Characteristics of circumcised men aged 10–64 years in Botswana (2008 and 2013).
\r\n\tAtherosclerosis is a systemic disease. Some 60% of patients with peripheral artery disease will have ischaemic heart disease, and 30% have cerebrovascular disease. Within five years of diagnosis, 10-15% of patients with intermittent claudication will die from cardiovascular disease. Therefore, management begins with the identification and modification of risk factors that are common to peripheral artery disease, heart disease, and stroke. Treatment goals include reducing cardiovascular risk and improving functional capacity. Revascularization is indicated for persistent symptoms.
\r\n\tThe main objective of the book is to deal with peripheral arterial disease in the most diverse aspects. Addressing issues such as pathophysiology, signs and symptoms, clinical aspects, treatment, and prognosis.
\r\n\t
Male circumcision is not a new practice in Africa. It has been practiced for thousands of years as a ritual and a rite of passage to manhood [1, 2]. Similarly, in Botswana, male circumcision has been practiced as far as 1875, marked by an initiation ceremony into manhood called “bogwera” [3]. During the
In 1985, Botswana had the first HIV/AIDS case. Ever since from that time, a series of response plans and programs have been devised to reduce HIV transmission. In the early 2000s, epidemiological studies observed a significant association between circumcision and low HIV/AIDS prevalence [7, 8, 9]. It was found that countries with high circumcision rates recorded the lowest HIV/AIDS prevalence rates, in West, East, and Southern Africa [1]. Most of the studies conducted in these regions found that circumcision reduced vulnerability to HIV [10, 11, 12]. In order to provide conclusive empirical evidence, three randomized clinical trials were conducted to assess the effects of safe male circumcision for the prevention of HIV infection through heterosexual contact in South Africa, Uganda, and Kenya [13, 14, 15]. These trials congruently showed that HIV transmission was reduced by over 60% among circumcised men.
Owing to the evidence of the protective effects of circumcision against HIV transmission, several studies were undertaken in Botswana. Initial studies assessed the acceptability of safe male circumcision (SMC) among men in Botswana [16]. Subsequently, a mathematical model was used to calculate the public health impact of large safe male circumcision for HIV prevention. It was found that male HIV prevalence reduced from 30 to 10% and female HIV prevalence was reduced from 40 to 20% [17]. In 2009 the government of Botswana through the Ministry of Health and Wellness adopted the voluntary safe male circumcision program [17]. A 5-year strategy was then developed, which aimed at reaching 80% circumcision coverage [17]. According to Dickson et al. [18], less than 20% of males in Botswana had access to male circumcision services in 2010. Although the SMC program has been running for about 10 years in Botswana, recent evidence indicates that the program has failed to achieve its intended coverage [3].
This chapter is therefore intended to provide the background and assess the patterns and correlates of safe male circumcision within the context of a high HIV/AIDS prevalence setting. The chapter starts by providing a brief background on male circumcision and the SMC program in Botswana. It goes on to assess the patterns and determinants of SMC since the introduction of the program in 2009. An understanding of the background, patterns, and correlates of safe male circumcision is essential for programming and assessment of the effectiveness of the program.
This chapter generally adopts a multifaceted approach that considers HIV/AIDS risk perception among circumcised men by assessing patterns of circumcision and factors associated with circumcision among men in Botswana. This is done with the assumption that circumcision can only be effective in the context where men consider its health benefits. Most public health studies have often used individual and social behavioral theories to explain why individuals are willing to undertake a certain action and why they behave the way they do [19, 20, 21, 22]. Individual behavior models focus on the role of individual characteristics in controlling individual behavior. Thus they focus on how individuals control their behaviors and make reasoned actions that impact those decisions [23]. On the other hand, social models include social pressures, peer influences, cultural expectations, economic factors affecting resource availability, legal and political structures, and political and religious ideologies that restrict individual’s options and the flow of information [23].
Among the various individual and social behavioral models, the theory of reasoned action (TRA) has been selected and used in this chapter to explain why men would or would not circumcise. The TRA was developed and revised numerous times by Ajzen and Fishbein [24, 25]. This theory proposes that behavioral intentions are a combined function of the attitude toward performing a particular behavior in a given situation and of the norms perceived to govern that behavior multiplied by the motivation to comply with those norms [26]. The assumption is that human beings are usually quite rational and make systematic use of the information available to them. People consider the implications of their actions before they decide to engage or not engage in a given behavior [25].
