Comparison of dimension of organizational culture.
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Barely three months into the new year and we are happy to announce a monumental milestone reached - 150 million downloads.
\n\nThis achievement solidifies IntechOpen’s place as a pioneer in Open Access publishing and the home to some of the most relevant scientific research available through Open Access.
\n\nWe are so proud to have worked with so many bright minds throughout the years who have helped us spread knowledge through the power of Open Access and we look forward to continuing to support some of the greatest thinkers of our day.
\n\nThank you for making IntechOpen your place of learning, sharing, and discovery, and here’s to 150 million more!
\n\n\n\n\n'}],latestNews:[{slug:"webinar-introduction-to-open-science-wednesday-18-may-1-pm-cest-20220518",title:"Webinar: Introduction to Open Science | Wednesday 18 May, 1 PM CEST"},{slug:"step-in-the-right-direction-intechopen-launches-a-portfolio-of-open-science-journals-20220414",title:"Step in the Right Direction: IntechOpen Launches a Portfolio of Open Science Journals"},{slug:"let-s-meet-at-london-book-fair-5-7-april-2022-olympia-london-20220321",title:"Let’s meet at London Book Fair, 5-7 April 2022, Olympia London"},{slug:"50-books-published-as-part-of-intechopen-and-knowledge-unlatched-ku-collaboration-20220316",title:"50 Books published as part of IntechOpen and Knowledge Unlatched (KU) Collaboration"},{slug:"intechopen-joins-the-united-nations-sustainable-development-goals-publishers-compact-20221702",title:"IntechOpen joins the United Nations Sustainable Development Goals Publishers Compact"},{slug:"intechopen-signs-exclusive-representation-agreement-with-lsr-libros-servicios-y-representaciones-s-a-de-c-v-20211123",title:"IntechOpen Signs Exclusive Representation Agreement with LSR Libros Servicios y Representaciones S.A. de C.V"},{slug:"intechopen-expands-partnership-with-research4life-20211110",title:"IntechOpen Expands Partnership with Research4Life"},{slug:"introducing-intechopen-book-series-a-new-publishing-format-for-oa-books-20210915",title:"Introducing IntechOpen Book Series - A New Publishing Format for OA Books"}]},book:{item:{type:"book",id:"969",leadTitle:null,fullTitle:"Lung Diseases - Selected State of the Art Reviews",title:"Lung Diseases",subtitle:"Selected State of the Art Reviews",reviewType:"peer-reviewed",abstract:"The developments in molecular medicine are transforming respiratory medicine. Leading clinicians and scientists in the world have brought their knowledge and experience in their contributions to this book. Clinicians and researchers will learn about the most recent advances in a variety of lung diseases that will better enable them to understand respiratory disorders. This treatise presents state of the art essays on airways disease, neoplastic diseases, and pediatric respiratory conditions. Additionally, aspects of immune regulation, respiratory infections, acute lung injury/ARDS, pulmonary edema, functional evaluation in respiratory disorders, and a variety of other conditions are also discussed. 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M. Irusen, FCP(SA), Pulmonology, PhD, is a principal specialist and Clinical Head of the Pulmonology and Critical Care Division of the Department of Internal Medicine, Faculty of Health Sciences, University of Stellenbosch and Tygerberg Academic Hospital in Cape Town, South Africa. He is widely published and has tremendous experience in these speciality fields.\nHis PhD training in molecular immunology and biology related to asthmatic inflammation was undertaken under the supervision of Professors Fan Chung and Peter Barnes at the Royal Brompton Hospital and the Unit of Thoracic Medicine of the National Heart and Lung Institute at Imperial College. \nHe has won numerous awards for his research, both local and international. He has served on the Council of SA Thoracic Society and is the immediate former president. 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Migration in the Last Three Centuries",subtitle:null,reviewType:"peer-reviewed",abstract:"
\r\n\tIn March 2022, another book on human migration seems important when the events or tragedies unfolding in Eastern Europe are considered. People have always migrated and have moved, but, specifically looking at the last three hundred years, involuntary migration is on the rise. Involuntary migration does not only affect Europe; Asia, Africa, and North as well as South America, have had their fair share of natural catastrophes, invasions, and wars.
\r\n\tThis book will intend to look at different migrant patterns, voluntary and involuntary migration, over the last three centuries. What influenced people to leave their home countries, family, and friends and settle somewhere else? The book may include histories of the 19th century, consider tragedies and movements activated by political events in the 20th century, and/or look at recent events of the 21st century. Push and pull factors are important points. While most of us may be influenced in a negative way by the current happenings in Eastern Europe, the Russian invasion and resulting tragedies also demonstrate some very positive human traits – the preparedness of Ukraine’s surrounding countries to help those in need and to provide a safe place for the present.
\r\n\tWhether one looks at voluntary or involuntary migration into any country, after a period of adjustment, migrants do play a positive role. The research found that migrants contribute to the economy (food, shelter, employment, tax) and enrich a country’s cultural norms. Prerequisites for successful settlements are that the host society adopts a tolerant approach and that the migrants recognize the law and the language of the host country. Nothing is ever easy or without controversy, but I am a migrant (German Australian), and life in Australia has been relatively harmonious. Issues that could be considered in the book are multicultural societies (do monocultural societies still exist?) and theories of acculturation versus integration (settlement processes).
\r\n\tTwo further issues are very important in relation to human migration. There is climate change, global warming, and the environment, which clearly affect people’s movement. Small island populations are very concerned about rising sea levels. 2021 has also seen floods costing human lives: Turkey (August 2021), Brazil (December 2021), Chile (January 2021), and South India (November 2021), to name but a few. In Australia (March 2022), farms and whole townships in New South Wales and Queensland have been flooded for the second time in five years, and plans to resettle these towns are considered. Official and social media provide ample coverage of the events, which leads me to the next issue. There is today’s very important role of the media, of the official and social media. We are constantly bombarded with images of human war tragedies and flood victims. People in industrialized, western countries must be the best-informed populace. How far do the images and up-to-date TV news influence us, make us change our behavior, and perhaps even consider us more generous than we have been?
\r\n\tClimate change and the media are relatively new to the human migration debate, but both issues play important parts, and some interesting discussions are appreciated.
\r\n\t
It is a legal requirement that employers must provide a safe and healthy working environment their employees. In terms of public health, it is important to control occupational and environmental factors in all workplaces [1]. Health sector is one of the dangerous lines of work in which occupational health and safety (OHS) are becoming increasingly important. Healthcare professionals are faced with many occupational risks while performing their duties. There are also many risk factors for those who work in operating rooms. These include inconvenient physical environment, heavy physical work, working in shifts and working in non-ergonomic positions [2, 3, 4, 5]. Employee health is also threatened by stress, mobbing, violence, malnutrition etc. For example, being in close contact with the patient in the operating room increases the risk of infection. Nurses who are likely to come into contact with blood and bodily fluids of the patients during their daily activities at the hospital are in the high risk group for blood-borne diseases. Thus, researches indicate that nurses are mostly faced with biological and psychological risk factors [6]. Operating room employees may experience occupational accidents due to sharp object injuries, contamination with blood and bodily fluids, heavy lifting, falling, hitting, tripping, slipping, being injured etc. [7, 8]. Moreover, traffic accidents during commute and all kinds of accidents that happen at work such as musculoskeletal system wounds, violence, allergic reactions, burnt, poisoning, fire, explosion and electric shock can also be listed among these [9].
However, the duties of healthcare professionals are mostly considered as providing service to patients who need healthcare. Therefore, it is mostly neglected that healthcare professionals can have occupational problems. In this respect, institutions that provide healthcare service are generally organized to achieve patient care, treatment and satisfaction instead of prioritizing the health and safety needs of healthcare personnel. Work environment, occupational health and safety of the healthcare professionals, who provide service for patients, are mostly overlooked.
The risks of the operating rooms may cause a decrease in productivity, economic loss of the institution, increase in occupational accidents, and putting the people who receive care from healthcare professionals directly at risk. Therefore, hospitals need to be suitable for health and safety measures, environmental precautions should be taken, risk factors should be eliminated or controlled and personal protective equipment should be paid attention to by performing risk assessment and management.
Physical factors take an important place in healthcare institutions. Primary physical factors affecting work in operating rooms can be listed as temperature, noise, lighting, humidity, air-conditioning, air pollutants, ionizing radiation, non-ergonomic work conditions etc. [10].
Work environment should be adequately lighted in order for the healthcare personnel to do their jobs properly and comfortably. Especially in working areas critical for human health such as operating rooms, inadequate lighting negatively affects the personnel’s vision and excessive lighting can cause personnel to get exhausted. Researches show that light and electromagnetic fields affect the function of pineal gland. In the long term, this may lead to problems in reproductive functions, depression and especially breast cancer in women. Exposure to light at night or electromagnetic fields decreases the melatonin production of pineal gland which increases the production of estrogen from the ovaries and may cause malignant transformation in breast epithelial cells. Therefore, lighting in healthcare institutions is important especially for those who work in shifts, have night shifts and work at intensive care units.
Operating rooms are desired to be quiet environments. Sound level should not exceed 35–40 decibels in the units where patients are lying. However, it can be noisy during patient visit hours, crowded polyclinic hours and some operations. It is observed that sound level in the operating rooms reaches maximum especially during the preparation to the operation and using the surgical tools during the operation [11]. A study by Juang et al. states that physiological states of the nurses working at intensive care units for over five years are severely affected [12]. It is also stated that these nurses, especially the ones working in different shifts, are extremely sensitive to noise and cannot tolerate it. Varicose vein, the main risk factor of which is to stand still, is seen very often especially in nurses working in operating rooms.
Sharp object injuries, which are generally preventable risk factors for nurses, are mainly caused by tools that disrupt skin integrity. Inadequate number of nurses in operating rooms, shifts, high work circulation, and long working hours also increase the risk of sharp object injuries. Because more risky surgical tools are used in these units besides the tools used by other healthcare personnel. Operating rooms have a risk of fire due to factors such as use of lasers and oxygen. Heating flammable preparation materials pose a serious risk for fire. These agents can easily catch fire with increased temperature. If a flammable preparation material is being used, additional precautions should be taken to avoid surgical fires and burns in patients. Operating room staff should have sufficient knowledge on laser and oxygen use, factors causing fire and how to use fire extinguishers.
Surgical site infections are one of the most difficult postoperative complications which threaten millions of lives every year. Current evidence presents a positive relationship between the infection rate and the concentration of the bacteria-carrying particles in air [13]. Ventilation of the operating room is important to decrease the concentration of bacterial pollutants in air and control the risk of infection. Advanced air conditioning systems are needed to minimize the risk of infection and keep the concentration of microorganisms at the minimum values specified by standards. To that end, ventilation systems of operating rooms should be designed and organized in a way to prevent occupational and healthcare institution originated infections by considering the biological and physical characteristics of the microorganisms.
Air conditioning installation should be performed in frequent intervals determined by laws and elaborately controlled in order to minimize the microorganisms, dust, narcotic gases and bad odors in the hospital, as well as providing comfort conditions in the operating rooms. Inadequate or improper ventilation may cause health problems and employees to breathe more air pollutants.
Various chemical substances are used in operating rooms to provide healthcare service. These substances are especially used to take hygienic precautions as well as diagnosis and treatment. Healthcare professionals can get exposed to the chemical substances in various ways such as respiratory system, gastrointestinal tract, absorption (skin, eyes) and pinpricks. These chemical substances have acute or chronic effects on healthcare personnel [14, 15]. Effects of chemical substances on healthcare personnel may vary according to duration of contact, way of contact, physical and chemical characteristics of the substance. The effectiveness of the substance can especially vary by the presence of different chemical substances in the work environment, genetic and personal characteristics of the employee and addictions such as alcohol and smoking.
Disinfectants, anesthetic agents, cytotoxic agents, drugs, some heavy metals such as mercury and latex are primary chemicals used in operating rooms [16]. Glutaraldehyde, formaldehyde, ethylene oxide are commonly used in operating rooms for chemical sterilization. Some of them, for example alcohol, have a relatively low toxicity. On the other hand, glutaraldehyde and formaldehyde are extremely irritant for skin, eyes and airways even at very low concentrations and their increased concentrations may result in increased heart rate and pulmonary edema. Formaldehyde belongs to “Group-1 Carcinogenic to humans”, which includes factors proven to cause cancer by International Agency for Research on Cancer [17]. Ethylene oxide, used for the sterilization of heat sensitive materials, shows mutagenic and carcinogenic characteristics as well as toxic and explosive effects. Ethylene oxide is a combustible gas which explodes when it reaches %3 concentration. Its acute effects are respiratory problems and neurological symptoms. High level of exposure causes cataract. Moreover, the need for a relatively long time for sterilization causes the risk factors to extend over time. Nurses can be exposed to risk while they break the ampoule containing the medicine, dilute the medicine in powder form, spilling the medicine by accident etc. Allergic reactions in nurses working in operating rooms mostly develop as latex energy due to frequent use of gloves. Latex gloves are flexible, easy to wear and used for every process in the operating room. Latex can cause allergic reactions ranging from mild contact dermatitis to urticaria, conjunctivitis, bronchospasm and anaphylactic shock.
Anesthetic gases take an important place in chemical risks that healthcare professionals are exposed to [18]. Operating room is constantly contaminated by the leakage from the valves of anesthetic devices and even by the anesthetic gases of the expiratory air of the patients. Healthcare professionals are chronically exposed to these gases in operating rooms. Anesthetic gases are highly volatile compounds and especially small indoor places such as operating rooms can get highly contaminated with these gases in a short amount of time. Anesthetic gases can affect employees in the operating room and recovery room [19]. Anesthetic gases spread in a way that harms the environment by leakage from the anesthetic devices, accidental spilling and spreading of the gas, using an unsuitable mask on the patient, poorly inflating the intubation tube and the gas spread by the expiration of the patient. Epidemiological studies show that chronic exposure to anesthetic gases is an occupational risk which has consequences like spontaneous abortion, congenital malformations, premature birth, cancer, liver and kidney diseases, regression in mental functions, headache, fatigue and irritability [20]. Therefore, nurses working in operating rooms, surgical doctors and other personnel working in operating rooms are at high risk of anesthetic gases (nitrous oxide, halothane, isoflurane etc.)
