Description of data used for the analysis.
\r\n\tNanogenerators have emerged as a leading mechanical energy harvesting technology within the last five years, proving their applicability as energy harvesters as well as self-powered active sensors. These biomechanical energy harvesting devices are eco-friendly and pollution-free renewable energy sources.
\r\n\r\n\tThe proposed book should cover the energy conversion mechanisms of triboelectric, piezoelectric, and hybrid generators and their boosting performance strategies. Furthermore, the various strategies adopted so far to improve the performance of various nanogenerators using the theoretical assumptions and experimental analysis can be also described briefly. Ultimately, this book will cover the application of nanogenerators in self-powered sensors & systems and their commercialization.
",isbn:"978-1-80356-255-1",printIsbn:"978-1-80356-254-4",pdfIsbn:"978-1-80356-256-8",doi:null,price:0,priceEur:0,priceUsd:0,slug:null,numberOfPages:0,isOpenForSubmission:!1,isSalesforceBook:!1,isNomenclature:!1,hash:"d52edc8b54e3451fe151b38cb4c9aee9",bookSignature:"Dr. Bhaskar Dudem and Dr. Vivekananthan Venkateswaran",publishedDate:null,coverURL:"https://cdn.intechopen.com/books/images_new/11465.jpg",keywords:"Surface Modification, Charge Transfer, Charge Accumulation, High Performance, Hybridization, Composite Films, Self-Powered, Pressure Sensor, Tactile Sensor, Blue Energy, Triboelectric, Piezoelectric",numberOfDownloads:null,numberOfWosCitations:0,numberOfCrossrefCitations:null,numberOfDimensionsCitations:null,numberOfTotalCitations:null,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"February 10th 2022",dateEndSecondStepPublish:"April 14th 2022",dateEndThirdStepPublish:"June 13th 2022",dateEndFourthStepPublish:"September 1st 2022",dateEndFifthStepPublish:"October 31st 2022",dateConfirmationOfParticipation:null,remainingDaysToSecondStep:"2 months",secondStepPassed:!0,areRegistrationsClosed:!0,currentStepOfPublishingProcess:4,editedByType:null,kuFlag:!1,biosketch:"An active researcher in harnessing the ubiquitously available biomechanical energies to power portable electronics, with over 1000 citations, and a high h index(20). Dr. Dudem was awarded an ATI Research Laurette award 2019/20 for his high-impact paper published in Nano Energy, and his research activities have also been featured in most-famous news websites including MSN, Nanowerk, Phys.org, and Medical Design Briefs.",coeditorOneBiosketch:"An active researcher in energy harvesting using triboelectric and piezoelectric effects, graduated from Anna University, member of the Royal Society of Chemistry, and winner of the President Award for Outstanding Achievement in research and academics.",coeditorTwoBiosketch:null,coeditorThreeBiosketch:null,coeditorFourBiosketch:null,coeditorFiveBiosketch:null,editors:[{id:"315573",title:"Dr.",name:"Bhaskar",middleName:null,surname:"Dudem",slug:"bhaskar-dudem",fullName:"Bhaskar Dudem",profilePictureURL:"https://mts.intechopen.com/storage/users/315573/images/system/315573.png",biography:"Bhaskar Dudem is currently working as a Post-Doctoral Research Fellow (from Oct 2019) at the Advanced Technology Institute (ATI), University of Surrey, England, UK. He received the Master of Technology (MTech., 2012) from the Department of Materials Science and Engineering, Indian Institute of Technology (IIT) Kanpur, India. Afterwards, he was as a teaching faculty member at K.L. University, India (2012–2014). In Aug 2018, he received a PhD degree from the Department of Electronics and Radio Engineering, Institute for Wearable Convergence Electronics (IWCE), Kyung Hee University, South Korea. He also worked at the same institute as a Post-Doc for a year (Sep 2018–Sep 2019). His research interests include wearable and flexible piezo/triboelectric nanogenerators for energy harvesting and sensing applications, anti-reflection coatings, solar, and hybrid energy cells, resulting in more than 30 works published in reputed peer-reviewed international journals.",institutionString:"University of Surrey",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"0",totalChapterViews:"0",totalEditedBooks:"0",institution:{name:"University of Surrey",institutionURL:null,country:{name:"United Kingdom"}}}],coeditorOne:{id:"451991",title:"Dr.",name:"Vivekananthan",middleName:null,surname:"Venkateswaran",slug:"vivekananthan-venkateswaran",fullName:"Vivekananthan Venkateswaran",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00003Le2O7QAJ/Profile_Picture_1641976792394",biography:"Venkateswaran Vivekananthan is currently a Research Associate in Advanced Technology Institute (ATI), University Surrey. Prior to joining in University of Surrey, he worked as a Post-Doctoral Associate in the Faculty of Applied Energy Systems (Major in Mechatronics Engineering) at Jeju National University, South Korea. He was a recipient of NRF Creative Challenge Support award as Principal-Investigator with a project funding worth of (USD 45,000/ year). He received his PhD degree in Feb 2020 with President award for outstanding in research and academics. His research focuses on energy harvesting using triboelectric & piezoelectric nanogenerators for self-powered sensor systems.",institutionString:"University of Surrey",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"0",totalChapterViews:"0",totalEditedBooks:"0",institution:{name:"University of Surrey",institutionURL:null,country:{name:"United Kingdom"}}},coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"17",title:"Nanotechnology and Nanomaterials",slug:"nanotechnology-and-nanomaterials"}],chapters:null,productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"},personalPublishingAssistant:{id:"444312",firstName:"Sara",lastName:"Tikel",middleName:null,title:"Ms.",imageUrl:"https://mts.intechopen.com/storage/users/444312/images/20015_n.jpg",email:"sara.t@intechopen.com",biography:"As an Author Service Manager, my responsibilities include monitoring and facilitating all publishing activities for authors and editors. From chapter submission and review to approval and revision, copyediting and design, until final publication, I work closely with authors and editors to ensure a simple and easy publishing process. I maintain constant and effective communication with authors, editors and reviewers, which allows for a level of personal support that enables contributors to fully commit and concentrate on the chapters they are writing, editing, or reviewing. I assist authors in the preparation of their full chapter submissions and track important deadlines and ensure they are met. I help to coordinate internal processes such as linguistic review and monitor the technical aspects of the process. As an ASM I am also involved in the acquisition of editors. Whether that be identifying an exceptional author and proposing an editorship collaboration, or contacting researchers who would like the opportunity to work with IntechOpen, I establish and help manage author and editor acquisition and contact."}},relatedBooks:[{type:"book",id:"5884",title:"Unraveling the Safety Profile of Nanoscale Particles and Materials",subtitle:"From Biomedical to Environmental Applications",isOpenForSubmission:!1,hash:"5e5811aa0f15ab9d8b6a235e8408875d",slug:"unraveling-the-safety-profile-of-nanoscale-particles-and-materials-from-biomedical-to-environmental-applications",bookSignature:"Andreia C. Gomes and Marisa P. Sarria",coverURL:"https://cdn.intechopen.com/books/images_new/5884.jpg",editedByType:"Edited by",editors:[{id:"146466",title:"Prof.",name:"Andreia",surname:"Ferreira de Castro Gomes",slug:"andreia-ferreira-de-castro-gomes",fullName:"Andreia Ferreira de Castro Gomes"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"7325",title:"Nanostructures in Energy Generation, Transmission and Storage",subtitle:null,isOpenForSubmission:!1,hash:"8e49924dd2c3e28c82fdc115ce04f925",slug:"nanostructures-in-energy-generation-transmission-and-storage",bookSignature:"Yanina Fedorenko",coverURL:"https://cdn.intechopen.com/books/images_new/7325.jpg",editedByType:"Edited by",editors:[{id:"199149",title:"Dr.",name:"Yanina",surname:"Fedorenko",slug:"yanina-fedorenko",fullName:"Yanina Fedorenko"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9230",title:"Smart Nanosystems for Biomedicine, Optoelectronics and Catalysis",subtitle:null,isOpenForSubmission:!1,hash:"1d1af591d87490c9ad728a1352e62d96",slug:"smart-nanosystems-for-biomedicine-optoelectronics-and-catalysis",bookSignature:"Tatyana Shabatina and Vladimir Bochenkov",coverURL:"https://cdn.intechopen.com/books/images_new/9230.jpg",editedByType:"Edited by",editors:[{id:"237988",title:"Prof.",name:"Tatyana",surname:"Shabatina",slug:"tatyana-shabatina",fullName:"Tatyana Shabatina"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9322",title:"Hybrid Nanomaterials",subtitle:"Flexible Electronics Materials",isOpenForSubmission:!1,hash:"beff6cce44f54582ee8a828759d24f19",slug:"hybrid-nanomaterials-flexible-electronics-materials",bookSignature:"Rafael Vargas-Bernal, Peng He and Shuye Zhang",coverURL:"https://cdn.intechopen.com/books/images_new/9322.jpg",editedByType:"Edited by",editors:[{id:"182114",title:"D.Sc.",name:"Rafael",surname:"Vargas-Bernal",slug:"rafael-vargas-bernal",fullName:"Rafael Vargas-Bernal"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10463",title:"Nanomechanics",subtitle:"Theory and Application",isOpenForSubmission:!1,hash:"c0c14ad42c145ac8720b4ab4d666f395",slug:"nanomechanics-theory-and-application",bookSignature:"Alexander V. Vakhrushev",coverURL:"https://cdn.intechopen.com/books/images_new/10463.jpg",editedByType:"Edited by",editors:[{id:"140718",title:"Prof.",name:"Alexander V.",surname:"Vakhrushev",slug:"alexander-v.-vakhrushev",fullName:"Alexander V. Vakhrushev"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"1591",title:"Infrared Spectroscopy",subtitle:"Materials Science, Engineering and Technology",isOpenForSubmission:!1,hash:"99b4b7b71a8caeb693ed762b40b017f4",slug:"infrared-spectroscopy-materials-science-engineering-and-technology",bookSignature:"Theophile Theophanides",coverURL:"https://cdn.intechopen.com/books/images_new/1591.jpg",editedByType:"Edited by",editors:[{id:"37194",title:"Dr.",name:"Theophile",surname:"Theophanides",slug:"theophile-theophanides",fullName:"Theophile Theophanides"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3161",title:"Frontiers in Guided Wave Optics and Optoelectronics",subtitle:null,isOpenForSubmission:!1,hash:"deb44e9c99f82bbce1083abea743146c",slug:"frontiers-in-guided-wave-optics-and-optoelectronics",bookSignature:"Bishnu Pal",coverURL:"https://cdn.intechopen.com/books/images_new/3161.jpg",editedByType:"Edited by",editors:[{id:"4782",title:"Prof.",name:"Bishnu",surname:"Pal",slug:"bishnu-pal",fullName:"Bishnu Pal"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3092",title:"Anopheles mosquitoes",subtitle:"New insights into malaria vectors",isOpenForSubmission:!1,hash:"c9e622485316d5e296288bf24d2b0d64",slug:"anopheles-mosquitoes-new-insights-into-malaria-vectors",bookSignature:"Sylvie Manguin",coverURL:"https://cdn.intechopen.com/books/images_new/3092.jpg",editedByType:"Edited by",editors:[{id:"50017",title:"Prof.",name:"Sylvie",surname:"Manguin",slug:"sylvie-manguin",fullName:"Sylvie Manguin"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"371",title:"Abiotic Stress in Plants",subtitle:"Mechanisms and Adaptations",isOpenForSubmission:!1,hash:"588466f487e307619849d72389178a74",slug:"abiotic-stress-in-plants-mechanisms-and-adaptations",bookSignature:"Arun Shanker and B. Venkateswarlu",coverURL:"https://cdn.intechopen.com/books/images_new/371.jpg",editedByType:"Edited by",editors:[{id:"58592",title:"Dr.",name:"Arun",surname:"Shanker",slug:"arun-shanker",fullName:"Arun Shanker"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"72",title:"Ionic Liquids",subtitle:"Theory, Properties, New Approaches",isOpenForSubmission:!1,hash:"d94ffa3cfa10505e3b1d676d46fcd3f5",slug:"ionic-liquids-theory-properties-new-approaches",bookSignature:"Alexander Kokorin",coverURL:"https://cdn.intechopen.com/books/images_new/72.jpg",editedByType:"Edited by",editors:[{id:"19816",title:"Prof.",name:"Alexander",surname:"Kokorin",slug:"alexander-kokorin",fullName:"Alexander Kokorin"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}]},chapter:{item:{type:"chapter",id:"77903",title:"Cellulose as a Natural Emulsifier: From Nanocelluloses to Macromolecules",doi:"10.5772/intechopen.99139",slug:"cellulose-as-a-natural-emulsifier-from-nanocelluloses-to-macromolecules",body:'Every year, hundred billion tons of cellulose are produced by nature from various biomass sources, making this biopolymer an ultimate platform for developing sustainable applications on an industrial scale [1]. The increased environmental awareness due to global climate changes has pushed cellulose science to advance rapidly, and thus cellulose is expected to continue playing a central role in the emergent bio-economies and biorefineries. Cellulose extraction and purification rely on fairly simple, scalable, and efficient isolation techniques, and cellulose can be further modified and shaped into different colloidal and macroscopic forms, showing very different features [2, 3, 4, 5].
Emulsions are among the most important colloids in everyday life, and have multiple uses, from technical applications, such as paints and coatings, to life science applications, such as foods, pharmaceuticals, and cosmetics. Emulsions can encapsulate and protect sensitive ingredients, adjust appearance, taste and sensorial properties, and facilitate application, spreading and drying. They can also serve as an intermediator for efficient oil extraction, polymerization reactions, and the production of microcapsules and lightweight foams [6]. Their structural and functional properties are vast and therefore, the emulsifiers and stabilizers must be carefully selected according to the needs. With the growing global demand for sustainable and “clean-label” products, industries are actively seeking to replace synthetic emulsifiers by new alternatives. Finding natural ingredients, with minimal modification requirements (without compromising environment and human health) and still being capable of achieving a competitive performance to the optimized synthetic options is highly desirable but challenging. In this respect, cellulose has the potential to become a key star player in emulsion systems. In addition to its natural, non-toxic, biodegradable, and renewable nature, it is also a versatile source of natural emulsifiers. From cellulose derivatives, used since the early 20th century, to the more recently explored native forms of cellulose, including nanocelluloses, and the native cellulose itself, either molecular or in the form of polymeric particles and microgels, all its different morphological forms have shown an intrinsic amphiphilic character by self-assembling at oil–water interfaces.
Emulsions are multiphasic systems of at least three main components, the oil phase, the water phase, and the emulsifier. One of the phases is dispersed into the other in the form of droplets that are stabilized by a key compound, an emulsifier. Depending on the dispersed phase, we can have either oil-in-water (o/w) or water-in-oil (w/o) emulsions, and the type of emulsion formed mainly depends on the solubility properties of the emulsifier. According to Bancroft’s rule, o/w emulsions are formed when the emulsifier has a preference for water whereas the opposite applies for w/o emulsions [7]. When an emulsion is formed, a large interfacial area is created between the two phases, generating an increased energy in relation to the interfacial tension between oil and water. Therefore, emulsions seek to minimize the energy used to create such large interfacial area and break down over time by the combination of different instability mechanisms, such as, creaming, flocculation, coalescence and Ostwald ripening [7]. The role of the emulsifier is to reduce the interfacial tension and form a “protective layer” through its adsorption on the droplets surface, thus facilitating not only the formation of the droplets but also preventing/minimizing their re-association. Amphiphilic molecules and insoluble particles have both been employed as emulsifiers (Figure 1). Small surfactant molecules are usually good emulsifiers. Nevertheless, they are often not particularly well suited to provide long-term stability; this is because they are in dynamic equilibrium with the bulk medium. In this case, often, a stabilizer is required to achieve sufficient kinetic stability for the required shelf-life of a certain product. Polymers are often applied as stabilizers in oil-in-water (o/w) emulsions, and they can act either via the reinforcement of the stabilizing layer, co-acting with the emulsifier at the interface, or via the viscosity enhancement of the continuous phase, thus reducing droplet mobility [8]. Certain amphiphilic polymers and particles may act as both emulsifiers and stabilizers. Good examples are surface-active polysaccharides, such as gum Arabic, pectin, galactomannans and modified starches and celluloses [8, 9, 10, 11]. These polymers provide strong steric repulsions driven by the entropic penalty when polymer segments from two droplets start to entangle, since conformational rearrangements are hindered due to their high molecular weight [12].
Emulsifiers: Surfactants, polymers and particles. Differences in scaling are not considered.
Another type of stabilization is provided by insoluble particles, often called Pickering stabilization; rigid particles, Janus particles and microgels, have been described as Pickering emulsifiers [13, 14, 15]. The amphiphilicity of a typical Pickering emulsifier (rigid particles) is usually described in terms of surface wettability, which is measured by the three-phase contact angle of a particle adsorbed at an oil–water interface. Both o/w and w/o emulsions can be formed depending on the particle wettability and whether the particles are predominantly hydrophilic or hydrophobic [13]. In agreement with Bancroft’s rule, the interface tends to bend towards the more poorly wetted liquid, and this becomes the dispersed phase. Pickering particles adsorb irreversibly at the oil–water interfaces due to the high-binding energy per particle, forming an effective mechanical barrier against coalescence; they may also inhibit lipid oxidation due to the thick interfacial layers formed [10, 11]. This is an important feature in what concerns food and pharmaceutical applications where polyunsaturated lipids are involved. Their double bonds are prone to oxidation leading to the deterioration of the products by the formation of rancid flavors and, eventually, toxic by-products [16]. The most widely used bioparticles are derived from biopolymers, such as cellulose, chitin and chitosan, starch and modified starches, lignin and proteins [17, 18, 19, 20, 21]. Bioparticles may vary widely in shape, size, aspect ratio and morphology, implying that their mechanistic behavior considerably deviates from that of both the solid sphere and the flexible polymer [22]. Nevertheless, particles with an irregular shape and higher aspect ratios have been found to have a greater ability in stabilizing emulsions and foams (and at lower concentrations) compared to synthetic particles of spherical shape [19].
A special type of particles that display some similarities to surfactants and polymers are known as Janus particles. These are amphiphilic particles, composed of two or more regions with distinct physicochemical properties, that can self-assemble in bulk media and readily adsorb to fluid interfaces, remarkably lowering the interfacial tension; for this reason, they are also called “colloidal surfactants” [14, 23, 24]. They can be synthesized in geometrically different shapes and chemical compositions with high uniformity and precision [14]. Polysaccharides, such as, alginates, chitosan, pectin, cellulose and heparin, have been used to produce bio-based Janus particles [25, 26].
Another interesting type of emulsifying particles are microgels, which are soft deformable gel-like particles made up of aggregated or cross-linked polymer networks [22]. These microgels can swell in aqueous solvents and rearrange at the oil–water interface, resulting in thick and mechanically resilient layers. Owing to the amphiphilic character of their polymeric constituents, most microgels are inherently surface active at oil–water and air-water interfaces and, as rigid particles, they also irreversibly adsorb at the interfaces [22]. Synthetic microgels offer an additional feature that arises as a direct consequence of their combined polymeric and particulate character. They have the potential to effectively stabilize water-in-water emulsions, which are mixed solutions of thermodynamically incompatible polymers, producing two immiscible aqueous phases, and where the effective thickness of the interface is defined on a length scale considerably greater than the molecular dimensions of a conventional emulsifier [22, 27]. However, microgels based on physical cross-linking of biopolymers are rather novel and much of their behavior at interfaces remains unclear [15]. Two examples of natural ingredients that exhibit microgel-like characteristics are casein micelles (in their native form) and whey proteins and gelatinized starch granules (upon heat treatment). However, in order to mimic the special features of the synthetic microgels, these traditional food-grade microgels need more pronounced long-term structural stability under conventional processing and storage conditions, which typically requires the introduction of additional covalent cross-links within the aggregated biopolymer-based entity [22].
Cellulose is a polysaccharide composed of glucose monomers, the anhydroglucose units (AGUs), linked by β -(1–4) glycosidic bonds. These β-linked AGUs adopt the 4C1 chain conformation, which is the conformation with the lowest free energy of the molecule. Consequently, the three polar hydroxyl groups in each AGU are located on the equatorial positions of the rings, and the hydrogen atoms of the non-polar C–H bonds are located on the axial positions [1]. This structural anisotropy is what gives cellulose its amphiphilic nature [28]. Due to the large number of hydroxyl groups within a cellulose molecule, both intra- and intermolecular hydrogen bonding occur and various types of supramolecular semi-crystalline structures can be formed. It is believed that intramolecular hydrogen bonding is responsible for the single-chain conformation and stiffness, while the intermolecular hydrogen bonding would be responsible for the sheet-like arrangement of the native polymer [1]. However, the stacking of these sheets into the three-dimensional crystalline supramolecular structures must involve hydrophobic interactions, as it was shown trough molecular dynamic simulations, and moreover was observed, many years ago, in native cellulose biosynthesis [1, 29, 30].
Hydrophobic interactions between cellulose molecules make, in combination with favorable packing conditions (and thus a low energy) in the crystalline state, cellulose insoluble in water [31]. Solubility can be achieved by ionizing cellulose, which occurs at extreme pH’s. Solubility in water can also be aided by addition of co-solutes that weaken hydrophobic interactions. Derivatization of cellulose is also found to generally enhance solubility strongly, which can be referred to packing constraints in the solid state. Thus, to make cellulose soluble in aqueous solutions, the crystalline packing has to be disrupted, and this can be achieved, for example, by chemical modifications via etherification reactions in alkaline media, resulting in water-soluble cellulose ethers [32, 33]. These cellulose derivatives keep the amphiphilic properties of cellulose, as can be seen from their association with surfactants and their adsorption at the air-water and oil–water interfaces [34, 35, 36, 37, 38, 39].
A fairly simple way of converting cellulose into a versatile class of new materials is through a dissolution-regeneration process. The regeneration of cellulose occurs when a coagulant (“anti-solvent”) gets in contact with a cellulose solution or dope, leading to a solvent exchange and subsequent aggregation of the cellulose chains. The organization of the molecules in the regenerated materials (e.g., fibers, films, foams, particles) and their properties are strongly influenced by the dissolution state of cellulose (molecular cellulose, partially dissolved, crystalline or amorphous aggregates), as a well as the nature of the coagulant used [40, 41].
Cellulose can also be shaped into micro- and nanoparticles of different colloidal structure. Acid or mechanical treatments are usually applied to deconstruct the cellulose fibers into crystalline or semi-crystalline nanocelluloses [20, 42, 43, 44]. Partial decomposition of cellulose fibers, by acid treatment and cellulase-catalyzed hydrolysis, yields powdery microcrystalline cellulose (MCC), such as commercial Avicel®, with DP values between 150 and 300 [45]. Avicel® still contains both amorphous and crystalline portions. On the other hand, nanocrystalline cellulose (NCC) is obtained by strong acid hydrolysis. During the chemical process, the more readily accessible amorphous regions are completely disrupted deliberating rod-like crystal sections, whose sizes are dependent on the time and temperature of the reaction. The dimensions of the isolated NCC are also found to be strongly influenced by the degree of crystallinity of cellulose, which, in turn, is dependent on the natural source. Cotton, wood and Avicel® usually yield highly crystalline nanorods (90% crystallinity) with a narrow distribution of sizes (5–10 nm in width and 100–300 nm in length), whereas sources, such as tunicin (extracted from the tunicates), bacteria and algae, yield crystals with higher polydispersity and larger dimensions [42]. NCC forms stable suspensions in water by application of a mechanical force, typically sonication. Its surface properties are determined by the mineral acid and the reaction conditions used during its extraction. NCC prepared with hydrochloric acid (HCl) is weakly negatively charged, while it exhibits a strong repulsive character if prepared with sulfuric acid (H2SO4), since approximately one tenth of the glucose units is functionalized with the anionic sulfate ester groups. Thus, NCC prepared with H2SO4 give suspensions with higher colloidal stability than NCC prepared with HCl.