As circumcision is recommended for medical reasons (especially prevention of HIV acquisition), men who may choose circumcision must also believe that circumcision may reduce chances of HIV acquisition. This model was mainly chosen because, the constructs of this model are key in informing men’s decision to accept circumcision. The assumption of TRA is that most behaviors of social bearing are under voluntary control and that a person’s intention to perform or not do the behavior is the direct determinant of that action [25]. Consequently, men’s intention regarding SMC is determined by personal and social influences. One personal factor is the person’s evaluation of the outcome of circumcision, which can be either positive or negative.
Men who perceive that circumcision is necessary for reduction of HIV transmission may choose the procedure. Meanwhile men who believe otherwise may have negative evaluation of circumcision and may choose not to circumcise. Subjective norm is the other determinant of a person’s intention which is a person’s perception of the social pressures applied to perform the behavior [25]. As illustrated in Figure 1, an individual’s intentions and behaviors are influenced by certain background factors which include individual, social, and information factors.
Theory of reason action [
Data used in this chapter was derived from the two Botswana AIDS Impact Surveys (BAIS III and IV). BAIS III was conducted in 2008 before the implementation of SMC program, while BAIS IV was conducted in 2013 after the implementation of the SMC program. The main objectives of the BAIS were to provide information to assess whether programs are operating as intended; assess performance of intervention programs; assess whether people are changing their sexual behavior; establish the proportion of people in need of care due to HIV infection; establish the proportion of people who are at risk of HIV infection; assess the impact of the pandemic at household level; and provide information on issues related to the impact of HIV/AIDS on households and communities [27]. BAIS III and IV are the two surveys which have asked the same questions on male circumcision that can be used to assess the patterns and determinants of SMC in Botswana. A sample consisting of 6290 and 3787 men in ages 10–64 years who had successfully completed BAIS III and IV individual questionnaires, respectively, were selected and included for analyses. Respondents who did not complete the individual questionnaire were excluded from the present analysis.
The main variable of interest used in this paper is on “circumcision status.” This is based on the percentage of circumcised men between ages 10 and 64 years in the sample population. This variable is derived from self-reported responses to a question that sought to know whether the respondent was circumcised or not.
Sociodemographic variables such as age, sex, residence, education, and religion were used as control variables based on prior empirical research which has shown that conceptually these variables are associated with sexual risk behaviors [28, 29].
Analyses were conducted using SPSS version 25 program (IBM, SPSS, Chicago, IL, USA). In order to assess patterns of circumcision, adjusted prevalence ratios (APR) and their corresponding 95% confidence intervals were obtained using modified Poisson regression models. The associations between male circumcision and sociodemographic and behavioral factors were estimated for each of the surveys. In order to avoid cofounding effects between circumcision and covariates, sociodemographic variables were used as control variables. This ensured that the association between behavioral variables and circumcision becomes credible and discernible. In the adjusted analyses of sexual risk behaviors, sociodemographic characteristics were controlled for. In order to control for cluster effects, complex samples module in SPSS has been used since multistage probability sampling technique was used for both surveys.
Overall 785 (12.5%) and 956 (25.2%) men in the sample reported to have been circumcised in 2008 and 2013, respectively (Figure 2).
Percentage of circumcised men in Botswana (2008 and 2013). Source: Analyzed from Botswana AIDS Impact Surveys III and IV (2008 and 2013).
Table 1 shows the sociodemographic characteristics of circumcised men in Botswana (2008 and 2013). The proportion of men who were circumcised decreased with age for both surveys. For instance, in both surveys the highest proportions of circumcised men were found in ages 10–24 (25 and 28.7% for 2008 and 2013, respectively) and lowest in ages 55–64 years (8.3 and 9.8% for 2008 and 2013, respectively). A high proportion of circumcised men in both surveys was found among those with secondary education in 2008 and 2013 (53.1 and 49.5%, respectively), cities and towns (38.4 and 44.1%, respectively), never married individuals (47.8 and 53.7%), and Christians (64.4 and 81.4%, respectively).
