Comparison of different robotic simulation software.
\r\n\t• As a consequence of the pandemic spread of obesity, NAFLD is one of the most important causes of liver disease worldwide in adults and children. The large volume of patients sets NAFLD apart from other liver diseases, meaning the major focus of clinical care is discerning those at the highest risk of progressive liver disease
\r\n\t• Because the overweighting in childhood and adolescence is associated with an increased risk of NAFLD later in life, the threshold of liver-related morbidity and/or mortality is reached at a younger age. Patients with NAFLD have a high risk of liver-related morbidity and mortality along with metabolic comorbidities and might place a growing strain on healthcare systems
\r\n\t• Whereas animal studies have demonstrated a potential causal role of gut microbiota in NAFLD, human studies have only just started to describe microbiome signatures in NAFLD.
\r\n\t• Proteobacteria are consistently enriched in steatosis and non-alcoholic steatohepatitis.
\r\n\t• Discrepant microbiome signatures across studies could be linked to the heterogeneity of geographical regions, ethnicity, population characteristics, microbiome sequencing tools, NAFLD diagnostic tools, disease spectrum, drug consumption, and circadian rhythm.
\r\n\t• The composition of the diet, in particular the types of lipids and carbohydrates, have an important role in the progression of NAFLD to NASH and fibrosis
\r\n\t• A complex interplay between the environment (especially diet), host genetics, and the gut microflora is crucial for the development and progression of NAFLD
\r\n\t• Activation of the innate immune system has an essential role in maintaining homeostasis and liver regeneration, as well as disease pathogenesis, acting in a cooperative rather than independent fashion
\r\n\t• Discoveries that characterized the importance of cell death in NAFLD progression triggered the development of novel therapeutic and diagnostic approaches for NAFLD
\r\n\t• Various types of cell death contribute to the development of NAFLD; extensive crosstalk and biochemical cooperation exists between these cell death pathways to drive disease progression
\r\n\t• Chronic hepatic inflammation represents the driving force in the evolution of nonalcoholic steatohepatitis (NASH) to liver fibrosis and/or cirrhosis.
\r\n\t• In both humans and rodents, NASH is characterized by B cell and T cell infiltration of the liver as well as by the presence of circulating antibodies targeting antigens originating from oxidative stress.
\r\n\t• Alterations in regulatory T cell and hepatic dendritic cell homeostasis have a role in triggering immune responses during the progression of NASH.
\r\n\t• While NAFLD progression to non-alcoholic steatohepatitis is becoming the leading cause of end-stage liver failure, the leading causes of death in patients with NAFLD are complications of cardiometabolic disease and a tight relationship exists between NAFLD, insulin resistance, and type II diabetes mellitus.
\r\n\t• A NAFLD has become the most common liver disease globally, yet there are currently no approved therapies and It is likely that developing therapeutics that target both NAFLD and cardiometabolic risk factors might be extremely beneficial.
\r\n\t
Computer simulation has become an important tool in robotic research and development [1]. It provides a modeling and evaluation tool for complex systems that are analytically difficult to deal with. Frequently, a robot is consisted of links, joints, sensors, actuators, controller, and other structural elements which are integrated to form a whole system [2]. Indeed, developing a real robot is very expensive and time-consuming and requires multidiscipline skills. Nevertheless, a rapid prototyping environment for modeling, programming, and simulating robot is provided in robotics simulation software [3]. In computer simulation, developers are able design a robot model and evaluate the model such that it fulfills the designation requirements. This includes to identify the unexpected problems that may rise before the physical robot is realized. To some extent, computer simulation can be used to perform experiment and verify the trajectory planning or the efficacy of implemented control algorithm. On the other hand, for example, in robot painting, computer simulation can be effectively utilized to solve robot programming complexity in design path trajectory by programming off-line instead of performing a lead teach principle [4]. Despite these advantages, computer simulation may have drawbacks, for instance, in computational overhead [5] and loss of flexibility because the simulation is developed for a specific field of application only [6].
\nIn the past, computer simulation in robotics was conducted numerically with complex computation. The simulation is heavily relying on mathematical model where the system model is usually assumed to be in ideal case or in predefined conditions. The results obtained from simulation (i.e., usually represented in numbers or computer graphic display) require further interpretation or analysis. Some of these outdated simulation examples can be found in [7, 8, 9]. However, with advanced existing technologies, computer simulation has been evolved and tends to become more realistic and attractive with 3D visualization. The comparison study between several robot simulators in different fields of robotics from kinematics and dynamics to industrial applications is discussed in [1]. These simulations can be visually observed, and they have features which arouse interest for novice people, engineers, and scientists. Most of the robotic simulations are equipped with physics engines (ODE, Bullet, Havok, or PhysX) for real-time collision and dynamics of rigid bodies. One of the examples is the iCub humanoid robot where ODE physics engine is employed [10]. Nevertheless, different simulation platforms using MATLAB/Simulink can also be used to simulate robots [1]. In addition, there is a robotic simulation software named COSIMIR Robotics that used to simulate Mitsubishi industrial robots. It provides virtual simulation environment for robotics and automation, and it is very useful for education in mechatronics as given in [11]. In COSIMIR Robotics software, users do not need to develop a robot model from scratch—as opposed to other typical robotic simulation studios—because the industrial robot models are already provided in the list.
\nDigitization of manufacturing sector is the next phase of industrialization with the so-called industry revolution 4.0. It was first introduced publicly at Hannover Fair in 2011. It is the convergence of industrial production and information and communication technologies [12]. The paradigm of “I4.0”—for short—is to increase productivity and efficiency with the help of new technologies. However, this term is broader, and so it is difficult to grasp by academia and practitioners because the scope covers the entirety of industrial manufacturing [13]. At present, industry 4.0 is still on the conceptual formation stage, and several countries have set up industry 4.0 standards with different names, as it is called “i40,” “IoT,” or “Made in China 2025,” that is, well known in Germany, the USA, and China, respectively [14].
\nIndustry 4.0 as the new phase of industrial revolution has developed gradually from embedded system to the cyber-physical system (CPS) [14]. CPS is one of the key components of industry 4.0 [15, 16], and it is basically an embedded system that exchanges data in an intelligent network which facilitate smart production [17]. The CPS term was coined around 2006 before the term “industry 4.0” was publicly introduced in 2011. This new industrial paradigm embraces the emerging technologies in robotics where the new approach is required to have some kind of self-organization and to be reconfigurable, adaptable, and flexible. For example, flexible interaction in robotics can be reflected by the development of augment reality (AR) application that augments an industrial robot to perform several tasks in maintenance or cooperative work with humans and robots [18]. Another example is the work toward multi-robot systems with improved energy efficiency, high real-time performance, and lower cost which can be achieved by integrating multi-robot systems with cloud computing and any other emerging technologies [19] (e.g., 5G wireless technology). Thus, the robotics technology is one of the essential drivers for industry 4.0. This technology and several other relevant technologies that associated with industry 4.0 are given in \nFigure 1\n.
\nTechnologies associated with industry 4.0 [
In the last few decades, industrial robots could support human workers with complex and high-precision, repetitive, and dangerous tasks. Some of these repetitive tasks, for example, are paint and sealant applications, welding, assembly, material handling, inspection, and so on. However, this robot was not safe for humans to work side by side. Thus, the robots are usually placed in a cage or in an area where humans must stay away from them. In the era of industry 4.0, the popular robots are intelligent, able to collaborate, flexible, mobile, and connected. Several examples of such robots are Bosch APAS assistant, KUKA LBR iiwa, ABB YuMi, FANUC CR-35iA, MRK Systeme KR 5 SI, and Universal Robots UR5. The importance of collaborative robots is to increase the productivity and efficiency (as demanded in new industrial paradigm) when they work side by side with humans [20]. The deployment of these collaborative robots in the new industrialization era raises the potential for complex human-robot interaction (HRI) to create highly flexible processes by mean of symbiotic human-robot collaborative process [21].
\nThe emerging technologies in robotics have enormous effect on education of people. However, only qualified and highly educated employee will be able to control such technologies, so collaboration between the industry and university should be more intense [23]. For example, a study on the usability and acceptance of an industrial prototype in relation to collaborative robots with humans in [24] has suggested the urgency of adaptation of assistive robot systems. It is well known that the collaborative robots (cobots) are very expensive and they are not easily accessible by common students and researchers, except for those who work in leading research institution or industry. To tackle this problem, developing a robot simulation and using it as a testbed is one of the solutions. With this regard, robot simulation is required to have some similar sensors and actuators as those of existing robots. In current robot simulation studio, those features are embedded in many robotic simulations, that is, utilizing open dynamic engine (ODE). In addition, they are quite popular because of their reliability and performance in collision detection system [25]. Some examples of these robot simulations that are quite popular are, namely, Marilou [26], Gazebo [27], and Webots [28, 29].
\nThis chapter discusses the utilization of robots in the industry which comply with industry 4.0 paradigm. More specifically, we elaborate the new emerging industrial robotics that is so-called collaborative robots. The collaborative robots have made humans and robots work side by side without a safety cage. The application of collaborative robots, for example, in automobile industries, has contributed to smart and intelligent manufacturing which is aligned with industry 4.0 concept. This new industrial revolution’s paradigm is still in progress with some challenges. However, there are several issues with regard collaborative robots as well as its implementation in industry. In a case study, we elaborate a collaborative robot named Baxter robot as a role model of robot application that evolves toward industry 4.0. With the advanced computer technologies, computer simulation has become an essential tool in robot development. Research in the fields of robotics and its control system can be validated and analyzed using robot simulation. Thus, the computer of robotic simulations has given new opportunities with regard the new trends of collaborative robots.
\nRobotics has played an essential role in manufacturing industries for so many years. They are tough, fast, and very accurate to perform specific tasks. In terms of speed and accuracy, robot performance is way much better than human workers. However, those robots have left significant gap because it takes hundreds of hours to program [30]. They are employed mainly for specific tasks that involve dangerous tasks and monotonous operation with great precision. Some of these applications are paint and sealant applications, welding, assembly, material handling, inspection, and so on [31]. In old-fashioned and traditional robot in industries as depicted in \nFigure 2\n, the working space of robots are isolated from human workers because it may harm humans if they work near robots or within the working area of robots. At present, with advanced robotics technologies, humans and robots can work side by side collaboratively. The collaboration between humans and robots is still in primitive way, in the sense that the robot is able to detect collision or foreign object and then a corresponding response is executed, for example, by reducing its speed or stopping immediately. Another collaborative robot such as Baxter robot which is designed as an industrial robot can work very closely with people. However, the precision of this robot is still limited [32], and for now it cannot compete with other popular industrial robots, for example, KUKA, ABB, FANUC, Universal Robots, etc., in terms of repetitive tasks. Nevertheless, the usability of this robot is its suitable application as a robot assistant in which the precision can be tolerated.
\nConventional automation factory using KUKA robotics [
Collaborative robots are also known as cooperative robots, cobots, or robot assistants [30]. They are mechanical devices that provide guidance through the use of servomotors, while a human operator provides motive power [34]. Generally speaking, it can be denoted as a robot that works side by side in a safe way either with another robot or with human workers to complete specific tasks. Thus, safety and productivity are the two important issues and become the main factors for design of robotic collaborative behaviors [35]. In human-robot collaboration, this behavior is related to how robots react when human physical contact occurs during execution. On the other hand, human-robot interaction in the general sense is a study of robotic systems for use by or with humans which concern with understanding, designing, and evaluating robots [36]. In physical human-robot interaction, human safety is the main concern and must be considered when evaluating robot setups in a workspace [37]. This interaction is related to a form of communication whether the robots and humans are positioned near to each other or not. Obviously, this interaction term does not necessarily mean collaborating, but merely how the two parties are communicating or interacting with each other in a certain way, while the other term means working together to achieve shared goals. Although these two terms are different in meaning, the human-robot interaction in fact can be used for collaborating. Thus, human and robot collaboration stands between the lines of manual manufacturing (where humans work manually) and full automation (where robots work independently) [30]. By collaborating between humans and robots (or machine), it is widely known that they become more productive than if each party work individually.
\nCollaborative robots at least have several elements, namely, the ability to detect any object within its work space and then react in order to prevent any collision [30], flexibility and situational task sharing [34], and cooperation on a mutual workplace [34]. These three elements differentiate collaborative robots from traditional robots even though the appearance between those industrial robots is the same. Their structural forms of multi-degree of freedom (multi-DOF) are intended to have the capability of reaching every specific coordinate of their workspace. In the case of task complexity or challenge situation, the collaborative robot tends to have more joints, for example, as given in \nFigures 3\n and \n4\n, that is, ABB YuMi IRB 14000 has 14 joints in total or 7 joints for each arm, while KUKA LBR iiwa has 7 joints, respectively. The structural models are reasonable because collaborative robots are designed to be ergonomic. For robotic system with many joints, the complexity of such control system becomes more difficult. Thus, research in control system for such robot is challenging problem.
\nABB YuMi IRB 14000 [
KUKA LBR iiwa [
The competition to bring up the elements of industry 4.0 is still under way between companies in Asia, Europe, and America [38]. There are two successful robotic implementation in industries that link to industry 4.0, namely, robotic application in automobile factories of BMW and Tesla [14]. In BMW group factory, the autonomous mobile robots are used for smart transport systems in supply logistics, while KUKA collaborative robots are utilized to work side by side with humans, for example, for lifting and positioning heavy components and welding operations [39]. On the other hand, Tesla’s factory also has utilized robots with other technologies in their production lines to support smart and intelligent products [14]. One example is the use of industrial robots for repetitive tasks such as applying an even layer of paint for automobiles. For several types of repetitive tasks, fully automated production with robots is chosen instead of human workers, but for other specific tasks, human workers can not be replaced by robots because humans have skills, knowledge, and intuition. Which tasks that should performed by robots or human workers must be analyzed, otherwise the robot utilization in the industry can lead to production delays [39]. Indeed, robotic technologies must be incorporated with any other emerging technologies to improve efficiency and productivity, but this utilization must be well prepared, properly designed, and carefully implemented for end-to-end production lines.
\nThe collaboration between humans and robots is a new shift in industrial and service robotics as an element of strategy for industry 4.0 [30]. This strategy has a goal to set up a secure environment for human-robot collaboration. The framework for safety in industrial robot collaborative environments can be found in [20] where CPS is currently included as part of recent development in intelligent manufacturing. The use of CPS helps to bring the sharing of workspace for human-robot collaboration. The shared workspace of robots and human workers can be illustrated in \nFigure 5\n in which there are three possible configurations: (a) Isolated workspace where robots must be put in a cage in order to prevent any harm to human workers. (b) Some part of the area is shared among humans and robots. (c) Fully shared workspace where humans and robots work side by side to perform several tasks. In the first scenario, there is no interaction or whatsoever between humans and robots when the robot is in operation, while in the last scenario, the human worker may have contact or interaction with the robot in a safe way. Due to safety issue, the robot in the first scenario can be programmed faster than the robot in the last scenario. Thus, these three different scenarios must be designed and evaluated when they are utilized in industry so that the utilization can yield higher efficiency and productivity. This safety issue was also the subject of investigation for the critical requirements of fenceless implementation in human-robot collaboration, specifically in automotive application where the robotic system can be divided into three levels of complexity [42]. However, the new technology capabilities as suggested in [42] are already realized in collaborative robots that are built today.
\nIllustration of shared human and robot workspace [
The humans and robots in \nFigure 5(a)\n and \n(b)\n are not interacting with each other. On the other hand, in \nFigure 5(c)\n, the interaction at least is limited with physical interaction [43]. Human-robot interaction is related to communication between humans and robots whether it is remote interaction or proximity interaction [36]. The elements of human-robot interaction which consist of task structure and user attribute as discussed in [44] probably can also be investigated for future technology in human-robot collaboration. Although this research discussed in [44] is applied in ASIMO (humanoid robot), the research probably can also be implemented for collaborative robots, for example, Baxter robot and ABB YuMi. Some research have been conducted to incorporate the human-robot interaction with human-robot collaboration to increase the productivity in completion of tasks.
\nOn the other hand, mobile robots have become more compliant with human workers in factory. They work autonomously with self-driving and are able to detect obstacle and be aware of human existence. Some of the examples are KUKA youBot [45], mobile industrial robot (MiR), and OTTO self-driving vehicle (SDV) [46]. \nFigure 6\n shows OTTO 1500 SDV in which the robot is designed to move pellets, racks, and other large payloads through dynamic production environments with the ability to carry maximum load of 1500 kg. The combination between manipulator and mobile robots for one system can also be found in mobile robot KMR iiwa and mobile manipulator robot CHIMERA. Another form of collaboration between humans and robots in industry application for different tasks such as lift assist or hands on payload can be found in iTrolley module system [47].
\nOTTO 1500 self-driving vehicle [
In traditional industrial robots, there are several different modes in programming robots, namely, physical setup, lead through or teach mode, continuous walk-through mode, and software modes [2]. In software mode, there are two different approaches, namely, offline programming and online programming. In offline programming, robot simulation is used and set up in advance, while in online teaching, real robot is employed to generate robot program [48]. On the other hand, in collaborative robots, the user may program collaborative robot using task-level programming software tool which is developed based on robot skill concept [48]. The robot simulation as mentioned in programming real robots is totally different from programming robot in robotic simulation studio such as Marilou. In Marilou, the robot model is developed from scratch, and each joint with actuators and sensors is defined, and then, the controller system is designed and implemented using specified language programming. Thus, the robot programming in robotic simulation studio like Marilou is more flexible for different robot models and applications.
\n\n\nFigure 7\n shows a robot that is the so-called Baxter by Rethink Robotics. It is a semi-humanoid robot with limbs of 7 DOF joints to form a dual-armed robot. This robot is a type of industrial robot with several unique features which include the safety for collaboration with human, user-friendliness, ability to train manually with no programming required, and ability to respond to a dynamic environment [49]. The advantage of collaborative robot such as Baxter is the ability to adapt to circumstances because the robot can be adjusted and applied to different applications by reprogramming the robot quickly. Another latest similar version from Rethink Robotics with only one arm is Sawyer. Baxter and Sawyer are both collaborative robots where they can work side by side with human workers and adapt to real-world variability in semi-structured environments.
\nA collaborative robot: Baxter robot [
Some research have been conducted which involved Baxter robot for various applications and problems. For example, manipulation-based assistive robotics [50], performance assessment for point-to-point motion problem [32], and collaborative manipulation of a deformable sheet between humans and Baxter robots [51]. It is suggested that Baxter robot has a good potential for future robotic applications for home services or industrial applications.
\nAt present, there are many robotic simulation studios in the market for commercial use or noncommercial use license. Marilou Robotics Studio [26] is a commercial program of dynamic simulation that has different license types where the end user can choose according to their needs. It is based on Microsoft Robotics Developer Studio for modeling, programming, and simulating an environment [53]. There are various types of license, namely, home, education, project, and professional license. Similar to other robotic simulations, Marilou Robotics Studio employs open dynamic engine for physics engine. This engine is used for simulating rigid bodies and collision detection algorithm of physical interaction. ODE is basically consisted of collection of C library that encapsulates the physical laws, for example, for handling body contacts, frictions, force, collision, etc.
\nThe phrase “simulation” is associated with computational devices used to obtain knowledge of physical system. “Robotic simulation,” on other hand, has a goal to acquire knowledge on performances of robotic systems [54]. Comparison among the three popular robotic simulations which related to product license and programming languages are given in \nTable 1\n. Indeed, Marilou Robotics Studio is considered as one of the leading simulator packages available today [55]. Furthermore, according to Marilou’s website [26], many research institutes (e.g., KIST, TECNALIA, INTEMPORA, etc.), and industries (e.g., KITECH, EasyRobotics, and WIFIBOT), have used this package for research and development.
\nProduct name | \nProgramming language | \nDeveloper | \nLicense type | \n
---|---|---|---|
Gazebo | \nC++ | \nOpen Source Robotic Foundation | \nFree/open source | \n
Webots | \nC/C++, Java, Python, URBI | \nCyberbotics Inc. | \nPaid/commercial | \n
Marilou | \nC/C++, C++, CLI, C#, J#, Cmex function (MATLAB) | \nanyKode Marilou | \nPaid/commercial | \n
OpenRAVE | \nC++, Python | \nOpenRAVE community | \nFree/open source | \n
OpenHRP3 | \nC++ | \nAIST | \nFree/open source | \n
V-REP | \nLUA | \nCoppelia Robotics | \nPaid/commercial | \n
Comparison of different robotic simulation software.
A robot simulation package like Webots from Cyberbotics has a feature where the code can be implemented directly to a real robot by transferring the code after the simulation is completed, while different robot simulations do not have such feature, for example, Gazebo and Marilou. However, both simulations have similar features where actuators and sensors are already provided and must be defined when the construction of robot body is developed. Unlike Webots or COSIMIR simulation packages where the robots are already provided, Marilou is a more general robot type that can be used for multipurpose robot applications, from mobile robot [56] to humanoid robot [57]. In Marilou, a robot must be designed and constructed in a CAD-like interface that is the so-called Marilou Physical Editor (MPE). All physical dimensions in MPE such as shape or geometry of body, its mass, links (between each body), and location of sensors and actuators that will be attached must be properly designed according to the dimension of proposed robot realization. Once the development of model robot is finished, the user can choose which programming language will be used. In \nTable 1\n, there are several robotic simulations that use open dynamic engine as their physics engine.
