Bibo Li

Dr. Bibo Li obtained her Ph.D. in Molecular Biology from Weill Cornell Medical College in 1997 and did her postdoctoral training working on telomere functions in humans. In 2002, Dr. Li started to study the telomere structure and functions in a protozoan parasite, Trypanosoma brucei, which causes human African trypanosomiasis. Dr. Li joined Cleveland State University in 2006 and became a tenured associate professor in 2011. Her work has led to the identification of T. brucei telomere proteins TRF and RAP1. She has shown that T. brucei RAP1 plays an essential role in silencing virulence genes located adjacent to telomeres, demonstrating for the first time that the telomere complex plays an important role in T. brucei pathogenesis and virulence regulation (Yang et al. 2009. Cell, as a cover story)

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Latest work with IntechOpen by Bibo Li

Telomeres, located at the ends of linear chromosomes, are essential for genome stability and integrity. Advances in telomere researches have linked telomere dysfunction with cellular aging and a number of age-related human diseases. Recent studies further expanded our knowledge of telomere functions - telomeres are shown to be important for microbial pathogen virulence and telomere proteins have important non-telomeric cellular functions. This book includes current opinions on selected aspects of telomere research and their implication, in hope to help us focus better on future studies and enhance our research progress.

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