Typical catalyst properties for residue hydrocracking.
\r\n\tTo viable rural development has a vital role for rural communities. In the design of policies to be successful that affect them rural people have to decide and implement. According to this, it is a critical point to involve the poor and disadvantaged, along with related stakeholders, agricultural and rural development. Hence, for the sustainable development by international initiatives and all other institutions were searched and to be present the agricultural and related research results. To help support the effort, various governmental and non-governmental agencies established fundings for sustainable rural development research and fostered the development of human well-being goals in rural areas via national and international initiatives. In this context, most efforts resulted in successful cases. This book will intend to provide the reader with a comprehensive overview of the theory, approaches, strategies, and cases, and key elements and challenges of sustainable development, and Bioeconomy, Green and Circular economy for sustainability, and UN SDGs-Agenda 2030 and EU Green Deal.
\r\n\r\n\tI believe that this work will be fundamental in the field of SDG, and it will be a guiding, idea-generating key for researchers, practitioners, rural community, and policy decision-makers, and I hope that together we will establish sustainable rural life and development around the world.
\r\n\t
The increasing world population and economic growths cause significant increases in oil demand. With the finite conventional fossil fuel reserves, the production based on alternative renewable sources and nonconventional oils such as heavy crude oils and tar sand bitumen is expected to increase. Heavy oil, as the general term for nonconventional heavy feedstock, is considered as an alternate suitable source for transportation fuels, energy, and petrochemicals to fulfill the requirements of modern civilization [1]. This indicates that processing of heavy oils in the petroleum refining industries is growing.
\nIn general, heavy oil is defined as any liquid petroleum with an API gravity less than 20°. API gravity is an expanded density scale used widely in petroleum industry. Heavy oil with API gravity below 10.0°API sinks under the water as it is heavier compared with water (10.0°API), and it is termed extra-heavy oil [2]. Compared with conventional light oil, heavy oils have higher viscosity, higher density, and lower API gravity. The properties of heavy oils vary according to its origin and synthetic route.
\nThe main issue with heavy crude oil is that it produces a lower percentage of gasoline and diesel fuels and a higher percentage of residue fraction when distilled by an oil refinery. In addition, heavy crude oil has more negative impacts to the environment than its light counterpart, and its refining requires the use of more advanced techniques. Petroleum residues are the heavy fraction remaining after distilling petroleum crudes at atmospheric pressure (atmospheric residue) or at reduced pressure of 25–100 mmHg (vacuum residue; boiling point >525°C). Petroleum residue has high average molecular weight (> 1000 Da number average for vacuum residue) and higher asphaltene content [3]. Asphaltenes are insoluble in n-alkanes such as n-pentane and n-heptane but soluble in benzene or toluene [4]. In addition, residues have high heteroatom content such as sulfur (∼ 5 wt%), nitrogen, and heavy metal (i.e., vanadium and nickel > 100 ppm). These heteroatoms tend to poison catalysts and cause problems during processing and, therefore, need special processing in the refinery to remove them.
\nPetroleum residues can be converted into lighter oil or more value-added products using bottom-of-the-barrel conversion processes or residue upgrading processes [1]. No matter which type of process is used, a substantial fraction of residue molecules can be cracked off as fragments to become liquids in the transportation fuel and vacuum gas oil boiling ranges. However, due to the high asphaltene content, overly converted residues can push the selectivity toward the thermodynamically favored but lower valued products, namely, coke and hydrocarbon gases.
\nHydrogen addition and carbon rejection are the two major approaches to upgrade petroleum residues into lighter oils in petroleum industry. Carbon rejection, such as coking process, produces a lot of cokes during the heavy oil upgrading processes which have low or no market value. In the past few decades, hydrogen addition approach especially hydroprocessing has gained prominence in heavy oil or vacuum residue upgrading processes [1]. This approach upgrades heavy feeds to distillate fractions and generates less coke.
\nVarious hydroprocessing reactor technologies such as fixed-bed, ebullated-bed, or slurry-phase reactors are used to upgrade heavy residues [5]. The principles of these reactor operations are almost the same but differing with respect to some technical minutiae and tolerance of impurities [1, 6]. Typically, hydroprocessing of heavy oils is an upgrading process carried out at temperature around 380–480°C and hydrogen pressure at 80–270 bar with the presence of a catalyst [7]. H-Oil™ and LC-Fining are the processes designed to convert heavy residue to lighter fractions by hydroprocessing using an ebullated-bed reactor. Eni slurry technology (EST) and CanMet by Energy Research Laboratories, Canada, are examples that are using slurry-phase reactors.
\nIn general, hydroprocessing involves hydrocracking and hydrotreating. The main objective in heavy feedstock upgrading is to convert heavier residue into lighter distillates in such a way to increase hydrogen-to-carbon (H/C) ratio of the product. Thus, hydrocracking reaction is the main concern. Hence, sometimes hydroprocessing of heavy oils is also called hydrocracking of heavy oils. During the process, larger molecules such as asphaltenes and resins are cracked and being converted to lighter liquid hydrocarbons such as gasoline, diesel, and gas oil. Meantime, various hydrotreating reactions such as hydrodesulfurization (HDS), hydrodenitrogenation (HDN), and hydrodemetalation (HDM) are also occurring during the process under the operating conditions. This leads to better product oil quality and contributes toward hydrotreating process in the later stage.
\nHydroprocessing is the most versatile of the modern heavy feed conversion processes. The flexibility of the operating conditions with respect to both the feedstock and product separation has provided the most economical refinery balance relative to supply and demand [1]. Catalyst plays an important role attributed to this flexibility in hydroprocessing, in which upgrading the most problematic feeds such as vacuum residue is derived from heavy crudes, as well as the direct upgrading of the latter. During reactions, catalyst helps to reduce the activation energies leading to higher yield and selectivity for the products in favor. Various factors influence the product selectivity; these include reaction operating conditions and catalyst properties such as active sites, shape, size, chemical compositions, etc.
\nReaction operating conditions associate directly with the productivity. Heavy oil hydrocracking is typically carried out at a relatively higher temperature. Since the reaction operating conditions for different technologies are different, to ensure the desirable yield and selectivity, it is important to consider the characteristics of the feed, appropriate reactor system, and catalysts for the hydrocracking of vacuum residue [1].
\nFor different types of reactor operation, the catalyst properties especially the catalyst particle sizes deployed also vary. The typical catalyst properties used in different types of reactors are given in Table 1.
\nReactor type | \nCatalyst size, mm [8, 9] | \nCatalyst in reactor, particle/cm3 [9] | \n
---|---|---|
Fixed bed | \n∼1.2–3.0 | \n120 | \n
Ebullated bed | \n∼0.8 | \n250 | \n
Slurry system | \n∼0.002 | \n2.4 × 109 | \n
Typical catalyst properties for residue hydrocracking.
Generally, supported sulfide catalysts containing group VIB and VIII metals especially cobalt, molybdenum, tungsten, or nickel are used in heavy oil upgrading processes. However, impurities present such as heavy metals in the residues decrease the catalytic activities [1, 10].
\nEstablishing an understanding of the key catalyst properties that influence catalyst performance in hydrocracking of heavy residue is important. This provides a basis to develop a better-performance catalyst for heavy oil hydrocracking.
\nHydrocracking reactions require a bifunction catalyst with high cracking and hydrogenation activities. The high cracking activity is provided by an acidic support, whereas the hydrogenation activity is provided by metals on the support. The acidic catalyst support, such as acid-treated clay, alumina, or silica-alumina, is used to promote cracking and support the metals such as nickel, tungsten, platinum, and palladium that supply the hydrogenation function. These highly acidic catalysts are sensitive to the feed with high-nitrogen compound, which easily neutralizes the acid sites. Therefore, catalyst used for heavy oil hydrocracking process is different from the normal distillate hydrocracking process. Further, heavy oil that is derived from different geographical areas possess different properties. Therefore, it is important to have a specific designed catalyst that is suitable to the targeted heavy oil hydrocracking. Here, a key challenge is to design and synthesize catalysts that have high activity for hydroprocessing. Main components in catalyst design for hydroprocessing of heavy oils are discussed in the following sections.
\nCracking of C▬C bonds require a high amount of energy; therefore, hydrocracking reactions occur significantly only at high temperature (∼400°C and above). The main function of catalysts is to provide hydrogenation-dehydrogenation reactions that lead to higher liquid hydrocarbon yield and suppress coke formation. Platinum-group precious metals such as platinum and palladium are the representative catalysts with excellent hydrogenation capacity, and they are also commonly used in many other reactions. However, these platinum-group precious metals showed weak resistance especially to sulfur [11]. Sulfur escapes and reacts with the catalyst during upgrading process as extra-heavy oil containing high concentration of sulfur [12]. Therefore, in order to cope with heavy residue, which is high in sulfur content and other impurities such as nitrogen, and heavy metals that can easily deactivate or poison the catalyst, platinum-group precious metals have not been used as catalysts for the upgrading of extra-heavy oil.
\nMo, Ni, Co, and W are the common established transition metals used as the active ingredient in catalyst for hydrocracking of heavy residue. Sulfides of Mo and W are usually used, and Ni and Co are used in promoting species components in the petroleum industry. These metal sulfides not only promote relatively high hydrogenation but are also good in hydrotreating activities such as HDN, HDS, and HDM during heavy residue upgrading process. The abovementioned metal sulfides are favored as well in terms of their availability and the cost comparing to the noble metals such as platinum and palladium. There are also studies on using other promoters such as phosphorus (P), fluorine (F), and boron (B) on the catalysts [1].
\nThe reactive metals are usually deposited on catalyst support by wet or incipient wetness impregnation methods. The impregnated catalysts are then calcined, reduced, and used for the hydrocracking reactions.
\nSulfides of metals, e.g., MoS2 and WS2, have been used as the active phase in hydrocracking catalyst. NiMo and CoMo sulfides were identified to exhibit superior HDS activity [13, 14].
\nSulfidation of supported oxidative metal catalysts is normally carried out by thermally reacting with sulfur compound prior to hydroprocessing in order to have the best catalyst performance. For dispersed catalyst, sulfidation of the catalyst can be done either ex situ or in situ. Most oil-soluble catalyst metal precursors, which are available in the oxide, can be sulfided in situ by thermally decomposing sulfur compound in the heavy residue upon the reaction severity and transformed from inactive oxides to sulfides during the upgrading process [15]. However, the complete sulfidation of active components can be challenging [16], and incomplete sulfidation reduces the catalyst performance to a certain degree. Dispersed metal oxide catalyst can also be presulfided ex situ by using H2S as the sulfiding agent followed by dispersion in oils [14].
\nSulfidation is a complex reaction. Strong interaction between metal and support can cause poor reducibility of the metal species, which eventually makes the sulfidation of the catalyst difficult and leads to poor activity [17]. In spite of similar activities for the hydrocracking reaction, W-based catalysts have received less attention than Mo catalysts. This is due to their lower sulfidation ability, on which the catalytic activation is strongly dependent [18].
\nCarbide catalysts are also being tested in heavy residue upgrading [19, 20]. Studies have shown that the electron distribution of the
Catalyst support plays an important role in a catalyst. Support provides space for the active metal to stay upon as well as acid sites for cracking activity. Large surface area of support is generally favorable for catalyst as it can be interpreted directly into more active sites available on the catalyst surface which normally lead to better catalyst performance. Porous structure support exhibits large surface area. Hence, other than the chemical composition of catalyst, textural properties of support such as size, shape, surface area, and porosity have a great influence especially for heterogeneous catalyst system.
\nAcid sites of the catalyst promote cracking activity. Materials such as alumina, crystalline zeolite, amorphous silica-alumina, and mixture of crystalline zeolite and amorphous oxides with high acidity (Lewis and Brønsted acid sites) are used as catalyst base or support in order to promote more cracking activity during reactions. These supports usually have a structure with numerous micropores (pore diameter < 2 nm), which provide high surface area and acidic properties [24].
\nIn terms of chemistry at the molecular level, zeolites and amorphous silica-alumina share some similarities. However, zeolites, which have the crystalline structure, offer higher activities and better controlled selectivity than the amorphous materials. Typically, using zeolite-based catalysts in hydrocracking results in greater cracking activity owing to its greater acidity. In addition, the use of zeolite-based catalyst improves thermal or hydrothermal stability and resistance to nitrogen/sulfur compounds.
\nHowever, catalyst deactivation occurs quickly when these conventional supported catalysts are used in heavy residue hydroprocessing. This is due to pore blocking caused by relatively high concentrations of heteroatoms, metal poisoners, and asphaltenes commonly found in heavy fractions. This significantly reduces the availability and accessibility of the active sites at the catalyst surface in the pores by the reactant molecules. Hence, conventional supports are not suitable for upgrading of extra-heavy oils and vacuum residues. It is also believed that the catalyst support’s intrinsic acid sites (e.g., γ-Al2O3) participate in sediment or coke formation during hydrocracking reaction [25]. To avoid pore blocking problem, this leads to the introduction of meso (2–50 nm)/macropores and high pore volume into the catalyst support for hydrocracking catalyst.
\nTherefore, greater attentions are paid to the properties of catalyst especially support materials such as the size of the particles, pore volume and pore size distribution, and the shape of the particles to maximize utilization of the catalyst.
\nHigh asphaltene content in heavy oils leads to a higher tendency to form coke during processing compared to conventional light crude oils. This is due to the accumulation of the coke precursors on both external and internal configurations of the catalyst. In addition, rapid deposition of metallic poisons narrows down the catalyst pore size, restricting the accessibility by reactant species and products. These may cause complete pore blockage. As a result, the catalyst activities and performance reduce markedly. Hence, typical good catalyst design for heavy oils upgrading processing must offer (1) accessibility to large asphaltene agglomerates in order to increase their diffusion and transformation and (2) catalytic active sites or support adsorption sites that are less favorable to sediment or coke formation [3]. Also, it is clear that the pore structure of the catalyst has a close relationship with the conversion, selectivity, and stability properties of the catalysts during hydrocracking reaction [26].
\nIn order to overcome the difficulty of asphaltene diffusion through small pores, the development of the porous shaped support or catalyst structure with macropores (>100 nm) is rationalized. However, too many macropores (ca. above 30% of total pore volume) should not be created, since shaped particles could turn fragile [3]. Mesoporous alumina is a rigid porous material with a mutually interconnected or isolated network structure which has not only the characteristics of a crystalline phase of alumina but also the characteristics of a porous material [27]. Catalysts having pores between 7 and 20 nm diameter showed higher activities than those catalysts having pores between 3 and 7 nm which was reported for hydrocracking of Athabasca oil sand bitumen [28]. In order to retain the mechanical strength, stability, and accessibility to large asphaltene agglomerates of the catalyst during heavy residue hydrocracking reaction, the multimodal porous structures or hierarchical pore system is developed in hydrocracking catalyst. Hierarchical pore system in catalyst not only integrates different functionalities in the catalyst but also allows the realization of a multiple step reaction in one single catalyst in a cascade way without any separation processes.
\nHydrotreating effect especially HDS of atmospheric residue is a well-established residuum upgrading process which requires catalysts designed to remove and accumulate metals and to desulfurize the feed [8]. A wide-pore NiMo/γ-alumina was tested for its performance in a vacuum residue hydroprocessing. The catalyst showed a remarkably high activity for HDM and asphaltene conversion reactions in the vacuum residue hydroprocessing [29].
\nOther than active metal and phase, pore size distribution has been found to affect the catalyst activity in hydroprocessing of vacuum residue. A hydroprocessing study using Kuwait vacuum residue as feedstock has shown that the effect of catalyst pore size was significantly different for different hydrotreating reactions [30]. Sulfided NiMo catalysts with unimodal and bimodal distributions with different proportions of meso- and macropores were prepared. For sulfur removal (HDS), a unimodal pore catalyst with maximum pore volume in the medium mesopore range (10–25 nm diameter) showed the highest activity. For HDM and HDN reactions, large-pore catalysts, having a major proportion of pore volume in 100–300 nm diameter pores, were found to be more effective.
\nγ-Al2O3 is the most commonly used support in catalysis for hydroprocessing. There are methods developed to prepare mesoporous and hierarchical texture support for hydrocracking catalyst. Two most important techniques for preparation of the material with the desired hierarchical texture are by hydrothermal and template methods.
\nHydrothermal method is an approach where the mixed solution (aluminum precursor, solvent, etc.) is poured into a sealed reactor. In the reactor, relatively high-temperature and high-pressure conditions promote the dissolution and recrystallization of poorly soluble or insoluble material. γ-Al2O3 is then produced by calcination of precipitated hydroxides [27, 31]. During the hydrothermal process, under the nonrestricted conditions, the crystal grows to its largest possible size, and its various characteristics such as shapes, high degree of crystallinity, uniform distribution, and lighter particle agglomeration are developed [32]. The hydrothermal conditions such as water temperature, pressure, and viscosity of the solution are closely related to the development of the crystal morphology. The same type of crystal can be produced with different morphologies under different hydrothermal conditions [27, 33].
\nStanislaus et al. [29] studied the mechanism of pore widening in γ-alumina under hydrothermal conditions in the presence and absence of additives such as P, F, phenol, and acetic acid. The formation and growth of boehmite into large crystallites by rehydration of γ-alumina were found responsible for pore enlargement. Li et al. [34] synthesized alumina from aluminum ammonium sulfate, urea, and polyglycol 2000 by hydrothermal method. It was reported that mesopore alumina of different morphologies can be fabricated merely by adjusting hydrothermal temperature.
\nTemplate method is a technology which is widely applied in recent years. It is a synthetic method for controlling the structure, particle size, and morphology of materials through utilization of a template [27].
\nMesoporous alumina is normally prepared via surfactant templates. Su et al. [35] used Al2(SO4)3 and NaAlO2 as aluminum precursors for preparing lamellate structure mesoporous alumina with crystalline framework walls in the presence of nonionic surfactant PEG6000. Well-crystallized mesoporous γ-alumina was formed after the samples were calcined at 600°C for 3 h. Mesoporous alumina prepared in this way exhibited a large surface area (279 m2/g) and a very rich porosity with large mesopores, and both the pore volumes and the pore sizes increased with the addition of the surfactant in the precipitation process [35].
\nZhou et al. [36] used a promising strategy to prepare well-defined and uniform pore structure (WDUPS) Al2O3 by coating specially treated SiO2 opals with Al2O3. The pore size of the WDUPS Al2O3 was tailored in the range of meso- to macro-size by using microspheres of different sizes to fabricate the SiO2 opal. When the SiO2 opals were coated with optimal amount of Al2O3, the obtained WDUPS Al2O3 showed a uniform acid density.
\nRecently, another hard template method, which uses polystyrene (PS) microspheres, was used to prepare a range of hierarchically porous alumina samples. The alumina precursor was mixed either with dry powder of PS microspheres (dry) or PS water suspension (wet) during preparation before pelletizing and calcination. The “wet” method gives pellets with a narrower distribution of macropores in size and the greater material mechanical strength. The approach allows tuning textural parameters of hierarchically porous alumina samples in different ranges of specific surface, mesopore volume, and total pore volume [37].
\nIn a recent review by Galadima and Muraza [38] on hierarchical zeolites in hydrocracking catalysts, in general, the generation of the mesoporous zeolite systems could be achieved either during the initial crystallization process or through post-synthesis treatment processes. In either case, the resulting materials could have hierarchical arrangement of pore system or unimodal system. Another strategy adopted is the application of hard templates for synthesizing hierarchical zeolite. For achieving an efficient mass transport and high catalytic performance, the design of hierarchically porous catalytic supports is an interesting and most effective strategy.
\nThe catalytic activity is related to the structure of the catalyst. Daage and Chianelli [39] proposed the “rim-edge” model of MoS2 for hydrotreating, in which two kinds of exterior sites are responsible for hydrogenation (HYD) and hydrodesulfurization (HDS) (Figure 1). MoS2 forms hexagonal or triangular slabs, and the rim sites around the exposed basal planes contribute to both HYD and HDS, and the exposed edge sites around the interior layers of MoS2 stacks are accepted as active sites only in HDS.
\nRim-edge model [
The number of stacking layers of MoS2 was then reported to increase the hydrogenation activity by promoting planar adsorption of aromatic rings on the edge sites [40]. Later, Lauritsen et al. [41] proposed the “brim site” model as the active site of HDS, based on observations of MoS2 nanoparticles using scanning tunneling microscopy. The brim sites associated to Mo edges that are fully sulfided exhibit electron exchange capability as in typical metal catalysts.
\nIn 2014, Chen et al. [42] compared the structure of hexagonal and triangular MoS2 catalysts with their activities in hydrotreating. The hexagonal MoS2 with more Mo edge sites was reported to have higher activity in HYD, but the triangular MoS2 with more S-edge sites exhibited higher activity in HDS.
\nSimilar catalyst structure-activity relations have also been found for W-based catalyst. In 2016, a DFT study that seeks to understand the active sites of “W-edge” or “S-edge” of NiWS phases showed that the surface concentration of “W-edge” and “S-edge” sites is closely related to the intrinsic hydrogenation activity of NiWS catalyst [43].