On the other hand, healthcare personnel may be exposed to chemical substances in the hazardous medicine during the preparation, transfer, application, storage and disposal of the medicine. Cytotoxic drugs have the potential to cause serious health problems for people and personnel who come into contact with them. The risks include cancer, malformed, abnormal birth, recurring toxic effects, organ or tissue damage, chromosomal abnormalities. More women are employed in healthcare sector compared to other sectors and majority of the chemically risky actions are performed by nurses, the majority of whom are women. Therefore, another dimension of the danger of the chemical substances is that most of these substances have genotoxic effects (mutagenic, carcinogenic and/or teratogenic) and they may cause spontaneous abortions, low birth weight, babies with anomalies by affecting the reproductive health of the women working in operating rooms.
Healthcare employees are at risk of various infectious diseases at the daily work environment. Thousands of healthcare employees are caught in numerous serious infections such as Hepatitis B, Hepatitis C and AIDS. Respiratory transmitted diseases, which are among the occupational risks for employees in healthcare sector, are huge reasons of loss of work and power. There are two main ways for respiratory transmission which are droplet contact and airborne transmission. Droplet contact refers to contact of the droplets carrying microorganisms from an infected person to conjunctiva, nasal or oral mucosa (by coughing, sneezing, speaking, bronchoscopy or aspiration). Airborne transmission refers to the spread of the droplets carrying microorganisms through air by suspending in air for a long time or contacting dust particles.
A newly identified coronavirus, SARS-CoV-2, has caused a worldwide pandemic. Coronavirus was first identified in December 2019 in China. In February 2020, the World Health Organization (WHO) named it COVID-19. Covid-19 with high transmission level, it has become a serious public health issue. COVID-19 easily is transmitted by respiratory system which causes numerous deaths and it is a serious threat for healthcare professionals. Nurses should act carefully to protect both themselves and the patients from contamination in operating rooms. Personal Protective Equipment (PPE) should be used in accordance with the rules. Surgical nurses should carry out this challenging process with a multidisciplinary approach in issues such as restructuring in operating rooms and reviewing in-hospital triage [21, 22, 23, 24]. Surgical smoke may be effective in the spread of coronavirus [25]. Surgical smoke is a potential risk factor for patients, personnel and environment. Mutagen gases, carcinogens, particles containing DNA components or HPV (Human Papilloma Virus) may spread in air via smoke when lasers or electrocauteries are used [26, 27].
Nosocomial infection occurs when pathogens are transmitted by nurses and healthcare personnel who came into contact with intubated patients in intensive care units and patients with intravascular catheters. Nosocomial infections emerge as direct or indirect microbial spread (cross infection) or spread from one’s own infected tissue to another tissue (self-infection). Studies show that nosocomial infections are mostly caused by microorganisms in the environment outside of patient and healthcare employees are the primary source of infections. Both the bacteria found in these individuals and the ones that are transmitted to other patients are important sources of nosocomial infections.
Studies on infection prevalence and risk analysis are increasing and new information is obtained day by day. Another of these infections is blood-borne infections [28, 29, 30]. Blood-borne infections are of particular importance because of their frequency and long term negative effects. Serious precautions should be taken to protect healthcare professionals from blood-borne infections. Personnel at risk should be included in vaccination program. Hygiene is very important. The labels of bags and containers used to transport waste with risk of contamination should be colored in red and clearly indicate danger. Sharp and penetrating tools should be carried in labeled, special containers in conformity with the standard. There should be no risk of contamination or leakage in these containers. Contaminated laundry should be carries in special, marked bags which should be labeled as dangerous. The use of gloves is very important. Biological risk factors can be controlled as well as employee safety if risk factors are known by all employees and necessary precautions are taken.
Nurses have a very active role in every field of healthcare service present in operating rooms. Nurses are under more pressure and experience more psychological reactions due to the occupational differences in working conditions [31, 32, 33, 34]. Therefore, more satisfied, happier and more productive nurses are important to increase the quality of the service provided. However, job satisfaction of nurses can be negatively affected by hopeless thoughts on the future of occupation, the fact that nursing is considered as an auxiliary occupation and difficult work conditions, which is the foremost problem in nursing. Nurses need to work in shifts since healthcare institutions provide service for 24 hours. This may have negative effects on the biological, psychological and social lives of nurses. Working in shifts disrupts body’s normal biological rhythm and may cause chronic fatigue and disruption in person’s family and social lives. The fact that nurses have to work at nights and on the weekends besides the traditional working hours is a cause of stress on its own. Nurses may have problems in communication due to the way they work. Moreover, reversed biological clock may cause chronic fatigue, tiredness and depression. Overtime work causes a decrease in attention level in operating rooms where attention is very important and this causes an increase in the possibility of making mistakes and decrease in the quality of work. Therefore, operating room nurses experience stress and homeostatic deterioration comes with sleep disorders and have significant effects on the quantity of life and performance of people.
Surgical teams in the operating rooms generally differ by the type of operation. However, anesthetic team generally remains constant and works longer times in shifts. Thus, health problems are more common in this group.
Workplace violence is the most common situation that healthcare professionals encounter. Violence against doctors and healthcare personnel have been rapidly increasing in recent years. Healthcare employees are a specific group in terms of facing stress and exposure to violence is quite high in this group. There many different factors of violence such as patients, relatives, coworkers in healthcare institutions. Hospitals are becoming more dangerous for healthcare personnel day by day [35]. In that case doctors and healthcare personnel do not feel safe themselves in their workplaces. In a Turkish study by Ayranci et al., on healthcare professionals, it was identified that 50.8% of the healthcare professionals were subjected to one or more type of violence while they were working, practitioners were subjected to violence the most (67.6%) and 58.4% of the nurses were subjected to violence [36]. A research in Turkey by Gokce and Dundar on doctors and nurses stated that 71.4% of the doctors and 90% of the nurses were subjected to violence [37].
Healthcare professionals try to do their best in their jobs, just like the employees in other sectors. In order for healthcare personnel to efficiently perform what is expected from them, work environment should be designed in a way that allows moving comfortably. Ergonomics refers to designing and organizing the workplace and equipment in the most physically suitable way for the users. No matter how perfect they are technically, if the tools and equipment, tables, chairs and methods used by healthcare personnel are not suitable for themselves, a high performance should not be expected. In other words, if they are designed without considering the characteristics, abilities and disabilities of the people, employees cannot perform with high performance. Ergonomic stress factors are very common in operating rooms. Especially the nurses who provide service to the complete dependent patients help them with all activities such as getting dressed, eating, going to bathroom etc. This may cause musculoskeletal injuries, especially due to overload, in healthcare personnel. Researches on nurses identified that bad back problems are more common in nurses compared to the people working in fields requiring heavy physical work. Hospital employees are in the risk group for backache; occupational activities such as lifting patients in improper positions, leaning forward, turning around and standing still for a long time may cause biomechanical stress in vertebra and backache [38, 39, 40, 41].
Another important risk factor in hospitals is radiation. Regulations on this subject must be followed carefully [42, 43, 44, 45]. Radiation in operating rooms can be emitted from mobile rontgen devices, fluoroscopy devices and non-ionizing devices like lasers [46]. Radiation exposure is caused by working with fluoroscopy and radioactive substance application in operating rooms. Long term effects of low dose radiation use for a long time in operating rooms are not known. Biological effects of the ionizing radiation in the tissue differ by the total dose, dose rate, amount of body receiving radiation, radio sensitivity and the type of radiation and it may have stochastic and deterministic (non-stochastic) effects. Adverse effects of radiation exposure can occur within hours or years. Thyroids, eyes, hands and gonads are among the regions that are most affected by radiation. Radiation safety is important for employee safety as it is for patient safety. In studies conducted on operating room workers, it was determined that healthcare workers ignored protective measures regarding radiation safety [47, 48, 49]. The main reason for this was explained by the lack of knowledge of the employees on the physical characteristics and biological effects of radiation. Yet, setting and applying basic principles of radiation protection is important for employee and patient safety. Therefore, attention should be paid for in-service trainings for operating room personnel, inspection of the application and having informed and certified personnel to use fluoroscopy.
OHS aims to minimize occupational accidents and diseases and to keep the health of employees at the best level in all the world. With OHS studies, dangers and risk factors should be determined and controlled at their source. Operating rooms are complex places where the most advanced technology and systems are used and qualified employees work at. The most threatening factors for employee safety in operating rooms are contaminated, sharp object injuries and material splashes. The most common ones are pinprick injuries. Allergies to latex gloves and hand washing solutions in the operating rooms may cause serious problems. Ergonomics is an important yet ignored topic. If the actions such as positioning and lifting patients, transferring patients from the bed to the stretcher and carrying patients are performed without being careful, they may cause serious musculoskeletal problems for employees. Factors such as excessive amount of time spent in work environment, shifts and insufficient number of nurses may cause an increase in work intensity and a decrease in motivation for nurses.
Critical decisions on the lives of patients are taken and applied in operating rooms which have high level of psychological and physical stress. Therefore, they require concordant team work and moderate work environment. Use of too many technological devices, necessity to make fast decisions and risks caused by the nature of the operating rooms also pose some risks for the employees. Nurses working in operating rooms may encounter various risky conditions as explained above. Unsuitable physical environment, heavy physical work, frequent criminal activities, working late at night with fewer people, working in non-physiological positions, non-ergonomic conditions, stress, discomfort, workplace conditions which makes healthy diet difficult, commute problems are factors threatening employee safety. Since numerous factors might have negative effects on the safety and health in operating rooms, risk assessment should be performed and reformative-preventive actions should be taken in order to identify characteristics such as what these factors are, at what level they are present and who they affect. Occupational health problems caused by the risks in the workplace can be reduced and the rates of serious injuries and damages can be decreased with proper and efficient risk management.
Operating room nurses should be trained on subjects such as general environmental pathogens, ergonomics, blood-borne pathogens, protective equipment, radiation safety, fire safety, general safety, use of hazardous material (substances), emergency situation management, protection against airborne diseases, mobile liquefied oxygen, communication and enlightenment on dangers, medical equipment care and safety of tap water.
Primary precautions to reduce exposure to chemical substances include using materials with low danger potential, paying attention to the allowed concentrations, frequently ventilating the environment, hand washing, using personal protective equipment such as aprons and masks, updating old methods and equipment, measuring and monitoring samples taken regularly, biological monitoring. In addition to these, there are many precautions that are customized according to the characteristics and risks of the chemical substances.
Preoperative, intraoperative and postoperative management of the patients with suspected or diagnosed new coronavirus pneumonia should be known and defined in detail. All healthcare professionals, particularly surgeons and nurses, should be provided with advantages in protection from the disease. All patients should be managed as Covid-19 patients until the results are confirmed. Risk of Covid-19 should be considered for general surgery emergencies and personal protective equipment should be used accordingly. Patients should be transferred to the operating rooms by service nurses and nurses should wear N95 masks, goggles/face shields, waterproof aprons and overshoes. Patients should also wear a surgical mask and transferred to the operating room via the shortest way with least contact with others.
Hospital management should take precautions against the risk of infection, nurses should gain more awareness and pay attention to using protective equipment such as gloves and masks. Ventilation of the healthcare institutions is important to protect patients and healthcare personnel and to prevent the infections caused by the institution. For this purpose, various air conditioning systems are developed, each of which has its pros and cons. It is thought that improving environmental conditions of the operating rooms would increase the chance of preventing surgical infections, decrease complications, increase the quality of the operation, increase the quality of healthcare service by decreasing cost and reduce the stress of the operating room personnel.
Multidimensionality of the concept of health and the need for interdisciplinary cooperation and several approaches are some of the most important elements that form the basis of nursing education. Nurses who are educated on occupational risks and employee safety can have the ability to define and control the possible risk factors. Nurses undertake many duties besides patient care in operating rooms, which are not their essential duties. Excessive workload and transfer of the duties of other disciplines to nurses leads to the emergence of an unhappy occupational group which works hard yet does not have time to practice their own profession. This situation should be prevented and it should be ensured that nurses do the duties they have been trained for.
Concordance and productivity of the team depend on the position and role of each member of the team being defined and recognized. It also depends on each member having the capability and possibility to perform their own roles at their best. Therefore, nurses’ roles should be defined and nurses should be capable of performing those, and roles of nurses should be known, recognized, accepted and respected by the other members of the team. In order to establish such an environment, besides following the law and legislation, employees and employers should accept their roles that prioritize health and safety, believe that safety would be maintained in the institution, adopt an appropriate attitude and display social responsibilities.
As described above safe working environment is important for all hospital workers, especially for those who work in operating rooms. Necessary precautions should be taken and controlled regularly in order for surgical nurses to perform their duties successfully. Employees should be informed about work safety precautions and most importantly push for these precautions. In addition to patient and employee safety in operating rooms, environmental safety also has an important place. Environmental risk analysis should be performed by experts in the operating rooms at regular intervals and risk management should be implemented by the occupational health and safety committees in the hospital.
The author declares no conflict of interest.
Culture in public sector organizations varies in its dimensions. Organizations comprise people. People are divided into nation-states and are variably exposed to different things such as events and information, which help form their own beliefs, values, and attitudes. These differences in beliefs, values, and attitudes result in different cultural practices, which in turn get a reflection in the organizations of their respective societies. Within a society, different subgroups exist with distinct beliefs and practices. The different generational cohorts within a society become exposed to things, technologies, and events that are particular to their own time. Therefore, subgroups within a society develop thinking and behaviors that may be considered distinct. The societal general culture and subcultures affect the cultural beliefs and practices of the organizations of society.
