Ana Maria Fernandez-Escamilla

Ana-María Fernández-Escamilla is a senior researcher at Spanish National Research Council. In 2001, she received her PhD in Biophysical Chemistry at the University of Granada, Spain. She developed her career in prestigious Spanish and international research centers as European Molecular Biology Laboratory (Germany), funded by National and European competing grants. She participated in the development and testing of the computer algorithm “TANGO”, designed to predict protein aggregation propensity. Currently, she develops as PI two R&D projects funded by public bodies and one biotech-company research contract. In 2014, she got positive assessment of research excellence by the Spanish National Evaluation and Foresight Agency. Her scientific research is focused on protein engineering combining theoretical and experimental approaches for biochemical, biophysical, and structural characterization of macromolecules.

1books edited

Latest work with IntechOpen by Ana Maria Fernandez-Escamilla

Amyloid protein aggregates are involved in ''protein-misfolding diseases'' of enormous social and economic impact, still with no effective therapies. The most prevalent amyloid pathologies are related to neurodegenerative diseases, but amyloidosis also affects other organs. The majority of the studies includes serious health connotations on amyloids. However, not all amyloid fibers play a detrimental role in host. An increasing number of studies shows an important beneficial role as ''functional amyloids''. This book opens an exciting door to provide up-to-date information about the function and the mechanisms of the amyloid formation process from the structural, biophysical, biomedical, and nanotechnological perspective, combining the new findings on toxic and functional amyloids studies using theoretical and experimental approaches to fight against amyloid-based diseases.

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Exploring New Findings on Amyloidosis

Edited by Ana Maria Fernandez-Escamilla