase the capacity to apply such knowledge in practice through dissemination and demonstration workshops.
Promote the governance of regional authorities, directors and building managers, and the building industry to integrate NBS as part of measures to promote sustainable adaptation in buildings through the development, creation, and dissemination of governance tools and territorial agreements.
Contribute to the development and implementation of a common policy at the UE level on adaptation and climate change by transferring best practices and knowledge base to target groups and stakeholders.
The main actions of the project are:
Selection of 3 pilot buildings by weighting the technical criteria that characterize each building. Analysis of European databases with information relevant to the implementation of NBS in public buildings of education and social services.
Evaluation and analysis of the baseline of each building to determine the initial state of the building and to use it as a reference to assess the impact of the NBS using the indicators proposed within the Project.
Installation and implementation of 3 prototypes based on nature in facades and partition walls, roofs, and exterior surfaces of each selected pilot building. In addition, it will be complemented by the implementation of sustainable measures of induced natural ventilation, seasonal shading (natural and artificial), and the choice of native Mediterranean and Atlantic species.
Monitoring of the impact of the works carried out with the aim of verifying and evaluating the importance of these measures as alternative solutions to climate adaptation for regional authorities at the local level.
Creation of actions and tools of governance that make possible the signing of government agreements, the development of inter-municipal programs, and the integration of the NBS into regulations and multi-year action plans of political, technical, and institutional scope.
Demonstrating the feasibility and transferability of NBS as measures for sustainable adaptation to stakeholders in policy, building, climate change, building, and urban planning at local, national, and European levels. Creation of capacities to improve knowledge about the NBS to the responsible authorities and users, directors, and managers of education and social services centers and the building sector.
Communication and dissemination of the results and good practices of the Project through the website, bulletin board, newsletters, brochures, press articles, and networking at regional, national, and European levels and dissemination activities online with all interest groups and stakeholders.
In the case of Portugal and specifically in Alentejo and Oporto (areas of action of the Project in Portugal), the residential park in 2011 was around 111,826 accommodations. There are more than 120 public buildings of responsibility and municipal management that serve around 238,000 people. Of these, 49 correspond to public elementary schools and the others refer to administrative, institutional, cultural, and sports buildings, scattered throughout Alentejo and Oporto. These buildings house more than 3000 employees. In Portugal, it is the state that assumes the ownership of the buildings of education and social services, but the management and maintenance are carried out in a shared way between the state and the municipalities. The vulnerability to climate change of these buildings, located in regions and municipalities of Spain and Portugal, is a consequence of the high temperatures that are reached inside them between the months of May to October and the constructive characteristics of these buildings [13].
Part of the heating problem of these buildings can be attributed to the construction typology and the materials used. In Spain and Portugal, many of the education and social services centers were built prior to the basic thermal conditions’ regulation (Royal Decree 2429/79, of July 6, which approves the Basic Building Standard NBE- CT-79, on Thermal Conditions in buildings). This document provided the basic design criteria that allowed damping of the thermal wave through the enclosures. It was from that moment when thermal insulation incorporated into double-leaf walls began to be used, achieving a notable improvement in the thermal performance of the facades with respect to the mass walls used in previous years. This regulation was replaced by the current Technical Building Code, in 2006, in which special attention has been given to reducing energy demand with the incorporation of high-performance solutions in the enclosures.
As a result, we find insufficiently thermally insulated buildings, and with little sun protection in window openings, which in hot climates such as those in Spain or Portugal, produces overheating effects in last spring, summer, and early autumn periods [14].
In addition, regulatory and labor regulations establish that the temperature inside these buildings should not be less than 10°C or higher than 27° since it allows risk due to thermal stress and causes health problems for the workers. The company or public authority responsible must take the necessary preventive measures and the work and teaching activity should be paralyzed if the thermal risk is maintained.
In this regard, it is worth mentioning that there is currently a significant climate problem and social impact in the regions of Southern Europe, specifically in Spain and Portugal.
This problem is related to the high temperatures inside education and social services centers that users suffer regularly between May and October, with the decrease in environmental comfort in these buildings and with the worsening conditions of health and well-being of the users. So much so that the aforementioned climate problem is addressed by the digital and written press of countries such as Spain, Portugal, Italy, and France that echo on the front pages of this pressing situation in educational and social centers.
The solution to this problem cannot go through the application of a Climate Control Program that allows the installation of artificial cooling by means of air conditioners in these public centers, since neither the responsible public authorities nor the European guidelines advise it, because they contribute to global warming, due to its high consumption of electrical energy and emission of CO2 into the atmosphere [15]. In addition, air conditioners have contributed to increasing the percentage of citizens with respiratory problems such as laryngitis or pharyngitis and have exacerbated the chronic processes of the population at risk. To date, the solutions that the administrations responsible for these centers are taking are the regularization of the students teaching hours, allowing parents to take their children ahead of time as a result of the maximum peaks of indoor temperature coinciding with the hours Central of the day. This situation is causing disorganization of schedules that makes it more difficult to reconcile work and family life [11].
In the sense of the framework of a local adaptation strategy against the effects of climate change in these buildings, it must generate governance tools between the different regional and local administrations with responsibilities in the field of education and social welfare, which allows these centers to innovate and rehabilitate by implementing nature-based solutions that allow to respond to periods of potential overheating and minimize unwanted heat gains during the day and night. The application of these NBS tools in public education and social services centers will enable responsible local administrations to fulfill the objective of the Covenant of Mayors for climate and energy, as well as offer natural, and sustainable response related to the environmental comfort and temperature inside these buildings.
Alentejo’s central climate is typical Mediterranean. It is a mesothermal climate type with rainy winter and hot, dry summer. However, the geographical position of the Alentejo Central and the layout of the main relief masses of southern Portugal give its (Mediterranean) climate a certain continental character [1].
In general, Alentejo Central has an air temperature regime, with average annual temperature values around 16°C, with a relatively high annual temperature range in the national context, which is accentuated inland. Winter is cool, with average temperatures slightly below 10°C and average minimum temperatures around 5°C, with January being the coldest month.
The summer in the Alentejo Central is hot or very hot, with the heat conditions inland, as well as in the most sheltered and/or less ventilated places. In this context, average temperatures in the warmer months (July and August) range from 23 to 25°C, with average maximum temperature values exceeding 30°C.
The most significant trends observed from 1971 until 2015 were an increase in the mean annual temperature, with a greater incidence in spring and summer maximums, with a greater frequency of tropical nights. In addition, there has been a reduction in precipitation in summer and autumn and an increase, in this last season, in precipitation events concentrated in short periods.
In general, the climate of Badajoz can be described as the Mediterranean with slight Atlantic-continental nuances. Temperatures are very high in summer and mild in winter, with a substantial incidence of sunlight and long hours of sunshine, with the maximum values in the westernmost part, near Portugal. An essential thermal amplitude stands out, evidencing the marked seasonality typical of the Mediterranean climate. Precipitation is the primary source of humidity for the region. Although the general precipitation balance is negative from all points of view since it is scarce in most of the territory, there is also significant evaporation due to the high temperatures, making these rains even more insufficient [16].
As far as rainfall behavior throughout the year is concerned, in Badajoz, there is an evident dry season, summer. There is rainfall in the rest of the year, although with greater abundance toward the end of autumn and beginning of winter, with less critical rains in the rest of autumn and during spring.
In recent decades in the territory of Badajoz, there has been a tendency to increase the minimum temperature while spring precipitation decreases and autumn precipitation increases. An increase in the number of hot days is occurring, as is a decrease in the number of cold days.
The city of Porto is part of the NW of the Iberian Peninsula, in the coastal strip of the Atlantic Ocean, suffering the influence of the sea currents that dominate the North Atlantic, which find in this area of the Iberian Peninsula the first contact with a continental area. Despite belonging to the Atlantic climatic subtype, the climate in Porto has particular characteristics as a result of the influence and attributes, and positioning of an important barometric apparatus—the Anticyclone of the Azores.
In the last 40 years, there has been a steady pace characterized by a moderately cool winter in the areas closest to the sea and cold or very cold in the most sheltered areas of the interior and at the highest altitudes, a moderately warm summer often influenced by the winds of NW and the morning advection fogs along the coast, and hot or very hot in areas far from the Atlantic moderating action or higher altitude [6]. Precipitation is more frequent and intense in the winter months but can occur throughout the year. Winters in O’Porto have tended to be moderately cool along the coast and cold to very cold inland. While the summers have been moderately warm by the sea, they become hot inland. Precipitation tends to be concentrated toward the end of autumn and the beginning of winter.
Climate scenarios are made through the collection and treatment of future climate information (projections) using different models and for different global climate scenarios, serving as support to identify possible changes in future climate.
As a result of the global problem of climate change, both in Portugal and Spain, studies have been developed to analyze the scenarios that could occur in the future [1, 2, 3, 4, 5]. In the different scenarios, the most extreme weather conditions will be reinforced, generating critical variations in the meteorological variables. Temperatures will suffer a general increase in the annual average in the areas studied. Very hot days will increase in summer, autumn, and spring. Rainfall will suffer a decrease, accompanied by shifts in its distribution between the different seasons, with an increase in autumn.
Due to these scenarios and the actual conditions of the educational buildings referred in the introduction, the partnership of the project “MybuildingisGreen” [7] decided to study and implement in each one of the selected buildings the solutions as explained in the next section for the Évora pilot building.
In an increasingly urbanized world, nature—rich in intelligent and efficient solutions to the challenges of cities—has been forgotten in the design and management of urban spaces. Many of the green (vegetation) and blue (water) surfaces have been transformed over time into gray (impermeable) surfaces, with serious implications for the quality of life of the inhabitants and increasing environmental risks.
Currently, some of this natural engineering has been trying to rescue some of this natural engineering for cities in order to ensure sustainable, cost-effective, multifunctional, and flexible solutions to various environmental challenges. This movement recognizes that it is more advantageous—ecologically and economically—to work alongside nature and nature than against it.
The European Union developed the EU Research and Innovation policy agenda on Nature-Based Solutions and Re-Naturing Cities [17, 18], which aims to position the EU as a leader in “Innovating with nature” for more sustainable and resilient societies. The EU defines nature-based solutions “as solutions that are inspired and supported by nature, which are cost-effective, simultaneously provide environmental, social, and economic benefits and help build resilience. Such solutions bring more and more diverse nature and natural features and processes into cities, landscapes, and seascapes, through locally adapted resource-efficient and systemic interventions.”
The project My Building is Green aims to strengthen and support cities, and EU within the shift of the old urban paradigm based on gray surfaces, and works to contribute with specific and innovative nature-based solutions (more efficient, more sustainable, and greener) to the adaptation of buildings and improve the bioclimatic comfort and quality of life of users [12, 13, 14], which also act (each school), for example, as inspiration and a starting point for shift and adapt to climate change in cities.
