Decision-Making for ALL Reconstruction and Surgical Techniques

The anterolateral ligament (ALL), which was first described in 1879, was reintroduced in 2013 by Claes et al. It originates near the lateral epicondyle of the distal femur, runs along the lateral outer aspect of the knee, and inserts on the proximal tibia between Gerdy’s tubercle and fibular head. The ALL tightens when the knee is internally rotated (twisted inwards), and in doing so, it is proposed to be a stabilizer to internal tibial rotation. Biomechanical studies showed that the ALL restrains internal rotation of the tibia and thus affects the pivot-shift phenomenon in the anterior cruciate ligament (ACL)-injured knee. Therefore, it is proposed that the deficient ALL can be a reason for persistent rotatory instability after ACL reconstruction. Furthermore, ALL reconstruction techniques have evolved and indications extended. Commonly accepted indications for concomitant ACL and ALL reconstruction are ACL revisions, high-grade pivot-shift test, chronic ACL rupture, and young patients and patients doing pivoting activities. Most surgeons perform an anatomic reconstruction technique with gracilis autograft. However, only few studies published reporting the outcomes of ALL reconstruction and more studies with longer follow-up times are, therefore, needed to provide the compelling clinical evidence for the efficacy of concomitant ACL and ALL procedures.


Introduction
The anterolateral ligament (ALL) is a newly re-introduced ligament on the lateral aspect of the knee, which originates at the lateral epicondyle of the femur, and inserts at the anterolateral aspect of the proximal tibia. It was first described by Paul Segond as "a pearly, resistant, fibrous band" at the anterolateral aspect of the human knee; however, it was not given much importance until Claes et al. identified the ALL in an anatomic study as a distinct structure of the lateral compartment of the knee [1]. Subsequently, many studies have been published regarding the anatomy, biomechanics, and radiology of ALL.
The clinical relevance of ALL mostly comes from its high association with anterior cruciate ligament (ACL) injuries. Studies showed a high incidence of radiological ALL damage (78.7%) in ACL-injured knees [2]. Biomechanically, it is claimed to be a stabilizer in internal rotation of the tibia particularly at high knee flexion Decision-Making for ALL Reconstruction and Surgical Techniques DOI: http://dx.doi.org /10.5772/intechopen.86398 strength of 175 N (139-211 N 95% CI) and stiffness 20 N/mm [12][13][14][15][16][17][18][19][20][21] with a more substantial structure than that shown by Zens et al. [10]. The mean ultimate load to failure and the mean stiffness of ALL have been measured between 50 and 205 N and between 20 and 42 N/mm, respectively, in different studies [11,22,23].
In most of the studies, the ALL is described as a secondary stabilizer to internal rotation and to some extent anterior translation [3,24,25]. The biomechanical studies demonstrated that in the presence of ACL deficiency, sectioning the ALL in cadaveric specimens significantly effects the anteroposterior (AP) stability as well as results in a significant increase in internal rotation [12,24]. The contribution of the ALL during internal rotation increases significantly with increasing flexion, whereas that of the ACL decreased significantly. Therefore, it is speculated that the ALL deficiency can be a reason for persistent rotational instability after ACL reconstruction [13].
The isometry of the ALL was measured by Dodds et al. [7], by threading a suture along the ligament fibers, attaching it to the moving tibia and then measuring the changes of the separation distance between the attachments using a transducer. It was shown that the ALL was not isometric, but was close to being isometric from 0 to 60° knee flexion. Internal tibial rotation increased the length between the attachments, and external rotation reduced it. When the knee was in extension, tibial rotations in response to 5 Nm torque were not large enough to cause significant change in the length of the ALL. However, internal tibial rotation increased the mean length between the ALL attachments from 3.6 mm (SD 0.7; 1.5-5.7) at 30° (p = 0.003) to 9.9 mm (SD 1.4; 5.7-14.2) at 90° of flexion of the knee. Imbert et al. [14] investigated isometric characteristics of the ALL in a cadaveric navigation study and found that ALL is not isometric at any of the femoral insertion locations but had different length change patterns during knee flexion and internal tibial rotation at 90°. However, they found that the proximal and posterior to epicondyle femoral position is favorable to being isometry.

