Alessandro Di Cerbo

University of Chieti-PescaraItaly

In the last years I focused my research activity on the development of new functional foods such as probiotics, prebiotics, herbal extracts and alkylglycerols. Recently my research activity moved to the study of an old antibiotic, the oxytetracycline (OTC). I conducted data collection and analysis of clinical and in vitro studies aimed to evaluate food intolerances-related mechanisms. I also evaluated the pro-inflammatory effect of OTC and its bone-residues on cytokine secretion by human peripheral blood lymphocytes in vitro. Results showed that both OTC and OTC-bone residues significantly induced the T lymphocyte and Non-T cell secretion of Interferon (IFN)-γ, suggesting possible health risks depending on the increase of the tissues and organs inflammatory condition due to the entry of OTC in the food processing chain. This observations resulted effective in developing well balanced diets, with specific herbal extracts and selected raw materials, able to restore and maintain an overall good health status in pets and humans. At the same time I provided input to scientific manuscripts and reports contributing to the writing, coordination and management of grant application in relevant research areas. Further, from January 2016 along with researchers of the National Human Genome Research Institute (NHGRI), University of Sassari and Milan, we have sequenced the whole genome of a dog that is native to the mountains of Sardinia, Italy, and discovered in it clues about the migration of humans to the area. The findings were reported August 12, 2016 in the journal Genetics and the new spread on top sector web newspapers (Science daily, heritage daily and earth times as well as adnkronos).

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