Hereafter, some innovative solutions developed and projected within the project will be presented. However, it has to be mentioned that there are multiple NBSs that can be applicated for the adaptation of buildings to climate change, according to the type of construction to the climate and the vulnerability expected [7].
This system was created by the CARTIF Team in collaboration with SingularGreen and consists of a multilayer tray to maintain cover vegetation that is encapsulated with a white waterproof sheet to collect rainwater and reduce water loss [7]. The design of the system, including the selection of the appropriate plant species, is done so as not to require the installation of auxiliary irrigation. In the upper part of the encapsulation, there are some holes for planting plant species.
Schematically, the system would be a system of extensive vegetative cover pocketed to make it more resistant to rainfall shortages (Figure 1).
Prototype mBiGWTray: Schema and implementation.
This system allows the installation of the trays on the roof directly occupying 50% of the surface with the vegetal part initially and the rest with a white surface that avoids the excessive capture of thermal energy. The installation is carried out using a checked system in which the planting surfaces alternate with the water collection surfaces.
In the joining area of each module, there are some holes that allow the entrance of water from the zone of collected water toward the zone with the vegetal system.
The bags have a drainage hole at the surface of the tray to allow the greatest amount of water to be stored avoiding the pooling of the substrate in which the roots of the plants are found.
Both the weight of the tray itself and its flat design mean that, in principle, an auxiliary roof anchor system is not necessary. However, if the prevailing winds in the area were very strong, the system could be weighed down using draining aggregate as partial filling of the holes in the tray.
The components of the System are:
The encapsulation material can be made of white EPDM or PVC in order to get adequate durability. In principle, white PVC is selected as the first option by price mainly. The durability of the two materials is similar for this application, both with a 10-year warranty.
The tray is composed of support with cavities to contain the planting substrate of the plants to be included. This is a MODI H50 ventilated pavement plate that is covered with a non-woven felt geotextile and inserted into the capsule. This tray allows structuring the planting of the vegetation, providing rigidity for handling the bagging, and creating spaces for water storage inside.
Between the tray and the geotextile is the material that acts as a substrate that can be both sheep’s wool and sphagnum or other similar materials. This layer allows transport by capillarity from the water storage area to the upper zone.
Above the geotextile is a layer of substrate encapsulated in a light geotextile. In this area, it is where it contains the root part of the vegetation that is integrated into the system.
The characteristics of the selected species are underwater requirement, creeping and surface roots, native species, and species indicated as beneficial for pollinators. A plantation of 16 plants per tray would be carried out. Initially, there would be bands covered with vegetation and bands without vegetation but over the years one could have a complete green cover.
On the other hand, the system is compatible with drip irrigation that can be integrated into the base structure. A more homogeneous vegetation maintenance would be achieved throughout the year. However, the initial design has been carried out so that the implementation of an irrigation system is not necessary and the previous tests that are going to be carried out are aimed in this direction.
This system has been designed to create vertical surfaces with vegetation of very low thickness to create shading with a contribution of humidity to the environment. The system consists of an impermeable sheet on which a nonwoven felt is adhered and a semi-woven substrate is projected. Due to the low substrate thickness, hydroponic irrigation is integrated that is distributed by gravity across the surface of the substrate (Figure 2). In the lower zone, a channel for collecting excess irrigation is integrated and returned to the irrigation station.
mBiGToldo schema and implementation.
Irrigation is done through a hydroponic irrigation station with adequate programming to cover the needs of the vertical garden at all times of the year and the environmental conditions that are to be generated. It is necessary to connect the irrigation station, to be installed under the level of the mBiGToldo, with all the gardens, both to provide the irrigation and to collect [7].
The components of the System are:
Support frame: Structure with the appropriate dimensions made with the material with which the vertical wall structure that will support the prototypes of the facade is built.
Waterproof support. It must be a sheet-shaped material resistant to punching and tearing to facilitate fixing. The currently recommended material is a PVC awning sheet but more sustainable materials are being sought.
Root fixing sheet based on nonwoven felt or rock wool.
Mix of substrate and compatible seeds that is applied by projection.
The characteristics of the selected species will be easily propagated by seeds.
Drip irrigation tube in the upper part and water collection gutter and injected to leftover water collection tube.
The system is only compatible with hydroponic drip irrigation that can be integrated into the support structure of the awning. The design includes a system for collecting excess irrigation water and returning it to the tank for optimization of water consumption.
Among the species that can be used are the
The mBi_GUL is a prototype solution inspired by Green Urban Living System (GUL), an innovative option develop under the Green Urban Living project (greenURBANLIVING), promoted by Amorim Isolamentos, Itecons, Neoturf, and ANQIP, and financed by European Commission through European Regional Development Fund. The Green Urban Living (GUL) is a multifunctional system based on expanded cork agglomerate for the construction of green roofs and living façades (Figure 3).
Prototype layer scheme based on the GUL system (left). Example of an installation using the GUL system. Source: Neoturf (right).
This system was developed within a national project, which aims to develop and validate new roof systems and green façades structured in expanded cork agglomerate (ICB), with a higher environmental and energy profile than conventional solutions and with a high capacity for energy customization and prefabrication. In these eco-designed systems, ICB will simultaneously provide: thermal insulation of the building; drainage functions; retention functions; and carbon capture.
Cork is a raw material that is so perfect that no industrial or technological processes have yet been able to replicate it. It has numerous advantages and benefits due to its key characteristics, and it represents an innovative opportunity to incorporate cork-based materials in green roof systems. Some of the cork’s key characteristics are:
Very light material—Over 50% of its volume is air, which makes it very light, it weighs just 0.16 grams per cubic centimeter and can float.
Elastic and compressible—It is the only solid that, when compressed on one side, does not increase in volume on another; and as a result of its elasticity, it is able to adapt, for example, to variations in temperature and pressure without suffering alterations.
Impermeable to liquids and gases—Thanks to the suberin and ceroids contained in the cell walls, cork is practically impermeable to liquids and gases. Its resistance to moisture enables it to age without deteriorating.
Thermal and acoustic insulator—Cork has low conductivity to heat, noise, and vibration. This is because the gaseous components contained in cork are enclosed in small impermeable compartments, isolated from each other by a moisture-resistant substance.
Fire retardant—Cork is also a natural fire retardant: it burns without a flame and does not emit toxic gases during combustion.
Highly abrasion-resistant—Cork is extremely resistant to abrasion and has a high friction coefficient. Thanks to its honeycomb structure, its resistance to impact or friction is greater than that of other hard surfaces.
Hypoallergenic—Because cork does not absorb dust, it helps protect against allergies and does not pose a risk to asthma sufferers.
Natural touch—The natural texture of cork combines softness and flexibility to the touch with a naturally uneven surface. The variable degree of irregularity is given by the type of cork used and the finish chosen.
The cork also plays an important role in Portuguese Economy, representing 2% of Portuguese total exports, and due to its sustainable, environmental, and economic benefits, it seems to be an excellent material to incorporate in the project, as well as the use of the GUL, in order to test it to the adaptation to a climate change in a school building.
It was important for LIFE-mybuildingisgreen project to address also the blue areas, from the perspective of water management, which may be due to the increase of the permeable areas (favorable to the infiltration of water into the soil), the reuse of rainwater, and the reduction of water for irrigation.
Following the solutions related to water, it would be important for the project to also contribute to the strengthening of this built urban relationship—permeabilized soil. In this context, urban ponds play an important role in the formation of small aquatic ecosystems of low demand and complexity.
The ponds are masses of standing water or very low current of a permanent or temporary nature, depending on the climate, the geology of the land, and the availability of water. The ponds are characterized by their low depth, total penetration of light into the water, possibility of occurrence of plants throughout their area, and absence of water stratification, and may originate from natural, geological or, ecological processes, or more commonly, as a result of human activities, intentional or not.
Ponds present themselves as a nature-based solution that act in water management in several dimensions: ensure the establishment of an aquatic ecosystem; ensure the availability of water (for fauna and flora); promote biodiversity; increase permeable area; boost water infiltration into the soil; and reduce the need for water for watering.
It has been decided to make systems superimposed on the façade that generate shadows in the gaps, preventing the direct incidence of solar rays, for this purpose canopies or cantilevered elements have been created, made up of NBS, plants, and plant species, in addition, so that the implantation of these elements does not prevent sunlight in the winter months, deciduous species have been used.
They consist of a removable modular substructure of laminated tubular frameworks, which support containers or pots with climbing plants, equipped with an irrigation system through pipelines adapted to the substructure. These systems are mainly constituted by a removable modular substructure of laminated tubular framework, of modules with dimensions 2x2 and 3 meters high, in hot galvanized steel profiles of 60.60 and 120.60, anchored to the façade and to the ground.
Formed by vertical elements (tubular steel pillars) and horizontal elements (crossbars and tubular steel beams), which support their own weight and that of the plant containers. It has been called FAVE (Vegetable Facade), in it, horizontal and vertical surfaces are generated on the holes and in front of them.
Two variants have been adapted in this system:
Containers or pots of guide plants, of the vine type, that upholster and generate surfaces that are opaque to the sun, will be arranged in the tubular framework. Two varieties of vines have been selected as guide plants:
Sketch of mBiFAVE 1″ systems (left). Sketch of mBiFAVE 2″ systems (right).
Vegetated awnings are arranged in the tubular framework, continuous surfaces on racks on which species grow superficially on both sides (Figure 4
The double vegetated awning is made up of:
Rectangular frame of 0.80 × 2.90 mt, made with hot-dip galvanized tubular steel, anchored to the substructure.
Leaf.skin tensioned membrane formed by anti-root PVC sheet fixed by linear clips on the frame.
Hydroponic geotextile substrate.
Lower gutter made of sheet steel, connected to a drain to collect excess water.
Irrigation system is installed at the top from where the water falls by gravity soaking the entire substrate. The water provides the fertilizer, keeping the vegetation in perfect condition.
Mixture of seeds that are projected on the geotextile, after a few months the membrane will be completely upholstered.
Three roof systems have been implemented, whose main function is to reduce the effects of solar radiation in the hot months and reduce energy losses in winter months and thus CO2 emissions and energy consumption in heating, easy to implement and adaptation to any building.
It is implanted on the existing flat roof, separated from it, generating an air chamber between both.
To do this, some racks are arranged, supported on concrete “plots”, on which we place removable “trays” that house a thin extensive roof solution, with an improved substrate in which native species are planted. The system is made up of:
Supports or plots: made in situ with concrete, with a height depending on the roof to achieve horizontal leveling of the frame.