Micro- and nanofibrillated (MFC/NFC) celluloses are obtained by extruding wood pulp suspensions trough mechanical devices (high-pressure homogenizers), which results in fiber delamination and deliberation of the fibrils, usually being tens of nanometers wide and lengths ranging from several nanometers to several micrometers (i.e., 5–60 nm in width and 100 nm to several micrometers in length) [42]. This type of nanocelluloses are usually less crystalline than NCC, since they still own part of the amorphous domains, and have higher aspect ratios [5, 46]. In aqueous solutions, the fiber-like morphology and high aspect ratio, typically drive gel-like behavior due to entanglements between the microfibrils.
Several researchers have demonstrated the ability of cellulose particles to self-assemble at oil–water interfaces and to stabilize o/w emulsions without the aid of classical surfactants [47, 48, 49]. It is believed that the amphiphilic character of nanocellulose resides in its crystalline organization at the elementary “brick” level, and thus, cellulose nanocrystals have both hydrophilic and hydrophobic edges that are preferentially wetted by water and oil phases, respectively [49]. The wettability properties of cellulose particles may be tuned by surface hydrophobization, due to the presence of many reactive hydroxyl groups, and w/o emulsions can be formed [50, 51, 52]. Most of the particles from biological origins, such as cellulose, chitosan, or starch, show an irregular shape and are polydisperse in size and morphology. However, this structural anisotropy may be very beneficial for emulsion formation and stability. Particles with high aspect ratios are capable of stabilizing biphasic systems at lower concentrations compared to systems containing spherical particles [53]. Particles with such a well-defined shape are usually derived from inorganic materials, like silica and these have been extensively studied because of their availability in different sizes with narrow size distributions and chemical surface tunability. However, their lack of biocompatibility and biodegradability restricts their use in food and pharmaceutical applications [54]. For this reason, the study and characterization of materials from biological origins have gained increasing attention, and many efforts have been made in the food and pharmaceutical industries in order to develop new food-grade particles [19, 55]. It was early noticed that MCC particles have the ability to stabilize conventional o/w emulsions, and multiple emulsions systems of w/o/w type, with the aid of a hydrophobic surfactant for the stabilization of the internal w/o interface [56, 57]. These MCC particles form a network around the emulsified oil droplets that provides a mechanical barrier against coalescence, and, beyond that, the non-adsorbed particles may act as thickener agents in the continuous aqueous phase. MCC particles have also the ability to reduce lipid oxidation, one of the major concerns among food manufacturers due to its negative effects on food quality [55]. More recently, nanocelluloses, such as MFC/NFC and NCC, have been increasingly in focus for having a better performance than MCC, owing their smaller sizes and more regular shapes [58]. NCCs with low aspect ratios (shorter) have a dense organization at the interface and cover better the oil surface, while NCCs with high aspect ratios (longer) typically form a network around the droplet with relatively low coverage. Therefore, shorter NCCs have better emulsification efficiency and long-term stability, since higher droplet coverage usually means smaller droplet size [59, 60]. On the other hand, long nanofibrils (NFC) with a high aspect ratio also tend to form bigger droplets resultant from a lower surface coverage, but the fibers protrude in the continuous phase forming a strong network that is able to physically hinder droplet coalescence [59]. As mentioned, the colloidal stability of NCC is controlled by their surface charge resulting from the acid hydrolysis with various acids (e.g., H2SO4 or HCl). The higher the charge density the better their colloidal stability, but their ability to efficiently stabilize emulsions is reduced. Thus, the anionic charges on the surface of the nanocrystals control their tendency to be dispersed in water in relation to being adsorbed at the oil–water interface and, therefore, the particle polarity must be confined to a limited range. A surface charge density lower than ca. 0.03 e/nm2 is ideal for the effectiveness of NCC as an emulsifier and stabilizer, usually achieved by HCl hydrolysis. NCC with sulfate groups, resultant from the hydrolysis with H2SO4, possess a high surface charge density (e.g., 0.123 e/nm2), and the charges may undergo desulfation or may be screened by salt addition, to tune their amphiphilicity [49, 61]. Nanocellulose-stabilized emulsions are generally thermally stable, but in the presence of charges their stability against pH and ionic strength may decrease [58, 62]. NCC are able to form stable o/w high internal phase emulsions (HIPEs) containing volume fractions of oil as high as 0.9, at very low NCC concentrations (< 0.1 wt.%) [61]. Hydrophobized nanocellulose has been also explored to form w/o HIPEs [51]. Double emulsions of both o/w/o and w/o/w have been prepared by using a combination of native and hydrophobized NCC and NFC [63, 64]. Apart from the outstanding physical stability against coalescence, nanocelluloses also afford oxidative stability and lipid digestion control due to the dense interfacial layer formed [60].
Cellulose derivatives produced by etherification reactions are generally water-soluble and surface-active. Therefore, cellulose ethers are a major class of commercially important water-soluble polymers, from construction products, ceramics, and paints to foods, cosmetics, and pharmaceuticals [32, 33, 65, 66]. Cellulose ethers are commonly made by reacting alkali cellulose with the appropriate reagents to substitute the hydroxyl groups of the AGU monomers by either alkyl, hydroxyalkyl or carboxyalkyl groups [66]. Methyl cellulose (MC), ethyl cellulose (EC), hydroxyethyl cellulose (HEC), hydroxypropyl cellulose (HPC), and their derivatives, are common products of those reactions. Their functionality and solubility in water depend on the type of substituent, degree and pattern of substitution, and molecular weight [33, 67]. The non-ionic cellulose ethers, such as, MC, HPMC and EHEC and their hydrophobically modified versions, have been mostly used to produce o/w emulsions due to their water-solubility [68, 69, 70, 71], but EC can be used to stabilize w/o emulsions [72]; this change-over from MC to EC illustrates the subtle role of polarity and illustrates the applicability of Bancroft’s rule. The emulsion stabilization due to cellulose ethers is the result of the combined effects of: a) reduction of the interfacial tension, arising from the balance between polar and non-polar groups; b) adsorption of thick layers, forming a physical barrier with strong steric repulsion; and c) the viscosity increase of the continuous phase, constraining droplet dynamics [7, 71, 73]. Cellulose derivatives often show a dual effect, as stabilizing and emulsifying agents [73]. However, carboxymethyl cellulose (CMC) which is an anionic polymer, cannot efficiently stabilize emulsions by itself due to its highly polar character. However, it can assist emulsion stabilization by controlling the viscosity of the continuous medium [5, 16]. In general, cellulose ethers provide good stability against droplets aggregation due to the strong steric repulsions between the adsorbed polymer layers of two approaching droplets, and due to the increased viscosity of the systems. One of the main advantages of using non-ionic polysaccharides, such as the cellulose ethers in this specific case, is their high stability against environmental stresses, such as, pH, ionic strength, and temperature. This is particularly important in food and pharmaceutical applications, where complex environments are encountered. Cellulose ethers also provide good oxidative stability to the core materials and delay lipid digestion of o/w emulsions, provided that the physical barrier and thickened aqueous phase slows down the diffusion of pro-oxidants and lipases [71, 74]. Lipid digestion is even further reduced using cellulose ethers when compared to calcium-caseinate, a common food emulsifier. Additionally, the thermo-gelling ability of cellulose ethers, in particular HMC, makes it possible to obtain emulsions with high consistency during gastric digestion, contributing to slow down the gastric digestion and increase fullness and satiety perceptions [71].
The behavior of molecularly dissolved cellulose at interfaces is expected to resemble that of typical cellulose derivatives or any semiflexible amphiphilic polymer that shows interfacial activity, i.e., the tendency to adsorb at oil–water interfaces and reduce the free energy between the two phases. However, due to its dissolution limitations, the properties of molecularly dissolved cellulose and its potential in emulsions formation and stability are clearly much less explored. Nevertheless, recent studies have confirmed the stated hypothesis. Molecular dynamics simulations indicate that molecularly dispersed cellulose gradually assembles at the oil–water interface eventually surrounding the oil droplet [75]. Experimentally, molecular cellulose dissolved in H3PO4 (aq.) was found to adsorb at the oil–water interface and decrease the interfacial tension (IFT) between the two phases (Figure 2).
Effect of dissolved cellulose on the interfacial tension oil-aqueous medium.
The decrease in IFT is similar in magnitude to that of the non-ionic cellulose derivatives MC and HPMC, for the same polymer concentration (0.1 wt.%) and same type of oil (liquid paraffin) [34]. Yet, cellulose-stabilized emulsions formed in H3PO4 (aq.) were found to be short-lived, as oil was separating from the emulsions and floating to the top within 24 h. However, by subsequently adding water to the dispersions during emulsification, the properties of the emulsions changed dramatically, and there was no evidence of oil separation over one year of storage (Figure 3). This effect was attributed to a decrease in cellulose solvency in H3PO4 (aq.) by the addition of an anti-solvent (water), which promoted a greater affinity for the oil–water interface, leading to the outstanding stability against macroscopic phase separation of the oil.
Two step emulsification procedure for cellulose dissolved in phosphoric acid solvent.
There are two ways of using native cellulose to stabilize o/w emulsions without the need of further modifications. One, is by following the dissolution-regeneration-emulsification approach, resulting in Pickering emulsions of solid or soft cellulose particles (microgels), since the oil is either dispersed in a water suspension of cellulose particles or in a water suspension of cellulose microgels, respectively [76, 77, 78, 79, 80, 81, 82, 83]. Another way, is to follow the dissolution-emulsification-(“in situ”)regeneration approach, where the oil is directly dispersed in the cellulose solution, and regeneration takes place at the oil–water interface (“in situ”) [34, 84]. This way, the oil droplets seem to be stabilized by a “cellulose film” with a smooth appearance, contrasting with the rough networks and particulate appearances of Pickering emulsions (Figure 4) [7, 84]. Another fundamental difference between the two described approaches is related to the existence of dissolved cellulose during the oil emulsification, which acts as a polymeric surfactant by decreasing the IFT, and possibly contributing for a reduction in droplet size. Overall, the emulsions produced by both methods display very good stability against droplet coalescence which can be referred to the irreversible adsorption of cellulose onto the droplet surfaces [34, 78, 79, 85]. Soft cellulose microgels also impart an outstanding stability against flocculation because of the thick viscoelastic layers formed at the interface [15]. The mechanism behind droplet stabilization in emulsions prepared with cellulose particles is similar to that operating for nanocelluloses as described above, i.e., a combination of Pickering adsorption and network stabilization, often showing gel-like characteristics upon a concentration increase of cellulose [79, 82, 83, 84].
Different morphologies of cellulose-stabilized emulsions. Particle-stabilized emulsions by longer NCC (bacterial cellulose) (a), shorter NCC (b), and regenerated cellulose (dissolution-regeneration-emulsification approach) (d). Emulsions prepared from molecular solutions of cellulose (dissolution-emulsification-”in-situ” regeneration approach) (c and e). Reprinted (adapted) with permission from Ref. [
Moreover, the resulting emulsions are remarkably stable against environmental changes, such as, pH, ionic strength, and temperature, which makes them good candidates for target delivering [80, 82, 86]. Cellulose regenerated particles have also been shown to improve the physical stability of emulsions stabilized by sodium-caseinate, a milk-protein commonly used as a food emulsifier, promoting adsorption of the protein and thickening the continuous phase [87]. Very little has been done regarding the stabilization of w/o emulsions since cellulose particles are better wetted by water than oil. However, it has been suggested that the presence of a water–oil interface when regenerating cellulose affects the conformation of the cellulose molecules and so the way they reassemble. Therefore w/o emulsions are possible to form, but they have poorer stability compared to o/w emulsions [78]. More recently, a “hydrophobic” cellulose microgel was developed to stabilize w/o emulsions, by coagulating cellulose in the presence of a coagulant and sunflower oil [88]. The resultant microgels were more easily dispersed in oil than water, and stable emulsions w/o emulsions were formed. The simplicity and versatility of the dissolution-regeneration approaches open many new possibilities for the functionalization of cellulose and its applicability in both o/w and w/o emulsions.
The list of emulsion formulations having a remarkable impact in our lives is vast, and therefore, it is not surprising that natural molecules have been emerging as important players to partially or completely replace the available non-sustainable options. The future leading role of cellulose as an effective stabilizing agent is unquestionable and opens a new era of sustainable, biocompatible, and value-added functional materials. Surfactant-free emulsions have recently been developed using all forms of cellulose (crystalline, fibrillated, molecular and regenerated), providing a strong support for the vision of cellulose as an amphiphilic molecule, capable of acting as a polymeric surfactant and a Pickering stabilizer. Structural differences and mechanisms of emulsion stabilization between the different cellulose forms have been presented in this chapter. In general, and given the right conditions, cellulose coatings are a powerful mechanical barrier against coalescence, lipid oxidation and lipid digestion. Non-adsorbed cellulose forms a 3D network in the continuous phase, that constrains droplet movements and enhances kinetic stability. The colloidal assembly of cellulose particles when liquid interfaces of notably different polarities are present might serve as a template for the synthesis of new functional microcapsules. The dissolution-regeneration process is highlighted as an important approach of making cellulose-based emulsions, whose hydrophilic–lipophilic balance can be simply tuned by playing with solvent quality and regeneration coagulant(s). Furthermore, the exceptional stability against environmental stresses (pH, ionic strength and temperature) makes the cellulose regenerated coatings potential candidates for target delivery in complex conditions.
This research was funded by the Swedish Research Council (Vetenskapsrådet), grant number 2015-04290. Bruno Medronho acknowledges the financial support from FCT via the projects PTDC/ASP-SIL/30619/2017, UIDB/05183/2020, and the researcher grant IF/01005/2014. Björn Lindman acknowledges the support from the Coimbra Chemistry Centre (CQC), funded by FCT through the Project UID/QUI/00313/2020. The authors also acknowledge the support from Treesearch.se.
The authors declare no conflict of interest.
The United Nations World Urbanization Prospects shows that in 2017, 4.1 billion people were living in urban areas. This indicates that more than half the world population (55%) lived in urban areas. In this context, India’s urbanization is much slower than many developing countries and even its peers such as China, Brazil, and Russia. The latest Census data shows that the percentage of India’s urbanization was 31.15% in 2011. On the other hand, China (or Brazil or Russia) has experienced about 49.2% (or 84.3% or 73.7%) urbanization rate in 2010. The reluctant urbanization in India can be because of a lack of governmental supportive policies or challenges in managing the urban dynamics [1]. On the other hand, China’s urban policies are focused on integrated urban and rural development, the creation of city clusters to spread the benefits of urbanization, and the promotion of sustainable urban development. Though China’s urbanization is more policy-induced, India’s urbanization is more market-determined. Therefore, appropriate urban policies in India are required for proper design and implementation.
No country has ever reached middle-income status without a significant increase in urbanization [2]. Urbanization has contributed not only to higher income but also it has improved people’s lives [3, 4]. Therefore, the promotion of urbanization is very important for many developing countries such as India. Currently, India is facing numerous challenges as a result of enormous urban dwellers. India has now two challenges; first, it has to speed up the urbanization rate, and secondly, it has to make proper or planned urbanization so that the maximum benefits of urbanization are achievable. Urbanization use resources such as excess labor and land more productively and becomes the engine of economic growth.
To achieve planned urbanization for higher and sustainable economic growth Government of India (GoI) has taken Smart Cities Mission initiatives. In June 2015, the Ministry of Urban Development (MoUD) released a mission statement and guidelines for the Smart Cities Mission. This program replaced the previous major central government’s flagship program Jawaharlal Nehru National Urban Renewal Mission (JNNURM) and wanted to move India’s cities forward under Prime Minister Narendra Modi’s leadership. Under the guidelines, several strategies are sketched by which an applicant entity can apply to achieve smart city designation [5].
Though there is no universally accepted definition of ‘smart city’, India’s smart city development mission is meant to invest more on the core infrastructure elements such as water, electricity, sanitation, solid waste management, public transport, e-governance, etc. GoI also has proposed eight features of comprehensive development for smart cities. This includes promotion of mixed land use, housing and inclusiveness, creation of walkable localities, preservation and development of open spaces, promotion a variety of transport options, making governance citizen-friendly and cost effective, giving an identity to the city, applying Smart Solutions to infrastructure and services in area-based development to make them better.
In this context, the present chapter assesses the impact of higher infrastructure availability on the population size of the smart cities in India. For the analysis, we consider only 85 smart cities in India that have populations more than 1 lakh (class I cities). The relevance for consideration of these cities that the class I cities accommodate about 70.2% of the total urban population in 2011. This indicates that India’s urbanization is concentrated in and around the class I cities. Therefore, it is important to investigate whether a further increase in the infrastructure of class I cities escalate population or not. It is very important to increase urbanization in India as it is having a slower rate of urbanization.
There are very few following studies which explore the impact, structure, and implementation strategies of smart cities program in India. Russell et al. [6] argued that the Smart Cities Mission marks a continued shift for urban development policy in India away from direct government intervention. They argued that the cities nominated for the Smart Cities Mission have adequate levels of public services, a lower percentage of slums, and are bigger. Therefore, providing basic infrastructure to these cities is against the smart city ideas and concepts.
Praharaj et al. [7] indicated that Indian cities need synergy across urban policies for better results. They also stated that smart city plans lack integration and have a conflict with statutory master plans. Praharaj et al. [8] explored the relationship between active civic engagement and the availability of basic digital infrastructure and socio-economic standards in Indian cities. They provide important lessons for building future smart and connected cities as well as promoting healthy urban relationships and welfare, in the emerging economies of the world. Aijaz and Hoelscher [9] argued that to make the ‘smart city mission’ more equitable and sustainable the fair engagement of citizens and all stakeholders need to involve. Praharaj and Han [10] stated that the Indian smarty city discourse predominantly corporate-driven and technology-focused. Therefore, smart cities should engage with sustainability and community issues. Randhawa and Kumar [11] argued that smart city development policies lack concerns towards the natural environment which is an important dimension of sustainable development of a city.
Rana et al. [1] found that that ‘Governance’ is the most significant category of barriers for smart city development followed by ‘Economic; ‘Technology’; ‘Social’; ‘Environmental’ and ‘Legal and Ethical’ in India. Hoelscher [12] stated that the smart cities agenda in India appears to be characterized by a failure to conceptualize and develop an integrated set of policies, and while a clearer (yet contested) concept is emerging, the prospects for success are uncertain. Praharaj and Han [13] found that the vast disparities remain across India’s urban centers, located in different geographical regions, in terms of access to social capital and physical infrastructure. Their analysis suggests that education, health, and social services are important drivers in the urban typology building process. The small to medium sized cities in India are missing basic community infrastructure. This implies that smart city development strategy which considers one-size-fits-all by assuming importance of foundational infrastructure has the shortcomings. Tripathi [14] argued that smart cities in India should ensure smart distribution of benefits of urban economic growth to the poorer section of urban dwellers for future development of urban India.
Adapa [15] presents a comprehensive review of the existing smart city frameworks and cleaner production initiatives in the Indian context. Aijaz [16] argued that the negative effect of India’s urbanization includes informal-growth of peri-urban areas, escalating water crises, social exclusions, an extension of slums, and mismanagement of solid waste. The author argued that the success of smart city development only possible if civic institutions correctly understand the city’s social, economic, and physical requirements and its diversity. At the same time, citizens should show a greater sense of civic responsibility.
The brief review of the literature mainly suggests that how smart city development initiatives can be more effective if properly implemented. In other words, what are the important dimensions of India’s urbanization that have to be considered for the successful implementation of smart city development strategies which will lead to successful urban development in India? However, these studies have missed important dimensions of India’s urban development policy which is how to increase the urbanization rate which is essential for economic development. Therefore, the present study attempts to fulfill this gape for better urban development in the future.
To estimate the impact of infrastructure on smart cities we consider the following econometric model:
where
In the context of the positive impact of infrastructure on urbanization, Tiebout [19] indicated that accessibility and superiority of public facilities such as parking facilities, police protection, roads, parks, and municipal golf courses are very important for choosing a municipality. Therefore, consumer voters would migrate to a city that satisfied their demand for infrastructure. Harris and Todaro’s [20] model explained that rural to urban migration depends on expected rural–urban income differential rather than rural–urban wages. This indicates that urban condition is better with higher infrastructure facilities which attract more rural people [18].
In the context of India, several studies (e.g., [21, 22, 23, 24]) argued that India’s urban areas lack adequate infrastructure which requires urgent attention. Pradhan [25] investigated the impact of infrastructure on urbanization in India, using a composite infrastructure development index based on three sub-indexes: physical infrastructure, social infrastructure, and financial infrastructure. Using multivariate principal component analysis, the study confirmed that infrastructure has a significant positive impact on urbanization in India. On the contrast, Tripathi [18] argued that the improvement of infrastructure in large cities may not increase population concentration, but it will improve the living conditions and business activities that increase economic growth potential. Based on these studies we expect a positive or negative effect of infrastructure on urbanization driven by smart city development.
Details about the variable measurement and data sources are provided in Appendix A. Table 1 presents the summary statistics of each variable used in the analysis. The coefficient of variation (CV) measures the dispersions of data points in a data series. Log of the city population, city population density, and city-wise total number of colleges have lower values of a coefficient of variation (CV) which indicates that there are little differences in their means, implying a more symmetrical distribution. However, it is not the case for the city-wise total number of credit societies, city-wise total water supply capacity, the city-wise total number of banks, and the city-wise total number of latrines.
Variable | Mean | Standard deviation | Minimum | Maximum | Coefficient of variation |
---|---|---|---|---|---|
Log of city population (v1) | 13.52 | 0.91 | 11.59 | 15.96 | 6.75 |
City population growth rate (v2) | 19.02 | 22.54 | −60.00 | 111.00 | 118.46 |
City population density (v3) | 9084.07 | 5974.53 | 679 | 32622.00 | 65.77 |
City-wise total road length (v4) | 1160.34 | 1536.60 | 9.00 | 11812.00 | 132.43 |
City-wise total number of latrines (v5) | 198560.00 | 300578.80 | 1114 | 2063946.00 | 151.38 |
City wise total water supply capacity (kilo liter) (v6) | 115657.90 | 231942.40 | 0.00 | 1200000.00 | 200.54 |
City wise total number of electricity connection (v7) | 330136.00 | 449066.80 | 25500.00 | 2700000.00 | 136.02 |
City-wise total number of hospital (v8) | 198.67 | 310.98 | 5.00 | 1706.00 | 156.53 |
City-wise total number of schools (v9) | 859.68 | 1174.64 | 9.00 | 8397.00 | 136.64 |
City-wise total number of colleges (v10) | 67.98 | 75.29 | 1.00 | 532.00 | 110.76 |
City-wise total number of universities (v11) | 2.18 | 3.10 | 0.00 | 18.00 | 142.35 |
City-wise total number of banks (v12) | 185.51 | 366.68 | 2.00 | 2247.00 | 197.66 |
City-wise total number of credit societies (v13) | 272.95 | 806.75 | 0.00 | 5193.00 | 295.56 |
Description of data used for the analysis.
Note: calculations are based on 85 observations.
Table 2 shows the raw correlation of the variables. The results show that the log of the city population is positively associated with all the infrastructure variables. Most importantly, the log of city population highly correlated with city-wise road length, the city-wise total number of latrines, city-wise total number of electricity connection, and city wise total number of schools. On the other hand, the correlation between city population densities and infrastructure variables is not strong. Similar results are obtained for the correlation between city population growth rate and infrastructure variables.