\nThe features of Marilou simulation package are shown in \nTable 2\n. Sensors and actuators are embedded in a body of geometry or link. Based on these features, any robot’s structure can be built even for the most complex and difficult robots such as humanoid robot [58] or multi-legged robot [59]. Furthermore, the virtual of real-world environments can also be developed in robotic simulation studio. However, to some extent, different license types may give the user different numbers of geometries, maximal devices, and number of robot instances per computer. The maximum number of instances is 12 robots that can run in one computer simulation. This number of robots can be used, for example, in the case of two teams of robot play soccer.
\nJoint type | \nActuator type | \nSensor/device type | \n
---|---|---|
Ball | \nServomotor | \nForce and torque sensor | \n
Hinge for 1 axis | \nDC motor | \nAccelerometer/gyrometer/gyroscope | \n
Hinge for 2 axes | \nActuating cylinder | \nInfrared | \n
Slider | \nAir pressure force | \nUltrasonic | \n
Slider and hinge | \n\n | Emiter receiver | \n
Piston | \n\n | Absolute compass | \n
Fixed | \n\n | Touch area | \n
Universal | \n\n | GPS | \n
\n | \n | Odometer | \n
\n | \n | Laser range finder | \n
\n | \n | LIDAR | \n
\n | \n | Camera | \n
\n | \n | Panoramic spherical camera | \n
\n | \n | Bumper (force on contact) | \n
Joints and embedded devices provided in Marilou robotics studio.
The general structure of robot simulation such as Marilou simulation studio can be depicted in \nFigure 8\n. It consists of world, robot model, bodies, joints, interface, and client. In Marilou, the interface program, Marilou Open Device Access (MODA), is used to communicate with the client. The client sends data or commands to the robot model to the joint through actuators since the actuator is attached directly to a joint robot. Likewise, the client may receive data from sensors in which the robot is interacting with its environments. Based on this structure, the user may develop a collaborative robot, such as mobile robot, for example, in safety scenario when robots are near to humans. The human can be modeled as a dynamic obstacle. Whether the obstacles are static or dynamic, for example, wall, human, or any objects, the robot must be able to detect those obstacles, predict the movement, and perform the necessary response to prevent any collision.
\nGeneral structure of anyKode Marilou.
Marilou simulation is able to simulate multiple robots in one computer by using MODA (Marilou Open Device Access). MODA is a default Marilou SDK and used to reach every robot at the same computer. It can be used for centralized or distributed architecture. In centralized architecture, all robots are accessed from one application program, while in the distributed architectures, each robot is accessed by different application programs separately. Those robots are considered as a single entity that has its own brain and controller whether they are different robot types or similar ones. To develop such multi-robots, usually a robot model is developed in the physics environment in Marilou. Once the robot model that consists of actuators and sensors is completed, the user may choose centralized controller by connecting all robots to one application program or distributed controller by connecting each robot to different application programs for multi-robot application.
\nHowever, there is limitation for how many robots in distributed architecture can be simulated at the same time in one computer. Marilou has different features for multi-robot simulation depending on the type of license. For example, for professional license, the maximum number of instances that can be running per computer is 12 robots, while for education and project license is 8 robots and 2 robots, respectively. In the context of collaborative robots, human workers can be modeled as a single machine that moves independently and assumed as dynamic obstacle. The development of control algorithm and collaborative robot model can be tested and verified through computer simulation by observing how the robot behaves in dynamic environments or near human workers. This feature may serve to simulate robot-robot collaborations and human-robot collaborations in different scenarios.
\nThe main safety system for human-robot collaboration and the essential sensors as discussed in [20] are feasible if constructed using Marilou simulation, because it has similar devices (actuators and sensors) as given in \nTable 2\n that can be incorporated in developed collaborative robots. These sensors include force and torque sensors, touch area, laser range finder, LIDAR, and bumper where these components can be used for safety in collaborative robots. In a practical example, the feasibility of solving a problem of 3D collision avoidance for safe human and robot coexistence as discussed in [60] can also be possibly implemented in Marilou. This dynamic simulation would be visually more attractive than computer simulation presented in [60].
\nAn empirical application example of Marilou simulation is for developing a simulated wheelchair on a virtual environment in which brain-computer interface is used to command the wheelchair in host computer [61]. Indeed, this work is for research only and has not been applied and implemented for industrial application. Here, the author argues that Marilou simulation is, in fact, reliable enough to be used for research and development. The system developed in [61] is illustrated in \nFigure 9\n where brain-computer interface (BCI2000) [62] is connected to a host computer using UDP data communication protocol to control a simulated wheelchair on virtual environments. In host computer, a C++ program is developed to receive command from BCI2000 operator, and then, through MODA interface, the simulated wheelchair on virtual environment can be controlled.
\nBrain-computer interface and Marilou simulation [
In another practical problem, for example, in human-robot interaction research like in urban search and rescue (USAR) robotics as given in [63], computer simulation can be used as a simulator-based research since the system is relatively simple to model, has high fidelity dynamics for approximating robot’s interaction with its environment using current physics engine, and capability of modern graphic cards to approximate camera video. In USARSim, the camera is attached to a mobile robot in unknown (virtual) environments, and the user can monitor and control the robot remotely through camera feedback [63]. This scenario can be extended to larger problems of related research for simulating a human-robot interaction and human-robot collaboration. Although the simulation in [63] is not developed in Marilou simulation, the components of devices in USARSim can also be found in Marilou simulation, for instance, the camera sensor (as shown in \nTable 2\n). Thus, the development of human-robot interaction in Marilou simulation is feasible.
\nThe robot performance for intended industrial application can be evaluated and analyzed if the similar and accurate model of environments can be captured and designed in simulation. For example, as it is given in \nFigure 10\n, KUKA KR6 robot is placed in a cage for safety reason. This robot can be used for simulating pick-and-place robot tasks, and the users are only concerned with controller design and implementation. Thus, the performance of the robot in specific tasks can be analyzed, for example, to observe the payload, speed response, and accuracy. Of course, the performances of whole dynamic simulation system are depended on sensors used as feedback.
\nKUKA KR6 simulation [
In industry application such as Tesla or BMW, utilizing industrial robots including collaborative robots are still challenging because the robots are not agile enough to keep up the production target [39]. To solve this problem, specific collaborative robot can be developed in computer simulation with real-world simulated environments so that the whole process of production lines can be analyzed and evaluated comprehensively. This means the user can choose which type of robots should be used for specific line of cell to increase productivity, whether it is industrial robot, collaborative robots, or autonomous robots. In spite of the potential advantages of robotic simulation like Marilou to solve real problems, the robot simulation package has limited capability for simulating a large scale of robotic systems running at the same time. This scenario is very important, for example, to simulate robots in automation industry where traditional industrial robot and collaborative robot are existing and used for efficient and productive solution. In fact, this computer simulation of large-scale robots is still rare; unfortunately, this type of simulation can be beneficial toward industry 4.0 paradigm in regard to smart factory and productivity.
\nA humanoid robot is a robot having two legs, two arms, the shape of a human body, a trunk, and a head. Usually, it is associated as the robot with the appearance of a full human body and has the ability to walk, for example, Honda ASIMO, HRP, and HUBO robot. These three examples have similarity with its appearance as well as in mechanical design. The research in humanoid robot was initiated around the 1970s in Japan after the development of “Honda P3” by Honda Motor Co., Ltd. The purpose of this development was to build humanoid robots that can walk stably and mimic how humans walk. Since then, many research groups in humanoid robot pursued developing practical humanoid robot. At that time, Japan and South Korea are probably the leading countries in the research of humanoid robot. However, in literature, it seems the research problems in humanoid robot become broader topics and diverse from control walking, grasping, visual recognition, social interaction, virtual simulation, intelligent robot, and so on, including human-robot collaboration and interaction. Here, the author discusses and highlights humanoid robot toward industry 4.0, in particular human-robot collaboration and human-robot interaction. Other aspects of intelligent robot and virtual robot simulation will be briefly presented.
\nAt present, commonly there are two types of actuators used in humanoid robots: First, motor or servo type with harmonic drives, for example, as in Honda ASIMO [64], DRC-HUBO+ [65], and Valkyrie NASA [66], and second, hydraulic type as in Atlas robot [67] and PETMAN [68]. The significance of the two actuators is very different in the sense that the first group of robots has slower response than the second group. The hydraulic actuator has a greater torque relative to the same size of electric motor, and thus, the robots that use hydraulic system are comparatively free from insufficient joint torque problem, while the robots that use electric motor have some problem with insufficient joint torque [65]. Despite of various actuators being used in humanoid robot, the trend of humanoid robot development is the robot that is lightweight with slim body. This design would make it easier for the robot to maneuver and perform certain tasks.
\nIn industrial application, a semi-humanoid type robot such as Baxter robot is well known as a collaborative robot, and it is used in various industry applications to perform certain tasks. Although this robot is not a full body of a humanoid robot, most of it appears as a human except the fact that the robot has no legs to walk. Indeed, the advantage of full-body humanoid robot is that it can maneuver more easily in a complex terrain. However, in industry application or in other manufacturing industries, the terrain is usually simple with flat terrain, but the obstacles are more complex and dynamic. The general comparison of different robots including humanoid robots is presented in \nTable 3\n. It is given in \nTable 3\n that the humanoid robots are commonly used for research, technology demonstrator for specific tasks, or for human-robot interaction. This shows that the humanoid robots so far are not intended for competing with other robots in industrial applications. The use of semi-humanoid robot for collaborative robots in industrial application is more practical than that of a full body of humanoid robots. In fact, the full-body humanoid type of robot is commonly used for research only so far in order to solve practical engineering problems. For example, DCR-HUBO+ in [69] is used to solve the challenging problems of simple tasks such as debris removal, door opening, and wall breaking in the event of the DARPA competition.
\nRobot name | \nDeveloper/manufacturer | \nRobot type | \nApplication purpose | \n
---|---|---|---|
NAO | \nSoftBank Robotics | \nBipedal humanoid robot | \nResearch, education, and entertainment | \n
Pepper | \nSoftBank Robotics | \nBipedal humanoid robot | \nTechnology demonstrator for social and human interaction | \n
Sanbot robot | \nQihan Technology | \nWheeled humanoid robot | \nRetail, hospitality, education, health care, entertainment, security | \n
Enon robot | \nFujitsu Frontech Ltd. and Fujitsu Lab | \nWheeled humanoid robot | \nPersonal assistant/service robot, technology demonstrator | \n
Toyota Partner Robot | \nToyota | \nBipedal humanoid robot | \nEntertainment | \n
Honda ASIMO | \nHonda | \nBipedal humanoid robot | \nResearch, technology demonstrator | \n
HRP | \nAIST | \nBipedal humanoid robot | \nResearch, technology demonstrator | \n
Atlas | \nBoston Dynamics | \nBipedal humanoid robot | \nSearch and rescue, research | \n
TOPIO | \nTosy Future Robot | \nBipedal humanoid robot | \nTechnology demonstrator | \n
iCUB | \nItalian Institute of Technology | \nBipedal humanoid robot | \nResearch | \n
HUBO, DRC-HUBO+ | \nKAIST | \nBipedal humanoid robot | \nResearch, technology demonstrator | \n
Baxter robot | \nRethink Robotics | \nTwo-armed robot | \nSimple industrial jobs, research and education | \n
KR Quantec | \nKUKA | \nManipulator robot | \nIndustrial application | \n
OTTO self-driving vehicle | \nOTTO Motors | \nAutonomous mobile robot | \nSmart transportation/industrial application | \n
MiR100/200/500 | \nMobile Industrial Robots | \nAutonomous mobile robot | \nIndustrial application | \n
KUKA youBot | \nKUKA | \nMobile manipulator robot | \nResearch, industrial application | \n
FANUC collaborative robot | \nFANUC | \nMobile manipulator robot | \nIndustrial application | \n
Bosch APAS | \nBosch | \nMobile manipulator robot | \nIndustrial application | \n
ABB FlexPicker | \nABB Group | \nParallel Manipulator | \nIndustrial application | \n
FANUC iRPickTool | \nFANUC | \nParallel manipulator | \nIndustrial application | \n
ABB IRB YuMi | \nABB Group | \nRobotic arm | \nIndustrial application | \n
FANUC CR-35iA | \nFANUC | \nRobotic arm | \nIndustrial application | \n
UR10 | \nUniversal Robots | \nRobotic arm | \nIndustrial application | \n
Omron TM Series collaborative robot | \nOmron | \nRobotic arm | \nIndustrial application | \n
LBR iiwa and KR AGILUS | \nKUKA | \nRobotic arm | \nIndustrial application | \n
FANUC SR-3iA/SR-6iA | \nFANUC | \nSCARA robot | \nIndustrial application | \n
ABB IRB | \nABB Group | \nSCARA robot | \nIndustrial application | \n
General comparison of various robots and its applications.
The success of humanoid robot in real-world environments is largely dependent on the ability to interact with both humans and its environments [70] in which the humanoid robot has some form of awareness to the real-world context. Hence, the robot’s perception is a key issue for performing high-level tasks such as understanding and learning human-robot interaction. This perception can be detected from the high-level features of human facial expression and body gestures [71]. The perception systems are proposed in [71], but the variety of robotic software architecture and hardware platforms would make the customized solutions hardly interchangeable and adaptable for different human-robot interaction contexts. Another aspect of learning (in control point of view) for the humanoid robot is, for example, in the situation when the robot is falling to the ground. At this circumstance, the robot must be able to get up immediately with certain self-learning process or automatic learning system. Some of the existing humanoid robots are given in \nFigure 11\n. They are commonly used for research as in human-robot interaction, control methods of bipedal walks, indoor localization, and navigation. Moreover, some of them are also used for education [72], entertainment [73], and for home service.
\nDifferent types of humanoid robots: (a) NAO humanoid, (b) pepper humanoid robot, (c) Sanbot robot, (d) Toyota partner robot, (e) Honda ASIMO, and (f) HUBO humanoid robot.
The Cloud technology is one of the key components in the new industrial paradigm of industry 4.0. In relation to humanoid robot, one of the potential applications of Cloud technology is to provide collective robot learning, that is, robot sharing trajectories, control policies, and outcome [74]. One good practical example of Cloud technology application in humanoid robot is in the development of simulation of humanoid robot to complete certain tasks [75] which is part of the DARPA virtual robotic challenge. In [75], the existing Cloud technology was combined with Gazebo simulator for simulating humanoid robot. This developed robot simulation is not only applied to virtual humanoid robot in action but also to other specific challenging environments that must be handled by the humanoid robot. Another example of robotic simulation in the context of humanoid robots is given in [76] where V-REP robotic simulation was used as a testbed to observe how virtual robots would behave in completing certain tasks from given commands by humans. This research was related to teleoperation method based on human-robot interaction by mimicking human’s movement visually for which Baxter robot would learn the movements. Again, robotic simulation would be a key component in robotic research and development, in particular in the field of humanoid robot. Moreover, this opportunity is due to the new emerging of Cloud computing that can be incorporated with robotic simulation.
\nResearch progress in human-robot collaboration and the application of robot simulations toward industry 4.0 have been discussed in this chapter. The key components of collaborative robot in industrial applications are elaborated with various robot types that exist today. Indeed, the collaborative robots can be designed, modeled, and realized in computer simulation using open dynamic engine such as Marilou AnyKode. This virtual robot can serve as a testbed for different purposes from controller design implementation, robot interactions, to validation of robot in specific environment scenarios. Although existing robot simulation packages are equipped with many actuators and embedded sensors that support for application in collaborative robots, the simulation of collaborative robot is still rare to discuss in literature. Since the practical industrial application of full-body humanoid robot in the industry probably still has a long way to go, thus robot simulations can be a better choice for developing different types of robots for future applications, in particular in areas of human-robot collaboration and human-robot interaction for industrial application and home services. Another opportunity lies in virtual reality of human-robot interaction, implementation of artificial intelligence in virtual robots, and synthesizing control algorithm for different robotic configurations.
\nThe author declares that there are no conflicts of interest in this work. All works from other resources in the article have been cited carefully.
The coronavirus pandemic 2019 (COVID-19) and the 2021 delay of cargo ships along the California coastline illustrated recent challenges facing the supply industry and governments across the globe. Evidence shows that supply and demand challenges in the last years resulted from improper collaboration. The global supply industry saw nearly half a million containers of goods stuck off the coast of Southern California as state seaports operated below optimal capacity due to the coronavirus 2019 (COVID-19). The delay of containers disrupted services and delivery of goods in the United States and globally pre-2021 holiday season. Cargo ships could not return to their ports of origin to drop off or pick up more goods while customers canceled orders impacting business bottom lines. Meanwhile, much of the global supply chain difficulties anticipating to anticipate COVID-19 pandemic-induced lockdowns and closures, which reduced the ability of firms to satisfy global market demands.
At the pick of COVID-19 and the Los Angeles seaport congestion, many firms satisfied consumer demands by utilizing a series of innovative digital technologies which include the Internet of Things, big data to machine learning (ML). COVID-19 pandemic and the California seaport crisis demonstrate the challenges facing firms that applied 20th century supply chain models to 21st-century problems. Today, evidence suggests that companies that employed a blend of new technologies during recent crises registered efficiency and productivity by addressing customer or industry needs in real-time (Imran Ali). The concoction of new technologies gave many firms opportunities to increase productivity and efficiency through big data, intelligent software, Internet of Things (IoT), and hardware. The 4IR is setting to disrupt orthodox supply chain knowledge by offering groundbreaking ways to meet and satisfy customer needs amid crises [1].
Meanwhile, many countries and firms still lack the basic infrastructure desirable to reap the benefits of the 4IR despite the usefulness and potential for the supply industry. The succeeding sections provide a background, methodology, results and discussion introducing the concept of the Supply Web and its tenets.
History shows technological innovation has always been at the center of business productivity and social emancipation. It brought individuals and firms to mass-produce by moving from manual and small-scale trade activities to mechanization and large-scale engineering productions. Material and services that evolved from the revolutionary innovations impacted every aspect of economic activities [2]. Makers of goods and service providers from agriculture to factories practiced primitive forms of trades to address the challenges and conditions of their respective eras. Previous industrial transformation exacerbated economic activities and created processes and concepts suitable to describe and resolve enduring challenges.
Business concepts relating to earlier supply chain activities, procedures, and actions did not develop until later. The academia, industry, and governments described the activities associated with the phenomenon after they had already happened [3]. However, identifying and describing developing innovative technologies and related processes offered the supply industry concepts and procedures to structure and shape future business activities.
Figure 1 illustrates the typical model of the supply chain showing the association between firms from raw material to end-use. While the linear nature of the supply chain models was suitable to satisfy earlier business practices, it is no longer practical to address problems facing value chains in the 21st Century.
Supply chain architype.
For instance, as figure one illustrates, end-users lack the capability or option to collaborate with material (A), Transformation (B), and so forth if they were a desire to do so. The absence of these options in the linear supply chain model reduces the potential of firms to collaborate within a broader supply chain at the national or global scale.
To understand the urgency to shift supply paradigms, one must grasp the current business environment. The global population doubled since the 1980s when only a handful of companies utilized computers for business. Many companies used computer technologies for small tasks, ranging from storing essential inventory data to chart display. At the time, most firms only performed business activities without computers due to the affordability of the technology. Nevertheless, the business industry and its concepts still evolved along with the adoption of computer technology. For instance, the radio frequency identification (RFID) technology helped the retailer industry and governments describe policies and procedures associated with tracking and tracing consumer products. Hence, though RFID technology did not exist earlier, most producers and retailers could still manage data and track and trace goods through traditional bookkeeping.
Meanwhile, as consumer demand evolved, so did the supply industry by adopting technologies such as RFID in various applications, including product recalls [4]. Referring to the linear supply chain (Figure 1), RFID sensors in most retail products often connect trade and distribution, removing end-users from collaboration despite the ability of the technology to do so. However, the linear supply chain paradigm does not envisage a collaborative transaction between the consumer and the manufacturer.
As civilizations progress, the global supply industry and governments must adopt emerging technologies and concepts to address current challenges. Industry 4.0 not only gives governments and the global supply industry the necessary tools and ideas to manage challenges, but it equally provides consumers the prospect to be a part of the solution. The current supply chain models have not successfully predicted and evaded supply chain-related predicaments. The failure is arguably in how the concept of the supply chain itself.
Today, while most supply chain firms employ computer technologies, many still lack the essential technology to collaborate successfully with partners. While many firms remain indifferent in linking their pieces of machinery with others, the speed of technology advancement equally makes it difficult to address security shortfalls as they occur. Nonetheless, a partner’s lack of understanding and awareness of existing technological innovation will lead firms not to take advantage of the innovative technologies despite the rationality. In one instance, a farmer revealed during an interview to have never heard of blockchain or cloud computing [5], which many have come to consider as the cornerstone of business security and operations. Since a lack of coordination and collaboration could result in the absence of visibility and synchronized strategy between partners, firms not adopting the industry 4.0 technologies would become the gateways to substandard products and services [6]. The inability of a farmer or supply partner to successfully and securely collaborate with others at various ends of the supply spectrum could only negatively impact the resiliency of the chain.