\nLow-quality heavy feedstock leads to quick catalyst deactivation, high coke formation, and large pressure drop in the operation of a fixed-bed reactor. In such a case, ebullated-bed or slurry-phase reactors can be an effective choice. These are systems designed with continuous addition and withdrawal of catalyst which allow one to control the catalyst deactivation due to coke formation as well as thermal exchanges in the reactor.
\nSupported catalysts are usually used in a fixed-bed or ebullated-bed reactor system for heavy oil hydroprocessing. On the other hand, nano-size unsupported dispersed catalysts are used in a slurry-phase reactor. In this case, the catalyst is in dispersed form such as unsupported metal particles, oil-soluble metals, or metal precursors that form in situ active phase during the process. Slurry-phase hydrocracking processes exhibit high selectivity and yield toward the product. For slurry-phase hydrocracking process of vacuum residue, both heterogeneous and homogeneous catalysts, depending upon the physical properties of the catalyst, are used. Catalyst development for heavy residue hydroprocessing is always ongoing for a better-performance catalyst and a longer catalyst run-length.
\nCarbon or carbon black has been tested as catalyst support for hydroprocessing. It is cheap and has a low tendency to form coke-related compounds (due to very weak acid sites). It has an affinity for V and Ni porphyrine-like compounds, which could be refrained from poisoning the catalyst by attacking the catalyst active sites. Meantime, it also has high HDS and HDN activities [44] and has no micropores below 3 nm which could be easily occluded, therefore turning active Ni and Mo metals into inactive ones [3]. However, carbon or carbon black supports are known for their low mechanical resistance since the structure of shaped catalyst particles easily collapses especially when used as catalyst in the ebullated-bed reactor [3]. To overcome the aforementioned mechanical resistance issue, a bimodal alumina modified with (8–18 wt%) carbon black composite support, containing 11–20% of total pore volume as macropores (>100 nm), was developed, and these prospective supports were impregnated with Ni and Mo. The addition of carbon black to alumina, after inert atmosphere pyrolysis, has produced strong shaped particles, suitable for high-colliding attrition applications, as commonly found in the ebullated-bed reactors. HDS and HDN can be enhanced when combining carbon black and macropores. It is also noted that catalysts containing macropores were reported more efficient in HDM than catalysts containing no macropores [3].
\nA series of mesoporous alumina catalysts with different textural properties were prepared by using the sol-gel method with the varied aluminum precursor, chain length of the surfactant, and calcination temperature. Mesoporous alumina with large surface area (270–380 m2/g) and pore size (3–19 nm) was successfully synthesized. The activity of mesoporous alumina-supported molybdenum catalysts with different properties in hydrocracking of residual oil was determined at 400°C. Higher conversion and higher liquid yield were achieved by using catalysts with larger mesopore size than catalysts with smaller pore size and similar acidity [45].
\nDong et al. [46] synthesized a nest-like hollow γ-AlOOH microspheres constructed from numerous hierarchically organized nanowires via a template-free simple hydrothermal approach, from which hierarchically porous γ-Al2O3 microspheres with average macropores of 900 nm, mesopores of 20 nm, and a pore volume of 0.93 cm3/g were obtained readily. The nest-like γ-Al2O3 microspheres were tested as catalyst supports. The prepared MoNi/γ-Al2O3 (hierarchically pore texture)-supported catalyst was applied for HDM catalysis. The catalysts exhibited superior catalytic performance and longer life due to enhanced diffusion of the reactants, compared to the catalysts prepared with the commercial γ-Al2O3.
\nA theoretical estimation of catalyst performance using geometrical characteristics of the porous media based on Monte Carlo methods and the graph theory was done on evolution of alumina catalyst texture during macromolecule conversion in heavy oil hydroprocessing [47]. In this study, a unimodal mesoporous structure of conventional catalyst and bimodal meso-/macroporous structure of the catalyst were modeled. Deactivation was modeled by the monotonic increase of alumina grain radius, which represented deposition of coke and metal species onto the surface of grains. There was a correlation observed for the hierarchical texture model and the experiment. Both the hierarchical texture in model and experiment were with prolonged catalyst lifetime.
\nA series of NiMoS/γ-Al2O3 catalysts were prepared with varying Mo loading amounts, Ni addition, P addition, and porosity of γ-Al2O3 support, in order to design a suitable catalyst for hydrocracking of vacuum residue. Activity tests were conducted in an autoclave batch reactor at 420°C and 10 MPa H2 in the presence of 0.26 wt% catalyst and 33.0 wt% tetralin. The amount of Mo loadings on γ-Al2O3 was observed most favorable at 8.0 wt% with the asphaltene conversion of 62.9%. The addition of Ni had minimal effect on the vacuum residue hydrocracking but significant effect on the HDS activity. The increase in porosity of the γ-Al2O3 support reported to play an important role in enhancing the asphaltene conversion to 68.5% [48].
\nThese metal-supported catalysts exhibit good performance in HDM, HDS, and hydrocracking reactions. However, when upgrading extra-heavy oil using these metal-supported catalysts, a critical problem of a short lifetime can result from deactivation of the active sites due to coke or sulfur deposition [14]. Hydrocracking processes that use heterogeneous catalyst of fixed-bed, ebullated-bed, or slurry reactors are always with the problems of feed diffusion, pressure drop, and mass transfer. The intraparticle mass transfer between liquid and solid phases, particle size, and mixing matter which must be taken into consideration [49]. All these concerns make limitations to feedstock used for the commercial application. Application of dispersed catalyst in slurry-phase hydrocracking is an alternate option to resolve these issues.
\nCoke formation resistance is vital to a hydrocracking catalyst since it determines the durability and lifetime of the catalyst. It is known that coke formation is markedly inhibited when the active species are applied as dispersed nanoparticle catalysts [14]. The application of the highly dispersed catalysts in the slurry-phase hydroprocessing of heavy residues favors the rapid uptake of hydrogen and deactivates the intermediate free radical moieties in the liquid phase, thereby suppressing coke formation, increasing total conversion, and enhancing quality of liquid product [50].
\nDispersed catalyst can be classified into either water-soluble or oil-soluble [50]. Oil-soluble dispersed catalyst is generally preferred because it has a better catalyst activity as it can disperse uniformly in oil. To prepare oil-soluble dispersed catalysts, metals are usually introduced into the oil-soluble precursors to form an organometallic compound [1]. The metal precursors are then homogeneously dispersed in the reactor containing heavy oil or residue. The catalyst precursor will be activated (sulfided) in situ by reacting with the sulfur compound in the oil. Typical oil-soluble dispersed catalysts are such as molybdenum naphthenate and ammonium heptamolybdate [51]. For a water-soluble catalyst, pretreatments such as dispersion, emulsion, and dehydration are needed [1].
\nCatalyst or catalyst precursor and its dispersibility in the oil during the hydroprocessing of vacuum residue have direct correlation to the system performance. Among the transition metals, Mo- and W-based dispersed catalysts have been the focus of the study in hydrocracking of extra-heavy oils or vacuum residue. For instance, exfoliated MoS2 was applied as a dispersed catalyst for Cold Lake bitumen upgrading [52].
\nIn [52], the exfoliated MoS2, a two-dimensional MoS2 material, was prepared via chemical exfoliation of MoS2 particles that were dispersed in water. The results were compared with MoS2 prepared in situ by the decomposition of molybdenum naphthenate. Although liquid yield and coke suppression were similar among those mentioned catalysts, a better hydrogenation activity, especially HDN, and asphaltene and microcarbon residue (MCR) removal were obtained with the exfoliated MoS2 [52, 53]. The improved hydrogenation is believed to be a consequence of increased rim-edge sites [39] associated with the exfoliated MoS2.
\nIn the case of using tungsten, unsupported nickel tungsten sulfide (NiWS(
Nano-sized tungsten carbide (2.8 nm) particles were synthesized using removable ceramic coating method and then were applied as dispersed catalysts to hydrocracking of vacuum residue, which was carried out at 400°C for 4 h with initial hydrogen pressure of 70 bar. The temperature programmed desorption analysis results showed that nano-sized tungsten particles are capable of superior hydrogen adsorption (compared to bulk tungsten carbide) as well as high catalytic performance, not only in commercial liquid yield (naphtha, middle distillate, and gas oil; 46.7 wt.%) but also in coke formation (5.9 wt.%) [20].
\nThe effects of Co, Ni, or Mo precursors that have different oil solubility and oxidation state on the slurry-phase hydrocracking of vacuum residue at 400°C and 9.5 MPa H2 were reported in [54]. The metal precursors were found to form nanoscaled dispersed particles of MoS2, Co9S8, and Ni3S2, with the following vacuum hydrocracking performances in the order of MoS2 > Co9S8 ≫ Ni3S2, based on the same metal loading of 0.113 mmol. Among the oil-soluble Mo precursors used, Mo-hexacarbonyl, Mo-octoate, and Mo-naphthenate, Mo-octoate has an intermediate oxidation state forms the smallest particles of 5.8 nm in size and exhibits the best activity in the vacuum hydrocracking.
\nShin et al. [55] tested six newly synthesized metal precursors as catalysts for hydrocracking of vacuum residue. New group VI transition metal complexes, (LM(CO)3) (M = Mo or W, L1 = 3-phenyl-1-propyne, L2 = 4-phenyl-1-butyne, and L3 = 5-phenyl-1-pentyne) were prepared by simply stirring M(CO)3(RCN)3 (R = Me, Et) in tetrahydrofuran solution. The catalytic activity was compared to the commercially available material, Mo-octoate. LMo(CO)3 showed similar activities to Mo-octoate. Among all, L3Mo(CO)3 which had the longest alkyl chain showed a comparable result of low yield for coke and gas products [55].
\nDifferent morphologies of oil-dispersed MoS2 catalysts were obtained by a ligand stabilization method using Mo(CO)6 as a Mo precursor and trioctylphosphine oxide as a coordinating agent to identify the active site of MoS2 in the hydrocracking of vacuum residue. It was observed that the MoS2 forms a nanoscaled monolayer from 5 to 10 nm in size. The effect of the oil-dispersed MoS2 catalysts with different morphology on the slurry-phase vacuum residue hydrocracking process was investigated at 400°C and 9.5 MPa H2. The turnover frequency (TOF), activity based upon the H2 consumption rate per lateral metal number, of the dispersed MoS2 catalysts in hydrocracking shows a good correlation with the rim-site Mo dispersion of the MoS2 slabs based on the same metal loading of 0.113 mmol [56].
\nAn oil-soluble W precursor, W(CO)6, was used to prepare WS2 in situ in the hydrocracking of vacuum residue, and its activity was compared to that of oil-dispersed MoS2 prepared using the Mo precursor. Vacuum residue was treated in a batch reactor at 419°C at 9.5 MPa H2 with the metal loading of 0.113 mmol. The TOF shows a higher value for WS2 (0.709 s−1) than MoS2 (0.573 s−1) catalyst. A higher asphaltene conversion for WS2 (39.2%) than MoS2 (35.8%) was obtained. These results suggest that the WS2 catalyst exhibits a higher intrinsic activity than the MoS2 catalyst in the residue hydrocracking process. It was noted that the dispersibility of WS2 (58.0%) was found better than MoS2 (3.3%) [17].
\nLiu et al. [57] proposed a simple method for the preparation of presulfided oil-soluble MoS2 catalysts. The catalyst precursor, cetyltrimethylammonium heptamolybdate (CTATTM), was synthesized by dissolving ammonium tetrathiomolybdate in an aqueous solution containing excess cetyltrimethylammonium bromide, which could be directly dissolved in a vacuum residue. The obtained catalyst was evaluated in slurry-phase hydrocracking of vacuum residue at 410°C with an initial H2 pressure of 10 MPa for 1 h. Remarkable hydrocracking activity was observed, with a reduction of the resin content from 25.21 to 3.54 wt% and of the C7-asphaltene content from 6.82 wt.% to almost zero. With using the catalyst, the liquid yield increased from 75.03 to 96.43 wt.%, coke yield and gas yield were 0.19, and 3.38 wt.%, respectively, significantly lower than the values of 14.05 and 10.92 wt.%, respectively, obtained without using the catalyst. Additionally, with increasing Mo content, HDM conversion increased from 42.5 to 83.4 wt%, while HDS conversion increased from 21.6 to 59.2 wt%. The CTATTM precursor shows good solubility and stability in heavy oil, leading to easy formation of small MoS2 particles with stacking numbers of 1 and 2 and slab lengths of 5–11 nm. This presulfided oil-soluble MoS2 catalyst shows a great potential for further industrial applications [57].
\nHydrocracking of heavy oils differs markedly from that of light feeds owing to the fact that the catalysts used for this process are deactivated fast due to the presence of asphaltenes and metal containing molecules [58]. Restraining the deactivation of the catalysts is one of the main challenges in development of hydrocracking catalysts for heavy oil upgrading regardless of the reactor system chosen. A better understanding of the catalyst deactivation is one of the most important aspects to improve the catalytic performance in heavy oil and petroleum residue refining processes. A good commercial catalyst is known by its activity, selectivity, and stability.
\nThe main causes of loss of activity in the catalyst are due to the formation of coke and deposition of undesirable carbonaceous products, metallic compounds, and asphaltenes on the catalyst surface. In addition, the structural changes including thermally or attrition of catalyst are also responsible for the deactivation [1].
\nIn industrial catalytic processes, the loss of catalytic activity and/or selectivity over time is a major and continuing concern. The degree of catalyst deactivation is greatly influenced by the feed properties and the associated operating conditions. Generally, performance of catalysts decreases with time. In order to maintain constant product yields and/or quality, the loss of catalytic activity is compensated by periodic increases of reaction temperature [7]. Though significant costs, in the magnitude of billions of dollars annually, to industry are due to catalyst replacement and process shutdown, catalysts activity decay over time is unavoidable [59].
\nCatalyst deactivation is a complex process. Various model equations are developed in order to model the deactivation mechanisms such as coke deposition and metal accumulation. In the model, agents affecting the catalyst activity including metal content and coke precursors need to be taken into consideration. To achieve that, detailed characterizations of spent catalysts obtained at different reaction conditions, time on stream, and reactor position need to be carried out through various experiments. With the aforementioned information, a better deactivation model for heavy oil hydrocracking catalyst can be developed and further applied in reactor design, simulation, and optimization [59].
\nThe key developments in better catalyst understanding in association with particle size, pore size distribution, and activity grading have greatly improved the levels of conversion, increased run-length, and enhanced product qualities while maintaining residue fuel stability. Further catalyst performance improvement will likely come from catalyst optimization and better catalyst deactivation resistance resulting from metal poisoning and coke formation. The future challenge for a refiner will be to ensure a more efficient conversion of heavier feedstock to warrant a cleaner transportation fuel and sustainable environment for the generations to come.
\nSpecial thanks to Dr. Guan Tien Tan for his helpful comments, suggestions, and support while preparing the document.
\nHospital workers are highly susceptible to musculoskeletal disorders due to the regular lifting, positioning, and transporting of patients, combined with a fast pace work environment and a general collective temperament of putting their patients’ health before their own [1]. Upon closer review, the EP/Cath lab subset of the rural hospital workforce appears to be especially susceptible to the specific musculoskeletal disorder of low back pain. This has been attributed to the sustained forward-flexed postures they commonly maintain while working in the operating room [2], combined with a shortage of rural physicians and less community-based resources available to rural hospital staff as compared to their urban counterparts [3]. As a strategy to address this dilemma, exercise and physical activity routines, health education, and continued management support have been broadly promoted as cost-effective programs which are powerful enough to improve the health of the workforce, yet also produce a positive return on investment [4]. In theory the implementation of these low cost/low risk programs is a sound strategy based on evidence-based guidelines. The American College of Physicians strongly recommends nonpharmacologic treatments for chronic low back pain, including exercise and mindfulness-based stress reduction, because the benefits clearly outweigh the risk [5]. In practice, though, limited time and the inability to incorporate the program into everyday work routines have been found to be the two main reasons why these worksite-based fitness programs have failed to produce significant findings [6]. To overcome these barriers, hospital management must concurrently have the social, financial, and strategic investments in place which complement and support these specific wellness interventions to realize significant and lasting reductions in musculoskeletal disorders [7]. Unfortunately, the extent to which these investments have been made by hospital management, and thus perceived effective by the EP/Cath lab workforce, is unknown. Thus, the objective of this study was to determine the prevalence of low back pain in rural EP/Cath laboratories and the significance of exercise and physical activity routines, health education, and continued management support as low back pain prevention strategies in the rural EP/Cath lab community.
Those individuals who worked in the EP/Cath laboratories of two rural hospitals in the state Arkansas were eligible to participate in the study. A convenience sample design was used, and all research data were collected through the electronic transmission of a Qualtrics survey. The survey included three general sections: Nordic Musculoskeletal Questionnaire (NMQ), demographics/applicable work practice details, and low back pain prevention strategies. The first section featuring the NMQ was used to calculate the prevalence of musculoskeletal symptoms within the study population. The NMQ was developed for the analysis of musculoskeletal symptoms, [8] and has been validated and applied to a wide range of occupational groups, including nursing [9]. Additionally, the validity and reliability of the NMQ was assessed to be moderate to high and its use appropriate for epidemiological research related to musculoskeletal disorders [10]. The second section on demographics/applicable work practice assessed height, weight, gender, age, number of years worked in an EP/Cath lab setting, number of hours per week in a lead apron, and percentage of average shift spent standing in the lab. The third section on low back pain prevention strategies assessed exercise and physical activity routines, health education, and continued management support. These questions were developed through the examination of peer-reviewed journal articles, scientific posters, and government websites which promote specific behaviors or actions that had the potential to prevent or reduce low back pain [11].
A total of 45 participants were invited to participate in the study. Upon receiving IRB approval, the survey was sent to the work email address of all study participants. Data were deidentified and summarized using Microsoft Excel. Analysis showed fifteen individuals either selected they did not want to participant in the study or did not complete the survey in its entirety and thus, were omitted from the final data set. Ultimately, a total of 30 completed surveys were included in the final data set for analysis.
The first section of the survey featuring the NMQ assessed the prevalence of musculoskeletal symptoms in nine different regions of the body. The largest group, 18 (60%), stated they experienced pain in the lower back (L4 to S1) spinal level, while 12 (40%) reported no low back pain. Among the 60% of respondents who have experienced low back pain, eight (26.67%) had trouble in the last week and six (20%) were prevented from doing their normal work (at home or away from home) (Table 1).
Region of Body | Recorded “Yes” (n = 30) |
---|---|
Neck | 46.67% |
Trouble in the last 12 months | 14 |
Prevented from normal work | 1 |
Trouble in the last 7 days | 4 |
Shoulders | 40.00% |
Trouble in the last 12 months | 12 |
Prevented from normal work | 2 |
Trouble in the last 7 days | 4 |
Elbows | 13.33% |
Trouble in the last 12 months | 4 |
Prevented from normal work | 1 |
Trouble in the last 7 days | 1 |
Wrists/Hands | 13.33% |
Trouble in the last 12 months | 4 |
Prevented from normal work | 1 |
Trouble in the last 7 days | 1 |
Upper Back | 36.67% |
Trouble in the last 12 months | 11 |
Prevented from normal work | 1 |
Trouble in the last 7 days | 3 |
Lower Back | 60.00% |
Trouble in the last 12 months | 18 |
Prevented from normal work | 6 |
Trouble in the last 7 days | 8 |
Hips/Thighs | 26.67% |
Trouble in the last 12 months | 8 |
Prevented from normal work | 3 |
Trouble in the last 7 days | 2 |
Knees | 23.33% |
Trouble in the last 12 months | 7 |
Prevented from normal work | 2 |
Trouble in the last 7 days | 4 |
Feet/Ankles | 30.00% |
Trouble in the last 12 months | 9 |
Prevented from normal work | 1 |
Trouble in the last 7 days | 5 |
Per Person Mean and SD | 4.57 ± 4.03 |
Nordic musculoskeletal questionnaire number of recorded “Yes’s”.
When we compare our study to a sample of Radiologic Technologists study who similarly wear lead aprons1, the current study showed a higher overall pervasiveness of low back pain (60% to 47.62%) but less low back pain symptoms on the short-term basis (33.33% to 26.67%). Despite these discrepancies, low back pain was found to be the most prevalent musculoskeletal symptom recorded in both studies. Another significant finding in this study is the data showed an increase in the prevalence of low back pain once five years of service in an EP/Cath lab setting has been completed (58–61%) (Table 2). To provide a sense of comparison, Goldstein, et al. in (2004) likewise reported an upward trajectory in the prevalence of low back pain among Interventional Cardiologists as the number of years of service increased [12].