V1 | V2 | V3 | V4 | V5 | V6 | V7 | V8 | V9 | V10 | V11 | V12 | V13 | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
V1 | 1.00 | ||||||||||||
V2 | 0.13 | 1.00 | |||||||||||
V3 | 0.23 | −0.11 | 1.00 | ||||||||||
V4 | 0.68 | −0.09 | 0.16 | 1.00 | |||||||||
V5 | 0.70 | 0.04 | 0.22 | 0.80 | 1.00 | ||||||||
V6 | 0.42 | 0.04 | −0.04 | 0.44 | 0.51 | 1.00 | |||||||
V7 | 0.75 | 0.05 | 0.27 | 0.81 | 0.91 | 0.41 | 1.00 | ||||||
V8 | 0.38 | −0.12 | 0.08 | 0.35 | 0.24 | 0.37 | 0.30 | 1.00 | |||||
V9 | 0.68 | −0.04 | 0.17 | 0.87 | 0.81 | 0.43 | 0.82 | 0.25 | 1.00 | ||||
V10 | 0.64 | 0.01 | −0.05 | 0.78 | 0.67 | 0.53 | 0.63 | 0.34 | 0.82 | 1.00 | |||
V11 | 0.56 | 0.04 | 0.10 | 0.55 | 0.69 | 0.35 | 0.68 | 0.37 | 0.68 | 0.56 | 1.00 | ||
V12 | 0.59 | −0.04 | 0.27 | 0.69 | 0.79 | 0.32 | 0.81 | 0.13 | 0.71 | 0.53 | 0.52 | 1.00 | |
V13 | 0.32 | 0.04 | 0.05 | 0.23 | 0.20 | −0.02 | 0.23 | 0.04 | 0.25 | 0.31 | 0.18 | 0.25 | 1.00 |
Correlation coefficient of the variables used for the analysis.
Note: see Table 1 for variable definitions. The calculation is based on 85 observations.
We now investigate the impact of infrastructure on the urbanization. Based on Tripathi [17, 18], we consider the city population, density, and growth rate for the measurement of urbanization. We consider a total of 10 variables to measure the infrastructure and stand as interdependent variables. Table 1 shows that there are considerable variations between the minimum and maximum values of the variables. The correlation coefficients show that data are more correlated as the values increase. Hence, factor analysis is considered to reduce the number of independent variables to obtain appropriate estimation.
To ensure the validity of data, Kaiser-Meyer-Olkin (KMO) and Bartlett’s Test of Sphericity are used. The KMO test is performed by using STATA version 14.1. The estimated results in Table 3 show that factor analysis is highly recommended as the KMO value is 0.851. The probability of Bartlett’s test of Sphericity is very significant (0.000 < 0.01). Thus, factor analysis is desirable.
KMO measure of sampling adequacy | 0.851 | |
Bartlett’s test of sphericity | Approximate chi-square | 707.040 |
Df | 45 | |
Sig. | 0.000 |
KMO and Bartlett’s test.
KMO, Kaiser-Meyer-Olkin. Source: Author’s calculation.
The initial eigenvalues (i.e., a variance of the factor) are presented in Table 4. The most variance is presented by the first factor, the next maximum amount of variance is considered by the second factor, and so on. The negative eigenvalues indicate that the matrix is not full rank suggesting six factors for the analysis can be considered at most. On the other hand, the KMO criterion recommends that factors with Eigenvalues ≥1 should be considered for the analyses. Therefore, the only first factor is relevant for the study that accounts for about 86% of the variance in the solution.
Factor | Eigenvalue | Difference | Proportion | Cumulative |
---|---|---|---|---|
Factor1 | 5.61362 | 5.01985 | 0.8569 | 0.8569 |
Factor2 | 0.59377 | 0.23801 | 0.0906 | 0.9475 |
Factor3 | 0.35576 | 0.14509 | 0.0543 | 1.0019 |
Factor4 | 0.21067 | 0.11021 | 0.0322 | 1.034 |
Factor5 | 0.10046 | 0.03567 | 0.0153 | 1.0493 |
Factor6 | 0.0648 | 0.09602 | 0.0099 | 1.0592 |
Factor7 | −0.03122 | 0.03265 | −0.0048 | 1.0545 |
Factor8 | −0.06387 | 0.06123 | −0.0097 | 1.0447 |
Factor9 | −0.1251 | 0.04279 | −0.0191 | 1.0256 |
Factor10 | −0.16789 | . | −0.0256 | 1 |
Explanation of total variance.
Source: Author’s calculation.
The factor loadings (pattern matrix) according to the uniqueness i.e., a variance is exclusive to the variable and not contributed by other variables is presented in Table 5. The bigger values of uniqueness indicate that variables are not properly explained by the factors. For instance, 93.3% of the variance in ‘total credit society’ is not contributed by the other variables in the overall factor model. On the contrary, the ‘total number of latrines’ that has very low variance (14.6%) is not shared by other variables. As the values of factor loading for approximately all variables are higher (>0.3), we can conclude that factor 1 is defined by all six variables that are considered to produce an infrastructure index. Quite importantly, factor1 is mostly related to the city-wise number of electricity connections and city-wise number of latrines. It is also important to note that as we are using one factor only, factor rotation which helps to see the underlying dimensions (scales) more clearly is not suitable as there’s nothing to rotate.
Variable | Factor1 | Uniqueness |
---|---|---|
Total road length | 0.8937 | 0.2013 |
Total number of latrines | 0.9241 | 0.146 |
Total water supply | 0.5232 | 0.7263 |
Total number of electricity connections | 0.9179 | 0.1575 |
Total number of schools | 0.923 | 0.1481 |
Total number of hospital | 0.3619 | 0.869 |
Total number of colleges | 0.8166 | 0.3332 |
Total number of universities | 0.721 | 0.4802 |
Total number of banks | 0.7801 | 0.3914 |
Total number of credit societies | 0.2583 | 0.9333 |
Factor loadings (pattern matrix) and unique variances for one factor model.
Source: Author’s calculation.
The linear regression analysis is used to investigate the impact of infrastructure on urbanization in India. Table 6 presents the results of the regression analysis. The factor score values for the one selected factor is considered as the independent variable. Regression models 1–5 present the estimated results for three dependents variables i.e., size, growth, and density of city populations. To control the heteroscedasticity problem we estimate the robust standard errors.
Dependent variable | |||||
---|---|---|---|---|---|
Log of city population 2011 | Log of city population 2020 | Log of city population 2025 | Log of city population density 2011 | Log of city population growth rate 2011 | |
Infrastructure index | 0.711*** (0.165) | 0.628*** (0.147) | 0.632*** (0.145) | 0.123* (0.074) | 0.218 (0.183) |
Constant | 13.516*** (0.064) | 7.142*** (0.079) | 7.256*** (0.079) | 8.961*** (0.065) | 2.987*** (0.096) |
F Statistics | 18.44*** | 18.33*** | 18.95*** | 2.80* | 1.42 |
R2 | 0.5886 | 0.4656 | 0.4648 | 0.0415 | 0.0343 |
Observations | 85 | 77 | 77 | 83 | 67 |
Results of regression analysis.
p < 0.1.
p < 0.01.
Robust standard errors in parentheses. Source: Estimated using Eq. (1).
Regression 1 shows that the infrastructure index has a positive and statistically significant effect on the smart city population in 2011. A 10% increase in infrastructure index increases the smart city population by 7.1%. This indicates that higher infrastructure investment increases the population of smart cities. On the other hand, a higher level of infrastructure also increases the population density of the smart cities in regression 4. The coefficient 0.123 indicates that a 10% increase in infrastructure index increases smart city density by 1.2%. However, infrastructure may not increase the growth rate of the city population as it has a statistically insignificant effect on it in regression 5. This is quite evident as most of the large cities considered for smart city development experienced a negative growth rate. For example, Thiruvananthapuram experienced a 14% negative population growth rate from the period of 2001 to 2011. Therefore, smart city development does not increase the population growth rate of smart cities.
To estimate the robustness of the results we consider smart city population data for 2020 and 2025 from World Urbanization Prospects (WUP): The 2018 Revision [26]. The WUP provides a data population of urban agglomerations with 300,000 inhabitants or more in 2018. On the other hand, though 11% of the total proposed work under the smart city mission completed in 2019, still we have to wait for 2021 (i.e., next Census data) for the evaluation of the impact of infrastructure on the population of smart cities. As some of the smart cities that are considered for our survey have a population less than 3 lakh we could collect data only 77 smart cities. The regression results 2 and 3 show that available infrastructure in 2011 has a positive and statistically significant effect on the log of the smart city population in 2020 and 2025. This indicates that infrastructure has a big role in the promotion of urbanization in India and smart city mission is very important for that.
The present chapter assesses the impact of infrastructure on the urbanization by smart cities in India. Smart city urbanization is measured by population, density, and growth rate of the population of the 85 smart cities in India. On the other hand, smart city-wise availability of infrastructure is measured by the considering city level total road length, number of latrines, water supply capacities, number of electricity connections, hospitals, schools, colleges, universities, banks, and credit societies.
The factor analysis is used to create an infrastructure index by considering all the infrastructure variables. The OLS regression analysis is used to measure the impact of infrastructure on urbanization. The OLS regression results suggest that the availability of infrastructure has a positive and statistically significant effect on the urbanization measured by the smart city population and densities of the smart city population. This indicates that the smart city mission promotes India’s urbanization.
India’s cities and towns are having a serious lack of adequate infrastructure facilities. The Report on Indian Urban Infrastructure and Services [21] urged that urban India severely faces deficiency in the provision of urban public services such as street lights, solid waste management, roads, sewerage, and drinking water. The report estimated that Rs 39.2 lakh crores at 2009–10 prices are required over a 20-year period to achieve this growth. The outlay on urban roads accounts for Rs 17.3 lakh crore (or 44%) of this amount. In this perspective, the smart cities mission is appropriate for the promotion of urbanization in India by huge investment in infrastructure. It is very much important to indicate that India had a total of 7935 cities and towns in 2011. Therefore, smart cities initiatives only for 100 cities may not fulfill the urbanization dream for India. In the coming years, India should have more smart cities to explore the benefits of urbanization for higher economic growth.
The Internet has irrevocably changed the dynamics of scholarly communication and publishing. Consequently, we find it necessary to indicate, unambiguously, our definition of what we consider to be a published scientific work.
",metaTitle:"Prior Publication Policy",metaDescription:"Prior Publication Policy",metaKeywords:null,canonicalURL:"/page/prior-publication-policy",contentRaw:'[{"type":"htmlEditorComponent","content":"A significant number of working papers, early drafts, and similar work in progress are openly shared online between members of the scientific community. It has become common to announce one’s own research on a personal website or a blog to gather comments and suggestions from other researchers. Such works and online postings are, indeed, published in the sense that they are made publicly available. However, this does not mean that if submitted for publication by IntechOpen they are not original works. We differentiate between reviewed and non-reviewed works when determining whether a work is original and has been published in a scholarly sense or not.
\\n\\nThe significance of Peer Review cannot be overstated when it comes to defining, in our terms, what constitutes a published scientific work. Peer Review is widely considered to be the cornerstone of modern publishing processes and the key value-adding contribution to a scholarly manuscript that a publisher can make.
\\n\\nOther than the issue of originality, research misconduct is another major issue that all publishers have to address. IntechOpen’s Retraction & Correction Policy and various publication ethics guidelines identify both redundant publication and (self)plagiarism to fall within the definition of research misconduct, thus constituting grounds for rejection or the issue of a Retraction if the work has already been published.
\\n\\nIn order to facilitate the tracking of a manuscript’s publishing history and its development from its earliest draft to the manuscript submitted, we encourage Authors to disclose any instances of a manuscript’s prior publication, whether it be through a conference presentation, a newspaper article, a working paper publicly available in a repository or a blog post.
\\n\\nA note to the Academic Editor containing detailed information about a submitted manuscript’s previous public availability is the preferred means of reporting prior publication. This helps us determine if there are any earlier versions of a manuscript that should be disclosed to our readers or if any of those earlier versions should be cited and listed in a manuscript’s references.
\\n\\nSome basic information about the editorial treatment of different varieties of prior publication is laid out below:
\\n\\n1. CONFERENCE PAPERS & PRESENTATIONS
\\n\\nGiven that conference papers and presentations generally pass through some sort of peer or editorial review, we consider them to be published in the accepted scholarly sense, particularly if they are published as a part of conference proceedings.
\\n\\nAll submitted manuscripts originating from a previously published conference paper must contain at least 50% of new original content to be accepted for review and considered for publication.
\\n\\nAuthors are required to report any links their manuscript might have with their earlier conference papers and presentations in a note to the Academic Editor, as well as in the manuscript itself. Additionally, Authors should obtain any necessary permissions from the publisher of their conference paper if copyright transfer occurred during the publishing process. Failure to do so may prevent Us from publishing an otherwise worthy work.
\\n\\n2. NEWSPAPER & MAGAZINE ARTICLES
\\n\\nNewspaper and magazine articles usually do not pass through any extensive peer or editorial review and we do not consider them to be published in the scholarly sense. Articles appearing in newspapers and magazines rarely possess the depth and structure characteristic of scholarly articles.
\\n\\nSubmitted manuscripts stemming from a previous newspaper or magazine article will be accepted for review and considered for publication. However, Authors are strongly advised to report any such publication in an accompanying note to the External Editor.
\\n\\nAs with the conference papers and presentations, Authors should obtain any necessary permissions from the newspaper or magazine that published the work, and indicate that they have done so in a note to the External Editor.
\\n\\n3. GREY LITERATURE
\\n\\nWhite papers, working papers, technical reports and all other forms of papers which fall within the scope of the ‘Luxembourg definition’ of grey literature do not pass through any extensive peer or editorial review and we do not consider them to be published in the scholarly sense.
\\n\\nAlthough such papers are regularly made publicly available via personal websites and institutional repositories, their general purpose is to gather comments and feedback from Authors’ colleagues in order to further improve a manuscript intended for future publication.
\\n\\nWhen submitting their work, Authors are required to disclose the existence of any publicly available earlier drafts in a note to the Academic Editor. In cases where earlier drafts of the submitted version of the manuscript are publicly available, any overlap between the versions will generally not be considered an instance of self-plagiarism.
\\n\\n4. SOCIAL MEDIA, BLOG & MESSAGE BOARD POSTINGS
\\n\\nWe feel that social media, blogs and message boards are generally used with the same intention as grey literature, to formulate ideas for a manuscript and gather early feedback from like-minded researchers in order to improve a particular piece of work before submitting it for publication. Therefore, we do not consider such internet postings to be publication in the scholarly sense.
\\n\\nNevertheless, Authors are encouraged to disclose the existence of any internet postings in which they outline and describe their research or posted passages of their manuscripts in a note to the Academic Editor. Please note that we will not strictly enforce this request in the same way that we would instructions we consider to be part of our conditions of acceptance for publication. We understand that it may be difficult to keep track of all one’s internet postings in which the researcher´s current work might be mentioned.
\\n\\nIn cases where there is any overlap between the Author´s submitted manuscript and related internet postings, we will generally not consider it to be an instance of self-plagiarism. This also holds true for any co-Author as well.
\\n\\nFor more information on this policy please contact permissions@intechopen.com.
\\n\\nPolicy last updated: 2017-03-20
\\n"}]'},components:[{type:"htmlEditorComponent",content:'A significant number of working papers, early drafts, and similar work in progress are openly shared online between members of the scientific community. It has become common to announce one’s own research on a personal website or a blog to gather comments and suggestions from other researchers. Such works and online postings are, indeed, published in the sense that they are made publicly available. However, this does not mean that if submitted for publication by IntechOpen they are not original works. We differentiate between reviewed and non-reviewed works when determining whether a work is original and has been published in a scholarly sense or not.
\n\nThe significance of Peer Review cannot be overstated when it comes to defining, in our terms, what constitutes a published scientific work. Peer Review is widely considered to be the cornerstone of modern publishing processes and the key value-adding contribution to a scholarly manuscript that a publisher can make.
\n\nOther than the issue of originality, research misconduct is another major issue that all publishers have to address. IntechOpen’s Retraction & Correction Policy and various publication ethics guidelines identify both redundant publication and (self)plagiarism to fall within the definition of research misconduct, thus constituting grounds for rejection or the issue of a Retraction if the work has already been published.
\n\nIn order to facilitate the tracking of a manuscript’s publishing history and its development from its earliest draft to the manuscript submitted, we encourage Authors to disclose any instances of a manuscript’s prior publication, whether it be through a conference presentation, a newspaper article, a working paper publicly available in a repository or a blog post.
\n\nA note to the Academic Editor containing detailed information about a submitted manuscript’s previous public availability is the preferred means of reporting prior publication. This helps us determine if there are any earlier versions of a manuscript that should be disclosed to our readers or if any of those earlier versions should be cited and listed in a manuscript’s references.
\n\nSome basic information about the editorial treatment of different varieties of prior publication is laid out below:
\n\n1. CONFERENCE PAPERS & PRESENTATIONS
\n\nGiven that conference papers and presentations generally pass through some sort of peer or editorial review, we consider them to be published in the accepted scholarly sense, particularly if they are published as a part of conference proceedings.
\n\nAll submitted manuscripts originating from a previously published conference paper must contain at least 50% of new original content to be accepted for review and considered for publication.
\n\nAuthors are required to report any links their manuscript might have with their earlier conference papers and presentations in a note to the Academic Editor, as well as in the manuscript itself. Additionally, Authors should obtain any necessary permissions from the publisher of their conference paper if copyright transfer occurred during the publishing process. Failure to do so may prevent Us from publishing an otherwise worthy work.
\n\n2. NEWSPAPER & MAGAZINE ARTICLES
\n\nNewspaper and magazine articles usually do not pass through any extensive peer or editorial review and we do not consider them to be published in the scholarly sense. Articles appearing in newspapers and magazines rarely possess the depth and structure characteristic of scholarly articles.
\n\nSubmitted manuscripts stemming from a previous newspaper or magazine article will be accepted for review and considered for publication. However, Authors are strongly advised to report any such publication in an accompanying note to the External Editor.
\n\nAs with the conference papers and presentations, Authors should obtain any necessary permissions from the newspaper or magazine that published the work, and indicate that they have done so in a note to the External Editor.
\n\n3. GREY LITERATURE
\n\nWhite papers, working papers, technical reports and all other forms of papers which fall within the scope of the ‘Luxembourg definition’ of grey literature do not pass through any extensive peer or editorial review and we do not consider them to be published in the scholarly sense.
\n\nAlthough such papers are regularly made publicly available via personal websites and institutional repositories, their general purpose is to gather comments and feedback from Authors’ colleagues in order to further improve a manuscript intended for future publication.
\n\nWhen submitting their work, Authors are required to disclose the existence of any publicly available earlier drafts in a note to the Academic Editor. In cases where earlier drafts of the submitted version of the manuscript are publicly available, any overlap between the versions will generally not be considered an instance of self-plagiarism.
\n\n4. SOCIAL MEDIA, BLOG & MESSAGE BOARD POSTINGS
\n\nWe feel that social media, blogs and message boards are generally used with the same intention as grey literature, to formulate ideas for a manuscript and gather early feedback from like-minded researchers in order to improve a particular piece of work before submitting it for publication. Therefore, we do not consider such internet postings to be publication in the scholarly sense.
\n\nNevertheless, Authors are encouraged to disclose the existence of any internet postings in which they outline and describe their research or posted passages of their manuscripts in a note to the Academic Editor. Please note that we will not strictly enforce this request in the same way that we would instructions we consider to be part of our conditions of acceptance for publication. We understand that it may be difficult to keep track of all one’s internet postings in which the researcher´s current work might be mentioned.
\n\nIn cases where there is any overlap between the Author´s submitted manuscript and related internet postings, we will generally not consider it to be an instance of self-plagiarism. This also holds true for any co-Author as well.
\n\nFor more information on this policy please contact permissions@intechopen.com.