Linear supply chain models do not provide the necessary collaboration needed to connect valued chains at various levels of the industry. The current consumer and business data necessitate supply firms connect not only with businesses but also with consumers; hence, the necessity for multidimensional collaboration. As Figure 2 shows, Industry 4.0 allows firms to exercise cooperation in terms of vertical, diagonal, and horizontal dimensions. When supply firms implement the 4IR technological tools, they enhance their ability to exchange business data internally, externally, and between partners beyond primary products (PBPP).
Three-dimensional collaboration.
The global supply industry no longer relies on the next mile or the input from the value chain to remain resilient and anticipate the next medical shortage or cargo ships bottleneck crisis. As COVID-19 pandemic and the Los Angeles cargo crises proved, the global supply industry needs better tools and concepts to anticipate an evolving global turmoil. As opposed to employing linear supply chain models, supply firms desiring competitive advantage at the international stage should implement supply web models that integrate horizontal, vertical, and diagonal dimensional business models.
This chapter intends to explain how Industry 4.0 innovative technologies impact the supply industry and introduce the tenets of the next generation of the supply chain. A qualitative exploratory design method helped to gather Industry 4.0 technologies and related concepts with impact on the supply industry to find patterns in data [7]. The mining of associated technologies and ideas was achieved utilizing codes and developing terms, which helped analyze and describe emerging themes [8]. The data used in the analysis originated from government, non-government, business, and peer-review texts.
The Supply web is the next generation of a supply chain that integrates valued chains horizontal, vertical, and diagonal dimensions through collaboration. Through Industry 4.0, supply web management (SWM) would allow firms to perform a hundred times better at fractions of the price similar firms achieved nearly fifty years ago. For instance, an iPhone device can store terabytes of data and process hundreds of business transactions in fractions of the time it would have taken a hundred 1980-era computers housed in a large building. In so far, not only the device holds a storage capacity of over a hundred earlier computers, but it is also capable of executing thousands of transactions in a record time. Modern technology has enabled businesses, individuals, and governments to conduct virtual meetings miles away, real-time monitoring of product manufacturing and delivery using automation. The current technology innovation has changed societies and demonstrates a ‘creative destruction’ currently trending to extinguish old industries [9]. Experts believe that Industry 4.0 is comparably helping developing countries as mobile phones did with personal communication. The use of trucks and drones to deliver goods in secluded and urban areas across the globe showed efficiency in developing countries [10]. Industry 4.0 enabled real-time vendor and subcontractors monitoring to manage rapid change and inventory [11] and reduce supply–demand misalignment [5]. Evidence suggests 4IR technologies or Industry 4.0 enhance visibility, interoperability, modularity, decentralization, virtualization, and service orientation [12].
Nonetheless, despite the potential of 4IR in the global supply industry, challenges remain without a deeper understanding of barriers and drivers. While a business’ lack of collaboration, awareness, and organizational inertia bare, among others, its ability to execute supply web, a firm likewise needs to master and adopt processes and tools that add value to the supply web. For instance, a firm’s plan to adopt strategies that address the reduction of supply–demand misalignment, fast-changing consumer needs, threats of legal penalties, and cost optimization could enhance its Implementation [5].
By addressing the barriers and implementing the drivers to Industry 4.0, the global supply industry would benefit of the 4IR [11]. In the interim, the adoption of Industry 4.0 necessitates investment. In contrast to small firms during the first industrial revolutions, today’s small enterprises can reap the benefits of evolving technologies at affordable costs [12]. For instance, a small firm could subcontract its operations or services to large and specialized corporations. Businesses source several activities to lower operating costs, increase market access, enhance scalability, and diminish risks [11, 13].
The Supply web is the next generation of a supply chain that integrates valued chains horizontal, vertical, and diagonal dimensions through collaboration. Through Industry 4.0, supply web management (SWM).
Which Industry 4.0 strategy supports the tenets of the next generation of the supply chain into a supply web? The answer cannot fundamentally be linear, as the strategy would be dependent on the industry. Nonetheless, firms would want strategies that can integrate basic tenets of the supply web. In so doing, firms would need to employ a blend of technologies into their business operation. While not inclusive, such technology could range from cloud computing, big data, artificial intelligence (AI), machine learning (ML), commodity sensors, robotics to automation. For the clarity and organization of concepts into the figure, the collaborative dimensions are categorized into levels: One, Two, and Three.
Figure 3 illustrates how the supply web incorporates the three-dimensional (vertical, diagonal, and horizontal) collaborations into a framework. The vertical Dimension or Level one (L1) represents internal business activities between firms that impact the main production effort. The level 1 collaborative dimension concerns firms within the same product line as A-A, B-B, and C-C.
Unit of supply web.
The main production effort is the final service product can a single, or multiple firms produce conjointly. Meanwhile, a horizontal collaborative dimension or Level Two (L2) outside the primary production when as in A-B, C-D, A-E…. For instance, a transportation firm that delivers parts or final products participates in the collaboration under this category. Finally, firms maintain a diagonal collaborative dimension or Level Three (L3) collaboration when they have business transactions that impact the main production effort’s internal and external activities. Level 3: A-A-B-B-C-C… The preponderance of Industry 4.0 elements that enable SW within and outside the main production effort would occur at this level. Firms that provide innovative technologies services from cloud computing, Big Data, ML, AI, RFID, IoT, and others add value to the supply web by enabling collaborative Dimension.
The tenets that enable tenets supply web include among others:
Throughout humankind, societies implemented innovative technologies to fix the crisis of their time. The massive backlog of cargo ships in Los Angeles ports and across the globe in October 2021 illustrates some of the issues of the state of the early supply chain models. During an interview on CNN, the Executive Director of Port of Los Angeles noted that the orchestra of players needs to get on the same schedule. COVID-19 pandemic reaffirmed that efficient inventory management continued to be a common business challenge for many firms [12]. COVID-19 induced lockdowns disrupted medical and other supply chains creating impacting commodities supply chain [6]. There is evidence that there is a need for greater collaboration between industries and governments to minimize supply disruption at the national and global scales. Firms that collaborate with multiple stakeholders have better business strategies [6].
This chapter provides a synopsis of 4IR innovative technologies and related concepts for the next generation of the supply chain. Industry 4.0 is setting the next generation of the supply chain by making it more agile and efficient than the traditional supply chain [17]. The next generation of supply chain management ought to integrate processes that share data among partners through collaborative efforts and automation enabled by the Internet of Things, machine learning to artificial intelligence.
The current global environment enables businesses to expand and connect internal processes with customers and suppliers [18]. The expansion and connections require collaboration, flexibility, redundancy, and integration impact supply chain resilience [19]. The collaboration empowers customized configuration processes and is an essential element in tracking products from suppliers to customers with customized configuration [20] I4.0 offers a set of tools to support decision making through collaboration [21].
The impact of the COVID-19 pandemic and other recent supply chain crises offered the supply industry compelling arguments for implementing4.0 [22]. The adoption of I4.0 has grown in the manufacturing and supply chain sector [23].
Several barriers and drivers exist to Industry 4.0 implementation in the supply chain, including economic, technological, social, organizational, environmental, and inter-relationships [24]. A study found the reduction in supply–demand misalignment, changing consumer needs, legal penalties, and cost optimization as drivers of I4.0. At the same time, a lack of collaboration, organizational inertia, and lack of awareness are designated as barriers [5, 25]. Despite its advantages, firms still face challenges in implementing the I4.0 and in sustaining the security requirements. The cyber community continues to register attacks on secure systems that include attacks in web applications using TLS to secure HTTP communications [17, 26].
Not enough knowledge exists on the implementation strategies of Industry 4.0 concepts for small and medium-sized enterprises [27]. Additionally, no evidence of a conceptual SCM integrates the fundamentals of Industry 4.0, henceforth suggesting the development of business models that tolerate integrative and collaborative connectivity [28].
The next generation of supply chain management needs to integrate automation of processes from manufacturing, distribution, retailing to customers through Industry 4.0. The capability gives the supply industry compelling arguments to shift from traditional supply chain models to a supply web for enhanced collaboration and efficiency. The supply web paradigm offers the supply industry to generate and transfer business data internally, externally, and between PBPP. The chapter presented and defined
I wish to thank IntechOpen for considering the chapter.
None.
"Open access contributes to scientific excellence and integrity. It opens up research results to wider analysis. It allows research results to be reused for new discoveries. And it enables the multi-disciplinary research that is needed to solve global 21st century problems. Open access connects science with society. It allows the public to engage with research. To go behind the headlines. And look at the scientific evidence. And it enables policy makers to draw on innovative solutions to societal challenges".
\n\nCarlos Moedas, the European Commissioner for Research Science and Innovation at the STM Annual Frankfurt Conference, October 2016.
",metaTitle:"About Open Access",metaDescription:"Open access contributes to scientific excellence and integrity. It opens up research results to wider analysis. It allows research results to be reused for new discoveries. And it enables the multi-disciplinary research that is needed to solve global 21st century problems. Open access connects science with society. It allows the public to engage with research. To go behind the headlines. And look at the scientific evidence. And it enables policy makers to draw on innovative solutions to societal challenges.\n\nCarlos Moedas, the European Commissioner for Research Science and Innovation at the STM Annual Frankfurt Conference, October 2016.",metaKeywords:null,canonicalURL:"about-open-access",contentRaw:'[{"type":"htmlEditorComponent","content":"The Open Access publishing movement started in the early 2000s when academic leaders from around the world participated in the formation of the Budapest Initiative. They developed recommendations for an Open Access publishing process, “which has worked for the past decade to provide the public with unrestricted, free access to scholarly research—much of which is publicly funded. Making the research publicly available to everyone—free of charge and without most copyright and licensing restrictions—will accelerate scientific research efforts and allow authors to reach a larger number of readers” (reference: http://www.budapestopenaccessinitiative.org)
\\n\\nIntechOpen’s co-founders, both scientists themselves, created the company while undertaking research in robotics at Vienna University. Their goal was to spread research freely “for scientists, by scientists’ to the rest of the world via the Open Access publishing model. The company soon became a signatory of the Budapest Initiative, which currently has more than 1000 supporting organizations worldwide, ranging from universities to funders.
\\n\\nAt IntechOpen today, we are still as committed to working with organizations and people who care about scientific discovery, to putting the academic needs of the scientific community first, and to providing an Open Access environment where scientists can maximize their contribution to scientific advancement. By opening up access to the world’s scientific research articles and book chapters, we aim to facilitate greater opportunity for collaboration, scientific discovery and progress. We subscribe wholeheartedly to the Open Access definition:
\\n\\n“By “open access” to [peer-reviewed research literature], we mean its free availability on the public internet, permitting any users to read, download, copy, distribute, print, search, or link to the full texts of these articles, crawl them for indexing, pass them as data to software, or use them for any other lawful purpose, without financial, legal, or technical barriers other than those inseparable from gaining access to the internet itself. The only constraint on reproduction and distribution, and the only role for copyright in this domain, should be to give authors control over the integrity of their work and the right to be properly acknowledged and cited” (reference: http://www.budapestopenaccessinitiative.org)
\\n\\nOAI-PMH
\\n\\nAs a firm believer in the wider dissemination of knowledge, IntechOpen supports the Open Access Initiative Protocol for Metadata Harvesting (OAI-PMH Version 2.0). Read more
\\n\\nLicense
\\n\\nBook chapters published in edited volumes are distributed under the Creative Commons Attribution 3.0 Unported License (CC BY 3.0). IntechOpen upholds a very flexible Copyright Policy. There is no copyright transfer to the publisher and Authors retain exclusive copyright to their work. All Monographs/Compacts are distributed under the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). Read more
\\n\\nPeer Review Policies
\\n\\nAll scientific works are Peer Reviewed prior to publishing. Read more
\\n\\nOA Publishing Fees
\\n\\nThe Open Access publishing model employed by IntechOpen eliminates subscription charges and pay-per-view fees, enabling readers to access research at no cost. In order to sustain operations and keep our publications freely accessible we levy an Open Access Publishing Fee for manuscripts, which helps us cover the costs of editorial work and the production of books. Read more
\\n\\nDigital Archiving Policy
\\n\\nIntechOpen is committed to ensuring the long-term preservation and the availability of all scholarly research we publish. We employ a variety of means to enable us to deliver on our commitments to the scientific community. Apart from preservation by the Croatian National Library (for publications prior to April 18, 2018) and the British Library (for publications after April 18, 2018), our entire catalogue is preserved in the CLOCKSS archive.
\\n\\nOpen Science is transparent and accessible knowledge that is shared and developed through collaborative networks.
\\n\\nOpen Science is about increased rigour, accountability, and reproducibility for research. It is based on the principles of inclusion, fairness, equity, and sharing, and ultimately seeks to change the way research is done, who is involved and how it is valued. It aims to make research more open to participation, review/refutation, improvement and (re)use for the world to benefit.
\\n\\nOpen Science refers to doing traditional science with more transparency involved at various stages, for example by openly sharing code and data. It implies a growing set of practices - within different disciplines - aiming at:
\\n\\nWe aim at improving the quality and availability of scholarly communication by promoting and practicing:
\\n\\n\\n"}]'},components:[{type:"htmlEditorComponent",content:'
The Open Access publishing movement started in the early 2000s when academic leaders from around the world participated in the formation of the Budapest Initiative. They developed recommendations for an Open Access publishing process, “which has worked for the past decade to provide the public with unrestricted, free access to scholarly research—much of which is publicly funded. Making the research publicly available to everyone—free of charge and without most copyright and licensing restrictions—will accelerate scientific research efforts and allow authors to reach a larger number of readers” (reference: http://www.budapestopenaccessinitiative.org)
\n\nIntechOpen’s co-founders, both scientists themselves, created the company while undertaking research in robotics at Vienna University. Their goal was to spread research freely “for scientists, by scientists’ to the rest of the world via the Open Access publishing model. The company soon became a signatory of the Budapest Initiative, which currently has more than 1000 supporting organizations worldwide, ranging from universities to funders.
\n\nAt IntechOpen today, we are still as committed to working with organizations and people who care about scientific discovery, to putting the academic needs of the scientific community first, and to providing an Open Access environment where scientists can maximize their contribution to scientific advancement. By opening up access to the world’s scientific research articles and book chapters, we aim to facilitate greater opportunity for collaboration, scientific discovery and progress. We subscribe wholeheartedly to the Open Access definition:
\n\n“By “open access” to [peer-reviewed research literature], we mean its free availability on the public internet, permitting any users to read, download, copy, distribute, print, search, or link to the full texts of these articles, crawl them for indexing, pass them as data to software, or use them for any other lawful purpose, without financial, legal, or technical barriers other than those inseparable from gaining access to the internet itself. The only constraint on reproduction and distribution, and the only role for copyright in this domain, should be to give authors control over the integrity of their work and the right to be properly acknowledged and cited” (reference: http://www.budapestopenaccessinitiative.org)
\n\nOAI-PMH
\n\nAs a firm believer in the wider dissemination of knowledge, IntechOpen supports the Open Access Initiative Protocol for Metadata Harvesting (OAI-PMH Version 2.0). Read more
\n\nLicense
\n\nBook chapters published in edited volumes are distributed under the Creative Commons Attribution 3.0 Unported License (CC BY 3.0). IntechOpen upholds a very flexible Copyright Policy. There is no copyright transfer to the publisher and Authors retain exclusive copyright to their work. All Monographs/Compacts are distributed under the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). Read more
\n\nPeer Review Policies
\n\nAll scientific works are Peer Reviewed prior to publishing. Read more
\n\nOA Publishing Fees
\n\nThe Open Access publishing model employed by IntechOpen eliminates subscription charges and pay-per-view fees, enabling readers to access research at no cost. In order to sustain operations and keep our publications freely accessible we levy an Open Access Publishing Fee for manuscripts, which helps us cover the costs of editorial work and the production of books. Read more
\n\nDigital Archiving Policy
\n\nIntechOpen is committed to ensuring the long-term preservation and the availability of all scholarly research we publish. We employ a variety of means to enable us to deliver on our commitments to the scientific community. Apart from preservation by the Croatian National Library (for publications prior to April 18, 2018) and the British Library (for publications after April 18, 2018), our entire catalogue is preserved in the CLOCKSS archive.
\n\nOpen Science is transparent and accessible knowledge that is shared and developed through collaborative networks.
\n\nOpen Science is about increased rigour, accountability, and reproducibility for research. It is based on the principles of inclusion, fairness, equity, and sharing, and ultimately seeks to change the way research is done, who is involved and how it is valued. It aims to make research more open to participation, review/refutation, improvement and (re)use for the world to benefit.
