The increasing load of environmental pollutants poses a serious threat over the globe. In this vulnerable situation, it is essential to have alternative sources of medicines, may be from invertebrates. Among invertebrates, although molluscs are known for their consumption as food and ethno‐medicinal use, the importance of these animals is still overlooked. Presently attention has been geared toward molluscs including Achatina fulica which are now considered as one of the most evolutionary successful animals. During the last few decades, researchers are trying to decipher their complex immune system to harvest valuable molecules to treat human diseases. In the present review, the existence of important immunological factors in Achatina is discussed addressing the coagulation system, innate immune molecules, bioactive proteins and lastly the enigmatic C‐reactive proteins.
Part of the book: Organismal and Molecular Malacology
Ferroptosis in recent days has gained high impact due to its implication in inducing several neurological challenges. Impairment of iron homeostasis (mainly surplus iron deposition) is the key reason for the induction of the ferroptotic cell death. This type of programmed cell death in the neurons can trigger neuropathological abnormalities. Ferroptosis has been given clinical importance, where biomedical researchers are working on the pathological detection of ferroptosis and finding clinical ways to arrest it. In this review, we have elucidated the impact of ferroptotic cell death on the pathophysiology of several neurological challenges.
Part of the book: Cell Death and Disease