\n\nPolicy last updated: 2017-03-20
\n'}]},successStories:{items:[]},authorsAndEditors:{filterParams:{},profiles:[{id:"396",title:"Dr.",name:"Vedran",middleName:null,surname:"Kordic",slug:"vedran-kordic",fullName:"Vedran Kordic",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/396/images/7281_n.png",biography:"After obtaining his Master's degree in Mechanical Engineering he continued his education at the Vienna University of Technology where he obtained his PhD degree in 2004. He worked as a researcher at the Automation and Control Institute, Faculty of Electrical Engineering, Vienna University of Technology until 2008. His studies in robotics lead him not only to a PhD degree but also inspired him to co-found and build the International Journal of Advanced Robotic Systems - world's first Open Access journal in the field of robotics.",institutionString:null,institution:{name:"TU Wien",country:{name:"Austria"}}},{id:"441",title:"Ph.D.",name:"Jaekyu",middleName:null,surname:"Park",slug:"jaekyu-park",fullName:"Jaekyu Park",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/441/images/1881_n.jpg",biography:null,institutionString:null,institution:{name:"LG Corporation (South Korea)",country:{name:"Korea, South"}}},{id:"465",title:"Dr",name:"Christian",middleName:null,surname:"Martens",slug:"christian-martens",fullName:"Christian Martens",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"479",title:"Dr.",name:"Valentina",middleName:null,surname:"Colla",slug:"valentina-colla",fullName:"Valentina Colla",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/479/images/358_n.jpg",biography:null,institutionString:null,institution:{name:"Sant'Anna School of Advanced Studies",country:{name:"Italy"}}},{id:"494",title:"PhD",name:"Loris",middleName:null,surname:"Nanni",slug:"loris-nanni",fullName:"Loris Nanni",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/494/images/system/494.jpg",biography:"Loris Nanni received his Master Degree cum laude on June-2002 from the University of Bologna, and the April 26th 2006 he received his Ph.D. in Computer Engineering at DEIS, University of Bologna. On September, 29th 2006 he has won a post PhD fellowship from the university of Bologna (from October 2006 to October 2008), at the competitive examination he was ranked first in the industrial engineering area. He extensively served as referee for several international journals. He is author/coauthor of more than 100 research papers. He has been involved in some projects supported by MURST and European Community. His research interests include pattern recognition, bioinformatics, and biometric systems (fingerprint classification and recognition, signature verification, face recognition).",institutionString:null,institution:null},{id:"496",title:"Dr.",name:"Carlos",middleName:null,surname:"Leon",slug:"carlos-leon",fullName:"Carlos Leon",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Seville",country:{name:"Spain"}}},{id:"512",title:"Dr.",name:"Dayang",middleName:null,surname:"Jawawi",slug:"dayang-jawawi",fullName:"Dayang Jawawi",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Technology Malaysia",country:{name:"Malaysia"}}},{id:"528",title:"Dr.",name:"Kresimir",middleName:null,surname:"Delac",slug:"kresimir-delac",fullName:"Kresimir Delac",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/528/images/system/528.jpg",biography:"K. Delac received his B.Sc.E.E. degree in 2003 and is currentlypursuing a Ph.D. degree at the University of Zagreb, Faculty of Electrical Engineering andComputing. His current research interests are digital image analysis, pattern recognition andbiometrics.",institutionString:null,institution:{name:"University of Zagreb",country:{name:"Croatia"}}},{id:"557",title:"Dr.",name:"Andon",middleName:"Venelinov",surname:"Topalov",slug:"andon-topalov",fullName:"Andon Topalov",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/557/images/1927_n.jpg",biography:"Dr. Andon V. Topalov received the MSc degree in Control Engineering from the Faculty of Information Systems, Technologies, and Automation at Moscow State University of Civil Engineering (MGGU) in 1979. He then received his PhD degree in Control Engineering from the Department of Automation and Remote Control at Moscow State Mining University (MGSU), Moscow, in 1984. From 1985 to 1986, he was a Research Fellow in the Research Institute for Electronic Equipment, ZZU AD, Plovdiv, Bulgaria. In 1986, he joined the Department of Control Systems, Technical University of Sofia at the Plovdiv campus, where he is presently a Full Professor. He has held long-term visiting Professor/Scholar positions at various institutions in South Korea, Turkey, Mexico, Greece, Belgium, UK, and Germany. And he has coauthored one book and authored or coauthored more than 80 research papers in conference proceedings and journals. His current research interests are in the fields of intelligent control and robotics.",institutionString:null,institution:{name:"Technical University of Sofia",country:{name:"Bulgaria"}}},{id:"585",title:"Prof.",name:"Munir",middleName:null,surname:"Merdan",slug:"munir-merdan",fullName:"Munir Merdan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/585/images/system/585.jpg",biography:"Munir Merdan received the M.Sc. degree in mechanical engineering from the Technical University of Sarajevo, Bosnia and Herzegovina, in 2001, and the Ph.D. degree in electrical engineering from the Vienna University of Technology, Vienna, Austria, in 2009.Since 2005, he has been at the Automation and Control Institute, Vienna University of Technology, where he is currently a Senior Researcher. His research interests include the application of agent technology for achieving agile control in the manufacturing environment.",institutionString:null,institution:null},{id:"605",title:"Prof",name:"Dil",middleName:null,surname:"Hussain",slug:"dil-hussain",fullName:"Dil Hussain",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/605/images/system/605.jpg",biography:"Dr. Dil Muhammad Akbar Hussain is a professor of Electronics Engineering & Computer Science at the Department of Energy Technology, Aalborg University Denmark. Professor Akbar has a Master degree in Digital Electronics from Govt. College University, Lahore Pakistan and a P-hD degree in Control Engineering from the School of Engineering and Applied Sciences, University of Sussex United Kingdom. Aalborg University has Two Satellite Campuses, one in Copenhagen (Aalborg University Copenhagen) and the other in Esbjerg (Aalborg University Esbjerg).\n· He is a member of prestigious IEEE (Institute of Electrical and Electronics Engineers), and IAENG (International Association of Engineers) organizations. \n· He is the chief Editor of the Journal of Software Engineering.\n· He is the member of the Editorial Board of International Journal of Computer Science and Software Technology (IJCSST) and International Journal of Computer Engineering and Information Technology. \n· He is also the Editor of Communication in Computer and Information Science CCIS-20 by Springer.\n· Reviewer For Many Conferences\nHe is the lead person in making collaboration agreements between Aalborg University and many universities of Pakistan, for which the MOU’s (Memorandum of Understanding) have been signed.\nProfessor Akbar is working in Academia since 1990, he started his career as a Lab demonstrator/TA at the University of Sussex. After finishing his P. hD degree in 1992, he served in the Industry as a Scientific Officer and continued his academic career as a visiting scholar for a number of educational institutions. In 1996 he joined National University of Science & Technology Pakistan (NUST) as an Associate Professor; NUST is one of the top few universities in Pakistan. In 1999 he joined an International Company Lineo Inc, Canada as Manager Compiler Group, where he headed the group for developing Compiler Tool Chain and Porting of Operating Systems for the BLACKfin processor. The processor development was a joint venture by Intel and Analog Devices. In 2002 Lineo Inc., was taken over by another company, so he joined Aalborg University Denmark as an Assistant Professor.\nProfessor Akbar has truly a multi-disciplined career and he continued his legacy and making progress in many areas of his interests both in teaching and research. He has contributed in stochastic estimation of control area especially, in the Multiple Target Tracking and Interactive Multiple Model (IMM) research, Ball & Beam Control Problem, Robotics, Levitation Control. He has contributed in developing Algorithms for Fingerprint Matching, Computer Vision and Face Recognition. He has been supervising Pattern Recognition, Formal Languages and Distributed Processing projects for several years. He has reviewed many books on Management, Computer Science. Currently, he is an active and permanent reviewer for many international conferences and symposia and the program committee member for many international conferences.\nIn teaching he has taught the core computer science subjects like, Digital Design, Real Time Embedded System Programming, Operating Systems, Software Engineering, Data Structures, Databases, Compiler Construction. In the Engineering side, Digital Signal Processing, Computer Architecture, Electronics Devices, Digital Filtering and Engineering Management.\nApart from his Academic Interest and activities he loves sport especially, Cricket, Football, Snooker and Squash. He plays cricket for Esbjerg city in the second division team as an opener wicket keeper batsman. He is a very good player of squash but has not played squash since his arrival in Denmark.",institutionString:null,institution:null},{id:"611",title:"Prof.",name:"T",middleName:null,surname:"Nagarajan",slug:"t-nagarajan",fullName:"T Nagarajan",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Universiti Teknologi Petronas",country:{name:"Malaysia"}}}],filtersByRegion:[{group:"region",caption:"North America",value:1,count:6654},{group:"region",caption:"Middle and South America",value:2,count:5945},{group:"region",caption:"Africa",value:3,count:2452},{group:"region",caption:"Asia",value:4,count:12681},{group:"region",caption:"Australia and Oceania",value:5,count:1014},{group:"region",caption:"Europe",value:6,count:17701}],offset:12,limit:12,total:133951},chapterEmbeded:{data:{}},editorApplication:{success:null,errors:{}},ofsBooks:{filterParams:{topicId:"12"},books:[{type:"book",id:"10845",title:"Marine Ecosystems - Biodiversity, Ecosystem Services and Human Impacts",subtitle:null,isOpenForSubmission:!0,hash:"727e7eb3d4ba529ec5eb4f150e078523",slug:null,bookSignature:"Dr. Ana M.M. Marta Gonçalves",coverURL:"https://cdn.intechopen.com/books/images_new/10845.jpg",editedByType:null,editors:[{id:"320124",title:"Dr.",name:"Ana M.M.",surname:"Gonçalves",slug:"ana-m.m.-goncalves",fullName:"Ana M.M. Gonçalves"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11450",title:"Environmental Impacts of COVID-19 Pandemic on the World",subtitle:null,isOpenForSubmission:!0,hash:"a58c7b02d07903004be70f744f2e1835",slug:null,bookSignature:"Prof. Mohamed Nageeb Rashed and Prof. Wafaa M. Abd El-Rahim",coverURL:"https://cdn.intechopen.com/books/images_new/11450.jpg",editedByType:null,editors:[{id:"63465",title:"Prof.",name:"Mohamed Nageeb",surname:"Rashed",slug:"mohamed-nageeb-rashed",fullName:"Mohamed Nageeb Rashed"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11457",title:"Forest Degradation Under Global Change",subtitle:null,isOpenForSubmission:!0,hash:"8df7150b01ae754024c65d1a62f190d9",slug:null,bookSignature:"Dr. Pavel Samec",coverURL:"https://cdn.intechopen.com/books/images_new/11457.jpg",editedByType:null,editors:[{id:"317087",title:"Dr.",name:"Pavel",surname:"Samec",slug:"pavel-samec",fullName:"Pavel Samec"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11650",title:"Aquifers - New Insights",subtitle:null,isOpenForSubmission:!0,hash:"27c1a2a053cb1d83de903c5b969bc3a2",slug:null,bookSignature:"Dr. Abhay Soni and Dr. Prabhat Jain",coverURL:"https://cdn.intechopen.com/books/images_new/11650.jpg",editedByType:null,editors:[{id:"271093",title:"Dr.",name:"Abhay",surname:"Soni",slug:"abhay-soni",fullName:"Abhay Soni"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11664",title:"Recent Advances in Sensing Technologies for Environmental Control and Monitoring",subtitle:null,isOpenForSubmission:!0,hash:"cf1ee76443e393bc7597723c3ee3e26f",slug:null,bookSignature:"Dr. Toonika Rinken and Dr. Kairi Kivirand",coverURL:"https://cdn.intechopen.com/books/images_new/11664.jpg",editedByType:null,editors:[{id:"24687",title:"Dr.",name:"Toonika",surname:"Rinken",slug:"toonika-rinken",fullName:"Toonika Rinken"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11665",title:"Recent Advances in Wildlife Management",subtitle:null,isOpenForSubmission:!0,hash:"73da0df494a1a56ab9c4faf2ee811899",slug:null,bookSignature:"Dr. Farzana Khan Perveen",coverURL:"https://cdn.intechopen.com/books/images_new/11665.jpg",editedByType:null,editors:[{id:"75563",title:"Dr.",name:"Farzana Khan",surname:"Perveen",slug:"farzana-khan-perveen",fullName:"Farzana Khan Perveen"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11666",title:"Soil Contamination - Recent Advances and Future Perspectives",subtitle:null,isOpenForSubmission:!0,hash:"c8890038b86fb6e5af16ea3c22669ae9",slug:null,bookSignature:"Dr. Adnan Mustafa and Dr. Muhammad Naveed",coverURL:"https://cdn.intechopen.com/books/images_new/11666.jpg",editedByType:null,editors:[{id:"299110",title:"Dr.",name:"Adnan",surname:"Mustafa",slug:"adnan-mustafa",fullName:"Adnan Mustafa"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11668",title:"Mercury Pollution",subtitle:null,isOpenForSubmission:!0,hash:"0bd111f57835089cad4a9741326dbab7",slug:null,bookSignature:"Dr. Ahmed Abdelhafez and Dr. Mohamed Abbas",coverURL:"https://cdn.intechopen.com/books/images_new/11668.jpg",editedByType:null,editors:[{id:"196849",title:"Dr.",name:"Ahmed",surname:"Abdelhafez",slug:"ahmed-abdelhafez",fullName:"Ahmed Abdelhafez"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"12130",title:"Sustainable Built Environment",subtitle:null,isOpenForSubmission:!0,hash:"ed1dbae71b967e06efb049208f0c1068",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/12130.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"12131",title:"Climate Change and Fires",subtitle:null,isOpenForSubmission:!0,hash:"ea0858f07a3e87aaf9e5eaa75b4b44bd",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/12131.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"12180",title:"Wetlands",subtitle:null,isOpenForSubmission:!0,hash:"8957c5c2baaed32223f911a6d4aa5a03",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/12180.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"12221",title:"Air Pollution",subtitle:null,isOpenForSubmission:!0,hash:"439a018ee0c4960560cb798601f2a372",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/12221.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],filtersByTopic:[{group:"topic",caption:"Agricultural and Biological Sciences",value:5,count:40},{group:"topic",caption:"Biochemistry, Genetics and Molecular Biology",value:6,count:13},{group:"topic",caption:"Business, Management and Economics",value:7,count:7},{group:"topic",caption:"Chemistry",value:8,count:23},{group:"topic",caption:"Computer and Information Science",value:9,count:24},{group:"topic",caption:"Earth and Planetary Sciences",value:10,count:17},{group:"topic",caption:"Engineering",value:11,count:66},{group:"topic",caption:"Environmental Sciences",value:12,count:10},{group:"topic",caption:"Immunology and Microbiology",value:13,count:16},{group:"topic",caption:"Materials Science",value:14,count:26},{group:"topic",caption:"Mathematics",value:15,count:11},{group:"topic",caption:"Medicine",value:16,count:124},{group:"topic",caption:"Nanotechnology and Nanomaterials",value:17,count:8},{group:"topic",caption:"Neuroscience",value:18,count:4},{group:"topic",caption:"Pharmacology, Toxicology and Pharmaceutical Science",value:19,count:9},{group:"topic",caption:"Physics",value:20,count:10},{group:"topic",caption:"Psychology",value:21,count:10},{group:"topic",caption:"Robotics",value:22,count:2},{group:"topic",caption:"Social Sciences",value:23,count:9},{group:"topic",caption:"Veterinary Medicine and Science",value:25,count:4}],offset:12,limit:12,total:15},popularBooks:{featuredBooks:[{type:"book",id:"10901",title:"Grapes and Wine",subtitle:null,isOpenForSubmission:!1,hash:"5d7f2aa74874444bc6986e613ccebd7c",slug:"grapes-and-wine",bookSignature:"Antonio Morata, Iris Loira and Carmen González",coverURL:"https://cdn.intechopen.com/books/images_new/10901.jpg",editors:[{id:"180952",title:"Prof.",name:"Antonio",middleName:null,surname:"Morata",slug:"antonio-morata",fullName:"Antonio Morata"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11012",title:"Radiopharmaceuticals",subtitle:"Current Research for Better Diagnosis and Therapy",isOpenForSubmission:!1,hash:"f9046d6f96148b285e776f384991120d",slug:"radiopharmaceuticals-current-research-for-better-diagnosis-and-therapy",bookSignature:"Farid A. Badria",coverURL:"https://cdn.intechopen.com/books/images_new/11012.jpg",editors:[{id:"41865",title:"Prof.",name:"Farid A.",middleName:null,surname:"Badria",slug:"farid-a.-badria",fullName:"Farid A. Badria"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10787",title:"Hepatocellular Carcinoma",subtitle:"Challenges and Opportunities of a Multidisciplinary Approach",isOpenForSubmission:!1,hash:"bc00a66513e51003e5dbbc0294e0fc3d",slug:"hepatocellular-carcinoma-challenges-and-opportunities-of-a-multidisciplinary-approach",bookSignature:"Georgios Tsoulfas",coverURL:"https://cdn.intechopen.com/books/images_new/10787.jpg",editors:[{id:"57412",title:"Prof.",name:"Georgios",middleName:null,surname:"Tsoulfas",slug:"georgios-tsoulfas",fullName:"Georgios Tsoulfas"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10841",title:"Hydrolases",subtitle:null,isOpenForSubmission:!1,hash:"4e868cde273d65a7ff54b1817d640629",slug:"hydrolases",bookSignature:"Sajjad Haider, Adnan Haider and Angel Catalá",coverURL:"https://cdn.intechopen.com/books/images_new/10841.jpg",editors:[{id:"110708",title:"Dr.",name:"Sajjad",middleName:null,surname:"Haider",slug:"sajjad-haider",fullName:"Sajjad Haider"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10797",title:"Cell Culture",subtitle:"Advanced Technology and Applications in Medical and Life Sciences",isOpenForSubmission:!1,hash:"2c628f4757f9639a4450728d839a7842",slug:"cell-culture-advanced-technology-and-applications-in-medical-and-life-sciences",bookSignature:"Xianquan Zhan",coverURL:"https://cdn.intechopen.com/books/images_new/10797.jpg",editors:[{id:"223233",title:"Prof.",name:"Xianquan",middleName:null,surname:"Zhan",slug:"xianquan-zhan",fullName:"Xianquan Zhan"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9537",title:"Human Rights in the Contemporary World",subtitle:null,isOpenForSubmission:!1,hash:"54f05b93812fd434f3962956d6413a6b",slug:"human-rights-in-the-contemporary-world",bookSignature:"Trudy Corrigan",coverURL:"https://cdn.intechopen.com/books/images_new/9537.jpg",editors:[{id:"197557",title:"Dr.",name:"Trudy",middleName:null,surname:"Corrigan",slug:"trudy-corrigan",fullName:"Trudy Corrigan"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10193",title:"Multidisciplinary Experiences in Renal Replacement Therapy",subtitle:null,isOpenForSubmission:!1,hash:"3c4738671bb3e815744d1e04df7ba879",slug:"multidisciplinary-experiences-in-renal-replacement-therapy",bookSignature:"Ane C.F. Nunes",coverURL:"https://cdn.intechopen.com/books/images_new/10193.jpg",editors:[{id:"55270",title:"Prof.",name:"Ane",middleName:null,surname:"Claudia Fernandes Nunes",slug:"ane-claudia-fernandes-nunes",fullName:"Ane Claudia Fernandes Nunes"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10983",title:"Conifers",subtitle:"Recent Advances",isOpenForSubmission:!1,hash:"3e524d29fc3f95c3389efbd41463dab6",slug:"conifers-recent-advances",bookSignature:"Ana Cristina Gonçalves and Teresa Fonseca",coverURL:"https://cdn.intechopen.com/books/images_new/10983.jpg",editors:[{id:"194484",title:"Prof.",name:"Ana Cristina",middleName:null,surname:"Gonçalves",slug:"ana-cristina-goncalves",fullName:"Ana Cristina Gonçalves"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10539",title:"Ginseng",subtitle:"Modern Aspects of the Famed Traditional Medicine",isOpenForSubmission:!1,hash:"5f388543a066b617d2c52bd4c027c272",slug:"ginseng-modern-aspects-of-the-famed-traditional-medicine",bookSignature:"Christophe Hano and Jen-Tsung Chen",coverURL:"https://cdn.intechopen.com/books/images_new/10539.jpg",editors:[{id:"313856",title:"Dr.",name:"Christophe",middleName:"F.E.",surname:"Hano",slug:"christophe-hano",fullName:"Christophe Hano"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10881",title:"Drug Repurposing",subtitle:"Molecular Aspects and Therapeutic Applications",isOpenForSubmission:!1,hash:"eca3f2d5ca97b457d38a2442b36d3ac7",slug:"drug-repurposing-molecular-aspects-and-therapeutic-applications",bookSignature:"Shailendra K. Saxena",coverURL:"https://cdn.intechopen.com/books/images_new/10881.jpg",editors:[{id:"158026",title:"Prof.",name:"Shailendra K.",middleName:null,surname:"Saxena",slug:"shailendra-k.-saxena",fullName:"Shailendra K. Saxena"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9974",title:"E-Learning and Digital Education in the Twenty-First Century",subtitle:null,isOpenForSubmission:!1,hash:"88b58d66e975df20425fc1dfd22d53aa",slug:"e-learning-and-digital-education-in-the-twenty-first-century",bookSignature:"M. Mahruf C. Shohel",coverURL:"https://cdn.intechopen.com/books/images_new/9974.jpg",editors:[{id:"94099",title:"Dr.",name:"M. Mahruf C.",middleName:null,surname:"Shohel",slug:"m.-mahruf-c.-shohel",fullName:"M. Mahruf C. Shohel"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10356",title:"Natural Medicinal Plants",subtitle:null,isOpenForSubmission:!1,hash:"943e56ccaaf19ff696d25aa638ae37d6",slug:"natural-medicinal-plants",bookSignature:"Hany A. El-Shemy",coverURL:"https://cdn.intechopen.com/books/images_new/10356.jpg",editors:[{id:"54719",title:"Prof.",name:"Hany",middleName:null,surname:"El-Shemy",slug:"hany-el-shemy",fullName:"Hany El-Shemy"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}}],offset:12,limit:12,total:4423},hotBookTopics:{hotBooks:[],offset:0,limit:12,total:null},publish:{},publishingProposal:{success:null,errors:{}},books:{featuredBooks:[{type:"book",id:"10901",title:"Grapes and Wine",subtitle:null,isOpenForSubmission:!1,hash:"5d7f2aa74874444bc6986e613ccebd7c",slug:"grapes-and-wine",bookSignature:"Antonio Morata, Iris Loira and Carmen González",coverURL:"https://cdn.intechopen.com/books/images_new/10901.jpg",publishedDate:"June 15th 2022",numberOfDownloads:2204,editors:[{id:"180952",title:"Prof.",name:"Antonio",middleName:null,surname:"Morata",slug:"antonio-morata",fullName:"Antonio Morata"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11012",title:"Radiopharmaceuticals",subtitle:"Current Research for Better Diagnosis and Therapy",isOpenForSubmission:!1,hash:"f9046d6f96148b285e776f384991120d",slug:"radiopharmaceuticals-current-research-for-better-diagnosis-and-therapy",bookSignature:"Farid A. Badria",coverURL:"https://cdn.intechopen.com/books/images_new/11012.jpg",publishedDate:"June 15th 2022",numberOfDownloads:1182,editors:[{id:"41865",title:"Prof.",name:"Farid A.",middleName:null,surname:"Badria",slug:"farid-a.-badria",fullName:"Farid A. Badria"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10787",title:"Hepatocellular Carcinoma",subtitle:"Challenges and Opportunities of a Multidisciplinary Approach",isOpenForSubmission:!1,hash:"bc00a66513e51003e5dbbc0294e0fc3d",slug:"hepatocellular-carcinoma-challenges-and-opportunities-of-a-multidisciplinary-approach",bookSignature:"Georgios Tsoulfas",coverURL:"https://cdn.intechopen.com/books/images_new/10787.jpg",publishedDate:"June 15th 2022",numberOfDownloads:1006,editors:[{id:"57412",title:"Prof.",name:"Georgios",middleName:null,surname:"Tsoulfas",slug:"georgios-tsoulfas",fullName:"Georgios Tsoulfas"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10841",title:"Hydrolases",subtitle:null,isOpenForSubmission:!1,hash:"4e868cde273d65a7ff54b1817d640629",slug:"hydrolases",bookSignature:"Sajjad Haider, Adnan Haider and Angel Catalá",coverURL:"https://cdn.intechopen.com/books/images_new/10841.jpg",publishedDate:"June 15th 2022",numberOfDownloads:863,editors:[{id:"110708",title:"Dr.",name:"Sajjad",middleName:null,surname:"Haider",slug:"sajjad-haider",fullName:"Sajjad Haider"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10797",title:"Cell Culture",subtitle:"Advanced Technology and Applications in Medical and Life Sciences",isOpenForSubmission:!1,hash:"2c628f4757f9639a4450728d839a7842",slug:"cell-culture-advanced-technology-and-applications-in-medical-and-life-sciences",bookSignature:"Xianquan Zhan",coverURL:"https://cdn.intechopen.com/books/images_new/10797.jpg",publishedDate:"June 15th 2022",numberOfDownloads:793,editors:[{id:"223233",title:"Prof.",name:"Xianquan",middleName:null,surname:"Zhan",slug:"xianquan-zhan",fullName:"Xianquan Zhan"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10193",title:"Multidisciplinary Experiences in Renal Replacement Therapy",subtitle:null,isOpenForSubmission:!1,hash:"3c4738671bb3e815744d1e04df7ba879",slug:"multidisciplinary-experiences-in-renal-replacement-therapy",bookSignature:"Ane C.F. Nunes",coverURL:"https://cdn.intechopen.com/books/images_new/10193.jpg",publishedDate:"June 15th 2022",numberOfDownloads:730,editors:[{id:"55270",title:"Prof.",name:"Ane",middleName:null,surname:"Claudia Fernandes Nunes",slug:"ane-claudia-fernandes-nunes",fullName:"Ane Claudia Fernandes Nunes"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9537",title:"Human Rights in the Contemporary World",subtitle:null,isOpenForSubmission:!1,hash:"54f05b93812fd434f3962956d6413a6b",slug:"human-rights-in-the-contemporary-world",bookSignature:"Trudy Corrigan",coverURL:"https://cdn.intechopen.com/books/images_new/9537.jpg",publishedDate:"June 8th 2022",numberOfDownloads:2167,editors:[{id:"197557",title:"Dr.",name:"Trudy",middleName:null,surname:"Corrigan",slug:"trudy-corrigan",fullName:"Trudy Corrigan"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10983",title:"Conifers",subtitle:"Recent Advances",isOpenForSubmission:!1,hash:"3e524d29fc3f95c3389efbd41463dab6",slug:"conifers-recent-advances",bookSignature:"Ana Cristina Gonçalves and Teresa Fonseca",coverURL:"https://cdn.intechopen.com/books/images_new/10983.jpg",publishedDate:"June 15th 2022",numberOfDownloads:600,editors:[{id:"194484",title:"Prof.",name:"Ana Cristina",middleName:null,surname:"Gonçalves",slug:"ana-cristina-goncalves",fullName:"Ana Cristina Gonçalves"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10539",title:"Ginseng",subtitle:"Modern Aspects of the Famed Traditional Medicine",isOpenForSubmission:!1,hash:"5f388543a066b617d2c52bd4c027c272",slug:"ginseng-modern-aspects-of-the-famed-traditional-medicine",bookSignature:"Christophe Hano and Jen-Tsung Chen",coverURL:"https://cdn.intechopen.com/books/images_new/10539.jpg",publishedDate:"June 15th 2022",numberOfDownloads:583,editors:[{id:"313856",title:"Dr.",name:"Christophe",middleName:"F.E.",surname:"Hano",slug:"christophe-hano",fullName:"Christophe Hano"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10881",title:"Drug Repurposing",subtitle:"Molecular Aspects and Therapeutic Applications",isOpenForSubmission:!1,hash:"eca3f2d5ca97b457d38a2442b36d3ac7",slug:"drug-repurposing-molecular-aspects-and-therapeutic-applications",bookSignature:"Shailendra K. Saxena",coverURL:"https://cdn.intechopen.com/books/images_new/10881.jpg",publishedDate:"June 1st 2022",numberOfDownloads:2231,editors:[{id:"158026",title:"Prof.",name:"Shailendra K.",middleName:null,surname:"Saxena",slug:"shailendra-k.