Total | LBP | No LBP | |
---|---|---|---|
Number | 30 | 18 | 12 |
Height (inches) | 67.30 ± 5.47 | 67.28 ± 5.54 | 67.33 ± 5.61 |
Weight (pounds) | 196.17 ± 31.79 | 194.44 ± 36.58 | 198.75 ± 24.16 |
Gender (% male) | 46.67 | 44.44 | 50.00 |
Age | 40.93 ± 11.92 | 38.67 ± 9.93 | 44.33 ± 14.20 |
Years working in EP/Cath lab setting | 9.53 ± 9.79 | 8.22 ± 6.60 | 11.50 ± 13.36 |
under 5 | 12 | 7 | 5 |
5–10 | 8 | 6 | 2 |
11–16 | 4 | 2 | 2 |
17–20 | 4 | 3 | 1 |
21 or more | 2 | 0 | 2 |
Hours per week in lead apron | 18.13 ± 10.45 | 16.17 ± 10.53 | 21.08 ± 10.02 |
% of shift spent standing in lab | 60.50 ± 24.96 | 59.44 ± 26.51 | 62.08 ± 23.50 |
Demographics/applicable work practice details stratified by the presence or absence of low Back pain (LBP).
Finally, the top two prevention strategies reported by those with low back pain were “regularly complete at least 150 minutes per week of moderate-intensity aerobic physical activity” and “if a worksite-based fitness program will be offered to you at your department, will you be interested on joining it for at least a year” (Table 3). As motivation to exercise appears to be high, interestingly no responses were recorded when asked if their worksite-based fitness program occurred on company time or if low back pain and other musculoskeletal symptoms were periodically evaluated. In addition, only one response was recorded when asked if ergonomic-related topics were discussed during team meetings. These findings suggest it is the cultural norm of the EP/Cath lab community to believe it is the personal responsibility of the employee rather than shared responsibility of the employee and hospital (EP/Cath lab) management to address the widespread low back pain present in the workforce, personified by only 36.67% of respondents reporting “hospital management believes improvements in physical conditioning will help to prolong career.”
Prevention Strategy | LBP (n = 18) | No LBP (n = 12) |
---|---|---|
Currently participate in early morning fitness program | 6 | 5 |
Yes: Includes strength training exercises | 6 | 4 |
Yes: Includes stretching exercises | 5 | 5 |
Yes: Overall do you do your fitness program regularly | 5 | 4 |
Worksite-based fitness program currently offered to dept | 4 | 5 |
Yes: Occurred on company-time | 0 | 0 |
Yes: Each class included exercises targeting the various muscle groups of the body | 4 | 5 |
Yes: Customized around dept’s specific needs, preferred communication methods, and resources available to the employees to help create a sense of ownership | 2 | 1 |
If a worksite-based fitness program will be offered to you at your department, will you be interested on joining it for at least a year | 10 | 1 |
Yes: How often to hold class (days/week) | 3 Responses: Daily 6 Responses: 3x 1 Response: 1x | 1 Response: Daily |
Yes: How long to hold class (minutes) | 2 Responses: 10–15 6 Responses: 15–20 2 Responses: Other | 1 Response: 10–15 |
Yes: Led by a faciliator or instructor | 7 | 1 |
Ergonomic-related topics discussed during team meetings | 0 | 1 |
Yes: Includes discussion on poor posture(s) | 0 | 1 |
Yes: Includes discussion on stress management | 0 | 1 |
Yes: Includes discussion on active coping strategies | 0 | 1 |
Yes: Strategies developed to overcome limited time to stretch | 0 | 1 |
Yes: Strategies developed to overcome lack of regular breaks | 0 | 1 |
Yes: Strategies developed to overcome requirement to keep the body in a sustained forward-flexed posture during surgery | 0 | 1 |
Regularly complete at least 150 minutes per week of moderate-intensity aerobic physical activity | 10 | 3 |
Regularly complete stretching exercises | 6 | 6 |
Regularly complete strength training exercises two or more days/week | 8 | 4 |
Yes: Systematically change number of sets, reps, or weight used in strength training program | 7 | 4 |
Yes: Know how to engage the deep core muscles | 7 | 4 |
Hospital management believes improvements in physical conditioning will help to prolong career | 6 | 5 |
Low back pain and other musculoskeletal symptoms periodically evaluated | 0 | 0 |
Functional Movement Screen or another validated screening tool periodically used to identify faulty movement patterns or muscular imbalances | 1 | 2 |
Prevention strategies completed by EP/Cath lab physicians, managers, and technicians stratified by the presence or absence of low Back pain (LBP).
The primary goal of this study was to illustrate the prevalence and generalized characteristics of back pain among EP and Cath laboratories in rural hospital settings. Conclusions that may be drawn from this study are the prevalence of low back pain demonstrated within this study were consistent when compared to available studies, low back pain is a common condition among EP and Cath lab employees, and several low cost/low risk preventative strategies for reducing musculoskeletal symptoms in the workforce are not currently being completed by those who participated in the study.
IntechOpen’s team of Scientific Advisors supports the publishing team by providing editorial and academic input and ensuring the highest quality output of free peer-reviewed articles. The Boards consist of independent external collaborators who assist us on a voluntary basis. Their input includes advising on new topics within their field, proposing potential expert collaborators and reviewing book publishing proposals if required. Board members are experts who cover major STEM and HSS fields. All are trusted IntechOpen collaborators and Academic Editors, ensuring that the needs of the scientific community are met.
",metaTitle:"STM Publishing and Free Peer Reviewed Articles | IntechOpen",metaDescription:"IntechOpen’s scientific advisors support the STM publishing team by offering their editorial input, ensuring a consistent output of free peer reviewed articles.",metaKeywords:null,canonicalURL:"scientific-advisors",contentRaw:'[{"type":"htmlEditorComponent","content":"\\n"}]'},components:[{type:"htmlEditorComponent",content:'
\n'}]},successStories:{items:[]},authorsAndEditors:{filterParams:{},profiles:[{id:"396",title:"Dr.",name:"Vedran",middleName:null,surname:"Kordic",slug:"vedran-kordic",fullName:"Vedran Kordic",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/396/images/7281_n.png",biography:"After obtaining his Master's degree in Mechanical Engineering he continued his education at the Vienna University of Technology where he obtained his PhD degree in 2004. He worked as a researcher at the Automation and Control Institute, Faculty of Electrical Engineering, Vienna University of Technology until 2008. His studies in robotics lead him not only to a PhD degree but also inspired him to co-found and build the International Journal of Advanced Robotic Systems - world's first Open Access journal in the field of robotics.",institutionString:null,institution:{name:"TU Wien",country:{name:"Austria"}}},{id:"441",title:"Ph.D.",name:"Jaekyu",middleName:null,surname:"Park",slug:"jaekyu-park",fullName:"Jaekyu Park",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/441/images/1881_n.jpg",biography:null,institutionString:null,institution:{name:"LG Corporation (South Korea)",country:{name:"Korea, South"}}},{id:"465",title:"Dr",name:"Christian",middleName:null,surname:"Martens",slug:"christian-martens",fullName:"Christian Martens",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"479",title:"Dr.",name:"Valentina",middleName:null,surname:"Colla",slug:"valentina-colla",fullName:"Valentina Colla",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/479/images/358_n.jpg",biography:null,institutionString:null,institution:{name:"Sant'Anna School of Advanced Studies",country:{name:"Italy"}}},{id:"494",title:"PhD",name:"Loris",middleName:null,surname:"Nanni",slug:"loris-nanni",fullName:"Loris Nanni",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/494/images/system/494.jpg",biography:"Loris Nanni received his Master Degree cum laude on June-2002 from the University of Bologna, and the April 26th 2006 he received his Ph.D. in Computer Engineering at DEIS, University of Bologna. On September, 29th 2006 he has won a post PhD fellowship from the university of Bologna (from October 2006 to October 2008), at the competitive examination he was ranked first in the industrial engineering area. He extensively served as referee for several international journals. He is author/coauthor of more than 100 research papers. He has been involved in some projects supported by MURST and European Community. His research interests include pattern recognition, bioinformatics, and biometric systems (fingerprint classification and recognition, signature verification, face recognition).",institutionString:null,institution:null},{id:"496",title:"Dr.",name:"Carlos",middleName:null,surname:"Leon",slug:"carlos-leon",fullName:"Carlos Leon",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Seville",country:{name:"Spain"}}},{id:"512",title:"Dr.",name:"Dayang",middleName:null,surname:"Jawawi",slug:"dayang-jawawi",fullName:"Dayang Jawawi",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Technology Malaysia",country:{name:"Malaysia"}}},{id:"528",title:"Dr.",name:"Kresimir",middleName:null,surname:"Delac",slug:"kresimir-delac",fullName:"Kresimir Delac",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/528/images/system/528.jpg",biography:"K. Delac received his B.Sc.E.E. degree in 2003 and is currentlypursuing a Ph.D. degree at the University of Zagreb, Faculty of Electrical Engineering andComputing. His current research interests are digital image analysis, pattern recognition andbiometrics.",institutionString:null,institution:{name:"University of Zagreb",country:{name:"Croatia"}}},{id:"557",title:"Dr.",name:"Andon",middleName:"Venelinov",surname:"Topalov",slug:"andon-topalov",fullName:"Andon Topalov",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/557/images/1927_n.jpg",biography:"Dr. Andon V. Topalov received the MSc degree in Control Engineering from the Faculty of Information Systems, Technologies, and Automation at Moscow State University of Civil Engineering (MGGU) in 1979. He then received his PhD degree in Control Engineering from the Department of Automation and Remote Control at Moscow State Mining University (MGSU), Moscow, in 1984. From 1985 to 1986, he was a Research Fellow in the Research Institute for Electronic Equipment, ZZU AD, Plovdiv, Bulgaria. In 1986, he joined the Department of Control Systems, Technical University of Sofia at the Plovdiv campus, where he is presently a Full Professor. He has held long-term visiting Professor/Scholar positions at various institutions in South Korea, Turkey, Mexico, Greece, Belgium, UK, and Germany. And he has coauthored one book and authored or coauthored more than 80 research papers in conference proceedings and journals. His current research interests are in the fields of intelligent control and robotics.",institutionString:null,institution:{name:"Technical University of Sofia",country:{name:"Bulgaria"}}},{id:"585",title:"Prof.",name:"Munir",middleName:null,surname:"Merdan",slug:"munir-merdan",fullName:"Munir Merdan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/585/images/system/585.jpg",biography:"Munir Merdan received the M.Sc. degree in mechanical engineering from the Technical University of Sarajevo, Bosnia and Herzegovina, in 2001, and the Ph.D. degree in electrical engineering from the Vienna University of Technology, Vienna, Austria, in 2009.Since 2005, he has been at the Automation and Control Institute, Vienna University of Technology, where he is currently a Senior Researcher. His research interests include the application of agent technology for achieving agile control in the manufacturing environment.",institutionString:null,institution:null},{id:"605",title:"Prof",name:"Dil",middleName:null,surname:"Hussain",slug:"dil-hussain",fullName:"Dil Hussain",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/605/images/system/605.jpg",biography:"Dr. Dil Muhammad Akbar Hussain is a professor of Electronics Engineering & Computer Science at the Department of Energy Technology, Aalborg University Denmark. Professor Akbar has a Master degree in Digital Electronics from Govt. College University, Lahore Pakistan and a P-hD degree in Control Engineering from the School of Engineering and Applied Sciences, University of Sussex United Kingdom. Aalborg University has Two Satellite Campuses, one in Copenhagen (Aalborg University Copenhagen) and the other in Esbjerg (Aalborg University Esbjerg).\n· He is a member of prestigious IEEE (Institute of Electrical and Electronics Engineers), and IAENG (International Association of Engineers) organizations. \n· He is the chief Editor of the Journal of Software Engineering.\n· He is the member of the Editorial Board of International Journal of Computer Science and Software Technology (IJCSST) and International Journal of Computer Engineering and Information Technology. \n· He is also the Editor of Communication in Computer and Information Science CCIS-20 by Springer.\n· Reviewer For Many Conferences\nHe is the lead person in making collaboration agreements between Aalborg University and many universities of Pakistan, for which the MOU’s (Memorandum of Understanding) have been signed.\nProfessor Akbar is working in Academia since 1990, he started his career as a Lab demonstrator/TA at the University of Sussex. After finishing his P. hD degree in 1992, he served in the Industry as a Scientific Officer and continued his academic career as a visiting scholar for a number of educational institutions. In 1996 he joined National University of Science & Technology Pakistan (NUST) as an Associate Professor; NUST is one of the top few universities in Pakistan. In 1999 he joined an International Company Lineo Inc, Canada as Manager Compiler Group, where he headed the group for developing Compiler Tool Chain and Porting of Operating Systems for the BLACKfin processor. The processor development was a joint venture by Intel and Analog Devices. In 2002 Lineo Inc., was taken over by another company, so he joined Aalborg University Denmark as an Assistant Professor.\nProfessor Akbar has truly a multi-disciplined career and he continued his legacy and making progress in many areas of his interests both in teaching and research. He has contributed in stochastic estimation of control area especially, in the Multiple Target Tracking and Interactive Multiple Model (IMM) research, Ball & Beam Control Problem, Robotics, Levitation Control. He has contributed in developing Algorithms for Fingerprint Matching, Computer Vision and Face Recognition. He has been supervising Pattern Recognition, Formal Languages and Distributed Processing projects for several years. He has reviewed many books on Management, Computer Science. Currently, he is an active and permanent reviewer for many international conferences and symposia and the program committee member for many international conferences.\nIn teaching he has taught the core computer science subjects like, Digital Design, Real Time Embedded System Programming, Operating Systems, Software Engineering, Data Structures, Databases, Compiler Construction. In the Engineering side, Digital Signal Processing, Computer Architecture, Electronics Devices, Digital Filtering and Engineering Management.\nApart from his Academic Interest and activities he loves sport especially, Cricket, Football, Snooker and Squash. He plays cricket for Esbjerg city in the second division team as an opener wicket keeper batsman. He is a very good player of squash but has not played squash since his arrival in Denmark.",institutionString:null,institution:null},{id:"611",title:"Prof.",name:"T",middleName:null,surname:"Nagarajan",slug:"t-nagarajan",fullName:"T Nagarajan",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Universiti Teknologi Petronas",country:{name:"Malaysia"}}}],filtersByRegion:[{group:"region",caption:"North America",value:1,count:6675},{group:"region",caption:"Middle and South America",value:2,count:5955},{group:"region",caption:"Africa",value:3,count:2459},{group:"region",caption:"Asia",value:4,count:12718},{group:"region",caption:"Australia and Oceania",value:5,count:1017},{group:"region",caption:"Europe",value:6,count:17720}],offset:12,limit:12,total:134177},chapterEmbeded:{data:{}},editorApplication:{success:null,errors:{}},ofsBooks:{filterParams:{topicId:"19"},books:[{type:"book",id:"11680",title:"Immune Checkpoint Inhibitors - New Insights and Recent Progress",subtitle:null,isOpenForSubmission:!0,hash:"65dc94eb0a8dd733522f67d95b2c2d48",slug:null,bookSignature:"Dr. Afsheen Raza",coverURL:"https://cdn.intechopen.com/books/images_new/11680.jpg",editedByType:null,editors:[{id:"339296",title:"Dr.",name:"Afsheen",surname:"Raza",slug:"afsheen-raza",fullName:"Afsheen Raza"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11688",title:"Advances in Drug Delivery Methods",subtitle:null,isOpenForSubmission:!0,hash:"b237999737fb375b4f629ab01a498a9f",slug:null,bookSignature:"Prof. Bhupendra Gopalbhai Prajapati",coverURL:"https://cdn.intechopen.com/books/images_new/11688.jpg",editedByType:null,editors:[{id:"340226",title:"Prof.",name:"Bhupendra",surname:"Prajapati",slug:"bhupendra-prajapati",fullName:"Bhupendra Prajapati"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11690",title:"COVID-19 Drug Development - Recent Advances, New Perspectives, and Applications",subtitle:null,isOpenForSubmission:!0,hash:"f8092a491f68ca0b63cc6d40936a010a",slug:null,bookSignature:"Dr. Arli Aditya Parikesit",coverURL:"https://cdn.intechopen.com/books/images_new/11690.jpg",editedByType:null,editors:[{id:"72288",title:"Dr.",name:"Arli Aditya",surname:"Parikesit",slug:"arli-aditya-parikesit",fullName:"Arli Aditya Parikesit"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11812",title:"New Insights Into Pharmacodynamics",subtitle:null,isOpenForSubmission:!0,hash:"b889e24b3132aa437b6745db36fffe9b",slug:null,bookSignature:"Prof. Mahmoud Ahmed Mansour",coverURL:"https://cdn.intechopen.com/books/images_new/11812.jpg",editedByType:null,editors:[{id:"224662",title:"Prof.",name:"Mahmoud Ahmed",surname:"Mansour",slug:"mahmoud-ahmed-mansour",fullName:"Mahmoud Ahmed Mansour"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11813",title:"RNA Therapeutics - History, Design, Manufacturing, and Applications",subtitle:null,isOpenForSubmission:!0,hash:"fbffd7b2f97a65ffb0901de38a65bed0",slug:null,bookSignature:"Prof. Irina Vlasova-St. Louis",coverURL:"https://cdn.intechopen.com/books/images_new/11813.jpg",editedByType:null,editors:[{id:"211159",title:"Prof.",name:"Irina",surname:"Vlasova-St. Louis",slug:"irina-vlasova-st.-louis",fullName:"Irina Vlasova-St. Louis"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"12205",title:"Photodynamic Therapy",subtitle:null,isOpenForSubmission:!0,hash:"8099dd8f660b401e5ecfa85ce3f0df81",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/12205.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"12206",title:"Antibiotic Resistance - New Insights",subtitle:null,isOpenForSubmission:!0,hash:"708d9c997d91bdbe75c55cb5d9f7b526",slug:null,bookSignature:"Dr. Ghulam Mustafa",coverURL:"https://cdn.intechopen.com/books/images_new/12206.jpg",editedByType:null,editors:[{id:"298756",title:"Dr.",name:"Ghulam",surname:"Mustafa",slug:"ghulam-mustafa",fullName:"Ghulam Mustafa"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"12207",title:"Statins",subtitle:null,isOpenForSubmission:!0,hash:"245ddb277df310de302579b803b715b8",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/12207.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"12208",title:"Metformin - A Prospective Alternative for the Treatment of Chronic Diseases",subtitle:null,isOpenForSubmission:!0,hash:"aa4b8aac3f44ba3ab334530c5d5646ea",slug:null,bookSignature:"Prof. Farid A. Badria",coverURL:"https://cdn.intechopen.com/books/images_new/12208.jpg",editedByType:null,editors:[{id:"41865",title:"Prof.",name:"Farid A.",surname:"Badria",slug:"farid-a.-badria",fullName:"Farid A. Badria"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"12209",title:"Vitamin B Complex",subtitle:null,isOpenForSubmission:!0,hash:"56e8be78a5a1aed62dbc6e8f3c1371f8",slug:null,bookSignature:"Prof. Juber Akhtar, Dr. Mohammad Ahmad, Dr. Mohammad Irfan Khan and Dr. Badruddeen",coverURL:"https://cdn.intechopen.com/books/images_new/12209.jpg",editedByType:null,editors:[{id:"345595",title:"Prof.",name:"Juber",surname:"Akhtar",slug:"juber-akhtar",fullName:"Juber Akhtar"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"12212",title:"Hypoxia",subtitle:null,isOpenForSubmission:!0,hash:"c7561177210ce5982b54d46a48666012",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/12212.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"12315",title:"Cosmetic Products and Industry",subtitle:null,isOpenForSubmission:!0,hash:"4730ab11e05d70d04ea88d87983a5cef",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/12315.