Removable modular frame: made by means of a framework of hot-dip galvanized tubular steel, with approximate dimensions of 4.5 m long x 1 m wide, formed by stringers and crossbars.
Galvanized sheet steel trays: with side tabs for support (Figure 5).
Sketch of mBiCUVE 1″ system (left). The three roof systems: mBiCUVE 1, mBiCUVE 2, and mBiCUVE SUS (right).
A system similar to the mBiCUVE 1 system, as a variant on the racks, large containers would be implanted, at ends and intermediate points, where the two varieties of vines that we have used for planting are planted. Façade systems, mBiFAVE 1.
An extensive cover system is used with an improved substrate, including recycled aggregates for the realization of the cover drainage. A layer of protection, a drainage sheet, a filter, and the improved substrate in which native species are planted are placed on the waterproofing of the roof on which the action is being carried out.
By analyzing the existing conditions, namely strong solar incidence in classrooms and the great thermal discomfort associated with high thermal oscillation, the intervention goes through the installation green wall that will work with vegetation curtain. Also, due to pathologies at the level of existing roofs such as poor waterproofing and nonfunctional pendants, green roofs of three typologies will be installed: extended sloped coverage, extensive coverage with gul system, and a green cover with solar panels—Solar bio roof.
With the concern of closing the water cycle, the surplus of rainwater from two sloping roofs will be routed to two tanks and later, by gravity, to a pond of natural infiltration, located in Horta das Oliveiras. Thus, the water will be returned to the natural soil, being able to recharge the aquifers.
For the monitoring and study of the ecosystem services of green roofs, equipment such as a weather station, various thermal sensors and humidity, and caudameters will be installed.
Green roofing has increasingly established itself as an important element in the strategies of “Nature-based Solutions” for Portuguese cities, thanks to the numerous environmental, financial, and social benefits they present (Figure 6).
Blueprint of green roofs in EB1 do Falcão. In different greens the 3 green roofs prototypes: GUL system, solar bio roof, and sloping green roof (ANCV—Associação Nacional de Coberturas Verdes).
For the success of the implementation of mass green roofs in cities and for their dissemination and acceptance by the professional groups involved and the general population, it is essential that there are examples of model projects promoted by the municipalities themselves as a demonstration of their advantages and promotion of good implementation and maintenance practices.
The GUL roof will be installed with the innovative green roofing system with expanded cork agglomerate—ICB. The cork agglomerate, with 8 cm thickness, will perform the functions of drainage of excess water, thermal insulation, protection of waterproofing, and sound insulation. Using cork as a building material—biomaterial—this system captures carbon in its production cycle.
The substrate profile will be 12 cm and herbaceous species will be planted in alveole. The planting strategy aimed to promote biodiversity in the green cover. Perimeter gravel strips 30 cm wide will be installed.
The SOLAR BIOROOF green roof is a system that combines the installation of solar panels with the existence of vegetation. The substrate profile will have the thickness of 10 cm, where a pre-cultivated Sedum carpet will be installed. Perimeter strips of gravel with variable width between 22 and 30 cm will be performed.
The fixation of the solar panels will be carried out through solar bases with ballast, without drilling the slab, ensuring the tightness of the slab. The ballast will consist of 7 cm of river gravel. A counterweight life system is planned to be installed. This system consists of anchoring bases and steel cable, where the operators will have to secure themselves through sliding carts and harnesses. This system is also not intrusive, also ensuring the preservation of waterproofing.
The sloping green cover will be performed using the green roofing system up to 20° slope that holds supports to be installed along the lowest point of the cover. The substrate profile will be 10 cm and will be populated by the genus sedum in pre-cultivated carpet.
The excess water from the roofing system will be routed to a water tank.
Green facades for a pleasant atmosphere. Putting vegetation on the facades is so far something that is usually left to chance. Attractive growth systems can be built for micro-vertical gardens with some easy-to-assemble components made of high-quality stainless steel.
Green facades are attractive, ecologically sensitive, and useful. They create a shadow area on the façade which makes the temperature more mild. In the case of the EB 1 do Falcão, due to the sun exposure and size of the windows, the thermal conditions felt inside the building cause discomfort during the warmer months, especially in the classrooms. To lower the temperature, it was suggested the implementation of a wall of steel cables covered by a deciduous vine.
The species selected is
The vine is placed from 60 to 60 cm, being placed 10 feet along the façade, in a 50 cm wide construction site, supported by squares connected to the upper area of the façade from that extend stainless steel cables with a thickness of 6 mm and length of 6 meters. These cables have an intermediate attachment point on the balcony slab. As it is a small construction site, irrigation has been implemented using the drop-by-drop system.
The vegetation must be pruned to maintain its growth within the area assigned to it, at its base should be placed mulch and the weeds will have to be plucked.
The green wall structure should be composed of a cement or buried concrete base structure, about 20 cm. This 570 cm long piece will serve as a base anchorage for the steel cables installed by placing a 60-in-60 M10 eye. The 6 mm steel cable will be supported by two eyelets at each end, locking the cable with four 6 mm, two-wire cables at each end. Central fixation is placed through a third eye nailed to the building.
The construction of artificial lakes, creating water reserves for biodiverse purposes, are examples of fundamental hydraulic works in rational water management. In order to reduce the water losses of these structures, appropriate waterproofing techniques should be used (Figure 7).
Details of the mBiGPond—profile and top view of the pond.
The waterproofing of the pond is carried out with the placement of a geotextile fabric to prevent the rupture of the waterproofing screen. The water coming from two covers of the EB1 do Falcão, one with vegetation and the other without, is directed from the retention tanks to the lower level where the pond is located.
The vegetation proposed for this area will serve as a remediation plant, thus helping to maintain the quality of the water that is being infiltrated into the soil.
This space is of great importance because it creates a biodiverse area, where plants of riparian characteristics will arise and that small amphibians and insects can enjoy.
Both spaces will be areas of excellent learning opportunity for the students of the EB1 do Falcão, as they will be able to observe the natural dynamics present in this project, the change and cycles of nature, the emergence of new wildlife in the area of the pond, and the reduction of temperature inside their rooms, thus allowing greater thermal comfort.
With the execution of this project, the following results are expected:
Climate adaptation of the pilot buildings (three educational centers) through the implementation of NBS prototypes.
Well-being improvement and thermal comfort for around 1.000 citizens in the 3 pilot buildings and communities.
The elaboration of Reference Reports and Good Practice Manuals on the application of NBS in public buildings of education services for the 3 climatic risk areas of the EU.
For the entire Project it is expected to reduce the production of 27 Ton of CO2/year and 144 kg of NOx (reduction 20% and 7% respectively).
It will be collected about 2.700 m3/project of rainfall that represents 30% of each building.
Increase in the area of green areas in each building by approximately 0.5 ha.
Reduction of 50% of the energy costs for cooling and 10% for heating. This amount to 1000€/building.
Integration of NBS into regulations, action plans, and environmental programs
Execution of expert meetings, demonstration workshops, expert workshops, online seminars and transnational conferences, stakeholders training, website, publication of articles, connection with media associations, and videos.
The overall conclusion is that NBS can be a technical and scientific solution for this type of building allowing a more affordable and energy-efficient solution for the adaptation to climate change in Mediterranean regions.
It is already observed that the climate is changing, locally proved by the PIAAC study so it is time to act in order to use Mother Nature’s knowledge to prevent more damage to Earth’s environment.
Of particular relevance is the application in two study areas, Alentejo and Badajoz, since they correspond to two territories with the lowest population density and the lowest GDP in Portugal and Spain. In addition, these areas are suffering severe depopulation and economic crisis in their rural areas, so these technologies can help improve their social conditions.