Variables | 2008 BAIS | 2013 BAIS | ||
---|---|---|---|---|
Circumcised, % (n) | N | Circumcised, % (n) | N | |
Age | ||||
10–24 | 25.0 (184) | 2680 | 28.7 (274) | 1490 |
25–34 | 31.8 (234) | 1600 | 27.6 (264) | 954 |
35–44 | 21.8 (160) | 934 | 21.2 (203) | 680 |
45–54 | 13.1 (96) | 586 | 12.7 (121) | 399 |
55–64 | 8.3 (61) | 318 | 9.8 (94) | 264 |
Primary/less | 13.7 (78) | 841 | 18.8 (161) | 930 |
Secondary | 53.1 (302) | 2558 | 49.5 (423) | 1688 |
Tertiary/higher | 33.2 (189) | 894 | 31.7 (271) | 724 |
Cities and towns | 38.4 (282) | 1739 | 44.1 (422) | 1398 |
Urban villages | 31.0 (228) | 1901 | 25.9 (248) | 948 |
Rural villages | 30.6 (225) | 2478 | 29.9 (286) | 1441 |
Never married | 47.8 (351) | 3866 | 53.7 (513) | 2306 |
Married | 24.4 (179) | 874 | 21.9 (209) | 635 |
Cohabiting | 23.4 (172) | 1251 | 22.2 (212) | 787 |
Once married | 4.5 (33) | 127 | 2.3 (22) | 59 |
Christian | 64.4 (426) | 3686 | 81.4 (778) | 3089 |
Other non-Christian | 35.6 (236) | 2031 | 18.6 (178) | 698 |
12.5 (785) | 25.2 (956) |
Characteristics of circumcised men aged 10–64 years in Botswana (2008 and 2013).
Majority of men indicated that they were circumcised later in life for both surveys (56.1% in 2008 and 52.7% in 2013). However, the proportion of men who were circumcised in later life was highest in 2008. As for the place of circumcision, a high proportion of men reported that they were circumcised in a health facility, and this was high in 2013 (78.8%) than in 2008 (69%). Under one-tenth of men (9.3% in 2008 and 7.1% in 2013) reported that they experienced some complications during circumcision. The proportion of men who expressed willingness to be circumcised in was highest in 2008 (58.6%) than in 2013 (49.5%) (Table 2).
Variable | 2008 BAIS III | 2013 BAIS IV | ||
---|---|---|---|---|
% | N | % | N | |
At birth | 40.3 | 299 | 38.1 | 331 |
Later in life | 56.1 | 416 | 52.7 | 537 |
Do not know | 3.6 | 27 | 9.2 | 88 |
Health facility | 69 | 511 | 78.8 | 753 |
Traditional | 21.9 | 162 | 16.2 | 155 |
Do not know | 9.1 | 68 | 5 | 48 |
Yes | 9.3 | 69 | 7.1 | 68 |
No | 76.1 | 564 | 80.9 | 773 |
Do not know | 14.6 | 108 | 12 | 115 |
Yes | 58.6 | 3694 | 49.5 | 1270 |
No | 41.4 | 2608 | 50.5 | 1295 |
Selected key safe male circumcision variables.
Results in Table 3 present the adjusted odd ratios for the association between safe male circumcision and sociodemographic factors in 2008 and 2013. Age was observed to be a significant correlate of male circumcision in both 2008 and 2013. The odds of safe male circumcision increased with age for both survey periods, with men aged 55–64 years three times (APR = 3.40, CI = 2.00–5.76 in 2008 and APR = 3.63, CI = 2.36–5.57 in 2013) more likely to have been circumcised than men aged 10–24 years. Considering education level, men with primary or less and secondary education were less likely to have been circumcised than men with tertiary or higher education level for both survey periods.