It is generally taken for granted that culture motivates the employees of an organization to behave in a particular way. Not much research is done on how culture affects the performance of organizations. The limited number of studies investigating the cultural influence on performance reports the linkage to be positive [1, 2]. In some other contexts, despite deliberate efforts, in the public sector, organizations have shown indifference to the adoption of the prescribed culture [3]. In spite of the influences from the new public management tools, public sector organizations tend to be internal-oriented rather than being external-oriented [4]. Organizations can develop the practice of subculture, which can be considered a management technique [2, 5].
This chapter focuses on the cultural practices of the frontline bureaucrats in Bangladesh. The few studies conducted on the bureaucratic culture in Bangladesh are different from the current one in their focuses and methodologies. Jamil [6] conducted a survey in December 1992 and January 1993 on 161 bureaucrats working in both the central level administration and the field level administration and found that the bureaucrats inculcate power distance, uncertainty avoidance tendency, and are less participatory in their decision-making process. Haque and Mohammad [7], analyzing the historical accounts, relevant literature, and their observations, concluded that the prevalence of pervasive corruption in the Bangladeshi bureaucracy could be explained in terms of the existence of some culture dimensions in the public administration. Conducting 40 qualitative semi-structured interviews with bureaucrats from the central and field administration, Rahman [8] found that the bureaucrats suffer from indecision over maintaining political neutrality and political responsiveness. Zafarullah [9] found in his study of bureaucratic culture in Bangladesh that the bureaucrats support clientelism and self-preservation and oppose change initiatives. Based on personal experience and review of literature, Rashid [10] concluded that bureaucrats had less engagement with members of the civil society and non-government organizations.
The above studies had a limitation in terms of their sample size and sampling process. This study covered a larger sample chosen from the field administration only. It investigated how four dimensions of organizational culture were practiced by the frontline bureaucrats. There are two broad types of bureaucrats in the public services of the country—cadre services and non-cadre services. Recruitment, training, and mobility of the bureaucrats of these two categories are different. Therefore, how the two groups of frontline bureaucrats differ in practicing culture dimensions of power distance, uncertainty avoidance, participation, and team orientation had remained unexplored, and this has been the main objective of this study. The second section discusses how organizational culture is understood, followed by a discussion on culture dimensions in the third section. The fourth section discusses the relevance of the four dimensions of organizational culture to frontline bureaucracies, followed by a short section introducing frontline bureaucrats in Bangladesh in the fifth section. The sixth and seventh sections discuss the methods followed and the findings of the study, respectively. The last two sections present a discussion on the findings and conclusion of the study.
Hofstede, Hofstede, and Minkov [11] described culture as a “mental programming” or “software of the mind.” It is shared patterns of thinking, feeling, and acting. Therefore, it is always a collective phenomenon. The patterns of thinking, feeling, and acting differentiate one group of people from others. Thus, culture is “the collective programming of the mind that distinguishes the members of one group or category of people from others” ([11] p. 6). The patterns of thinking, feeling, and acting come from the unwritten rules of the social game. The understanding of culture given by Hofstede et al. [11] is similar to that of Pettigrew ([12], p. 574), who defined it as a “system of such publicly and collectively accepted meanings operating for a given group at a given time” and provides “a general sense of orientation” to the group.
O’Reilly, Chatman, and Caldwell [13] have argued that organizational culture as a concept has a long history and goes back to early sociological studies of the early 1950s. It received prominence in the 1980s. Hofstede, Neuijen, Ohayv, and Sanders [14] found no consensus on the definition of the concept. However, they identified several characteristics of organizational culture. Organizational culture is: (1) holistic, (2) historically determined, (3) related to anthropological concepts, (4) socially constructed, (5) soft, and (6) difficult to change. Schein ([15], p. 111) published an article defining organizational culture as “(1) a pattern of basic assumptions, (2) invented, discovered, developed by a given group, (3) as it learns to cope with its problems of external adaptation and internal integration, (4) that has worked well enough to be considered valid and, therefore (5) is to be taught to new members as the (6) correct way to perceive, think, and feel in relation to these problems.” Schein [15] identified three levels of organizational culture: (1) artifacts, (2) values, and (3) assumptions. However, Hofstede et al. [14], in their study, found that shared perceptions of daily practices rather than shared values represent the core of an organization’s culture.
Organizational culture has also been described as an administrative culture or bureaucratic culture or corporate culture. Jamil [6] argued that there is something additional in an administrative culture than can be found in organizational culture. This additional item is politics. Most culture studies focus on the private organization where politics is not an issue of interest. These studies look at the internal context of an organization. Any framework for understanding administrative culture has to incorporate politics, i.e. how bureaucrats interact with politics and society as a whole. Jamil’s [6] arguments obtain strength from the fact that the mission of public sector organizations significantly differs from that of private sector organizations. Most public sector organizations are not profit-making and do not rely on profits for their existence.
In contrast, private sector organizations are profit-oriented and rely on profits for their existence. Public sector organizations cannot avoid politics because they execute the government’s policies. There is a subtle nuance between the usages of the concepts of “bureaucratic culture” and “corporate culture.” The concept of bureaucratic culture refers to the values and practices in public sector organizations, while corporate culture usually refers to private sector organizations.
Whatever the characteristics or levels of organizational culture are, it is a “powerful force” in an organization [3] and immensely affects the well-being and success of an organization. It is described as the glue that holds the organization together [16]. The culture encourages the members in the organization to behave similarly. It impacts how well the organization will function. Rong and Hongwei [17] argue that organizational culture stems from the social culture and works as an “invisible hand” in public sector management. This hand is relatively stable but transforms itself in the long run in line with social change.
Lloyd [18] found that there are debates about what organizational culture is. Some believe it as what an organization “is” and others believe that it is what an organization “has.” However, both arguments converge in the belief that culture is something to be made up of such concepts as beliefs, assumptions, and values. Values have received prominence in the definitions of organizational culture. Values are defined as a criterion using which one tends to prefer certain states of affairs over others. Beliefs are something that one considers as truth. The learned linkage between beliefs and values becomes attitudes. When the values, beliefs, and attitudes become so entrenched in an organization that they are no longer doubted or debated, they become assumptions. These values, beliefs, and assumptions are shared among the members of the organizations. Hofstede et al. [14] in a cross-organization study of 20 organizations in two countries found that practices rather than values play a major role. Organizational cultures are acquired on the job and are exchangeable when one takes a new job. While social cultures reside in values, organizational cultures reside in practices. These practices are visible and consciously carried out.
Organizational culture is not a one-dimensional concept. Culture researchers have found different dimensions in organizational culture. Hofstede et al. [14] in their cross-organization study have identified six dimensions of organizational culture with respect to the practices where organizations differ. These dimensions are (1) process orientation vs. results orientation, (2) employee orientation vs. job orientation, (3) parochialism vs. professionalism, (4) open system vs. closed system, (5) loose control vs. tight control, and (6) normative vs. pragmatic. They argue that these dimensions may not be universally valid or sufficient. Organizational cultures in different contexts may require additional dimensions or some of the identified six dimensions may seem less useful. Along with these six practice dimensions of organizational culture, they also identified three value dimensions, which are (1) the need for security (uncertainty avoidance), (2) work centrality (job involvement), and (3) the need for authority (power distance).
The first practice dimension of organizational culture in Hofstede et al.’s [14] study opposes a concern for means to a concern for goals. They equate this contrast with the distinction made between the mechanistic and organic management systems of Burns and Stalker [19]. With a process or mechanistic orientation, an organization tends to focus on technical improvements of means rather than the accomplishment of ends. An organic system tends to focus on concern as a whole. The second practice dimension opposes concern for the employees to concern for the job to be done. In the third practice dimension, a contrast is made between the identification of the employees deriving from the organization (parochial) and the type of job (professionalism). The fourth dimension focuses on the tendency of the organization to respond to its environment. The fifth practice dimension shows the contrasts in the internal structuring of an organization. The sixth practice dimension shows how an organization is oriented toward its customers. A normative organization looks at its task toward its customers as the implementation of inviolable rules. A pragmatic organization tends to stay close to its customers. The authors distinguish results orientation from customer orientation in that “trying to serve the customer does not automatically imply a results orientation” ([14], p. 304).
Ghosh and Srivastava [20] noted that the concept of organizational culture has been interpreted differently and not all complement or converge. After reviewing a sample of the literature on the instruments used in survey studies of organizational culture, the authors concluded that no two instruments were alike, and no two instruments shared a common theoretical basis. These authors reported that Ashkanasy, Wilderom, and Peterson [21] and Wilderom, Glunk, and Maslowski [22] had studied 18 culture measure questionnaires published between 1975 and 1992 and 10 empirical culture research studies respectively. Both studies found great variation in the definition and operationalization of organizational culture and its dimensions.
Ghosh and Srivastava [20], based on Kluckhohn and Strodtbeck’s [23] model, identified seven dimensions of organizational culture: (1) participation, (2) respect for individual, (3) attitude to risk, (4) attention orientation, (5) trust, (6) openness, and (7) power distance. Schein [15] in attempting to understand the content of a culture identifies some of its dimensions and presents questions to be asked regarding each dimension. Answers to these questions will identify the content of that culture, but he cautions about the danger of over-generalizing the dimensions.
Harrison and Baird [3] compared the organizational culture of public sector organizations in Australia with that of private sector organizations using O’Reilly et al.’s [13] organizational culture profile (OCP) and by focusing on five dimensions: (1) outcome orientation, (2) respect for people, (3) attention to detail, (4) team orientation, and (5) innovation. O’Reilly et al. [13] developed the OCP in order to quantitatively assess organizational culture in their study examining the person-culture fit and its implications for work attitudes and behaviors. These researchers carried out two types of factor analyses—for the individual and as organizational profiles. The first analysis produced eight dimensions of an organization’s culture: (1) innovation and risk-taking, (2) attention to detail, (3) orientation toward outcome or results, (4) aggressiveness and competitiveness, (5) supportiveness, (6) emphasis on growth and rewards, (7) a collaborative and team orientation, and (8) decisiveness. The second analysis produced seven dimensions: (1) innovation, (2) stability, (3) respect for people, (4) outcome orientation, (5) attention to detail, (6) team orientation, and (7) aggressiveness. Denison and Mishra [1] used four organizational traits—involvement, adaptability, consistency, and mission—in their research to determine the relationship between organizational culture and organizational performance.
Jamil [6] studied bureaucratic culture in the context of Bangladesh in order to determine the dominant type of culture and its consequences and also to identify the bearers of administrative subcultures. He noted that most studies on organizational culture have dealt with private sector organizations. He argued that public sector organizations are different from the private sector ones in that politics play a major role in the public sector organizations. Any study about public sector organizational culture has to take into account its external context, that is, its relationship with politics and the society in general.
Jamil [6] argued that bureaucrats’ attitudes in the external context could be typified in terms of their relationships to politics and relationships to citizens and civil society. In the case of the first typology, Jamil [6] argued, borrowing from Putnam [24], that bureaucrats can be classified into classical or political. Classical bureaucrats are procedure-oriented or rule-oriented, whereas political bureaucrats are problem-oriented or program-oriented. In the case of the second typology, bureaucrats can be universal or clientelistic. Universal bureaucrats believe in impartial applications of rules, which in Weberian terms are called the rational-legal type. Clientelism, on the other hand, serves in return for patronage and a power base. A recent development in the bureaucrat-citizen relationship has revealed that citizens are considered as customers in Western nations and as subjects in developing countries.
In the internal context, bureaucrats’ attitudes, Jamil [6] continued, can vary in specific characteristics such as power distance, uncertainty avoidance, guiding decision-making, and preferred employees. Power distance is a character that affects the decision-making behavior of bureaucrats. Where power distance is high, top bureaucrats take decisions, and lower bureaucrats carry out them. Where power distance is low, superiors and subordinates make consultations to take decisions.
According to Jamil [6], uncertainty avoidance is another character that affects decision-making behavior as well. Bureaucrats with a high tendency toward uncertainty avoidance tend to follow the rules and regulations strictly and do not take risks. Contrarily, a low tendency toward uncertainty avoidance encourages them to take risks in terms of bending or breaking the rules.
Bureaucrats need information for making decisions. Jamil [6] argued that the nature of the decision-making structure affects information search behavior. A top-down or hierarchic type of decision-making structure leads bureaucrats to limit their information search within its boundaries, their superiors, colleagues, or juniors. However, a collegial structure of decision-making leads bureaucrats to search beyond its boundaries, that is, politicians; citizens; academic, economic, and voluntary organizations.
Another characteristic of bureaucratic decision-making, where bureaucrats differ in their attitudes, Jamil [6] argued, is preferred employees. The attribute of preferred employees argues that the employees for an organization should be chosen considering their social values and cultural characteristics. The social values and the cultural characteristics of the chosen employees should benefit the organization.
A comparison of the dimensions of the organizational culture identified by the different studies is presented in Table 1. It reveals that scholars do not agree in identifying common cultural dimensions. However, some of them agree with some of the dimensions. Some other dimensions are given different names by different authors.
Frontline bureaucracies—also known as street-level bureaucracies—are located at the bottom of the governmental pyramid. The citizens experience their government through the frontline bureaucracies because these are the service providing windows of the government. Therefore, the cultural practice of the frontline bureaucrats is of paramount importance to the government. Alom [26] identified four culture dimensions that affect transparency and accountability behaviors of the frontline bureaucrats. These culture dimensions are power distance, uncertainty avoidance tendency, participation, and team orientation. One of the critical features of good governance is accountability, which comes through transparency. In this sense, the four culture dimensions affect good governance the most.
Most frontline bureaucracies bear two common characteristics—they enjoy discretion but suffer from resources. The resource limitation characteristic may vary from context to context based on economic development of the countries, but discretion has been reported to exist irrespective of the level of economic development. Discretion is a structural feature, while resources are issues of an endowment. Therefore, these are not cultural factors. However, these factors in interaction with the cultural beliefs and practices—power distance, uncertainty avoidance, participation, and team orientation—may impact on the good governance practices of the frontline bureaucrats. A brief discussion of these four cultural beliefs and practices is given below.