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The cause was a new coronavirus. The World Health Organization (WHO) named the virus SARS-CoV-2 and COVID-19 the associated disease. In the first months of 2020, this disease became a pandemic with a high lethality reported. Since then, the search for treatments began. We started by searching among treatments previously approved for human use that were not designed for COVID-19 and were considered to treat this condition. We continued searching on the therapeutics guidelines published by the WHO for the management of infection by SARS-CoV-2. Based on these results, we searched for the literature in PubMed to obtain further evidence on the drugs against SARS-CoV-2. The treatments presented in this chapter are Ivermectin, Hydroxychloroquine, Nitazoxanide, Azithromycin, Molnupiravir, Casirivimab-Imdevimab, Ritonavir-Nirmatrelvir, Ritonavir-Lopinavir, Remdesivir, and Favipiravir. Two years ahead of the start of the COVID-19 pandemic, a plenty of options for treatment have been investigated. Only a few of them have been shown to be efficient and safe. According to the WHO, Ritonavir-Nirmatrelvir outperforms other proposed therapeutics.",book:{id:"11690",title:"COVID-19 Drug Development - Recent Advances, New Perspectives, and Applications",coverURL:"https://cdn.intechopen.com/books/images_new/11690.jpg"},signatures:"Nicolás Padilla-Raygoza, Gilberto Flores-Vargas, María de Jesús Gallardo-Luna, Efraín Navarro-Olivos, Francisco Javier Magos-Vázquez and Daniel Alberto Díaz-Martínez"},{id:"83054",title:"Pulsatory Liposome: A Possible Biotechnological Device",slug:"pulsatory-liposome-a-possible-biotechnological-device",totalDownloads:2,totalDimensionsCites:0,doi:"10.5772/intechopen.106347",abstract:"A unilamellar liposome filled with an osmotic solution is introduced into a hypotonic aqueous environment. Because of the mechanical tension induced by the osmotic flow, the vesicle swells up to a critical size, when suddenly a transbilayer pore appears and the vesicle relaxing stage starts. A part of the intracellular material leaks out through this pore, and the liposome membrane relaxes and finally recovers. The swelling begins again and the liposome experiences a periodical process. For this reason, we have named it a pulsatory liposome. The swelling of the liposome is described by a differential equation. All the processes which contribute to the vesicle relaxing and its coming back to the initial size are described by three differential equations. The pulsatory liposome can be programmed to work a number of cycles, established before. The activity of a pulsatory liposome can be characterized by the following parameters: (a) number of cycles, the length time of each cycle, and liposome activity life; (b) the length time of the swelling stage and the relaxation stage for each cycle; (c) the amount of solute leaked out through the pore in each cycle. The pulsatory liposome may be regarded as a two-stroke engine.",book:{id:"11814",title:"Liposomes - Recent Advances, New Perspectives and Applications",coverURL:"https://cdn.intechopen.com/books/images_new/11814.jpg"},signatures:"Dumitru Popescu and Alin Gabriel Popescu"},{id:"82962",title:"Pluralism Medical Treatment, Prevention, and Control of COVID-19 Infection and Its Long-Sufferings among the Older Adults in the Northeast of Thailand from 2019 to 2022",slug:"pluralism-medical-treatment-prevention-and-control-of-covid-19-infection-and-its-long-sufferings-amo",totalDownloads:51,totalDimensionsCites:0,doi:"10.5772/intechopen.106339",abstract:"COVID-19 in 2019 has brought both changes and challenges to the world. This global pandemic has an impact on people of all age levels, especially older adults. In Thailand, older persons are at high risk of COVID-19 infection. They are included in the so-called 608 groups. The objective of this review article was to synthesize and present medical pluralism, the development of drugs from herbs, and projects conducted to treat, prevent, and control the infection and long sufferings of COVID-19. The review covers 10 studies, three projects produced at Mahasarakham University, Chaiyaphum Rajabhat University, and Khon Kaen University that were reviewed, synthesized, and analyzed. The results of the synthesis indicate that modern and Thai traditional medicine can help reduce the severity of the infection and long sufferings of COVID-19. The medical pluralism between modern and Thai traditional medicine is needed to remedy COVID-19 cases among the older adults in the Northeast of Thailand.",book:{id:"11690",title:"COVID-19 Drug Development - Recent Advances, New Perspectives, and Applications",coverURL:"https://cdn.intechopen.com/books/images_new/11690.jpg"},signatures:"Pissamai Homchampa, Khemika Napattaradechanon, Parichat Yatniyom, Thawalrat Ratanasiri, Piyaporn Sansila, Thanawan Sirisuk, Thawalwong Ratanasiri and Amornrat Ratanasiri"},{id:"82353",title:"Pharmacovigilance of Biological Drugs",slug:"pharmacovigilance-of-biological-drugs",totalDownloads:8,totalDimensionsCites:0,doi:"10.5772/intechopen.105520",abstract:"The use of biological drugs has significantly increased over the past decades and has allowed for the treatment of many life-threatening and chronic diseases. The patent expiration of biological innovative medicines enables copies of these drugs called biosimilars. The availability of biosimilars enhances competition, with the potential to improve patient access to biological medications and contribute to the financial sustainability of the healthcare systems. Unlike equivalent drugs, biosimilars are not identical but similar to their innovator products because of the differences in the manufacturing process, which is a biological process. However, they are considered comparable to their originators in safety, quality characteristics, biological activity, and efficacy. The regulatory procedures used for generic drugs cannot be applied for biosimilars, so they are subjected to rigorous characterization as well as comparative clinical studies. Since they are highly complex molecules produced from living cells, even small change in the production process can have major implications on their safety and effectiveness profile, causing a potential risk of immune-based adverse reactions. For all these reasons, for biological drugs, a robust long-term pharmacovigilance system is necessary. It is desirable that in the future, there are further guidance and resolution of the ongoing discussions on biosimilar labeling, naming, pharmacovigilance and interchangeability/substitution, to ensure the appropriate use of these drugs in clinical practice.",book:{id:"11679",title:"Pharmacovigilance and Regulations",coverURL:"https://cdn.intechopen.com/books/images_new/11679.jpg"},signatures:"Simona Guerzoni, Flavia Lo Castro, Carlo Baraldi, Giuliana Colella and Luca Pani"},{id:"82868",title:"Recent Strategies for Ocular Drug Delivery: Promises and Challenges",slug:"recent-strategies-for-ocular-drug-delivery-promises-and-challenges",totalDownloads:9,totalDimensionsCites:0,doi:"10.5772/intechopen.106335",abstract:"Ocular diseases include various anterior and posterior segment diseases. Due to the unique anatomy and physiology of the eye, efficient ocular drug delivery is a great challenge to researchers. The emerging nanoscience is playing an important role in the development of novel strategies for ocular disease management. Various active molecules have been designed to associate with nanocarriers to overcome ocular barriers and interact with certain ocular tissues. In this chapter, highlights will be made on barrier to intraocular delivery, general pathways for ocular absorption, and factors affecting intraocular bioavailability. The recent attempts of nanotechnology for treating anterior and posterior ocular diseases will be explored. This will include nanomicelles, nanoparticles, nanosuspensions, vesicular systems, in situ gel, dendrimers, contact lenses, implants, microneedles, and cell-based delivery systems. In addition, gene-based ocular delivery systems will be discussed. In this chapter, we will also provide a comprehensive overview of drug-device combinations used for ocular diseases such as glaucoma, dry eye disease, infections, and inflammations. Furthermore, drug delivery devices for ocular surgeries are discussed. Finally, challenges and future prospective of ocular delivery systems will be explored.",book:{id:"11688",title:"Advances in Drug Delivery Methods",coverURL:"https://cdn.intechopen.com/books/images_new/11688.jpg"},signatures:"Amal H. El-Kamel and Asmaa A. Ashour"},{id:"82727",title:"Mesoporous Silica Based Cancer Theranostic: A Modern Approach in Upcoming Medicine",slug:"mesoporous-silica-based-cancer-theranostic-a-modern-approach-in-upcoming-medicine",totalDownloads:15,totalDimensionsCites:0,doi:"10.5772/intechopen.105447",abstract:"In case cancers are located deep inside the body and are very tough to diagnose, diagnostic tools like MRI/CT scans can be employed to detect these cancers. The major challenge in such cases is the delivery of MRI active agents or visualizing agents to the target site. In this context we will discuss different mesoporous nanoparticles that can be employed to target the tissue at a specific location, its functionalization to reach the target site (Folic acid), different simple dyes as well as specific dyes which offer theranostic functionality. The nanoparticles like mesoporous silica nanoparticles offer the possibility to load therapeutic and diagnostic agents. Its surface allow multiple functionalization and conjugations which offer target specific delivery of these agents. Moreover we will also overview different modern drug delivery inventions for offering theranostic application.",book:{id:"11688",title:"Advances in Drug Delivery Methods",coverURL:"https://cdn.intechopen.com/books/images_new/11688.jpg"},signatures:"Ajinkya Pote, Vikas Ahirrao and Vishal Pande"}],onlineFirstChaptersTotal:54},preDownload:{success:null,errors:{}},subscriptionForm:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[],offset:8,limit:8,total:0},allSeries:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:11,numberOfPublishedChapters:91,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:108,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:33,numberOfPublishedChapters:333,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:14,numberOfPublishedChapters:145,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:11,numberOfPublishedChapters:144,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!0},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:126,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:11,numberOfPublishedChapters:113,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:23,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2753-894X",doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:13,numberOfOpenTopics:1,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!0},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:5,numberOfUpcomingTopics:0,issn:"2753-6580",doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],testimonialsList:[{id:"13",text:"The collaboration with and support of the technical staff of IntechOpen is fantastic. 