-saxena",fullName:"Shailendra K. Saxena"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}}],latestBooks:[{type:"book",id:"10755",title:"Corporate Governance",subtitle:"Recent Advances and Perspectives",isOpenForSubmission:!1,hash:"ffe06d1d5c4bf0fc2e63511825fe1257",slug:"corporate-governance-recent-advances-and-perspectives",bookSignature:"Okechukwu Lawrence Emeagwali and Feyza Bhatti",coverURL:"https://cdn.intechopen.com/books/images_new/10755.jpg",editedByType:"Edited by",publishedDate:"June 23rd 2022",editors:[{id:"196317",title:"Associate Prof.",name:"Okechukwu Lawrence",middleName:null,surname:"Emeagwali",slug:"okechukwu-lawrence-emeagwali",fullName:"Okechukwu Lawrence Emeagwali"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11029",title:"Hepatitis B",subtitle:null,isOpenForSubmission:!1,hash:"609701f502efc3538c112ff47a2c2119",slug:"hepatitis-b",bookSignature:"Luis Rodrigo",coverURL:"https://cdn.intechopen.com/books/images_new/11029.jpg",editedByType:"Edited by",publishedDate:"June 23rd 2022",editors:[{id:"73208",title:"Prof.",name:"Luis",middleName:null,surname:"Rodrigo",slug:"luis-rodrigo",fullName:"Luis Rodrigo"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10774",title:"Model Organisms in Plant Genetics",subtitle:null,isOpenForSubmission:!1,hash:"f6624b58571ac10c9b636c5d85ec5e54",slug:"model-organisms-in-plant-genetics",bookSignature:"Ibrokhim Y. Abdurakhmonov",coverURL:"https://cdn.intechopen.com/books/images_new/10774.jpg",editedByType:"Edited by",publishedDate:"June 23rd 2022",editors:[{id:"213344",title:"Prof.",name:"Ibrokhim Y.",middleName:null,surname:"Abdurakhmonov",slug:"ibrokhim-y.-abdurakhmonov",fullName:"Ibrokhim Y. Abdurakhmonov"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11332",title:"Essential Oils",subtitle:"Advances in Extractions and Biological Applications",isOpenForSubmission:!1,hash:"742e6cae3a35686f975edc8d7f9afa94",slug:"essential-oils-advances-in-extractions-and-biological-applications",bookSignature:"Mozaniel Santana de Oliveira and Eloisa Helena de Aguiar Andrade",coverURL:"https://cdn.intechopen.com/books/images_new/11332.jpg",editedByType:"Edited by",publishedDate:"June 23rd 2022",editors:[{id:"195290",title:"Ph.D.",name:"Mozaniel",middleName:null,surname:"Santana De Oliveira",slug:"mozaniel-santana-de-oliveira",fullName:"Mozaniel Santana De Oliveira"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11080",title:"Engineering Principles",subtitle:"Welding and Residual Stresses",isOpenForSubmission:!1,hash:"6c07a13a113bce94174b40096f30fb5e",slug:"engineering-principles-welding-and-residual-stresses",bookSignature:"Kavian Omar Cooke and Ronaldo Câmara Cozza",coverURL:"https://cdn.intechopen.com/books/images_new/11080.jpg",editedByType:"Edited by",publishedDate:"June 23rd 2022",editors:[{id:"138778",title:"Dr.",name:"Kavian",middleName:"Omar",surname:"Cooke",slug:"kavian-cooke",fullName:"Kavian Cooke"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10839",title:"Protein Detection",subtitle:null,isOpenForSubmission:!1,hash:"2f1c0e4e0207fc45c936e7d22a5369c4",slug:"protein-detection",bookSignature:"Yusuf Tutar and Lütfi Tutar",coverURL:"https://cdn.intechopen.com/books/images_new/10839.jpg",editedByType:"Edited by",publishedDate:"June 23rd 2022",editors:[{id:"158492",title:"Prof.",name:"Yusuf",middleName:null,surname:"Tutar",slug:"yusuf-tutar",fullName:"Yusuf Tutar"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10858",title:"MOOC (Massive Open Online Courses)",subtitle:null,isOpenForSubmission:!1,hash:"d32f86793bc72dde32532f509b1ec5b0",slug:"mooc-massive-open-online-courses-",bookSignature:"Dragan Cvetković",coverURL:"https://cdn.intechopen.com/books/images_new/10858.jpg",editedByType:"Edited by",publishedDate:"June 23rd 2022",editors:[{id:"101330",title:"Dr.",name:"Dragan",middleName:"Mladen",surname:"Cvetković",slug:"dragan-cvetkovic",fullName:"Dragan Cvetković"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11371",title:"Cerebral Circulation",subtitle:"Updates on Models, Diagnostics and Treatments of Related Diseases",isOpenForSubmission:!1,hash:"e2d3335445d2852d0b906bb9750e939f",slug:"cerebral-circulation-updates-on-models-diagnostics-and-treatments-of-related-diseases",bookSignature:"Alba Scerrati, Luca Ricciardi and Flavia Dones",coverURL:"https://cdn.intechopen.com/books/images_new/11371.jpg",editedByType:"Edited by",publishedDate:"June 23rd 2022",editors:[{id:"182614",title:"Dr.",name:"Alba",middleName:null,surname:"Scerrati",slug:"alba-scerrati",fullName:"Alba Scerrati"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11120",title:"Environmental Impact and Remediation of Heavy Metals",subtitle:null,isOpenForSubmission:!1,hash:"9e77514288e7394f1e6cd13481af3509",slug:"environmental-impact-and-remediation-of-heavy-metals",bookSignature:"Hosam M. Saleh and Amal I. Hassan",coverURL:"https://cdn.intechopen.com/books/images_new/11120.jpg",editedByType:"Edited by",publishedDate:"June 23rd 2022",editors:[{id:"144691",title:"Prof.",name:"Hosam M.",middleName:null,surname:"Saleh",slug:"hosam-m.-saleh",fullName:"Hosam M. Saleh"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10696",title:"Applications of Calorimetry",subtitle:null,isOpenForSubmission:!1,hash:"8c87f7e2199db33b5dd7181f56973a97",slug:"applications-of-calorimetry",bookSignature:"José Luis Rivera Armenta and Cynthia Graciela Flores Hernández",coverURL:"https://cdn.intechopen.com/books/images_new/10696.jpg",editedByType:"Edited by",publishedDate:"June 23rd 2022",editors:[{id:"107855",title:"Dr.",name:"Jose Luis",middleName:null,surname:"Rivera Armenta",slug:"jose-luis-rivera-armenta",fullName:"Jose Luis Rivera Armenta"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}]},subject:{topic:{id:"1104",title:"Pathophysiology",slug:"medicine-pathology-pathophysiology",parent:{id:"193",title:"Pathology",slug:"medicine-pathology"},numberOfBooks:2,numberOfSeries:0,numberOfAuthorsAndEditors:50,numberOfWosCitations:19,numberOfCrossrefCitations:20,numberOfDimensionsCitations:34,videoUrl:null,fallbackUrl:null,description:null},booksByTopicFilter:{topicId:"1104",sort:"-publishedDate",limit:12,offset:0},booksByTopicCollection:[{type:"book",id:"7009",title:"Hypoxia and Anoxia",subtitle:null,isOpenForSubmission:!1,hash:"80148bd84e86e5fe1c7527637e8e3be8",slug:"hypoxia-and-anoxia",bookSignature:"Kusal K. Das and Mallanagouda Shivanagouda Biradar",coverURL:"https://cdn.intechopen.com/books/images_new/7009.jpg",editedByType:"Edited by",editors:[{id:"187859",title:"Prof.",name:"Kusal",middleName:"K.",surname:"Das",slug:"kusal-das",fullName:"Kusal Das"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"5906",title:"Pathophysiology",subtitle:"Altered Physiological States",isOpenForSubmission:!1,hash:"b277409ee570d9c47798ff5b42638603",slug:"pathophysiology-altered-physiological-states",bookSignature:"David C. Gaze",coverURL:"https://cdn.intechopen.com/books/images_new/5906.jpg",editedByType:"Edited by",editors:[{id:"71983",title:"Dr.",name:"David C.",middleName:null,surname:"Gaze",slug:"david-c.-gaze",fullName:"David C. Gaze"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],booksByTopicTotal:2,seriesByTopicCollection:[],seriesByTopicTotal:0,mostCitedChapters:[{id:"63036",doi:"10.5772/intechopen.80226",title:"Glycolysis Fermentative By-Products and Secondary Metabolites Involved in Plant Adaptation under Hypoxia during Pre- and Postharvest",slug:"glycolysis-fermentative-by-products-and-secondary-metabolites-involved-in-plant-adaptation-under-hyp",totalDownloads:954,totalCrossrefCites:3,totalDimensionsCites:5,abstract:"Floods inducing hypoxia (reduction of available O2) in the plants are current major constrains for agricultural production. Oxygen deficiency in the plant cells induces the secondary response of anatomical and physiological modifications. Hypoxia triggers glycolysis fermentative pathway and other alternative pathways, when the plant lacks energy. During cultivation, some submerged plants can adapt themselves to survive by modifying some parenchyma cells in the roots to be aerenchyma cells to detain available oxygen for oxidative phosphorylation. Furthermore, carbon sources in the cells will be accumulated in N store that recovers back to a C source at the end of hypoxia. In postharvest, long period in modified atmosphere storage could activate hypoxia in the plant parts that produce off-flavor perception. However, in some fruits at a particular maturity, ethanol, a hypoxic product, can be modified into ethyl ester compounds as the detoxification.",book:{id:"7009",slug:"hypoxia-and-anoxia",title:"Hypoxia and Anoxia",fullTitle:"Hypoxia and Anoxia"},signatures:"Chalermchai Wongs-Aree and Sompoch Noichinda",authors:[{id:"252240",title:"Dr.",name:"Sompoch",middleName:null,surname:"Noichinda",slug:"sompoch-noichinda",fullName:"Sompoch Noichinda"},{id:"253569",title:"Dr.",name:"Chalermchai",middleName:null,surname:"Wongs-Aree",slug:"chalermchai-wongs-aree",fullName:"Chalermchai Wongs-Aree"}]},{id:"57416",doi:"10.5772/intechopen.70599",title:"Alteration in Nasal Cycle Rhythm as an Index of the Diseased Condition",slug:"alteration-in-nasal-cycle-rhythm-as-an-index-of-the-diseased-condition",totalDownloads:1384,totalCrossrefCites:5,totalDimensionsCites:5,abstract:"Breathing is the vital function based on the conductance of air through a system of branching tubes that taper off and eventually connect to the alveoli. Nose act as an interface between atmospheric air and lower respiratory system, constitute the moist respiratory epithelium, which performs various vital physiological functions like filtering the inspired air, warming, and humidifying. Several anatomical and physiological factors are responsible for the passage of airflow in two nostrils, which are asymmetric in nature. The inequality airflow passage in both the nostrils exists for a specific duration. This phenomenon of altering asymmetrical airflow from one nasal passage to the other is called ‘nasal cycle’. For every regular interval of time period, the swap of predominant nasal airflow between two nostrils determines the nasal patency. This cycle is controlled by the central regulator located at hypothalamus by coordinating the autonomic nervous system that comprises sympathetic and parasympathetic nerves that clog the nasal mucosa. The nostril decongest when the sympathetic nerves in one nostril become active. In this biorhythm, if the sympathetic nerves of one nostril drop, immediately the parasympathetic nerves take over, so that the other nostril congests. It is unclear why these cycles exist but the total nasal airway resistance is almost unchanged. There are a range of activities and reflexes, which can affect the nasal airway. This biorhythm is categorized under ultradian cycle since the mean duration of nasal cycle is about two and a half hours. In this study, it observed changes in nasal airflow duration, pattern, and rhythm that correspond to various disease states in human.",book:{id:"5906",slug:"pathophysiology-altered-physiological-states",title:"Pathophysiology",fullTitle:"Pathophysiology - Altered Physiological States"},signatures:"Elangovan Muthu Kumaran",authors:[{id:"205096",title:"Dr.",name:"E.",middleName:null,surname:"Muthu Kumaran",slug:"e.-muthu-kumaran",fullName:"E. Muthu Kumaran"}]},{id:"63092",doi:"10.5772/intechopen.80456",title:"Hypoxia Signaling in Cardiovascular Diseases",slug:"hypoxia-signaling-in-cardiovascular-diseases",totalDownloads:1258,totalCrossrefCites:2,totalDimensionsCites:4,abstract:"Cardiovascular diseases such as stroke, coronary artery disease, and thrombosis remain a global health burden. Understanding the mechanism of these diseases paves the way for development of prophylactics/therapeutics. It is well known at cellular levels; the pathophysiology of most of the cardiovascular disease involves a complicated yet coordinated signaling networks triggered in response to either cellular or tissue levels of hypoxic milieu. Information related to types of hypoxia and signaling mechanism associated to such complications if complied and presented in a comprehensive manner shall prove relevant in proposing common therapeutic targets for wide array of cardiovascular complications. The relative functional roles of hypoxia-triggered signaling pathways are also an area of current research. Based upon these facts, this chapter discusses the types of hypoxia and role of hypoxia-mediated signaling pathways in various types of commonly occurring cardiovascular disorders.",book:{id:"7009",slug:"hypoxia-and-anoxia",title:"Hypoxia and Anoxia",fullTitle:"Hypoxia and Anoxia"},signatures:"Neha Gupta and Mohammad Zahid Ashraf",authors:[{id:"237259",title:"Prof.",name:"Mohammad Zahid",middleName:"Zahid",surname:"Ashraf",slug:"mohammad-zahid-ashraf",fullName:"Mohammad Zahid Ashraf"},{id:"246598",title:"Dr.",name:"Neha",middleName:null,surname:"Gupta",slug:"neha-gupta",fullName:"Neha Gupta"}]},{id:"55194",doi:"10.5772/intechopen.68725",title:"Transthyretin in the Evaluation of Health and Disease in Human and Veterinary Medicine",slug:"transthyretin-in-the-evaluation-of-health-and-disease-in-human-and-veterinary-medicine",totalDownloads:1093,totalCrossrefCites:1,totalDimensionsCites:4,abstract:"Transthyretin (also known as prealbumin) is an important transport protein, which plays an essential role in the binding of thyroid hormones and retinol with varying affinities in mammalian, as well as avian species. The determination of transthyretin concentrations may be used as a diagnostic tool for some disease conditions in humans, but is more often used as a nutritional marker to assess protein-calorie malnutrition and as prognostic indicator in critically ill patients. Transthyretin has shorter half-life (2–3 days) than that of albumin and belongs to negative acute phase proteins. This may complicate the use of transthyretin as a nutritional marker and the interpretation of results in the diagnosis of diseases. Although some studies have been carried out to determine the usefulness of transthyretin in selected disease conditions and disorders also in animals, it is a relatively rarely used parameter to evaluate health state and illness in veterinary medicine. The usefulness of transthyretin in the diagnosis of diseases and evaluation of nutritional status in humans and animals are reviewed in this article, including the laboratory assays available to measure its concentrations and the possible clinical application of the results, as well as its usefulness as a prognostic indicator in some disease conditions.",book:{id:"5906",slug:"pathophysiology-altered-physiological-states",title:"Pathophysiology",fullTitle:"Pathophysiology - Altered Physiological States"},signatures:"Csilla Tóthová and Oskar Nagy",authors:[{id:"47101",title:"Prof.",name:"Oskar",middleName:null,surname:"Nagy",slug:"oskar-nagy",fullName:"Oskar Nagy"},{id:"62758",title:"Dr.",name:"Csilla",middleName:null,surname:"Tothova",slug:"csilla-tothova",fullName:"Csilla Tothova"}]},{id:"60898",doi:"10.5772/intechopen.76446",title:"Body Dysmorphic Disorder: Characteristics, Psychopathology, Clinical Associations, and Influencing Factors",slug:"body-dysmorphic-disorder-characteristics-psychopathology-clinical-associations-and-influencing-facto",totalDownloads:1430,totalCrossrefCites:2,totalDimensionsCites:3,abstract:"Body dysmorphic disorder (BDD) is defined by a recurring and persistent concern characterized by psychic suffering caused by a possible physical imperfection in appearance. It is a severe psychiatric condition, duly confirmed by neuroanatomical findings, very peculiar repetitive behaviors, and specific personalities. The prevalence of BDD is increasing around the world and differs between countries, because of cultural differences and different health-care systems. This increase is worrying because BDD is a pathology that presents comorbidity like severe depression, suicidal ideation, and functional and social impairment. However, BDD is an unrecognized and often not diagnosed in our society. Many patients are ashamed of their complaints and do not usually seek psychiatric help with ease, and unfortunately, they seek help in cosmetic and surgical treatments to improve their appearance, and these professionals are not yet prepared to assist in the diagnosis of this disorder. Therefore, this chapter presents not only the psychopathology of BDD but also its associations with other pathologies and their main factors of influence. Finally, we present a clinical experience with a detailed description of a clinical case. The aim is to contribute to the diagnosis and treatment of this pathology and also to future research that may benefit society and these patients.",book:{id:"5906",slug:"pathophysiology-altered-physiological-states",title:"Pathophysiology",fullTitle:"Pathophysiology - Altered Physiological States"},signatures:"Patricia Tatiana Soler, Cristina Michiko Harada Ferreira, Jefferson da\nSilva Novaes and Helder Miguel Fernandes",authors:[{id:"110403",title:"Prof.",name:"Helder",middleName:"Miguel",surname:"Fernandes",slug:"helder-fernandes",fullName:"Helder Fernandes"},{id:"215707",title:"MSc.",name:"Patricia Tatiana",middleName:null,surname:"Soler",slug:"patricia-tatiana-soler",fullName:"Patricia Tatiana Soler"},{id:"215708",title:"Prof.",name:"Jefferson Da Silva",middleName:null,surname:"Novaes",slug:"jefferson-da-silva-novaes",fullName:"Jefferson Da Silva Novaes"},{id:"215709",title:"Dr.",name:"Cristina Michiko Harada",middleName:null,surname:"Ferreira",slug:"cristina-michiko-harada-ferreira",fullName:"Cristina Michiko Harada Ferreira"}]}],mostDownloadedChaptersLast30Days:[{id:"60898",title:"Body Dysmorphic Disorder: Characteristics, Psychopathology, Clinical Associations, and Influencing Factors",slug:"body-dysmorphic-disorder-characteristics-psychopathology-clinical-associations-and-influencing-facto",totalDownloads:1430,totalCrossrefCites:2,totalDimensionsCites:3,abstract:"Body dysmorphic disorder (BDD) is defined by a recurring and persistent concern characterized by psychic suffering caused by a possible physical imperfection in appearance. It is a severe psychiatric condition, duly confirmed by neuroanatomical findings, very peculiar repetitive behaviors, and specific personalities. The prevalence of BDD is increasing around the world and differs between countries, because of cultural differences and different health-care systems. This increase is worrying because BDD is a pathology that presents comorbidity like severe depression, suicidal ideation, and functional and social impairment. However, BDD is an unrecognized and often not diagnosed in our society. Many patients are ashamed of their complaints and do not usually seek psychiatric help with ease, and unfortunately, they seek help in cosmetic and surgical treatments to improve their appearance, and these professionals are not yet prepared to assist in the diagnosis of this disorder. Therefore, this chapter presents not only the psychopathology of BDD but also its associations with other pathologies and their main factors of influence. Finally, we present a clinical experience with a detailed description of a clinical case. The aim is to contribute to the diagnosis and treatment of this pathology and also to future research that may benefit society and these patients.",book:{id:"5906",slug:"pathophysiology-altered-physiological-states",title:"Pathophysiology",fullTitle:"Pathophysiology - Altered Physiological States"},signatures:"Patricia Tatiana Soler, Cristina Michiko Harada Ferreira, Jefferson da\nSilva Novaes and Helder Miguel Fernandes",authors:[{id:"110403",title:"Prof.",name:"Helder",middleName:"Miguel",surname:"Fernandes",slug:"helder-fernandes",fullName:"Helder Fernandes"},{id:"215707",title:"MSc.",name:"Patricia Tatiana",middleName:null,surname:"Soler",slug:"patricia-tatiana-soler",fullName:"Patricia Tatiana Soler"},{id:"215708",title:"Prof.",name:"Jefferson Da Silva",middleName:null,surname:"Novaes",slug:"jefferson-da-silva-novaes",fullName:"Jefferson Da Silva Novaes"},{id:"215709",title:"Dr.",name:"Cristina Michiko Harada",middleName:null,surname:"Ferreira",slug:"cristina-michiko-harada-ferreira",fullName:"Cristina Michiko Harada Ferreira"}]},{id:"59625",title:"An Overview on Prostate Pathophysiology: New Insights into Prostate Cancer Clinical Diagnosis",slug:"an-overview-on-prostate-pathophysiology-new-insights-into-prostate-cancer-clinical-diagnosis",totalDownloads:1574,totalCrossrefCites:2,totalDimensionsCites:2,abstract:"The prostate is an accessory gland of the male reproductive tract, and its presence is universal in mammals. It is committed to the prostatic fluid production and storage, which is released with other semen components during ejaculation. Such fluid contributes to increasing motility and fertility of the spermatozoa, and the neutralization of the vagina, thus playing an important role in fertilization. Few pathological complications, often progressively aggravated with age, can affect this gland (i.e. benign and malignant proliferative changes; all to be described next in this chapter). Nowadays, the neoplastic expansion is the main motivator and contributor for studies on enlightening of growth regulation mechanisms and physiology of the prostate.",book:{id:"5906",slug:"pathophysiology-altered-physiological-states",title:"Pathophysiology",fullTitle:"Pathophysiology - Altered Physiological States"},signatures:"Gustavo Ferreira Simoes, Paula Sakuramoto, Caroline Brito dos\nSantos, Nilva Karla Cervigne Furlan and Taize Machado Augusto",authors:[{id:"219765",title:"Dr.",name:"Taize",middleName:"Machado",surname:"Augusto",slug:"taize-augusto",fullName:"Taize Augusto"},{id:"222944",title:"Dr.",name:"Gustavo",middleName:null,surname:"Simoes",slug:"gustavo-simoes",fullName:"Gustavo Simoes"},{id:"222945",title:"Dr.",name:"Nilva",middleName:null,surname:"Cervigne",slug:"nilva-cervigne",fullName:"Nilva Cervigne"},{id:"222946",title:"Ms.",name:"Paula",middleName:null,surname:"Sakuramoto",slug:"paula-sakuramoto",fullName:"Paula Sakuramoto"},{id:"222947",title:"Ms.",name:"Caroline",middleName:null,surname:"Santos",slug:"caroline-santos",fullName:"Caroline Santos"}]},{id:"63036",title:"Glycolysis Fermentative By-Products and Secondary Metabolites Involved in Plant Adaptation under Hypoxia during Pre- and Postharvest",slug:"glycolysis-fermentative-by-products-and-secondary-metabolites-involved-in-plant-adaptation-under-hyp",totalDownloads:954,totalCrossrefCites:3,totalDimensionsCites:5,abstract:"Floods inducing hypoxia (reduction of available O2) in the plants are current major constrains for agricultural production. Oxygen deficiency in the plant cells induces the secondary response of anatomical and physiological modifications. Hypoxia triggers glycolysis fermentative pathway and other alternative pathways, when the plant lacks energy. During cultivation, some submerged plants can adapt themselves to survive by modifying some parenchyma cells in the roots to be aerenchyma cells to detain available oxygen for oxidative phosphorylation. Furthermore, carbon sources in the cells will be accumulated in N store that recovers back to a C source at the end of hypoxia. In postharvest, long period in modified atmosphere storage could activate hypoxia in the plant parts that produce off-flavor perception. However, in some fruits at a particular maturity, ethanol, a hypoxic product, can be modified into ethyl ester compounds as the detoxification.",book:{id:"7009",slug:"hypoxia-and-anoxia",title:"Hypoxia and Anoxia",fullTitle:"Hypoxia and Anoxia"},signatures:"Chalermchai Wongs-Aree and Sompoch Noichinda",authors:[{id:"252240",title:"Dr.",name:"Sompoch",middleName:null,surname:"Noichinda",slug:"sompoch-noichinda",fullName:"Sompoch Noichinda"},{id:"253569",title:"Dr.",name:"Chalermchai",middleName:null,surname:"Wongs-Aree",slug:"chalermchai-wongs-aree",fullName:"Chalermchai Wongs-Aree"}]},{id:"62932",title:"Introductory Chapter: Primary Concept of Hypoxia and Anoxia",slug:"introductory-chapter-primary-concept-of-hypoxia-and-anoxia",totalDownloads:1208,totalCrossrefCites:1,totalDimensionsCites:3,abstract:null,book:{id:"7009",slug:"hypoxia-and-anoxia",title:"Hypoxia and Anoxia",fullTitle:"Hypoxia and Anoxia"},signatures:"Shrilaxmi Bagali, Gavishsidappa A. Hadimani, Mallanagouda S. Biradar and Kusal K. Das",authors:[{id:"187859",title:"Prof.",name:"Kusal",middleName:"K.",surname:"Das",slug:"kusal-das",fullName:"Kusal Das"},{id:"188854",title:"Prof.",name:"M.S.",middleName:null,surname:"Biradar",slug:"m.s.-biradar",fullName:"M.S. Biradar"},{id:"263841",title:"Dr.",name:"Shrilaxmi",middleName:null,surname:"Bagali",slug:"shrilaxmi-bagali",fullName:"Shrilaxmi Bagali"},{id:"265434",title:"Dr.",name:"Gavishiddappa A.",middleName:null,surname:"Hadimani",slug:"gavishiddappa-a.-hadimani",fullName:"Gavishiddappa A. Hadimani"}]},{id:"59825",title:"Polycystic Ovary Syndrome, Pathophysiology, and Reproductive Health Implications",slug:"polycystic-ovary-syndrome-pathophysiology-and-reproductive-health-implications",totalDownloads:1441,totalCrossrefCites:1,totalDimensionsCites:1,abstract:"Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women of reproductive age. The clinical picture characterized by both endocrine disorders (hyperandrogenism, menstrual cycle disorders, obesity) and metabolic alteration with implications for women’s health and reproductive and metabolic consequences. Leventhal described for the first time a syndrome characterized by polycystic ovaries associated with menstrual cycle disorders, hirsutism, and obesity. The pathophysiology and other metabolic disorders that make the PCOS more complex than originally described are the most common cause of infertility linked to chronic anovulation. In fact, this is a multifactorial disorder that involves the hypothalamus, pituitary, ovary, adrenal, and peripheral adipose tissues, which are simultaneously involved in the pathogenesis of the syndrome.",book:{id:"5906",slug:"pathophysiology-altered-physiological-states",title:"Pathophysiology",fullTitle:"Pathophysiology - Altered Physiological States"},signatures:"Bassim Alsadi",authors:[{id:"204687",title:"Ph.D.",name:"Bassim",middleName:null,surname:"Alsadi",slug:"bassim-alsadi",fullName:"Bassim Alsadi"}]}],onlineFirstChaptersFilter:{topicId:"1104",limit:6,offset:0},onlineFirstChaptersCollection:[],onlineFirstChaptersTotal:0},preDownload:{success:null,errors:{}},subscriptionForm:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[],offset:8,limit:8,total:0},allSeries:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:9,numberOfPublishedChapters:89,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:104,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:31,numberOfPublishedChapters:314,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:11,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:11,numberOfPublishedChapters:141,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:8,numberOfPublishedChapters:129,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!0},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:113,numberOfOpenTopics:3,numberOfUpcomingTopics:1,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:11,numberOfPublishedChapters:105,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:17,numberOfOpenTopics:2,numberOfUpcomingTopics:1,issn:"2753-894X",doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:5,numberOfOpenTopics:1,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!0},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:0,numberOfPublishedChapters:14,numberOfOpenTopics:5,numberOfUpcomingTopics:0,issn:null,doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],testimonialsList:[{id:"6",text:"It is great to work with the IntechOpen to produce a worthwhile collection of research that also becomes a great educational resource and guide for future research endeavors.",author:{id:"259298",name:"Edward",surname:"Narayan",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259298/images/system/259298.jpeg",slug:"edward-narayan",institution:{id:"3",name:"University of Queensland",country:{id:null,name:"Australia"}}}},{id:"13",text:"The collaboration with and support of the technical staff of IntechOpen is fantastic. The whole process of submitting an article and editing of the submitted article goes extremely smooth and fast, the number of reads and downloads of chapters is high, and the contributions are also frequently cited.",author:{id:"55578",name:"Antonio",surname:"Jurado-Navas",institutionString:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRisIQAS/Profile_Picture_1626166543950",slug:"antonio-jurado-navas",institution:{id:"720",name:"University of Malaga",country:{id:null,name:"Spain"}}}}]},series:{item:{id:"23",title:"Education and Human Development",doi:"10.5772/intechopen.100360",issn:null,scope:"\r\n\tEducation and Human Development is an interdisciplinary research area that aims to shed light on topics related to both learning and development. This Series is intended for researchers, practitioners, and students who are interested in understanding more about these fields and their applications.