The frontline public bureaucracy in Bangladesh represents the characteristics of the overall public service of the country. These characteristics descended from the British colonial administration and the post-colonial administration of Pakistan. Bangladesh was liberated from Pakistan through a liberation war in 1971. Considering the recruitment, training, and mobility of the bureaucrats, one characteristic of the public services in Bangladesh has been that they are divided into cadre and non-cadre services. The cadre services have distinct hierarchy and specified functions—specialized and generalized [33]. The members of these services belong to the Bangladesh Civil Service (BCS) who are recruited by the Public Service Commission (PSC) through highly competitive examinations. They are hired as Assistant Secretary or equivalent and can move to the Senior Secretary position through promotions. They can move from one department to another. On the other hand, members of the non-cadre services are recruited to particular departments and do not have a definite structure of mobility horizontally and vertically [34]. They need to serve within the department to which they are recruited. These bureaucrats have limited training opportunity throughout their service life. The frontline bureaucracy of Bangladesh has officials from both cadre and non-cadre services, but the size of the former category is smaller than the later.
Data for this study were collected from sub-district level frontline bureaucrats in Bangladesh using a survey questionnaire. Bangladesh had 488 sub-districts at the time of data collection. Twenty-nine sub-districts were chosen using a multistage sampling technique. From each of the selected sub-districts, 16 pre-decided office heads out of around 25 were given the questionnaire to fill out. The 16 office heads were chosen because they were perceived by practitioners as the frontline bureaucracies that had most interactions with citizens. Seven of these 16 offices are headed by cadre officials, and the rest nine offices are headed by non-cadre officials.
For data collection, the researcher traveled to the respondents. It was not possible to return with all filled-out questionnaires all the time. Therefore, questionnaires were left with the offices of those respondents where they were not available in their offices. It was not possible to contact each of these office heads before going to their offices. Instead, the chief executive officer (UNO) of the sub-district was contacted before going to that particular sub-district. The UNO office in a sub-district carries some importance because it plays a coordinating role among all the offices of the sub-district. After going to a sub-district, help from officials from the UNO office was obtained sometimes in distributing and collecting the questionnaires. Thus, the UNO office was used as the first contact point.
After going to a sub-district, this researcher went to each of the 16 selected offices in the sub-district. Where the office head was present, this researcher requested him or her to fill out the survey questionnaire. Where the office head was not present, his/her contact cell phone number was collected from the other officials of the office. Then the office head was contacted over the phone and requested to fill out the survey questionnaire when he/she was available in the office and was requested either to send the filled out questionnaire to the UNO office or the postal address of this researcher. In most cases, an envelope (with postage stamp) was left with the postal address of the researcher written on it.
Around 40% of the survey questionnaires, on average, were collected directly by the researcher. Some filled out questionnaires came directly from the respondents through the postal service. The remaining questionnaires were submitted to the UNO office, or the officials of the UNO office collected them from the other offices and then sent them together to the researcher through postal service. Altogether, 329 questionnaires were collected for the study out of the sample of 456. This constituted a response rate of 72.15%. However, three questionnaires were rejected because two of them had more than 50% items unanswered, and one was a duplicate. The duplication happened because one officer was in charge of two offices. That official filled out two questionnaires. Thus, one of these two questionnaires was rejected. Finally, data from 326 questionnaires were entered into the SPSS program. Demographic information of the respondents is presented in Table 2.
Demographic information of respondent (% in parenthesis).
The questionnaire had items taken from validated instruments to measure each of the cultural dimensions. Each item had a four-point scale which varied from “always” to “never” or “agree” to “disagree.” A five-item scale was constructed based on Jamil [6] to measure power distance. The items were: (1) I seek my subordinates’ opinions before making a decision; (2) My subordinates suggest me ideas about my office work; (3) Confident subordinates in my office disagree with my decisions; (4) I tell my subordinates what decisions are to be taken; and (5) When I am confident, I disagree with my higher authority. To measure uncertainty avoidance, a four-item scale was developed based on Jamil [6] which were: (1) I emphasize results more than following routines, procedures to the point; (2) I feel nervous about satisfying my higher authority with my work; (3) I look for the best alternative even if it goes beyond routines, and procedures; (4) I expect my higher authority to tell me if I am doing a good job. Participation was measured using a four-item scale developed following theoretical arguments. The items were: (1) My office should serve citizens according to their preferences; (2) Officers can learn nothing from service seekers; (3) My office should seek feedback from service recipients about their satisfaction; and (4) Service seekers should not advise us on what to do. Based on Harrison and Baird [3], a four-item scale was used to measure team orientation. The items were: (1) Working in teams can produce better results; (2) We should help each other in our office work; (3) Sometimes subordinates can give better opinions than superiors; (4) Subordinates should not disagree with the superior’s opinion.
Results of two independent samples t-tests and descriptive statistics of group differences in the means of the culture dimensions practiced by the cadre and non-cadre officials are presented in Table 3. Power distance in non-cadre officials is higher than in cadre officials. The difference is significant at 0.10 level of significance. Concerning uncertainty avoidance, the non-cadre officials again have a significantly higher tendency to avoid uncertainty compared to the cadre officials. The cadre officials’ mean score in the participation culture dimension is significantly higher than the mean score of the non-cadre officials. This finding is indicative of the cadre officials’ higher tendency to accommodate stakeholders in decision-making processes. With regard to team orientation, the mean score of cadre officials is also significantly higher than the non-cadre officials. Therefore, cadre officials possess a higher mentality of teamwork compared to non-cadre officials.
Results of t-test and descriptive statistics for culture dimensions by cadre.
The four culture dimensions influence the daily works of the frontline bureaucrats. Generally, power distance within an office context is an extension of the power distance that prevails in society. High power distance among the employees of an organization contributes to the fortification of its formal and rigid hierarchical structure. The cadre officials of the frontline bureaucracies inculcate this culture slightly less than the non-cadre officials and both scores are slightly lower than the average of the scale. Jamil [6] reported the existence of higher power distance in the cadre officials in general (central and frontline bureaucrats). Power distance in this study shows scores lower than the average (2.5 points on the scale of 4). Therefore, this culture has not changed much.
The culture of uncertainty avoidance tendency negatively affects the achievement of the targeted results of an organization. It bars officials from taking initiatives of innovation. Strict enforcement of bureaucratic procedures, in some contexts, may not fetch the desired results. Therefore, officials need to apply their discretion and take some risks, which might bring them some uncertainty. Generally, everyone wants to remain in his comfort zone. In public service delivery, when facing the complexity of local contexts, frontline bureaucrats need to come out of their comfort zones sometimes. This study found high uncertainty tendency in the frontline bureaucrats. The non-cadre officials have a greater tendency to avoid uncertainty than the cadre officials. High level of uncertainty avoidance tendency among the bureaucrats in Bangladesh was reported by Jamil [6], and the current scenario does not show any change.
Participation in this research was used to mean bureaucrats’ citizen-orientation, that is, their attitude toward feedback from citizens. The frontline bureaucrats directly deliver services to the citizens. Their understanding of the expectations of the citizens can equip them with appropriate services. The findings of this study show that the frontline bureaucrats have a very high tendency to get feedback from the citizens. Again the cadre officials are ahead of the non-cadre ones. This finding is also similar to that of Jamil [6].
The frontline bureaucrats show a positive attitude toward teamwork. The score of cadre officials is higher than the non-cadre officials. These frontline bureaucrats work in their offices with limited resources. They face huge workloads as well. These workloads happen because of two reasons. One reason is that the demand for services is very high. Bangladesh is a populous country. So these bureaucrats face more service seekers than the ideal size. The second reason is that many of the sanctioned positions in the frontline bureaucracies remain vacant. Therefore, the bureaucrats from within an organization need to cooperate among themselves through teamwork.
Organizational culture is difficult to change without a deliberate effort. In the public sector organizations, this change is even harder to bring. The bureaucrats are rule followers and change-resistant. They remain to be in their comfort zones. Bringing desired changes in the practice of culture will require conscious and deliberate efforts. These efforts may include education, training, and social campaign. The difference in the scores in the dimensions of culture practiced by the cadre and non-cadre bureaucrats can be attributed to the different outlook they develop through their participation in social events. Although both groups of bureaucrats come from the same social context, they become exposed to different social events. One obvious social event is training. The cadre bureaucrats take part in different long- and short-term training programs even at the very beginning of their services. The non-cadre bureaucrats hardly get any training. The second social factor is that the cadre bureaucrats, because of their mobility, attend various seminars and workshops on governance issues, which help them change their mindset. This scope is limited to the non-cadre bureaucrats.
This research had limitations. The items used to measure the culture dimensions in this research match the research context. The measurement tools might be different in other contexts. Future researchers can investigate why the cadre and non-cadre officials differ significantly in their organizational culture.
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This chapter aims to bring the reader a first-meeting introduction for quickly knowing about MREs, instead of a very deep understanding of MREs.",book:{id:"7685",slug:"smart-and-functional-soft-materials",title:"Smart and Functional Soft Materials",fullTitle:"Smart and Functional Soft Materials"},signatures:"Taixiang Liu and Yangguang Xu",authors:[{id:"283475",title:"Associate Prof.",name:"Yangguang",middleName:null,surname:"Xu",slug:"yangguang-xu",fullName:"Yangguang Xu"}]},{id:"38416",doi:"10.5772/50504",title:"Carbon Fibre Sensor: Theory and Application",slug:"carbon-fibre-sensor-theory-and-application",totalDownloads:3945,totalCrossrefCites:9,totalDimensionsCites:13,abstract:null,book:{id:"3052",slug:"composites-and-their-applications",title:"Composites and Their Applications",fullTitle:"Composites and Their Applications"},signatures:"Alexander Horoschenkoff and Christian Christner",authors:[{id:"142113",title:"Dr",name:"Alexander",middleName:null,surname:"Horoschenkoff",slug:"alexander-horoschenkoff",fullName:"Alexander Horoschenkoff"},{id:"142207",title:"Mr.",name:"Christian",middleName:null,surname:"Christner",slug:"christian-christner",fullName:"Christian Christner"}]},{id:"59283",doi:"10.5772/intechopen.73824",title:"Zeolite Mixed Matrix Membranes (Zeolite-MMMs) for Sustainable Engineering",slug:"zeolite-mixed-matrix-membranes-zeolite-mmms-for-sustainable-engineering",totalDownloads:1400,totalCrossrefCites:5,totalDimensionsCites:12,abstract:"Mixed matrix membranes (MMMs) could provide a solution to the permeability and selectivity trade-off in polymeric membranes and bridge the gap with inorganic membranes. 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This chapter aims to bring the reader a first-meeting introduction for quickly knowing about MREs, instead of a very deep understanding of MREs.",book:{id:"7685",slug:"smart-and-functional-soft-materials",title:"Smart and Functional Soft Materials",fullTitle:"Smart and Functional Soft Materials"},signatures:"Taixiang Liu and Yangguang Xu",authors:[{id:"283475",title:"Associate Prof.",name:"Yangguang",middleName:null,surname:"Xu",slug:"yangguang-xu",fullName:"Yangguang Xu"}]},{id:"67279",title:"Development, Characterization and Properties of Silk Fibre and Grafted Silk Fibre Reinforced Polymer Composite Films",slug:"development-characterization-and-properties-of-silk-fibre-and-grafted-silk-fibre-reinforced-polymer-",totalDownloads:1083,totalCrossrefCites:1,totalDimensionsCites:1,abstract:"The use of natural fibres over synthetic fibres is gaining widespread importance due to its availability; renewability, low density and satisfactory mechanical properties making them an ecological alternative to synthetic fibres. The innumerable properties of silk fibre have made it superior to be used by researchers both in the plastic and biomedical sector. Silk fibre reinforced PVA (polyvinylalcohol) and PVA/PVP (polyvinyl pyrrolidone) films were prepared via solution casting technique. The effect of silk fibre concentration, on the structural, thermal, mechanical, bio-degradable and the morphological properties of the composite films was assessed. The results indicated that the addition of silk fibres improved the thermal, morphological, mechanical and biodegradable properties of the films. The extensive use of silk fibroin in the biomedical field, due to its robust properties has made it a promising material, suitable in tissue engineering applications. Keeping this in view, the current study also focuses on re-tailoring the properties of silk fibres by grafting a natural polysaccharide like chitosan and thereby fabricate composite films of PVA reinforced with this grafted fibre. The films were tested for their potential applications in tissue engineering, by subjecting them to in vitro biocompatibility tests. The films were also tested for their antibacterial properties. The results thus obtained indicated that the films were non-toxic in all concentrations and were found to be suitable for biomaterial applications.",book:{id:"8162",slug:"generation-development-and-modifications-of-natural-fibers",title:"Generation, Development and Modifications of Natural Fibers",fullTitle:"Generation, Development and Modifications of Natural Fibers"},signatures:"Sareen Sheik and Gundibasappa Karikannar Nagaraja",authors:[{id:"285152",title:"Prof.",name:"G.K.",middleName:null,surname:"Nagaraja",slug:"g.k.