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",coverUrl:"https://cdn.intechopen.com/series/covers/22.jpg",latestPublicationDate:"August 17th, 2022",hasOnlineFirst:!0,numberOfPublishedBooks:1,editor:{id:"356540",title:"Prof.",name:"Taufiq",middleName:null,surname:"Choudhry",slug:"taufiq-choudhry",fullName:"Taufiq Choudhry",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000036X2hvQAC/Profile_Picture_2022-03-14T08:58:03.jpg",biography:"Prof. Choudhry holds a BSc degree in Economics from the University of Iowa, as well as a Masters and Ph.D. in Applied Economics from Clemson University, USA. In January 2006, he became a Professor of Finance at the University of Southampton Business School. He was previously a Professor of Finance at the University of Bradford Management School. He has over 80 articles published in international finance and economics journals. His research interests and specialties include financial econometrics, financial economics, international economics and finance, housing markets, financial markets, among others.",institutionString:null,institution:{name:"University of Southampton",institutionURL:null,country:{name:"United Kingdom"}}},editorTwo:null,editorThree:null},subseries:{paginationCount:3,paginationItems:[{id:"86",title:"Business and Management",coverUrl:"https://cdn.intechopen.com/series_topics/covers/86.jpg",isOpenForSubmission:!0,editor:{id:"128342",title:"Prof.",name:"Vito",middleName:null,surname:"Bobek",slug:"vito-bobek",fullName:"Vito Bobek",profilePictureURL:"https://mts.intechopen.com/storage/users/128342/images/system/128342.jpg",biography:"Dr. Vito Bobek works as an international management professor at the University of Applied Sciences FH Joanneum, Graz, Austria. He has published more than 400 works in his academic career and visited twenty-two universities worldwide as a visiting professor. Dr. Bobek is a member of the editorial boards of six international journals and a member of the Strategic Council of the Minister of Foreign Affairs of the Republic of Slovenia. He has a long history in academia, consulting, and entrepreneurship. His own consulting firm, Palemid, has managed twenty significant projects, such as Cooperation Program Interreg V-A (Slovenia-Austria) and Capacity Building for the Serbian Chamber of Enforcement Agents. He has also participated in many international projects in Italy, Germany, Great Britain, the United States, Spain, Turkey, France, Romania, Croatia, Montenegro, Malaysia, and China. Dr. Bobek is also a co-founder of the Academy of Regional Management in Slovenia.",institutionString:"Universities of Applied Sciences FH Joanneum, Austria",institution:{name:"Universities of Applied Sciences Joanneum",institutionURL:null,country:{name:"Austria"}}},editorTwo:{id:"293992",title:"Dr.",name:"Tatjana",middleName:null,surname:"Horvat",slug:"tatjana-horvat",fullName:"Tatjana Horvat",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002hXb0hQAC/Profile_Picture_1642419002203",biography:"Tatjana Horvat works as a professor for accountant and auditing at the University of Primorska, Slovenia. She is a Certified State Internal Auditor (licensed by Ministry of Finance RS) and Certified Internal Auditor for Business Sector and Certified accountant (licensed by Slovenian Institute of Auditors). At the Ministry of Justice of Slovenia, she is a member of examination boards for court expert candidates and judicial appraisers in the following areas: economy/finance, valuation of companies, banking, and forensic investigation of economic operations/accounting. At the leading business newspaper Finance in Slovenia (Swedish ownership), she is the editor and head of the area for business, finance, tax-related articles, and educational programs.",institutionString:null,institution:{name:"University of Primorska",institutionURL:null,country:{name:"Slovenia"}}},editorThree:null},{id:"87",title:"Economics",coverUrl:"https://cdn.intechopen.com/series_topics/covers/87.jpg",isOpenForSubmission:!0,editor:{id:"327730",title:"Prof.",name:"Jaime",middleName:null,surname:"Ortiz",slug:"jaime-ortiz",fullName:"Jaime Ortiz",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00002zaOKZQA2/Profile_Picture_1642145584421",biography:"Dr. Jaime Ortiz holds degrees from Chile, the Netherlands, and the United States. He has held tenured faculty, distinguished professorship, and executive leadership appointments in several universities around the world. Dr. Ortiz has previously worked for international organizations and non-government entities in economic and business matters, and he has university-wide globalization engagement in more than thirty-six countries. He has advised, among others, the United Nations Development Program, Inter-American Development Bank, Organization of American States, Pre-investment Organization of Latin America and the Caribbean, Technical Cooperation of the Suisse Government, and the World Bank. Dr. Ortiz is the author, co-author, or editor of books, book chapters, textbooks, research monographs and technical reports, and refereed journal articles. He is listed in Who’s Who in the World, Who’s Who in America, Who’s Who in Finance and Business, Who’s Who in Business Higher Education, Who’s Who in American Education, and Who’s Who Directory of Economists. Dr. Ortiz has been a Fulbright Scholar and an MSI Leadership Fellow with the W.K. Kellogg Foundation. His teaching interests revolve around global economies and markets while his research focuses on topics related to development and growth, global business decisions, and the economics of technical innovation.",institutionString:null,institution:{name:"University of Houston",institutionURL:null,country:{name:"United States of America"}}},editorTwo:null,editorThree:null},{id:"88",title:"Marketing",coverUrl:"https://cdn.intechopen.com/series_topics/covers/88.jpg",isOpenForSubmission:!0,editor:{id:"203609",title:"Associate Prof.",name:"Hanna",middleName:null,surname:"Gorska-Warsewicz",slug:"hanna-gorska-warsewicz",fullName:"Hanna Gorska-Warsewicz",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSD9pQAG/Profile_Picture_2022-06-14T11:58:32.jpeg",biography:"Hanna Górska-Warsewicz, Ph.D. is Associate Professor at Warsaw University of Life Sciences and Head of Department of Food Market and Consumption Research. She specializes in the subject of brands, brand equity, and brand management in production, service, and trade enterprises. She combines this subject with marketing and marketing management in both theoretical and practical aspects. Prof. Hanna Górska-Warsewicz also analyzes brands in the context of trademarks, legal regulations and the protection of intangible. She is an author or co-author of over 200 publications in this field, including 8 books. 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Samim Al Azad and Slimane Ed-dafali",hash:"86a6d33cf601587e591064ce92effc02",volumeInSeries:1,fullTitle:"Leadership in a Changing World - A Multidimensional Perspective",editors:[{id:"418514",title:"Dr.",name:"Muhammad",middleName:null,surname:"Mohiuddin",slug:"muhammad-mohiuddin",fullName:"Muhammad Mohiuddin",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000038UqSfQAK/Profile_Picture_2022-05-13T10:39:03.jpg",biography:"Dr. Muhammad Mohiuddin is an Associate Professor of International Business at Laval University, Canada. He has taught at Thompson Rivers University, Canada; University of Paris-Est, France; Osnabruck University of Applied Science, Germany; and Shanghai Institute of Technology and Tianjin University of Technology, China. He has published research in Research Policy, Applied Economics, Review of Economic Philosophy, Strategic Change, International Journal of Logistics, Sustainability, Journal of Environmental Management, Journal of Global Information Management, Journal of Cleaner Production, M@N@GEMENT, and more. He is a member of CEDIMES Institut (France), Academy of International Business (AIB), Strategic Management Society (SMS), Academy of Management (AOM), Administrative Science Association of Canada (ASAC), and Canadian council of small business and entrepreneurship (CCSBE). He is currently the director of the Research Group on Contemporary Asia (GERAC) at Laval University. 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Radiotherapy and Nuclear Medicine Technology has always been my aspiration and my life. As years passed I accumulated a tremendous amount of skills and knowledge in Radiotherapy and Nuclear Medicine, Conventional Radiology, Radiation Protection, Bioinformatics Technology, PACS, Image processing, clinically and lecturing that will enable me to provide a valuable service to the community as a Researcher and Consultant in this field. My method of translating this into day to day in clinical practice is non-exhaustible and my habit of exchanging knowledge and expertise with others in those fields is the code and secret of success.",institutionString:null,institution:{name:"Majmaah University",country:{name:"Saudi Arabia"}}},{id:"313277",title:"Dr.",name:"Bartłomiej",middleName:null,surname:"Płaczek",slug:"bartlomiej-placzek",fullName:"Bartłomiej Płaczek",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/313277/images/system/313277.jpg",biography:"Bartłomiej Płaczek, MSc (2002), Ph.D. (2005), Habilitation (2016), is a professor at the University of Silesia, Institute of Computer Science, Poland, and an expert from the National Centre for Research and Development. His research interests include sensor networks, smart sensors, intelligent systems, and image processing with applications in healthcare and medicine. He is the author or co-author of more than seventy papers in peer-reviewed journals and conferences as well as the co-author of several books. He serves as a reviewer for many scientific journals, international conferences, and research foundations. Since 2010, Dr. Placzek has been a reviewer of grants and projects (including EU projects) in the field of information technologies.",institutionString:"University of Silesia",institution:{name:"University of Silesia",country:{name:"Poland"}}},{id:"35000",title:"Prof.",name:"Ulrich H.P",middleName:"H.P.",surname:"Fischer",slug:"ulrich-h.p-fischer",fullName:"Ulrich H.P Fischer",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/35000/images/3052_n.jpg",biography:"Academic and Professional Background\nUlrich H. P. has Diploma and PhD degrees in Physics from the Free University Berlin, Germany. He has been working on research positions in the Heinrich-Hertz-Institute in Germany. Several international research projects has been performed with European partners from France, Netherlands, Norway and the UK. He is currently Professor of Communications Systems at the Harz University of Applied Sciences, Germany.\n\nPublications and Publishing\nHe has edited one book, a special interest book about ‘Optoelectronic Packaging’ (VDE, Berlin, Germany), and has published over 100 papers and is owner of several international patents for WDM over POF key elements.\n\nKey Research and Consulting Interests\nUlrich’s research activity has always been related to Spectroscopy and Optical Communications Technology. Specific current interests include the validation of complex instruments, and the application of VR technology to the development and testing of measurement systems. He has been reviewer for several publications of the Optical Society of America\\'s including Photonics Technology Letters and Applied Optics.