\n\nOpen Science refers to doing traditional science with more transparency involved at various stages, for example by openly sharing code and data. It implies a growing set of practices - within different disciplines - aiming at:
\n\nWe aim at improving the quality and availability of scholarly communication by promoting and practicing:
\n\n\n'}]},successStories:{items:[]},authorsAndEditors:{filterParams:{},profiles:[{id:"396",title:"Dr.",name:"Vedran",middleName:null,surname:"Kordic",slug:"vedran-kordic",fullName:"Vedran Kordic",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/396/images/7281_n.png",biography:"After obtaining his Master's degree in Mechanical Engineering he continued his education at the Vienna University of Technology where he obtained his PhD degree in 2004. He worked as a researcher at the Automation and Control Institute, Faculty of Electrical Engineering, Vienna University of Technology until 2008. His studies in robotics lead him not only to a PhD degree but also inspired him to co-found and build the International Journal of Advanced Robotic Systems - world's first Open Access journal in the field of robotics.",institutionString:null,institution:{name:"TU Wien",country:{name:"Austria"}}},{id:"441",title:"Ph.D.",name:"Jaekyu",middleName:null,surname:"Park",slug:"jaekyu-park",fullName:"Jaekyu Park",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/441/images/1881_n.jpg",biography:null,institutionString:null,institution:{name:"LG Corporation (South Korea)",country:{name:"Korea, South"}}},{id:"465",title:"Dr",name:"Christian",middleName:null,surname:"Martens",slug:"christian-martens",fullName:"Christian Martens",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"479",title:"Dr.",name:"Valentina",middleName:null,surname:"Colla",slug:"valentina-colla",fullName:"Valentina Colla",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/479/images/358_n.jpg",biography:null,institutionString:null,institution:{name:"Sant'Anna School of Advanced Studies",country:{name:"Italy"}}},{id:"494",title:"PhD",name:"Loris",middleName:null,surname:"Nanni",slug:"loris-nanni",fullName:"Loris Nanni",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/494/images/system/494.jpg",biography:"Loris Nanni received his Master Degree cum laude on June-2002 from the University of Bologna, and the April 26th 2006 he received his Ph.D. in Computer Engineering at DEIS, University of Bologna. On September, 29th 2006 he has won a post PhD fellowship from the university of Bologna (from October 2006 to October 2008), at the competitive examination he was ranked first in the industrial engineering area. He extensively served as referee for several international journals. He is author/coauthor of more than 100 research papers. He has been involved in some projects supported by MURST and European Community. His research interests include pattern recognition, bioinformatics, and biometric systems (fingerprint classification and recognition, signature verification, face recognition).",institutionString:null,institution:null},{id:"496",title:"Dr.",name:"Carlos",middleName:null,surname:"Leon",slug:"carlos-leon",fullName:"Carlos Leon",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Seville",country:{name:"Spain"}}},{id:"512",title:"Dr.",name:"Dayang",middleName:null,surname:"Jawawi",slug:"dayang-jawawi",fullName:"Dayang Jawawi",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Technology Malaysia",country:{name:"Malaysia"}}},{id:"528",title:"Dr.",name:"Kresimir",middleName:null,surname:"Delac",slug:"kresimir-delac",fullName:"Kresimir Delac",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/528/images/system/528.jpg",biography:"K. Delac received his B.Sc.E.E. degree in 2003 and is currentlypursuing a Ph.D. degree at the University of Zagreb, Faculty of Electrical Engineering andComputing. His current research interests are digital image analysis, pattern recognition andbiometrics.",institutionString:null,institution:{name:"University of Zagreb",country:{name:"Croatia"}}},{id:"557",title:"Dr.",name:"Andon",middleName:"Venelinov",surname:"Topalov",slug:"andon-topalov",fullName:"Andon Topalov",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/557/images/1927_n.jpg",biography:"Dr. Andon V. Topalov received the MSc degree in Control Engineering from the Faculty of Information Systems, Technologies, and Automation at Moscow State University of Civil Engineering (MGGU) in 1979. He then received his PhD degree in Control Engineering from the Department of Automation and Remote Control at Moscow State Mining University (MGSU), Moscow, in 1984. From 1985 to 1986, he was a Research Fellow in the Research Institute for Electronic Equipment, ZZU AD, Plovdiv, Bulgaria. In 1986, he joined the Department of Control Systems, Technical University of Sofia at the Plovdiv campus, where he is presently a Full Professor. He has held long-term visiting Professor/Scholar positions at various institutions in South Korea, Turkey, Mexico, Greece, Belgium, UK, and Germany. And he has coauthored one book and authored or coauthored more than 80 research papers in conference proceedings and journals. His current research interests are in the fields of intelligent control and robotics.",institutionString:null,institution:{name:"Technical University of Sofia",country:{name:"Bulgaria"}}},{id:"585",title:"Prof.",name:"Munir",middleName:null,surname:"Merdan",slug:"munir-merdan",fullName:"Munir Merdan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/585/images/system/585.jpg",biography:"Munir Merdan received the M.Sc. degree in mechanical engineering from the Technical University of Sarajevo, Bosnia and Herzegovina, in 2001, and the Ph.D. degree in electrical engineering from the Vienna University of Technology, Vienna, Austria, in 2009.Since 2005, he has been at the Automation and Control Institute, Vienna University of Technology, where he is currently a Senior Researcher. His research interests include the application of agent technology for achieving agile control in the manufacturing environment.",institutionString:null,institution:null},{id:"605",title:"Prof",name:"Dil",middleName:null,surname:"Hussain",slug:"dil-hussain",fullName:"Dil Hussain",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/605/images/system/605.jpg",biography:"Dr. Dil Muhammad Akbar Hussain is a professor of Electronics Engineering & Computer Science at the Department of Energy Technology, Aalborg University Denmark. Professor Akbar has a Master degree in Digital Electronics from Govt. College University, Lahore Pakistan and a P-hD degree in Control Engineering from the School of Engineering and Applied Sciences, University of Sussex United Kingdom. Aalborg University has Two Satellite Campuses, one in Copenhagen (Aalborg University Copenhagen) and the other in Esbjerg (Aalborg University Esbjerg).\n· He is a member of prestigious IEEE (Institute of Electrical and Electronics Engineers), and IAENG (International Association of Engineers) organizations. \n· He is the chief Editor of the Journal of Software Engineering.\n· He is the member of the Editorial Board of International Journal of Computer Science and Software Technology (IJCSST) and International Journal of Computer Engineering and Information Technology. \n· He is also the Editor of Communication in Computer and Information Science CCIS-20 by Springer.\n· Reviewer For Many Conferences\nHe is the lead person in making collaboration agreements between Aalborg University and many universities of Pakistan, for which the MOU’s (Memorandum of Understanding) have been signed.\nProfessor Akbar is working in Academia since 1990, he started his career as a Lab demonstrator/TA at the University of Sussex. After finishing his P. hD degree in 1992, he served in the Industry as a Scientific Officer and continued his academic career as a visiting scholar for a number of educational institutions. In 1996 he joined National University of Science & Technology Pakistan (NUST) as an Associate Professor; NUST is one of the top few universities in Pakistan. In 1999 he joined an International Company Lineo Inc, Canada as Manager Compiler Group, where he headed the group for developing Compiler Tool Chain and Porting of Operating Systems for the BLACKfin processor. The processor development was a joint venture by Intel and Analog Devices. In 2002 Lineo Inc., was taken over by another company, so he joined Aalborg University Denmark as an Assistant Professor.\nProfessor Akbar has truly a multi-disciplined career and he continued his legacy and making progress in many areas of his interests both in teaching and research. He has contributed in stochastic estimation of control area especially, in the Multiple Target Tracking and Interactive Multiple Model (IMM) research, Ball & Beam Control Problem, Robotics, Levitation Control. He has contributed in developing Algorithms for Fingerprint Matching, Computer Vision and Face Recognition. He has been supervising Pattern Recognition, Formal Languages and Distributed Processing projects for several years. He has reviewed many books on Management, Computer Science. Currently, he is an active and permanent reviewer for many international conferences and symposia and the program committee member for many international conferences.\nIn teaching he has taught the core computer science subjects like, Digital Design, Real Time Embedded System Programming, Operating Systems, Software Engineering, Data Structures, Databases, Compiler Construction. In the Engineering side, Digital Signal Processing, Computer Architecture, Electronics Devices, Digital Filtering and Engineering Management.\nApart from his Academic Interest and activities he loves sport especially, Cricket, Football, Snooker and Squash. He plays cricket for Esbjerg city in the second division team as an opener wicket keeper batsman. He is a very good player of squash but has not played squash since his arrival in Denmark.",institutionString:null,institution:null},{id:"611",title:"Prof.",name:"T",middleName:null,surname:"Nagarajan",slug:"t-nagarajan",fullName:"T Nagarajan",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Universiti Teknologi Petronas",country:{name:"Malaysia"}}}],filtersByRegion:[{group:"region",caption:"North America",value:1,count:6581},{group:"region",caption:"Middle and South America",value:2,count:5888},{group:"region",caption:"Africa",value:3,count:2381},{group:"region",caption:"Asia",value:4,count:12507},{group:"region",caption:"Australia and Oceania",value:5,count:1006},{group:"region",caption:"Europe",value:6,count:17528}],offset:12,limit:12,total:132501},chapterEmbeded:{data:{}},editorApplication:{success:null,errors:{}},ofsBooks:{filterParams:{hasNoEditors:"0",sort:"-dateEndThirdStepPublish",src:"N-F-0-T1"},books:[{type:"book",id:"9985",title:"Geostatistics",subtitle:null,isOpenForSubmission:!0,hash:"423cb3896195a618c4acb493ce4fd23d",slug:null,bookSignature:"Prof. Jeffrey M. Yarus, Dr. Marko Maucec, Dr. Timothy C. Coburn and Associate Prof. Michael Pyrcz",coverURL:"https://cdn.intechopen.com/books/images_new/9985.jpg",editedByType:null,editors:[{id:"78011",title:"Prof.",name:"Jeffrey M.",surname:"Yarus",slug:"jeffrey-m.-yarus",fullName:"Jeffrey M. Yarus"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11905",title:"Rare Earth Elements - Emerging Advances, Technology Utilization, and Resource Procurement",subtitle:null,isOpenForSubmission:!0,hash:"38ffcf92affa26770585dbc04b3742fe",slug:null,bookSignature:"Dr. Michael Thomas Aide",coverURL:"https://cdn.intechopen.com/books/images_new/11905.jpg",editedByType:null,editors:[{id:"185895",title:"Dr.",name:"Michael",surname:"Aide",slug:"michael-aide",fullName:"Michael Aide"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11848",title:"Immunosuppression and Immunomodulation",subtitle:null,isOpenForSubmission:!0,hash:"ed8e45c9b1a36b2e913208c4d37dbc7f",slug:null,bookSignature:"Dr. Rajeev K. Tyagi, Dr. Prakriti Sharma and Dr. Praveen Sharma",coverURL:"https://cdn.intechopen.com/books/images_new/11848.jpg",editedByType:null,editors:[{id:"201069",title:"Dr.",name:"Rajeev",surname:"Tyagi",slug:"rajeev-tyagi",fullName:"Rajeev Tyagi"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11447",title:"Swarm Intelligence - Recent Advances and Current Applications",subtitle:null,isOpenForSubmission:!0,hash:"f68e3c3430a74fc7a7eb97f6ea2bb42e",slug:null,bookSignature:"Dr. Marco Antonio Aceves Fernandez",coverURL:"https://cdn.intechopen.com/books/images_new/11447.jpg",editedByType:null,editors:[{id:"24555",title:"Dr.",name:"Marco Antonio",surname:"Aceves Fernandez",slug:"marco-antonio-aceves-fernandez",fullName:"Marco Antonio Aceves Fernandez"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11815",title:"Pediatric Oral Health - New Insights",subtitle:null,isOpenForSubmission:!0,hash:"e55e88cf5885a68cdf470925b35cbbd8",slug:null,bookSignature:"Prof. Mandeep Singh Virdi",coverURL:"https://cdn.intechopen.com/books/images_new/11815.jpg",editedByType:null,editors:[{id:"89556",title:"Prof.",name:"Mandeep",surname:"Virdi",slug:"mandeep-virdi",fullName:"Mandeep Virdi"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11872",title:"Peripheral Arterial Disease - The Challenges of Revascularization",subtitle:null,isOpenForSubmission:!0,hash:"80be3d16e4c8f89f3501ed408729f695",slug:null,bookSignature:"Prof. Ana Terezinha Guillaumon, Dr. Daniel Emilio Dalledone Siqueira and Dr. Martin Geiger",coverURL:"https://cdn.intechopen.com/books/images_new/11872.jpg",editedByType:null,editors:[{id:"251226",title:"Prof.",name:"Ana Terezinha",surname:"Guillaumon",slug:"ana-terezinha-guillaumon",fullName:"Ana Terezinha Guillaumon"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11533",title:"Advances in Green Electronics Technologies",subtitle:null,isOpenForSubmission:!0,hash:"209fb1d781e97e58e1b2098b8976e2c3",slug:null,bookSignature:"Dr. Albert Sabban",coverURL:"https://cdn.intechopen.com/books/images_new/11533.jpg",editedByType:null,editors:[{id:"16889",title:"Dr.",name:"Albert",surname:"Sabban",slug:"albert-sabban",fullName:"Albert Sabban"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11433",title:"Human Migration in the Last Three Centuries",subtitle:null,isOpenForSubmission:!0,hash:"9836df9e82aa9f82e3852a60204909a8",slug:null,bookSignature:"Dr. Ingrid Muenstermann",coverURL:"https://cdn.intechopen.com/books/images_new/11433.jpg",editedByType:null,editors:[{id:"77112",title:"Dr.",name:"Ingrid",surname:"Muenstermann",slug:"ingrid-muenstermann",fullName:"Ingrid Muenstermann"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11630",title:"Life in Extreme Environments - Diversity, Adaptability and Valuable Resources of Bioactive Molecules",subtitle:null,isOpenForSubmission:!0,hash:"9c39aa5fd22296ba53d87df6d761a5fc",slug:null,bookSignature:"Dr. Afef Najjari",coverURL:"https://cdn.intechopen.com/books/images_new/11630.jpg",editedByType:null,editors:[{id:"196823",title:"Dr.",name:"Afef",surname:"Najjari",slug:"afef-najjari",fullName:"Afef Najjari"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11842",title:"Altimetry - Theory, Applications and Recent Advances",subtitle:null,isOpenForSubmission:!0,hash:"b2b6e7b58333453ef7b73416d8fdfaf3",slug:null,bookSignature:"Prof. Tomislav Bašić",coverURL:"https://cdn.intechopen.com/books/images_new/11842.jpg",editedByType:null,editors:[{id:"343125",title:"Prof.",name:"Tomislav",surname:"Bašić",slug:"tomislav-basic",fullName:"Tomislav Bašić"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11804",title:"CRISPR Technology",subtitle:null,isOpenForSubmission:!0,hash:"4051570f538bd3315e051267180abe37",slug:null,bookSignature:"Dr. Yuan-Chuan Chen",coverURL:"https://cdn.intechopen.com/books/images_new/11804.jpg",editedByType:null,editors:[{id:"185559",title:"Dr.",name:"Yuan-Chuan",surname:"Chen",slug:"yuan-chuan-chen",fullName:"Yuan-Chuan Chen"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"12104",title:"Viral Outbreaks - Global Trends and Perspectives",subtitle:null,isOpenForSubmission:!0,hash:"60828f26feed5832a47a13caac706c08",slug:null,bookSignature:"Prof. Shailendra K. Saxena",coverURL:"https://cdn.intechopen.com/books/images_new/12104.jpg",editedByType:null,editors:[{id:"158026",title:"Prof.",name:"Shailendra K.",surname:"Saxena",slug:"shailendra-k.-saxena",fullName:"Shailendra K. Saxena"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],filtersByTopic:[{group:"topic",caption:"Agricultural and Biological Sciences",value:5,count:41},{group:"topic",caption:"Biochemistry, Genetics and Molecular Biology",value:6,count:11},{group:"topic",caption:"Business, Management and Economics",value:7,count:6},{group:"topic",caption:"Chemistry",value:8,count:21},{group:"topic",caption:"Computer and Information Science",value:9,count:21},{group:"topic",caption:"Earth and Planetary Sciences",value:10,count:15},{group:"topic",caption:"Engineering",value:11,count:59},{group:"topic",caption:"Environmental Sciences",value:12,count:8},{group:"topic",caption:"Immunology and Microbiology",value:13,count:10},{group:"topic",caption:"Materials Science",value:14,count:27},{group:"topic",caption:"Mathematics",value:15,count:9},{group:"topic",caption:"Medicine",value:16,count:124},{group:"topic",caption:"Nanotechnology and Nanomaterials",value:17,count:9},{group:"topic",caption:"Neuroscience",value:18,count:3},{group:"topic",caption:"Pharmacology, Toxicology and Pharmaceutical Science",value:19,count:6},{group:"topic",caption:"Physics",value:20,count:11},{group:"topic",caption:"Psychology",value:21,count:10},{group:"topic",caption:"Robotics",value:22,count:4},{group:"topic",caption:"Social Sciences",value:23,count:9},{group:"topic",caption:"Veterinary Medicine and Science",value:25,count:4}],offset:12,limit:12,total:410},popularBooks:{featuredBooks:[{type:"book",id:"10584",title:"Engineered Wood Products for Construction",subtitle:null,isOpenForSubmission:!1,hash:"421757c56a3735986055250821275a51",slug:"engineered-wood-products-for-construction",bookSignature:"Meng Gong",coverURL:"https://cdn.intechopen.com/books/images_new/10584.jpg",editors:[{id:"274242",title:"Dr.",name:"Meng",middleName:null,surname:"Gong",slug:"meng-gong",fullName:"Meng Gong"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10222",title:"Demyelination Disorders",subtitle:null,isOpenForSubmission:!1,hash:"b6c26ceccacdde70c41c587361bd5558",slug:"demyelination-disorders",bookSignature:"Stavros J. Baloyannis, Fabian H. Rossi and Welwin Liu",coverURL:"https://cdn.intechopen.com/books/images_new/10222.jpg",editors:[{id:"156098",title:"Emeritus Prof.",name:"Stavros J.",middleName:"J.",surname:"Baloyannis",slug:"stavros-j.-baloyannis",fullName:"Stavros J. Baloyannis"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9544",title:"Global Trade in the Emerging Business Environment",subtitle:null,isOpenForSubmission:!1,hash:"fb8cb09b9599246add78d508a98273d5",slug:"global-trade-in-the-emerging-business-environment",bookSignature:"Muhammad Mohiuddin, Jingbin Wang , Md. Samim Al Azad and Selim Ahmed",coverURL:"https://cdn.intechopen.com/books/images_new/9544.jpg",editors:[{id:"418514",title:"Dr.",name:"Muhammad",middleName:null,surname:"Mohiuddin",slug:"muhammad-mohiuddin",fullName:"Muhammad Mohiuddin"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10979",title:"Parenting",subtitle:"Challenges of Child Rearing in a Changing Society",isOpenForSubmission:!1,hash:"6f345ebcf4fd61e73643c69063a12c7b",slug:"parenting-challenges-of-child-rearing-in-a-changing-society",bookSignature:"Sayyed Ali Samadi",coverURL:"https://cdn.intechopen.com/books/images_new/10979.jpg",editors:[{id:"52145",title:"Dr.",name:"Sayyed Ali",middleName:null,surname:"Samadi",slug:"sayyed-ali-samadi",fullName:"Sayyed Ali Samadi"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9808",title:"Contemporary Topics in Patient Safety",subtitle:"Volume 1",isOpenForSubmission:!1,hash:"fb6371607c2c6c02c6a2af8892765aba",slug:"contemporary-topics-in-patient-safety-volume-1",bookSignature:"Stanislaw P. Stawicki and Michael S. Firstenberg",coverURL:"https://cdn.intechopen.com/books/images_new/9808.jpg",editors:[{id:"181694",title:"Dr.",name:"Stanislaw P.",middleName:null,surname:"Stawicki",slug:"stanislaw-p.-stawicki",fullName:"Stanislaw P. Stawicki"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10681",title:"Biodegradation Technology of Organic and Inorganic Pollutants",subtitle:null,isOpenForSubmission:!1,hash:"9a6e10e02788092872fd249436898e97",slug:"biodegradation-technology-of-organic-and-inorganic-pollutants",bookSignature:"Kassio Ferreira Mendes, Rodrigo Nogueira de Sousa and Kamila Cabral Mielke",coverURL:"https://cdn.intechopen.com/books/images_new/10681.jpg",editors:[{id:"197720",title:"Ph.D.",name:"Kassio",middleName:null,surname:"Ferreira Mendes",slug:"kassio-ferreira-mendes",fullName:"Kassio Ferreira Mendes"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10764",title:"Antenna Systems",subtitle:null,isOpenForSubmission:!1,hash:"2fbf1c7a5d92723f08198fc9b526a8ad",slug:"antenna-systems",bookSignature:"Hussain Al-Rizzo and Said Abushamleh",coverURL:"https://cdn.intechopen.com/books/images_new/10764.jpg",editors:[{id:"153384",title:"Prof.",name:"Hussain",middleName:null,surname:"Al-Rizzo",slug:"hussain-al-rizzo",fullName:"Hussain Al-Rizzo"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10668",title:"Sustainability of Concrete With Synthetic and Recycled Aggregates",subtitle:null,isOpenForSubmission:!1,hash:"55856c6a8bc3a5b21dae5a1af09a56b6",slug:"sustainability-of-concrete-with-synthetic-and-recycled-aggregates",bookSignature:"Hosam M. Saleh",coverURL:"https://cdn.intechopen.com/books/images_new/10668.jpg",editors:[{id:"144691",title:"Prof.",name:"Hosam",middleName:null,surname:"Saleh",slug:"hosam-saleh",fullName:"Hosam Saleh"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10803",title:"Reactive Oxygen Species",subtitle:null,isOpenForSubmission:!1,hash:"176adcf090fdd1f93cb8ce3146e79ca1",slug:"reactive-oxygen-species",bookSignature:"Rizwan Ahmad",coverURL:"https://cdn.intechopen.com/books/images_new/10803.jpg",editors:[{id:"40482",title:null,name:"Rizwan",middleName:null,surname:"Ahmad",slug:"rizwan-ahmad",fullName:"Rizwan Ahmad"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9032",title:"Corporate Social Responsibility",subtitle:null,isOpenForSubmission:!1,hash:"f609bf3251d7cc7bae0099a4374adfc3",slug:"corporate-social-responsibility",bookSignature:"Beatrice Orlando",coverURL:"https://cdn.intechopen.com/books/images_new/9032.jpg",editors:[{id:"232969",title:"Prof.",name:"Beatrice",middleName:null,surname:"Orlando",slug:"beatrice-orlando",fullName:"Beatrice Orlando"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10351",title:"Enhanced Liposuction",subtitle:"New Perspectives and Techniques",isOpenForSubmission:!1,hash:"f08ed6de16da357614586c5b58ed4dfa",slug:"enhanced-liposuction-new-perspectives-and-techniques",bookSignature:"Diane Irvine Duncan",coverURL:"https://cdn.intechopen.com/books/images_new/10351.jpg",editors:[{id:"279869",title:"Dr.",name:"Diane Irvine",middleName:null,surname:"Duncan",slug:"diane-irvine-duncan",fullName:"Diane Irvine Duncan"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10779",title:"21st Century Nanostructured Materials",subtitle:"Physics, Chemistry, Classification, and Emerging Applications in Industry, Biomedicine, and Agriculture",isOpenForSubmission:!1,hash:"72c67f97f9bef68200df115b5fd79884",slug:"21st-century-nanostructured-materials-physics-chemistry-classification-and-emerging-applications-in-industry-biomedicine-and-agriculture",bookSignature:"Phuong V. Pham",coverURL:"https://cdn.intechopen.com/books/images_new/10779.jpg",editors:[{id:"236073",title:"Dr.",name:"Phuong",middleName:"Viet",surname:"Pham",slug:"phuong-pham",fullName:"Phuong Pham"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}}],offset:12,limit:12,total:4386},hotBookTopics:{hotBooks:[],offset:0,limit:12,total:null},publish:{},publishingProposal:{success:null,errors:{}},books:{featuredBooks:[{type:"book",id:"10584",title:"Engineered Wood Products for Construction",subtitle:null,isOpenForSubmission:!1,hash:"421757c56a3735986055250821275a51",slug:"engineered-wood-products-for-construction",bookSignature:"Meng Gong",coverURL:"https://cdn.intechopen.com/books/images_new/10584.jpg",publishedDate:"April 28th 2022",numberOfDownloads:3665,editors:[{id:"274242",title:"Dr.",name:"Meng",middleName:null,surname:"Gong",slug:"meng-gong",fullName:"Meng Gong"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10222",title:"Demyelination Disorders",subtitle:null,isOpenForSubmission:!1,hash:"b6c26ceccacdde70c41c587361bd5558",slug:"demyelination-disorders",bookSignature:"Stavros J. Baloyannis, Fabian H. Rossi and Welwin Liu",coverURL:"https://cdn.intechopen.com/books/images_new/10222.jpg",publishedDate:"May 4th 2022",numberOfDownloads:1713,editors:[{id:"156098",title:"Emeritus Prof.",name:"Stavros J.",middleName:"J.",surname:"Baloyannis",slug:"stavros-j.