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],filtersByTopic:[{group:"topic",caption:"Agricultural and Biological Sciences",value:5,count:38},{group:"topic",caption:"Biochemistry, Genetics and Molecular Biology",value:6,count:12},{group:"topic",caption:"Business, Management and Economics",value:7,count:7},{group:"topic",caption:"Chemistry",value:8,count:22},{group:"topic",caption:"Computer and Information Science",value:9,count:23},{group:"topic",caption:"Earth and Planetary Sciences",value:10,count:15},{group:"topic",caption:"Engineering",value:11,count:65},{group:"topic",caption:"Environmental Sciences",value:12,count:10},{group:"topic",caption:"Immunology and Microbiology",value:13,count:15},{group:"topic",caption:"Materials Science",value:14,count:24},{group:"topic",caption:"Mathematics",value:15,count:11},{group:"topic",caption:"Medicine",value:16,count:114},{group:"topic",caption:"Nanotechnology and Nanomaterials",value:17,count:6},{group:"topic",caption:"Neuroscience",value:18,count:4},{group:"topic",caption:"Pharmacology, Toxicology and Pharmaceutical Science",value:19,count:9},{group:"topic",caption:"Physics",value:20,count:9},{group:"topic",caption:"Psychology",value:21,count:10},{group:"topic",caption:"Robotics",value:22,count:2},{group:"topic",caption:"Social Sciences",value:23,count:9},{group:"topic",caption:"Veterinary Medicine and Science",value:25,count:4}],offset:12,limit:12,total:15},popularBooks:{featuredBooks:[{type:"book",id:"10858",title:"MOOC (Massive Open Online Courses)",subtitle:null,isOpenForSubmission:!1,hash:"d32f86793bc72dde32532f509b1ec5b0",slug:"mooc-massive-open-online-courses-",bookSignature:"Dragan Cvetković",coverURL:"https://cdn.intechopen.com/books/images_new/10858.jpg",editors:[{id:"101330",title:"Dr.",name:"Dragan",middleName:"Mladen",surname:"Cvetković",slug:"dragan-cvetkovic",fullName:"Dragan Cvetković"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10195",title:"Serotonin and the CNS",subtitle:"New Developments in Pharmacology and Therapeutics",isOpenForSubmission:!1,hash:"7ed9d96da98233a885bd2869a8056c36",slug:"serotonin-and-the-cns-new-developments-in-pharmacology-and-therapeutics",bookSignature:"Berend Olivier",coverURL:"https://cdn.intechopen.com/books/images_new/10195.jpg",editors:[{id:"71579",title:"Prof.",name:"Berend",middleName:null,surname:"Olivier",slug:"berend-olivier",fullName:"Berend Olivier"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10755",title:"Corporate Governance",subtitle:"Recent Advances and Perspectives",isOpenForSubmission:!1,hash:"ffe06d1d5c4bf0fc2e63511825fe1257",slug:"corporate-governance-recent-advances-and-perspectives",bookSignature:"Okechukwu Lawrence Emeagwali and Feyza Bhatti",coverURL:"https://cdn.intechopen.com/books/images_new/10755.jpg",editors:[{id:"196317",title:"Associate Prof.",name:"Okechukwu Lawrence",middleName:null,surname:"Emeagwali",slug:"okechukwu-lawrence-emeagwali",fullName:"Okechukwu Lawrence Emeagwali"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11120",title:"Environmental Impact and Remediation of Heavy Metals",subtitle:null,isOpenForSubmission:!1,hash:"9e77514288e7394f1e6cd13481af3509",slug:"environmental-impact-and-remediation-of-heavy-metals",bookSignature:"Hosam M. Saleh and Amal I. Hassan",coverURL:"https://cdn.intechopen.com/books/images_new/11120.jpg",editors:[{id:"144691",title:"Prof.",name:"Hosam M.",middleName:null,surname:"Saleh",slug:"hosam-m.-saleh",fullName:"Hosam M. Saleh"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10901",title:"Grapes and Wine",subtitle:null,isOpenForSubmission:!1,hash:"5d7f2aa74874444bc6986e613ccebd7c",slug:"grapes-and-wine",bookSignature:"Antonio Morata, Iris Loira and Carmen González",coverURL:"https://cdn.intechopen.com/books/images_new/10901.jpg",editors:[{id:"180952",title:"Prof.",name:"Antonio",middleName:null,surname:"Morata",slug:"antonio-morata",fullName:"Antonio Morata"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11080",title:"Engineering Principles",subtitle:"Welding and Residual Stresses",isOpenForSubmission:!1,hash:"6c07a13a113bce94174b40096f30fb5e",slug:"engineering-principles-welding-and-residual-stresses",bookSignature:"Kavian Omar Cooke and Ronaldo Câmara Cozza",coverURL:"https://cdn.intechopen.com/books/images_new/11080.jpg",editors:[{id:"138778",title:"Dr.",name:"Kavian",middleName:"Omar",surname:"Cooke",slug:"kavian-cooke",fullName:"Kavian Cooke"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11332",title:"Essential Oils",subtitle:"Advances in Extractions and Biological Applications",isOpenForSubmission:!1,hash:"742e6cae3a35686f975edc8d7f9afa94",slug:"essential-oils-advances-in-extractions-and-biological-applications",bookSignature:"Mozaniel Santana de Oliveira and Eloisa Helena de Aguiar Andrade",coverURL:"https://cdn.intechopen.com/books/images_new/11332.jpg",editors:[{id:"195290",title:"Ph.D.",name:"Mozaniel",middleName:null,surname:"Santana De Oliveira",slug:"mozaniel-santana-de-oliveira",fullName:"Mozaniel Santana De Oliveira"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11029",title:"Hepatitis B",subtitle:null,isOpenForSubmission:!1,hash:"609701f502efc3538c112ff47a2c2119",slug:"hepatitis-b",bookSignature:"Luis Rodrigo",coverURL:"https://cdn.intechopen.com/books/images_new/11029.jpg",editors:[{id:"73208",title:"Prof.",name:"Luis",middleName:null,surname:"Rodrigo",slug:"luis-rodrigo",fullName:"Luis Rodrigo"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9537",title:"Human Rights in the Contemporary World",subtitle:null,isOpenForSubmission:!1,hash:"54f05b93812fd434f3962956d6413a6b",slug:"human-rights-in-the-contemporary-world",bookSignature:"Trudy Corrigan",coverURL:"https://cdn.intechopen.com/books/images_new/9537.jpg",editors:[{id:"197557",title:"Dr.",name:"Trudy",middleName:null,surname:"Corrigan",slug:"trudy-corrigan",fullName:"Trudy Corrigan"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11371",title:"Cerebral Circulation",subtitle:"Updates on Models, Diagnostics and Treatments of Related Diseases",isOpenForSubmission:!1,hash:"e2d3335445d2852d0b906bb9750e939f",slug:"cerebral-circulation-updates-on-models-diagnostics-and-treatments-of-related-diseases",bookSignature:"Alba Scerrati, Luca Ricciardi and Flavia Dones",coverURL:"https://cdn.intechopen.com/books/images_new/11371.jpg",editors:[{id:"182614",title:"Dr.",name:"Alba",middleName:null,surname:"Scerrati",slug:"alba-scerrati",fullName:"Alba Scerrati"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11012",title:"Radiopharmaceuticals",subtitle:"Current Research for Better Diagnosis and Therapy",isOpenForSubmission:!1,hash:"f9046d6f96148b285e776f384991120d",slug:"radiopharmaceuticals-current-research-for-better-diagnosis-and-therapy",bookSignature:"Farid A. Badria",coverURL:"https://cdn.intechopen.com/books/images_new/11012.jpg",editors:[{id:"41865",title:"Prof.",name:"Farid A.",middleName:null,surname:"Badria",slug:"farid-a.-badria",fullName:"Farid A. Badria"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9974",title:"E-Learning and Digital Education in the Twenty-First Century",subtitle:null,isOpenForSubmission:!1,hash:"88b58d66e975df20425fc1dfd22d53aa",slug:"e-learning-and-digital-education-in-the-twenty-first-century",bookSignature:"M. Mahruf C. Shohel",coverURL:"https://cdn.intechopen.com/books/images_new/9974.jpg",editors:[{id:"94099",title:"Dr.",name:"M. Mahruf C.",middleName:null,surname:"Shohel",slug:"m.-mahruf-c.-shohel",fullName:"M. Mahruf C. Shohel"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}}],offset:12,limit:12,total:4431},hotBookTopics:{hotBooks:[],offset:0,limit:12,total:null},publish:{},publishingProposal:{success:null,errors:{}},books:{featuredBooks:[{type:"book",id:"10858",title:"MOOC (Massive Open Online Courses)",subtitle:null,isOpenForSubmission:!1,hash:"d32f86793bc72dde32532f509b1ec5b0",slug:"mooc-massive-open-online-courses-",bookSignature:"Dragan Cvetković",coverURL:"https://cdn.intechopen.com/books/images_new/10858.jpg",publishedDate:"June 23rd 2022",numberOfDownloads:1677,editors:[{id:"101330",title:"Dr.",name:"Dragan",middleName:"Mladen",surname:"Cvetković",slug:"dragan-cvetkovic",fullName:"Dragan Cvetković"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10195",title:"Serotonin and the CNS",subtitle:"New Developments in Pharmacology and Therapeutics",isOpenForSubmission:!1,hash:"7ed9d96da98233a885bd2869a8056c36",slug:"serotonin-and-the-cns-new-developments-in-pharmacology-and-therapeutics",bookSignature:"Berend Olivier",coverURL:"https://cdn.intechopen.com/books/images_new/10195.jpg",publishedDate:"June 23rd 2022",numberOfDownloads:1337,editors:[{id:"71579",title:"Prof.",name:"Berend",middleName:null,surname:"Olivier",slug:"berend-olivier",fullName:"Berend Olivier"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10755",title:"Corporate Governance",subtitle:"Recent Advances and Perspectives",isOpenForSubmission:!1,hash:"ffe06d1d5c4bf0fc2e63511825fe1257",slug:"corporate-governance-recent-advances-and-perspectives",bookSignature:"Okechukwu Lawrence Emeagwali and Feyza Bhatti",coverURL:"https://cdn.intechopen.com/books/images_new/10755.jpg",publishedDate:"June 23rd 2022",numberOfDownloads:1309,editors:[{id:"196317",title:"Associate Prof.",name:"Okechukwu Lawrence",middleName:null,surname:"Emeagwali",slug:"okechukwu-lawrence-emeagwali",fullName:"Okechukwu Lawrence Emeagwali"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11120",title:"Environmental Impact and Remediation of Heavy Metals",subtitle:null,isOpenForSubmission:!1,hash:"9e77514288e7394f1e6cd13481af3509",slug:"environmental-impact-and-remediation-of-heavy-metals",bookSignature:"Hosam M. Saleh and Amal I. Hassan",coverURL:"https://cdn.intechopen.com/books/images_new/11120.jpg",publishedDate:"June 23rd 2022",numberOfDownloads:847,editors:[{id:"144691",title:"Prof.",name:"Hosam M.",middleName:null,surname:"Saleh",slug:"hosam-m.-saleh",fullName:"Hosam M. Saleh"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10901",title:"Grapes and Wine",subtitle:null,isOpenForSubmission:!1,hash:"5d7f2aa74874444bc6986e613ccebd7c",slug:"grapes-and-wine",bookSignature:"Antonio Morata, Iris Loira and Carmen González",coverURL:"https://cdn.intechopen.com/books/images_new/10901.jpg",publishedDate:"June 15th 2022",numberOfDownloads:2273,editors:[{id:"180952",title:"Prof.",name:"Antonio",middleName:null,surname:"Morata",slug:"antonio-morata",fullName:"Antonio Morata"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11080",title:"Engineering Principles",subtitle:"Welding and Residual Stresses",isOpenForSubmission:!1,hash:"6c07a13a113bce94174b40096f30fb5e",slug:"engineering-principles-welding-and-residual-stresses",bookSignature:"Kavian Omar Cooke and Ronaldo Câmara Cozza",coverURL:"https://cdn.intechopen.com/books/images_new/11080.jpg",publishedDate:"June 23rd 2022",numberOfDownloads:591,editors:[{id:"138778",title:"Dr.",name:"Kavian",middleName:"Omar",surname:"Cooke",slug:"kavian-cooke",fullName:"Kavian Cooke"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11332",title:"Essential Oils",subtitle:"Advances in Extractions and Biological Applications",isOpenForSubmission:!1,hash:"742e6cae3a35686f975edc8d7f9afa94",slug:"essential-oils-advances-in-extractions-and-biological-applications",bookSignature:"Mozaniel Santana de Oliveira and Eloisa Helena de Aguiar Andrade",coverURL:"https://cdn.intechopen.com/books/images_new/11332.jpg",publishedDate:"June 23rd 2022",numberOfDownloads:515,editors:[{id:"195290",title:"Ph.D.",name:"Mozaniel",middleName:null,surname:"Santana De Oliveira",slug:"mozaniel-santana-de-oliveira",fullName:"Mozaniel Santana De Oliveira"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11029",title:"Hepatitis B",subtitle:null,isOpenForSubmission:!1,hash:"609701f502efc3538c112ff47a2c2119",slug:"hepatitis-b",bookSignature:"Luis Rodrigo",coverURL:"https://cdn.intechopen.com/books/images_new/11029.jpg",publishedDate:"June 23rd 2022",numberOfDownloads:413,editors:[{id:"73208",title:"Prof.",name:"Luis",middleName:null,surname:"Rodrigo",slug:"luis-rodrigo",fullName:"Luis Rodrigo"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9537",title:"Human Rights in the Contemporary World",subtitle:null,isOpenForSubmission:!1,hash:"54f05b93812fd434f3962956d6413a6b",slug:"human-rights-in-the-contemporary-world",bookSignature:"Trudy Corrigan",coverURL:"https://cdn.intechopen.com/books/images_new/9537.jpg",publishedDate:"June 8th 2022",numberOfDownloads:2194,editors:[{id:"197557",title:"Dr.",name:"Trudy",middleName:null,surname:"Corrigan",slug:"trudy-corrigan",fullName:"Trudy Corrigan"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11371",title:"Cerebral Circulation",subtitle:"Updates on Models, Diagnostics and Treatments of Related Diseases",isOpenForSubmission:!1,hash:"e2d3335445d2852d0b906bb9750e939f",slug:"cerebral-circulation-updates-on-models-diagnostics-and-treatments-of-related-diseases",bookSignature:"Alba Scerrati, Luca Ricciardi and Flavia Dones",coverURL:"https://cdn.intechopen.com/books/images_new/11371.jpg",publishedDate:"June 23rd 2022",numberOfDownloads:341,editors:[{id:"182614",title:"Dr.",name:"Alba",middleName:null,surname:"Scerrati",slug:"alba-scerrati",fullName:"Alba Scerrati"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}}],latestBooks:[{type:"book",id:"11043",title:"Endometriosis",subtitle:"Recent Advances, New Perspectives and Treatments",isOpenForSubmission:!1,hash:"7baf1c70b11d41400bb9302ae9411ca4",slug:"endometriosis-recent-advances-new-perspectives-and-treatments",bookSignature:"Giovana Ap. Gonçalves",coverURL:"https://cdn.intechopen.com/books/images_new/11043.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"185930",title:"Associate Prof.",name:"Giovana",middleName:null,surname:"Gonçalves",slug:"giovana-goncalves",fullName:"Giovana Gonçalves"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10536",title:"Campylobacter",subtitle:null,isOpenForSubmission:!1,hash:"c4b132b741dd0a2ed539b824ab63965f",slug:"campylobacter",bookSignature:"Guillermo Tellez-Isaias and Saeed El-Ashram",coverURL:"https://cdn.intechopen.com/books/images_new/10536.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"73465",title:"Dr.",name:"Guillermo",middleName:null,surname:"Téllez",slug:"guillermo-tellez",fullName:"Guillermo Téllez"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10798",title:"Starch",subtitle:"Evolution and Recent Advances",isOpenForSubmission:!1,hash:"f197f6062c1574a9a90e50a369271bcf",slug:"starch-evolution-and-recent-advances",bookSignature:"Martins Ochubiojo Emeje",coverURL:"https://cdn.intechopen.com/books/images_new/10798.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"94311",title:"Prof.",name:"Martins",middleName:"Ochubiojo",surname:"Ochubiojo Emeje",slug:"martins-ochubiojo-emeje",fullName:"Martins Ochubiojo Emeje"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11083",title:"Hazardous Waste Management",subtitle:null,isOpenForSubmission:!1,hash:"d553bd4f6f1c4b115ca69bd19faac7dc",slug:"hazardous-waste-management",bookSignature:"Rajesh Banu Jeyakumar, Kavitha Sankarapandian and Yukesh Kannah Ravi",coverURL:"https://cdn.intechopen.com/books/images_new/11083.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"218539",title:"Dr.",name:"Rajesh Banu",middleName:null,surname:"Jeyakumar",slug:"rajesh-banu-jeyakumar",fullName:"Rajesh Banu Jeyakumar"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10848",title:"Tribology of Machine Elements",subtitle:"Fundamentals and Applications",isOpenForSubmission:!1,hash:"3c4ca4c4692ca8d4fa749b4ae81ec1fa",slug:"tribology-of-machine-elements-fundamentals-and-applications",bookSignature:"Giuseppe Pintaude, Tiago Cousseau and Anna Rudawska",coverURL:"https://cdn.intechopen.com/books/images_new/10848.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"18347",title:"Prof.",name:"Giuseppe",middleName:null,surname:"Pintaude",slug:"giuseppe-pintaude",fullName:"Giuseppe Pintaude"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10856",title:"Crude Oil",subtitle:"New Technologies and Recent Approaches",isOpenForSubmission:!1,hash:"8d0a7ca35b3de95b295dc4eab39a087e",slug:"crude-oil-new-technologies-and-recent-approaches",bookSignature:"Manar Elsayed Abdel-Raouf and Mohamed Hasan El-Keshawy",coverURL:"https://cdn.intechopen.com/books/images_new/10856.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"102626",title:"Prof.",name:"Manar",middleName:null,surname:"Elsayed Abdel-Raouf",slug:"manar-elsayed-abdel-raouf",fullName:"Manar Elsayed Abdel-Raouf"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9625",title:"Spinocerebellar Ataxia",subtitle:"Concepts, Particularities and Generalities",isOpenForSubmission:!1,hash:"365a7025fd46eb45de2549bdd9d50b98",slug:"spinocerebellar-ataxia-concepts-particularities-and-generalities",bookSignature:"Patricia Bozzetto Ambrosi",coverURL:"https://cdn.intechopen.com/books/images_new/9625.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"221787",title:"Dr.",name:"Patricia",middleName:null,surname:"Bozzetto Ambrosi",slug:"patricia-bozzetto-ambrosi",fullName:"Patricia Bozzetto Ambrosi"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10905",title:"Plant Defense Mechanisms",subtitle:null,isOpenForSubmission:!1,hash:"84ad5b27dde5f01dc76087d0fd6fa834",slug:"plant-defense-mechanisms",bookSignature:"Josphert Ngui Kimatu",coverURL:"https://cdn.intechopen.com/books/images_new/10905.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"224171",title:"Prof.",name:"Josphert N.",middleName:null,surname:"Kimatu",slug:"josphert-n.-kimatu",fullName:"Josphert N. Kimatu"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10686",title:"Natural Gas",subtitle:"New Perspectives and Future Developments",isOpenForSubmission:!1,hash:"581763788a6a59e653a9d1d9b5a42d79",slug:"natural-gas-new-perspectives-and-future-developments",bookSignature:"Maryam Takht Ravanchi",coverURL:"https://cdn.intechopen.com/books/images_new/10686.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"2416",title:"Dr.",name:"Maryam",middleName:null,surname:"Takht Ravanchi",slug:"maryam-takht-ravanchi",fullName:"Maryam Takht Ravanchi"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10988",title:"Railway Transport Planning and Manageme",subtitle:null,isOpenForSubmission:!1,hash:"5cb54cc53caedad9ec78372563c82e2c",slug:"railway-transport-planning-and-management",bookSignature:"Stefano de Luca, Roberta Di Pace and Chiara Fiori",coverURL:"https://cdn.intechopen.com/books/images_new/10988.jpg",editedByType:"Edited by",publishedDate:"June 28th 2022",editors:[{id:"271061",title:"Prof.",name:"Stefano",middleName:null,surname:"de Luca",slug:"stefano-de-luca",fullName:"Stefano de Luca"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}]},subject:{topic:{id:"366",title:"Mycetology",slug:"mycetology",parent:{id:"41",title:"Plant Biology",slug:"agricultural-and-biological-sciences-plant-biology"},numberOfBooks:4,numberOfSeries:0,numberOfAuthorsAndEditors:116,numberOfWosCitations:325,numberOfCrossrefCitations:171,numberOfDimensionsCitations:403,videoUrl:null,fallbackUrl:null,description:null},booksByTopicFilter:{topicId:"366",sort:"-publishedDate",limit:12,offset:0},booksByTopicCollection:[{type:"book",id:"9463",title:"An Introduction to Mushroom",subtitle:null,isOpenForSubmission:!1,hash:"989e23dafb2b12c71acfe79ce04c3c2b",slug:"an-introduction-to-mushroom",bookSignature:"Ajit Kumar Passari and Sergio Sánchez",coverURL:"https://cdn.intechopen.com/books/images_new/9463.jpg",editedByType:"Edited by",editors:[{id:"304710",title:"Dr.",name:"Ajit",middleName:null,surname:"Kumar Passari",slug:"ajit-kumar-passari",fullName:"Ajit Kumar Passari"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"8081",title:"Trichoderma",subtitle:"The Most Widely Used Fungicide",isOpenForSubmission:!1,hash:"fb120bd787a35aeeb72997edc44d0c5d",slug:"trichoderma-the-most-widely-used-fungicide",bookSignature:"Mohammad Manjur Shah, Umar Sharif and Tijjani Rufai Buhari",coverURL:"https://cdn.intechopen.com/books/images_new/8081.jpg",editedByType:"Edited by",editors:[{id:"94128",title:"Dr.",name:"Mohammad Manjur",middleName:null,surname:"Shah",slug:"mohammad-manjur-shah",fullName:"Mohammad Manjur Shah"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"6923",title:"Candida Albicans",subtitle:null,isOpenForSubmission:!1,hash:"b037c09c5e2980ef09b650b87fabb668",slug:"candida-albicans",bookSignature:"Doblin Sandai",coverURL:"https://cdn.intechopen.com/books/images_new/6923.jpg",editedByType:"Edited by",editors:[{id:"179627",title:"Dr.",name:"Doblin",middleName:null,surname:"Sandai",slug:"doblin-sandai",fullName:"Doblin Sandai"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"22",title:"Fungicides",subtitle:null,isOpenForSubmission:!1,hash:null,slug:"fungicides",bookSignature:"Odile Carisse",coverURL:"https://cdn.intechopen.com/books/images_new/22.jpg",editedByType:"Edited by",editors:[{id:"14447",title:"Dr.",name:"Odile",middleName:null,surname:"Carisse",slug:"odile-carisse",fullName:"Odile Carisse"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],booksByTopicTotal:4,seriesByTopicCollection:[],seriesByTopicTotal:0,mostCitedChapters:[{id:"12733",doi:"10.5772/13032",title:"Environmental Risks of Fungicides Used in Horticultural Production Systems",slug:"environmental-risks-of-fungicides-used-in-horticultural-production-systems",totalDownloads:8350,totalCrossrefCites:33,totalDimensionsCites:87,abstract:null,book:{id:"22",slug:"fungicides",title:"Fungicides",fullTitle:"Fungicides"},signatures:"Adam Wightwick, Robert Walters, Graeme Allinson, Suzanne Reichman and Neal Menzies",authors:[{id:"13708",title:"BSc.",name:"Adam",middleName:"Mark",surname:"Wightwick",slug:"adam-wightwick",fullName:"Adam Wightwick"},{id:"14050",title:"Dr.",name:"Suzanne",middleName:null,surname:"Reichman",slug:"suzanne-reichman",fullName:"Suzanne Reichman"},{id:"14051",title:"Dr.",name:"Graeme",middleName:null,surname:"Allinson",slug:"graeme-allinson",fullName:"Graeme Allinson"},{id:"14052",title:"Prof.",name:"Neal",middleName:null,surname:"Menzies",slug:"neal-menzies",fullName:"Neal Menzies"},{id:"23793",title:"Mr.",name:"Robert",middleName:null,surname:"Walters",slug:"robert-walters",fullName:"Robert Walters"}]},{id:"12393",doi:"10.5772/10482",title:"Propiconazole Toxicity on the Non-Target Organism, the Arbuscular Mycorrhizal Fungus, Glomus irregulare",slug:"propiconazole-toxicity-on-the-non-target-organism-the-arbuscular-mycorrhizal-fungus-glomus-sp-",totalDownloads:4155,totalCrossrefCites:6,totalDimensionsCites:21,abstract:null,book:{id:"22",slug:"fungicides",title:"Fungicides",fullTitle:"Fungicides"},signatures:"Maryline Calonne, Joël Fontaine, Djouher Debiane, Frédéric Laruelle, Anne Grandmougin-Ferjani and Anissa Lounès-Hadj Sahraoui",authors:null},{id:"12394",doi:"10.5772/12959",title:"Fungicides and Their Effects on Animals",slug:"fungicides-and-their-effects-on-animals",totalDownloads:16740,totalCrossrefCites:3,totalDimensionsCites:21,abstract:null,book:{id:"22",slug:"fungicides",title:"Fungicides",fullTitle:"Fungicides"},signatures:"Hasan H. Oruc",authors:[{id:"13562",title:"Dr.",name:"Hasan H.",middleName:null,surname:"Oruc",slug:"hasan-h.