\n\nPersonal Interests\nThese include motor cycling in a very relaxed manner and performing martial arts.",institutionString:null,institution:{name:"Charité",country:{name:"Germany"}}},{id:"341622",title:"Ph.D.",name:"Eduardo",middleName:null,surname:"Rojas Alvarez",slug:"eduardo-rojas-alvarez",fullName:"Eduardo Rojas Alvarez",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/341622/images/15892_n.jpg",biography:null,institutionString:null,institution:{name:"University of Cuenca",country:{name:"Ecuador"}}},{id:"215610",title:"Prof.",name:"Muhammad",middleName:null,surname:"Sarfraz",slug:"muhammad-sarfraz",fullName:"Muhammad Sarfraz",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/215610/images/system/215610.jpeg",biography:"Muhammad Sarfraz is a professor in the Department of Information Science, Kuwait University. His research interests include computer graphics, computer vision, image processing, machine learning, pattern recognition, soft computing, data science, intelligent systems, information technology, and information systems. Prof. Sarfraz has been a keynote/invited speaker on various platforms around the globe. He has advised various students for their MSc and Ph.D. theses. He has published more than 400 publications as books, journal articles, and conference papers. He is a member of various professional societies and a chair and member of the International Advisory Committees and Organizing Committees of various international conferences. Prof. Sarfraz is also an editor-in-chief and editor of various international journals.",institutionString:"Kuwait University",institution:{name:"Kuwait University",country:{name:"Kuwait"}}},{id:"32650",title:"Prof.",name:"Lukas",middleName:"Willem",surname:"Snyman",slug:"lukas-snyman",fullName:"Lukas Snyman",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/32650/images/4136_n.jpg",biography:"Lukas Willem Snyman received his basic education at primary and high schools in South Africa, Eastern Cape. He enrolled at today's Nelson Metropolitan University and graduated from this university with a BSc in Physics and Mathematics, B.Sc Honors in Physics, MSc in Semiconductor Physics, and a Ph.D. in Semiconductor Physics in 1987. After his studies, he chose an academic career and devoted his energy to the teaching of physics to first, second, and third-year students. After positions as a lecturer at the University of Port Elizabeth, he accepted a position as Associate Professor at the University of Pretoria, South Africa.\r\n\r\nIn 1992, he motivates the concept of 'television and computer-based education” as means to reach large student numbers with only the best of teaching expertise and publishes an article on the concept in the SA Journal of Higher Education of 1993 (and later in 2003). The University of Pretoria subsequently approved a series of test projects on the concept with outreach to Mamelodi and Eerste Rust in 1993. In 1994, the University established a 'Unit for Telematic Education ' as a support section for multiple faculties at the University of Pretoria. In subsequent years, the concept of 'telematic education” subsequently becomes well established in academic circles in South Africa, grew in popularity, and is adopted by many universities and colleges throughout South Africa as a medium of enhancing education and training, as a method to reaching out to far out communities, and as a means to enhance study from the home environment.\r\n\r\nProfessor Snyman in subsequent years pursued research in semiconductor physics, semiconductor devices, microelectronics, and optoelectronics.\r\n\r\nIn 2000 he joined the TUT as a full professor. Here served for a period as head of the Department of Electronic Engineering. Here he makes contributions to solar energy development, microwave and optoelectronic device development, silicon photonics, as well as contributions to new mobile telecommunication systems and network planning in SA.\r\n\r\nCurrently, he teaches electronics and telecommunications at the TUT to audiences ranging from first-year students to Ph.D. level.\r\n\r\nFor his research in the field of 'Silicon Photonics” since 1990, he has published (as author and co-author) about thirty internationally reviewed articles in scientific journals, contributed to more than forty international conferences, about 25 South African provisional patents (as inventor and co-inventor), 8 PCT international patent applications until now. Of these, two USA patents applications, two European Patents, two Korean patents, and ten SA patents have been granted. A further 4 USA patents, 5 European patents, 3 Korean patents, 3 Chinese patents, and 3 Japanese patents are currently under consideration.\r\n\r\nRecently he has also published an extensive scholarly chapter in an internet open access book on 'Integrating Microphotonic Systems and MOEMS into standard Silicon CMOS Integrated circuitry”.\r\n\r\nFurthermore, Professor Snyman recently steered a new initiative at the TUT by introducing a 'Laboratory for Innovative Electronic Systems ' at the Department of Electrical Engineering. The model of this laboratory or center is to primarily combine outputs as achieved by high-level research with lower-level system development and entrepreneurship in a technical university environment. Students are allocated to projects at different levels with PhDs and Master students allocated to the generation of new knowledge and new technologies, while students at the diploma and Baccalaureus level are allocated to electronic systems development with a direct and a near application for application in industry or the commercial and public sectors in South Africa.\r\n\r\nProfessor Snyman received the WIRSAM Award of 1983 and the WIRSAM Award in 1985 in South Africa for best research papers by a young scientist at two international conferences on electron microscopy in South Africa. He subsequently received the SA Microelectronics Award for the best dissertation emanating from studies executed at a South African university in the field of Physics and Microelectronics in South Africa in 1987. In October of 2011, Professor Snyman received the prestigious Institutional Award for 'Innovator of the Year” for 2010 at the Tshwane University of Technology, South Africa. This award was based on the number of patents recognized and granted by local and international institutions as well as for his contributions concerning innovation at the TUT.",institutionString:null,institution:{name:"University of South Africa",country:{name:"South Africa"}}},{id:"317279",title:"Mr.",name:"Ali",middleName:"Usama",surname:"Syed",slug:"ali-syed",fullName:"Ali Syed",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/317279/images/16024_n.png",biography:"A creative, talented, and innovative young professional who is dedicated, well organized, and capable research fellow with two years of experience in graduate-level research, published in engineering journals and book, with related expertise in Bio-robotics, equally passionate about the aesthetics of the mechanical and electronic system, obtained expertise in the use of MS Office, MATLAB, SolidWorks, LabVIEW, Proteus, Fusion 360, having a grasp on python, C++ and assembly language, possess proven ability in acquiring research grants, previous appointments with social and educational societies with experience in administration, current affiliations with IEEE and Web of Science, a confident presenter at conferences and teacher in classrooms, able to explain complex information to audiences of all levels.",institutionString:null,institution:{name:"Air University",country:{name:"Pakistan"}}},{id:"75526",title:"Ph.D.",name:"Zihni Onur",middleName:null,surname:"Uygun",slug:"zihni-onur-uygun",fullName:"Zihni Onur Uygun",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/75526/images/12_n.jpg",biography:"My undergraduate education and my Master of Science educations at Ege University and at Çanakkale Onsekiz Mart University have given me a firm foundation in Biochemistry, Analytical Chemistry, Biosensors, Bioelectronics, Physical Chemistry and Medicine. After obtaining my degree as a MSc in analytical chemistry, I started working as a research assistant in Ege University Medical Faculty in 2014. In parallel, I enrolled to the MSc program at the Department of Medical Biochemistry at Ege University to gain deeper knowledge on medical and biochemical sciences as well as clinical chemistry in 2014. In my PhD I deeply researched on biosensors and bioelectronics and finished in 2020. Now I have eleven SCI-Expanded Index published papers, 6 international book chapters, referee assignments for different SCIE journals, one international patent pending, several international awards, projects and bursaries. In parallel to my research assistant position at Ege University Medical Faculty, Department of Medical Biochemistry, in April 2016, I also founded a Start-Up Company (Denosens Biotechnology LTD) by the support of The Scientific and Technological Research Council of Turkey. Currently, I am also working as a CEO in Denosens Biotechnology. The main purposes of the company, which carries out R&D as a research center, are to develop new generation biosensors and sensors for both point-of-care diagnostics; such as glucose, lactate, cholesterol and cancer biomarker detections. My specific experimental and instrumental skills are Biochemistry, Biosensor, Analytical Chemistry, Electrochemistry, Mobile phone based point-of-care diagnostic device, POCTs and Patient interface designs, HPLC, Tandem Mass Spectrometry, Spectrophotometry, ELISA.",institutionString:null,institution:{name:"Ege University",country:{name:"Turkey"}}},{id:"267434",title:"Dr.",name:"Rohit",middleName:null,surname:"Raja",slug:"rohit-raja",fullName:"Rohit Raja",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/267434/images/system/267434.jpg",biography:"Dr. Rohit Raja received Ph.D. in Computer Science and Engineering from Dr. CVRAMAN University in 2016. His main research interest includes Face recognition and Identification, Digital Image Processing, Signal Processing, and Networking. Presently he is working as Associate Professor in IT Department, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur (CG), India. He has authored several Journal and Conference Papers. He has good Academics & Research experience in various areas of CSE and IT. He has filed and successfully published 27 Patents. He has received many time invitations to be a Guest at IEEE Conferences. He has published 100 research papers in various International/National Journals (including IEEE, Springer, etc.) and Proceedings of the reputed International/ National Conferences (including Springer and IEEE). He has been nominated to the board of editors/reviewers of many peer-reviewed and refereed Journals (including IEEE, Springer).",institutionString:"Guru Ghasidas Vishwavidyalaya",institution:{name:"Guru Ghasidas Vishwavidyalaya",country:{name:"India"}}},{id:"246502",title:"Dr.",name:"Jaya T.",middleName:"T",surname:"Varkey",slug:"jaya-t.-varkey",fullName:"Jaya T. Varkey",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/246502/images/11160_n.jpg",biography:"Jaya T. Varkey, PhD, graduated with a degree in Chemistry from Cochin University of Science and Technology, Kerala, India. She obtained a PhD in Chemistry from the School of Chemical Sciences, Mahatma Gandhi University, Kerala, India, and completed a post-doctoral fellowship at the University of Minnesota, USA. She is a research guide at Mahatma Gandhi University and Associate Professor in Chemistry, St. Teresa’s College, Kochi, Kerala, India.\nDr. Varkey received a National Young Scientist award from the Indian Science Congress (1995), a UGC Research award (2016–2018), an Indian National Science Academy (INSA) Visiting Scientist award (2018–2019), and a Best Innovative Faculty award from the All India Association for Christian Higher Education (AIACHE) (2019). She Hashas received the Sr. Mary Cecil prize for best research paper three times. She was also awarded a start-up to develop a tea bag water filter. \nDr. Varkey has published two international books and twenty-seven international journal publications. She is an editorial board member for five international journals.",institutionString:"St. Teresa’s College",institution:null},{id:"250668",title:"Dr.",name:"Ali",middleName:null,surname:"Nabipour Chakoli",slug:"ali-nabipour-chakoli",fullName:"Ali Nabipour Chakoli",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/250668/images/system/250668.jpg",biography:"Academic Qualification:\r\n•\tPhD in Materials Physics and Chemistry, From: Sep. 2006, to: Sep. 2010, School of Materials Science and Engineering, Harbin Institute of Technology, Thesis: Structure and Shape Memory Effect of Functionalized MWCNTs/poly (L-lactide-co-ε-caprolactone) Nanocomposites. Supervisor: Prof. Wei Cai,\r\n•\tM.Sc in Applied Physics, From: 1996, to: 1998, Faculty of Physics & Nuclear Science, Amirkabir Uni. of Technology, Tehran, Iran, Thesis: Determination of Boron in Micro alloy Steels with solid state nuclear track detectors by neutron induced auto radiography, Supervisors: Dr. M. Hosseini Ashrafi and Dr. A. Hosseini.