David Lapota

Space and Naval Warfare Systems Center PacificUnited States of America

• Dr. Lapota is the US Navy’s leading scientist in bioluminescence research activities and developer of bioluminescence measurement systems and has worked at the Space and Naval Warfare Systems Center, Pacific for 33 years. His academic credentials include a Ph.D. in Biology from University of California, Santa Barbara, an M.A. in Geography and B.S in Zoology from San Diego State University. His accomplishments include more than 30 published manuscripts in the open literature, 37 symposia presentations, 22 oceanographic expeditions, and 10 US Navy patents in bioluminescence instrumentation. Dr. Lapota was also awarded two Exemplary Achievement Awards and the Outstanding Technology Transfer Professional Award from the Federal Laboratory Consortium, for the Qwiklite 200, from Department of Defense in 2008 at SSC PACIFIC. Dr. Lapota is also a member of the American Geophysical Union (Ocean Sciences Member 1981- present) Washington, D.C.; American Society of testing and Materials (Committee E47 - Biological Effects); The Explorers Club, Fellow National (Elected 1989), and the Marine Technology Society.

1books edited

2chapters authored

Latest work with IntechOpen by David Lapota

We now find ourselves utilizing luciferase - luciferin proteins, ATP, genes and the whole complex of these interactions to observe and follow the progress or inhibition of tumors in animal models by measuring bioluminescence intensity, spatially and temporally using highly sophisticated camera systems. This book describes applications in preclinical oncology research by bioluminescence imaging (BLI) with a variety of applications. Chapters describe current methodologies for rapid detection of contaminants using the Milliflex system, and the use of bioluminescence resonance energy transfer (BRET) technology for monitoring physical interactions between proteins in living cells. Others are using bioluminescent proteins for high sensitive optical reporters imaging in living animals, developing pH-tolerant luciferase for brighter in vivo imaging, and oscillation characteristics in bacterial bioluminescence. The book also contains descriptions of the long-term seasonal characteristics of oceanic bioluminescence and the responsible planktonic species producing bioluminescence. Such studies are few and rare.

Go to the book