-oruc",fullName:"Hasan H. Oruc"}]},{id:"12383",doi:"10.5772/13233",title:"Fungicides for Wood Protection - World Viewpoint and Evaluation/Testing in Slovakia",slug:"fungicides-for-wood-protection-world-viewpoint-and-evaluation-testing-in-slovakia",totalDownloads:8531,totalCrossrefCites:3,totalDimensionsCites:21,abstract:null,book:{id:"22",slug:"fungicides",title:"Fungicides",fullTitle:"Fungicides"},signatures:"Ladislav Reinprecht",authors:[{id:"14159",title:"Dr.",name:"Ladislav",middleName:null,surname:"Reinprecht",slug:"ladislav-reinprecht",fullName:"Ladislav Reinprecht"}]},{id:"12388",doi:"10.5772/13205",title:"The QoI Fungicides, the Rise and Fall of a Successful Class of Agricultural Fungicides",slug:"the-qoi-fungicides-the-rise-and-fall-of-a-successful-class-of-agricultural-fungicides",totalDownloads:6430,totalCrossrefCites:14,totalDimensionsCites:21,abstract:null,book:{id:"22",slug:"fungicides",title:"Fungicides",fullTitle:"Fungicides"},signatures:"Dolores Fernández-ortuño, Juan A. Torés, Antonio De Vicente and Alejandro Pérez-garcía",authors:[{id:"14104",title:"Dr.",name:"Alejandro",middleName:null,surname:"Pérez-García",slug:"alejandro-perez-garcia",fullName:"Alejandro Pérez-García"},{id:"15417",title:"Prof.",name:"Antonio",middleName:null,surname:"de Vicente",slug:"antonio-de-vicente",fullName:"Antonio de Vicente"},{id:"15419",title:"Dr.",name:"Juan A.",middleName:null,surname:"Torés",slug:"juan-a.-tores",fullName:"Juan A. Torés"},{id:"15420",title:"Dr.",name:"Dolores",middleName:null,surname:"Fernández-Ortuño",slug:"dolores-fernandez-ortuno",fullName:"Dolores Fernández-Ortuño"}]}],mostDownloadedChaptersLast30Days:[{id:"71993",title:"Edible Mushroom: Nutritional Properties, Potential Nutraceutical Values, and Its Utilisation in Food Product Development",slug:"edible-mushroom-nutritional-properties-potential-nutraceutical-values-and-its-utilisation-in-food-pr",totalDownloads:1471,totalCrossrefCites:8,totalDimensionsCites:15,abstract:"Edible mushrooms are an excellent source of proteins, minerals, polysaccharides, unsaturated fatty acids, and secondary metabolites. Numerous studies have provided evidence for the protective effects of edible mushrooms against various chronic diseases. In this review, details on the compositions and nutritional values of edible mushrooms were discussed. Furthermore, bioactive compounds such as polyphenolic compounds and antioxidant capacity of edible mushrooms, as well as the application of these edible mushrooms as potential therapeutic agents, were covered. This chapter also endeavoured to review the recent progress on the potential utilisation of edible mushrooms in the development of functional food products and its effects on the nutritional, physical, and organoleptic properties of the developed food products. Based on the recent socioeconomic trends, the substitution of edible mushroom as an essential source of functional ingredients in food products could become a natural adjuvant for the prevention and alleviation of several lifestyle-related diseases. This information could be beneficial for the development of food products with health functionalities, which are of great interest to the medical nutrition industry, which is an industry that emerged from the convergence between the food and pharma industries.",book:{id:"9463",slug:"an-introduction-to-mushroom",title:"An Introduction to Mushroom",fullTitle:"An Introduction to Mushroom"},signatures:"Lee-Hoon Ho, Noroul Asyikeen Zulkifli and Thuan-Chew Tan",authors:[{id:"305265",title:"Dr.",name:"Lee Hoon",middleName:null,surname:"Ho",slug:"lee-hoon-ho",fullName:"Lee Hoon Ho"},{id:"314538",title:"Dr.",name:"Noroul Asyikeen",middleName:null,surname:"Zulkifli",slug:"noroul-asyikeen-zulkifli",fullName:"Noroul Asyikeen Zulkifli"},{id:"314539",title:"Dr.",name:"Thuan-Chew",middleName:null,surname:"Tan",slug:"thuan-chew-tan",fullName:"Thuan-Chew Tan"}]},{id:"65413",title:"Introductory Chapter: Identification and Isolation of Trichoderma spp. - Their Significance in Agriculture, Human Health, Industrial and Environmental Application",slug:"introductory-chapter-identification-and-isolation-of-em-trichoderma-em-spp-their-significance-in-agr",totalDownloads:2950,totalCrossrefCites:2,totalDimensionsCites:4,abstract:null,book:{id:"8081",slug:"trichoderma-the-most-widely-used-fungicide",title:"Trichoderma",fullTitle:"Trichoderma - The Most Widely Used Fungicide"},signatures:"Mohammad Manjur Shah and Hamisu Afiya",authors:[{id:"94128",title:"Dr.",name:"Mohammad Manjur",middleName:null,surname:"Shah",slug:"mohammad-manjur-shah",fullName:"Mohammad Manjur Shah"}]},{id:"63094",title:"Emerging Pathogens of the Candida Species",slug:"emerging-pathogens-of-the-candida-species",totalDownloads:1858,totalCrossrefCites:4,totalDimensionsCites:4,abstract:"In recent years, opportunistic and nosocomial fungal pathogens have been dominated by yeasts of the genus Candida. Most of the research has focused on Candida albicans since it is the most prominent etiological agent. There are numerous publications that describe the biology, virulence factors, morphology, immunity, genomics, diseases, and laboratory aspects of Candida albicans. In this chapter we offer a historic perspective of C. albicans and focus on other non-albicans candida (NAC) that cause serious disease. We review the current knowledge of emerging NAC pathogens with useful graphics and current references. This chapter is laid out as an overview and is geared for students seeking basic information and may be superficial for an infectious diseases clinician.",book:{id:"6923",slug:"candida-albicans",title:"Candida Albicans",fullTitle:"Candida Albicans"},signatures:"Bo Yang and Reeta Rao",authors:[{id:"261208",title:"Associate Prof.",name:"Reeta",middleName:null,surname:"Rao",slug:"reeta-rao",fullName:"Reeta Rao"},{id:"268249",title:"Ms.",name:"Bo",middleName:null,surname:"Yang",slug:"bo-yang",fullName:"Bo Yang"}]},{id:"12734",title:"Introduction and Toxicology of Fungicides",slug:"introduction-and-toxicology-of-fungicides",totalDownloads:19626,totalCrossrefCites:7,totalDimensionsCites:16,abstract:null,book:{id:"22",slug:"fungicides",title:"Fungicides",fullTitle:"Fungicides"},signatures:"Rachid Rouabhi",authors:[{id:"13583",title:"Dr.",name:"Rachid",middleName:null,surname:"Rouabhi",slug:"rachid-rouabhi",fullName:"Rachid Rouabhi"}]},{id:"65709",title:"A Review Report on the Mechanism of Trichoderma spp. as Biological Control Agent of the Basal Stem Rot (BSR) Disease of Elaeis guineensis",slug:"a-review-report-on-the-mechanism-of-em-trichoderma-em-spp-as-biological-control-agent-of-the-basal-s",totalDownloads:1733,totalCrossrefCites:3,totalDimensionsCites:9,abstract:"Trichoderma spp. have been the most common fungi applied as biological control agents (BCA) as an effort to combat a wide range of plant diseases. Its uses have recorded good success rate in controlling major plant diseases. Knowledge on the mechanisms employed by Trichoderma spp. could be further studied to improve its ability as an efficient biocontrol agent. The Trichoderma ability to curb plant diseases were mainly based on the activation of single or multiple control mechanisms. It is known that the Trichoderma-based biocontrol mechanisms mainly rely on mycoparasitism, production of antibiotic and/or hydrolytic enzymes, competition for nutrients, as well as induced plant resistance; numerous secondary metabolites produced by Trichoderma species could directly inhibit the growth of several plant pathogens. These mechanisms may act directly or indirectly against the targeted plant pathogen. This chapter reviews the recent updates on published research findings on mechanisms used by Trichoderma as biological control of plant diseases particularly on basal stem rot disease of oil palm caused by Ganoderma spp.",book:{id:"8081",slug:"trichoderma-the-most-widely-used-fungicide",title:"Trichoderma",fullTitle:"Trichoderma - The Most Widely Used Fungicide"},signatures:"Syed Ali Nusaibah and Habu Musa",authors:null}],onlineFirstChaptersFilter:{topicId:"366",limit:6,offset:0},onlineFirstChaptersCollection:[],onlineFirstChaptersTotal:0},preDownload:{success:null,errors:{}},subscriptionForm:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[],offset:8,limit:8,total:0},allSeries:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:9,numberOfPublishedChapters:89,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:104,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:32,numberOfPublishedChapters:318,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:12,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:11,numberOfPublishedChapters:141,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:8,numberOfPublishedChapters:129,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!0},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:113,numberOfOpenTopics:3,numberOfUpcomingTopics:1,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:11,numberOfPublishedChapters:106,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2753-894X",doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:5,numberOfOpenTopics:1,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!0},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:0,numberOfPublishedChapters:15,numberOfOpenTopics:5,numberOfUpcomingTopics:0,issn:null,doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],testimonialsList:[{id:"6",text:"It is great to work with the IntechOpen to produce a worthwhile collection of research that also becomes a great educational resource and guide for future research endeavors.",author:{id:"259298",name:"Edward",surname:"Narayan",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259298/images/system/259298.jpeg",slug:"edward-narayan",institution:{id:"3",name:"University of Queensland",country:{id:null,name:"Australia"}}}},{id:"13",text:"The collaboration with and support of the technical staff of IntechOpen is fantastic. The whole process of submitting an article and editing of the submitted article goes extremely smooth and fast, the number of reads and downloads of chapters is high, and the contributions are also frequently cited.",author:{id:"55578",name:"Antonio",surname:"Jurado-Navas",institutionString:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRisIQAS/Profile_Picture_1626166543950",slug:"antonio-jurado-navas",institution:{id:"720",name:"University of Malaga",country:{id:null,name:"Spain"}}}}]},series:{item:{id:"11",title:"Biochemistry",doi:"10.5772/intechopen.72877",issn:"2632-0983",scope:"Biochemistry, the study of chemical transformations occurring within living organisms, impacts all areas of life sciences, from molecular crystallography and genetics to ecology, medicine, and population biology. Biochemistry examines macromolecules - proteins, nucleic acids, carbohydrates, and lipids – and their building blocks, structures, functions, and interactions. Much of biochemistry is devoted to enzymes, proteins that catalyze chemical reactions, enzyme structures, mechanisms of action and their roles within cells. Biochemistry also studies small signaling molecules, coenzymes, inhibitors, vitamins, and hormones, which play roles in life processes. Biochemical experimentation, besides coopting classical chemistry methods, e.g., chromatography, adopted new techniques, e.g., X-ray diffraction, electron microscopy, NMR, radioisotopes, and developed sophisticated microbial genetic tools, e.g., auxotroph mutants and their revertants, fermentation, etc. More recently, biochemistry embraced the ‘big data’ omics systems. Initial biochemical studies have been exclusively analytic: dissecting, purifying, and examining individual components of a biological system; in the apt words of Efraim Racker (1913 –1991), “Don’t waste clean thinking on dirty enzymes.” Today, however, biochemistry is becoming more agglomerative and comprehensive, setting out to integrate and describe entirely particular biological systems. The ‘big data’ metabolomics can define the complement of small molecules, e.g., in a soil or biofilm sample; proteomics can distinguish all the comprising proteins, e.g., serum; metagenomics can identify all the genes in a complex environment, e.g., the bovine rumen. This Biochemistry Series will address the current research on biomolecules and the emerging trends with great promise.",coverUrl:"https://cdn.intechopen.com/series/covers/11.jpg",latestPublicationDate:"June 29th, 2022",hasOnlineFirst:!0,numberOfPublishedBooks:32,editor:{id:"31610",title:"Dr.",name:"Miroslav",middleName:null,surname:"Blumenberg",slug:"miroslav-blumenberg",fullName:"Miroslav Blumenberg",profilePictureURL:"https://mts.intechopen.com/storage/users/31610/images/system/31610.jpg",biography:"Miroslav Blumenberg, Ph.D., was born in Subotica and received his BSc in Belgrade, Yugoslavia. He completed his Ph.D. at MIT in Organic Chemistry; he followed up his Ph.D. with two postdoctoral study periods at Stanford University. Since 1983, he has been a faculty member of the RO Perelman Department of Dermatology, NYU School of Medicine, where he is codirector of a training grant in cutaneous biology. Dr. Blumenberg’s research is focused on the epidermis, expression of keratin genes, transcription profiling, keratinocyte differentiation, inflammatory diseases and cancers, and most recently the effects of the microbiome on the skin. He has published more than 100 peer-reviewed research articles and graduated numerous Ph.D. and postdoctoral students.",institutionString:null,institution:{name:"New York University Langone Medical Center",institutionURL:null,country:{name:"United States of America"}}},editorTwo:null,editorThree:null},subseries:{paginationCount:2,paginationItems:[{id:"89",title:"Education",coverUrl:"https://cdn.intechopen.com/series_topics/covers/89.jpg",isOpenForSubmission:!1,editor:{id:"260066",title:"Associate Prof.",name:"Michail",middleName:null,surname:"Kalogiannakis",slug:"michail-kalogiannakis",fullName:"Michail Kalogiannakis",profilePictureURL:"https://mts.intechopen.com/storage/users/260066/images/system/260066.jpg",biography:"Michail Kalogiannakis is an Associate Professor of the Department of Preschool Education, University of Crete, and an Associate Tutor at School of Humanities at the Hellenic Open University. He graduated from the Physics Department of the University of Crete and continued his post-graduate studies at the University Paris 7-Denis Diderot (D.E.A. in Didactic of Physics), University Paris 5-René Descartes-Sorbonne (D.E.A. in Science Education) and received his Ph.D. degree at the University Paris 5-René Descartes-Sorbonne (PhD in Science Education). His research interests include science education in early childhood, science teaching and learning, e-learning, the use of ICT in science education, games simulations, and mobile learning. He has published over 120 articles in international conferences and journals and has served on the program committees of numerous international conferences.",institutionString:"University of Crete",institution:{name:"University of Crete",institutionURL:null,country:{name:"Greece"}}},editorTwo:{id:"422488",title:"Dr.",name:"Maria",middleName:null,surname:"Ampartzaki",slug:"maria-ampartzaki",fullName:"Maria Ampartzaki",profilePictureURL:"https://mts.intechopen.com/storage/users/422488/images/system/422488.jpg",biography:"Dr Maria Ampartzaki is an Assistant Professor in Early Childhood Education in the Department of Preschool Education at the University of Crete. Her research interests include ICT in education, science education in the early years, inquiry-based and art-based learning, teachers’ professional development, action research, and the Pedagogy of Multiliteracies, among others. She has run and participated in several funded and non-funded projects on the teaching of Science, Social Sciences, and ICT in education. She also has the experience of participating in five Erasmus+ projects.",institutionString:"University of Crete",institution:{name:"University of Crete",institutionURL:null,country:{name:"Greece"}}},editorThree:null},{id:"90",title:"Human Development",coverUrl:"https://cdn.intechopen.com/series_topics/covers/90.jpg",isOpenForSubmission:!0,editor:{id:"191040",title:"Dr.",name:"Tal",middleName:null,surname:"Dotan Ben-Soussan",slug:"tal-dotan-ben-soussan",fullName:"Tal Dotan Ben-Soussan",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSBf1QAG/Profile_Picture_2022-03-18T07:56:11.jpg",biography:"Tal Dotan Ben-Soussan, Ph.D., is the director of the Research Institute for Neuroscience, Education and Didactics (RINED) – Paoletti Foundation. Ben-Soussan leads international studies on training and neuroplasticity from neurophysiological and psychobiological perspectives. As a neuroscientist and bio-psychologist, she has published numerous articles on neuroplasticity, movement and meditation. She acts as an editor and reviewer in several renowned journals and coordinates international conferences integrating theoretical, methodological and practical approaches on various topics, such as silence, logics and neuro-education. She lives in Assisi, Italy.",institutionString:"Research Institute for Neuroscience, Education and Didactics, Patrizio Paoletti Foundation",institution:null},editorTwo:null,editorThree:null}]},overviewPageOFChapters:{paginationCount:5,paginationItems:[{id:"82394",title:"Learning by Doing Active Social Learning",doi:"10.5772/intechopen.105523",signatures:"Anat Raviv",slug:"learning-by-doing-active-social-learning",totalDownloads:3,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Active Learning - Research and Practice",coverURL:"https://cdn.intechopen.com/books/images_new/11481.jpg",subseries:{id:"89",title:"Education"}}},{id:"82310",title:"Knowledge of Intergenerational Contact to Combat Ageism towards Older People",doi:"10.5772/intechopen.105592",signatures:"Alice Nga Lai Kwong",slug:"knowledge-of-intergenerational-contact-to-combat-ageism-towards-older-people",totalDownloads:8,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Social Aspects of Ageing - Selected Challenges, Analyses, and Solutions",coverURL:"https://cdn.intechopen.com/books/images_new/11479.jpg",subseries:{id:"90",title:"Human Development"}}},{id:"81993",title:"Emergent Chemistry: Using Visualizations to Develop Abstract Thinking and a Sense of Scale Within the Preschool Setting",doi:"10.5772/intechopen.105216",signatures:"Karina Adbo",slug:"emergent-chemistry-using-visualizations-to-develop-abstract-thinking-and-a-sense-of-scale-within-the",totalDownloads:5,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Active Learning - Research and Practice",coverURL:"https://cdn.intechopen.com/books/images_new/11481.jpg",subseries:{id:"89",title:"Education"}}},{id:"82252",title:"Early Childhood: Enriched Environments and Roles of Caring Adults",doi:"10.5772/intechopen.105157",signatures:"Analía Mignaton",slug:"early-childhood-enriched-environments-and-roles-of-caring-adults",totalDownloads:4,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Active Learning - Research and Practice",coverURL:"https://cdn.intechopen.com/books/images_new/11481.jpg",subseries:{id:"89",title:"Education"}}}]},overviewPagePublishedBooks:{paginationCount:0,paginationItems:[]},openForSubmissionBooks:{paginationCount:3,paginationItems:[{id:"11578",title:"Antibiotics and Probiotics in Animal Food - Impact and Regulation",coverURL:"https://cdn.intechopen.com/books/images_new/11578.jpg",hash:"3731c009f474c6ed4293f348ca7b27ac",secondStepPassed:!0,currentStepOfPublishingProcess:3,submissionDeadline:"June 3rd 2022",isOpenForSubmission:!0,editors:[{id:"225390",title:"Dr.",name:"Asghar Ali",surname:"Kamboh",slug:"asghar-ali-kamboh",fullName:"Asghar Ali Kamboh"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{id:"12086",title:"Cattle Diseases - Molecular and Biochemical Approach",coverURL:"https://cdn.intechopen.com/books/images_new/12086.jpg",hash:"afdbf57e32d996556a94528c06623cf3",secondStepPassed:!1,currentStepOfPublishingProcess:2,submissionDeadline:"July 5th 2022",isOpenForSubmission:!0,editors:[{id:"219081",title:"Dr.",name:"Abdulsamed",surname:"Kükürt",slug:"abdulsamed-kukurt",fullName:"Abdulsamed Kükürt"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{id:"11579",title:"Animal Welfare - New Insights",coverURL:"https://cdn.intechopen.com/books/images_new/11579.jpg",hash:"12e4f41264cbe99028655e5463fa941a",secondStepPassed:!1,currentStepOfPublishingProcess:2,submissionDeadline:"July 8th 