Weibo Cai

Dr Weibo Cai received his BS degree from Nanjing University in 1995 and a PhD degree in Chemistry from UCSD in 2004. After three years of post-doctoral training at the Molecular Imaging Program at Stanford University, he joined the University of Wisconsin - Madison as a Biomedical Engineering Cluster Hire in February 2008 and is currently an Assistant Professor with joint appointment in the Departments of Radiology and Medical Physics. Prof Cai has authored > 90 peer-reviewed articles which have been cited > 3,100 times (H-index: 29). Prof Cai has won many prestigious awards and served on the Editorial Board of 18 scientific journals. He is currently the Executive Editor of the American Journal of Nuclear Medicine and Molecular Imaging.

1books edited

1chapters authored

Latest work with IntechOpen by Weibo Cai

Proteins are indispensable players in virtually all biological events. The functions of proteins are coordinated through intricate regulatory networks of transient protein-protein interactions (PPIs). To predict and/or study PPIs, a wide variety of techniques have been developed over the last several decades. Many in vitro and in vivo assays have been implemented to explore the mechanism of these ubiquitous interactions. However, despite significant advances in these experimental approaches, many limitations exist such as false-positives/false-negatives, difficulty in obtaining crystal structures of proteins, challenges in the detection of transient PPI, among others. To overcome these limitations, many computational approaches have been developed which are becoming increasingly widely used to facilitate the investigation of PPIs. This book has gathered an ensemble of experts in the field, in 22 chapters, which have been broadly categorized into Computational Approaches, Experimental Approaches, and Others.

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