Injury
Injury to the ALL is most commonly associated with a concomitant tear of the ACL. In a retrospective MRI study, Claes et al. [2] analyzed 206 ACL injured knees and found 78.8% radiological ALL abnormalities. Most of the ALL abnormalities were found to be situated in the distal part of the ligament (77.8%), whereas 20.4% of the injuries were proximal and only 1.8% knees were diagnosed with a bony ALL avulsion. Ferretti et al. [15] exposed the lateral knee compartments of 60 patients undergoing ACLR and found several lesion types of the ALL injuries including macroscopic hemorrhage extending to the anterolateral capsule (32%) or to the posterolateral capsule (27%), complete transverse tear of the ALL near its tibial insertion (22%), and a bony tibial avulsion (Segond fracture) (10%). In a retrospective MRI study, Gurpinar et al. found 65.2% ALL injury in patients underwent ACL surgery who were diagnosed with isolated ACL injury previously [13]. In a similar study, van Dyck et al. [16] found ALL abnormalities in 46% of 90 knee MRIs of patients with an acute ACL rupture. Furthermore, they found that these patients were more likely to have a lateral meniscal tear, collateral ligament injury, or osseous injury compared with patients with an intact ALL.
After re-discovery of ALL, Segond fractures, which were previously considered as a diagnostic clue for ACL injury, are classified as ALL equivalent injuries [17]. Porrino et al. [18] evaluated 20 knee MRIs with a Segond fracture and found that the ALL was attached to the fracture fragment in all but one case limited by anatomic distortion. Claes et al. [17] also suggested that the Segond fracture is actually Knee Surgery -Reconstruction and Replacement a bony avulsion of the ALL. However, Shaikh et al. [19] claimed that ITB and lateral capsule attached to the Segond fracture in 94% of the patients and Segond fracture is not merely an ALL avulsion but the avulsion of the anterolateral complex.
On the other hand, anterolateral injuries and instability can also occur in the ACL intact states. Gottsegen et al. [20] and DeLee et al. [21] reported the Segond fracture combined to popliteal tendon avulsion and iliotibial band avulsion. Wharton et al. [26] published a case report in which the Segond fracture was combined to posterolateral ligament injury without ACL rupture. Furthermore, Ferreira reported an absolute isolated Segond fracture.

Diagnosis
Diagnosing ALL lesions can be difficult since no specific clinical tests have been validated for the diagnosis of ALL injuries. To achieve an impeccable diagnosis, meticulous clinical examination and appropriate evaluation of the radiographic and MRI imaging are necessary. Since ALL is highly associated with ACL injury, patients subjected to trauma mechanisms similar to an isolated ACL injury such as contact and noncontact injuries involving early flexion, dynamic valgus, and internal rotation should also be suspected for ALL injury. Anterior drawer and Lachman tests can be positive due to the concomitant ACL injury. However, since ALL is primarily responsible for rotational stability, pivot-shift test is considered to be the most reliable test to evaluate ALL integrity. Monaco et al. [27] demonstrated that a grade III pivot shift is only seen in the absence of both the ACL and ALL in vitro. However, the potential confusing factors of a high-grade pivot shift, such as a lateral meniscus or root tear, ITB injury, or general hyperlaxity should be assessed [28,29].
Segond fracture is also considered to be ALL avulsion, and therefore, it can be assumed that symptoms related to a Segond fracture may be present in ALL injury including provoked pain on palpation of the lateral tibia or increased laxity in varus stress. On examination, the lateral compartment of the knee should be carefully evaluated, and the integrity of the cruciate and collateral ligaments should be examined too. However, in the acute phase, diagnosis can be challenging and evaluation should be repeated in subacute and chronic phases after swelling and pain has decreased.