-nagaraja",fullName:"G.K. 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This definition includes all natural cellulosic fibers (cotton, jute, sisal, coir, flax, hemp, abaca, ramie, etc.) and protein-based fibers such as wool and silk. There are also man-made cellulose fibers (e.g., viscose rayon and cellulose acetate) that are produced with chemical procedures from pulped wood or other sources (cotton, bamboo). Natural fibers being cost effective and abundantly available yields high potential in various industrial and commercial applications such as in the interior applications of the passenger cars, panels for partition and false ceiling, partition boards, roof tiles, coir fibers in packaging, furniture applications, as insulating materials in low energy houses, geo-textiles for soil protection and erosion control, enhancing barrier properties, composites etc. Due to research and developmental work in modification and treatment methods of natural fibers, utilization of natural fibers has observed a significant growth in various applications. The chapter addresses the potential applications of natural fibers in various commercial sectors for the development of environment-friendly products with an aim to replace synthetic fibers or inorganic fillers with cost-effective and efficient products.",book:{id:"8162",slug:"generation-development-and-modifications-of-natural-fibers",title:"Generation, Development and Modifications of Natural Fibers",fullTitle:"Generation, Development and Modifications of Natural Fibers"},signatures:"Jatinder Singh Dhaliwal",authors:[{id:"272683",title:"Mr.",name:"Jatinder Singh",middleName:null,surname:"Dhaliwal",slug:"jatinder-singh-dhaliwal",fullName:"Jatinder Singh Dhaliwal"}]}],onlineFirstChaptersFilter:{topicId:"934",limit:6,offset:0},onlineFirstChaptersCollection:[{id:"81461",title:"Fiber Inclusions-Based Epoxy Composites and Their Applications",slug:"fiber-inclusions-based-epoxy-composites-and-their-applications",totalDownloads:4,totalDimensionsCites:0,doi:"10.5772/intechopen.104118",abstract:"Because of their low cost, lightweight, easy production methods, and design flexibility, polymer-based composites are widely employed in a wide range of applications. Because of its high specific strength, superior mechanical characteristics, super adhesiveness, heat and solvent resistance, and so on, epoxy polymer or polyepoxide represent a significant majority of matrix composites. As a result, fiber fillers-reinforced epoxy resin composites have been investigated for a variety of applications, including high-tech in the ballistic, aircraft, automobile, construction, and sports sectors. In this chapter, the manufacturing procedures of fiber-reinforced epoxy composites have been described. Different categories of fiber are used as fillers in an epoxy matrix and their morphology is discussed as a function of the obtained properties.",book:{id:"11123",title:"Epoxy-Based Composites",coverURL:"https://cdn.intechopen.com/books/images_new/11123.jpg"},signatures:"Nassima Radouane and Abdelkrim Maaroufi"},{id:"81458",title:"Epoxy Composites for Radiation Shielding",slug:"epoxy-composites-for-radiation-shielding",totalDownloads:17,totalDimensionsCites:0,doi:"10.5772/intechopen.104117",abstract:"Due to the increase in use of radiation energy in many industrial applications, radiation shielding has become a crucial topic in order to diminish its hazardous effects. Radiation shields can be of various weights depending on the materials from which they are produced and the area in which they are used. In this sense, polymer composites have taken attention by researchers because it is aimed to obtain shields with good processability, sufficient flexibility, low weight, and subsequent performance properties. Epoxy resin is one of the mostly used synthetic polymers as a matrix element in composite material production due to its improving characteristics by means of electrical insulation, chemical resistance, service life, bonding characteristic, and mechanical properties. Besides, epoxies have intermediate radiation shielding characteristics as well. By loading epoxy matrix with fibers and/or fillers having different radiation absorption rates or mechanical resistance properties, multifunctional shields can be produced to serve in numerous applications. This chapter focuses on radiation shielding efficiency of fiber-reinforced epoxy composites and the role of fillers and fiber-based materials on manufacturing of functional radiation shields.",book:{id:"11123",title:"Epoxy-Based Composites",coverURL:"https://cdn.intechopen.com/books/images_new/11123.jpg"},signatures:"Hayriye Hale Aygün"},{id:"80631",title:"A Review on Mechanical Properties of Epoxy-Glass Composites Reinforced with Nanoclay",slug:"a-review-on-mechanical-properties-of-epoxy-glass-composites-reinforced-with-nanoclay",totalDownloads:76,totalDimensionsCites:0,doi:"10.5772/intechopen.102159",abstract:"Polymer nanocomposites are currently one of the most rapidly growing families of materials, and they are finding use in a wide range of industrial applications, including aerospace and defense. The broad usage of composites is because of their consolidated mechanical properties. Glass fiber reinforced epoxy composites are available for the last few decades. The idea of adding nano clay into it has emerged in the late first decade of this century. This study is aimed at reporting the effects of the addition of nano clay into GFRP on its mechanical properties. The new composite formed is epoxy-glass composites reinforced with nano clay (EGCN). Nano clay has a crystal structure that facilitates the formation of intercalated and exfoliated mixture with liquid epoxy during mixing which results in good dispersion of Nano clay thereby resulting in improved mechanical properties compared to GFRP. The work done by several researchers in this area and the results obtained are reported in this article. The improved mechanisms of failures were discussed with the addition of nano clays.",book:{id:"11123",title:"Epoxy-Based Composites",coverURL:"https://cdn.intechopen.com/books/images_new/11123.jpg"},signatures:"Shanti Kiran Zhade, Syam Kumar Chokka, V. Suresh Babu and K.V. Sai Srinadh"},{id:"80273",title:"Epoxy as Filler or Matrix for Polymer Composites",slug:"epoxy-as-filler-or-matrix-for-polymer-composites",totalDownloads:69,totalDimensionsCites:0,doi:"10.5772/intechopen.102448",abstract:"Epoxy is a widely used polymer because of its ease of processing, high adhesiveness, and high chemical resistance. Epoxy-based composites are commonly used in aerospace, automotive, and marine applications. The epoxy type, function, curing agent, and curing process are discussed in this chapter. Epoxy is used as either a filler or polymer matrix in composite applications. As a filler, the epoxy modification on the fiber is discussed. As a polymer matrix, the epoxy is reinforced by natural and synthetic fibers. The manufacturing process and the fabricated epoxy-based composites’ performance (e.g., mechanical and thermal properties) are investigated. The advantages and disadvantages of epoxy’s function are discussed and summarized. 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This chapter aims to introduce the synthesis, properties and development of ERAs and to illustrate how defects in their curing properties, thermal properties, brittleness and flammability affect their global development. Furthermore, this study introduces the modification of ERAs according to these defects and their development in main application fields. Lastly, the limitations and prospects of ERAs in future applications are also discussed.",book:{id:"11123",title:"Epoxy-Based Composites",coverURL:"https://cdn.intechopen.com/books/images_new/11123.jpg"},signatures:"Jun Zhang, Hai Luo, Xiaojian Zhou and Bowen Liu"}],onlineFirstChaptersTotal:5},preDownload:{success:null,errors:{}},subscriptionForm:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[],offset:8,limit:8,total:0},allSeries:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:9,numberOfPublishedChapters:87,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:98,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:27,numberOfPublishedChapters:287,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:9,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:11,numberOfPublishedChapters:139,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:8,numberOfPublishedChapters:129,numberOfOpenTopics:0,numberOfUpcomingTopics:2,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!1},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:107,numberOfOpenTopics:3,numberOfUpcomingTopics:1,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:10,numberOfPublishedChapters:103,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:12,numberOfOpenTopics:2,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:0,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!1},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:0,numberOfPublishedChapters:10,numberOfOpenTopics:4,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],testimonialsList:[{id:"13",text:"The collaboration with and support of the technical staff of IntechOpen is fantastic. The whole process of submitting an article and editing of the submitted article goes extremely smooth and fast, the number of reads and downloads of chapters is high, and the contributions are also frequently cited.",author:{id:"55578",name:"Antonio",surname:"Jurado-Navas",institutionString:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRisIQAS/Profile_Picture_1626166543950",slug:"antonio-jurado-navas",institution:{id:"720",name:"University of Malaga",country:{id:null,name:"Spain"}}}},{id:"6",text:"It is great to work with the IntechOpen to produce a worthwhile collection of research that also becomes a great educational resource and guide for future research endeavors.",author:{id:"259298",name:"Edward",surname:"Narayan",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259298/images/system/259298.jpeg",slug:"edward-narayan",institution:{id:"3",name:"University of Queensland",country:{id:null,name:"Australia"}}}}]},series:{item:{id:"7",title:"Biomedical Engineering",doi:"10.5772/intechopen.71985",issn:"2631-5343",scope:"Biomedical Engineering is one of the fastest-growing interdisciplinary branches of science and industry. The combination of electronics and computer science with biology and medicine has improved patient diagnosis, reduced rehabilitation time, and helped to facilitate a better quality of life. Nowadays, all medical imaging devices, medical instruments, or new laboratory techniques result from the cooperation of specialists in various fields. The series of Biomedical Engineering books covers such areas of knowledge as chemistry, physics, electronics, medicine, and biology. 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Dr. Koprowski has authored more than a hundred research papers with dozens in impact factor (IF) journals and has authored or co-authored six books. Additionally, he is the author of several national and international patents in the field of biomedical devices and imaging. 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From\r\n1964 to 1974, he worked as Assistant in Biochemistry at the School of MedicineUniversidad Nacional de La Plata, Argentina. From 1974 to 1976, he was a Fellowof the National Institutes of Health (NIH) at the University of Connecticut, Health Center, USA. From 1985 to 2004, he served as a Full Professor oBiochemistry at the Universidad Nacional de La Plata, Argentina. He is Member ofthe National Research Council (CONICET), Argentina, and Argentine Society foBiochemistry and Molecular Biology (SAIB). His laboratory has been interested for manyears in the lipid peroxidation of biological membranes from various tissues and different species. Professor Catalá has directed twelve doctoral theses, publishedover 100 papers in peer reviewed journals, several chapters in books andtwelve edited books. Angel Catalá received awards at the 40th InternationaConference Biochemistry of Lipids 1999: Dijon (France). W inner of the Bimbo PanAmerican Nutrition, Food Science and Technology Award 2006 and 2012, South AmericaHuman Nutrition, Professional Category. 