Ana Cristina Andreazza

University of Toronto Canada

Ana Cristina Andreazza obtained her PhD in Biochemistry from Federal University of Rio Grande do Sul, RS, Brazil in May 2008.  Her research interests include the role of biochemical pathways in the pathophysiology of mood disorder, particularly those involving oxidative stress and mitochondrial dysfunction. Specifically, she is interested in exploring the possible connections between molecular mechanisms that lead to synaptic alterations and those which may be potential avenues for therapy. For example, many proteins are targets for oxidative damage in BD, which include dopamine, synaptophysin, cytochrome C, in addition to mitochondrial proteins. Given the clear evidence from multiple sources of increased oxidative stress in BD, Dr. Andreazza\'s next step is to identify the protein targets for oxidation in BD. Dr. Andreazza has published several research articles in peer reviewed journals and has presented her work at several national and international scientific conferences.  Currently, Dr. Andreazza is an Assistant Professor at Department of Pharmacology at the University of Toronto and is cross-appointed as an Independent Scientist at Centre for Addiction and Mental Health in Toronto, Canada, and an Assistant Professor at Department of Psychiatry at the University of Toronto.

Ana Cristina Andreazza

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Latest work with IntechOpen by Ana Cristina Andreazza

The increased exposure to toxins, toxicants and novel drugs has promoted toxicology to become one of the most important areas of research with emerging innovative toxicity testing protocols, techniques, and regulation being placed. Since the bioactivation of many toxins and toxicants and its consequences on human health are not clearly known, this book offers a quick overview of cellular toxicology through the cell, drug and environmental toxicity. This book does not strive to be comprehensive but instead offers a quick overview of principle aspects of toxins and toxicants in order to familiarize the key principles of toxicology. The book is divided into three main sections,; the first one discusses the role of mitochondrial dysfunction, oxidative stress and mitochondrial drug development. The second and third sections bring light to forensic toxicology and drug poisoning followed by environmental toxicity.

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