Angabin Matin

Dr. Angabin Matin is an Associate Professor in the Department of Genetics at MD Anderson Cancer Center in Houston, Texas. She received her Bachelor and Master of Science degrees from the University of Singapore. She obtained her Ph.D. in 1993 in Cancer Biology from the Graduate School of Biomedical Sciences at Houston, University of Texas, USA. Her current research focuses on using mouse models to dissect the complex genetic causes underlying testicular germ cell tumor development. Together with collaborators, her laboratory identified that loss of the RNA binding protein, DND1, predisposes mice to develop testicular germ cell tumors. There is growing interest to understand the biological role of DND1, a novel regulator of translation, both in normal germ cells and in germ cell tumors. Her laboratory is also involved in mapping and identifying novel testicular tumor predisposing loci and genes in mice.

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Latest work with IntechOpen by Angabin Matin

The book aims to provide an overview of current knowledge regarding germ cell tumors. It deals with the clinical presentations, treatment modalities, the biology and genetics of germ cell tumors in children and adults. Most chapters are focused on testicular germ cell tumors whose incidence has been increasing in young males. Included are reviews on the pathogenesis, risk factors, diagnosis and treatment regimens applied to precursor, pre-invasive lesions as well as to seminomatous and non-seminomatous germ cell tumors of the testes. In addition, a review is included on the diagnosis and current management options for intracranial germ cell tumors in children. Authors have also contributed articles on the genetics and epigenetics of germ cell tumor development in humans and in the mouse model system. This book will be of interest to scientists, physicians and lay readers wishing to review recent developments in the field of germ cell cancers.

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