Variable | 2008 | 2013 | ||
---|---|---|---|---|
Adjusted PR | 95% CI | Adjusted PR | 95% CI | |
10–24 | 1.00 | 1.00 | ||
25–34 | 1.76 | (1.35–2.30) | 1.36 | (1.09–1.69) |
35–44 | 2.43 | (1.73–3.41) | 1.76 | (1.35–2.29) |
45–54 | 2.54 | (1.65–3.91) | 2.41 | (1.72–3.38) |
55–64 | 3.40 | (2.00–5.76) | 3.63 | (2.36–5.57) |
Primary/less | 0.32 | (0.22–0.46) | 0.36 | (0.28–0.47) |
Secondary | 0.72 | (0.57–0.91) | 0.67 | (0.55–0.82) |
Tertiary/higher | 1.00 | 1.00 | ||
Cities and towns | 1.00 | 1.00 | ||
Urban villages | 0.79 | (0.63–1.00) | 0.90 | (0.74–1.10) |
Rural villages | 0.70 | (0.54–0.89) | 0.71 | (0.58–0.86) |
Never married | 0.43 | (0.24–0.76) | 1.10 | (0.55–2.18) |
Married | 0.68 | (0.39–1.18) | 0.93 | (0.47–1.82) |
Cohabiting | 0.45 | (0.26–0.80) | 1.05 | (0.53–2.08) |
Once married | 1.00 | 1.00 | ||
Christian | 0.81 | (0.66–1.00) | 0.95 | (0.77–1.18) |
Other non-Christian | 1.00 | 1.00 |
Adjusted prevalence ratios for the association between safe male circumcision and sociodemographic factors (2008 and 2013).
Men in rural villages were less likely to have been circumcised than men who resided in cities and towns in 2008 (APR = 0.70, CI = 0.54–0.89) and 2013 (APR = 0.71, CI = 0.58–0.86). On the other hand, there were no significant variations observed for circumcision and residing in urban villages. The odds of circumcision were significantly low among never married (APR = 0.43, CI = 0.24–0.76) and cohabiting (APR = 0.45, CI = 0.26–0.80) men than once-married men in 2008, while for married men there was no significant variation. In 2013, the odds of circumcision were significantly low among married (APR = 0.93, CI = 0.47–1.82) than once-married men, while no significant association was found for cohabiting and never married men. When considering religious affiliation, there was no variation on whether a man was from a Christian or any other religious background and circumcision.
Due to high HIV prevalence and incidence rates, inadequacy of the response programs such as PMTCT program, BCIC programs, HIV testing and counseling, blood safety program, and STI management and control gave way to safe male circumcision program. The SMC program was seen as essential in adding to the existing strategies in preventing the spread of HIV infection [17]. The combination of research findings in South Africa, Kenya, and Uganda and the WHO/UNAIDS recommendations that male circumcision is efficacious in reducing HIV infection prompted the government of Botswana to scale up this component of HIV prevention and develop national policies, strategies, and implementation plans. Although Botswana is not a traditionally circumcising society, evidence from this study indicates that male circumcision is highly acceptable in Botswana, corroborating the initial evidence [3, 5].
Majority of men who participated in the 2008 and 2013 surveys indicated that they were circumcised later in life and that they were circumcised in a health facility. A relatively low proportion of men reported that they experienced some complications during the procedure. This corroborates findings from other studies which show that when circumcision is done within hygienic clinical settings, there are minor chances of complications [1]. Common complications associated with circumcision in such settings include excessive loss of foreskin, skin bridges, amputation of the glans penis, and buried penis.
Evidence from this chapter indicates that between 2008 and 2013, the period before and after the implementation of the safe male circumcision program, the proportion of men who circumcised doubled. Although the program has not met its target [5], substantial gains have been made in getting high numbers of men to undergo circumcision. The scale-up of safe male circumcision program has benefited immensely from external funding which has supported biomedical marketing in the media including, billboard, radio, and TV advertising. Moreover, a renowned afro-pop artist was contracted as the campaign ambassador during the program in order to attract more men [5]. Additionally, specialized clinics have been set up in selected areas in addition to general public health facilities where SMC is conducted in hygienic, clinical conditions by medical practitioners [5].
On the other hand, the proportion of men who expressed willingness to undergo safe male circumcision had declined by about 10% in 2013. A plausible explanation for this decline is linked to several reasons. First, a review study on the SMC program by Katisi et al. [5] indicates that during the implementation of the program, cultural taboos such as the breaching of secrecy of the circumcision act by inclusion of women in performing circumcision procedure were introduced. Second, there are views that the traditional leadership has been left during the implementation of the program [3]. Lastly, elements of the minimum package for SMC that include counseling and voluntary HIV testing were repeatedly mentioned as other barriers that blocked men from circumcising [5]. HIV testing, in particular, seems to scare men away even if they would opt for circumcision.