2022",isOpenForSubmission:!0,editors:[{id:"51520",title:"Dr.",name:"Shao-Wen",surname:"Hung",slug:"shao-wen-hung",fullName:"Shao-Wen Hung"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null}]},onlineFirstChapters:{paginationCount:36,paginationItems:[{id:"82195",title:"Endoplasmic Reticulum: A Hub in Lipid Homeostasis",doi:"10.5772/intechopen.105450",signatures:"Raúl Ventura and María Isabel Hernández-Alvarez",slug:"endoplasmic-reticulum-a-hub-in-lipid-homeostasis",totalDownloads:4,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Updates on Endoplasmic Reticulum",coverURL:"https://cdn.intechopen.com/books/images_new/11674.jpg",subseries:{id:"14",title:"Cell and Molecular Biology"}}},{id:"82409",title:"Purinergic Signaling in Covid-19 Disease",doi:"10.5772/intechopen.105008",signatures:"Hailian Shen",slug:"purinergic-signaling-in-covid-19-disease",totalDownloads:5,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Purinergic System",coverURL:"https://cdn.intechopen.com/books/images_new/10801.jpg",subseries:{id:"17",title:"Metabolism"}}},{id:"82374",title:"The Potential of the Purinergic System as a Therapeutic Target of Natural Compounds in Cutaneous Melanoma",doi:"10.5772/intechopen.105457",signatures:"Gilnei Bruno da Silva, Daiane Manica, Marcelo Moreno and Margarete Dulce Bagatini",slug:"the-potential-of-the-purinergic-system-as-a-therapeutic-target-of-natural-compounds-in-cutaneous-mel",totalDownloads:10,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Purinergic System",coverURL:"https://cdn.intechopen.com/books/images_new/10801.jpg",subseries:{id:"17",title:"Metabolism"}}},{id:"82103",title:"The Role of Endoplasmic Reticulum Stress and Its Regulation in the Progression of Neurological and Infectious Diseases",doi:"10.5772/intechopen.105543",signatures:"Mary Dover, Michael Kishek, Miranda Eddins, Naneeta Desar, Ketema Paul and Milan Fiala",slug:"the-role-of-endoplasmic-reticulum-stress-and-its-regulation-in-the-progression-of-neurological-and-i",totalDownloads:6,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Updates on Endoplasmic Reticulum",coverURL:"https://cdn.intechopen.com/books/images_new/11674.jpg",subseries:{id:"14",title:"Cell and Molecular Biology"}}},{id:"82212",title:"Protein Prenylation and Their Applications",doi:"10.5772/intechopen.104700",signatures:"Khemchand R. Surana, Ritesh B. Pawar, Ritesh A. Khairnar and Sunil K. Mahajan",slug:"protein-prenylation-and-their-applications",totalDownloads:9,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Modifications of Biomolecules",coverURL:"https://cdn.intechopen.com/books/images_new/11098.jpg",subseries:null}},{id:"80954",title:"Ion Channels and Neurodegenerative Disease Aging Related",doi:"10.5772/intechopen.103074",signatures:"Marika Cordaro, Salvatore Cuzzocrea and Rosanna Di Paola",slug:"ion-channels-and-neurodegenerative-disease-aging-related",totalDownloads:7,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Ion Channels - From Basic Properties to Medical Treatment",coverURL:"https://cdn.intechopen.com/books/images_new/10838.jpg",subseries:{id:"14",title:"Cell and Molecular Biology"}}},{id:"82096",title:"An Important Component of Tumor Progression: Fatty Acids",doi:"10.5772/intechopen.105087",signatures:"Jin Wang, Qifei Wang and Guangzhen Wu",slug:"an-important-component-of-tumor-progression-fatty-acids",totalDownloads:9,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Fatty Acids - Recent Advances",coverURL:"https://cdn.intechopen.com/books/images_new/11669.jpg",subseries:{id:"17",title:"Metabolism"}}},{id:"82029",title:"Synthesis, Characterization and Antimicrobial Properties of Novel Benzimidazole Amide Derivatives Bearing Thiophene Moiety",doi:"10.5772/intechopen.104908",signatures:"Vinayak Adimule, Pravin Kendrekar and Sheetal Batakurki",slug:"synthesis-characterization-and-antimicrobial-properties-of-novel-benzimidazole-amide-derivatives-bea",totalDownloads:4,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Benzimidazole",coverURL:"https://cdn.intechopen.com/books/images_new/10840.jpg",subseries:{id:"15",title:"Chemical Biology"}}},{id:"81927",title:"Purinergic System in Immune Response",doi:"10.5772/intechopen.104485",signatures:"Yerly Magnolia Useche Salvador",slug:"purinergic-system-in-immune-response",totalDownloads:15,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Purinergic System",coverURL:"https://cdn.intechopen.com/books/images_new/10801.jpg",subseries:{id:"17",title:"Metabolism"}}},{id:"80495",title:"Iron in Cell Metabolism and Disease",doi:"10.5772/intechopen.101908",signatures:"Eeka Prabhakar",slug:"iron-in-cell-metabolism-and-disease",totalDownloads:16,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Iron Metabolism - Iron a Double‐Edged Sword",coverURL:"https://cdn.intechopen.com/books/images_new/10842.jpg",subseries:{id:"17",title:"Metabolism"}}}]},subseriesFiltersForOFChapters:[{caption:"Proteomics",value:18,count:1,group:"subseries"},{caption:"Chemical Biology",value:15,count:5,group:"subseries"},{caption:"Metabolism",value:17,count:13,group:"subseries"},{caption:"Cell and Molecular Biology",value:14,count:15,group:"subseries"}],publishedBooks:{paginationCount:32,paginationItems:[{type:"book",id:"10798",title:"Starch",subtitle:"Evolution and Recent Advances",coverURL:"https://cdn.intechopen.com/books/images_new/10798.jpg",slug:"starch-evolution-and-recent-advances",publishedDate:"June 28th 2022",editedByType:"Edited by",bookSignature:"Martins Ochubiojo Emeje",hash:"f197f6062c1574a9a90e50a369271bcf",volumeInSeries:33,fullTitle:"Starch - Evolution and Recent Advances",editors:[{id:"94311",title:"Prof.",name:"Martins",middleName:"Ochubiojo",surname:"Ochubiojo Emeje",slug:"martins-ochubiojo-emeje",fullName:"Martins Ochubiojo Emeje",profilePictureURL:"https://mts.intechopen.com/storage/users/94311/images/system/94311.jpeg",institutionString:"National Institute for Pharmaceutical Research and Development",institution:{name:"National Institute for Pharmaceutical Research and Development",institutionURL:null,country:{name:"Nigeria"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"11332",title:"Essential Oils",subtitle:"Advances in Extractions and Biological Applications",coverURL:"https://cdn.intechopen.com/books/images_new/11332.jpg",slug:"essential-oils-advances-in-extractions-and-biological-applications",publishedDate:"June 23rd 2022",editedByType:"Edited by",bookSignature:"Mozaniel Santana de Oliveira and Eloisa Helena de Aguiar Andrade",hash:"742e6cae3a35686f975edc8d7f9afa94",volumeInSeries:32,fullTitle:"Essential Oils - Advances in Extractions and Biological Applications",editors:[{id:"195290",title:"Ph.D.",name:"Mozaniel",middleName:null,surname:"Santana De Oliveira",slug:"mozaniel-santana-de-oliveira",fullName:"Mozaniel Santana De Oliveira",profilePictureURL:"https://mts.intechopen.com/storage/users/195290/images/system/195290.png",institutionString:"Museu Paraense Emílio Goeldi",institution:{name:"Museu Paraense Emílio Goeldi",institutionURL:null,country:{name:"Brazil"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"10839",title:"Protein Detection",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/10839.jpg",slug:"protein-detection",publishedDate:"June 23rd 2022",editedByType:"Edited by",bookSignature:"Yusuf Tutar and Lütfi Tutar",hash:"2f1c0e4e0207fc45c936e7d22a5369c4",volumeInSeries:31,fullTitle:"Protein Detection",editors:[{id:"158492",title:"Prof.",name:"Yusuf",middleName:null,surname:"Tutar",slug:"yusuf-tutar",fullName:"Yusuf Tutar",profilePictureURL:"https://mts.intechopen.com/storage/users/158492/images/system/158492.jpeg",institutionString:"University of Health Sciences",institution:null}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"10797",title:"Cell Culture",subtitle:"Advanced Technology and Applications in Medical and Life Sciences",coverURL:"https://cdn.intechopen.com/books/images_new/10797.jpg",slug:"cell-culture-advanced-technology-and-applications-in-medical-and-life-sciences",publishedDate:"June 15th 2022",editedByType:"Edited by",bookSignature:"Xianquan Zhan",hash:"2c628f4757f9639a4450728d839a7842",volumeInSeries:30,fullTitle:"Cell Culture - Advanced Technology and Applications in Medical and Life Sciences",editors:[{id:"223233",title:"Prof.",name:"Xianquan",middleName:null,surname:"Zhan",slug:"xianquan-zhan",fullName:"Xianquan Zhan",profilePictureURL:"https://mts.intechopen.com/storage/users/223233/images/system/223233.png",institutionString:"Shandong First Medical University",institution:{name:"Affiliated Hospital of Shandong Academy of Medical Sciences",institutionURL:null,country:{name:"China"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"10841",title:"Hydrolases",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/10841.jpg",slug:"hydrolases",publishedDate:"June 15th 2022",editedByType:"Edited by",bookSignature:"Sajjad Haider, Adnan Haider and Angel Catalá",hash:"4e868cde273d65a7ff54b1817d640629",volumeInSeries:29,fullTitle:"Hydrolases",editors:[{id:"110708",title:"Dr.",name:"Sajjad",middleName:null,surname:"Haider",slug:"sajjad-haider",fullName:"Sajjad Haider",profilePictureURL:"https://mts.intechopen.com/storage/users/110708/images/system/110708.png",institutionString:"King Saud University",institution:{name:"King Saud University",institutionURL:null,country:{name:"Saudi Arabia"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"10803",title:"Reactive Oxygen Species",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/10803.jpg",slug:"reactive-oxygen-species",publishedDate:"April 28th 2022",editedByType:"Edited by",bookSignature:"Rizwan Ahmad",hash:"176adcf090fdd1f93cb8ce3146e79ca1",volumeInSeries:28,fullTitle:"Reactive Oxygen Species",editors:[{id:"40482",title:null,name:"Rizwan",middleName:null,surname:"Ahmad",slug:"rizwan-ahmad",fullName:"Rizwan Ahmad",profilePictureURL:"https://mts.intechopen.com/storage/users/40482/images/system/40482.jpeg",institutionString:"Imam Abdulrahman Bin Faisal University",institution:{name:"Imam Abdulrahman Bin Faisal University",institutionURL:null,country:{name:"Saudi Arabia"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"9008",title:"Vitamin K",subtitle:"Recent Topics on the Biology and Chemistry",coverURL:"https://cdn.intechopen.com/books/images_new/9008.jpg",slug:"vitamin-k-recent-topics-on-the-biology-and-chemistry",publishedDate:"March 23rd 2022",editedByType:"Edited by",bookSignature:"Hiroyuki Kagechika and Hitoshi Shirakawa",hash:"8b43add5389ba85743e0a9491e4b9943",volumeInSeries:27,fullTitle:"Vitamin K - Recent Topics on the Biology and Chemistry",editors:[{id:"180528",title:"Dr.",name:"Hiroyuki",middleName:null,surname:"Kagechika",slug:"hiroyuki-kagechika",fullName:"Hiroyuki Kagechika",profilePictureURL:"https://mts.intechopen.com/storage/users/180528/images/system/180528.jpg",institutionString:"Tokyo Medical and Dental University",institution:{name:"Tokyo Medical and Dental University",institutionURL:null,country:{name:"Japan"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"10799",title:"Phenolic Compounds",subtitle:"Chemistry, Synthesis, Diversity, Non-Conventional Industrial, Pharmaceutical and Therapeutic Applications",coverURL:"https://cdn.intechopen.com/books/images_new/10799.jpg",slug:"phenolic-compounds-chemistry-synthesis-diversity-non-conventional-industrial-pharmaceutical-and-therapeutic-applications",publishedDate:"February 23rd 2022",editedByType:"Edited by",bookSignature:"Farid A. Badria",hash:"339199f254d2987ef3167eef74fb8a38",volumeInSeries:26,fullTitle:"Phenolic Compounds - Chemistry, Synthesis, Diversity, Non-Conventional Industrial, Pharmaceutical and Therapeutic Applications",editors:[{id:"41865",title:"Prof.",name:"Farid A.",middleName:null,surname:"Badria",slug:"farid-a.-badria",fullName:"Farid A. Badria",profilePictureURL:"https://mts.intechopen.com/storage/users/41865/images/system/41865.jpg",institutionString:"Mansoura University",institution:{name:"Mansoura University",institutionURL:null,country:{name:"Egypt"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"9659",title:"Fibroblasts",subtitle:"Advances in Inflammation, Autoimmunity and Cancer",coverURL:"https://cdn.intechopen.com/books/images_new/9659.jpg",slug:"fibroblasts-advances-in-inflammation-autoimmunity-and-cancer",publishedDate:"December 22nd 2021",editedByType:"Edited by",bookSignature:"Mojca Frank Bertoncelj and Katja Lakota",hash:"926fa6446f6befbd363fc74971a56de2",volumeInSeries:25,fullTitle:"Fibroblasts - Advances in Inflammation, Autoimmunity and Cancer",editors:[{id:"328755",title:"Ph.D.",name:"Mojca",middleName:null,surname:"Frank Bertoncelj",slug:"mojca-frank-bertoncelj",fullName:"Mojca Frank Bertoncelj",profilePictureURL:"https://mts.intechopen.com/storage/users/328755/images/system/328755.jpg",institutionString:"BioMed X Institute",institution:{name:"University Hospital of Zurich",institutionURL:null,country:{name:"Switzerland"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"8977",title:"Protein Kinases",subtitle:"Promising Targets for Anticancer Drug Research",coverURL:"https://cdn.intechopen.com/books/images_new/8977.jpg",slug:"protein-kinases-promising-targets-for-anticancer-drug-research",publishedDate:"December 8th 2021",editedByType:"Edited by",bookSignature:"Rajesh Kumar Singh",hash:"6d200cc031706a565b554fdb1c478901",volumeInSeries:24,fullTitle:"Protein Kinases - Promising Targets for Anticancer Drug Research",editors:[{id:"329385",title:"Dr.",name:"Rajesh K.",middleName:"Kumar",surname:"Singh",slug:"rajesh-k.-singh",fullName:"Rajesh K. Singh",profilePictureURL:"https://mts.intechopen.com/storage/users/329385/images/system/329385.png",institutionString:"Punjab Technical University",institution:{name:"Punjab Technical University",institutionURL:null,country:{name:"India"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"8018",title:"Extracellular Matrix",subtitle:"Developments and Therapeutics",coverURL:"https://cdn.intechopen.com/books/images_new/8018.jpg",slug:"extracellular-matrix-developments-and-therapeutics",publishedDate:"October 27th 2021",editedByType:"Edited by",bookSignature:"Rama Sashank Madhurapantula, Joseph Orgel P.R.O. and Zvi Loewy",hash:"c85e82851e80b40282ff9be99ddf2046",volumeInSeries:23,fullTitle:"Extracellular Matrix - Developments and Therapeutics",editors:[{id:"212416",title:"Dr.",name:"Rama Sashank",middleName:null,surname:"Madhurapantula",slug:"rama-sashank-madhurapantula",fullName:"Rama Sashank Madhurapantula",profilePictureURL:"https://mts.intechopen.com/storage/users/212416/images/system/212416.jpg",institutionString:"Illinois Institute of Technology",institution:{name:"Illinois Institute of Technology",institutionURL:null,country:{name:"United States of America"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"9759",title:"Vitamin E in Health and Disease",subtitle:"Interactions, Diseases and Health Aspects",coverURL:"https://cdn.intechopen.com/books/images_new/9759.jpg",slug:"vitamin-e-in-health-and-disease-interactions-diseases-and-health-aspects",publishedDate:"October 6th 2021",editedByType:"Edited by",bookSignature:"Pınar Erkekoglu and Júlia Scherer Santos",hash:"6c3ddcc13626110de289b57f2516ac8f",volumeInSeries:22,fullTitle:"Vitamin E in Health and Disease - Interactions, Diseases and Health Aspects",editors:[{id:"109978",title:"Prof.",name:"Pınar",middleName:null,surname:"Erkekoğlu",slug:"pinar-erkekoglu",fullName:"Pınar Erkekoğlu",profilePictureURL:"https://mts.intechopen.com/storage/users/109978/images/system/109978.jpg",institutionString:"Hacettepe University",institution:{name:"Hacettepe University",institutionURL:null,country:{name:"Turkey"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null}]},subseriesFiltersForPublishedBooks:[{group:"subseries",caption:"Proteomics",value:18,count:4},{group:"subseries",caption:"Metabolism",value:17,count:6},{group:"subseries",caption:"Cell and Molecular Biology",value:14,count:9},{group:"subseries",caption:"Chemical Biology",value:15,count:13}],publicationYearFilters:[{group:"publicationYear",caption:"2022",value:2022,count:8},{group:"publicationYear",caption:"2021",value:2021,count:7},{group:"publicationYear",caption:"2020",value:2020,count:12},{group:"publicationYear",caption:"2019",value:2019,count:3},{group:"publicationYear",caption:"2018",value:2018,count:2}],authors:{paginationCount:301,paginationItems:[{id:"116250",title:"Dr.",name:"Nima",middleName:null,surname:"Rezaei",slug:"nima-rezaei",fullName:"Nima Rezaei",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/116250/images/system/116250.jpg",biography:"Professor Nima Rezaei obtained an MD from Tehran University of Medical Sciences, Iran. He also obtained an MSc in Molecular and Genetic Medicine, and a Ph.D. in Clinical Immunology and Human Genetics from the University of Sheffield, UK. He also completed a short-term fellowship in Pediatric Clinical Immunology and Bone Marrow Transplantation at Newcastle General Hospital, England. Dr. Rezaei is a Full Professor of Immunology and Vice Dean of International Affairs and Research, at the School of Medicine, Tehran University of Medical Sciences, and the co-founder and head of the Research Center for Immunodeficiencies. He is also the founding president of the Universal Scientific Education and Research Network (USERN). Dr. Rezaei has directed more than 100 research projects and has designed and participated in several international collaborative projects. He is an editor, editorial assistant, or editorial board member of more than forty international journals. He has edited more than 50 international books, presented more than 500 lectures/posters in congresses/meetings, and published more than 1,100 scientific papers in international journals.",institutionString:"Tehran University of Medical Sciences",institution:{name:"Tehran University of Medical Sciences",country:{name:"Iran"}}},{id:"180733",title:"Dr.",name:"Jean",middleName:null,surname:"Engohang-Ndong",slug:"jean-engohang-ndong",fullName:"Jean Engohang-Ndong",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/180733/images/system/180733.png",biography:"Dr. Jean Engohang-Ndong was born and raised in Gabon. After obtaining his Associate Degree of Science at the University of Science and Technology of Masuku, Gabon, he continued his education in France where he obtained his BS, MS, and Ph.D. in Medical Microbiology. He worked as a post-doctoral fellow at the Public Health Research Institute (PHRI), Newark, NJ for four years before accepting a three-year faculty position at Brigham Young University-Hawaii. Dr. Engohang-Ndong is a tenured faculty member with the academic rank of Full Professor at Kent State University, Ohio, where he teaches a wide range of biological science courses and pursues his research in medical and environmental microbiology. Recently, he expanded his research interest to epidemiology and biostatistics of chronic diseases in Gabon.",institutionString:"Kent State University",institution:{name:"Kent State University",country:{name:"United States of America"}}},{id:"188773",title:"Prof.",name:"Emmanuel",middleName:null,surname:"Drouet",slug:"emmanuel-drouet",fullName:"Emmanuel Drouet",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/188773/images/system/188773.png",biography:"Emmanuel Drouet, PharmD, is a Professor of Virology at the Faculty of Pharmacy, the University Grenoble-Alpes, France. As a head scientist at the Institute of Structural Biology in Grenoble, Dr. Drouet’s research investigates persisting viruses in humans (RNA and DNA viruses) and the balance with our host immune system. He focuses on these viruses’ effects on humans (both their impact on pathology and their symbiotic relationships in humans). He has an excellent track record in the herpesvirus field, and his group is engaged in clinical research in the field of Epstein-Barr virus diseases. He is the editor of the online Encyclopedia of Environment and he coordinates the Universal Health Coverage education program for the BioHealth Computing Schools of the European Institute of Science.",institutionString:null,institution:{name:"Grenoble Alpes University",country:{name:"France"}}},{id:"131400",title:"Prof.",name:"Alfonso J.",middleName:null,surname:"Rodriguez-Morales",slug:"alfonso-j.