-baloyannis",fullName:"Stavros J. Baloyannis"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9544",title:"Global Trade in the Emerging Business Environment",subtitle:null,isOpenForSubmission:!1,hash:"fb8cb09b9599246add78d508a98273d5",slug:"global-trade-in-the-emerging-business-environment",bookSignature:"Muhammad Mohiuddin, Jingbin Wang , Md. Samim Al Azad and Selim Ahmed",coverURL:"https://cdn.intechopen.com/books/images_new/9544.jpg",publishedDate:"April 28th 2022",numberOfDownloads:2481,editors:[{id:"418514",title:"Dr.",name:"Muhammad",middleName:null,surname:"Mohiuddin",slug:"muhammad-mohiuddin",fullName:"Muhammad Mohiuddin"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10979",title:"Parenting",subtitle:"Challenges of Child Rearing in a Changing Society",isOpenForSubmission:!1,hash:"6f345ebcf4fd61e73643c69063a12c7b",slug:"parenting-challenges-of-child-rearing-in-a-changing-society",bookSignature:"Sayyed Ali Samadi",coverURL:"https://cdn.intechopen.com/books/images_new/10979.jpg",publishedDate:"May 4th 2022",numberOfDownloads:1107,editors:[{id:"52145",title:"Dr.",name:"Sayyed Ali",middleName:null,surname:"Samadi",slug:"sayyed-ali-samadi",fullName:"Sayyed Ali Samadi"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9808",title:"Contemporary Topics in Patient Safety",subtitle:"Volume 1",isOpenForSubmission:!1,hash:"fb6371607c2c6c02c6a2af8892765aba",slug:"contemporary-topics-in-patient-safety-volume-1",bookSignature:"Stanislaw P. Stawicki and Michael S. Firstenberg",coverURL:"https://cdn.intechopen.com/books/images_new/9808.jpg",publishedDate:"April 20th 2022",numberOfDownloads:3307,editors:[{id:"181694",title:"Dr.",name:"Stanislaw P.",middleName:null,surname:"Stawicki",slug:"stanislaw-p.-stawicki",fullName:"Stanislaw P. Stawicki"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10681",title:"Biodegradation Technology of Organic and Inorganic Pollutants",subtitle:null,isOpenForSubmission:!1,hash:"9a6e10e02788092872fd249436898e97",slug:"biodegradation-technology-of-organic-and-inorganic-pollutants",bookSignature:"Kassio Ferreira Mendes, Rodrigo Nogueira de Sousa and Kamila Cabral Mielke",coverURL:"https://cdn.intechopen.com/books/images_new/10681.jpg",publishedDate:"April 20th 2022",numberOfDownloads:3266,editors:[{id:"197720",title:"Ph.D.",name:"Kassio",middleName:null,surname:"Ferreira Mendes",slug:"kassio-ferreira-mendes",fullName:"Kassio Ferreira Mendes"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10764",title:"Antenna Systems",subtitle:null,isOpenForSubmission:!1,hash:"2fbf1c7a5d92723f08198fc9b526a8ad",slug:"antenna-systems",bookSignature:"Hussain Al-Rizzo and Said Abushamleh",coverURL:"https://cdn.intechopen.com/books/images_new/10764.jpg",publishedDate:"April 28th 2022",numberOfDownloads:1868,editors:[{id:"153384",title:"Prof.",name:"Hussain",middleName:null,surname:"Al-Rizzo",slug:"hussain-al-rizzo",fullName:"Hussain Al-Rizzo"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10668",title:"Sustainability of Concrete With Synthetic and Recycled Aggregates",subtitle:null,isOpenForSubmission:!1,hash:"55856c6a8bc3a5b21dae5a1af09a56b6",slug:"sustainability-of-concrete-with-synthetic-and-recycled-aggregates",bookSignature:"Hosam M. Saleh",coverURL:"https://cdn.intechopen.com/books/images_new/10668.jpg",publishedDate:"May 4th 2022",numberOfDownloads:856,editors:[{id:"144691",title:"Prof.",name:"Hosam",middleName:null,surname:"Saleh",slug:"hosam-saleh",fullName:"Hosam Saleh"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10803",title:"Reactive Oxygen Species",subtitle:null,isOpenForSubmission:!1,hash:"176adcf090fdd1f93cb8ce3146e79ca1",slug:"reactive-oxygen-species",bookSignature:"Rizwan Ahmad",coverURL:"https://cdn.intechopen.com/books/images_new/10803.jpg",publishedDate:"April 28th 2022",numberOfDownloads:1704,editors:[{id:"40482",title:null,name:"Rizwan",middleName:null,surname:"Ahmad",slug:"rizwan-ahmad",fullName:"Rizwan Ahmad"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9032",title:"Corporate Social Responsibility",subtitle:null,isOpenForSubmission:!1,hash:"f609bf3251d7cc7bae0099a4374adfc3",slug:"corporate-social-responsibility",bookSignature:"Beatrice Orlando",coverURL:"https://cdn.intechopen.com/books/images_new/9032.jpg",publishedDate:"March 16th 2022",numberOfDownloads:7489,editors:[{id:"232969",title:"Prof.",name:"Beatrice",middleName:null,surname:"Orlando",slug:"beatrice-orlando",fullName:"Beatrice Orlando"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}}],latestBooks:[{type:"book",id:"8737",title:"Rabies Virus at the Beginning of 21st Century",subtitle:null,isOpenForSubmission:!1,hash:"49cce3f548da548c718c865feb343509",slug:"rabies-virus-at-the-beginning-of-21st-century",bookSignature:"Sergey Tkachev",coverURL:"https://cdn.intechopen.com/books/images_new/8737.jpg",editedByType:"Edited by",publishedDate:"May 11th 2022",editors:[{id:"61139",title:"Dr.",name:"Sergey",middleName:null,surname:"Tkachev",slug:"sergey-tkachev",fullName:"Sergey Tkachev"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10861",title:"Furan Derivatives",subtitle:"Recent Advances and Applications",isOpenForSubmission:!1,hash:"fdfc39cecd82f91b0effac994f75c877",slug:"furan-derivatives-recent-advances-and-applications",bookSignature:"Anish Khan, Mohammed Muzibur Rahman, M. Ramesh, Salman Ahmad Khan and Abdullah Mohammed Ahmed Asiri",coverURL:"https://cdn.intechopen.com/books/images_new/10861.jpg",editedByType:"Edited by",publishedDate:"May 11th 2022",editors:[{id:"293058",title:"Dr.",name:"Anish",middleName:null,surname:"Khan",slug:"anish-khan",fullName:"Anish Khan"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10356",title:"Natural Medicinal Plants",subtitle:null,isOpenForSubmission:!1,hash:"943e56ccaaf19ff696d25aa638ae37d6",slug:"natural-medicinal-plants",bookSignature:"Hany A. El-Shemy",coverURL:"https://cdn.intechopen.com/books/images_new/10356.jpg",editedByType:"Edited by",publishedDate:"May 11th 2022",editors:[{id:"54719",title:"Prof.",name:"Hany",middleName:null,surname:"El-Shemy",slug:"hany-el-shemy",fullName:"Hany El-Shemy"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10870",title:"Ultrasound Imaging",subtitle:"Current Topics",isOpenForSubmission:!1,hash:"2f0bc3733ab226d67fa73759ef0e12ad",slug:"ultrasound-imaging-current-topics",bookSignature:"Felix Okechukwu Erondu",coverURL:"https://cdn.intechopen.com/books/images_new/10870.jpg",editedByType:"Edited by",publishedDate:"May 11th 2022",editors:[{id:"68312",title:"Prof.",name:"Felix",middleName:null,surname:"Okechukwu Erondu",slug:"felix-okechukwu-erondu",fullName:"Felix Okechukwu Erondu"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11392",title:"Leadership in a Changing World",subtitle:"A Multidimensional Perspective",isOpenForSubmission:!1,hash:"86a6d33cf601587e591064ce92effc02",slug:"leadership-in-a-changing-world-a-multidimensional-perspective",bookSignature:"Muhammad Mohiuddin, Bilal Khalid, Md. Samim Al Azad and Slimane Ed-dafali",coverURL:"https://cdn.intechopen.com/books/images_new/11392.jpg",editedByType:"Edited by",publishedDate:"May 11th 2022",editors:[{id:"418514",title:"Dr.",name:"Muhammad",middleName:null,surname:"Mohiuddin",slug:"muhammad-mohiuddin",fullName:"Muhammad Mohiuddin"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10400",title:"The Application of Ant Colony Optimization",subtitle:null,isOpenForSubmission:!1,hash:"f4fdfd07ee1ab99fb7c740d6d0c144c6",slug:"the-application-of-ant-colony-optimization",bookSignature:"Ali Soofastaei",coverURL:"https://cdn.intechopen.com/books/images_new/10400.jpg",editedByType:"Edited by",publishedDate:"May 11th 2022",editors:[{id:"257455",title:"Dr.",name:"Ali",middleName:null,surname:"Soofastaei",slug:"ali-soofastaei",fullName:"Ali Soofastaei"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10915",title:"Leadership",subtitle:"New Insights",isOpenForSubmission:!1,hash:"0d72e79892f2a020cee66a52d09de5a4",slug:"leadership-new-insights",bookSignature:"Mário Franco",coverURL:"https://cdn.intechopen.com/books/images_new/10915.jpg",editedByType:"Edited by",publishedDate:"May 11th 2022",editors:[{id:"105529",title:"Dr.",name:"Mário",middleName:null,surname:"Franco",slug:"mario-franco",fullName:"Mário Franco"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10683",title:"Technological Innovations and Advances in Hydropower Engineering",subtitle:null,isOpenForSubmission:!1,hash:"7ce7ad8768bd2cad155470fe1fd883f4",slug:"technological-innovations-and-advances-in-hydropower-engineering",bookSignature:"Yizi Shang, Ling Shang and Xiaofei Li",coverURL:"https://cdn.intechopen.com/books/images_new/10683.jpg",editedByType:"Edited by",publishedDate:"May 11th 2022",editors:[{id:"349630",title:"Dr.",name:"Yizi",middleName:null,surname:"Shang",slug:"yizi-shang",fullName:"Yizi Shang"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"7102",title:"Pneumonia",subtitle:null,isOpenForSubmission:!1,hash:"9fd70142814192dcec58a176749f1b60",slug:"pneumonia",bookSignature:"Nima Rezaei",coverURL:"https://cdn.intechopen.com/books/images_new/7102.jpg",editedByType:"Edited by",publishedDate:"May 11th 2022",editors:[{id:"116250",title:"Dr.",name:"Nima",middleName:null,surname:"Rezaei",slug:"nima-rezaei",fullName:"Nima Rezaei"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9670",title:"Current Trends in Wheat Research",subtitle:null,isOpenForSubmission:!1,hash:"89d795987f1747a76eee532700d2093d",slug:"current-trends-in-wheat-research",bookSignature:"Mahmood-ur-Rahman Ansari",coverURL:"https://cdn.intechopen.com/books/images_new/9670.jpg",editedByType:"Edited by",publishedDate:"May 11th 2022",editors:[{id:"185476",title:"Dr.",name:"Mahmood-ur-Rahman",middleName:null,surname:"Ansari",slug:"mahmood-ur-rahman-ansari",fullName:"Mahmood-ur-Rahman Ansari"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}]},subject:{topic:{id:"233",title:"Cognitive Science",slug:"cognitive-science",parent:{id:"21",title:"Psychology",slug:"psychology"},numberOfBooks:6,numberOfSeries:0,numberOfAuthorsAndEditors:144,numberOfWosCitations:28,numberOfCrossrefCitations:33,numberOfDimensionsCitations:47,videoUrl:null,fallbackUrl:null,description:null},booksByTopicFilter:{topicId:"233",sort:"-publishedDate",limit:12,offset:0},booksByTopicCollection:[{type:"book",id:"10978",title:"Mind and Matter",subtitle:"Challenges and Opportunities in Cognitive Semiotics and Aesthetics",isOpenForSubmission:!1,hash:"938b8668018c9338fbc8992e8e03f971",slug:"mind-and-matter-challenges-and-opportunities-in-cognitive-semiotics-and-aesthetics",bookSignature:"Asun López-Varela Azcárate",coverURL:"https://cdn.intechopen.com/books/images_new/10978.jpg",editedByType:"Edited by",editors:[{id:"302731",title:null,name:"Asun",middleName:null,surname:"López-Varela Azcárate",slug:"asun-lopez-varela-azcarate",fullName:"Asun López-Varela Azcárate"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10910",title:"Learning Disabilities",subtitle:"Neurobiology, Assessment, Clinical Features and Treatments",isOpenForSubmission:!1,hash:"0999e5f759c2380ae5a4a2ee0835c98d",slug:"learning-disabilities-neurobiology-assessment-clinical-features-and-treatments",bookSignature:"Sandro Misciagna",coverURL:"https://cdn.intechopen.com/books/images_new/10910.jpg",editedByType:"Edited by",editors:[{id:"103586",title:null,name:"Sandro",middleName:null,surname:"Misciagna",slug:"sandro-misciagna",fullName:"Sandro Misciagna"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10228",title:"Dyslexia",subtitle:null,isOpenForSubmission:!1,hash:"6b4060d23ac02fcb4a11313ec1c911c6",slug:"dyslexia",bookSignature:"Jonathan Glazzard and Samuel Stones",coverURL:"https://cdn.intechopen.com/books/images_new/10228.jpg",editedByType:"Edited by",editors:[{id:"294281",title:"Prof.",name:"Jonathan",middleName:null,surname:"Glazzard",slug:"jonathan-glazzard",fullName:"Jonathan Glazzard"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"6593",title:"Decision Making",subtitle:null,isOpenForSubmission:!1,hash:"88cae11440930f7ba788d5cfedec5979",slug:"decision-making",bookSignature:"Fausto Pedro García Márquez, Alberto Pliego Marugán and Mayorkinos Papaelias",coverURL:"https://cdn.intechopen.com/books/images_new/6593.jpg",editedByType:"Edited by",editors:[{id:"22844",title:"Prof.",name:"Fausto Pedro",middleName:null,surname:"García Márquez",slug:"fausto-pedro-garcia-marquez",fullName:"Fausto Pedro García Márquez"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"5878",title:"Learning Disabilities",subtitle:"An International Perspective",isOpenForSubmission:!1,hash:"233671027a40a86828b81f5f6094c4df",slug:"learning-disabilities-an-international-perspective",bookSignature:"Carolyn S. Ryan",coverURL:"https://cdn.intechopen.com/books/images_new/5878.jpg",editedByType:"Edited by",editors:[{id:"28738",title:"Dr.",name:"Carolyn S",middleName:null,surname:"Ryan",slug:"carolyn-s-ryan",fullName:"Carolyn S Ryan"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"715",title:"Learning Disabilities",subtitle:null,isOpenForSubmission:!1,hash:"7cf7910a2068cff1fdcdfd5ed3c25cc7",slug:"learning-disabilities",bookSignature:"Wichian Sittiprapaporn",coverURL:"https://cdn.intechopen.com/books/images_new/715.jpg",editedByType:"Edited by",editors:[{id:"73395",title:"Dr.",name:"Phakkharawat",middleName:null,surname:"Sittiprapaporn",slug:"phakkharawat-sittiprapaporn",fullName:"Phakkharawat Sittiprapaporn"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],booksByTopicTotal:6,seriesByTopicCollection:[],seriesByTopicTotal:0,mostCitedChapters:[{id:"31205",doi:"10.5772/31726",title:"Could Motor Development Be an Emergent Property of Vestibular Stimulation and Primary Reflex Inhibition? A Tentative Approach to Sensorimotor Therapy",slug:"could-motor-development-be-an-emergent-property-partly-of-vestibular-stimulation-and-primary-reflex-",totalDownloads:4248,totalCrossrefCites:4,totalDimensionsCites:5,abstract:null,book:{id:"715",slug:"learning-disabilities",title:"Learning Disabilities",fullTitle:"Learning Disabilities"},signatures:"Mats Niklasson",authors:[{id:"88435",title:"MSc.",name:"Mats",middleName:null,surname:"Niklasson",slug:"mats-niklasson",fullName:"Mats Niklasson"}]},{id:"31209",doi:"10.5772/34299",title:"Disability and Oral Health",slug:"disability-and-oral-health",totalDownloads:7116,totalCrossrefCites:5,totalDimensionsCites:5,abstract:null,book:{id:"715",slug:"learning-disabilities",title:"Learning Disabilities",fullTitle:"Learning Disabilities"},signatures:"Jenny Gallagher and Sasha Scambler",authors:[{id:"99560",title:"Dr",name:"Jenny",middleName:null,surname:"Gallagher",slug:"jenny-gallagher",fullName:"Jenny Gallagher"},{id:"151953",title:"Dr.",name:"Sasha",middleName:null,surname:"Scambler",slug:"sasha-scambler",fullName:"Sasha Scambler"}]},{id:"55805",doi:"10.5772/intechopen.69464",title:"Classification and Detection of Specific Language Impairments in Children Based on their Speech Skills",slug:"classification-and-detection-of-specific-language-impairments-in-children-based-on-their-speech-skil",totalDownloads:1675,totalCrossrefCites:2,totalDimensionsCites:5,abstract:"The ability to use the spoken language is one of the most important characteristics in child development. Speech is difficult to replace in real life, although there are several other options for communication. Inabilities to communicate with speech skills can isolate children from society, especially children with specific language impairments. This research study focused on a specific disorder, known as specific language impairment (SLI); in the Czech language, it is specifically known as developmental dysphasia (DD). One major problem is that this disorder is detected at a relatively late age. Early diagnosis is critical for successful speech therapy in children. The current chapter presents several different approaches to solve this issue, including a simple test for detecting this disorder. One approach involves the use of an original iPad application for detecting SLI based on the number of pronunciation errors in utterances. One advantage of this method is its simplicity; anyone can use it, including parents.",book:{id:"5878",slug:"learning-disabilities-an-international-perspective",title:"Learning Disabilities",fullTitle:"Learning Disabilities - An International Perspective"},signatures:"Pavel Grill and Jana Tučková",authors:[{id:"199652",title:"Ph.D.",name:"Pavel",middleName:null,surname:"Grill",slug:"pavel-grill",fullName:"Pavel Grill"}]},{id:"57766",doi:"10.5772/intechopen.72052",title:"Developing Automaticity in Children with Learning Disabilities: A Functional Perspective Part Two: Programme Methods and Materials",slug:"developing-automaticity-in-children-with-learning-disabilities-a-functional-perspective-part-two-pro",totalDownloads:1391,totalCrossrefCites:4,totalDimensionsCites:4,abstract:"This chapter is the second of two chapters in this book to describe an instructional programme based on Luria's theories, which can be used to develop basic skills and automaticity in reading, writing, and spelling. The first chapter focused on the programme's theory, and then described how assessment is used to develop an individual programme relating to both basic skill and fluency needs in reading, writing, and spelling. The process was illustrated with one detailed case study. The results of this case study (Child 1) are presented in the current chapter, together with the results of 13 children exposed to similar fluency-based interventions. The results of six children exposed to one or more systematic variations in programme implementation are then discussed. Case contrast analysis is used to highlight three variables affecting successful programme implementation, namely: consistent and regular exposure to phonological and phonic instruction to provide a foundation of basic skills on which the fluency interventions in the programme can be built; consistent implementation of methods designed to improve both reading fluency, and writing and spelling fluency, to produce the greatest likelihood of positive effects; and consistent support from parents in programme implementation to produce the greatest likelihood of positive effects.",book:{id:"5878",slug:"learning-disabilities-an-international-perspective",title:"Learning Disabilities",fullTitle:"Learning Disabilities - An International Perspective"},signatures:"Charles Potter",authors:[{id:"93190",title:"Dr.",name:"Charles",middleName:null,surname:"Potter",slug:"charles-potter",fullName:"Charles Potter"}]},{id:"31189",doi:"10.5772/30128",title:"Meeting the Needs of Twice-Exceptional Children in the Science Classroom",slug:"meeting-the-needs-of-twice-exceptional-children-in-the-science-classroom",totalDownloads:3017,totalCrossrefCites:2,totalDimensionsCites:3,abstract:null,book:{id:"715",slug:"learning-disabilities",title:"Learning Disabilities",fullTitle:"Learning Disabilities"},signatures:"Manabu Sumida",authors:[{id:"80976",title:"Dr.",name:"Manabu",middleName:null,surname:"Sumida",slug:"manabu-sumida",fullName:"Manabu Sumida"}]}],mostDownloadedChaptersLast30Days:[{id:"57054",title:"Specific Learning Disabilities: Response to Intervention",slug:"specific-learning-disabilities-response-to-intervention",totalDownloads:2118,totalCrossrefCites:1,totalDimensionsCites:2,abstract:"The content included in the current chapter centers around the screening and identification of students who experience learning challenges in an educational setting in the United States of America. The specific learning challenges discussed will focus on students who may have a specific learning disability (SLD). Legislation that brought about concepts such as response to intervention (RTI) is discussed in detail. The various levels of intensity of interventions, or tiers, provided to students are explained by more than one discipline. The new regulations guiding access to special education services are based on the identification, intervention, and close monitoring of student progress. The overarching goal of RTI is to provide support to students who may be experiencing difficulty, before they experience failure by falling too far behind their peers.",book:{id:"5878",slug:"learning-disabilities-an-international-perspective",title:"Learning Disabilities",fullTitle:"Learning Disabilities - An International Perspective"},signatures:"Kimberly A. Heinemann, Heather Bolanos and Jennifer S. Griffin",authors:[{id:"205622",title:"Mrs.",name:"Kimberly",middleName:null,surname:"Heinemann",slug:"kimberly-heinemann",fullName:"Kimberly Heinemann"},{id:"208681",title:"Mrs.",name:"Heather",middleName:null,surname:"Bolanos",slug:"heather-bolanos",fullName:"Heather Bolanos"},{id:"208691",title:"Mrs.",name:"Jennifer S.",middleName:null,surname:"Griffin",slug:"jennifer-s.