",coverUrl:"https://cdn.intechopen.com/series/covers/23.jpg",latestPublicationDate:"June 25th, 2022",hasOnlineFirst:!0,numberOfPublishedBooks:0,editor:{id:"280770",title:"Dr.",name:"Katherine K.M.",middleName:null,surname:"Stavropoulos",slug:"katherine-k.m.-stavropoulos",fullName:"Katherine K.M. Stavropoulos",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRdFuQAK/Profile_Picture_2022-05-24T09:03:48.jpg",biography:"Katherine Stavropoulos received her BA in Psychology from Trinity College, in Connecticut, USA. Dr. Stavropoulos received her Ph.D. in Experimental Psychology from the University of California, San Diego. She completed her postdoctoral work at the Yale Child Study Center with Dr. James McPartland. Dr. Stavropoulos’ doctoral dissertation explored neural correlates of reward anticipation to social versus nonsocial stimuli in children with and without autism spectrum disorders (ASD). She has been a faculty member at the University of California, Riverside in the School of Education since 2016. Her research focuses on translational studies to explore the reward system in ASD, as well as how anxiety contributes to social challenges in ASD. She also investigates how behavioral interventions affect neural activity, behavior, and school performance in children with ASD. She is also involved in the diagnosis of children with ASD and is a licensed clinical psychologist in California. She is the Assistant Director of the SEARCH Center at UCR and is a Faculty member in the Graduate Program in Neuroscience.",institutionString:null,institution:{name:"University of California, Riverside",institutionURL:null,country:{name:"United States of America"}}},editorTwo:null,editorThree:null},subseries:{paginationCount:2,paginationItems:[{id:"89",title:"Education",coverUrl:"https://cdn.intechopen.com/series_topics/covers/89.jpg",isOpenForSubmission:!1,editor:{id:"260066",title:"Associate Prof.",name:"Michail",middleName:null,surname:"Kalogiannakis",slug:"michail-kalogiannakis",fullName:"Michail Kalogiannakis",profilePictureURL:"https://mts.intechopen.com/storage/users/260066/images/system/260066.jpg",biography:"Michail Kalogiannakis is an Associate Professor of the Department of Preschool Education, University of Crete, and an Associate Tutor at School of Humanities at the Hellenic Open University. He graduated from the Physics Department of the University of Crete and continued his post-graduate studies at the University Paris 7-Denis Diderot (D.E.A. in Didactic of Physics), University Paris 5-René Descartes-Sorbonne (D.E.A. in Science Education) and received his Ph.D. degree at the University Paris 5-René Descartes-Sorbonne (PhD in Science Education). His research interests include science education in early childhood, science teaching and learning, e-learning, the use of ICT in science education, games simulations, and mobile learning. He has published over 120 articles in international conferences and journals and has served on the program committees of numerous international conferences.",institutionString:"University of Crete",institution:{name:"University of Crete",institutionURL:null,country:{name:"Greece"}}},editorTwo:{id:"422488",title:"Dr.",name:"Maria",middleName:null,surname:"Ampartzaki",slug:"maria-ampartzaki",fullName:"Maria Ampartzaki",profilePictureURL:"https://mts.intechopen.com/storage/users/422488/images/system/422488.jpg",biography:"Dr Maria Ampartzaki is an Assistant Professor in Early Childhood Education in the Department of Preschool Education at the University of Crete. Her research interests include ICT in education, science education in the early years, inquiry-based and art-based learning, teachers’ professional development, action research, and the Pedagogy of Multiliteracies, among others. She has run and participated in several funded and non-funded projects on the teaching of Science, Social Sciences, and ICT in education. She also has the experience of participating in five Erasmus+ projects.",institutionString:"University of Crete",institution:{name:"University of Crete",institutionURL:null,country:{name:"Greece"}}},editorThree:null},{id:"90",title:"Human Development",coverUrl:"https://cdn.intechopen.com/series_topics/covers/90.jpg",isOpenForSubmission:!0,editor:{id:"191040",title:"Dr.",name:"Tal",middleName:null,surname:"Dotan Ben-Soussan",slug:"tal-dotan-ben-soussan",fullName:"Tal Dotan Ben-Soussan",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSBf1QAG/Profile_Picture_2022-03-18T07:56:11.jpg",biography:"Tal Dotan Ben-Soussan, Ph.D., is the director of the Research Institute for Neuroscience, Education and Didactics (RINED) – Paoletti Foundation. Ben-Soussan leads international studies on training and neuroplasticity from neurophysiological and psychobiological perspectives. As a neuroscientist and bio-psychologist, she has published numerous articles on neuroplasticity, movement and meditation. She acts as an editor and reviewer in several renowned journals and coordinates international conferences integrating theoretical, methodological and practical approaches on various topics, such as silence, logics and neuro-education. She lives in Assisi, Italy.",institutionString:"Research Institute for Neuroscience, Education and Didactics, Patrizio Paoletti Foundation",institution:null},editorTwo:null,editorThree:null}]},overviewPageOFChapters:{paginationCount:5,paginationItems:[{id:"82394",title:"Learning by Doing Active Social Learning",doi:"10.5772/intechopen.105523",signatures:"Anat Raviv",slug:"learning-by-doing-active-social-learning",totalDownloads:1,totalCrossrefCites:null,totalDimensionsCites:null,authors:null,book:{title:"Active Learning - Research and Practice",coverURL:"https://cdn.intechopen.com/books/images_new/11481.jpg",subseries:{id:"89",title:"Education"}}},{id:"82310",title:"Knowledge of Intergenerational Contact to Combat Ageism towards Older People",doi:"10.5772/intechopen.105592",signatures:"Alice Nga Lai Kwong",slug:"knowledge-of-intergenerational-contact-to-combat-ageism-towards-older-people",totalDownloads:7,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Social Aspects of Ageing - Selected Challenges, Analyses, and Solutions",coverURL:"https://cdn.intechopen.com/books/images_new/11479.jpg",subseries:{id:"90",title:"Human Development"}}},{id:"81993",title:"Emergent Chemistry: Using Visualizations to Develop Abstract Thinking and a Sense of Scale Within the Preschool Setting",doi:"10.5772/intechopen.105216",signatures:"Karina Adbo",slug:"emergent-chemistry-using-visualizations-to-develop-abstract-thinking-and-a-sense-of-scale-within-the",totalDownloads:3,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Active Learning - Research and Practice",coverURL:"https://cdn.intechopen.com/books/images_new/11481.jpg",subseries:{id:"89",title:"Education"}}},{id:"82252",title:"Early Childhood: Enriched Environments and Roles of Caring Adults",doi:"10.5772/intechopen.105157",signatures:"Analía Mignaton",slug:"early-childhood-enriched-environments-and-roles-of-caring-adults",totalDownloads:4,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Active Learning - Research and Practice",coverURL:"https://cdn.intechopen.com/books/images_new/11481.jpg",subseries:{id:"89",title:"Education"}}}]},overviewPagePublishedBooks:{paginationCount:0,paginationItems:[]},openForSubmissionBooks:{paginationCount:3,paginationItems:[{id:"11578",title:"Antibiotics and Probiotics in Animal Food - Impact and Regulation",coverURL:"https://cdn.intechopen.com/books/images_new/11578.jpg",hash:"3731c009f474c6ed4293f348ca7b27ac",secondStepPassed:!0,currentStepOfPublishingProcess:3,submissionDeadline:"June 3rd 2022",isOpenForSubmission:!0,editors:[{id:"225390",title:"Dr.",name:"Asghar Ali",surname:"Kamboh",slug:"asghar-ali-kamboh",fullName:"Asghar Ali Kamboh"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{id:"12086",title:"Cattle Diseases - Molecular and Biochemical Approach",coverURL:"https://cdn.intechopen.com/books/images_new/12086.jpg",hash:"afdbf57e32d996556a94528c06623cf3",secondStepPassed:!1,currentStepOfPublishingProcess:2,submissionDeadline:"July 5th 2022",isOpenForSubmission:!0,editors:[{id:"219081",title:"Dr.",name:"Abdulsamed",surname:"Kükürt",slug:"abdulsamed-kukurt",fullName:"Abdulsamed Kükürt"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{id:"11579",title:"Animal Welfare - New Insights",coverURL:"https://cdn.intechopen.com/books/images_new/11579.jpg",hash:"12e4f41264cbe99028655e5463fa941a",secondStepPassed:!1,currentStepOfPublishingProcess:2,submissionDeadline:"July 8th 2022",isOpenForSubmission:!0,editors:[{id:"51520",title:"Dr.",name:"Shao-Wen",surname:"Hung",slug:"shao-wen-hung",fullName:"Shao-Wen Hung"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null}]},onlineFirstChapters:{paginationCount:45,paginationItems:[{id:"82135",title:"Carotenoids in Cassava (Manihot esculenta Crantz)",doi:"10.5772/intechopen.105210",signatures:"Lovina I. Udoh, Josephine U. Agogbua, Eberechi R. Keyagha and Itorobong I. Nkanga",slug:"carotenoids-in-cassava-manihot-esculenta-crantz",totalDownloads:3,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Carotenoids - New Perspectives and Application",coverURL:"https://cdn.intechopen.com/books/images_new/10836.jpg",subseries:{id:"13",title:"Plant Physiology"}}},{id:"82112",title:"Comparative Senescence and Lifespan",doi:"10.5772/intechopen.105137",signatures:"Hassan M. Heshmati",slug:"comparative-senescence-and-lifespan",totalDownloads:7,totalCrossrefCites:0,totalDimensionsCites:0,authors:[{name:"Hassan M.",surname:"Heshmati"}],book:{title:"Mechanisms and Management of Senescence",coverURL:"https://cdn.intechopen.com/books/images_new/10935.jpg",subseries:{id:"11",title:"Cell Physiology"}}},{id:"81796",title:"Apoptosis-Related Diseases and Peroxisomes",doi:"10.5772/intechopen.105052",signatures:"Meimei Wang, Yakun Liu, Ni Chen, Juan Wang and Ye Zhao",slug:"apoptosis-related-diseases-and-peroxisomes",totalDownloads:11,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"The Metabolic Role of Peroxisome in Health and Disease",coverURL:"https://cdn.intechopen.com/books/images_new/10837.jpg",subseries:{id:"11",title:"Cell Physiology"}}},{id:"81723",title:"Peroxisomal Modulation as Therapeutic Alternative for Tackling Multiple Cancers",doi:"10.5772/intechopen.104873",signatures:"Shazia Usmani, Shadma Wahab, Abdul Hafeez, Shabana Khatoon and Syed Misbahul Hasan",slug:"peroxisomal-modulation-as-therapeutic-alternative-for-tackling-multiple-cancers",totalDownloads:4,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"The Metabolic Role of Peroxisome in Health and Disease",coverURL:"https://cdn.intechopen.com/books/images_new/10837.jpg",subseries:{id:"11",title:"Cell Physiology"}}},{id:"81638",title:"Aging and Neuropsychiatric Disease: A General Overview of Prevalence and Trends",doi:"10.5772/intechopen.103102",signatures:"Jelena Milić",slug:"aging-and-neuropsychiatric-disease-a-general-overview-of-prevalence-and-trends",totalDownloads:24,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Mechanisms and Management of Senescence",coverURL:"https://cdn.intechopen.com/books/images_new/10935.jpg",subseries:{id:"11",title:"Cell Physiology"}}},{id:"81566",title:"New and Emerging Technologies for Integrative Ambulatory Autonomic Assessment and Intervention as a Catalyst in the Synergy of Remote Geocoded Biosensing, Algorithmic Networked Cloud Computing, Deep Learning, and Regenerative/Biomic Medicine: Further Real",doi:"10.5772/intechopen.104092",signatures:"Robert L. Drury",slug:"new-and-emerging-technologies-for-integrative-ambulatory-autonomic-assessment-and-intervention-as-a-",totalDownloads:17,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Autonomic Nervous System - Special Interest Topics",coverURL:"https://cdn.intechopen.com/books/images_new/10835.jpg",subseries:{id:"12",title:"Human Physiology"}}},{id:"81576",title:"Carotenoids in Thermal Adaptation of Plants and Animals",doi:"10.5772/intechopen.104537",signatures:"Ivan M. Petyaev",slug:"carotenoids-in-thermal-adaptation-of-plants-and-animals",totalDownloads:24,totalCrossrefCites:0,totalDimensionsCites:0,authors:[{name:"Ivan",surname:"Petyaev"}],book:{title:"Carotenoids - New Perspectives and Application",coverURL:"https://cdn.intechopen.com/books/images_new/10836.jpg",subseries:{id:"13",title:"Plant Physiology"}}},{id:"81358",title:"New Insights on Carotenoid Production by Gordonia alkanivorans Strain 1B",doi:"10.5772/intechopen.103919",signatures:"Tiago P. Silva, Susana M. Paixão, Ana S. Fernandes, José C. Roseiro and Luís Alves",slug:"new-insights-on-carotenoid-production-by-gordonia-alkanivorans-strain-1b",totalDownloads:16,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Carotenoids - New Perspectives and Application",coverURL:"https://cdn.intechopen.com/books/images_new/10836.jpg",subseries:{id:"13",title:"Plant Physiology"}}},{id:"81298",title:"Roles of Extracellular Vesicles in Cancer Metastasis",doi:"10.5772/intechopen.103798",signatures:"Eman Helmy Thabet",slug:"roles-of-extracellular-vesicles-in-cancer-metastasis",totalDownloads:33,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Extracellular Vesicles - Role in Diseases, Pathogenesis and Therapy",coverURL:"https://cdn.intechopen.com/books/images_new/10796.jpg",subseries:{id:"11",title:"Cell Physiology"}}},{id:"81290",title:"Musculoskeletal Abnormalities Caused by Cystic Fibrosis",doi:"10.5772/intechopen.104591",signatures:"Mark Lambrechts",slug:"musculoskeletal-abnormalities-caused-by-cystic-fibrosis",totalDownloads:23,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Advances in Skeletal Muscle Health and Disease",coverURL:"https://cdn.intechopen.com/books/images_new/11675.jpg",subseries:{id:"11",title:"Cell Physiology"}}}]},subseriesFiltersForOFChapters:[{caption:"Plant Physiology",value:13,count:6,group:"subseries"},{caption:"Human Physiology",value:12,count:13,group:"subseries"},{caption:"Cell Physiology",value:11,count:26,group:"subseries"}],publishedBooks:{paginationCount:11,paginationItems:[{type:"book",id:"10664",title:"Animal Reproduction",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/10664.jpg",slug:"animal-reproduction",publishedDate:"May 25th 2022",editedByType:"Edited by",bookSignature:"Yusuf Bozkurt and Mustafa Numan Bucak",hash:"2d66af42fb17d0a6556bb9ef28e273c7",volumeInSeries:11,fullTitle:"Animal Reproduction",editors:[{id:"90846",title:"Prof.",name:"Yusuf",middleName:null,surname:"Bozkurt",slug:"yusuf-bozkurt",fullName:"Yusuf Bozkurt",profilePictureURL:"https://mts.intechopen.com/storage/users/90846/images/system/90846.jpg",institutionString:"İskenderun Technical University",institution:{name:"İskenderun Technical University",institutionURL:null,country:{name:"Turkey"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"10830",title:"Animal Feed Science and Nutrition",subtitle:"Production, Health and Environment",coverURL:"https://cdn.intechopen.com/books/images_new/10830.jpg",slug:"animal-feed-science-and-nutrition-production-health-and-environment",publishedDate:"May 18th 2022",editedByType:"Edited by",bookSignature:"Amlan Kumar Patra",hash:"79944fc8fbbaa329aed6fde388154832",volumeInSeries:10,fullTitle:"Animal Feed Science and Nutrition - Production, Health and Environment",editors:[{id:"310962",title:"Dr.",name:"Amlan",middleName:"Kumar",surname:"Patra",slug:"amlan-patra",fullName:"Amlan Patra",profilePictureURL:"https://mts.intechopen.com/storage/users/310962/images/system/310962.jpg",institutionString:null,institution:{name:"West Bengal University of Animal and Fishery Sciences",institutionURL:null,country:{name:"India"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"8737",title:"Rabies Virus at the Beginning of 21st Century",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/8737.jpg",slug:"rabies-virus-at-the-beginning-of-21st-century",publishedDate:"May 11th 2022",editedByType:"Edited by",bookSignature:"Sergey Tkachev",hash:"49cce3f548da548c718c865feb343509",volumeInSeries:9,fullTitle:"Rabies Virus at the Beginning of 21st Century",editors:[{id:"61139",title:"Dr.",name:"Sergey",middleName:null,surname:"Tkachev",slug:"sergey-tkachev",fullName:"Sergey Tkachev",profilePictureURL:"https://mts.intechopen.com/storage/users/61139/images/system/61139.png",institutionString:"Russian Academy of Sciences",institution:{name:"Russian Academy of Sciences",institutionURL:null,country:{name:"Russia"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"10496",title:"Advanced Studies in the 21st Century Animal Nutrition",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/10496.jpg",slug:"advanced-studies-in-the-21st-century-animal-nutrition",publishedDate:"December 8th 2021",editedByType:"Edited by",bookSignature:"László Babinszky, Juliana Oliveira and Edson Mauro Santos",hash:"8ffe43a82ac48b309abc3632bbf3efd0",volumeInSeries:8,fullTitle:"Advanced Studies in the 21st Century Animal Nutrition",editors:[{id:"53998",title:"Prof.",name:"László",middleName:null,surname:"Babinszky",slug:"laszlo-babinszky",fullName:"László Babinszky",profilePictureURL:"https://mts.intechopen.com/storage/users/53998/images/system/53998.png",institutionString:"University of Debrecen",institution:{name:"University of Debrecen",institutionURL:null,country:{name:"Hungary"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"10497",title:"Canine Genetics, Health and Medicine",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/10497.jpg",slug:"canine-genetics-health-and-medicine",publishedDate:"June 2nd 2021",editedByType:"Edited by",bookSignature:"Catrin Rutland",hash:"b91512e31ce34032e560362e6cbccc1c",volumeInSeries:7,fullTitle:"Canine Genetics, Health and Medicine",editors:[{id:"202192",title:"Dr.",name:"Catrin",middleName:null,surname:"Rutland",slug:"catrin-rutland",fullName:"Catrin Rutland",profilePictureURL:"https://mts.intechopen.com/storage/users/202192/images/system/202192.png",institutionString:null,institution:{name:"University of Nottingham",institutionURL:null,country:{name:"United Kingdom"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"8545",title:"Animal Reproduction in Veterinary Medicine",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/8545.jpg",slug:"animal-reproduction-in-veterinary-medicine",publishedDate:"January 20th 2021",editedByType:"Edited by",bookSignature:"Faruk Aral, Rita Payan-Carreira and Miguel Quaresma",hash:"13aaddf5fdbbc78387e77a7da2388bf6",volumeInSeries:6,fullTitle:"Animal Reproduction in Veterinary Medicine",editors:[{id:"25600",title:"Prof.",name:"Faruk",middleName:null,surname:"Aral",slug:"faruk-aral",fullName:"Faruk Aral",profilePictureURL:"https://mts.intechopen.com/storage/users/25600/images/system/25600.jpg",institutionString:"Independent Researcher",institution:{name:"Harran University",institutionURL:null,country:{name:"Turkey"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"9081",title:"Equine Science",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/9081.jpg",slug:"equine-science",publishedDate:"September 23rd 2020",editedByType:"Edited by",bookSignature:"Catrin Rutland and Albert Rizvanov",hash:"ac415ef2f5450fa80fdb9cf6cf32cd2d",volumeInSeries:5,fullTitle:"Equine Science",editors:[{id:"202192",title:"Dr.",name:"Catrin",middleName:null,surname:"Rutland",slug:"catrin-rutland",fullName:"Catrin Rutland",profilePictureURL:"https://mts.intechopen.com/storage/users/202192/images/system/202192.png",institutionString:null,institution:{name:"University of Nottingham",institutionURL:null,country:{name:"United Kingdom"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"8460",title:"Reproductive Biology and Technology in Animals",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/8460.jpg",slug:"reproductive-biology-and-technology-in-animals",publishedDate:"April 15th 2020",editedByType:"Edited by",bookSignature:"Juan Carlos Gardón Poggi and Katy Satué Ambrojo",hash:"32ef5fe73998dd723d308225d756fa1e",volumeInSeries:4,fullTitle:"Reproductive Biology and Technology in Animals",editors:[{id:"251314",title:"Dr.",name:"Juan Carlos",middleName:null,surname:"Gardón",slug:"juan-carlos-gardon",fullName:"Juan Carlos Gardón",profilePictureURL:"https://mts.intechopen.com/storage/users/251314/images/system/251314.jpeg",institutionString:"Catholic University of Valencia San Vicente Mártir, Spain",institution:null}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"8524",title:"Lactation in Farm Animals",subtitle:"Biology, Physiological Basis, Nutritional Requirements, and Modelization",coverURL:"https://cdn.intechopen.com/books/images_new/8524.jpg",slug:"lactation-in-farm-animals-biology-physiological-basis-nutritional-requirements-and-modelization",publishedDate:"January 22nd 2020",editedByType:"Edited by",bookSignature:"Naceur M'Hamdi",hash:"2aa2a9a0ec13040bbf0455e34625504e",volumeInSeries:3,fullTitle:"Lactation in Farm Animals - Biology, Physiological Basis, Nutritional Requirements, and Modelization",editors:[{id:"73376",title:"Dr.",name:"Naceur",middleName:null,surname:"M'Hamdi",slug:"naceur-m'hamdi",fullName:"Naceur M'Hamdi",profilePictureURL:"https://mts.intechopen.com/storage/users/73376/images/system/73376.jpg",institutionString:null,institution:null}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"7144",title:"Veterinary Anatomy and Physiology",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7144.jpg",slug:"veterinary-anatomy-and-physiology",publishedDate:"March 13th 2019",editedByType:"Edited by",bookSignature:"Catrin Sian Rutland and Valentina Kubale",hash:"75cdacb570e0e6d15a5f6e69640d87c9",volumeInSeries:2,fullTitle:"Veterinary Anatomy and