\r\n•\tB.Sc. in Applied Physics, From: 1991, to: 1996, Faculty of Physics & Nuclear Science, Amirkabir Uni. of Technology, Tehran, Iran, Thesis: Design of shielding for Am-Be neutron sources for In Vivo neutron activation analysis, Supervisor: Dr. M. Hosseini Ashrafi.\r\n\r\nResearch Experiences:\r\n1.\tNanomaterials, Carbon Nanotubes, Graphene: Synthesis, Functionalization and Characterization,\r\n2.\tMWCNTs/Polymer Composites: Fabrication and Characterization, \r\n3.\tShape Memory Polymers, Biodegradable Polymers, ORC, Collagen,\r\n4.\tMaterials Analysis and Characterizations: TEM, SEM, XPS, FT-IR, Raman, DSC, DMA, TGA, XRD, GPC, Fluoroscopy, \r\n5.\tInteraction of Radiation with Mater, Nuclear Safety and Security, NDT(RT),\r\n6.\tRadiation Detectors, Calibration (SSDL),\r\n7.\tCompleted IAEA e-learning Courses:\r\nNuclear Security (15 Modules),\r\nNuclear Safety:\r\nTSA 2: Regulatory Protection in Occupational Exposure,\r\nTips & Tricks: Radiation Protection in Radiography,\r\nSafety and Quality in Radiotherapy,\r\nCourse on Sealed Radioactive Sources,\r\nCourse on Fundamentals of Environmental Remediation,\r\nCourse on Planning for Environmental Remediation,\r\nKnowledge Management Orientation Course,\r\nFood Irradiation - Technology, Applications and Good Practices,\r\nEmployment:\r\nFrom 2010 to now: Academic staff, Nuclear Science and Technology Research Institute, Kargar Shomali, Tehran, Iran, P.O. Box: 14395-836.\r\nFrom 1997 to 2006: Expert of Materials Analysis and Characterization. Research Center of Agriculture and Medicine. Rajaeeshahr, Karaj, Iran, P. O. Box: 31585-498.",institutionString:"Atomic Energy Organization of Iran",institution:{name:"Atomic Energy Organization of Iran",country:{name:"Iran"}}},{id:"248279",title:"Dr.",name:"Monika",middleName:"Elzbieta",surname:"Machoy",slug:"monika-machoy",fullName:"Monika Machoy",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/248279/images/system/248279.jpeg",biography:"Monika Elżbieta Machoy, MD, graduated with distinction from the Faculty of Medicine and Dentistry at the Pomeranian Medical University in 2009, defended her PhD thesis with summa cum laude in 2016 and is currently employed as a researcher at the Department of Orthodontics of the Pomeranian Medical University. She expanded her professional knowledge during a one-year scholarship program at the Ernst Moritz Arndt University in Greifswald, Germany and during a three-year internship at the Technical University in Dresden, Germany. She has been a speaker at numerous orthodontic conferences, among others, American Association of Orthodontics, European Orthodontic Symposium and numerous conferences of the Polish Orthodontic Society. She conducts research focusing on the effect of orthodontic treatment on dental and periodontal tissues and the causes of pain in orthodontic patients.",institutionString:"Pomeranian Medical University",institution:{name:"Pomeranian Medical University",country:{name:"Poland"}}},{id:"252743",title:"Prof.",name:"Aswini",middleName:"Kumar",surname:"Kar",slug:"aswini-kar",fullName:"Aswini Kar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/252743/images/10381_n.jpg",biography:"uploaded in cv",institutionString:null,institution:{name:"KIIT University",country:{name:"India"}}},{id:"204256",title:"Dr.",name:"Anil",middleName:"Kumar",surname:"Kumar Sahu",slug:"anil-kumar-sahu",fullName:"Anil Kumar Sahu",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/204256/images/14201_n.jpg",biography:"I have nearly 11 years of research and teaching experience. I have done my master degree from University Institute of Pharmacy, Pt. Ravi Shankar Shukla University, Raipur, Chhattisgarh India. I have published 16 review and research articles in international and national journals and published 4 chapters in IntechOpen, the world’s leading publisher of Open access books. I have presented many papers at national and international conferences. I have received research award from Indian Drug Manufacturers Association in year 2015. My research interest extends from novel lymphatic drug delivery systems, oral delivery system for herbal bioactive to formulation optimization.",institutionString:null,institution:{name:"Chhattisgarh Swami Vivekanand Technical University",country:{name:"India"}}},{id:"253468",title:"Dr.",name:"Mariusz",middleName:null,surname:"Marzec",slug:"mariusz-marzec",fullName:"Mariusz Marzec",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/253468/images/system/253468.png",biography:"An assistant professor at Department of Biomedical Computer Systems, at Institute of Computer Science, Silesian University in Katowice. Scientific interests: computer analysis and processing of images, biomedical images, databases and programming languages. He is an author and co-author of scientific publications covering analysis and processing of biomedical images and development of database systems.",institutionString:"University of Silesia",institution:{name:"University of Silesia",country:{name:"Poland"}}},{id:"212432",title:"Prof.",name:"Hadi",middleName:null,surname:"Mohammadi",slug:"hadi-mohammadi",fullName:"Hadi Mohammadi",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/212432/images/system/212432.jpeg",biography:"Dr. Hadi Mohammadi is a biomedical engineer with hands-on experience in the design and development of many engineering structures and medical devices through various projects that he has been involved in over the past twenty years. Dr. Mohammadi received his BSc. and MSc. degrees in Mechanical Engineering from Sharif University of Technology, Tehran, Iran, and his PhD. degree in Biomedical Engineering (biomaterials) from the University of Western Ontario. He was a postdoctoral trainee for almost four years at University of Calgary and Harvard Medical School. He is an industry innovator having created the technology to produce lifelike synthetic platforms that can be used for the simulation of almost all cardiovascular reconstructive surgeries. He’s been heavily involved in the design and development of cardiovascular devices and technology for the past 10 years. He is currently an Assistant Professor with the University of British Colombia, Canada.",institutionString:"University of British Columbia",institution:{name:"University of British Columbia",country:{name:"Canada"}}},{id:"254463",title:"Prof.",name:"Haisheng",middleName:null,surname:"Yang",slug:"haisheng-yang",fullName:"Haisheng Yang",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/254463/images/system/254463.jpeg",biography:"Haisheng Yang, Ph.D., Professor and Director of the Department of Biomedical Engineering, College of Life Science and Bioengineering, Beijing University of Technology. He received his Ph.D. degree in Mechanics/Biomechanics from Harbin Institute of Technology (jointly with University of California, Berkeley). Afterwards, he worked as a Postdoctoral Research Associate in the Purdue Musculoskeletal Biology and Mechanics Lab at the Department of Basic Medical Sciences, Purdue University, USA. He also conducted research in the Research Centre of Shriners Hospitals for Children-Canada at McGill University, Canada. Dr. Yang has over 10 years research experience in orthopaedic biomechanics and mechanobiology of bone adaptation and regeneration. He earned an award from Beijing Overseas Talents Aggregation program in 2017 and serves as Beijing Distinguished Professor.",institutionString:null,institution:{name:"Beijing University of Technology",country:{name:"China"}}},{id:"89721",title:"Dr.",name:"Mehmet",middleName:"Cuneyt",surname:"Ozmen",slug:"mehmet-ozmen",fullName:"Mehmet Ozmen",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/89721/images/7289_n.jpg",biography:null,institutionString:null,institution:{name:"Gazi University",country:{name:"Turkey"}}},{id:"265335",title:"Mr.",name:"Stefan",middleName:"Radnev",surname:"Stefanov",slug:"stefan-stefanov",fullName:"Stefan Stefanov",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/265335/images/7562_n.jpg",biography:null,institutionString:null,institution:{name:"Medical University Plovdiv",country:{name:"Bulgaria"}}},{id:"242893",title:"Ph.D. Student",name:"Joaquim",middleName:null,surname:"De Moura",slug:"joaquim-de-moura",fullName:"Joaquim De Moura",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/242893/images/7133_n.jpg",biography:"Joaquim de Moura received his degree in Computer Engineering in 2014 from the University of A Coruña (Spain). In 2016, he received his M.Sc degree in Computer Engineering from the same university. He is currently pursuing his Ph.D degree in Computer Science in a collaborative project between ophthalmology centers in Galicia and the University of A Coruña. His research interests include computer vision, machine learning algorithms and analysis and medical imaging processing of various kinds.",institutionString:null,institution:{name:"University of A Coruña",country:{name:"Spain"}}},{id:"294334",title:"B.Sc.",name:"Marc",middleName:null,surname:"Bruggeman",slug:"marc-bruggeman",fullName:"Marc Bruggeman",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/294334/images/8242_n.jpg",biography:"Chemical engineer graduate, with a passion for material science and specific interest in polymers - their near infinite applications intrigue me. \n\nI plan to continue my scientific career in the field of polymeric biomaterials as I am fascinated by intelligent, bioactive and biomimetic materials for use in both consumer and medical applications.",institutionString:null,institution:null},{id:"255757",title:"Dr.",name:"Igor",middleName:"Victorovich",surname:"Lakhno",slug:"igor-lakhno",fullName:"Igor Lakhno",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/255757/images/system/255757.jpg",biography:"Igor Victorovich Lakhno was born in 1971 in Kharkiv (Ukraine). \nMD – 1994, Kharkiv National Medical Univesity.\nOb&Gyn; – 1997, master courses in Kharkiv Medical Academy of Postgraduate Education.\nPh.D. – 1999, Kharkiv National Medical Univesity.