-griffin",fullName:"Jennifer S. Griffin"}]},{id:"59913",title:"Decision-Making in Complex Dynamic and Evolutive Systems: The Need for a New Paradigm",slug:"decision-making-in-complex-dynamic-and-evolutive-systems-the-need-for-a-new-paradigm",totalDownloads:4566,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"For contemporary psychology, decision-making represents behaviours, which are very different from automatic responses. They are developed by implementing integrative cognitive functions adapted to the finalities sought and the situation to treat. Through the diversity of epistemological choices for instance, research in previous decades focused on the individual choices expressed by situations or contexts with a stable structure. The new problems of life in today’s society lead to making decisions on societal problems (climate, energy, etc.), which bring into play systems and no longer variables. This chapter has four aspects. After having characterised the decision-making process as a cognitive behaviour (1), having recalled the best known traditional models (those of Economics and Psychology) (2), this chapter deals with the properties of complex systems (globality, interactivity, dynamism, and scalability), which render decision-making difficult (3), and concludes with the necessity of a change of paradigm by pointing to paths to follow (4).",book:{id:"6593",slug:"decision-making",title:"Decision Making",fullTitle:"Decision Making"},signatures:"Bernard Cadet",authors:[{id:"232726",title:"Emeritus Prof.",name:"Bernard",middleName:null,surname:"Cadet",slug:"bernard-cadet",fullName:"Bernard Cadet"}]},{id:"63337",title:"Introductory Chapter: An Overview to the Analytic Principles with Business Practice in Decision Making",slug:"introductory-chapter-an-overview-to-the-analytic-principles-with-business-practice-in-decision-makin",totalDownloads:917,totalCrossrefCites:0,totalDimensionsCites:1,abstract:null,book:{id:"6593",slug:"decision-making",title:"Decision Making",fullTitle:"Decision Making"},signatures:"Fausto Pedro García Márquez, Alberto Pliego Marugán and\nMayorkinos Papaelias",authors:[{id:"22844",title:"Prof.",name:"Fausto Pedro",middleName:null,surname:"García Márquez",slug:"fausto-pedro-garcia-marquez",fullName:"Fausto Pedro García Márquez"}]},{id:"80202",title:"Depression, Suicidal Tendencies, Hopelessness, and Stress among Patients with Learning Disabilities",slug:"depression-suicidal-tendencies-hopelessness-and-stress-among-patients-with-learning-disabilities",totalDownloads:96,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"Self-harm and suicide are most commonly observed in adolescents specially females in Asian countries and in western. The psychosocial predictors, along with hopelessness and non-suicidal injury (NSSI), have not been studied properly before. Therefore, there is a need to address these issues. The objective of the study was to ascertain the psychosocial and clinical features predicting suicide and NSSI in adolescents with major depression. Increased number of suicidality and impaired family function at entry is autonomously connected with a suicidal attempt. NSSI are connected at base line and apply additive effect on likelihood, one keeping on through treatment period. Poor family functions, as well as family problems and social problems, were the causative agents for adolescent’s high suicidality and NSSI. A history of NSSI treatment is a clinical marker for suicidality. The previous suicidal attempts should be evaluated in depressed juvenile patients as indicators of future suicidal intent and behavior. Both suicidal and NSSI adolescents during the therapy and after treatment endure to be depressed when they are engaged in study. Major causes of suicide among our study participants were lost friend(s), drug abuse, living alone, disturbed parental marriage, sexual abuse, and other domestic problems.",book:{id:"10910",slug:"learning-disabilities-neurobiology-assessment-clinical-features-and-treatments",title:"Learning Disabilities",fullTitle:"Learning Disabilities - Neurobiology, Assessment, Clinical Features and Treatments"},signatures:"Fahad Hassan Shah, Song Ja Kim, Laiba Zakir, Aqsa Ehsan, Sohail Riaz, Muhammad Sulaiman and Saad Salman",authors:[{id:"418086",title:"Dr.",name:"Saad",middleName:null,surname:"Salman",slug:"saad-salman",fullName:"Saad Salman"},{id:"439291",title:"Dr.",name:"Fahad Hassan",middleName:null,surname:"Shah",slug:"fahad-hassan-shah",fullName:"Fahad Hassan Shah"},{id:"439292",title:"Dr.",name:"Song Ja",middleName:null,surname:"Kim",slug:"song-ja-kim",fullName:"Song Ja Kim"},{id:"439293",title:"Dr.",name:"Laiba",middleName:null,surname:"Zakir",slug:"laiba-zakir",fullName:"Laiba Zakir"},{id:"439294",title:"Dr.",name:"Aqsa",middleName:null,surname:"Ehsan",slug:"aqsa-ehsan",fullName:"Aqsa Ehsan"},{id:"451112",title:"Dr.",name:"Sohail",middleName:null,surname:"Riaz",slug:"sohail-riaz",fullName:"Sohail Riaz"},{id:"451113",title:"Dr.",name:"Muhammad",middleName:null,surname:"Sulaiman",slug:"muhammad-sulaiman",fullName:"Muhammad Sulaiman"}]},{id:"79900",title:"Dyslexia, Dysgraphia and Dyscalculia: A Response to Intervention Approach to Classification",slug:"dyslexia-dysgraphia-and-dyscalculia-a-response-to-intervention-approach-to-classification",totalDownloads:150,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"This chapter provides a model for classification of dyslexia, dysgraphia and dyscalculia through analysis of the response of children to treatment. The model is discussed with reference to the types of multivariate treatment applied in a particular programme which works interactively online using an electronic data-base for linking functional difficulties in learning to treatment, and through this to firm diagnosis and classification. In applying the model, initial diagnosis of learning disabilities is treated as provisional, based on functional indicators as well as test data. Firm classification becomes possible through longitudinal assessment, analysis of response to multivariate intervention as well as response to specific programmes. Diagnosis can then be linked both to concessions as well as ongoing treatment.",book:{id:"10910",slug:"learning-disabilities-neurobiology-assessment-clinical-features-and-treatments",title:"Learning Disabilities",fullTitle:"Learning Disabilities - Neurobiology, Assessment, Clinical Features and Treatments"},signatures:"Charles Potter",authors:[{id:"93190",title:"Dr.",name:"Charles",middleName:null,surname:"Potter",slug:"charles-potter",fullName:"Charles Potter"}]}],onlineFirstChaptersFilter:{topicId:"233",limit:6,offset:0},onlineFirstChaptersCollection:[],onlineFirstChaptersTotal:0},preDownload:{success:null,errors:{}},subscriptionForm:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[],offset:8,limit:8,total:0},allSeries:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:8,numberOfPublishedChapters:87,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:98,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:27,numberOfPublishedChapters:286,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:9,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:11,numberOfPublishedChapters:139,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:8,numberOfPublishedChapters:129,numberOfOpenTopics:0,numberOfUpcomingTopics:2,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!1},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:105,numberOfOpenTopics:3,numberOfUpcomingTopics:1,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:9,numberOfPublishedChapters:101,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:11,numberOfOpenTopics:2,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:0,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!1},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:0,numberOfPublishedChapters:9,numberOfOpenTopics:4,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],testimonialsList:[{id:"6",text:"It is great to work with the IntechOpen to produce a worthwhile collection of research that also becomes a great educational resource and guide for future research endeavors.",author:{id:"259298",name:"Edward",surname:"Narayan",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259298/images/system/259298.jpeg",slug:"edward-narayan",institution:{id:"3",name:"University of Queensland",country:{id:null,name:"Australia"}}}},{id:"13",text:"The collaboration with and support of the technical staff of IntechOpen is fantastic. The whole process of submitting an article and editing of the submitted article goes extremely smooth and fast, the number of reads and downloads of chapters is high, and the contributions are also frequently cited.",author:{id:"55578",name:"Antonio",surname:"Jurado-Navas",institutionString:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRisIQAS/Profile_Picture_1626166543950",slug:"antonio-jurado-navas",institution:{id:"720",name:"University of Malaga",country:{id:null,name:"Spain"}}}}]},series:{item:{id:"11",title:"Biochemistry",doi:"10.5772/intechopen.72877",issn:"2632-0983",scope:"Biochemistry, the study of chemical transformations occurring within living organisms, impacts all areas of life sciences, from molecular crystallography and genetics to ecology, medicine, and population biology. Biochemistry examines macromolecules - proteins, nucleic acids, carbohydrates, and lipids – and their building blocks, structures, functions, and interactions. Much of biochemistry is devoted to enzymes, proteins that catalyze chemical reactions, enzyme structures, mechanisms of action and their roles within cells. Biochemistry also studies small signaling molecules, coenzymes, inhibitors, vitamins, and hormones, which play roles in life processes. Biochemical experimentation, besides coopting classical chemistry methods, e.g., chromatography, adopted new techniques, e.g., X-ray diffraction, electron microscopy, NMR, radioisotopes, and developed sophisticated microbial genetic tools, e.g., auxotroph mutants and their revertants, fermentation, etc. More recently, biochemistry embraced the ‘big data’ omics systems. Initial biochemical studies have been exclusively analytic: dissecting, purifying, and examining individual components of a biological system; in the apt words of Efraim Racker (1913 –1991), “Don’t waste clean thinking on dirty enzymes.” Today, however, biochemistry is becoming more agglomerative and comprehensive, setting out to integrate and describe entirely particular biological systems. The ‘big data’ metabolomics can define the complement of small molecules, e.g., in a soil or biofilm sample; proteomics can distinguish all the comprising proteins, e.g., serum; metagenomics can identify all the genes in a complex environment, e.g., the bovine rumen. This Biochemistry Series will address the current research on biomolecules and the emerging trends with great promise.",coverUrl:"https://cdn.intechopen.com/series/covers/11.jpg",latestPublicationDate:"May 15th, 2022",hasOnlineFirst:!0,numberOfPublishedBooks:27,editor:{id:"31610",title:"Dr.",name:"Miroslav",middleName:null,surname:"Blumenberg",slug:"miroslav-blumenberg",fullName:"Miroslav Blumenberg",profilePictureURL:"https://mts.intechopen.com/storage/users/31610/images/system/31610.jpg",biography:"Miroslav Blumenberg, Ph.D., was born in Subotica and received his BSc in Belgrade, Yugoslavia. He completed his Ph.D. at MIT in Organic Chemistry; he followed up his Ph.D. with two postdoctoral study periods at Stanford University. Since 1983, he has been a faculty member of the RO Perelman Department of Dermatology, NYU School of Medicine, where he is codirector of a training grant in cutaneous biology. Dr. Blumenberg’s research is focused on the epidermis, expression of keratin genes, transcription profiling, keratinocyte differentiation, inflammatory diseases and cancers, and most recently the effects of the microbiome on the skin. He has published more than 100 peer-reviewed research articles and graduated numerous Ph.D. and postdoctoral students.",institutionString:null,institution:{name:"New York University Langone Medical Center",institutionURL:null,country:{name:"United States of America"}}},editorTwo:null,editorThree:null},subseries:{paginationCount:4,paginationItems:[{id:"14",title:"Cell and Molecular Biology",coverUrl:"https://cdn.intechopen.com/series_topics/covers/14.jpg",isOpenForSubmission:!0,annualVolume:11410,editor:{id:"165627",title:"Dr.",name:"Rosa María",middleName:null,surname:"Martínez-Espinosa",slug:"rosa-maria-martinez-espinosa",fullName:"Rosa María Martínez-Espinosa",profilePictureURL:"https://mts.intechopen.com/storage/users/165627/images/system/165627.jpeg",biography:"Dr. Rosa María Martínez-Espinosa has been a Spanish Full Professor since 2020 (Biochemistry and Molecular Biology) and is currently Vice-President of International Relations and Cooperation development and leader of the research group 'Applied Biochemistry” (University of Alicante, Spain). Other positions she has held at the university include Vice-Dean of Master Programs, Vice-Dean of the Degree in Biology and Vice-Dean for Mobility and Enterprise and Engagement at the Faculty of Science (University of Alicante). She received her Bachelor in Biology in 1998 (University of Alicante) and her PhD in 2003 (Biochemistry, University of Alicante). She undertook post-doctoral research at the University of East Anglia (Norwich, U.K. 2004-2005; 2007-2008).\nHer multidisciplinary research focuses on investigating archaea and their potential applications in biotechnology. She has an H-index of 21. She has authored one patent and has published more than 70 indexed papers and around 60 book chapters.\nShe has contributed to more than 150 national and international meetings during the last 15 years. Her research interests include archaea metabolism, enzymes purification and characterization, gene regulation, carotenoids and bioplastics production, antioxidant\ncompounds, waste water treatments, and brines bioremediation.\nRosa María’s other roles include editorial board member for several journals related\nto biochemistry, reviewer for more than 60 journals (biochemistry, molecular biology, biotechnology, chemistry and microbiology) and president of several organizing committees in international meetings related to the N-cycle or respiratory processes.",institutionString:null,institution:{name:"University of Alicante",institutionURL:null,country:{name:"Spain"}}},editorTwo:null,editorThree:null},{id:"15",title:"Chemical Biology",coverUrl:"https://cdn.intechopen.com/series_topics/covers/15.jpg",isOpenForSubmission:!0,annualVolume:11411,editor:{id:"441442",title:"Dr.",name:"Şükrü",middleName:null,surname:"Beydemir",slug:"sukru-beydemir",fullName:"Şükrü Beydemir",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00003GsUoIQAV/Profile_Picture_1634557147521",biography:"Dr. Şükrü Beydemir obtained a BSc in Chemistry in 1995 from Yüzüncü Yıl University, MSc in Biochemistry in 1998, and PhD in Biochemistry in 2002 from Atatürk University, Turkey. He performed post-doctoral studies at Max-Planck Institute, Germany, and University of Florence, Italy in addition to making several scientific visits abroad. He currently works as a Full Professor of Biochemistry in the Faculty of Pharmacy, Anadolu University, Turkey. Dr. Beydemir has published over a hundred scientific papers spanning protein biochemistry, enzymology and medicinal chemistry, reviews, book chapters and presented several conferences to scientists worldwide. He has received numerous publication awards from various international scientific councils. He serves in the Editorial Board of several international journals. Dr. Beydemir is also Rector of Bilecik Şeyh Edebali University, Turkey.",institutionString:null,institution:{name:"Anadolu University",institutionURL:null,country:{name:"Turkey"}}},editorTwo:{id:"13652",title:"Prof.",name:"Deniz",middleName:null,surname:"Ekinci",slug:"deniz-ekinci",fullName:"Deniz Ekinci",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYLT1QAO/Profile_Picture_1634557223079",biography:"Dr. Deniz Ekinci obtained a BSc in Chemistry in 2004, MSc in Biochemistry in 2006, and PhD in Biochemistry in 2009 from Atatürk University, Turkey. He studied at Stetson University, USA, in 2007-2008 and at the Max Planck Institute of Molecular Cell Biology and Genetics, Germany, in 2009-2010. Dr. Ekinci currently works as a Full Professor of Biochemistry in the Faculty of Agriculture and is the Head of the Enzyme and Microbial Biotechnology Division, Ondokuz Mayıs University, Turkey. He is a member of the Turkish Biochemical Society, American Chemical Society, and German Genetics society. Dr. Ekinci published around ninety scientific papers, reviews and book chapters, and presented several conferences to scientists. He has received numerous publication awards from several scientific councils. Dr. Ekinci serves as the Editor in Chief of four international books and is involved in the Editorial Board of several international journals.",institutionString:null,institution:{name:"Ondokuz Mayıs University",institutionURL:null,country:{name:"Turkey"}}},editorThree:null},{id:"17",title:"Metabolism",coverUrl:"https://cdn.intechopen.com/series_topics/covers/17.jpg",isOpenForSubmission:!0,annualVolume:11413,editor:{id:"138626",title:"Dr.",name:"Yannis",middleName:null,surname:"Karamanos",slug:"yannis-karamanos",fullName:"Yannis Karamanos",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002g6Jv2QAE/Profile_Picture_1629356660984",biography:"Yannis Karamanos, born in Greece in 1953, completed his pre-graduate studies at the Université Pierre et Marie Curie, Paris, then his Masters and Doctoral degree at the Université de Lille (1983). He was associate professor at the University of Limoges (1987) before becoming full professor of biochemistry at the Université d’Artois (1996). He worked on the structure-function relationships of glycoconjugates and his main project was the investigations on the biological roles of the de-N-glycosylation enzymes (Endo-N-acetyl-β-D-glucosaminidase and peptide-N4-(N-acetyl-β-glucosaminyl) asparagine amidase). From 2002 he contributes to the understanding of the Blood-brain barrier functioning using proteomics approaches. He has published more than 70 papers. His teaching areas are energy metabolism and regulation, integration and organ specialization and metabolic adaptation.",institutionString:null,institution:{name:"Artois University",institutionURL:null,country:{name:"France"}}},editorTwo:null,editorThree:null},{id:"18",title:"Proteomics",coverUrl:"https://cdn.intechopen.com/series_topics/covers/18.jpg",isOpenForSubmission:!0,annualVolume:11414,editor:{id:"200689",title:"Prof.",name:"Paolo",middleName:null,surname:"Iadarola",slug:"paolo-iadarola",fullName:"Paolo Iadarola",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSCl8QAG/Profile_Picture_1623568118342",biography:"Paolo Iadarola graduated with a degree in Chemistry from the University of Pavia (Italy) in July 1972. He then worked as an Assistant Professor at the Faculty of Science of the same University until 1984. In 1985, Prof. Iadarola became Associate Professor at the Department of Biology and Biotechnologies of the University of Pavia and retired in October 2017. Since then, he has been working as an Adjunct Professor in the same Department at the University of Pavia. His research activity during the first years was primarily focused on the purification and structural characterization of enzymes from animal and plant sources. During this period, Prof. Iadarola familiarized himself with the conventional techniques used in column chromatography, spectrophotometry, manual Edman degradation, and electrophoresis). Since 1995, he has been working on: i) the determination in biological fluids (serum, urine, bronchoalveolar lavage, sputum) of proteolytic activities involved in the degradation processes of connective tissue matrix, and ii) on the identification of biological markers of lung diseases. In this context, he has developed and validated new methodologies (e.g., Capillary Electrophoresis coupled to Laser-Induced Fluorescence, CE-LIF) whose application enabled him to determine both the amounts of biochemical markers (Desmosines) in urine/serum of patients affected by Chronic Obstructive Pulmonary Disease (COPD) and the activity of proteolytic enzymes (Human Neutrophil Elastase, Cathepsin G, Pseudomonas aeruginosa elastase) in sputa of these patients. More recently, Prof. Iadarola was involved in developing techniques such as two-dimensional electrophoresis coupled to liquid chromatography/mass spectrometry (2DE-LC/MS) for the proteomic analysis of biological fluids aimed at the identification of potential biomarkers of different lung diseases. He is the author of about 150 publications (According to Scopus: H-Index: 23; Total citations: 1568- According to WOS: H-Index: 20; Total Citations: 1296) of peer-reviewed international journals. He is a Consultant Reviewer for several journals, including the Journal of Chromatography A, Journal of Chromatography B, Plos ONE, Proteomes, International Journal of Molecular Science, Biotech, Electrophoresis, and others. He is also Associate Editor of Biotech.",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorTwo:{id:"201414",title:"Dr.",name:"Simona",middleName:null,surname:"Viglio",slug:"simona-viglio",fullName:"Simona Viglio",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRKDHQA4/Profile_Picture_1630402531487",biography:"Simona Viglio is an Associate Professor of Biochemistry at the Department of Molecular Medicine at the University of Pavia. She has been working since 1995 on the determination of proteolytic enzymes involved in the degradation process of connective tissue matrix and on the identification of biological markers of lung diseases. She gained considerable experience in developing and validating new methodologies whose applications allowed her to determine both the amount of biomarkers (Desmosine and Isodesmosine) in the urine of patients affected by COPD, and the activity of proteolytic enzymes (HNE, Cathepsin G, Pseudomonas aeruginosa elastase) in the sputa of these patients. Simona Viglio was also involved in research dealing with the supplementation of amino acids in patients with brain injury and chronic heart failure. She is presently engaged in the development of 2-DE and LC-MS techniques for the study of proteomics in biological fluids. The aim of this research is the identification of potential biomarkers of lung diseases. She is an author of about 90 publications (According to Scopus: H-Index: 23; According to WOS: H-Index: 20) on peer-reviewed journals, a member of the “Società Italiana di Biochimica e Biologia Molecolare,“ and a Consultant Reviewer for International Journal of Molecular Science, Journal of Chromatography A, COPD, Plos ONE and Nutritional Neuroscience.",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorThree:null}]},overviewPageOFChapters:{paginationCount:48,paginationItems:[{id:"81799",title:"Cross Talk of Purinergic and Immune Signaling: Implication in Inflammatory and Pathogenic Diseases",doi:"10.5772/intechopen.104978",signatures:"Richa Rai",slug:"cross-talk-of-purinergic-and-immune-signaling-implication-in-inflammatory-and-pathogenic-diseases",totalDownloads:3,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Purinergic System",coverURL:"https://cdn.intechopen.com/books/images_new/10801.jpg",subseries:{id:"17",title:"Metabolism"}}},{id:"81764",title:"Involvement of the Purinergic System in Cell Death in Models of Retinopathies",doi:"10.5772/intechopen.103935",signatures:"Douglas Penaforte Cruz, Marinna Garcia Repossi and Lucianne Fragel Madeira",slug:"involvement-of-the-purinergic-system-in-cell-death-in-models-of-retinopathies",totalDownloads:3,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Purinergic System",coverURL:"https://cdn.intechopen.com/books/images_new/10801.jpg",subseries:{id:"17",title:"Metabolism"}}},{id:"81756",title:"Alteration of Cytokines Level and Oxidative Stress Parameters in COVID-19",doi:"10.5772/intechopen.104950",signatures:"Marija Petrusevska, Emilija Atanasovska, Dragica Zendelovska, Aleksandar Eftimov and Katerina Spasovska",slug:"alteration-of-cytokines-level-and-oxidative-stress-parameters-in-covid-19",totalDownloads:5,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Chemokines Updates",coverURL:"https://cdn.intechopen.com/books/images_new/11672.jpg",subseries:{id:"18",title:"Proteomics"}}},{id:"81681",title:"Immunomodulatory Effects of a M2-Conditioned Medium (PRS® CK STORM): Theory on the Possible Complex Mechanism of Action through Anti-Inflammatory Modulation of the TLR System and the Purinergic System",doi:"10.5772/intechopen.104486",signatures:"Juan Pedro Lapuente",slug:"immunomodulatory-effects-of-a-m2-conditioned-medium-prs-ck-storm-theory-on-the-possible-complex-mech",totalDownloads:5,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Purinergic System",coverURL:"https://cdn.intechopen.com/books/images_new/10801.jpg",subseries:{id:"17",title:"Metabolism"}}}]},overviewPagePublishedBooks:{paginationCount:27,paginationItems:[{type:"book",id:"7006",title:"Biochemistry and Health Benefits of Fatty Acids",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7006.jpg",slug:"biochemistry-and-health-benefits-of-fatty-acids",publishedDate:"December 19th 2018",editedByType:"Edited by",bookSignature:"Viduranga Waisundara",hash:"c93a00abd68b5eba67e5e719f67fd20b",volumeInSeries:1,fullTitle:"Biochemistry and Health Benefits of Fatty Acids",editors:[{id:"194281",title:"Dr.",name:"Viduranga Y.",middleName:null,surname:"Waisundara",slug:"viduranga-y.