2006 award in pharmacology, Bernardo\r\nHoussay, in recognition of his meritorious works of research. Angel Catalá belongto the Editorial Board of Journal of lipids, International Review of Biophysical ChemistryFrontiers in Membrane Physiology and Biophysics, World Journal oExperimental Medicine and Biochemistry Research International, W orld Journal oBiological Chemistry, Oxidative Medicine and Cellular Longevity, Diabetes and thePancreas, International Journal of Chronic Diseases & Therapy, International Journal oNutrition, Co-Editor of The Open Biology Journal.",institutionString:null,institution:{name:"National University of La Plata",institutionURL:null,country:{name:"Argentina"}}},editorTwo:null,editorThree:null},{id:"12",title:"Human Physiology",coverUrl:"https://cdn.intechopen.com/series_topics/covers/12.jpg",isOpenForSubmission:!0,editor:{id:"195829",title:"Prof.",name:"Kunihiro",middleName:null,surname:"Sakuma",slug:"kunihiro-sakuma",fullName:"Kunihiro Sakuma",profilePictureURL:"https://mts.intechopen.com/storage/users/195829/images/system/195829.jpg",biography:"Professor Kunihiro Sakuma, Ph.D., currently works in the Institute for Liberal Arts at the Tokyo Institute of Technology. He is a physiologist working in the field of skeletal muscle. He was awarded his sports science diploma in 1995 by the University of Tsukuba and began his scientific work at the Department of Physiology, Aichi Human Service Center, focusing on the molecular mechanism of congenital muscular dystrophy and normal muscle regeneration. His interest later turned to the molecular mechanism and attenuating strategy of sarcopenia (age-related muscle atrophy). His opinion is to attenuate sarcopenia by improving autophagic defects using nutrient- and pharmaceutical-based treatments.",institutionString:null,institution:{name:"Tokyo Institute of Technology",institutionURL:null,country:{name:"Japan"}}},editorTwo:null,editorThree:{id:"331519",title:"Dr.",name:"Kotomi",middleName:null,surname:"Sakai",slug:"kotomi-sakai",fullName:"Kotomi Sakai",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000031QtFXQA0/Profile_Picture_1637053227318",biography:"Senior researcher Kotomi Sakai, Ph.D., MPH, works at the Research Organization of Science and Technology in Ritsumeikan University. She is a researcher in the geriatric rehabilitation and public health field. She received Ph.D. from Nihon University and MPH from St.Luke’s International University. Her main research interest is sarcopenia in older adults, especially its association with nutritional status. Additionally, to understand how to maintain and improve physical function in older adults, to conduct studies about the mechanism of sarcopenia and determine when possible interventions are needed.",institutionString:null,institution:{name:"Ritsumeikan University",institutionURL:null,country:{name:"Japan"}}}},{id:"13",title:"Plant Physiology",coverUrl:"https://cdn.intechopen.com/series_topics/covers/13.jpg",isOpenForSubmission:!0,editor:{id:"332229",title:"Prof.",name:"Jen-Tsung",middleName:null,surname:"Chen",slug:"jen-tsung-chen",fullName:"Jen-Tsung Chen",profilePictureURL:"https://mts.intechopen.com/storage/users/332229/images/system/332229.png",biography:"Dr. Jen-Tsung Chen is currently a professor at the National University of Kaohsiung, Taiwan. He teaches cell biology, genomics, proteomics, medicinal plant biotechnology, and plant tissue culture. Dr. Chen\\'s research interests include bioactive compounds, chromatography techniques, in vitro culture, medicinal plants, phytochemicals, and plant biotechnology. He has published more than ninety scientific papers and serves as an editorial board member for Plant Methods, Biomolecules, and International Journal of Molecular Sciences.",institutionString:"National University of Kaohsiung",institution:{name:"National University of Kaohsiung",institutionURL:null,country:{name:"Taiwan"}}},editorTwo:null,editorThree:null}]},overviewPageOFChapters:{paginationCount:43,paginationItems:[{id:"81796",title:"Apoptosis-Related Diseases and Peroxisomes",doi:"10.5772/intechopen.105052",signatures:"Meimei Wang, Yakun Liu, Ni Chen, Juan Wang and Ye Zhao",slug:"apoptosis-related-diseases-and-peroxisomes",totalDownloads:3,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"The Metabolic Role of Peroxisome in Health and Disease",coverURL:"https://cdn.intechopen.com/books/images_new/10837.jpg",subseries:{id:"11",title:"Cell Physiology"}}},{id:"81723",title:"Peroxisomal Modulation as Therapeutic Alternative for Tackling Multiple Cancers",doi:"10.5772/intechopen.104873",signatures:"Shazia Usmani, Shadma Wahab, Abdul Hafeez, Shabana Khatoon and Syed Misbahul Hasan",slug:"peroxisomal-modulation-as-therapeutic-alternative-for-tackling-multiple-cancers",totalDownloads:3,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"The Metabolic Role of Peroxisome in Health and Disease",coverURL:"https://cdn.intechopen.com/books/images_new/10837.jpg",subseries:{id:"11",title:"Cell Physiology"}}},{id:"81638",title:"Aging and Neuropsychiatric Disease: A General Overview of Prevalence and Trends",doi:"10.5772/intechopen.103102",signatures:"Jelena Milić",slug:"aging-and-neuropsychiatric-disease-a-general-overview-of-prevalence-and-trends",totalDownloads:14,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Senescence",coverURL:"https://cdn.intechopen.com/books/images_new/10935.jpg",subseries:{id:"11",title:"Cell Physiology"}}},{id:"81566",title:"New and Emerging Technologies for Integrative Ambulatory Autonomic Assessment and Intervention as a Catalyst in the Synergy of Remote Geocoded Biosensing, Algorithmic Networked Cloud Computing, Deep Learning, and Regenerative/Biomic Medicine: Further Real",doi:"10.5772/intechopen.104092",signatures:"Robert L. Drury",slug:"new-and-emerging-technologies-for-integrative-ambulatory-autonomic-assessment-and-intervention-as-a-",totalDownloads:9,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Autonomic Nervous System - Special Interest Topics",coverURL:"https://cdn.intechopen.com/books/images_new/10835.jpg",subseries:{id:"12",title:"Human Physiology"}}}]},overviewPagePublishedBooks:{paginationCount:11,paginationItems:[{type:"book",id:"7264",title:"Calcium and Signal Transduction",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7264.jpg",slug:"calcium-and-signal-transduction",publishedDate:"October 24th 2018",editedByType:"Edited by",bookSignature:"John N. Buchholz and Erik J. Behringer",hash:"e373a3d1123dbd45fddf75d90e3e7c38",volumeInSeries:1,fullTitle:"Calcium and Signal Transduction",editors:[{id:"89438",title:"Dr.",name:"John N.",middleName:null,surname:"Buchholz",slug:"john-n.-buchholz",fullName:"John N. Buchholz",profilePictureURL:"https://mts.intechopen.com/storage/users/89438/images/6463_n.jpg",biography:"Full Professor and Vice Chair, Division of Pharmacology, Loma Linda University, School of Medicine. He received his B.S. Degree in Biology at La Sierra University, Riverside California (1980) and a PhD in Pharmacology from Loma Linda University School of Medicine (1988). Post-Doctoral Fellow at University of California, Irvine, College of Medicine 1989-1992 with a focus on autonomic nerve function in blood vessels and the impact of aging on the function of these nerves and overall blood vessel function. Twenty years of research funding and served on NIH R01 review panels, Editor-In-Chief of Edorium Journal of Aging Research. Serves as a peer reviewer for biomedical journals. Military Reserve Officer serving with the 100 Support Command, 100 Troop Command, 40 Infantry Division, CA National Guard.",institutionString:null,institution:{name:"Loma Linda University",institutionURL:null,country:{name:"United States of America"}}}]},{type:"book",id:"6925",title:"Endoplasmic Reticulum",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/6925.jpg",slug:"endoplasmic-reticulum",publishedDate:"April 17th 2019",editedByType:"Edited by",bookSignature:"Angel Català",hash:"a9e90d2dbdbc46128dfe7dac9f87c6b4",volumeInSeries:2,fullTitle:"Endoplasmic Reticulum",editors:[{id:"196544",title:"Prof.",name:"Angel",middleName:null,surname:"Catala",slug:"angel-catala",fullName:"Angel Catala",profilePictureURL:"https://mts.intechopen.com/storage/users/196544/images/system/196544.jpg",biography:"Angel Catalá studied chemistry at Universidad Nacional de La Plata, Argentina, where he received a Ph.D. in Chemistry (Biological Branch) in 1965. From 1964 to 1974, he worked as an Assistant in Biochemistry at the School of Medicine at the same university. From 1974 to 1976, he was a fellow of the National Institutes of Health (NIH) at the University of Connecticut, Health Center, USA. From 1985 to 2004, he served as a Full Professor of Biochemistry at the Universidad Nacional de La Plata. He is a member of the National Research Council (CONICET), Argentina, and the Argentine Society for Biochemistry and Molecular Biology (SAIB). His laboratory has been interested for many years in the lipid peroxidation of biological membranes from various tissues and different species. Dr. Catalá has directed twelve doctoral theses, published more than 100 papers in peer-reviewed journals, several chapters in books, and edited twelve books. He received awards at the 40th International Conference Biochemistry of Lipids 1999 in Dijon, France. He is the winner of the Bimbo Pan-American Nutrition, Food Science and Technology Award 2006 and 2012, South America, Human Nutrition, Professional Category. In 2006, he won the Bernardo Houssay award in pharmacology, in recognition of his meritorious works of research. Dr. Catalá belongs to the editorial board of several journals including Journal of Lipids; International Review of Biophysical Chemistry; Frontiers in Membrane Physiology and Biophysics; World Journal of Experimental Medicine and Biochemistry Research International; World Journal of Biological Chemistry, Diabetes, and the Pancreas; International Journal of Chronic Diseases & Therapy; and International Journal of Nutrition. He is the co-editor of The Open Biology Journal and associate editor for Oxidative Medicine and Cellular Longevity.",institutionString:"Universidad Nacional de La Plata",institution:{name:"National University of La Plata",institutionURL:null,country:{name:"Argentina"}}}]},{type:"book",id:"6924",title:"Adenosine Triphosphate in Health and Disease",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/6924.jpg",slug:"adenosine-triphosphate-in-health-and-disease",publishedDate:"April 24th 2019",editedByType:"Edited by",bookSignature:"Gyula Mozsik",hash:"04106c232a3c68fec07ba7cf00d2522d",volumeInSeries:3,fullTitle:"Adenosine Triphosphate in Health and Disease",editors:[{id:"58390",title:"Dr.",name:"Gyula",middleName:null,surname:"Mozsik",slug:"gyula-mozsik",fullName:"Gyula Mozsik",profilePictureURL:"https://mts.intechopen.com/storage/users/58390/images/system/58390.png",biography:"Gyula Mózsik MD, Ph.D., ScD (med), is an emeritus professor of Medicine at the First Department of Medicine, Univesity of Pécs, Hungary. He was head of this department from 1993 to 2003. His specializations are medicine, gastroenterology, clinical pharmacology, clinical nutrition, and dietetics. His research fields are biochemical pharmacological examinations in the human gastrointestinal (GI) mucosa, mechanisms of retinoids, drugs, capsaicin-sensitive afferent nerves, and innovative pharmacological, pharmaceutical, and nutritional (dietary) research in humans. He has published about 360 peer-reviewed papers, 197 book chapters, 692 abstracts, 19 monographs, and has edited 37 books. He has given about 1120 regular and review lectures. He has organized thirty-eight national and international congresses and symposia. He is the founder of the International Conference on Ulcer Research (ICUR); International Union of Pharmacology, Gastrointestinal Section (IUPHAR-GI); Brain-Gut Society symposiums, and gastrointestinal cytoprotective symposiums. He received the Andre Robert Award from IUPHAR-GI in 2014. 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He has been reviewer for several publications of the Optical Society of America\\'s including Photonics Technology Letters and Applied Optics.\n\nPersonal Interests\nThese include motor cycling in a very relaxed manner and performing martial arts.",institutionString:null,institution:{name:"Charité",country:{name:"Germany"}}},{id:"341622",title:"Ph.D.",name:"Eduardo",middleName:null,surname:"Rojas Alvarez",slug:"eduardo-rojas-alvarez",fullName:"Eduardo Rojas Alvarez",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/341622/images/15892_n.jpg",biography:null,institutionString:null,institution:{name:"University of Cuenca",country:{name:"Ecuador"}}},{id:"215610",title:"Prof.",name:"Muhammad",middleName:null,surname:"Sarfraz",slug:"muhammad-sarfraz",fullName:"Muhammad Sarfraz",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/215610/images/system/215610.jpeg",biography:"Muhammad Sarfraz is a professor in the Department of Information Science, Kuwait University, Kuwait. His research interests include optimization, computer graphics, computer vision, image processing, machine learning, pattern recognition, soft computing, data science, and intelligent systems. Prof. Sarfraz has been a keynote/invited speaker at various platforms around the globe. He has advised/supervised more than 110 students for their MSc and Ph.D. theses. He has published more than 400 publications as books, journal articles, and conference papers. He has authored and/or edited around seventy books. Prof. Sarfraz is a member of various professional societies. He is a chair and member of international advisory committees and organizing committees of numerous international conferences. He is also an editor and editor in chief for various international journals.",institutionString:"Kuwait University",institution:{name:"Kuwait University",country:{name:"Kuwait"}}},{id:"32650",title:"Prof.",name:"Lukas",middleName:"Willem",surname:"Snyman",slug:"lukas-snyman",fullName:"Lukas Snyman",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/32650/images/4136_n.jpg",biography:"Lukas Willem Snyman received his basic education at primary and high schools in South Africa, Eastern Cape. He enrolled at today's Nelson Metropolitan University and graduated from this university with a BSc in Physics and Mathematics, B.Sc Honors in Physics, MSc in Semiconductor Physics, and a Ph.D. in Semiconductor Physics in 1987. After his studies, he chose an academic career and devoted his energy to the teaching of physics to first, second, and third-year students. After positions as a lecturer at the University of Port Elizabeth, he accepted a position as Associate Professor at the University of Pretoria, South Africa.\r\n\r\nIn 1992, he motivates the concept of 'television and computer-based education” as means to reach large student numbers with only the best of teaching expertise and publishes an article on the concept in the SA Journal of Higher Education of 1993 (and later in 2003). The University of Pretoria subsequently approved a series of test projects on the concept with outreach to Mamelodi and Eerste Rust in 1993. In 1994, the University established a 'Unit for Telematic Education ' as a support section for multiple faculties at the University of Pretoria. In subsequent years, the concept of 'telematic education” subsequently becomes well established in academic circles in South Africa, grew in popularity, and is adopted by many universities and colleges throughout South Africa as a medium of enhancing education and training, as a method to reaching out to far out communities, and as a means to enhance study from the home environment.\r\n\r\nProfessor Snyman in subsequent years pursued research in semiconductor physics, semiconductor devices, microelectronics, and optoelectronics.\r\n\r\nIn 2000 he joined the TUT as a full professor. Here served for a period as head of the Department of Electronic Engineering. Here he makes contributions to solar energy development, microwave and optoelectronic device development, silicon photonics, as well as contributions to new mobile telecommunication systems and network planning in SA.\r\n\r\nCurrently, he teaches electronics and telecommunications at the TUT to audiences ranging from first-year students to Ph.D. level.\r\n\r\nFor his research in the field of 'Silicon Photonics” since 1990, he has published (as author and co-author) about thirty internationally reviewed articles in scientific journals, contributed to more than forty international conferences, about 25 South African provisional patents (as inventor and co-inventor), 8 PCT international patent applications until now. Of these, two USA patents applications, two European Patents, two Korean patents, and ten SA patents have been granted. A further 4 USA patents, 5 European patents, 3 Korean patents, 3 Chinese patents, and 3 Japanese patents are currently under consideration.