Age was a significant predictor of male circumcision. For example, circumcision was found to increase with age, with highest proportions of circumcised men found in ages 55–64 years and lowest in ages 10–24 years. Similar observations were made in Uganda, where it was found that more than half of elderly men indicated that they have been circumcised compared to two-fifths of youth [30]. Although circumcision levels are lowest among young adolescents in Botswana, a study by Lane et al. [31] has shown that at the country level, deliberately prioritizing young adolescents is likely to achieve national coverage targets more quickly and cost-effectively than continuing to focus on older, harder-to-reach men. In Botswana, prioritization of younger men is critical to VMMC sustainability. As a result there is the school-going children circumcision initiative, whereby young boys are targeted to undergo circumcision through parental involvement. In this approach young boys consent to undergo circumcision through the involvement of parents. However, the decision to circumcise or not to circumcise lies with the children.
Considering education level, men with primary or less and secondary education were less likely to have been circumcised than men with tertiary or higher education level for both survey periods. This corroborates findings from other studies that men with high education and socioeconomic status have the propensity to undergo safe male circumcision compared to men with low education and poor socioeconomic status [32, 33, 34]. Educational attainment predisposes individuals to appreciate health programs better [35]. This is because men who have high education have better perception of the risk of HIV infection than men with low education. Consequently, there is need for more education and information for men with low education to take part in circumcision.
Men in rural villages were less likely to have been circumcised than men who resided in cities and towns in 2008. A plausible explanation for this scenario is that in 2008, the safe male program was not yet rolled out in the country. Moreover, men in rural areas are prone to lack of access to information and education. The odds of circumcision were significantly low among never married and cohabiting men than once-married men in 2008. This corroborates findings of a study by Mangombe and Kalule-Sabiti [36] which also found that in Zimbabwe never married and cohabiting men were less likely to circumcise. The main reason being that this cohort of men assumes that they at low risk of HIV infection. Meanwhile, other studies show the contrary that married men are at risk of infection compared to never married and cohabiting men [37].
In 2013, the odds of circumcision were significantly low among married than once-married men. Low prevalence of circumcision among married men can also be attributed to low risk of infection, especially where marital fidelity is practiced. There was no variation on whether a man was from a Christian or any other religious background and circumcision. Findings of the association between religion and circumcision are at best mixed. In some contexts, religion is a key predictor of circumcision among men [38], while in other contexts, as is the case in Botswana, it is not [39].
Safe male circumcision is as an effective additional strategy for HIV prevention. The medical benefits of SMC outweigh the risks. Age, education, residence, and marital status are significant determinants of male circumcision in Botswana. Consequently, more efforts should be geared toward educating men, especially those residing in rural areas and those in cohabiting relationships about the benefits of circumcision. Moreover, women need to be involved in understanding the benefits of male circumcision to ensure effectiveness of the SMC program.
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Professor Derbel has published many articles in journals and collaborates intensively with IntechOpen Access Publisher as an editor.",institutionString:"Clinique les Oliviers",institution:null},{id:"300144",title:"Dr.",name:"Meriem",middleName:null,surname:"Braiki",slug:"meriem-braiki",fullName:"Meriem Braiki",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/300144/images/system/300144.jpg",biography:"Dr. Meriem Braiki is a specialist in pediatric surgeon from Tunisia. She was born in 1985. She received her medical degree from the University of Medicine at Sousse, Tunisia. She achieved her surgical residency training periods in Pediatric Surgery departments at University Hospitals in Monastir, Tunis and France.