-waisundara",fullName:"Viduranga Y. Waisundara",profilePictureURL:"https://mts.intechopen.com/storage/users/194281/images/system/194281.jpg",biography:"Dr. Viduranga Waisundara obtained her Ph.D. in Food Science and Technology from the Department of Chemistry, National University of Singapore, in 2010. She was a lecturer at Temasek Polytechnic, Singapore from July 2009 to March 2013. She relocated to her motherland of Sri Lanka and spearheaded the Functional Food Product Development Project at the National Institute of Fundamental Studies from April 2013 to October 2016. She was a senior lecturer on a temporary basis at the Department of Food Technology, Faculty of Technology, Rajarata University of Sri Lanka. She is currently Deputy Principal of the Australian College of Business and Technology – Kandy Campus, Sri Lanka. She is also the Global Harmonization Initiative (GHI) Ambassador to Sri Lanka.",institutionString:"Australian College of Business & Technology",institution:null}]},{type:"book",id:"6820",title:"Keratin",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/6820.jpg",slug:"keratin",publishedDate:"December 19th 2018",editedByType:"Edited by",bookSignature:"Miroslav Blumenberg",hash:"6def75cd4b6b5324a02b6dc0359896d0",volumeInSeries:2,fullTitle:"Keratin",editors:[{id:"31610",title:"Dr.",name:"Miroslav",middleName:null,surname:"Blumenberg",slug:"miroslav-blumenberg",fullName:"Miroslav Blumenberg",profilePictureURL:"https://mts.intechopen.com/storage/users/31610/images/system/31610.jpg",biography:"Miroslav Blumenberg, Ph.D., was born in Subotica and received his BSc in Belgrade, Yugoslavia. He completed his Ph.D. at MIT in Organic Chemistry; he followed up his Ph.D. with two postdoctoral study periods at Stanford University. Since 1983, he has been a faculty member of the RO Perelman Department of Dermatology, NYU School of Medicine, where he is codirector of a training grant in cutaneous biology. Dr. Blumenberg’s research is focused on the epidermis, expression of keratin genes, transcription profiling, keratinocyte differentiation, inflammatory diseases and cancers, and most recently the effects of the microbiome on the skin. He has published more than 100 peer-reviewed research articles and graduated numerous Ph.D. and postdoctoral students.",institutionString:null,institution:{name:"New York University Langone Medical Center",institutionURL:null,country:{name:"United States of America"}}}]},{type:"book",id:"7978",title:"Vitamin A",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7978.jpg",slug:"vitamin-a",publishedDate:"May 15th 2019",editedByType:"Edited by",bookSignature:"Leila Queiroz Zepka, Veridiana Vera de Rosso and Eduardo Jacob-Lopes",hash:"dad04a658ab9e3d851d23705980a688b",volumeInSeries:3,fullTitle:"Vitamin A",editors:[{id:"261969",title:"Dr.",name:"Leila",middleName:null,surname:"Queiroz Zepka",slug:"leila-queiroz-zepka",fullName:"Leila Queiroz Zepka",profilePictureURL:"https://mts.intechopen.com/storage/users/261969/images/system/261969.png",biography:"Prof. Dr. Leila Queiroz Zepka is currently an associate professor in the Department of Food Technology and Science, Federal University of Santa Maria, Brazil. She has more than fifteen years of teaching and research experience. She has published more than 550 scientific publications/communications, including 15 books, 50 book chapters, 100 original research papers, 380 research communications in national and international conferences, and 12 patents. She is a member of the editorial board of five journals and acts as a reviewer for several national and international journals. Her research interests include microalgal biotechnology with an emphasis on microalgae-based products.",institutionString:"Universidade Federal de Santa Maria",institution:{name:"Universidade Federal de Santa Maria",institutionURL:null,country:{name:"Brazil"}}}]},{type:"book",id:"7953",title:"Bioluminescence",subtitle:"Analytical Applications and Basic Biology",coverURL:"https://cdn.intechopen.com/books/images_new/7953.jpg",slug:"bioluminescence-analytical-applications-and-basic-biology",publishedDate:"September 25th 2019",editedByType:"Edited by",bookSignature:"Hirobumi Suzuki",hash:"3a8efa00b71abea11bf01973dc589979",volumeInSeries:4,fullTitle:"Bioluminescence - Analytical Applications and Basic Biology",editors:[{id:"185746",title:"Dr.",name:"Hirobumi",middleName:null,surname:"Suzuki",slug:"hirobumi-suzuki",fullName:"Hirobumi Suzuki",profilePictureURL:"https://mts.intechopen.com/storage/users/185746/images/system/185746.png",biography:"Dr. Hirobumi Suzuki received his Ph.D. in 1997 from Tokyo Metropolitan University, Japan, where he studied firefly phylogeny and the evolution of mating systems. He is especially interested in the genetic differentiation pattern and speciation process that correlate to the flashing pattern and mating behavior of some fireflies in Japan. He then worked for Olympus Corporation, a Japanese manufacturer of optics and imaging products, where he was involved in the development of luminescence technology and produced a bioluminescence microscope that is currently being used for gene expression analysis in chronobiology, neurobiology, and developmental biology. Dr. Suzuki currently serves as a visiting researcher at Kogakuin University, Japan, and also a vice president of the Japan Firefly Society.",institutionString:"Kogakuin University",institution:null}]}]},openForSubmissionBooks:{paginationCount:6,paginationItems:[{id:"11671",title:"Importance of Oxidative Stress and Antioxidant System in Health and Disease",coverURL:"https://cdn.intechopen.com/books/images_new/11671.jpg",hash:"2bd98244cd9eda2107f01824584c1eb4",secondStepPassed:!0,currentStepOfPublishingProcess:4,submissionDeadline:"March 17th 2022",isOpenForSubmission:!0,editors:[{id:"270856",title:"Associate Prof.",name:"Suna",surname:"Sabuncuoglu",slug:"suna-sabuncuoglu",fullName:"Suna Sabuncuoglu"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{id:"11669",title:"Fatty Acids - Recent Advances",coverURL:"https://cdn.intechopen.com/books/images_new/11669.jpg",hash:"9117bd12dc904ced43404e3383b6591a",secondStepPassed:!0,currentStepOfPublishingProcess:3,submissionDeadline:"May 3rd 2022",isOpenForSubmission:!0,editors:[{id:"415310",title:"Assistant Prof.",name:"Erik",surname:"Froyen",slug:"erik-froyen",fullName:"Erik Froyen"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{id:"11672",title:"Chemokines Updates",coverURL:"https://cdn.intechopen.com/books/images_new/11672.jpg",hash:"c00855833476a514d37abf7c846e16e9",secondStepPassed:!0,currentStepOfPublishingProcess:3,submissionDeadline:"May 6th 2022",isOpenForSubmission:!0,editors:[{id:"14794",title:"Prof.",name:"Murat",surname:"Şentürk",slug:"murat-senturk",fullName:"Murat Şentürk"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{id:"11674",title:"Updates on Endoplasmic Reticulum",coverURL:"https://cdn.intechopen.com/books/images_new/11674.jpg",hash:"5d7d49bd80f53dad3761f78de4a862c6",secondStepPassed:!0,currentStepOfPublishingProcess:3,submissionDeadline:"May 6th 2022",isOpenForSubmission:!0,editors:[{id:"238047",title:"Dr.",name:"Gaia",surname:"Favero",slug:"gaia-favero",fullName:"Gaia Favero"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{id:"11670",title:"Chitin-Chitosan - Isolation, Properties, and Applications",coverURL:"https://cdn.intechopen.com/books/images_new/11670.jpg",hash:"69f009be08998711eecfb200adc7deca",secondStepPassed:!1,currentStepOfPublishingProcess:2,submissionDeadline:"May 26th 2022",isOpenForSubmission:!0,editors:[{id:"176093",title:"Dr.",name:"Brajesh",surname:"Kumar",slug:"brajesh-kumar",fullName:"Brajesh Kumar"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{id:"11673",title:"Stem Cell Research",coverURL:"https://cdn.intechopen.com/books/images_new/11673.jpg",hash:"13092df328080c762dd9157be18ca38c",secondStepPassed:!1,currentStepOfPublishingProcess:2,submissionDeadline:"June 8th 2022",isOpenForSubmission:!0,editors:[{id:"203598",title:"Ph.D.",name:"Diana",surname:"Kitala",slug:"diana-kitala",fullName:"Diana Kitala"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null}]},onlineFirstChapters:{paginationCount:26,paginationItems:[{id:"81791",title:"Self-Supervised Contrastive Representation Learning in Computer Vision",doi:"10.5772/intechopen.104785",signatures:"Yalin Bastanlar and Semih Orhan",slug:"self-supervised-contrastive-representation-learning-in-computer-vision",totalDownloads:1,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Pattern Recognition - New Insights",coverURL:"https://cdn.intechopen.com/books/images_new/11442.jpg",subseries:{id:"26",title:"Machine Learning and Data Mining"}}},{id:"79345",title:"Application of Jump Diffusion Models in Insurance Claim Estimation",doi:"10.5772/intechopen.99853",signatures:"Leonard Mushunje, Chiedza Elvina Mashiri, Edina Chandiwana and Maxwell Mashasha",slug:"application-of-jump-diffusion-models-in-insurance-claim-estimation-1",totalDownloads:2,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Data Clustering",coverURL:"https://cdn.intechopen.com/books/images_new/10820.jpg",subseries:{id:"26",title:"Machine Learning and Data Mining"}}},{id:"81557",title:"Object Tracking Using Adapted Optical Flow",doi:"10.5772/intechopen.102863",signatures:"Ronaldo Ferreira, Joaquim José de Castro Ferreira and António José Ribeiro Neves",slug:"object-tracking-using-adapted-optical-flow",totalDownloads:10,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Information Extraction and Object Tracking in Digital Video",coverURL:"https://cdn.intechopen.com/books/images_new/10652.jpg",subseries:{id:"24",title:"Computer Vision"}}},{id:"81558",title:"Thresholding Image Techniques for Plant Segmentation",doi:"10.5772/intechopen.104587",signatures:"Miguel Ángel Castillo-Martínez, Francisco Javier Gallegos-Funes, Blanca E. Carvajal-Gámez, Guillermo Urriolagoitia-Sosa and Alberto J. Rosales-Silva",slug:"thresholding-image-techniques-for-plant-segmentation",totalDownloads:13,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Information Extraction and Object Tracking in Digital Video",coverURL:"https://cdn.intechopen.com/books/images_new/10652.jpg",subseries:{id:"24",title:"Computer Vision"}}},{id:"81471",title:"Semantic Map: Bringing Together Groups and Discourses",doi:"10.5772/intechopen.103818",signatures:"Theodore Chadjipadelis and Georgia Panagiotidou",slug:"semantic-map-bringing-together-groups-and-discourses",totalDownloads:11,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Data Clustering",coverURL:"https://cdn.intechopen.com/books/images_new/10820.jpg",subseries:{id:"26",title:"Machine Learning and Data Mining"}}},{id:"79491",title:"Fuzzy Perceptron Learning for Non-Linearly Separable Patterns",doi:"10.5772/intechopen.101312",signatures:"Raja Kishor Duggirala",slug:"fuzzy-perceptron-learning-for-non-linearly-separable-patterns",totalDownloads:13,totalCrossrefCites:0,totalDimensionsCites:0,authors:[{name:"Raja Kishor",surname:"Duggirala"}],book:{title:"Data Clustering",coverURL:"https://cdn.intechopen.com/books/images_new/10820.jpg",subseries:{id:"26",title:"Machine Learning and Data Mining"}}},{id:"81234",title:"Cognitive Visual Tracking of Hand Gestures in Real-Time RGB Videos",doi:"10.5772/intechopen.103170",signatures:"Richa Golash and Yogendra Kumar Jain",slug:"cognitive-visual-tracking-of-hand-gestures-in-real-time-rgb-videos",totalDownloads:11,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Information Extraction and Object Tracking in Digital Video",coverURL:"https://cdn.intechopen.com/books/images_new/10652.jpg",subseries:{id:"24",title:"Computer Vision"}}},{id:"81331",title:"Machine Learning Algorithm-Based Contraceptive Practice among Ever-Married Women in Bangladesh: A Hierarchical Machine Learning Classification Approach",doi:"10.5772/intechopen.103187",signatures:"Iqramul Haq, Md. Ismail Hossain, Md. Moshiur Rahman, Md. Injamul Haq Methun, Ashis Talukder, Md. Jakaria Habib and Md. Sanwar Hossain",slug:"machine-learning-algorithm-based-contraceptive-practice-among-ever-married-women-in-bangladesh-a-hie",totalDownloads:18,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Machine Learning and Data Mining - Annual Volume 2022",coverURL:"https://cdn.intechopen.com/books/images_new/11422.jpg",subseries:{id:"26",title:"Machine Learning and Data Mining"}}},{id:"81321",title:"Velocity Planning via Model-Based Reinforcement Learning: Demonstrating Results on PILCO for One-Dimensional Linear Motion with Bounded Acceleration",doi:"10.5772/intechopen.103690",signatures:"Hsuan-Cheng Liao, Han-Jung Chou and Jing-Sin Liu",slug:"velocity-planning-via-model-based-reinforcement-learning-demonstrating-results-on-pilco-for-one-dime",totalDownloads:2,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Applied Intelligence - Annual Volume 2022",coverURL:"https://cdn.intechopen.com/books/images_new/11418.jpg",subseries:{id:"22",title:"Applied Intelligence"}}},{id:"81272",title:"Pain Identification in Electroencephalography Signal Using Fuzzy Inference System",doi:"10.5772/intechopen.103753",signatures:"Vahid Asadpour, Reza Fazel-Rezai, Maryam Vatankhah and Mohammad-Reza Akbarzadeh-Totonchi",slug:"pain-identification-in-electroencephalography-signal-using-fuzzy-inference-system",totalDownloads:11,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Brain-Computer Interface",coverURL:"https://cdn.intechopen.com/books/images_new/10654.jpg",subseries:{id:"23",title:"Computational Neuroscience"}}}]},subseriesFiltersForOFChapters:[{caption:"Applied Intelligence",value:22,count:1,group:"subseries"},{caption:"Computer Vision",value:24,count:8,group:"subseries"},{caption:"Machine Learning and Data Mining",value:26,count:8,group:"subseries"},{caption:"Computational Neuroscience",value:23,count:9,group:"subseries"}],publishedBooks:{paginationCount:1,paginationItems:[{type:"book",id:"11392",title:"Leadership in a Changing World",subtitle:"A Multidimensional Perspective",coverURL:"https://cdn.intechopen.com/books/images_new/11392.jpg",slug:"leadership-in-a-changing-world-a-multidimensional-perspective",publishedDate:"May 11th 2022",editedByType:"Edited by",bookSignature:"Muhammad Mohiuddin, Bilal Khalid, Md. Samim Al Azad and Slimane Ed-dafali",hash:"86a6d33cf601587e591064ce92effc02",volumeInSeries:1,fullTitle:"Leadership in a Changing World - A Multidimensional Perspective",editors:[{id:"418514",title:"Dr.",name:"Muhammad",middleName:null,surname:"Mohiuddin",slug:"muhammad-mohiuddin",fullName:"Muhammad Mohiuddin",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000038UqSfQAK/Profile_Picture_2022-05-13T10:39:03.jpg",institutionString:null,institution:{name:"Université Laval",institutionURL:null,country:{name:"Canada"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null}]},subseriesFiltersForPublishedBooks:[{group:"subseries",caption:"Business and Management",value:86,count:1}],publicationYearFilters:[{group:"publicationYear",caption:"2022",value:2022,count:1}],authors:{paginationCount:0,paginationItems:[]}},subseries:{item:{id:"26",type:"subseries",title:"Machine Learning and Data Mining",keywords:"Intelligent Systems, Machine Learning, Data Science, Data Mining, Artificial Intelligence",scope:"The scope of machine learning and data mining is immense and is growing every day. It has become a massive part of our daily lives, making predictions based on experience, making this a fascinating area that solves problems that otherwise would not be possible or easy to solve. This topic aims to encompass algorithms that learn from experience (supervised and unsupervised), improve their performance over time and enable machines to make data-driven decisions. It is not limited to any particular applications, but contributions are encouraged from all disciplines.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/26.jpg",hasOnlineFirst:!0,hasPublishedBooks:!0,annualVolume:11422,editor:{id:"24555",title:"Dr.",name:"Marco Antonio",middleName:null,surname:"Aceves Fernandez",slug:"marco-antonio-aceves-fernandez",fullName:"Marco Antonio Aceves Fernandez",profilePictureURL:"https://mts.intechopen.com/storage/users/24555/images/system/24555.jpg",biography:"Dr. Marco Antonio Aceves Fernandez obtained his B.Sc. (Eng.) in Telematics from the Universidad de Colima, Mexico. He obtained both his M.Sc. and Ph.D. from the University of Liverpool, England, in the field of Intelligent Systems. He is a full professor at the Universidad Autonoma de Queretaro, Mexico, and a member of the National System of Researchers (SNI) since 2009. Dr. Aceves Fernandez has published more than 80 research papers as well as a number of book chapters and congress papers. He has contributed in more than 20 funded research projects, both academic and industrial, in the area of artificial intelligence, ranging from environmental, biomedical, automotive, aviation, consumer, and robotics to other applications. He is also a honorary president at the National Association of Embedded Systems (AMESE), a senior member of the IEEE, and a board member of many institutions. His research interests include intelligent and embedded systems.",institutionString:"Universidad Autonoma de Queretaro",institution:{name:"Autonomous University of Queretaro",institutionURL:null,country:{name:"Mexico"}}},editorTwo:null,editorThree:null,series:{id:"14",title:"Artificial Intelligence",doi:"10.5772/intechopen.79920",issn:"2633-1403"},editorialBoard:[{id:"43680",title:"Prof.",name:"Ciza",middleName:null,surname:"Thomas",slug:"ciza-thomas",fullName:"Ciza Thomas",profilePictureURL:"https://mts.intechopen.com/storage/users/43680/images/system/43680.jpeg",institutionString:null,institution:{name:"Government of Kerala",institutionURL:null,country:{name:"India"}}},{id:"16614",title:"Prof.",name:"Juan Ignacio",middleName:null,surname:"Guerrero Alonso",slug:"juan-ignacio-guerrero-alonso",fullName:"Juan Ignacio Guerrero Alonso",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002g6HB8QAM/Profile_Picture_1627901127555",institutionString:null,institution:{name:"University of Seville",institutionURL:null,country:{name:"Spain"}}},{id:"3095",title:"Prof.",name:"Kenji",middleName:null,surname:"Suzuki",slug:"kenji-suzuki",fullName:"Kenji Suzuki",profilePictureURL:"https://mts.intechopen.com/storage/users/3095/images/1592_n.jpg",institutionString:null,institution:{name:"University of Chicago",institutionURL:null,country:{name:"United States of America"}}},{id:"214067",title:"Dr.",name:"W. David",middleName:null,surname:"Pan",slug:"w.