\r\n\r\nRecently he has also published an extensive scholarly chapter in an internet open access book on 'Integrating Microphotonic Systems and MOEMS into standard Silicon CMOS Integrated circuitry”.\r\n\r\nFurthermore, Professor Snyman recently steered a new initiative at the TUT by introducing a 'Laboratory for Innovative Electronic Systems ' at the Department of Electrical Engineering. The model of this laboratory or center is to primarily combine outputs as achieved by high-level research with lower-level system development and entrepreneurship in a technical university environment. Students are allocated to projects at different levels with PhDs and Master students allocated to the generation of new knowledge and new technologies, while students at the diploma and Baccalaureus level are allocated to electronic systems development with a direct and a near application for application in industry or the commercial and public sectors in South Africa.\r\n\r\nProfessor Snyman received the WIRSAM Award of 1983 and the WIRSAM Award in 1985 in South Africa for best research papers by a young scientist at two international conferences on electron microscopy in South Africa. He subsequently received the SA Microelectronics Award for the best dissertation emanating from studies executed at a South African university in the field of Physics and Microelectronics in South Africa in 1987. In October of 2011, Professor Snyman received the prestigious Institutional Award for 'Innovator of the Year” for 2010 at the Tshwane University of Technology, South Africa. This award was based on the number of patents recognized and granted by local and international institutions as well as for his contributions concerning innovation at the TUT.",institutionString:null,institution:{name:"University of South Africa",country:{name:"South Africa"}}},{id:"317279",title:"Mr.",name:"Ali",middleName:"Usama",surname:"Syed",slug:"ali-syed",fullName:"Ali Syed",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/317279/images/16024_n.png",biography:"A creative, talented, and innovative young professional who is dedicated, well organized, and capable research fellow with two years of experience in graduate-level research, published in engineering journals and book, with related expertise in Bio-robotics, equally passionate about the aesthetics of the mechanical and electronic system, obtained expertise in the use of MS Office, MATLAB, SolidWorks, LabVIEW, Proteus, Fusion 360, having a grasp on python, C++ and assembly language, possess proven ability in acquiring research grants, previous appointments with social and educational societies with experience in administration, current affiliations with IEEE and Web of Science, a confident presenter at conferences and teacher in classrooms, able to explain complex information to audiences of all levels.",institutionString:null,institution:{name:"Air University",country:{name:"Pakistan"}}},{id:"75526",title:"Ph.D.",name:"Zihni Onur",middleName:null,surname:"Uygun",slug:"zihni-onur-uygun",fullName:"Zihni Onur Uygun",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/75526/images/12_n.jpg",biography:"My undergraduate education and my Master of Science educations at Ege University and at Çanakkale Onsekiz Mart University have given me a firm foundation in Biochemistry, Analytical Chemistry, Biosensors, Bioelectronics, Physical Chemistry and Medicine. After obtaining my degree as a MSc in analytical chemistry, I started working as a research assistant in Ege University Medical Faculty in 2014. In parallel, I enrolled to the MSc program at the Department of Medical Biochemistry at Ege University to gain deeper knowledge on medical and biochemical sciences as well as clinical chemistry in 2014. In my PhD I deeply researched on biosensors and bioelectronics and finished in 2020. Now I have eleven SCI-Expanded Index published papers, 6 international book chapters, referee assignments for different SCIE journals, one international patent pending, several international awards, projects and bursaries. In parallel to my research assistant position at Ege University Medical Faculty, Department of Medical Biochemistry, in April 2016, I also founded a Start-Up Company (Denosens Biotechnology LTD) by the support of The Scientific and Technological Research Council of Turkey. Currently, I am also working as a CEO in Denosens Biotechnology. The main purposes of the company, which carries out R&D as a research center, are to develop new generation biosensors and sensors for both point-of-care diagnostics; such as glucose, lactate, cholesterol and cancer biomarker detections. My specific experimental and instrumental skills are Biochemistry, Biosensor, Analytical Chemistry, Electrochemistry, Mobile phone based point-of-care diagnostic device, POCTs and Patient interface designs, HPLC, Tandem Mass Spectrometry, Spectrophotometry, ELISA.",institutionString:null,institution:{name:"Ege University",country:{name:"Turkey"}}},{id:"246502",title:"Dr.",name:"Jaya T.",middleName:"T",surname:"Varkey",slug:"jaya-t.-varkey",fullName:"Jaya T. Varkey",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/246502/images/11160_n.jpg",biography:"Jaya T. Varkey, PhD, graduated with a degree in Chemistry from Cochin University of Science and Technology, Kerala, India. She obtained a PhD in Chemistry from the School of Chemical Sciences, Mahatma Gandhi University, Kerala, India, and completed a post-doctoral fellowship at the University of Minnesota, USA. She is a research guide at Mahatma Gandhi University and Associate Professor in Chemistry, St. Teresa’s College, Kochi, Kerala, India.\nDr. Varkey received a National Young Scientist award from the Indian Science Congress (1995), a UGC Research award (2016–2018), an Indian National Science Academy (INSA) Visiting Scientist award (2018–2019), and a Best Innovative Faculty award from the All India Association for Christian Higher Education (AIACHE) (2019). She Hashas received the Sr. Mary Cecil prize for best research paper three times. She was also awarded a start-up to develop a tea bag water filter. \nDr. Varkey has published two international books and twenty-seven international journal publications. She is an editorial board member for five international journals.",institutionString:"St. Teresa’s College",institution:null},{id:"250668",title:"Dr.",name:"Ali",middleName:null,surname:"Nabipour Chakoli",slug:"ali-nabipour-chakoli",fullName:"Ali Nabipour Chakoli",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/250668/images/system/250668.jpg",biography:"Academic Qualification:\r\n•\tPhD in Materials Physics and Chemistry, From: Sep. 2006, to: Sep. 2010, School of Materials Science and Engineering, Harbin Institute of Technology, Thesis: Structure and Shape Memory Effect of Functionalized MWCNTs/poly (L-lactide-co-ε-caprolactone) Nanocomposites. Supervisor: Prof. Wei Cai,\r\n•\tM.Sc in Applied Physics, From: 1996, to: 1998, Faculty of Physics & Nuclear Science, Amirkabir Uni. of Technology, Tehran, Iran, Thesis: Determination of Boron in Micro alloy Steels with solid state nuclear track detectors by neutron induced auto radiography, Supervisors: Dr. M. Hosseini Ashrafi and Dr. A. Hosseini.\r\n•\tB.Sc. in Applied Physics, From: 1991, to: 1996, Faculty of Physics & Nuclear Science, Amirkabir Uni. of Technology, Tehran, Iran, Thesis: Design of shielding for Am-Be neutron sources for In Vivo neutron activation analysis, Supervisor: Dr. M. Hosseini Ashrafi.\r\n\r\nResearch Experiences:\r\n1.\tNanomaterials, Carbon Nanotubes, Graphene: Synthesis, Functionalization and Characterization,\r\n2.\tMWCNTs/Polymer Composites: Fabrication and Characterization, \r\n3.\tShape Memory Polymers, Biodegradable Polymers, ORC, Collagen,\r\n4.\tMaterials Analysis and Characterizations: TEM, SEM, XPS, FT-IR, Raman, DSC, DMA, TGA, XRD, GPC, Fluoroscopy, \r\n5.\tInteraction of Radiation with Mater, Nuclear Safety and Security, NDT(RT),\r\n6.\tRadiation Detectors, Calibration (SSDL),\r\n7.\tCompleted IAEA e-learning Courses:\r\nNuclear Security (15 Modules),\r\nNuclear Safety:\r\nTSA 2: Regulatory Protection in Occupational Exposure,\r\nTips & Tricks: Radiation Protection in Radiography,\r\nSafety and Quality in Radiotherapy,\r\nCourse on Sealed Radioactive Sources,\r\nCourse on Fundamentals of Environmental Remediation,\r\nCourse on Planning for Environmental Remediation,\r\nKnowledge Management Orientation Course,\r\nFood Irradiation - Technology, Applications and Good Practices,\r\nEmployment:\r\nFrom 2010 to now: Academic staff, Nuclear Science and Technology Research Institute, Kargar Shomali, Tehran, Iran, P.O. Box: 14395-836.\r\nFrom 1997 to 2006: Expert of Materials Analysis and Characterization. Research Center of Agriculture and Medicine. Rajaeeshahr, Karaj, Iran, P. O. Box: 31585-498.",institutionString:"Atomic Energy Organization of Iran",institution:{name:"Atomic Energy Organization of Iran",country:{name:"Iran"}}},{id:"248279",title:"Dr.",name:"Monika",middleName:"Elzbieta",surname:"Machoy",slug:"monika-machoy",fullName:"Monika Machoy",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/248279/images/system/248279.jpeg",biography:"Monika Elżbieta Machoy, MD, graduated with distinction from the Faculty of Medicine and Dentistry at the Pomeranian Medical University in 2009, defended her PhD thesis with summa cum laude in 2016 and is currently employed as a researcher at the Department of Orthodontics of the Pomeranian Medical University. She expanded her professional knowledge during a one-year scholarship program at the Ernst Moritz Arndt University in Greifswald, Germany and during a three-year internship at the Technical University in Dresden, Germany. She has been a speaker at numerous orthodontic conferences, among others, American Association of Orthodontics, European Orthodontic Symposium and numerous conferences of the Polish Orthodontic Society. She conducts research focusing on the effect of orthodontic treatment on dental and periodontal tissues and the causes of pain in orthodontic patients.",institutionString:"Pomeranian Medical University",institution:{name:"Pomeranian Medical University",country:{name:"Poland"}}},{id:"252743",title:"Prof.",name:"Aswini",middleName:"Kumar",surname:"Kar",slug:"aswini-kar",fullName:"Aswini Kar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/252743/images/10381_n.jpg",biography:"uploaded in cv",institutionString:null,institution:{name:"KIIT University",country:{name:"India"}}},{id:"204256",title:"Dr.",name:"Anil",middleName:"Kumar",surname:"Kumar Sahu",slug:"anil-kumar-sahu",fullName:"Anil Kumar Sahu",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/204256/images/14201_n.jpg",biography:"I have nearly 11 years of research and teaching experience. I have done my master degree from University Institute of Pharmacy, Pt. Ravi Shankar Shukla University, Raipur, Chhattisgarh India. I have published 16 review and research articles in international and national journals and published 4 chapters in IntechOpen, the world’s leading publisher of Open access books. I have presented many papers at national and international conferences. I have received research award from Indian Drug Manufacturers Association in year 2015. My research interest extends from novel lymphatic drug delivery systems, oral delivery system for herbal bioactive to formulation optimization.",institutionString:null,institution:{name:"Chhattisgarh Swami Vivekanand Technical University",country:{name:"India"}}},{id:"253468",title:"Dr.",name:"Mariusz",middleName:null,surname:"Marzec",slug:"mariusz-marzec",fullName:"Mariusz Marzec",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/253468/images/system/253468.png",biography:"An assistant professor at Department of Biomedical Computer Systems, at Institute of Computer Science, Silesian University in Katowice. Scientific interests: computer analysis and processing of images, biomedical images, databases and programming languages. He is an author and co-author of scientific publications covering analysis and processing of biomedical images and development of database systems.",institutionString:"University of Silesia",institution:null},{id:"212432",title:"Prof.",name:"Hadi",middleName:null,surname:"Mohammadi",slug:"hadi-mohammadi",fullName:"Hadi Mohammadi",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/212432/images/system/212432.jpeg",biography:"Dr. Hadi Mohammadi is a biomedical engineer with hands-on experience in the design and development of many engineering structures and medical devices through various projects that he has been involved in over the past twenty years. Dr. Mohammadi received his BSc. and MSc. degrees in Mechanical Engineering from Sharif University of Technology, Tehran, Iran, and his PhD. degree in Biomedical Engineering (biomaterials) from the University of Western Ontario. He was a postdoctoral trainee for almost four years at University of Calgary and Harvard Medical School. He is an industry innovator having created the technology to produce lifelike synthetic platforms that can be used for the simulation of almost all cardiovascular reconstructive surgeries. He’s been heavily involved in the design and development of cardiovascular devices and technology for the past 10 years. He is currently an Assistant Professor with the University of British Colombia, Canada.",institutionString:"University of British Columbia",institution:{name:"University of British Columbia",country:{name:"Canada"}}},{id:"254463",title:"Prof.",name:"Haisheng",middleName:null,surname:"Yang",slug:"haisheng-yang",fullName:"Haisheng Yang",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/254463/images/system/254463.jpeg",biography:"Haisheng Yang, Ph.D., Professor and Director of the Department of Biomedical Engineering, College of Life Science and Bioengineering, Beijing University of Technology. He received his Ph.D. degree in Mechanics/Biomechanics from Harbin Institute of Technology (jointly with University of California, Berkeley). Afterwards, he worked as a Postdoctoral Research Associate in the Purdue Musculoskeletal Biology and Mechanics Lab at the Department of Basic Medical Sciences, Purdue University, USA. He also conducted research in the Research Centre of Shriners Hospitals for Children-Canada at McGill University, Canada. Dr. Yang has over 10 years research experience in orthopaedic biomechanics and mechanobiology of bone adaptation and regeneration. He earned an award from Beijing Overseas Talents Aggregation program in 2017 and serves as Beijing Distinguished Professor.",institutionString:"Beijing University of Technology",institution:null},{id:"255757",title:"Dr.",name:"Igor",middleName:"Victorovich",surname:"Lakhno",slug:"igor-lakhno",fullName:"Igor Lakhno",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/255757/images/system/255757.jpg",biography:"Lakhno Igor Victorovich was born in 1971 in Kharkiv (Ukraine). \nMD – 1994, Kharkiv National Medical Univesity.\nOb&Gyn; – 1997, master courses in Kharkiv Medical Academy of Postgraduate Education.\nPhD – 1999, Kharkiv National Medical Univesity.