\r\nShe is currently working at the Pediatric surgery department, Sidi Bouzid Hospital, Tunisia. Her hospital activities are mostly concerned with laparoscopic, parietal, urological and digestive surgery. She has published several articles in diffrent journals.",institutionString:"Sidi Bouzid Regional Hospital",institution:null},{id:"229481",title:"Dr.",name:"Erika M.",middleName:"Martins",surname:"de Carvalho",slug:"erika-m.-de-carvalho",fullName:"Erika M. de Carvalho",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/229481/images/6397_n.jpg",biography:null,institutionString:null,institution:{name:"Oswaldo Cruz Foundation",country:{name:"Brazil"}}},{id:"186537",title:"Prof.",name:"Tonay",middleName:null,surname:"Inceboz",slug:"tonay-inceboz",fullName:"Tonay Inceboz",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/186537/images/system/186537.jfif",biography:"I was graduated from Ege University of Medical Faculty (Turkey) in 1988 and completed his Med. PhD degree in Medical Parasitology at the same university. I became an Associate Professor in 2008 and Professor in 2014. I am currently working as a Professor at the Department of Medical Parasitology at Dokuz Eylul University, Izmir, Turkey.\n\nI have given many lectures, presentations in different academic meetings. I have more than 60 articles in peer-reviewed journals, 18 book chapters, 1 book editorship.\n\nMy research interests are Echinococcus granulosus, Echinococcus multilocularis (diagnosis, life cycle, in vitro and in vivo cultivation), and Trichomonas vaginalis (diagnosis, PCR, and in vitro cultivation).",institutionString:"Dokuz Eylül University",institution:{name:"Dokuz Eylül University",country:{name:"Turkey"}}},{id:"71812",title:"Prof.",name:"Hanem Fathy",middleName:"Fathy",surname:"Khater",slug:"hanem-fathy-khater",fullName:"Hanem Fathy Khater",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/71812/images/1167_n.jpg",biography:"Prof. Khater is a Professor of Parasitology at Benha University, Egypt. She studied for her doctoral degree, at the Department of Entomology, College of Agriculture, Food and Natural Resources, University of Missouri, Columbia, USA. She has completed her Ph.D. degrees in Parasitology in Egypt, from where she got the award for “the best scientific Ph.D. dissertation”. She worked at the School of Biological Sciences, Bristol, England, the UK in controlling insects of medical and veterinary importance as a grant from Newton Mosharafa, the British Council. Her research is focused on searching of pesticides against mosquitoes, house flies, lice, green bottle fly, camel nasal botfly, soft and hard ticks, mites, and the diamondback moth as well as control of several parasites using safe and natural materials to avoid drug resistances and environmental contamination.",institutionString:null,institution:{name:"Banha University",country:{name:"Egypt"}}},{id:"99780",title:"Prof.",name:"Omolade",middleName:"Olayinka",surname:"Okwa",slug:"omolade-okwa",fullName:"Omolade Okwa",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/99780/images/system/99780.jpg",biography:"Omolade Olayinka Okwa is presently a Professor of Parasitology at Lagos State University, Nigeria. She has a PhD in Parasitology (1997), an MSc in Cellular Parasitology (1992), and a BSc (Hons) Zoology (1990) all from the University of Ibadan, Nigeria. She teaches parasitology at the undergraduate and postgraduate levels. She was a recipient of a Commonwealth fellowship supported by British Council tenable at the Centre for Entomology and Parasitology (CAEP), Keele University, United Kingdom between 2004 and 2005. She was awarded an Honorary Visiting Research Fellow at the same university from 2005 to 2007. \nShe has been an external examiner to the Department of Veterinary Microbiology and Parasitology, University of Ibadan, MSc programme between 2010 and 2012. She is a member of the Nigerian Society of Experimental Biology (NISEB), Parasitology and Public Health Society of Nigeria (PPSN), Science Association of Nigeria (SAN), Zoological Society of Nigeria (ZSN), and is Vice Chairperson of the Organisation of Women in Science (OWSG), LASU chapter. She served as Head of Department of Zoology and Environmental Biology, Lagos State University from 2007 to 2010 and 2014 to 2016. She is a reviewer for several local and international journals such as Unilag Journal of Science, Libyan Journal of Medicine, Journal of Medicine and Medical Sciences, and Annual Research and Review in Science. \nShe has authored 45 scientific research publications in local and international journals, 8 scientific reviews, 4 books, and 3 book chapters, which includes the books “Malaria Parasites” and “Malaria” which are IntechOpen access publications.",institutionString:"Lagos State University",institution:{name:"Lagos State University",country:{name:"Nigeria"}}},{id:"273100",title:"Dr.",name:"Vijay",middleName:null,surname:"Gayam",slug:"vijay-gayam",fullName:"Vijay