Amperometric biosensors are widely used in point-of-care medical devices that help patients control blood glucose and cholesterol levels in an effective and convenient way. On the other hand, computer-aided technologies for biosensor design remain an actively developing field. In this chapter, we present a computational model for biosensor design that uses a reaction-diffusion equation. We have successfully applied this model to simulate cholesterol analysis based on a multienzyme system. Furthermore, we show that this computer-aided approach can be used to optimize biosensor performance. This model can be applied to industry-grade biosensor development and can be easily extended to model multiple types of biosensors for a wide array of clinical applications.
Part of the book: Computer-aided Technologies