Surgical indications
The optimal ACL reconstruction is still a debate in orthopedic research, and persistent rotatory instability has been reported up to 25% of cases after an isolated ACL reconstruction procedure [30]. Some studies found that an isolated ACL reconstruction can control the translational instability, but is insufficient to restore the normal rotational stability. In addition, the persistent rotatory instability does not only cause difficulties with pivoting sports, but also can cause secondary meniscal and cartilaginous problems [31]. Furthermore, younger and higher-level athletes with rotational instability can be vulnerable to re-ruptures. Therefore, combining a lateral extra-articular procedure with an intra-articular reconstruction for the treatment of ACL injury emerged, with the aim of decreasing rotational instability. However, long-term results of ALL reconstruction are not known and have not been suggested as a standard procedure with ACL reconstruction. Despite this, additional ALL reconstruction has been recommended in patients with grade III pivot shift or Segond fracture and athletes practicing of sports with pivot movements [32][33][34]. In addition ACL revision, subjective rotational looseness, and Telos value >10 mm are also considered as indicative of ALL reconstruction associated with ACL reconstruction [35]. Some surgeons also suggested ALL reconstruction in cases of chronic ACL reconstruction, high level of sports activity, and radiographic lateral femoral notch sign [36].
Recently the ALL Expert Group [37] proposed a decision tree for the management of ACL ruptures and recommended ALL reconstruction for patients who present at least: (1) decisive criteria for increased risk of secondary ACL rupture or postoperative residual positive pivot shift or (2) secondary criteria for increased risk of secondary ACL rupture or postoperative residual positive pivot shift including history, clinical or imaging signs, or patient profile. However, literature still lacks good-quality randomized studies and more studies are needed to prove these findings.

Graft type and preparation
Wytrykowski et al. [38] performed a cadaveric study to compare the biomechanical properties of the ALL, gracilis, and IT band. The gracilis was found to have six times the stiffness of the ALL (131.7 vs. 21 N/mm) and had the highest maximum load to failure (200.7 vs. 141 N). The mechanical properties of the IT band (stiffness, 39.9 N/mm; maximum load to failure, 161.1 N) most closely resembled those of the ALL. However, many authors have published techniques using a gracilis graft for ALL reconstruction and a tripled semitendinosus auto-or allograft or quadrupled semitendinosus autograft with all-inside technique for the reconstruction of ACL [39][40][41]. The use of polyester tape [42] or a single-bundle semitendinosus auto-or allograft has also been described in the literature [43]. In our clinic, we use gracilis graft for ALL reconstruction, and for the ACL, we use quadriceps autograft, tripled semitendinosus, or allograft.

Femoral and tibial origins and fixation
On the tibia, the anatomical landmarks are the center of the fibula head, the center of Gerdy's tubercle, and joint line (Figure 2a). We use the midpoint between Gerdy's tubercle and the fibula at 5-10 mm below the lateral joint line for the site of tibial fixation. We make a stab incision 5-10 mm below the joint line, halfway between the center of Gerdy's tubercle and the fibula head (Figure 2b). Helito et al. [44] have described the radiographic landmarks to determine this location. They choose a point around 7 mm below the tibial plateau on the AP view and around 50% of the plateau length on the lateral view [39]. Similar tibial attachment points have been used by many authors; however, some surgeons used two attachment points, and therefore, they used one point just anterior to the fibular head and second point posterior to the Gerdy's tubercle [45].
Since the origin of the femoral insertion of the ALL varies, the location of femoral fixation during ALLR is a debate. Many authors [40,46,47] described a fixation at a point posterior and superior to the lateral femoral epicondyle; however, some [41,42] [11]. In our clinic, we make a 5-10 mm incision just proximal to the epicondyle, and after dividing the ITB, we insert the drill pin slightly proximal and posterior to the lateral epicondyle (Figure 1c and d).
After inserting femoral and tibial pin guides, the passing suture is placed under the ITB around the femoral wire and tibial wires. The knee is then moved through the full range of motion (Figure 1d). The isometry assessment is made to be sure that the graft will not tighten in flexion and will be tight in extension. If the suture tightens in flexion, the femoral socket may be too distal or anterior.
After the isometry test, the graft is passed under the ITB and fixed with interference screws or anchors on both sides, while the knee is 30° flexed and at neutral rotation (Figure 2). However, fixation in full extension at 45-60° of flexion or fixation at 60-90° of flexion have also been described in the literature [39,40,47]. Different surgical techniques and indications are summarized in Table 1.