Gayam",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/273100/images/system/273100.jpeg",biography:"Dr. Vijay Bhaskar Reddy Gayam is currently practicing as an internist at Interfaith Medical Center in Brooklyn, New York, USA. He is also a Clinical Assistant Professor at the SUNY Downstate University Hospital and Adjunct Professor of Medicine at the American University of Antigua. He is a holder of an M.B.B.S. degree bestowed to him by Osmania Medical College and received his M.D. at Interfaith Medical Center. His career goals thus far have heavily focused on direct patient care, medical education, and clinical research. He currently serves in two leadership capacities; Assistant Program Director of Medicine at Interfaith Medical Center and as a Councilor for the American\r\nFederation for Medical Research. As a true academician and researcher, he has more than 50 papers indexed in international peer-reviewed journals. He has also presented numerous papers in multiple national and international scientific conferences. His areas of research interest include general internal medicine, gastroenterology and hepatology. He serves as an editor, editorial board member and reviewer for multiple international journals. His research on Hepatitis C has been very successful and has led to multiple research awards, including the 'Equity in Prevention and Treatment Award” from the New York Department of Health Viral Hepatitis Symposium (2018) and the 'Presidential Poster Award” awarded to him by the American College of Gastroenterology (2018). He was also awarded 'Outstanding Clinician in General Medicine” by Venus International Foundation for his extensive research expertise and services, perform over and above the standard expected in the advancement of healthcare, patient safety and quality of care.",institutionString:"Interfaith Medical Center",institution:{name:"Interfaith Medical Center",country:{name:"United States of America"}}},{id:"93517",title:"Dr.",name:"Clement",middleName:"Adebajo",surname:"Meseko",slug:"clement-meseko",fullName:"Clement Meseko",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/93517/images/system/93517.jpg",biography:"Dr. Clement Meseko obtained DVM and PhD degree in Veterinary Medicine and Virology respectively. He has worked for over 20 years in both private and public sectors including the academia, contributing to knowledge and control of infectious disease. Through the application of epidemiological skill, classical and molecular virological skills, he investigates viruses of economic and public health importance for the mitigation of the negative impact on people, animal and the environment in the context of Onehealth. \r\nDr. Meseko’s field experience on animal and zoonotic diseases and pathogen dynamics at the human-animal interface over the years shaped his carrier in research and scientific inquiries. He has been part of the investigation of Highly Pathogenic Avian Influenza incursions in sub Saharan Africa and monitors swine Influenza (Pandemic influenza Virus) agro-ecology and potential for interspecies transmission. He has authored and reviewed a number of journal articles and book chapters.",institutionString:"National Veterinary Research Institute",institution:{name:"National Veterinary Research Institute",country:{name:"Nigeria"}}},{id:"158026",title:"Prof.",name:"Shailendra K.",middleName:null,surname:"Saxena",slug:"shailendra-k.-saxena",fullName:"Shailendra K. Saxena",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRET3QAO/Profile_Picture_2022-05-10T10:10:26.jpeg",biography:"Professor Dr. Shailendra K. Saxena is a vice dean and professor at King George's Medical University, Lucknow, India. His research interests involve understanding the molecular mechanisms of host defense during human viral infections and developing new predictive, preventive, and therapeutic strategies for them using Japanese encephalitis virus (JEV), HIV, and emerging viruses as a model via stem cell and cell culture technologies. His research work has been published in various high-impact factor journals (Science, PNAS, Nature Medicine) with a high number of citations. He has received many awards and honors in India and abroad including various Young Scientist Awards, BBSRC India Partnering Award, and Dr. JC Bose National Award of Department of Biotechnology, Min. of Science and Technology, Govt. of India. Dr. Saxena is a fellow of various international societies/academies including the Royal College of Pathologists, United Kingdom; Royal Society of Medicine, London; Royal Society of Biology, United Kingdom; Royal Society of Chemistry, London; and Academy of Translational Medicine Professionals, Austria. He was named a Global Leader in Science by The Scientist. He is also an