Physiology",editors:[{id:"202192",title:"Dr.",name:"Catrin",middleName:null,surname:"Rutland",slug:"catrin-rutland",fullName:"Catrin Rutland",profilePictureURL:"https://mts.intechopen.com/storage/users/202192/images/system/202192.png",institutionString:null,institution:{name:"University of Nottingham",institutionURL:null,country:{name:"United Kingdom"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"7233",title:"New Insights into Theriogenology",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7233.jpg",slug:"new-insights-into-theriogenology",publishedDate:"December 5th 2018",editedByType:"Edited by",bookSignature:"Rita Payan-Carreira",hash:"74f4147e3fb214dd050e5edd3aaf53bc",volumeInSeries:1,fullTitle:"New Insights into Theriogenology",editors:[{id:"38652",title:"Prof.",name:"Rita",middleName:null,surname:"Payan-Carreira",slug:"rita-payan-carreira",fullName:"Rita Payan-Carreira",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRiFPQA0/Profile_Picture_1614601496313",institutionString:null,institution:{name:"University of Évora",institutionURL:null,country:{name:"Portugal"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null}]},subseriesFiltersForPublishedBooks:[{group:"subseries",caption:"Animal Nutrition",value:20,count:2},{group:"subseries",caption:"Animal Reproductive Biology and Technology",value:28,count:4},{group:"subseries",caption:"Animal Science",value:19,count:5}],publicationYearFilters:[{group:"publicationYear",caption:"2022",value:2022,count:3},{group:"publicationYear",caption:"2021",value:2021,count:3},{group:"publicationYear",caption:"2020",value:2020,count:3},{group:"publicationYear",caption:"2019",value:2019,count:1},{group:"publicationYear",caption:"2018",value:2018,count:1}],authors:{paginationCount:0,paginationItems:[]}},subseries:{item:{id:"91",type:"subseries",title:"Sustainable Economy and Fair Society",keywords:"Sustainable, Society, Economy, Digitalization, KPIs, Decision Making, Business, Digital Footprint",scope:"\r\n\tGlobally, the ecological footprint is growing at a faster rate than GDP. This phenomenon has been studied by scientists for many years. However, clear strategies and actions are needed now more than ever. Every day, humanity, from individuals to businesses (public and private) and governments, are called to change their mindset in order to pursue a virtuous combination for sustainable development. Reasoning in a sustainable way entails, first and foremost, managing the available resources efficiently and strategically, whether they are natural, financial, human or relational. In this way, value is generated by contributing to the growth, improvement and socio-economic development of the communities and of all the players that make up its value chain. In the coming decades, we will need to be able to transition from a society in which economic well-being and health are measured by the growth of production and material consumption, to a society in which we live better while consuming less. In this context, digitization has the potential to disrupt processes, with significant implications for the environment and sustainable development. There are numerous challenges associated with sustainability and digitization, the need to consider new business models capable of extracting value, data ownership and sharing and integration, as well as collaboration across the entire supply chain of a product. In order to generate value, effectively developing a complex system based on sustainability principles is a challenge that requires a deep commitment to both technological factors, such as data and platforms, and human dimensions, such as trust and collaboration. Regular study, research and implementation must be part of the road to sustainable solutions. Consequently, this topic will analyze growth models and techniques aimed at achieving intergenerational equity in terms of economic, social and environmental well-being. It will also cover various subjects, including risk assessment in the context of sustainable economy and a just society.
",coverUrl:"https://cdn.intechopen.com/series_topics/covers/91.jpg",hasOnlineFirst:!0,hasPublishedBooks:!1,annualVolume:11975,editor:{id:"181603",title:"Dr.",name:"Antonella",middleName:null,surname:"Petrillo",slug:"antonella-petrillo",fullName:"Antonella Petrillo",profilePictureURL:"https://mts.intechopen.com/storage/users/181603/images/system/181603.jpg",biography:"Antonella Petrillo is a Professor at the Department of Engineering of the University of Naples “Parthenope”, Italy. She received her Ph.D. in Mechanical Engineering from the University of Cassino. Her research interests include multi-criteria decision analysis, industrial plant, logistics, manufacturing and safety. She serves as an Associate Editor for the International Journal of the Analytic Hierarchy Process. She is a member of AHP Academy and a member of several editorial boards. She has over 160 Scientific Publications in International Journals and Conferences and she is the author of 5 books on Innovation and Decision Making in Industrial Applications and Engineering.",institutionString:null,institution:{name:"Parthenope University of Naples",institutionURL:null,country:{name:"Italy"}}},editorTwo:null,editorThree:null,series:{id:"24",title:"Sustainable Development",doi:"10.5772/intechopen.100361",issn:null},editorialBoard:[{id:"179628",title:"Prof.",name:"Dima",middleName:null,surname:"Jamali",slug:"dima-jamali",fullName:"Dima Jamali",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSAIlQAO/Profile_Picture_2022-03-07T08:52:23.jpg",institutionString:null,institution:{name:"University of Sharjah",institutionURL:null,country:{name:"United Arab Emirates"}}},{id:"170206",title:"Prof.",name:"Dr. Orhan",middleName:null,surname:"Özçatalbaş",slug:"dr.-orhan-ozcatalbas",fullName:"Dr. Orhan Özçatalbaş",profilePictureURL:"https://mts.intechopen.com/storage/users/170206/images/system/170206.png",institutionString:null,institution:{name:"Akdeniz University",institutionURL:null,country:{name:"Turkey"}}},{id:"250347",title:"Associate Prof.",name:"Isaac",middleName:null,surname:"Oluwatayo",slug:"isaac-oluwatayo",fullName:"Isaac Oluwatayo",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRVIVQA4/Profile_Picture_2022-03-17T13:25:32.jpg",institutionString:null,institution:{name:"University of Venda",institutionURL:null,country:{name:"South Africa"}}},{id:"141386",title:"Prof.",name:"Jesús",middleName:null,surname:"López-Rodríguez",slug:"jesus-lopez-rodriguez",fullName:"Jesús López-Rodríguez",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRBNIQA4/Profile_Picture_2022-03-21T08:24:16.jpg",institutionString:null,institution:{name:"University of A Coruña",institutionURL:null,country:{name:"Spain"}}},{id:"208657",title:"Dr.",name:"Mara",middleName:null,surname:"Del Baldo",slug:"mara-del-baldo",fullName:"Mara Del Baldo",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRLMUQA4/Profile_Picture_2022-05-18T08:19:24.png",institutionString:"University of Urbino Carlo Bo",institution:null}]},onlineFirstChapters:{paginationCount:17,paginationItems:[{id:"82184",title:"Biological Sensing Using Infrared SPR Devices Based on ZnO",doi:"10.5772/intechopen.104562",signatures:"Hiroaki Matsui",slug:"biological-sensing-using-infrared-spr-devices-based-on-zno",totalDownloads:3,totalCrossrefCites:0,totalDimensionsCites:0,authors:[{name:"Hiroaki",surname:"Matsui"}],book:{title:"Biosignal Processing",coverURL:"https://cdn.intechopen.com/books/images_new/11153.jpg",subseries:{id:"7",title:"Bioinformatics and Medical Informatics"}}},{id:"82122",title:"Recent Advances in Biosensing in Tissue Engineering and Regenerative Medicine",doi:"10.5772/intechopen.104922",signatures:"Alma T. Banigo, Chigozie A. Nnadiekwe and Emmanuel M. Beasi",slug:"recent-advances-in-biosensing-in-tissue-engineering-and-regenerative-medicine",totalDownloads:12,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Biosignal Processing",coverURL:"https://cdn.intechopen.com/books/images_new/11153.jpg",subseries:{id:"7",title:"Bioinformatics and Medical Informatics"}}},{id:"82080",title:"The Clinical Usefulness of Prostate Cancer Biomarkers: Current and Future Directions",doi:"10.5772/intechopen.103172",signatures:"Donovan McGrowder, Lennox Anderson-Jackson, Lowell Dilworth, Shada Mohansingh, Melisa Anderson Cross, Sophia Bryan, Fabian Miller, Cameil Wilson-Clarke, Chukwuemeka Nwokocha, Ruby Alexander-Lindo and Shelly McFarlane",slug:"the-clinical-usefulness-of-prostate-cancer-biomarkers-current-and-future-directions",totalDownloads:14,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Cancer Bioinformatics",coverURL:"https://cdn.intechopen.com/books/images_new/10661.jpg",subseries:{id:"7",title:"Bioinformatics and Medical Informatics"}}},{id:"82005",title:"Non-Invasive Approach for Glucose Detection in Urine Quality using Its Image Analysis",doi:"10.5772/intechopen.104791",signatures:"Anton Yudhana, Liya Yusrina Sabila, Arsyad Cahya Subrata, Hendriana Helda Pratama and Muhammad Syahrul Akbar",slug:"non-invasive-approach-for-glucose-detection-in-urine-quality-using-its-image-analysis",totalDownloads:4,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Biosignal Processing",coverURL:"https://cdn.intechopen.com/books/images_new/11153.jpg",subseries:{id:"7",title:"Bioinformatics and Medical Informatics"}}},{id:"81751",title:"NanoBioSensors: From Electrochemical Sensors Improvement to Theranostic Applications",doi:"10.5772/intechopen.102552",signatures:"Anielle C.A. Silva, Eliete A. Alvin, Lais S. de Jesus, Caio C.L. de França, Marílya P.G. da Silva, Samaysa L. Lins, Diógenes Meneses, Marcela R. Lemes, Rhanoica O. Guerra, Marcos V. da Silva, Carlo J.F. de Oliveira, Virmondes Rodrigues Junior, Renata M. Etchebehere, Fabiane C. de Abreu, Bruno G. Lucca, Sanívia A.L. Pereira, Rodrigo C. Rosa and Noelio O. Dantas",slug:"nanobiosensors-from-electrochemical-sensors-improvement-to-theranostic-applications",totalDownloads:12,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Biosignal Processing",coverURL:"https://cdn.intechopen.com/books/images_new/11153.jpg",subseries:{id:"7",title:"Bioinformatics and Medical Informatics"}}},{id:"81678",title:"Developmental Studies on Practical Enzymatic Phosphate Ion Biosensors and Microbial BOD Biosensors, and New Insights into the Future Perspectives of These Biosensor Fields",doi:"10.5772/intechopen.104377",signatures:"Hideaki Nakamura",slug:"developmental-studies-on-practical-enzymatic-phosphate-ion-biosensors-and-microbial-bod-biosensors-a",totalDownloads:5,totalCrossrefCites:0,totalDimensionsCites:0,authors:[{name:"Hideaki",surname:"Nakamura"}],book:{title:"Biosignal Processing",coverURL:"https://cdn.intechopen.com/books/images_new/11153.jpg",subseries:{id:"7",title:"Bioinformatics and Medical Informatics"}}},{id:"81412",title:"Mathematical Morphology and the Heart Signals",doi:"10.5772/intechopen.104113",signatures:"Taouli Sidi Ahmed",slug:"mathematical-morphology-and-the-heart-signals",totalDownloads:23,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Biosignal Processing",coverURL:"https://cdn.intechopen.com/books/images_new/11153.jpg",subseries:{id:"7",title:"Bioinformatics and Medical Informatics"}}},{id:"81360",title:"Deep Learning Algorithms for Efficient Analysis of ECG Signals to Detect Heart Disorders",doi:"10.5772/intechopen.103075",signatures:"Sumagna Dey, Rohan Pal and Saptarshi Biswas",slug:"deep-learning-algorithms-for-efficient-analysis-of-ecg-signals-to-detect-heart-disorders",totalDownloads:51,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Biosignal Processing",coverURL:"https://cdn.intechopen.com/books/images_new/11153.jpg",subseries:{id:"7",title:"Bioinformatics and Medical Informatics"}}},{id:"81068",title:"Characteristic Profiles of Heart Rate Variability in Depression and Anxiety",doi:"10.5772/intechopen.104205",signatures:"Toshikazu Shinba",slug:"characteristic-profiles-of-heart-rate-variability-in-depression-and-anxiety",totalDownloads:22,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Biosignal Processing",coverURL:"https://cdn.intechopen.com/books/images_new/11153.jpg",subseries:{id:"7",title:"Bioinformatics and Medical Informatics"}}},{id:"80691",title:"Applications of Quantum Mechanics, Laws of Classical Physics, and Differential Calculus to Evaluate Source Localization According to the Electroencephalogram",doi:"10.5772/intechopen.102831",signatures:"Kristin S. Williams",slug:"applications-of-quantum-mechanics-laws-of-classical-physics-and-differential-calculus-to-evaluate-so",totalDownloads:16,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Biosignal Processing",coverURL:"https://cdn.intechopen.com/books/images_new/11153.jpg",subseries:{id:"7",title:"Bioinformatics and Medical Informatics"}}},{id:"80643",title:"EEG Authentication System Using Fuzzy Vault Scheme",doi:"10.5772/intechopen.102699",signatures:"Fatima M. Baqer and Salah Albermany",slug:"eeg-authentication-system-using-fuzzy-vault-scheme",totalDownloads:45,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Biosignal Processing",coverURL:"https://cdn.intechopen.com/books/images_new/11153.jpg",subseries:{id:"7",title:"Bioinformatics and Medical Informatics"}}},{id:"80529",title:"Effective EEG Artifact Removal from EEG Signal",doi:"10.5772/intechopen.102698",signatures:"Vandana Roy",slug:"effective-eeg-artifact-removal-from-eeg-signal",totalDownloads:75,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Biosignal Processing",coverURL:"https://cdn.intechopen.com/books/images_new/11153.jpg",subseries:{id:"7",title:"Bioinformatics and Medical Informatics"}}},{id:"80505",title:"Soft Tissue Image Reconstruction Using Diffuse Optical Tomography",doi:"10.5772/intechopen.102463",signatures:"Umamaheswari K, Shrichandran G.V. and Jebaderwin D.",slug:"soft-tissue-image-reconstruction-using-diffuse-optical-tomography",totalDownloads:54,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Biosignal Processing",coverURL:"https://cdn.intechopen.com/books/images_new/11153.jpg",subseries:{id:"7",title:"Bioinformatics and Medical Informatics"}}},{id:"79881",title:"Control of Cytoskeletal Dynamics in Cancer through a Combination of Cytoskeletal Components",doi:"10.5772/intechopen.101624",signatures:"Ban Hussein Alwash, Rawan Asaad Jaber Al-Rubaye, Mustafa Mohammad Alaaraj and Anwar Yahya Ebrahim",slug:"control-of-cytoskeletal-dynamics-in-cancer-through-a-combination-of-cytoskeletal-components",totalDownloads:117,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Cancer Bioinformatics",coverURL:"https://cdn.intechopen.com/books/images_new/10661.jpg",subseries:{id:"7",title:"Bioinformatics and Medical Informatics"}}},{id:"79580",title:"Dotting the “i” of Interoperability in FAIR Cancer-Registry Data Sets",doi:"10.5772/intechopen.101330",signatures:"Nicholas Nicholson, Francesco Giusti, Luciana Neamtiu, Giorgia Randi, Tadeusz Dyba, Manola Bettio, Raquel Negrao Carvalho, Nadya Dimitrova, Manuela Flego and Carmen Martos",slug:"dotting-the-i-of-interoperability-in-fair-cancer-registry-data-sets",totalDownloads:114,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Cancer Bioinformatics",coverURL:"https://cdn.intechopen.com/books/images_new/10661.jpg",subseries:{id:"7",title:"Bioinformatics and Medical Informatics"}}},{id:"79550",title:"Urologic Cancer Molecular Biology",doi:"10.5772/intechopen.101381",signatures:"Pavel Onofrei, Viorel Dragoș Radu, Alina-Alexandra Onofrei, Stoica Laura, Doinita Temelie-Olinici, Ana-Emanuela Botez, Vasile Bogdan Grecu and Elena Carmen Cotrutz",slug:"urologic-cancer-molecular-biology",totalDownloads:104,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Cancer Bioinformatics",coverURL:"https://cdn.intechopen.com/books/images_new/10661.jpg",subseries:{id:"7",title:"Bioinformatics and Medical Informatics"}}}]},publishedBooks:{paginationCount:12,paginationItems:[{type:"book",id:"11332",title:"Essential Oils",subtitle:"Advances in Extractions and Biological Applications",coverURL:"https://cdn.intechopen.com/books/images_new/11332.jpg",slug:"essential-oils-advances-in-extractions-and-biological-applications",publishedDate:"June 23rd 2022",editedByType:"Edited by",bookSignature:"Mozaniel Santana de Oliveira and Eloisa Helena de Aguiar Andrade",hash:"742e6cae3a35686f975edc8d7f9afa94",volumeInSeries:32,fullTitle:"Essential Oils - Advances in Extractions and Biological Applications",editors:[{id:"195290",title:"Ph.D.",name:"Mozaniel",middleName:null,surname:"Santana De Oliveira",slug:"mozaniel-santana-de-oliveira",fullName:"Mozaniel Santana De Oliveira",profilePictureURL:"https://mts.intechopen.com/storage/users/195290/images/system/195290.png",institutionString:"Museu Paraense Emílio Goeldi",institution:{name:"Museu Paraense Emílio Goeldi",institutionURL:null,country:{name:"Brazil"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"10841",title:"Hydrolases",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/10841.jpg",slug:"hydrolases",publishedDate:"June 15th 2022",editedByType:"Edited by",bookSignature:"Sajjad Haider, Adnan Haider and Angel Catalá",hash:"4e868cde273d65a7ff54b1817d640629",volumeInSeries:29,fullTitle:"Hydrolases",editors:[{id:"110708",title:"Dr.",name:"Sajjad",middleName:null,surname:"Haider",slug:"sajjad-haider",fullName:"Sajjad Haider",profilePictureURL:"https://mts.intechopen.com/storage/users/110708/images/system/110708.png",institutionString:"King Saud University",institution:{name:"King Saud University",institutionURL:null,country:{name:"Saudi Arabia"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"10799",title:"Phenolic Compounds",subtitle:"Chemistry, Synthesis, Diversity, Non-Conventional Industrial, Pharmaceutical and Therapeutic Applications",coverURL:"https://cdn.intechopen.com/books/images_new/10799.jpg",slug:"phenolic-compounds-chemistry-synthesis-diversity-non-conventional-industrial-pharmaceutical-and-therapeutic-applications",publishedDate:"February 23rd 2022",editedByType:"Edited by",bookSignature:"Farid A. Badria",hash:"339199f254d2987ef3167eef74fb8a38",volumeInSeries:26,fullTitle:"Phenolic Compounds - Chemistry, Synthesis, Diversity, Non-Conventional Industrial, Pharmaceutical and Therapeutic Applications",editors:[{id:"41865",title:"Prof.",name:"Farid A.",middleName:null,surname:"Badria",slug:"farid-a.-badria",fullName:"Farid A. Badria",profilePictureURL:"https://mts.intechopen.com/storage/users/41865/images/system/41865.jpg",institutionString:"Mansoura University",institution:{name:"Mansoura University",institutionURL:null,country:{name:"Egypt"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"9753",title:"Terpenes and Terpenoids",subtitle:"Recent Advances",coverURL:"https://cdn.intechopen.com/books/images_new/9753.jpg",slug:"terpenes-and-terpenoids-recent-advances",publishedDate:"July 28th 2021",editedByType:"Edited by",bookSignature:"Shagufta Perveen and Areej Mohammad Al-Taweel",hash:"575689df13c78bf0e6c1be40804cd010",volumeInSeries:21,fullTitle:"Terpenes and Terpenoids - Recent Advances",editors:[{id:"192992",title:"Prof.",name:"Shagufta",middleName:null,surname:"Perveen",slug:"shagufta-perveen",fullName:"Shagufta Perveen",profilePictureURL:"https://mts.intechopen.com/storage/users/192992/images/system/192992.png",institutionString:"King Saud University",institution:{name:"King Saud University",institutionURL:null,country:{name:"Saudi Arabia"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"9731",title:"Oxidoreductase",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/9731.jpg",slug:"oxidoreductase",publishedDate:"February 17th 2021",editedByType:"Edited by",bookSignature:"Mahmoud Ahmed Mansour",hash:"852e6f862c85fc3adecdbaf822e64e6e",volumeInSeries:19,fullTitle:"Oxidoreductase",editors:[{id:"224662",title:"Prof.",name:"Mahmoud Ahmed",middleName:null,surname:"Mansour",slug:"mahmoud-ahmed-mansour",fullName:"Mahmoud Ahmed Mansour",profilePictureURL:"https://mts.intechopen.com/storage/users/224662/images/system/224662.jpg",institutionString:"King Saud bin Abdulaziz University for Health Sciences",institution:{name:"King Saud bin Abdulaziz University for Health Sciences",institutionURL:null,country:{name:"Saudi Arabia"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"8094",title:"Aflatoxin B1 Occurrence, Detection and Toxicological Effects",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/8094.jpg",slug:"aflatoxin-b1-occurrence-detection-and-toxicological-effects",publishedDate:"June 3rd 2020",editedByType:"Edited by",bookSignature:"Xi-Dai Long",hash:"44f4ad52d8a8cbb22ef3d505d6b18027",volumeInSeries:14,fullTitle:"Aflatoxin B1 Occurrence, Detection and Toxicological Effects",editors:[{id:"202142",title:"Prof.",name:"Xi-Dai",middleName:null,surname:"Long",slug:"xi-dai-long",fullName:"Xi-Dai Long",profilePictureURL:"https://mts.intechopen.com/storage/users/202142/images/system/202142.jpeg",institutionString:"Youjiang Medical University for Nationalities",institution:null}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"8004",title:"Nitrogen Fixation",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/8004.jpg",slug:"nitrogen-fixation",publishedDate:"April 8th 2020",editedByType:"Edited by",bookSignature:"Everlon Cid Rigobelo and Ademar Pereira Serra",hash:"02f39c8365ba155d1c520184c2f26976",volumeInSeries:11,fullTitle:"Nitrogen Fixation",editors:[{id:"39553",title:"Prof.",name:"Everlon",middleName:"Cid",surname:"Rigobelo",slug:"everlon-rigobelo",fullName:"Everlon Rigobelo",profilePictureURL:"https://mts.intechopen.com/storage/users/39553/images/system/39553.jpg",institutionString:"São Paulo State University",institution:{name:"Sao Paulo State University",institutionURL:null,country:{name:"Brazil"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"8028",title:"Flavonoids",subtitle:"A Coloring Model for Cheering up Life",coverURL:"https://cdn.intechopen.com/books/images_new/8028.jpg",slug:"flavonoids-a-coloring-model-for-cheering-up-life",publishedDate:"March 11th 2020",editedByType:"Edited by",bookSignature:"Farid A. Badria and Anthony Ananga",hash:"6c33178a5c7d2b276d2c6af4255def64",volumeInSeries:10,fullTitle:"Flavonoids - A Coloring Model for Cheering up Life",editors:[{id:"41865",title:"Prof.",name:"Farid A.",middleName:null,surname:"Badria",slug:"farid-a.