Postoperative rehabilitation
The plaster cast immobilization or bracing were popular in the historical literature when ACL and lateral extra-articular procedures were performed together [49]. However, use of brace is much less common in current practice. Many authors recommend that rehabilitation after an additional ALL reconstruction should be carried out in a similar way compared to isolated ACL rehabilitation. An early aggressive rehabilitation program can be applied. Emphasis should be placed on achieving symmetrical full knee extension, decreasing knee joint effusion, and quadriceps activation early in the rehabilitation process. Passive flexion and patellar mobilization, avoiding eccentric quadriceps contraction, should also be performed. Weight bearing as tolerated is recommended immediately following surgery to promote knee extension and hinder quadriceps inhibition. Step-by-step anterolateral ligament reconstruction.

Clinical outcomes
To date, only few studies reported the clinical outcomes of ALL reconstruction since the rediscovery of this ligament [32,33,36,50]. In a retrospective case series, Sonnery-Cottet et al. [36] evaluated 92 patients at a minimum 2-year follow-up after concomitant ACL and ALL reconstruction. Compared with the preoperative assessment, the follow-up showed significant improvements in Lysholm score, subjective IKDC score, and objective IKDC score. Pivot-shift results were also significantly improved; however, this study did not have a control group.
In a prospective comparative study of 502 patients, Sonnery et al. found lower graft rupture rate with combined ALL-ACL reconstruction technique in a high-risk population, compared to the isolated ACL reconstructions that used a bone-patellar tendon-bone graft or a quadrupled hamstring tendon graft [33]. Another randomized study showed an improvement in knee laxity measured using a KT-1000 arthrometer in patients with combined ACL and ALL reconstructions compared to patients with isolated ACL reconstructions; however, the other measured parameters did not differ significantly [32]. Recently, Helito et al. [50] evaluated the results of combined ACL-ALL reconstruction with isolated ACL reconstruction in 101 chronic ACL injuries. Regarding functional outcome scores, they found better results on both the IKDC and the Lysholm evaluations in combined ACL-ALL reconstruction group. In addition, patients in the ACL-ALL reconstruction group had better KT-1000 evaluation and a lower pivot-shift rate at physical examination. Although the results of the recent studies are promising, indications for ALL reconstruction are not identical in these studies and additional studies are needed to confirm these results.

Conclusions
In conclusion, it is commonly accepted that the ALL is a distinctive structure that originates from proximal and posterior to the femoral epicondyle, attaches slightly posterior to the Gerdy's tubercle, and functions as a secondary stabilizer to internal rotation. In addition, it has been reported that it has a crucial role in preventing pivot-shift phenomenon. However, there is a lack of evidence supporting that it can be a reason for persistent pivot shift after ACL reconstructions [13]. Although the results of the recent studies reporting the outcomes of ALL reconstruction are promising, the total volume of literature on this topic is limited and composed of low-quality evidence. More studies with longer follow-up times are, therefore, needed to provide the convincing clinical evidence for the favor of concomitant ACL and ALL procedures. In addition, despite the lack of clear evidence for an increase in lateral compartment osteoarthritis after concomitant procedures, compression in the lateral compartment seems to be a concern and was regarded as a reason to abandon concomitant lateral procedures historically [51-53].
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Author details
Tahsin Gurpinar University of Health Sciences, Istanbul Research and Education Hospital, Istanbul, Turkey *Address all correspondence to: tahsingurpinar@msn.com