-rodriguez-morales",fullName:"Alfonso J. Rodriguez-Morales",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/131400/images/system/131400.png",biography:"Dr. Rodriguez-Morales is an expert in tropical and emerging diseases, particularly zoonotic and vector-borne diseases (especially arboviral diseases). He is the president of the Travel Medicine Committee of the Pan-American Infectious Diseases Association (API), as well as the president of the Colombian Association of Infectious Diseases (ACIN). He is a member of the Committee on Tropical Medicine, Zoonoses, and Travel Medicine of ACIN. He is a vice-president of the Latin American Society for Travel Medicine (SLAMVI) and a Member of the Council of the International Society for Infectious Diseases (ISID). Since 2014, he has been recognized as a Senior Researcher, at the Ministry of Science of Colombia. He is a professor at the Faculty of Medicine of the Fundacion Universitaria Autonoma de las Americas, in Pereira, Risaralda, Colombia. He is an External Professor, Master in Research on Tropical Medicine and International Health, Universitat de Barcelona, Spain. He is also a professor at the Master in Clinical Epidemiology and Biostatistics, Universidad Científica del Sur, Lima, Peru. In 2021 he has been awarded the “Raul Isturiz Award” Medal of the API. Also, in 2021, he was awarded with the “Jose Felix Patiño” Asclepius Staff Medal of the Colombian Medical College, due to his scientific contributions to COVID-19 during the pandemic. He is currently the Editor in Chief of the journal Travel Medicine and Infectious Diseases. His Scopus H index is 47 (Google Scholar H index, 68).",institutionString:"Institución Universitaria Visión de las Américas, Colombia",institution:null},{id:"332819",title:"Dr.",name:"Chukwudi Michael",middleName:"Michael",surname:"Egbuche",slug:"chukwudi-michael-egbuche",fullName:"Chukwudi Michael Egbuche",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/332819/images/14624_n.jpg",biography:"I an Dr. Chukwudi Michael Egbuche. I am a Senior Lecturer in the Department of Parasitology and Entomology, Nnamdi Azikiwe University, Awka.",institutionString:null,institution:{name:"Nnamdi Azikiwe University",country:{name:"Nigeria"}}},{id:"284232",title:"Mr.",name:"Nikunj",middleName:"U",surname:"Tandel",slug:"nikunj-tandel",fullName:"Nikunj Tandel",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/284232/images/8275_n.jpg",biography:'Mr. Nikunj Tandel has completed his Master\'s degree in Biotechnology from VIT University, India in the year of 2012. He is having 8 years of research experience especially in the field of malaria epidemiology, immunology, and nanoparticle-based drug delivery system against the infectious diseases, autoimmune disorders and cancer. He has worked for the NIH funded-International Center of Excellence in Malaria Research project "Center for the study of complex malaria in India (CSCMi)" in collaboration with New York University. The preliminary objectives of the study are to understand and develop the evidence-based tools and interventions for the control and prevention of malaria in different sites of the INDIA. Alongside, with the help of next-generation genomics study, the team has studied the antimalarial drug resistance in India. Further, he has extended his research in the development of Humanized mice for the study of liver-stage malaria and identification of molecular marker(s) for the Artemisinin resistance. At present, his research focuses on understanding the role of B cells in the activation of CD8+ T cells in malaria. Received the CSIR-SRF (Senior Research Fellow) award-2018, FIMSA (Federation of Immunological Societies of Asia-Oceania) Travel Bursary award to attend the IUIS-IIS-FIMSA Immunology course-2019',institutionString:"Nirma University",institution:{name:"Nirma University",country:{name:"India"}}},{id:"334383",title:"Ph.D.",name:"Simone",middleName:"Ulrich",surname:"Ulrich Picoli",slug:"simone-ulrich-picoli",fullName:"Simone Ulrich Picoli",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/334383/images/15919_n.jpg",biography:"Graduated in Pharmacy from Universidade Luterana do Brasil (1999), Master in Agricultural and Environmental Microbiology from Federal University of Rio Grande do Sul (2002), Specialization in Clinical Microbiology from Universidade de São Paulo, USP (2007) and PhD in Sciences in Gastroenterology and Hepatology (2012). She is currently an Adjunct Professor at Feevale University in Medicine and Biomedicine courses and a permanent professor of the Academic Master\\'s Degree in Virology. She has experience in the field of Microbiology, with an emphasis on Bacteriology, working mainly on the following topics: bacteriophages, bacterial resistance, clinical microbiology and food microbiology.",institutionString:null,institution:{name:"Universidade Feevale",country:{name:"Brazil"}}},{id:"229220",title:"Dr.",name:"Amjad",middleName:"Islam",surname:"Aqib",slug:"amjad-aqib",fullName:"Amjad Aqib",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/229220/images/system/229220.png",biography:"Dr. Amjad Islam Aqib obtained a DVM and MSc (Hons) from University of Agriculture Faisalabad (UAF), Pakistan, and a PhD from the University of Veterinary and Animal Sciences Lahore, Pakistan. Dr. Aqib joined the Department of Clinical Medicine and Surgery at UAF for one year as an assistant professor where he developed a research laboratory designated for pathogenic bacteria. Since 2018, he has been Assistant Professor/Officer in-charge, Department of Medicine, Manager Research Operations and Development-ORIC, and President One Health Club at Cholistan University of Veterinary and Animal Sciences, Bahawalpur, Pakistan. He has nearly 100 publications to his credit. His research interests include epidemiological patterns and molecular analysis of antimicrobial resistance and modulation and vaccine development against animal pathogens of public health concern.",institutionString:"Cholistan University of Veterinary and Animal Sciences",institution:null},{id:"62900",title:"Prof.",name:"Fethi",middleName:null,surname:"Derbel",slug:"fethi-derbel",fullName:"Fethi Derbel",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/62900/images/system/62900.jpeg",biography:"Professor Fethi Derbel was born in 1960 in Tunisia. He received his medical degree from the Sousse Faculty of Medicine at Sousse, University of Sousse, Tunisia. He completed his surgical residency in General Surgery at the University Hospital Farhat Hached of Sousse and was a member of the Unit of Liver Transplantation in the University of Rennes, France. He then worked in the Department of Surgery at the Sahloul University Hospital in Sousse. Professor Derbel is presently working at the Clinique les Oliviers, Sousse, Tunisia. His hospital activities are mostly concerned with laparoscopic, colorectal, pancreatic, hepatobiliary, and gastric surgery. He is also very interested in hernia surgery and performs ventral hernia repairs and inguinal hernia repairs. He has been a member of the GREPA and Tunisian Hernia Society (THS). During his residency, he managed patients suffering from diabetic foot, and he was very interested in this pathology. For this reason, he decided to coordinate a book project dealing with the diabetic foot. Professor Derbel has published many articles in journals and collaborates intensively with IntechOpen Access Publisher as an editor.",institutionString:"Clinique les Oliviers",institution:null},{id:"300144",title:"Dr.",name:"Meriem",middleName:null,surname:"Braiki",slug:"meriem-braiki",fullName:"Meriem Braiki",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/300144/images/system/300144.jpg",biography:"Dr. Meriem Braiki is a specialist in pediatric surgeon from Tunisia. She was born in 1985. She received her medical degree from the University of Medicine at Sousse, Tunisia. She achieved her surgical residency training periods in Pediatric Surgery departments at University Hospitals in Monastir, Tunis and France.\r\nShe is currently working at the Pediatric surgery department, Sidi Bouzid Hospital, Tunisia. Her hospital activities are mostly concerned with laparoscopic, parietal, urological and digestive surgery. She has published several articles in diffrent journals.",institutionString:"Sidi Bouzid Regional Hospital",institution:null},{id:"229481",title:"Dr.",name:"Erika M.",middleName:"Martins",surname:"de Carvalho",slug:"erika-m.-de-carvalho",fullName:"Erika M. de Carvalho",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/229481/images/6397_n.jpg",biography:null,institutionString:null,institution:{name:"Oswaldo Cruz Foundation",country:{name:"Brazil"}}},{id:"186537",title:"Prof.",name:"Tonay",middleName:null,surname:"Inceboz",slug:"tonay-inceboz",fullName:"Tonay Inceboz",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/186537/images/system/186537.jfif",biography:"I was graduated from Ege University of Medical Faculty (Turkey) in 1988 and completed his Med. PhD degree in Medical Parasitology at the same university. I became an Associate Professor in 2008 and Professor in 2014. I am currently working as a Professor at the Department of Medical Parasitology at Dokuz Eylul University, Izmir, Turkey.\n\nI have given many lectures, presentations in different academic meetings. I have more than 60 articles in peer-reviewed journals, 18 book chapters, 1 book editorship.\n\nMy research interests are Echinococcus granulosus, Echinococcus multilocularis (diagnosis, life cycle, in vitro and in vivo cultivation), and Trichomonas vaginalis (diagnosis, PCR, and in vitro cultivation).",institutionString:"Dokuz Eylül University",institution:{name:"Dokuz Eylül University",country:{name:"Turkey"}}},{id:"71812",title:"Prof.",name:"Hanem Fathy",middleName:"Fathy",surname:"Khater",slug:"hanem-fathy-khater",fullName:"Hanem Fathy Khater",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/71812/images/1167_n.jpg",biography:"Prof. Khater is a Professor of Parasitology at Benha University, Egypt. She studied for her doctoral degree, at the Department of Entomology, College of Agriculture, Food and Natural Resources, University of Missouri, Columbia, USA. She has completed her Ph.D. degrees in Parasitology in Egypt, from where she got the award for “the best scientific Ph.D. dissertation”. She worked at the School of Biological Sciences, Bristol, England, the UK in controlling insects of medical and veterinary importance as a grant from Newton Mosharafa, the British Council. Her research is focused on searching of pesticides against mosquitoes, house flies, lice, green bottle fly, camel nasal botfly, soft and hard ticks, mites, and the diamondback moth as well as control of several parasites using safe and natural materials to avoid drug resistances and environmental contamination.",institutionString:null,institution:{name:"Banha University",country:{name:"Egypt"}}},{id:"99780",title:"Prof.",name:"Omolade",middleName:"Olayinka",surname:"Okwa",slug:"omolade-okwa",fullName:"Omolade Okwa",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/99780/images/system/99780.jpg",biography:"Omolade Olayinka Okwa is presently a Professor of Parasitology at Lagos State University, Nigeria. She has a PhD in Parasitology (1997), an MSc in Cellular Parasitology (1992), and a BSc (Hons) Zoology (1990) all from the University of Ibadan, Nigeria. She teaches parasitology at the undergraduate and postgraduate levels. She was a recipient of a Commonwealth fellowship supported by British Council tenable at the Centre for Entomology and Parasitology (CAEP), Keele University, United Kingdom between 2004 and 2005. She was awarded an Honorary Visiting Research Fellow at the same university from 2005 to 2007. \nShe has been an external examiner to the Department of Veterinary Microbiology and Parasitology, University of Ibadan, MSc programme between 2010 and 2012. She is a member of the Nigerian Society of Experimental Biology (NISEB), Parasitology and Public Health Society of Nigeria (PPSN), Science Association of Nigeria (SAN), Zoological Society of Nigeria (ZSN), and is Vice Chairperson of the Organisation of Women in Science (OWSG), LASU chapter. She served as Head of Department of Zoology and Environmental Biology, Lagos State University from 2007 to 2010 and 2014 to 2016. She is a reviewer for several local and international journals such as Unilag Journal of Science, Libyan Journal of Medicine, Journal of Medicine and Medical Sciences, and Annual Research and Review in Science. \nShe has authored 45 scientific research publications in local and international journals, 8 scientific reviews, 4 books, and 3 book chapters, which includes the books “Malaria Parasites” and “Malaria” which are IntechOpen access publications.",institutionString:"Lagos State University",institution:{name:"Lagos State University",country:{name:"Nigeria"}}},{id:"273100",title:"Dr.",name:"Vijay",middleName:null,surname:"Gayam",slug:"vijay-gayam",fullName:"Vijay Gayam",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/273100/images/system/273100.jpeg",biography:"Dr. Vijay Bhaskar Reddy Gayam is currently practicing as an internist at Interfaith Medical Center in Brooklyn, New York, USA. He is also a Clinical Assistant Professor at the SUNY Downstate University Hospital and Adjunct Professor of Medicine at the American University of Antigua. He is a holder of an M.B.B.S. degree bestowed to him by Osmania Medical College and received his M.D. at Interfaith Medical Center. His career goals thus far have heavily focused on direct patient care, medical education, and clinical research. He currently serves in two leadership capacities; Assistant Program Director of Medicine at Interfaith Medical Center and as a Councilor for the American\r\nFederation for Medical Research. As a true academician and researcher, he has more than 50 papers indexed in international peer-reviewed journals. He has also presented numerous papers in multiple national and international scientific conferences. His areas of research interest include general internal medicine, gastroenterology and hepatology. He serves as an editor, editorial board member and reviewer for multiple international journals. His research on Hepatitis C has been very successful and has led to multiple research awards, including the 'Equity in Prevention and Treatment Award” from the New York Department of Health Viral Hepatitis Symposium (2018) and the 'Presidential Poster Award” awarded to him by the American College of Gastroenterology (2018). He was also awarded 'Outstanding Clinician in General Medicine” by Venus International Foundation for his extensive research expertise and services, perform over and above the standard expected in the advancement of healthcare, patient safety and quality of care.",institutionString:"Interfaith Medical Center",institution:{name:"Interfaith Medical Center",country:{name:"United States of America"}}},{id:"93517",title:"Dr.",name:"Clement",middleName:"Adebajo",surname:"Meseko",slug:"clement-meseko",fullName:"Clement Meseko",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/93517/images/system/93517.jpg",biography:"Dr. Clement Meseko obtained DVM and PhD degree in Veterinary Medicine and Virology respectively. He has worked for over 20 years in both private and public sectors including the academia, contributing to knowledge and control of infectious disease. Through the application of epidemiological skill, classical and molecular virological skills, he investigates viruses of economic and public health importance for the mitigation of the negative impact on people, animal and the environment in the context of Onehealth. \r\nDr. Meseko’s field experience on animal and zoonotic diseases and pathogen dynamics at the human-animal interface over the years shaped his carrier in research and scientific inquiries. He has been part of the investigation of Highly Pathogenic Avian Influenza incursions in sub Saharan Africa and monitors swine Influenza (Pandemic influenza Virus) agro-ecology and potential for interspecies transmission. He has authored and reviewed a number of journal articles and book chapters.",institutionString:"National Veterinary Research Institute",institution:{name:"National Veterinary Research Institute",country:{name:"Nigeria"}}},{id:"158026",title:"Prof.",name:"Shailendra K.",middleName:null,surname:"Saxena",slug:"shailendra-k.-saxena",fullName:"Shailendra K. Saxena",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRET3QAO/Profile_Picture_2022-05-10T10:10:26.jpeg",biography:"Professor Dr. Shailendra K. Saxena is a vice dean and professor at King George's Medical University, Lucknow, India. His research interests involve understanding the molecular mechanisms of host defense during human viral infections and developing new predictive, preventive, and therapeutic strategies for them using Japanese encephalitis virus (JEV), HIV, and emerging viruses as a model via stem cell and cell culture technologies. His research work has been published in various high-impact factor journals (Science, PNAS, Nature Medicine) with a high number of citations. He has received many awards and honors in India and abroad including various Young Scientist Awards, BBSRC India Partnering Award, and Dr. JC Bose National Award of Department of Biotechnology, Min. of Science and Technology, Govt. of India. Dr. Saxena is a fellow of various international societies/academies including the Royal College of Pathologists, United Kingdom; Royal Society of Medicine, London; Royal Society of Biology, United Kingdom; Royal Society of Chemistry, London; and Academy of Translational Medicine Professionals, Austria. He was named a Global Leader in Science by The Scientist. He is also an international opinion leader/expert in vaccination for Japanese encephalitis by IPIC (UK).",institutionString:"King George's Medical University",institution:{name:"King George's Medical University",country:{name:"India"}}},{id:"94928",title:"Dr.",name:"Takuo",middleName:null,surname:"Mizukami",slug:"takuo-mizukami",fullName:"Takuo Mizukami",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/94928/images/6402_n.jpg",biography:null,institutionString:null,institution:{name:"National Institute of Infectious Diseases",country:{name:"Japan"}}},{id:"233433",title:"Dr.",name:"Yulia",middleName:null,surname:"Desheva",slug:"yulia-desheva",fullName:"Yulia Desheva",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/233433/images/system/233433.png",biography:"Dr. Yulia Desheva is a leading researcher at the Institute of Experimental Medicine, St. Petersburg, Russia. She is a professor in the Stomatology Faculty, St. Petersburg State University. She has expertise in the development and evaluation of a wide range of live mucosal vaccines against influenza and bacterial complications. Her research interests include immunity against influenza and COVID-19 and the development of immunization schemes for high-risk individuals.",institutionString:'Federal State Budgetary Scientific Institution "Institute of Experimental Medicine"',institution:null},{id:"238958",title:"Mr.",name:"Atamjit",middleName:null,surname:"Singh",slug:"atamjit-singh",fullName:"Atamjit Singh",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/238958/images/6575_n.jpg",biography:null,institutionString:null,institution:null},{id:"333753",title:"Dr.",name:"Rais",middleName:null,surname:"Ahmed",slug:"rais-ahmed",fullName:"Rais Ahmed",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/333753/images/20168_n.jpg",biography:null,institutionString:null,institution:null},{id:"252058",title:"M.Sc.",name:"Juan",middleName:null,surname:"Sulca",slug:"juan-sulca",fullName:"Juan Sulca",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/252058/images/12834_n.jpg",biography:null,institutionString:null,institution:null},{id:"191392",title:"Dr.",name:"Marimuthu",middleName:null,surname:"Govindarajan",slug:"marimuthu-govindarajan",fullName:"Marimuthu Govindarajan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/191392/images/5828_n.jpg",biography:"Dr. M. Govindarajan completed his BSc degree in Zoology at Government Arts College (Autonomous), Kumbakonam, and MSc, MPhil, and PhD degrees at Annamalai University, Annamalai Nagar, Tamil Nadu, India. He is serving as an assistant professor at the Department of Zoology, Annamalai University. His research interests include isolation, identification, and characterization of biologically active molecules from plants and microbes. He has identified more than 20 pure compounds with high mosquitocidal activity and also conducted high-quality research on photochemistry and nanosynthesis. He has published more than 150 studies in journals with impact factor and 2 books in Lambert Academic Publishing, Germany. He serves as an editorial board member in various national and international scientific journals.",institutionString:null,institution:null},{id:"274660",title:"Dr.",name:"Damodar",middleName:null,surname:"Paudel",slug:"damodar-paudel",fullName:"Damodar Paudel",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/274660/images/8176_n.jpg",biography:"I am DrDamodar Paudel,currently working as consultant Physician in Nepal police Hospital.",institutionString:null,institution:null},{id:"241562",title:"Dr.",name:"Melvin",middleName:null,surname:"Sanicas",slug:"melvin-sanicas",fullName:"Melvin Sanicas",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/241562/images/6699_n.jpg",biography:null,institutionString:null,institution:null},{id:"337446",title:"Dr.",name:"Maria",middleName:null,surname:"Zavala-Colon",slug:"maria-zavala-colon",fullName:"Maria Zavala-Colon",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Puerto Rico, Medical Sciences Campus",country:{name:"United States of America"}}},{id:"338856",title:"Mrs.",name:"Nur Alvira",middleName:null,surname:"Pascawati",slug:"nur-alvira-pascawati",fullName:"Nur Alvira Pascawati",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Universitas Respati Yogyakarta",country:{name:"Indonesia"}}},{id:"441116",title:"Dr.",name:"Jovanka M.",middleName:null,surname:"Voyich",slug:"jovanka-m.