\nDSC – 2019, PL Shupik National Academy of Postgraduate Education \nProfessor – 2021, Department of Obstetrics and Gynecology of VN Karazin Kharkiv National University\nHead of Department – 2021, Department of Perinatology, Obstetrics and gynecology of Kharkiv Medical Academy of Postgraduate Education\nIgor Lakhno has been graduated from international training courses on reproductive medicine and family planning held at Debrecen University (Hungary) in 1997. Since 1998 Lakhno Igor has worked as an associate professor in the department of obstetrics and gynecology of VN Karazin National University and an associate professor of the perinatology, obstetrics, and gynecology department of Kharkiv Medical Academy of Postgraduate Education. Since June 2019 he’s been a professor in the department of obstetrics and gynecology of VN Karazin National University and a professor of the perinatology, obstetrics, and gynecology department. He’s affiliated with Kharkiv Medical Academy of Postgraduate Education as a Head of Department from November 2021. Igor Lakhno has participated in several international projects on fetal non-invasive electrocardiography (with Dr. J. A. Behar (Technion), Prof. D. Hoyer (Jena University), and José Alejandro Díaz Méndez (National Institute of Astrophysics, Optics, and Electronics, Mexico). He’s an author of about 200 printed works and there are 31 of them in Scopus or Web of Science databases. Igor Lakhno is a member of the Editorial Board of Reproductive Health of Woman, Emergency Medicine, and Technology Transfer Innovative Solutions in Medicine (Estonia). He is a medical Editor of “Z turbotoyu pro zhinku”. Igor Lakhno is a reviewer of the Journal of Obstetrics and Gynaecology (Taylor and Francis), British Journal of Obstetrics and Gynecology (Wiley), Informatics in Medicine Unlocked (Elsevier), The Journal of Obstetrics and Gynecology Research (Wiley), Endocrine, Metabolic & Immune Disorders-Drug Targets (Bentham Open), The Open Biomedical Engineering Journal (Bentham Open), etc. He’s defended a dissertation for a DSc degree “Pre-eclampsia: prediction, prevention, and treatment”. Three years ago Igor Lakhno has participated in a training course on innovative technologies in medical education at Lublin Medical University (Poland). Lakhno Igor has participated as a speaker in several international conferences and congresses (International Conference on Biological Oscillations April 10th-14th 2016, Lancaster, UK, The 9th conference of the European Study Group on Cardiovascular Oscillations). His main scientific interests: are obstetrics, women’s health, fetal medicine, and cardiovascular medicine. \nIgor Lakhno is a consultant at Kharkiv municipal perinatal center. He’s graduated from training courses on endoscopy in gynecology. He has 28 years of practical experience in the field.",institutionString:null,institution:null},{id:"244950",title:"Dr.",name:"Salvatore",middleName:null,surname:"Di Lauro",slug:"salvatore-di-lauro",fullName:"Salvatore Di Lauro",position:null,profilePictureURL:"https://intech-files.s3.amazonaws.com/0030O00002bSF1HQAW/ProfilePicture%202021-12-20%2014%3A54%3A14.482",biography:"Name:\n\tSALVATORE DI LAURO\nAddress:\n\tHospital Clínico Universitario Valladolid\nAvda Ramón y Cajal 3\n47005, Valladolid\nSpain\nPhone number: \nFax\nE-mail:\n\t+34 983420000 ext 292\n+34 983420084\nsadilauro@live.it\nDate and place of Birth:\nID Number\nMedical Licence \nLanguages\t09-05-1985. Villaricca (Italy)\n\nY1281863H\n474707061\nItalian (native language)\nSpanish (read, written, spoken)\nEnglish (read, written, spoken)\nPortuguese (read, spoken)\nFrench (read)\n\t\t\nCurrent position (title and company)\tDate (Year)\nVitreo-Retinal consultant in ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl. National Health System.\nVitreo-Retinal consultant in ophthalmology. Instituto Oftalmologico Recoletas. Red Hospitalaria Recoletas. Private practise.\t2017-today\n\n2019-today\n\t\n\t\nEducation (High school, university and postgraduate training > 3 months)\tDate (Year)\nDegree in Medicine and Surgery. University of Neaples 'Federico II”\nResident in Opthalmology. Hospital Clinico Universitario Valladolid\nMaster in Vitreo-Retina. IOBA. University of Valladolid\nFellow of the European Board of Ophthalmology. Paris\nMaster in Research in Ophthalmology. University of Valladolid\t2003-2009\n2012-2016\n2016-2017\n2016\n2012-2013\n\t\nEmployments (company and positions)\tDate (Year)\nResident in Ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl.\nFellow in Vitreo-Retina. IOBA. University of Valladolid\nVitreo-Retinal consultant in ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl. National Health System.\nVitreo-Retinal consultant in ophthalmology. Instituto Oftalmologico Recoletas. Red Hospitalaria Recoletas. \n\t2012-2016\n2016-2017\n2017-today\n\n2019-Today\n\n\n\t\nClinical Research Experience (tasks and role)\tDate (Year)\nAssociated investigator\n\n' FIS PI20/00740: DESARROLLO DE UNA CALCULADORA DE RIESGO DE\nAPARICION DE RETINOPATIA DIABETICA BASADA EN TECNICAS DE IMAGEN MULTIMODAL EN PACIENTES DIABETICOS TIPO 1. Grant by: Ministerio de Ciencia e Innovacion \n\n' (BIO/VA23/14) Estudio clínico multicéntrico y prospectivo para validar dos\nbiomarcadores ubicados en los genes p53 y MDM2 en la predicción de los resultados funcionales de la cirugía del desprendimiento de retina regmatógeno. Grant by: Gerencia Regional de Salud de la Junta de Castilla y León.\n' Estudio multicéntrico, aleatorizado, con enmascaramiento doble, en 2 grupos\nparalelos y de 52 semanas de duración para comparar la eficacia, seguridad e inmunogenicidad de SOK583A1 respecto a Eylea® en pacientes con degeneración macular neovascular asociada a la edad' (CSOK583A12301; N.EUDRA: 2019-004838-41; FASE III). Grant by Hexal AG\n\n' Estudio de fase III, aleatorizado, doble ciego, con grupos paralelos, multicéntrico para comparar la eficacia y la seguridad de QL1205 frente a Lucentis® en pacientes con degeneración macular neovascular asociada a la edad. (EUDRACT: 2018-004486-13). Grant by Qilu Pharmaceutical Co\n\n' Estudio NEUTON: Ensayo clinico en fase IV para evaluar la eficacia de aflibercept en pacientes Naive con Edema MacUlar secundario a Oclusion de Vena CenTral de la Retina (OVCR) en regimen de tratamientO iNdividualizado Treat and Extend (TAE)”, (2014-000975-21). Grant by Fundacion Retinaplus\n\n' Evaluación de la seguridad y bioactividad de anillos de tensión capsular en conejo. Proyecto Procusens. Grant by AJL, S.A.\n\n'Estudio epidemiológico, prospectivo, multicéntrico y abierto\\npara valorar la frecuencia de la conjuntivitis adenovírica diagnosticada mediante el test AdenoPlus®\\nTest en pacientes enfermos de conjuntivitis aguda”\\n. National, multicenter study. Grant by: NICOX.\n\nEuropean multicentric trial: 'Evaluation of clinical outcomes following the use of Systane Hydration in patients with dry eye”. Study Phase 4. Grant by: Alcon Labs'\n\nVLPs Injection and Activation in a Rabbit Model of Uveal Melanoma. Grant by Aura Bioscience\n\nUpdating and characterization of a rabbit model of uveal melanoma. Grant by Aura Bioscience\n\nEnsayo clínico en fase IV para evaluar las variantes genéticas de la vía del VEGF como biomarcadores de eficacia del tratamiento con aflibercept en pacientes con degeneración macular asociada a la edad (DMAE) neovascular. Estudio BIOIMAGE. IMO-AFLI-2013-01\n\nEstudio In-Eye:Ensayo clínico en fase IV, abierto, aleatorizado, de 2 brazos,\nmulticçentrico y de 12 meses de duración, para evaluar la eficacia y seguridad de un régimen de PRN flexible individualizado de 'esperar y extender' versus un régimen PRN según criterios de estabilización mediante evaluaciones mensuales de inyecciones intravítreas de ranibizumab 0,5 mg en pacientes naive con neovascularización coriodea secunaria a la degeneración macular relacionada con la edad. CP: CRFB002AES03T\n\nTREND: Estudio Fase IIIb multicéntrico, randomizado, de 12 meses de\nseguimiento con evaluador de la agudeza visual enmascarado, para evaluar la eficacia y la seguridad de ranibizumab 0.5mg en un régimen de tratar y extender comparado con un régimen mensual, en pacientes con degeneración macular neovascular asociada a la edad. CP: CRFB002A2411 Código Eudra CT:\n2013-002626-23\n\n\n\nPublications\t\n\n2021\n\n\n\n\n2015\n\n\n\n\n2021\n\n\n\n\n\n2021\n\n\n\n\n2015\n\n\n\n\n2015\n\n\n2014\n\n\n\n\n2015-16\n\n\n\n2015\n\n\n2014\n\n\n2014\n\n\n\n\n2014\n\n\n\n\n\n\n\n2014\n\nJose Carlos Pastor; Jimena Rojas; Salvador Pastor-Idoate; Salvatore Di Lauro; Lucia Gonzalez-Buendia; Santiago Delgado-Tirado. Proliferative vitreoretinopathy: A new concept of disease pathogenesis and practical\nconsequences. Progress in Retinal and Eye Research. 51, pp. 125 - 155. 03/2016. DOI: 10.1016/j.preteyeres.2015.07.005\n\n\nLabrador-Velandia S; Alonso-Alonso ML; Di Lauro S; García-Gutierrez MT; Srivastava GK; Pastor JC; Fernandez-Bueno I. Mesenchymal stem cells provide paracrine neuroprotective resources that delay degeneration of co-cultured organotypic neuroretinal cultures.Experimental Eye Research. 185, 17/05/2019. DOI: 10.1016/j.exer.2019.05.011\n\nSalvatore Di Lauro; Maria Teresa Garcia Gutierrez; Ivan Fernandez Bueno. Quantification of pigment epithelium-derived factor (PEDF) in an ex vivo coculture of retinal pigment epithelium cells and neuroretina.\nJournal of Allbiosolution. 2019. ISSN 2605-3535\n\nSonia Labrador Velandia; Salvatore Di Lauro; Alonso-Alonso ML; Tabera Bartolomé S; Srivastava GK; Pastor JC; Fernandez-Bueno I. Biocompatibility of intravitreal injection of human mesenchymal stem cells in immunocompetent rabbits. Graefe's archive for clinical and experimental ophthalmology. 256 - 1, pp. 125 - 134. 01/2018. DOI: 10.1007/s00417-017-3842-3\n\n\nSalvatore Di Lauro, David Rodriguez-Crespo, Manuel J Gayoso, Maria T Garcia-Gutierrez, J Carlos Pastor, Girish K Srivastava, Ivan Fernandez-Bueno. A novel coculture model of porcine central neuroretina explants and retinal pigment epithelium cells. Molecular Vision. 2016 - 22, pp. 243 - 253. 01/2016.\n\nSalvatore Di Lauro. Classifications for Proliferative Vitreoretinopathy ({PVR}): An Analysis of Their Use in Publications over the Last 15 Years. Journal of Ophthalmology. 2016, pp. 1 - 6. 01/2016. DOI: 10.1155/2016/7807596\n\nSalvatore Di Lauro; Rosa Maria Coco; Rosa Maria Sanabria; Enrique Rodriguez de la Rua; Jose Carlos Pastor. Loss of Visual Acuity after Successful Surgery for Macula-On Rhegmatogenous Retinal Detachment in a Prospective Multicentre Study. Journal of Ophthalmology. 2015:821864, 2015. DOI: 10.1155/2015/821864\n\nIvan Fernandez-Bueno; Salvatore Di Lauro; Ivan Alvarez; Jose Carlos Lopez; Maria Teresa Garcia-Gutierrez; Itziar Fernandez; Eva Larra; Jose Carlos Pastor. Safety and Biocompatibility of a New High-Density Polyethylene-Based\nSpherical Integrated Porous Orbital Implant: An Experimental Study in Rabbits. Journal of Ophthalmology. 2015:904096, 2015. DOI: 10.1155/2015/904096\n\nPastor JC; Pastor-Idoate S; Rodríguez-Hernandez I; Rojas J; Fernandez I; Gonzalez-Buendia L; Di Lauro S; Gonzalez-Sarmiento R. Genetics of PVR and RD. Ophthalmologica. 232 - Suppl 1, pp. 28 - 29. 2014\n\nRodriguez-Crespo D; Di Lauro S; Singh AK; Garcia-Gutierrez MT; Garrosa M; Pastor JC; Fernandez-Bueno I; Srivastava GK. Triple-layered mixed co-culture model of RPE cells with neuroretina for evaluating the neuroprotective effects of adipose-MSCs. Cell Tissue Res. 358 - 3, pp. 705 - 716. 2014.\nDOI: 10.1007/s00441-014-1987-5\n\nCarlo De Werra; Salvatore Condurro; Salvatore Tramontano; Mario Perone; Ivana Donzelli; Salvatore Di Lauro; Massimo Di Giuseppe; Rosa Di Micco; Annalisa Pascariello; Antonio Pastore; Giorgio Diamantis; Giuseppe Galloro. Hydatid disease of the liver: thirty years of surgical experience.Chirurgia italiana. 59 - 5, pp. 611 - 636.\n(Italia): 2007. ISSN 0009-4773\n\nChapters in books\n\t\n' Salvador Pastor Idoate; Salvatore Di Lauro; Jose Carlos Pastor Jimeno. PVR: Pathogenesis, Histopathology and Classification. Proliferative Vitreoretinopathy with Small Gauge Vitrectomy. Springer, 2018. ISBN 978-3-319-78445-8\nDOI: 10.1007/978-3-319-78446-5_2. \n\n' Salvatore Di Lauro; Maria Isabel Lopez Galvez. Quistes vítreos en una mujer joven. Problemas diagnósticos en patología retinocoroidea. Sociedad Española de Retina-Vitreo. 2018.\n\n' Salvatore Di Lauro; Salvador Pastor Idoate; Jose Carlos Pastor Jimeno. iOCT in PVR management. OCT Applications in Opthalmology. pp. 1 - 8. INTECH, 2018. DOI: 10.5772/intechopen.78774.\n\n' Rosa Coco Martin; Salvatore Di Lauro; Salvador Pastor Idoate; Jose Carlos Pastor. amponadores, manipuladores y tinciones en la cirugía del traumatismo ocular.Trauma Ocular. Ponencia de la SEO 2018..\n\n' LOPEZ GALVEZ; DI LAURO; CRESPO. OCT angiografia y complicaciones retinianas de la diabetes. PONENCIA SEO 2021, CAPITULO 20. (España): 2021.\n\n' Múltiples desprendimientos neurosensoriales bilaterales en paciente joven. Enfermedades Degenerativas De Retina Y Coroides. SERV 04/2016. \n' González-Buendía L; Di Lauro S; Pastor-Idoate S; Pastor Jimeno JC. Vitreorretinopatía proliferante (VRP) e inflamación: LA INFLAMACIÓN in «INMUNOMODULADORES Y ANTIINFLAMATORIOS: MÁS ALLÁ DE LOS CORTICOIDES. 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