-badria",fullName:"Farid A. Badria",profilePictureURL:"https://mts.intechopen.com/storage/users/41865/images/system/41865.jpg",institutionString:"Mansoura University",institution:{name:"Mansoura University",institutionURL:null,country:{name:"Egypt"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"8170",title:"Chemical Properties of Starch",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/8170.jpg",slug:"chemical-properties-of-starch",publishedDate:"March 11th 2020",editedByType:"Edited by",bookSignature:"Martins Emeje",hash:"0aedfdb374631bb3a33870c4ed16559a",volumeInSeries:9,fullTitle:"Chemical Properties of Starch",editors:[{id:"94311",title:"Prof.",name:"Martins",middleName:"Ochubiojo",surname:"Emeje",slug:"martins-emeje",fullName:"Martins Emeje",profilePictureURL:"https://mts.intechopen.com/storage/users/94311/images/system/94311.jpeg",institutionString:"National Institute for Pharmaceutical Research and Development",institution:{name:"National Institute for Pharmaceutical Research and Development",institutionURL:null,country:{name:"Nigeria"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"8019",title:"Alginates",subtitle:"Recent Uses of This Natural Polymer",coverURL:"https://cdn.intechopen.com/books/images_new/8019.jpg",slug:"alginates-recent-uses-of-this-natural-polymer",publishedDate:"February 5th 2020",editedByType:"Edited by",bookSignature:"Leonel Pereira",hash:"61ea5c1aef462684a3b2215631b7dbf2",volumeInSeries:7,fullTitle:"Alginates - Recent Uses of This Natural Polymer",editors:[{id:"279788",title:"Dr.",name:"Leonel",middleName:null,surname:"Pereira",slug:"leonel-pereira",fullName:"Leonel Pereira",profilePictureURL:"https://mts.intechopen.com/storage/users/279788/images/system/279788.jpg",institutionString:"University of Coimbra",institution:{name:"University of Coimbra",institutionURL:null,country:{name:"Portugal"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"8504",title:"Pectins",subtitle:"Extraction, Purification, Characterization and Applications",coverURL:"https://cdn.intechopen.com/books/images_new/8504.jpg",slug:"pectins-extraction-purification-characterization-and-applications",publishedDate:"January 22nd 2020",editedByType:"Edited by",bookSignature:"Martin Masuelli",hash:"ff1acef627b277c575a10b3259dd331b",volumeInSeries:6,fullTitle:"Pectins - Extraction, Purification, Characterization and Applications",editors:[{id:"99994",title:"Dr.",name:"Martin",middleName:"Alberto",surname:"Masuelli",slug:"martin-masuelli",fullName:"Martin Masuelli",profilePictureURL:"https://mts.intechopen.com/storage/users/99994/images/system/99994.png",institutionString:"National University of San Luis",institution:{name:"National University of San Luis",institutionURL:null,country:{name:"Argentina"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"7953",title:"Bioluminescence",subtitle:"Analytical Applications and Basic Biology",coverURL:"https://cdn.intechopen.com/books/images_new/7953.jpg",slug:"bioluminescence-analytical-applications-and-basic-biology",publishedDate:"September 25th 2019",editedByType:"Edited by",bookSignature:"Hirobumi Suzuki",hash:"3a8efa00b71abea11bf01973dc589979",volumeInSeries:4,fullTitle:"Bioluminescence - Analytical Applications and Basic Biology",editors:[{id:"185746",title:"Dr.",name:"Hirobumi",middleName:null,surname:"Suzuki",slug:"hirobumi-suzuki",fullName:"Hirobumi Suzuki",profilePictureURL:"https://mts.intechopen.com/storage/users/185746/images/system/185746.png",institutionString:"Kogakuin University",institution:null}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null}]},testimonialsList:[{id:"8",text:"I work with IntechOpen for a number of reasons: their professionalism, their mission in support of Open Access publishing, and the quality of their peer-reviewed publications, but also because they believe in equality.",author:{id:"202192",name:"Catrin",surname:"Rutland",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/202192/images/system/202192.png",slug:"catrin-rutland",institution:{id:"134",name:"University of Nottingham",country:{id:null,name:"United Kingdom"}}}},{id:"27",text:"The opportunity to work with a prestigious publisher allows for the possibility to collaborate with more research groups interested in animal nutrition, leading to the development of new feeding strategies and food valuation while being more sustainable with the environment, allowing more readers to learn about the subject.",author:{id:"175967",name:"Manuel",surname:"Gonzalez Ronquillo",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/175967/images/system/175967.png",slug:"manuel-gonzalez-ronquillo",institution:{id:"6221",name:"Universidad Autónoma del Estado de México",country:{id:null,name:"Mexico"}}}},{id:"18",text:"It was great publishing with IntechOpen, the process was straightforward and I had support all along.",author:{id:"71579",name:"Berend",surname:"Olivier",institutionString:"Utrecht University",profilePictureURL:"https://mts.intechopen.com/storage/users/71579/images/system/71579.png",slug:"berend-olivier",institution:{id:"253",name:"Utrecht University",country:{id:null,name:"Netherlands"}}}}]},submityourwork:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:9,numberOfPublishedChapters:89,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:103,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:31,numberOfPublishedChapters:314,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:11,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:11,numberOfPublishedChapters:141,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:8,numberOfPublishedChapters:129,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!0},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:113,numberOfOpenTopics:3,numberOfUpcomingTopics:1,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:11,numberOfPublishedChapters:105,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:16,numberOfOpenTopics:2,numberOfUpcomingTopics:1,issn:"2753-894X",doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:4,numberOfOpenTopics:1,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!0},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:0,numberOfPublishedChapters:14,numberOfOpenTopics:5,numberOfUpcomingTopics:0,issn:null,doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],subseriesList:[],annualVolumeBook:{},thematicCollection:[],selectedSeries:null,selectedSubseries:null},seriesLanding:{item:{id:"11",title:"Biochemistry",doi:"10.5772/intechopen.72877",issn:"2632-0983",scope:"Biochemistry, the study of chemical transformations occurring within living organisms, impacts all areas of life sciences, from molecular crystallography and genetics to ecology, medicine, and population biology. Biochemistry examines macromolecules - proteins, nucleic acids, carbohydrates, and lipids – and their building blocks, structures, functions, and interactions. Much of biochemistry is devoted to enzymes, proteins that catalyze chemical reactions, enzyme structures, mechanisms of action and their roles within cells. Biochemistry also studies small signaling molecules, coenzymes, inhibitors, vitamins, and hormones, which play roles in life processes. Biochemical experimentation, besides coopting classical chemistry methods, e.g., chromatography, adopted new techniques, e.g., X-ray diffraction, electron microscopy, NMR, radioisotopes, and developed sophisticated microbial genetic tools, e.g., auxotroph mutants and their revertants, fermentation, etc. More recently, biochemistry embraced the ‘big data’ omics systems. Initial biochemical studies have been exclusively analytic: dissecting, purifying, and examining individual components of a biological system; in the apt words of Efraim Racker (1913 –1991), “Don’t waste clean thinking on dirty enzymes.” Today, however, biochemistry is becoming more agglomerative and comprehensive, setting out to integrate and describe entirely particular biological systems. The ‘big data’ metabolomics can define the complement of small molecules, e.g., in a soil or biofilm sample; proteomics can distinguish all the comprising proteins, e.g., serum; metagenomics can identify all the genes in a complex environment, e.g., the bovine rumen. This Biochemistry Series will address the current research on biomolecules and the emerging trends with great promise.",coverUrl:"https://cdn.intechopen.com/series/covers/11.jpg",latestPublicationDate:"June 24th, 2022",hasOnlineFirst:!0,numberOfOpenTopics:4,numberOfPublishedChapters:314,numberOfPublishedBooks:31,editor:{id:"31610",title:"Dr.",name:"Miroslav",middleName:null,surname:"Blumenberg",fullName:"Miroslav Blumenberg",profilePictureURL:"https://mts.intechopen.com/storage/users/31610/images/system/31610.jpg",biography:"Miroslav Blumenberg, Ph.D., was born in Subotica and received his BSc in Belgrade, Yugoslavia. He completed his Ph.D. at MIT in Organic Chemistry; he followed up his Ph.D. with two postdoctoral study periods at Stanford University. Since 1983, he has been a faculty member of the RO Perelman Department of Dermatology, NYU School of Medicine, where he is codirector of a training grant in cutaneous biology. Dr. Blumenberg’s research is focused on the epidermis, expression of keratin genes, transcription profiling, keratinocyte differentiation, inflammatory diseases and cancers, and most recently the effects of the microbiome on the skin. He has published more than 100 peer-reviewed research articles and graduated numerous Ph.D. and postdoctoral students.",institutionString:null,institution:{name:"New York University Langone Medical Center",institutionURL:null,country:{name:"United States of America"}}},subseries:[{id:"14",title:"Cell and Molecular Biology",keywords:"Omics (Transcriptomics; Proteomics; Metabolomics), Molecular Biology, Cell Biology, Signal Transduction and Regulation, Cell Growth and Differentiation, Apoptosis, Necroptosis, Ferroptosis, Autophagy, Cell Cycle, Macromolecules and Complexes, Gene Expression",scope:"The Cell and Molecular Biology topic within the IntechOpen Biochemistry Series aims to rapidly publish contributions on all aspects of cell and molecular biology, including aspects related to biochemical and genetic research (not only in humans but all living beings). We encourage the submission of manuscripts that provide novel and mechanistic insights that report significant advances in the fields. Topics include, but are not limited to: Advanced techniques of cellular and molecular biology (Molecular methodologies, imaging techniques, and bioinformatics); Biological activities at the molecular level; Biological processes of cell functions, cell division, senescence, maintenance, and cell death; Biomolecules interactions; Cancer; Cell biology; Chemical biology; Computational biology; Cytochemistry; Developmental biology; Disease mechanisms and therapeutics; DNA, and RNA metabolism; Gene functions, genetics, and genomics; Genetics; Immunology; Medical microbiology; Molecular biology; Molecular genetics; Molecular processes of cell and organelle dynamics; Neuroscience; Protein biosynthesis, degradation, and functions; Regulation of molecular interactions in a cell; Signalling networks and system biology; Structural biology; Virology and microbiology.",annualVolume:11410,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/14.jpg",editor:{id:"165627",title:"Dr.",name:"Rosa María",middleName:null,surname:"Martínez-Espinosa",fullName:"Rosa María Martínez-Espinosa",profilePictureURL:"https://mts.intechopen.com/storage/users/165627/images/system/165627.jpeg",institutionString:null,institution:{name:"University of Alicante",institutionURL:null,country:{name:"Spain"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"79367",title:"Dr.",name:"Ana Isabel",middleName:null,surname:"Flores",fullName:"Ana Isabel Flores",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRpIOQA0/Profile_Picture_1632418099564",institutionString:null,institution:{name:"Hospital Universitario 12 De Octubre",institutionURL:null,country:{name:"Spain"}}},{id:"328234",title:"Ph.D.",name:"Christian",middleName:null,surname:"Palavecino",fullName:"Christian Palavecino",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000030DhEhQAK/Profile_Picture_1628835318625",institutionString:null,institution:{name:"Central University of Chile",institutionURL:null,country:{name:"Chile"}}},{id:"186585",title:"Dr.",name:"Francisco Javier",middleName:null,surname:"Martin-Romero",fullName:"Francisco Javier Martin-Romero",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSB3HQAW/Profile_Picture_1631258137641",institutionString:null,institution:{name:"University of Extremadura",institutionURL:null,country:{name:"Spain"}}}]},{id:"15",title:"Chemical Biology",keywords:"Phenolic Compounds, Essential Oils, Modification of Biomolecules, Glycobiology, Combinatorial Chemistry, Therapeutic peptides, Enzyme Inhibitors",scope:"Chemical biology spans the fields of chemistry and biology involving the application of biological and chemical molecules and techniques. In recent years, the application of chemistry to biological molecules has gained significant interest in medicinal and pharmacological studies. This topic will be devoted to understanding the interplay between biomolecules and chemical compounds, their structure and function, and their potential applications in related fields. Being a part of the biochemistry discipline, the ideas and concepts that have emerged from Chemical Biology have affected other related areas. This topic will closely deal with all emerging trends in this discipline.",annualVolume:11411,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/15.jpg",editor:{id:"441442",title:"Dr.",name:"Şükrü",middleName:null,surname:"Beydemir",fullName:"Şükrü Beydemir",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00003GsUoIQAV/Profile_Picture_1634557147521",institutionString:null,institution:{name:"Anadolu University",institutionURL:null,country:{name:"Turkey"}}},editorTwo:{id:"13652",title:"Prof.",name:"Deniz",middleName:null,surname:"Ekinci",fullName:"Deniz Ekinci",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYLT1QAO/Profile_Picture_1634557223079",institutionString:null,institution:{name:"Ondokuz Mayıs University",institutionURL:null,country:{name:"Turkey"}}},editorThree:null,editorialBoard:[{id:"241413",title:"Dr.",name:"Azhar",middleName:null,surname:"Rasul",fullName:"Azhar Rasul",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRT1oQAG/Profile_Picture_1635251978933",institutionString:null,institution:{name:"Government College University, Faisalabad",institutionURL:null,country:{name:"Pakistan"}}},{id:"178316",title:"Ph.D.",name:"Sergey",middleName:null,surname:"Sedykh",fullName:"Sergey Sedykh",profilePictureURL:"https://mts.intechopen.com/storage/users/178316/images/system/178316.jfif",institutionString:null,institution:{name:"Novosibirsk State University",institutionURL:null,country:{name:"Russia"}}}]},{id:"17",title:"Metabolism",keywords:"Biomolecules Metabolism, Energy Metabolism, Metabolic Pathways, Key Metabolic Enzymes, Metabolic Adaptation",scope:"Metabolism is frequently defined in biochemistry textbooks as the overall process that allows living systems to acquire and use the free energy they need for their vital functions or the chemical processes that occur within a living organism to maintain life. Behind these definitions are hidden all the aspects of normal and pathological functioning of all processes that the topic ‘Metabolism’ will cover within the Biochemistry Series. Thus all studies on metabolism will be considered for publication.",annualVolume:11413,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/17.jpg",editor:{id:"138626",title:"Dr.",name:"Yannis",middleName:null,surname:"Karamanos",fullName:"Yannis Karamanos",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002g6Jv2QAE/Profile_Picture_1629356660984",institutionString:null,institution:{name:"Artois University",institutionURL:null,country:{name:"France"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"243049",title:"Dr.",name:"Anca",middleName:null,surname:"Pantea Stoian",fullName:"Anca Pantea Stoian",profilePictureURL:"https://mts.intechopen.com/storage/users/243049/images/system/243049.jpg",institutionString:null,institution:{name:"Carol Davila University of Medicine and Pharmacy",institutionURL:null,country:{name:"Romania"}}},{id:"203824",title:"Dr.",name:"Attilio",middleName:null,surname:"Rigotti",fullName:"Attilio Rigotti",profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institutionString:null,institution:{name:"Pontifical Catholic University of Chile",institutionURL:null,country:{name:"Chile"}}},{id:"300470",title:"Dr.",name:"Yanfei (Jacob)",middleName:null,surname:"Qi",fullName:"Yanfei (Jacob) Qi",profilePictureURL:"https://mts.intechopen.com/storage/users/300470/images/system/300470.jpg",institutionString:null,institution:{name:"Centenary Institute of Cancer Medicine and Cell Biology",institutionURL:null,country:{name:"Australia"}}}]},{id:"18",title:"Proteomics",keywords:"Mono- and Two-Dimensional Gel Electrophoresis (1-and 2-DE), Liquid Chromatography (LC), Mass Spectrometry/Tandem Mass Spectrometry (MS; MS/MS), Proteins",scope:"With the recognition that the human genome cannot provide answers to the etiology of a disorder, changes in the proteins expressed by a genome became a focus in research. Thus proteomics, an area of research that detects all protein forms expressed in an organism, including splice isoforms and post-translational modifications, is more suitable than genomics for a comprehensive understanding of the biochemical processes that govern life. The most common proteomics applications are currently in the clinical field for the identification, in a variety of biological matrices, of biomarkers for diagnosis and therapeutic intervention of disorders. From the comparison of proteomic profiles of control and disease or different physiological states, which may emerge, changes in protein expression can provide new insights into the roles played by some proteins in human pathologies. Understanding how proteins function and interact with each other is another goal of proteomics that makes this approach even more intriguing. Specialized technology and expertise are required to assess the proteome of any biological sample. Currently, proteomics relies mainly on mass spectrometry (MS) combined with electrophoretic (1 or 2-DE-MS) and/or chromatographic techniques (LC-MS/MS). MS is an excellent tool that has gained popularity in proteomics because of its ability to gather a complex body of information such as cataloging protein expression, identifying protein modification sites, and defining protein interactions. The Proteomics topic aims to attract contributions on all aspects of MS-based proteomics that, by pushing the boundaries of MS capabilities, may address biological problems that have not been resolved yet.",annualVolume:11414,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/18.jpg",editor:{id:"200689",title:"Prof.",name:"Paolo",middleName:null,surname:"Iadarola",fullName:"Paolo Iadarola",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSCl8QAG/Profile_Picture_1623568118342",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorTwo:{id:"201414",title:"Dr.",name:"Simona",middleName:null,surname:"Viglio",fullName:"Simona Viglio",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRKDHQA4/Profile_Picture_1630402531487",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorThree:null,editorialBoard:[{id:"72288",title:"Dr.",name:"Arli Aditya",middleName:null,surname:"Parikesit",fullName:"Arli Aditya Parikesit",profilePictureURL:"https://mts.intechopen.com/storage/users/72288/images/system/72288.jpg",institutionString:null,institution:{name:"Indonesia International Institute for Life Sciences",institutionURL:null,country:{name:"Indonesia"}}},{id:"40928",title:"Dr.",name:"Cesar",middleName:null,surname:"Lopez-Camarillo",fullName:"Cesar Lopez-Camarillo",profilePictureURL:"https://mts.intechopen.com/storage/users/40928/images/3884_n.png",institutionString:null,institution:{name:"Universidad Autónoma de la Ciudad de México",institutionURL:null,country:{name:"Mexico"}}},{id:"81926",title:"Dr.",name:"Shymaa",middleName:null,surname:"Enany",fullName:"Shymaa Enany",profilePictureURL:"https://mts.intechopen.com/storage/users/81926/images/system/81926.png",institutionString:"Suez Canal University",institution:{name:"Suez Canal University",institutionURL:null,country:{name:"Egypt"}}}]}]}},libraryRecommendation:{success:null,errors:{},institutions:[]},route:{name:"profile.detail",path:"/profiles/178886",hash:"",query:{},params:{id:"178886"},fullPath:"/profiles/178886",meta:{},from:{name:null,path:"/",hash:"",query:{},params:{},fullPath:"/",meta:{}}}},function(){var e;(e=document.currentScript||document.scripts[document.scripts.length-1]).parentNode.removeChild(e)}()