Part of the book: Selected Topics in Applications of Quantum Mechanics
Part of the book: Advances in Osteoporosis
The research described in this study aimed at developing microemulsions for dermal application using avocado oil. Due to its composition, avocado oil helps maintaining the barrier function of the skin. It has a nutritional effect on the skin, and it reduces the intensity of the process of skin peeling. Various surfactant:cosurfactant systems were tested in the conducted studies. There were no significant differences between the diagrams generated by Tween 20 and the surfactant:cosurfactant system, Tween 20:PEG400, at a ratio of 1:1. Six formulations were selected from the dilution line 7 of the ternary phase diagrams obtained by using as a surfactant Tween 20 and Tween 20:PEG 400, respectively. The formulations were characterized by determining physicochemical properties specific. In the next phase of study, these six formulations were used as a vehicle for incorporating erythromycin in order to develop erythromicyn incorporated formulations for topical administration. The quality control of microemulsions with erythromycin was performed by evaluating the physical chemical, organoleptic and sensorial properties. Microemulsions were pharmacotechnically characterized by assessing the in vitro and ex vivo release kinetics of erythromycin.
Part of the book: Properties and Uses of Microemulsions