\nDSc – 2019, PL Shupik National Academy of Postgraduate Education \nLakhno Igor has been graduated from an international training courses on reproductive medicine and family planning held in Debrecen University (Hungary) in 1997. Since 1998 Lakhno Igor has worked as an associate professor of the department of obstetrics and gynecology of VN Karazin National University and an associate professor of the perinatology, obstetrics and gynecology department of Kharkiv Medical Academy of Postgraduate Education. Since June 2019 he’s a professor of the department of obstetrics and gynecology of VN Karazin National University and a professor of the perinatology, obstetrics and gynecology department of Kharkiv Medical Academy of Postgraduate Education . He’s an author of about 200 printed works and there are 17 of them in Scopus or Web of Science databases. Lakhno Igor is a rewiever of Journal of Obstetrics and Gynaecology (Taylor and Francis), Informatics in Medicine Unlocked (Elsevier), The Journal of Obstetrics and Gynecology Research (Wiley), Endocrine, Metabolic & Immune Disorders-Drug Targets (Bentham Open), The Open Biomedical Engineering Journal (Bentham Open), etc. He’s defended a dissertation for DSc degree \\'Pre-eclampsia: prediction, prevention and treatment”. Lakhno Igor has participated as a speaker in several international conferences and congresses (International Conference on Biological Oscillations April 10th-14th 2016, Lancaster, UK, The 9th conference of the European Study Group on Cardiovascular Oscillations). His main scientific interests: obstetrics, women’s health, fetal medicine, cardiovascular medicine.",institutionString:"V.N. Karazin Kharkiv National University",institution:{name:"Kharkiv Medical Academy of Postgraduate Education",country:{name:"Ukraine"}}},{id:"89721",title:"Dr.",name:"Mehmet",middleName:"Cuneyt",surname:"Ozmen",slug:"mehmet-ozmen",fullName:"Mehmet Ozmen",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/89721/images/7289_n.jpg",biography:null,institutionString:null,institution:{name:"Gazi University",country:{name:"Turkey"}}},{id:"243698",title:"M.D.",name:"Xiaogang",middleName:null,surname:"Wang",slug:"xiaogang-wang",fullName:"Xiaogang Wang",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/243698/images/system/243698.png",biography:"Dr. Xiaogang Wang, a faculty member of Shanxi Eye Hospital specializing in the treatment of cataract and retinal disease and a tutor for postgraduate students of Shanxi Medical University, worked in the COOL Lab as an international visiting scholar under the supervision of Dr. David Huang and Yali Jia from October 2012 through November 2013. Dr. Wang earned an MD from Shanxi Medical University and a Ph.D. from Shanghai Jiao Tong University. Dr. Wang was awarded two research project grants focused on multimodal optical coherence tomography imaging and deep learning in cataract and retinal disease, from the National Natural Science Foundation of China. He has published around 30 peer-reviewed journal papers and four book chapters and co-edited one book.",institutionString:"Shanxi Eye Hospital",institution:{name:"Shanxi Eye Hospital",country:{name:"China"}}},{id:"242893",title:"Ph.D. Student",name:"Joaquim",middleName:null,surname:"De Moura",slug:"joaquim-de-moura",fullName:"Joaquim De Moura",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/242893/images/7133_n.jpg",biography:"Joaquim de Moura received his degree in Computer Engineering in 2014 from the University of A Coruña (Spain). In 2016, he received his M.Sc degree in Computer Engineering from the same university. He is currently pursuing his Ph.D degree in Computer Science in a collaborative project between ophthalmology centers in Galicia and the University of A Coruña. His research interests include computer vision, machine learning algorithms and analysis and medical imaging processing of various kinds.",institutionString:null,institution:{name:"University of A Coruña",country:{name:"Spain"}}},{id:"267434",title:"Dr.",name:"Rohit",middleName:null,surname:"Raja",slug:"rohit-raja",fullName:"Rohit Raja",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRZkkQAG/Profile_Picture_2022-05-09T12:55:18.jpg",biography:null,institutionString:null,institution:null},{id:"294334",title:"B.Sc.",name:"Marc",middleName:null,surname:"Bruggeman",slug:"marc-bruggeman",fullName:"Marc Bruggeman",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/294334/images/8242_n.jpg",biography:"Chemical engineer graduate, with a passion for material science and specific interest in polymers - their near infinite applications intrigue me. \n\nI plan to continue my scientific career in the field of polymeric biomaterials as I am fascinated by intelligent, bioactive and biomimetic materials for use in both consumer and medical applications.",institutionString:null,institution:null},{id:"244950",title:"Dr.",name:"Salvatore",middleName:null,surname:"Di Lauro",slug:"salvatore-di-lauro",fullName:"Salvatore Di Lauro",position:null,profilePictureURL:"https://intech-files.s3.amazonaws.com/0030O00002bSF1HQAW/ProfilePicture%202021-12-20%2014%3A54%3A14.482",biography:"Name:\n\tSALVATORE DI LAURO\nAddress:\n\tHospital Clínico Universitario Valladolid\nAvda Ramón y Cajal 3\n47005, Valladolid\nSpain\nPhone number: \nFax\nE-mail:\n\t+34 983420000 ext 292\n+34 983420084\nsadilauro@live.it\nDate and place of Birth:\nID Number\nMedical Licence \nLanguages\t09-05-1985. Villaricca (Italy)\n\nY1281863H\n474707061\nItalian (native language)\nSpanish (read, written, spoken)\nEnglish (read, written, spoken)\nPortuguese (read, spoken)\nFrench (read)\n\t\t\nCurrent position (title and company)\tDate (Year)\nVitreo-Retinal consultant in ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl. National Health System.\nVitreo-Retinal consultant in ophthalmology. Instituto Oftalmologico Recoletas. Red Hospitalaria Recoletas. Private practise.\t2017-today\n\n2019-today\n\t\n\t\nEducation (High school, university and postgraduate training > 3 months)\tDate (Year)\nDegree in Medicine and Surgery. University of Neaples 'Federico II”\nResident in Opthalmology. Hospital Clinico Universitario Valladolid\nMaster in Vitreo-Retina. IOBA. University of Valladolid\nFellow of the European Board of Ophthalmology. Paris\nMaster in Research in Ophthalmology. University of Valladolid\t2003-2009\n2012-2016\n2016-2017\n2016\n2012-2013\n\t\nEmployments (company and positions)\tDate (Year)\nResident in Ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl.\nFellow in Vitreo-Retina. IOBA. University of Valladolid\nVitreo-Retinal consultant in ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl. National Health System.\nVitreo-Retinal consultant in ophthalmology. Instituto Oftalmologico Recoletas. Red Hospitalaria Recoletas. \n\t2012-2016\n2016-2017\n2017-today\n\n2019-Today\n\n\n\t\nClinical Research Experience (tasks and role)\tDate (Year)\nAssociated investigator\n\n' FIS PI20/00740: DESARROLLO DE UNA CALCULADORA DE RIESGO DE\nAPARICION DE RETINOPATIA DIABETICA BASADA EN TECNICAS DE IMAGEN MULTIMODAL EN PACIENTES DIABETICOS TIPO 1. Grant by: Ministerio de Ciencia e Innovacion \n\n' (BIO/VA23/14) Estudio clínico multicéntrico y prospectivo para validar dos\nbiomarcadores ubicados en los genes p53 y MDM2 en la predicción de los resultados funcionales de la cirugía del desprendimiento de retina regmatógeno. Grant by: Gerencia Regional de Salud de la Junta de Castilla y León.\n' Estudio multicéntrico, aleatorizado, con enmascaramiento doble, en 2 grupos\nparalelos y de 52 semanas de duración para comparar la eficacia, seguridad e inmunogenicidad de SOK583A1 respecto a Eylea® en pacientes con degeneración macular neovascular asociada a la edad' (CSOK583A12301; N.EUDRA: 2019-004838-41; FASE III). Grant by Hexal AG\n\n' Estudio de fase III, aleatorizado, doble ciego, con grupos paralelos, multicéntrico para comparar la eficacia y la seguridad de QL1205 frente a Lucentis® en pacientes con degeneración macular neovascular asociada a la edad. (EUDRACT: 2018-004486-13). Grant by Qilu Pharmaceutical Co\n\n' Estudio NEUTON: Ensayo clinico en fase IV para evaluar la eficacia de aflibercept en pacientes Naive con Edema MacUlar secundario a Oclusion de Vena CenTral de la Retina (OVCR) en regimen de tratamientO iNdividualizado Treat and Extend (TAE)”, (2014-000975-21). Grant by Fundacion Retinaplus\n\n' Evaluación de la seguridad y bioactividad de anillos de tensión capsular en conejo. Proyecto Procusens. Grant by AJL, S.A.\n\n'Estudio epidemiológico, prospectivo, multicéntrico y abierto\\npara valorar la frecuencia de la conjuntivitis adenovírica diagnosticada mediante el test AdenoPlus®\\nTest en pacientes enfermos de conjuntivitis aguda”\\n. National, multicenter study. Grant by: NICOX.\n\nEuropean multicentric trial: 'Evaluation of clinical outcomes following the use of Systane Hydration in patients with dry eye”. Study Phase 4. Grant by: Alcon Labs'\n\nVLPs Injection and Activation in a Rabbit Model of Uveal Melanoma. Grant by Aura Bioscience\n\nUpdating and characterization of a rabbit model of uveal melanoma. Grant by Aura Bioscience\n\nEnsayo clínico en fase IV para evaluar las variantes genéticas de la vía del VEGF como biomarcadores de eficacia del tratamiento con aflibercept en pacientes con degeneración macular asociada a la edad (DMAE) neovascular. Estudio BIOIMAGE. IMO-AFLI-2013-01\n\nEstudio In-Eye:Ensayo clínico en fase IV, abierto, aleatorizado, de 2 brazos,\nmulticçentrico y de 12 meses de duración, para evaluar la eficacia y seguridad de un régimen de PRN flexible individualizado de 'esperar y extender' versus un régimen PRN según criterios de estabilización mediante evaluaciones mensuales de inyecciones intravítreas de ranibizumab 0,5 mg en pacientes naive con neovascularización coriodea secunaria a la degeneración macular relacionada con la edad. CP: CRFB002AES03T\n\nTREND: Estudio Fase IIIb multicéntrico, randomizado, de 12 meses de\nseguimiento con evaluador de la agudeza visual enmascarado, para evaluar la eficacia y la seguridad de ranibizumab 0.5mg en un régimen de tratar y extender comparado con un régimen mensual, en pacientes con degeneración macular neovascular asociada a la edad. CP: CRFB002A2411 Código Eudra CT:\n2013-002626-23\n\n\n\nPublications\t\n\n2021\n\n\n\n\n2015\n\n\n\n\n2021\n\n\n\n\n\n2021\n\n\n\n\n2015\n\n\n\n\n2015\n\n\n2014\n\n\n\n\n2015-16\n\n\n\n2015\n\n\n2014\n\n\n2014\n\n\n\n\n2014\n\n\n\n\n\n\n\n2014\n\nJose Carlos Pastor; Jimena Rojas; Salvador Pastor-Idoate; Salvatore Di Lauro; Lucia Gonzalez-Buendia; Santiago Delgado-Tirado. Proliferative vitreoretinopathy: A new concept of disease pathogenesis and practical\nconsequences. Progress in Retinal and Eye Research. 51, pp. 125 - 155. 03/2016. DOI: 10.1016/j.preteyeres.2015.07.005\n\n\nLabrador-Velandia S; Alonso-Alonso ML; Di Lauro S; García-Gutierrez MT; Srivastava GK; Pastor JC; Fernandez-Bueno I. Mesenchymal stem cells provide paracrine neuroprotective resources that delay degeneration of co-cultured organotypic neuroretinal cultures.Experimental Eye Research. 185, 17/05/2019. DOI: 10.1016/j.exer.2019.05.011\n\nSalvatore Di Lauro; Maria Teresa Garcia Gutierrez; Ivan Fernandez Bueno. Quantification of pigment epithelium-derived factor (PEDF) in an ex vivo coculture of retinal pigment epithelium cells and neuroretina.\nJournal of Allbiosolution. 2019. ISSN 2605-3535\n\nSonia Labrador Velandia; Salvatore Di Lauro; Alonso-Alonso ML; Tabera Bartolomé S; Srivastava GK; Pastor JC; Fernandez-Bueno I. Biocompatibility of intravitreal injection of human mesenchymal stem cells in immunocompetent rabbits. Graefe's archive for clinical and experimental ophthalmology. 256 - 1, pp. 125 - 134. 01/2018. DOI: 10.1007/s00417-017-3842-3\n\n\nSalvatore Di Lauro, David Rodriguez-Crespo, Manuel J Gayoso, Maria T Garcia-Gutierrez, J Carlos Pastor, Girish K Srivastava, Ivan Fernandez-Bueno. A novel coculture model of porcine central neuroretina explants and retinal pigment epithelium cells. Molecular Vision. 2016 - 22, pp. 243 - 253. 01/2016.\n\nSalvatore Di Lauro. Classifications for Proliferative Vitreoretinopathy ({PVR}): An Analysis of Their Use in Publications over the Last 15 Years. Journal of Ophthalmology. 2016, pp. 1 - 6. 01/2016. DOI: 10.1155/2016/7807596\n\nSalvatore Di Lauro; Rosa Maria Coco; Rosa Maria Sanabria; Enrique Rodriguez de la Rua; Jose Carlos Pastor. Loss of Visual Acuity after Successful Surgery for Macula-On Rhegmatogenous Retinal Detachment in a Prospective Multicentre Study. Journal of Ophthalmology. 2015:821864, 2015. DOI: 10.1155/2015/821864\n\nIvan Fernandez-Bueno; Salvatore Di Lauro; Ivan Alvarez; Jose Carlos Lopez; Maria Teresa Garcia-Gutierrez; Itziar Fernandez; Eva Larra; Jose Carlos Pastor. Safety and Biocompatibility of a New High-Density Polyethylene-Based\nSpherical Integrated Porous Orbital Implant: An Experimental Study in Rabbits. Journal of Ophthalmology. 2015:904096, 2015. DOI: 10.1155/2015/904096\n\nPastor JC; Pastor-Idoate S; Rodríguez-Hernandez I; Rojas J; Fernandez I; Gonzalez-Buendia L; Di Lauro S; Gonzalez-Sarmiento R. Genetics of PVR and RD. Ophthalmologica. 232 - Suppl 1, pp. 28 - 29. 2014\n\nRodriguez-Crespo D; Di Lauro S; Singh AK; Garcia-Gutierrez MT; Garrosa M; Pastor JC; Fernandez-Bueno I; Srivastava GK. Triple-layered mixed co-culture model of RPE cells with neuroretina for evaluating the neuroprotective effects of adipose-MSCs. Cell Tissue Res. 358 - 3, pp. 705 - 716. 2014.\nDOI: 10.1007/s00441-014-1987-5\n\nCarlo De Werra; Salvatore Condurro; Salvatore Tramontano; Mario Perone; Ivana Donzelli; Salvatore Di Lauro; Massimo Di Giuseppe; Rosa Di Micco; Annalisa Pascariello; Antonio Pastore; Giorgio Diamantis; Giuseppe Galloro. Hydatid disease of the liver: thirty years of surgical experience.Chirurgia italiana. 59 - 5, pp. 611 - 636.\n(Italia): 2007. ISSN 0009-4773\n\nChapters in books\n\t\n' Salvador Pastor Idoate; Salvatore Di Lauro; Jose Carlos Pastor Jimeno. PVR: Pathogenesis, Histopathology and Classification. Proliferative Vitreoretinopathy with Small Gauge Vitrectomy. Springer, 2018. ISBN 978-3-319-78445-8\nDOI: 10.1007/978-3-319-78446-5_2. \n\n' Salvatore Di Lauro; Maria Isabel Lopez Galvez. Quistes vítreos en una mujer joven. Problemas diagnósticos en patología retinocoroidea. Sociedad Española de Retina-Vitreo. 2018.\n\n' Salvatore Di Lauro; Salvador Pastor Idoate; Jose Carlos Pastor Jimeno. iOCT in PVR management. OCT Applications in Opthalmology. pp. 1 - 8. INTECH, 2018. DOI: 10.5772/intechopen.78774.\n\n' Rosa Coco Martin; Salvatore Di Lauro; Salvador Pastor Idoate; Jose Carlos Pastor. amponadores, manipuladores y tinciones en la cirugía del traumatismo ocular.Trauma Ocular. Ponencia de la SEO 2018..\n\n' LOPEZ GALVEZ; DI LAURO; CRESPO. OCT angiografia y complicaciones retinianas de la diabetes. PONENCIA SEO 2021, CAPITULO 20. (España): 2021.\n\n' Múltiples desprendimientos neurosensoriales bilaterales en paciente joven. Enfermedades Degenerativas De Retina Y Coroides. SERV 04/2016. \n' González-Buendía L; Di Lauro S; Pastor-Idoate S; Pastor Jimeno JC. Vitreorretinopatía proliferante (VRP) e inflamación: LA INFLAMACIÓN in «INMUNOMODULADORES Y ANTIINFLAMATORIOS: MÁS ALLÁ DE LOS CORTICOIDES. 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