-voyich",fullName:"Jovanka M. Voyich",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Montana State University",country:{name:"United States of America"}}},{id:"330412",title:"Dr.",name:"Muhammad",middleName:null,surname:"Farhab",slug:"muhammad-farhab",fullName:"Muhammad Farhab",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Agriculture Faisalabad",country:{name:"Pakistan"}}},{id:"349495",title:"Dr.",name:"Muhammad",middleName:null,surname:"Ijaz",slug:"muhammad-ijaz",fullName:"Muhammad Ijaz",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Veterinary and Animal Sciences",country:{name:"Pakistan"}}}]}},subseries:{item:{id:"4",type:"subseries",title:"Fungal Infectious Diseases",keywords:"Emerging Fungal Pathogens, Invasive Infections, Epidemiology, Cell Membrane, Fungal Virulence, Diagnosis, Treatment",scope:"Fungi are ubiquitous and there are almost no non-pathogenic fungi. Fungal infectious illness prevalence and prognosis are determined by the exposure between fungi and host, host immunological state, fungal virulence, and early and accurate diagnosis and treatment. \r\nPatients with both congenital and acquired immunodeficiency are more likely to be infected with opportunistic mycosis. Fungal infectious disease outbreaks are common during the post- disaster rebuilding era, which is characterised by high population density, migration, and poor health and medical conditions.\r\nSystemic or local fungal infection is mainly associated with the fungi directly inhaled or inoculated in the environment during the disaster. The most common fungal infection pathways are human to human (anthropophilic), animal to human (zoophilic), and environment to human (soilophile). Diseases are common as a result of widespread exposure to pathogenic fungus dispersed into the environment. \r\nFungi that are both common and emerging are intertwined. In Southeast Asia, for example, Talaromyces marneffei is an important pathogenic thermally dimorphic fungus that causes systemic mycosis. Widespread fungal infections with complicated and variable clinical manifestations, such as Candida auris infection resistant to several antifungal medicines, Covid-19 associated with Trichoderma, and terbinafine resistant dermatophytosis in India, are among the most serious disorders. \r\nInappropriate local or systemic use of glucocorticoids, as well as their immunosuppressive effects, may lead to changes in fungal infection spectrum and clinical characteristics. Hematogenous candidiasis is a worrisome issue that affects people all over the world, particularly ICU patients. CARD9 deficiency and fungal infection have been major issues in recent years. Invasive aspergillosis is associated with a significant death rate. Special attention should be given to endemic fungal infections, identification of important clinical fungal infections advanced in yeasts, filamentous fungal infections, skin mycobiome and fungal genomes, and immunity to fungal infections.\r\nIn addition, endemic fungal diseases or uncommon fungal infections caused by Mucor irregularis, dermatophytosis, Malassezia, cryptococcosis, chromoblastomycosis, coccidiosis, blastomycosis, histoplasmosis, sporotrichosis, and other fungi, should be monitored. \r\nThis topic includes the research progress on the etiology and pathogenesis of fungal infections, new methods of isolation and identification, rapid detection, drug sensitivity testing, new antifungal drugs, schemes and case series reports. It will provide significant opportunities and support for scientists, clinical doctors, mycologists, antifungal drug researchers, public health practitioners, and epidemiologists from all over the world to share new research, ideas and solutions to promote the development and progress of medical mycology.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/4.jpg",hasOnlineFirst:!0,hasPublishedBooks:!1,annualVolume:11400,editor:{id:"174134",title:"Dr.",name:"Yuping",middleName:null,surname:"Ran",slug:"yuping-ran",fullName:"Yuping Ran",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bS9d6QAC/Profile_Picture_1630330675373",biography:"Dr. Yuping Ran, Professor, Department of Dermatology, West China Hospital, Sichuan University, Chengdu, China. Completed the Course Medical Mycology, the Centraalbureau voor Schimmelcultures (CBS), Fungal Biodiversity Centre, Netherlands (2006). International Union of Microbiological Societies (IUMS) Fellow, and International Emerging Infectious Diseases (IEID) Fellow, Centers for Diseases Control and Prevention (CDC), Atlanta, USA. Diploma of Dermatological Scientist, Japanese Society for Investigative Dermatology. Ph.D. of Juntendo University, Japan. Bachelor’s and Master’s degree, Medicine, West China University of Medical Sciences. Chair of Sichuan Medical Association Dermatology Committee. General Secretary of The 19th Annual Meeting of Chinese Society of Dermatology and the Asia Pacific Society for Medical Mycology (2013). In charge of the Annual Medical Mycology Course over 20-years authorized by National Continue Medical Education Committee of China. Member of the board of directors of the Asia-Pacific Society for Medical Mycology (APSMM). Associate editor of Mycopathologia. Vice-chief of the editorial board of Chinses Journal of Mycology, China. Board Member and Chair of Mycology Group of Chinese Society of Dermatology.",institutionString:null,institution:{name:"Sichuan University",institutionURL:null,country:{name:"China"}}},editorTwo:null,editorThree:null,series:{id:"6",title:"Infectious Diseases",doi:"10.5772/intechopen.71852",issn:"2631-6188"},editorialBoard:[{id:"302145",title:"Dr.",name:"Felix",middleName:null,surname:"Bongomin",slug:"felix-bongomin",fullName:"Felix Bongomin",profilePictureURL:"https://mts.intechopen.com/storage/users/302145/images/system/302145.jpg",institutionString:null,institution:{name:"Gulu University",institutionURL:null,country:{name:"Uganda"}}},{id:"45803",title:"Ph.D.",name:"Payam",middleName:null,surname:"Behzadi",slug:"payam-behzadi",fullName:"Payam Behzadi",profilePictureURL:"https://mts.intechopen.com/storage/users/45803/images/system/45803.jpg",institutionString:"Islamic Azad University, Tehran",institution:{name:"Islamic Azad University, Tehran",institutionURL:null,country:{name:"Iran"}}}]},onlineFirstChapters:{paginationCount:13,paginationItems:[{id:"82457",title:"Canine Hearing Management",doi:"10.5772/intechopen.105515",signatures:"Peter M. Skip Scheifele, Devan Marshall, Stephen Lee, Paul Reid, Thomas McCreery and David Byrne",slug:"canine-hearing-management",totalDownloads:3,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Recent Advances in Canine Medicine",coverURL:"https://cdn.intechopen.com/books/images_new/11580.jpg",subseries:{id:"19",title:"Animal Science"}}},{id:"82285",title:"Parvovirus Vectors: The Future of Gene Therapy",doi:"10.5772/intechopen.105085",signatures:"Megha Gupta",slug:"parvovirus-vectors-the-future-of-gene-therapy",totalDownloads:6,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Recent Advances in Canine Medicine",coverURL:"https://cdn.intechopen.com/books/images_new/11580.jpg",subseries:{id:"19",title:"Animal Science"}}},{id:"81793",title:"Canine parvovirus-2: An Emerging Threat to Young Pets",doi:"10.5772/intechopen.104846",signatures:"Mithilesh Singh, Rajendran Manikandan, Ujjwal Kumar De, Vishal Chander, Babul Rudra Paul, Saravanan Ramakrishnan and Darshini Maramreddy",slug:"canine-parvovirus-2-an-emerging-threat-to-young-pets",totalDownloads:19,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Recent Advances in Canine Medicine",coverURL:"https://cdn.intechopen.com/books/images_new/11580.jpg",subseries:{id:"19",title:"Animal Science"}}},{id:"81271",title:"The Diversity of Parvovirus Telomeres",doi:"10.5772/intechopen.102684",signatures:"Marianne Laugel, Emilie Lecomte, Eduard Ayuso, Oumeya Adjali, Mathieu Mével and Magalie Penaud-Budloo",slug:"the-diversity-of-parvovirus-telomeres",totalDownloads:38,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Recent Advances in Canine Medicine",coverURL:"https://cdn.intechopen.com/books/images_new/11580.jpg",subseries:{id:"19",title:"Animal Science"}}},{id:"79209",title:"Virtual Physiology: A Tool for the 21st Century",doi:"10.5772/intechopen.99671",signatures:"Carmen Nóbrega, Maria Aires Pereira, Catarina Coelho, Isabel Brás, Ana Cristina Mega, Carla Santos, Fernando Esteves, Rita Cruz, Ana I. Faustino-Rocha, Paula A. Oliveira, João Mesquita and Helena Vala",slug:"virtual-physiology-a-tool-for-the-21st-century",totalDownloads:153,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Updates on Veterinary Anatomy and Physiology",coverURL:"https://cdn.intechopen.com/books/images_new/10665.jpg",subseries:{id:"19",title:"Animal Science"}}},{id:"78543",title:"Pulmonary Vein: Embryology, Anatomy, Function and Disease",doi:"10.5772/intechopen.100051",signatures:"Chan I-Ping and Hsueh Tung",slug:"pulmonary-vein-embryology-anatomy-function-and-disease",totalDownloads:183,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Updates on Veterinary Anatomy and Physiology",coverURL:"https://cdn.intechopen.com/books/images_new/10665.jpg",subseries:{id:"19",title:"Animal Science"}}},{id:"78564",title:"Anatomy of the Rhesus Monkey (Macaca mulatta): The Essentials for the Biomedical Researcher",doi:"10.5772/intechopen.99067",signatures:"Christophe Casteleyn and Jaco Bakker",slug:"anatomy-of-the-rhesus-monkey-macaca-mulatta-the-essentials-for-the-biomedical-researcher",totalDownloads:349,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Updates on Veterinary Anatomy and Physiology",coverURL:"https://cdn.intechopen.com/books/images_new/10665.jpg",subseries:{id:"19",title:"Animal Science"}}},{id:"77999",title:"Bronchus-Associated Lymphoid Tissue (BALT) Histology and Its Role in Various Pathologies",doi:"10.5772/intechopen.99366",signatures:"Tuba Parlak Ak",slug:"bronchus-associated-lymphoid-tissue-balt-histology-and-its-role-in-various-pathologies",totalDownloads:212,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Updates on Veterinary Anatomy and Physiology",coverURL:"https://cdn.intechopen.com/books/images_new/10665.jpg",subseries:{id:"19",title:"Animal Science"}}},{id:"78242",title:"Genomic Instability and Cyto-Genotoxic Damage in Animal Species",doi:"10.5772/intechopen.99685",signatures:"María Evarista Arellano-García, Olivia Torres-Bugarín, Maritza Roxana García-García, Daniel García-Flores, Yanis Toledano-Magaña, Cinthya Sofia Sanabria-Mora, Sandra Castro-Gamboa and Juan Carlos García-Ramos",slug:"genomic-instability-and-cyto-genotoxic-damage-in-animal-species",totalDownloads:150,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Updates on Veterinary Anatomy and Physiology",coverURL:"https://cdn.intechopen.com/books/images_new/10665.jpg",subseries:{id:"19",title:"Animal Science"}}},{id:"78503",title:"Biomechanics of the Canine Elbow Joint",doi:"10.5772/intechopen.99569",signatures:"Thomas Rohwedder",slug:"biomechanics-of-the-canine-elbow-joint",totalDownloads:180,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Updates on Veterinary Anatomy and Physiology",coverURL:"https://cdn.intechopen.com/books/images_new/10665.jpg",subseries:{id:"19",title:"Animal Science"}}},{id:"78018",title:"Application of Noble Metals in the Advances in Animal Disease Diagnostics",doi:"10.5772/intechopen.99162",signatures:"Gabriel Alexis S.P. Tubalinal, Leonard Paulo G. Lucero, Jim Andreus V. Mangahas, Marvin A. Villanueva and Claro N. Mingala",slug:"application-of-noble-metals-in-the-advances-in-animal-disease-diagnostics",totalDownloads:111,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Updates on Veterinary Anatomy and Physiology",coverURL:"https://cdn.intechopen.com/books/images_new/10665.jpg",subseries:{id:"19",title:"Animal Science"}}},{id:"77455",title:"Marek’s Disease Is a Threat for Large Scale Poultry Production",doi:"10.5772/intechopen.98939",signatures:"Wojciech Kozdruń, Jowita Samanta Niczyporuk and Natalia Styś-Fijoł",slug:"marek-s-disease-is-a-threat-for-large-scale-poultry-production",totalDownloads:261,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Updates on Veterinary Anatomy and Physiology",coverURL:"https://cdn.intechopen.com/books/images_new/10665.jpg",subseries:{id:"19",title:"Animal Science"}}},{id:"74655",title:"Taxon-Specific Pair Bonding in Gibbons (Hylobatidae)",doi:"10.5772/intechopen.95270",signatures:"Thomas Geissmann, Simone Rosenkranz-Weck, Judith J.G.M. Van Der Loo and Mathias Orgeldinger",slug:"taxon-specific-pair-bonding-in-gibbons-hylobatidae",totalDownloads:398,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Updates on Veterinary Anatomy and Physiology",coverURL:"https://cdn.intechopen.com/books/images_new/10665.jpg",subseries:{id:"19",title:"Animal Science"}}}]},publishedBooks:{paginationCount:1,paginationItems:[{type:"book",id:"10843",title:"Persistent Organic Pollutants (POPs)",subtitle:"Monitoring, Impact and Treatment",coverURL:"https://cdn.intechopen.com/books/images_new/10843.jpg",slug:"persistent-organic-pollutants-pops-monitoring-impact-and-treatment",publishedDate:"April 13th 2022",editedByType:"Edited by",bookSignature:"Mohamed Nageeb Rashed",hash:"f5b1589f0a990b6114fef2dadc735dd9",volumeInSeries:1,fullTitle:"Persistent Organic Pollutants (POPs) - Monitoring, Impact and Treatment",editors:[{id:"63465",title:"Prof.",name:"Mohamed Nageeb",middleName:null,surname:"Rashed",slug:"mohamed-nageeb-rashed",fullName:"Mohamed Nageeb Rashed",profilePictureURL:"https://mts.intechopen.com/storage/users/63465/images/system/63465.gif",institutionString:null,institution:{name:"Aswan University",institutionURL:null,country:{name:"Egypt"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null}]},testimonialsList:[{id:"27",text:"The opportunity to work with a prestigious publisher allows for the possibility to collaborate with more research groups interested in animal nutrition, leading to the development of new feeding strategies and food valuation while being more sustainable with the environment, allowing more readers to learn about the subject.",author:{id:"175967",name:"Manuel",surname:"Gonzalez Ronquillo",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/175967/images/system/175967.png",slug:"manuel-gonzalez-ronquillo",institution:{id:"6221",name:"Universidad Autónoma del Estado de México",country:{id:null,name:"Mexico"}}}},{id:"18",text:"It was great publishing with IntechOpen, the process was straightforward and I had support all along.",author:{id:"71579",name:"Berend",surname:"Olivier",institutionString:"Utrecht University",profilePictureURL:"https://mts.intechopen.com/storage/users/71579/images/system/71579.png",slug:"berend-olivier",institution:{id:"253",name:"Utrecht University",country:{id:null,name:"Netherlands"}}}},{id:"8",text:"I work with IntechOpen for a number of reasons: their professionalism, their mission in support of Open Access publishing, and the quality of their peer-reviewed publications, but also because they believe in equality.",author:{id:"202192",name:"Catrin",surname:"Rutland",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/202192/images/system/202192.png",slug:"catrin-rutland",institution:{id:"134",name:"University of Nottingham",country:{id:null,name:"United Kingdom"}}}}]},submityourwork:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:9,numberOfPublishedChapters:89,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:104,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:32,numberOfPublishedChapters:318,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:12,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:11,numberOfPublishedChapters:141,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:8,numberOfPublishedChapters:129,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!0},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:113,numberOfOpenTopics:3,numberOfUpcomingTopics:1,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:11,numberOfPublishedChapters:106,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2753-894X",doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:5,numberOfOpenTopics:1,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!0},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:0,numberOfPublishedChapters:15,numberOfOpenTopics:5,numberOfUpcomingTopics:0,issn:null,doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],subseriesList:[{id:"14",title:"Cell and Molecular Biology",scope:"The Cell and Molecular Biology topic within the IntechOpen Biochemistry Series aims to rapidly publish contributions on all aspects of cell and molecular biology, including aspects related to biochemical and genetic research (not only in humans but all living beings). We encourage the submission of manuscripts that provide novel and mechanistic insights that report significant advances in the fields. Topics include, but are not limited to: Advanced techniques of cellular and molecular biology (Molecular methodologies, imaging techniques, and bioinformatics); Biological activities at the molecular level; Biological processes of cell functions, cell division, senescence, maintenance, and cell death; Biomolecules interactions; Cancer; Cell biology; Chemical biology; Computational biology; Cytochemistry; Developmental biology; Disease mechanisms and therapeutics; DNA, and RNA metabolism; Gene functions, genetics, and genomics; Genetics; Immunology; Medical microbiology; Molecular biology; Molecular genetics; Molecular processes of cell and organelle dynamics; Neuroscience; Protein biosynthesis, degradation, and functions; Regulation of molecular interactions in a cell; Signalling networks and system biology; Structural biology; Virology and microbiology.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/14.jpg",keywords:"Omics (Transcriptomics; Proteomics; Metabolomics), Molecular Biology, Cell Biology, Signal Transduction and Regulation, Cell Growth and Differentiation, Apoptosis, Necroptosis, Ferroptosis, Autophagy, Cell Cycle, Macromolecules and Complexes, Gene Expression"},{id:"15",title:"Chemical Biology",scope:"Chemical biology spans the fields of chemistry and biology involving the application of biological and chemical molecules and techniques. In recent years, the application of chemistry to biological molecules has gained significant interest in medicinal and pharmacological studies. This topic will be devoted to understanding the interplay between biomolecules and chemical compounds, their structure and function, and their potential applications in related fields. Being a part of the biochemistry discipline, the ideas and concepts that have emerged from Chemical Biology have affected other related areas. This topic will closely deal with all emerging trends in this discipline.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/15.jpg",keywords:"Phenolic Compounds, Essential Oils, Modification of Biomolecules, Glycobiology, Combinatorial Chemistry, Therapeutic peptides, Enzyme Inhibitors"},{id:"17",title:"Metabolism",scope:"Metabolism is frequently defined in biochemistry textbooks as the overall process that allows living systems to acquire and use the free energy they need for their vital functions or the chemical processes that occur within a living organism to maintain life. Behind these definitions are hidden all the aspects of normal and pathological functioning of all processes that the topic ‘Metabolism’ will cover within the Biochemistry Series. Thus all studies on metabolism will be considered for publication.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/17.jpg",keywords:"Biomolecules Metabolism, Energy Metabolism, Metabolic Pathways, Key Metabolic Enzymes, Metabolic Adaptation"},{id:"18",title:"Proteomics",scope:"With the recognition that the human genome cannot provide answers to the etiology of a disorder, changes in the proteins expressed by a genome became a focus in research. Thus proteomics, an area of research that detects all protein forms expressed in an organism, including splice isoforms and post-translational modifications, is more suitable than genomics for a comprehensive understanding of the biochemical processes that govern life. The most common proteomics applications are currently in the clinical field for the identification, in a variety of biological matrices, of biomarkers for diagnosis and therapeutic intervention of disorders. From the comparison of proteomic profiles of control and disease or different physiological states, which may emerge, changes in protein expression can provide new insights into the roles played by some proteins in human pathologies. Understanding how proteins function and interact with each other is another goal of proteomics that makes this approach even more intriguing. Specialized technology and expertise are required to assess the proteome of any biological sample. Currently, proteomics relies mainly on mass spectrometry (MS) combined with electrophoretic (1 or 2-DE-MS) and/or chromatographic techniques (LC-MS/MS). MS is an excellent tool that has gained popularity in proteomics because of its ability to gather a complex body of information such as cataloging protein expression, identifying protein modification sites, and defining protein interactions. The Proteomics topic aims to attract contributions on all aspects of MS-based proteomics that, by pushing the boundaries of MS capabilities, may address biological problems that have not been resolved yet.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/18.jpg",keywords:"Mono- and Two-Dimensional Gel Electrophoresis (1-and 2-DE), Liquid Chromatography (LC), Mass Spectrometry/Tandem Mass Spectrometry (MS; MS/MS), Proteins"}],annualVolumeBook:{},thematicCollection:[],selectedSeries:null,selectedSubseries:null},seriesLanding:{item:null},libraryRecommendation:{success:null,errors:{},institutions:[]},route:{name:"profile.detail",path:"/profiles/122534",hash:"",query:{},params:{id:"122534"},fullPath:"/profiles/122534",meta:{},from:{name:null,path:"/",hash:"",query:{},params:{},fullPath:"/",meta:{}}}},function(){var e;(e=document.currentScript||document.scripts[document.scripts.length-1]).parentNode.removeChild(e)}()