-david-pan",fullName:"W. David Pan",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSEI9QAO/Profile_Picture_1623656213532",institutionString:null,institution:{name:"University of Alabama in Huntsville",institutionURL:null,country:{name:"United States of America"}}},{id:"72920",title:"Prof.",name:"Yves",middleName:"Philippe",surname:"Rybarczyk",slug:"yves-rybarczyk",fullName:"Yves Rybarczyk",profilePictureURL:"https://mts.intechopen.com/storage/users/72920/images/system/72920.jpeg",institutionString:"Dalarna University, Faculty of Data and Information Sciences",institution:{name:"Dalarna University",institutionURL:null,country:{name:"Sweden"}}}]},onlineFirstChapters:{paginationCount:0,paginationItems:[]},publishedBooks:{paginationCount:3,paginationItems:[{type:"book",id:"10859",title:"Data Mining",subtitle:"Concepts and Applications",coverURL:"https://cdn.intechopen.com/books/images_new/10859.jpg",slug:"data-mining-concepts-and-applications",publishedDate:"March 30th 2022",editedByType:"Edited by",bookSignature:"Ciza Thomas",hash:"63a4e514e537d3962cf53ef1c6b9d5eb",volumeInSeries:8,fullTitle:"Data Mining - Concepts and Applications",editors:[{id:"43680",title:"Prof.",name:"Ciza",middleName:null,surname:"Thomas",slug:"ciza-thomas",fullName:"Ciza Thomas",profilePictureURL:"https://mts.intechopen.com/storage/users/43680/images/system/43680.jpeg",institutionString:null,institution:{name:"Government of Kerala",institutionURL:null,country:{name:"India"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"10651",title:"Machine Learning",subtitle:"Algorithms, Models and Applications",coverURL:"https://cdn.intechopen.com/books/images_new/10651.jpg",slug:"machine-learning-algorithms-models-and-applications",publishedDate:"December 22nd 2021",editedByType:"Edited by",bookSignature:"Jaydip Sen",hash:"6208156401c496e0a4ca5ff4265324cc",volumeInSeries:7,fullTitle:"Machine Learning - Algorithms, Models and Applications",editors:[{id:"4519",title:"Prof.",name:"Jaydip",middleName:null,surname:"Sen",slug:"jaydip-sen",fullName:"Jaydip Sen",profilePictureURL:"https://mts.intechopen.com/storage/users/4519/images/system/4519.jpeg",institutionString:"Praxis Business School",institution:null}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"9963",title:"Advances and Applications in Deep Learning",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/9963.jpg",slug:"advances-and-applications-in-deep-learning",publishedDate:"December 9th 2020",editedByType:"Edited by",bookSignature:"Marco Antonio Aceves-Fernandez",hash:"0d51ba46f22e55cb89140f60d86a071e",volumeInSeries:4,fullTitle:"Advances and Applications in Deep Learning",editors:[{id:"24555",title:"Dr.",name:"Marco Antonio",middleName:null,surname:"Aceves Fernandez",slug:"marco-antonio-aceves-fernandez",fullName:"Marco Antonio Aceves Fernandez",profilePictureURL:"https://mts.intechopen.com/storage/users/24555/images/system/24555.jpg",institutionString:"Universidad Autonoma de Queretaro",institution:{name:"Autonomous University of Queretaro",institutionURL:null,country:{name:"Mexico"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null}]},testimonialsList:[{id:"8",text:"I work with IntechOpen for a number of reasons: their professionalism, their mission in support of Open Access publishing, and the quality of their peer-reviewed publications, but also because they believe in equality.",author:{id:"202192",name:"Catrin",surname:"Rutland",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/202192/images/system/202192.png",slug:"catrin-rutland",institution:{id:"134",name:"University of Nottingham",country:{id:null,name:"United Kingdom"}}}},{id:"18",text:"It was great publishing with IntechOpen, the process was straightforward and I had support all along.",author:{id:"71579",name:"Berend",surname:"Olivier",institutionString:"Utrecht University",profilePictureURL:"https://mts.intechopen.com/storage/users/71579/images/system/71579.jpg",slug:"berend-olivier",institution:{id:"253",name:"Utrecht University",country:{id:null,name:"Netherlands"}}}},{id:"27",text:"The opportunity to work with a prestigious publisher allows for the possibility to collaborate with more research groups interested in animal nutrition, leading to the development of new feeding strategies and food valuation while being more sustainable with the environment, allowing more readers to learn about the subject.",author:{id:"175967",name:"Manuel",surname:"Gonzalez Ronquillo",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/175967/images/system/175967.png",slug:"manuel-gonzalez-ronquillo",institution:{id:"6221",name:"Universidad Autónoma del Estado de México",country:{id:null,name:"Mexico"}}}}]},submityourwork:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:8,numberOfPublishedChapters:86,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:96,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:27,numberOfPublishedChapters:283,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:9,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:11,numberOfPublishedChapters:138,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:8,numberOfPublishedChapters:128,numberOfOpenTopics:0,numberOfUpcomingTopics:2,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!1},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:105,numberOfOpenTopics:3,numberOfUpcomingTopics:1,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:9,numberOfPublishedChapters:100,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:11,numberOfOpenTopics:2,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:0,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!1},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:0,numberOfPublishedChapters:9,numberOfOpenTopics:4,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],subseriesList:[{id:"22",title:"Applied Intelligence",scope:"This field is the key in the current industrial revolution (Industry 4.0), where the new models and developments are based on the knowledge generation on applied intelligence. The motor of the society is the industry and the research of this topic has to be empowered in order to increase and improve the quality of our lives.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/22.jpg",keywords:"Machine Learning, Intelligence Algorithms, Data Science, Artificial Intelligence, Applications on Applied Intelligence"},{id:"23",title:"Computational Neuroscience",scope:"Computational neuroscience focuses on biologically realistic abstractions and models validated and solved through computational simulations to understand principles for the development, structure, physiology, and ability of the nervous system. This topic is dedicated to biologically plausible descriptions and computational models - at various abstraction levels - of neurons and neural systems. This includes, but is not limited to: single-neuron modeling, sensory processing, motor control, memory, and synaptic plasticity, attention, identification, categorization, discrimination, learning, development, axonal patterning, guidance, neural architecture, behaviors, and dynamics of networks, cognition and the neuroscientific basis of consciousness. Particularly interesting are models of various types of more compound functions and abilities, various and more general fundamental principles (e.g., regarding architecture, organization, learning, development, etc.) found at various spatial and temporal levels.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/23.jpg",keywords:"Single-Neuron Modeling, Sensory Processing, Motor Control, Memory and Synaptic Pasticity, Attention, Identification, Categorization, Discrimination, Learning, Development, Axonal Patterning and Guidance, Neural Architecture, Behaviours and Dynamics of Networks, Cognition and the Neuroscientific Basis of Consciousness"},{id:"24",title:"Computer Vision",scope:"The scope of this topic is to disseminate the recent advances in the rapidly growing field of computer vision from both the theoretical and practical points of view. Novel computational algorithms for image analysis, scene understanding, biometrics, deep learning and their software or hardware implementations for natural and medical images, robotics, VR/AR, applications are some research directions relevant to this topic.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/24.jpg",keywords:"Image Analysis, Scene Understanding, Biometrics, Deep Learning, Software Implementation, Hardware Implementation, Natural Images, Medical Images, Robotics, VR/AR"},{id:"25",title:"Evolutionary Computation",scope:"Evolutionary computing is a paradigm that has grown dramatically in recent years. This group of bio-inspired metaheuristics solves multiple optimization problems by applying the metaphor of natural selection. It so far has solved problems such as resource allocation, routing, schedule planning, and engineering design. Moreover, in the field of machine learning, evolutionary computation has carved out a significant niche both in the generation of learning models and in the automatic design and optimization of hyperparameters in deep learning models. This collection aims to include quality volumes on various topics related to evolutionary algorithms and, alternatively, other metaheuristics of interest inspired by nature. For example, some of the issues of interest could be the following: Advances in evolutionary computation (Genetic algorithms, Genetic programming, Bio-inspired metaheuristics, Hybrid metaheuristics, Parallel ECs); Applications of evolutionary algorithms (Machine learning and Data Mining with EAs, Search-Based Software Engineering, Scheduling, and Planning Applications, Smart Transport Applications, Applications to Games, Image Analysis, Signal Processing and Pattern Recognition, Applications to Sustainability).",coverUrl:"https://cdn.intechopen.com/series_topics/covers/25.jpg",keywords:"Genetic Algorithms, Genetic Programming, Evolutionary Programming, Evolution Strategies, Hybrid Algorithms, Bioinspired Metaheuristics, Ant Colony Optimization, Evolutionary Learning, Hyperparameter Optimization"},{id:"26",title:"Machine Learning and Data Mining",scope:"The scope of machine learning and data mining is immense and is growing every day. It has become a massive part of our daily lives, making predictions based on experience, making this a fascinating area that solves problems that otherwise would not be possible or easy to solve. This topic aims to encompass algorithms that learn from experience (supervised and unsupervised), improve their performance over time and enable machines to make data-driven decisions. It is not limited to any particular applications, but contributions are encouraged from all disciplines.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/26.jpg",keywords:"Intelligent Systems, Machine Learning, Data Science, Data Mining, Artificial Intelligence"},{id:"27",title:"Multi-Agent Systems",scope:"Multi-agent systems are recognised as a state of the art field in Artificial Intelligence studies, which is popular due to the usefulness in facilitation capabilities to handle real-world problem-solving in a distributed fashion. The area covers many techniques that offer solutions to emerging problems in robotics and enterprise-level software systems. Collaborative intelligence is highly and effectively achieved with multi-agent systems. Areas of application include swarms of robots, flocks of UAVs, collaborative software management. Given the level of technological enhancements, the popularity of machine learning in use has opened a new chapter in multi-agent studies alongside the practical challenges and long-lasting collaboration issues in the field. It has increased the urgency and the need for further studies in this field. We welcome chapters presenting research on the many applications of multi-agent studies including, but not limited to, the following key areas: machine learning for multi-agent systems; modeling swarms robots and flocks of UAVs with multi-agent systems; decision science and multi-agent systems; software engineering for and with multi-agent systems; tools and technologies of multi-agent systems.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/27.jpg",keywords:"Collaborative Intelligence, Learning, Distributed Control System, Swarm Robotics, Decision Science, Software Engineering"}],annualVolumeBook:{},thematicCollection:[],selectedSeries:{title:"Artificial Intelligence",id:"14"},selectedSubseries:null},seriesLanding:{item:{id:"7",title:"Biomedical Engineering",doi:"10.5772/intechopen.71985",issn:"2631-5343",scope:"Biomedical Engineering is one of the fastest-growing interdisciplinary branches of science and industry. The combination of electronics and computer science with biology and medicine has improved patient diagnosis, reduced rehabilitation time, and helped to facilitate a better quality of life. Nowadays, all medical imaging devices, medical instruments, or new laboratory techniques result from the cooperation of specialists in various fields. The series of Biomedical Engineering books covers such areas of knowledge as chemistry, physics, electronics, medicine, and biology. This series is intended for doctors, engineers, and scientists involved in biomedical engineering or those wanting to start working in this field.",coverUrl:"https://cdn.intechopen.com/series/covers/7.jpg",latestPublicationDate:"May 7th, 2022",hasOnlineFirst:!0,numberOfOpenTopics:3,numberOfPublishedChapters:96,numberOfPublishedBooks:12,editor:{id:"50150",title:"Prof.",name:"Robert",middleName:null,surname:"Koprowski",fullName:"Robert Koprowski",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYTYNQA4/Profile_Picture_1630478535317",biography:"Robert Koprowski, MD (1997), PhD (2003), Habilitation (2015), is an employee of the University of Silesia, Poland, Institute of Computer Science, Department of Biomedical Computer Systems. For 20 years, he has studied the analysis and processing of biomedical images, emphasizing the full automation of measurement for a large inter-individual variability of patients. Dr. Koprowski has authored more than a hundred research papers with dozens in impact factor (IF) journals and has authored or co-authored six books. Additionally, he is the author of several national and international patents in the field of biomedical devices and imaging. Since 2011, he has been a reviewer of grants and projects (including EU projects) in biomedical engineering.",institutionString:null,institution:{name:"University of Silesia",institutionURL:null,country:{name:"Poland"}}},subseries:[{id:"7",title:"Bioinformatics and Medical Informatics",keywords:"Biomedical Data, Drug Discovery, Clinical Diagnostics, Decoding Human Genome, AI in Personalized Medicine, Disease-prevention Strategies, Big Data Analysis in Medicine",scope:"Bioinformatics aims to help understand the functioning of the mechanisms of living organisms through the construction and use of quantitative tools. The applications of this research cover many related fields, such as biotechnology and medicine, where, for example, Bioinformatics contributes to faster drug design, DNA analysis in forensics, and DNA sequence analysis in the field of personalized medicine. Personalized medicine is a type of medical care in which treatment is customized individually for each patient. Personalized medicine enables more effective therapy, reduces the costs of therapy and clinical trials, and also minimizes the risk of side effects. Nevertheless, advances in personalized medicine would not have been possible without bioinformatics, which can analyze the human genome and other vast amounts of biomedical data, especially in genetics. The rapid growth of information technology enabled the development of new tools to decode human genomes, large-scale studies of genetic variations and medical informatics. The considerable development of technology, including the computing power of computers, is also conducive to the development of bioinformatics, including personalized medicine. In an era of rapidly growing data volumes and ever lower costs of generating, storing and computing data, personalized medicine holds great promises. Modern computational methods used as bioinformatics tools can integrate multi-scale, multi-modal and longitudinal patient data to create even more effective and safer therapy and disease prevention methods. Main aspects of the topic are: Applying bioinformatics in drug discovery and development; Bioinformatics in clinical diagnostics (genetic variants that act as markers for a condition or a disease); Blockchain and Artificial Intelligence/Machine Learning in personalized medicine; Customize disease-prevention strategies in personalized medicine; Big data analysis in personalized medicine; Translating stratification algorithms into clinical practice of personalized medicine.",annualVolume:11403,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/7.jpg",editor:{id:"351533",title:"Dr.",name:"Slawomir",middleName:null,surname:"Wilczynski",fullName:"Slawomir Wilczynski",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000035U1loQAC/Profile_Picture_1630074514792",institutionString:null,institution:{name:"Medical University of Silesia",institutionURL:null,country:{name:"Poland"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"5886",title:"Dr.",name:"Alexandros",middleName:"T.",surname:"Tzallas",fullName:"Alexandros Tzallas",profilePictureURL:"https://mts.intechopen.com/storage/users/5886/images/system/5886.png",institutionString:"University of Ioannina, Greece & Imperial College London",institution:{name:"University of Ioannina",institutionURL:null,country:{name:"Greece"}}},{id:"257388",title:"Distinguished Prof.",name:"Lulu",middleName:null,surname:"Wang",fullName:"Lulu Wang",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRX6kQAG/Profile_Picture_1630329584194",institutionString:null,institution:{name:"Shenzhen Technology University",institutionURL:null,country:{name:"China"}}},{id:"225387",title:"Prof.",name:"Reda",middleName:"R.",surname:"Gharieb",fullName:"Reda Gharieb",profilePictureURL:"https://mts.intechopen.com/storage/users/225387/images/system/225387.jpg",institutionString:"Assiut University",institution:{name:"Assiut University",institutionURL:null,country:{name:"Egypt"}}}]},{id:"8",title:"Bioinspired Technology and Biomechanics",keywords:"Bioinspired Systems, Biomechanics, Assistive Technology, Rehabilitation",scope:'Bioinspired technologies take advantage of understanding the actual biological system to provide solutions to problems in several areas. Recently, bioinspired systems have been successfully employing biomechanics to develop and improve assistive technology and rehabilitation devices. The research topic "Bioinspired Technology and Biomechanics" welcomes studies reporting recent advances in bioinspired technologies that contribute to individuals\' health, inclusion, and rehabilitation. Possible contributions can address (but are not limited to) the following research topics: Bioinspired design and control of exoskeletons, orthoses, and prostheses; Experimental evaluation of the effect of assistive devices (e.g., influence on gait, balance, and neuromuscular system); Bioinspired technologies for rehabilitation, including clinical studies reporting evaluations; Application of neuromuscular and biomechanical models to the development of bioinspired technology.',annualVolume:11404,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/8.jpg",editor:{id:"144937",title:"Prof.",name:"Adriano",middleName:"De Oliveira",surname:"Andrade",fullName:"Adriano Andrade",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRC8QQAW/Profile_Picture_1625219101815",institutionString:null,institution:{name:"Federal University of Uberlândia",institutionURL:null,country:{name:"Brazil"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"49517",title:"Prof.",name:"Hitoshi",middleName:null,surname:"Tsunashima",fullName:"Hitoshi Tsunashima",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYTP4QAO/Profile_Picture_1625819726528",institutionString:null,institution:{name:"Nihon University",institutionURL:null,country:{name:"Japan"}}},{id:"425354",title:"Dr.",name:"Marcus",middleName:"Fraga",surname:"Vieira",fullName:"Marcus Vieira",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00003BJSgIQAX/Profile_Picture_1627904687309",institutionString:null,institution:{name:"Universidade Federal de Goiás",institutionURL:null,country:{name:"Brazil"}}},{id:"196746",title:"Dr.",name:"Ramana",middleName:null,surname:"Vinjamuri",fullName:"Ramana Vinjamuri",profilePictureURL:"https://mts.intechopen.com/storage/users/196746/images/system/196746.jpeg",institutionString:"University of Maryland, Baltimore County",institution:{name:"University of Maryland, Baltimore County",institutionURL:null,country:{name:"United States of America"}}}]},{id:"9",title:"Biotechnology - Biosensors, Biomaterials and Tissue Engineering",keywords:"Biotechnology, Biosensors, Biomaterials, Tissue Engineering",scope:"The Biotechnology - Biosensors, Biomaterials and Tissue Engineering topic within the Biomedical Engineering Series aims to rapidly publish contributions on all aspects of biotechnology, biosensors, biomaterial and tissue engineering. We encourage the submission of manuscripts that provide novel and mechanistic insights that report significant advances in the fields. Topics can include but are not limited to: Biotechnology such as biotechnological products and process engineering; Biotechnologically relevant enzymes and proteins; Bioenergy and biofuels; Applied genetics and molecular biotechnology; Genomics, transcriptomics, proteomics; Applied microbial and cell physiology; Environmental biotechnology; Methods and protocols. Moreover, topics in biosensor technology, like sensors that incorporate enzymes, antibodies, nucleic acids, whole cells, tissues and organelles, and other biological or biologically inspired components will be considered, and topics exploring transducers, including those based on electrochemical and optical piezoelectric, thermal, magnetic, and micromechanical elements. Chapters exploring biomaterial approaches such as polymer synthesis and characterization, drug and gene vector design, biocompatibility, immunology and toxicology, and self-assembly at the nanoscale, are welcome. Finally, the tissue engineering subcategory will support topics such as the fundamentals of stem cells and progenitor cells and their proliferation, differentiation, bioreactors for three-dimensional culture and studies of phenotypic changes, stem and progenitor cells, both short and long term, ex vivo and in vivo implantation both in preclinical models and also in clinical trials.",annualVolume:11405,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/9.jpg",editor:{id:"126286",title:"Dr.",name:"Luis",middleName:"Jesús",surname:"Villarreal-Gómez",fullName:"Luis Villarreal-Gómez",profilePictureURL:"https://mts.intechopen.com/storage/users/126286/images/system/126286.jpg",institutionString:null,institution:{name:"Autonomous University of Baja California",institutionURL:null,country:{name:"Mexico"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"35539",title:"Dr.",name:"Cecilia",middleName:null,surname:"Cristea",fullName:"Cecilia Cristea",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYQ65QAG/Profile_Picture_1621007741527",institutionString:null,institution:{name:"Iuliu Hațieganu University of Medicine and Pharmacy",institutionURL:null,country:{name:"Romania"}}},{id:"40735",title:"Dr.",name:"Gil",middleName:"Alberto Batista",surname:"Gonçalves",fullName:"Gil Gonçalves",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYRLGQA4/Profile_Picture_1628492612759",institutionString:null,institution:{name:"University of Aveiro",institutionURL:null,country:{name:"Portugal"}}},{id:"211725",title:"Associate Prof.",name:"Johann F.",middleName:null,surname:"Osma",fullName:"Johann F. Osma",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSDv7QAG/Profile_Picture_1626602531691",institutionString:null,institution:{name:"Universidad de Los Andes",institutionURL:null,country:{name:"Colombia"}}},{id:"69697",title:"Dr.",name:"Mani T.",middleName:null,surname:"Valarmathi",fullName:"Mani T. Valarmathi",profilePictureURL:"https://mts.intechopen.com/storage/users/69697/images/system/69697.jpg",institutionString:"Religen Inc. | A Life Science Company, United States of America",institution:null},{id:"205081",title:"Dr.",name:"Marco",middleName:"Vinícius",surname:"Chaud",fullName:"Marco Chaud",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSDGeQAO/Profile_Picture_1622624307737",institutionString:null,institution:{name:"Universidade de Sorocaba",institutionURL:null,country:{name:"Brazil"}}}]}]}},libraryRecommendation:{success:null,errors:{},institutions:[]},route:{name:"onlineFirst.detail",path:"/online-first/81222",hash:"",query:{},params:{id:"81222"},fullPath:"/online-first/81222",meta:{},from:{name:null,path:"/",hash:"",query:{},params:{},fullPath:"/",meta:{}}}},function(){var e;(e=document.currentScript||document.scripts[document.scripts.length-1]).parentNode.removeChild(e)}()