international opinion leader/expert in vaccination for Japanese encephalitis by IPIC (UK).",institutionString:"King George's Medical University",institution:{name:"King George's Medical University",country:{name:"India"}}},{id:"94928",title:"Dr.",name:"Takuo",middleName:null,surname:"Mizukami",slug:"takuo-mizukami",fullName:"Takuo Mizukami",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/94928/images/6402_n.jpg",biography:null,institutionString:null,institution:{name:"National Institute of Infectious Diseases",country:{name:"Japan"}}},{id:"233433",title:"Dr.",name:"Yulia",middleName:null,surname:"Desheva",slug:"yulia-desheva",fullName:"Yulia Desheva",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/233433/images/system/233433.png",biography:"Dr. Yulia Desheva is a leading researcher at the Institute of Experimental Medicine, St. Petersburg, Russia. She is a professor in the Stomatology Faculty, St. Petersburg State University. She has expertise in the development and evaluation of a wide range of live mucosal vaccines against influenza and bacterial complications. Her research interests include immunity against influenza and COVID-19 and the development of immunization schemes for high-risk individuals.",institutionString:'Federal State Budgetary Scientific Institution "Institute of Experimental Medicine"',institution:null},{id:"238958",title:"Mr.",name:"Atamjit",middleName:null,surname:"Singh",slug:"atamjit-singh",fullName:"Atamjit Singh",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/238958/images/6575_n.jpg",biography:null,institutionString:null,institution:null},{id:"252058",title:"M.Sc.",name:"Juan",middleName:null,surname:"Sulca",slug:"juan-sulca",fullName:"Juan Sulca",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/252058/images/12834_n.jpg",biography:null,institutionString:null,institution:null},{id:"191392",title:"Dr.",name:"Marimuthu",middleName:null,surname:"Govindarajan",slug:"marimuthu-govindarajan",fullName:"Marimuthu Govindarajan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/191392/images/5828_n.jpg",biography:"Dr. M. Govindarajan completed his BSc degree in Zoology at Government Arts College (Autonomous), Kumbakonam, and MSc, MPhil, and PhD degrees at Annamalai University, Annamalai Nagar, Tamil Nadu, India. He is serving as an assistant professor at the Department of Zoology, Annamalai University. His research interests include isolation, identification, and characterization of biologically active molecules from plants and microbes. He has identified more than 20 pure compounds with high mosquitocidal activity and also conducted high-quality research on photochemistry and nanosynthesis. He has published more than 150 studies in journals with impact factor and 2 books in Lambert Academic Publishing, Germany. He serves as an editorial board member in various national and international scientific journals.",institutionString:null,institution:null},{id:"274660",title:"Dr.",name:"Damodar",middleName:null,surname:"Paudel",slug:"damodar-paudel",fullName:"Damodar Paudel",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/274660/images/8176_n.jpg",biography:"I am DrDamodar Paudel,currently working as consultant Physician in Nepal police Hospital.",institutionString:null,institution:null},{id:"241562",title:"Dr.",name:"Melvin",middleName:null,surname:"Sanicas",slug:"melvin-sanicas",fullName:"Melvin Sanicas",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/241562/images/6699_n.jpg",biography:null,institutionString:null,institution:null},{id:"117248",title:"Dr.",name:"Andrew",middleName:null,surname:"Macnab",slug:"andrew-macnab",fullName:"Andrew Macnab",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of British Columbia",country:{name:"Canada"}}},{id:"322007",title:"Dr.",name:"Maria Elizbeth",middleName:null,surname:"Alvarez-Sánchez",slug:"maria-elizbeth-alvarez-sanchez",fullName:"Maria Elizbeth Alvarez-Sánchez",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Universidad Autónoma de la Ciudad de México",country:{name:"Mexico"}}},{id:"337443",title:"Dr.",name:"Juan",middleName:null,surname:"A. Gonzalez-Sanchez",slug:"juan-a.-gonzalez-sanchez",fullName:"Juan A. Gonzalez-Sanchez",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Puerto Rico System",country:{name:"United States of America"}}},{id:"337446",title:"Dr.",name:"Maria",middleName:null,surname:"Zavala-Colon",slug:"maria-zavala-colon",fullName:"Maria Zavala-Colon",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Puerto Rico, Medical Sciences Campus",country:{name:"United States of America"}}}]}},subseries:{item:{id:"93",type:"subseries",title:"Inclusivity and Social Equity",keywords:"Social Contract, SDG, Human Rights, Inclusiveness, Equity, Democracy, Personal Learning, Collaboration, Glocalization",scope:"