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# Laser-Driven Proton Acceleration Research and Development

Written By

Alexander S. Pirozhkov, Hiroyuki Daido, Mamiko Nishiuchi and Koichi Ogura

Published: February 1st, 2010

DOI: 10.5772/7967

From the Edited Volume

## Advances in Solid State Lasers

Edited by Mikhail Grishin

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## 1. Introduction

Up to now the acceleration of charged particles in most cases is based on the radio-frequency based technology. Another approach is to employ ultrahigh collective fields of plasmas produced by high-power lasers. Using various schemes, these plasma fields can be used to accelerate electrons, protons, and heavier ions. Laser-driven ion beams exhibit unique properties, among which are short duration, small source size, large number of particles, low emittance, etc. The laser-driven acceleration is inherently a very compact process, because the acceleration typically takes place within a micrometer spatial and picosecond time scales; the acceleration field can exceed TV/m, which allows achieving multi-MeV/nucleon ion energies. For the detailed reviews, see (Borghesi et al. 2006; Mourou et al. 2006) and references therein. The peculiar properties of the laser-driven proton beam, namely short duration, low emittance, and large particle number have been used in the proton imaging, which allows measurement of transient field distribution in plasma experiments (Borghesi et al. 2001); the broad proton energy spectrum allows multi-frame time-resolved studies in single shot. A compact laser-based laboratory setup has been used for the proof-of-principle radiological experiment (Yogo et al. 2009), which can be applicable in the biological, medical, and space research (Murakami et al. 2009). There are many other attractive potential applications of the laser-driven ion beams, among which the hadron therapy (Bulanov et al. 2002; Bulanov & Khoroshkov 2002), fast ignition (Roth et al. 2001), injectors into conventional accelerators (Krushelnick et al. 2000; Cowan et al. 2004), material processing, isotope production (Nemoto et al. 2001; Fritzler et al. 2003), pion production (Bychenkov et al. 2001), pump-probe experiments using simultaneous production of proton beam and THz radiation (Sagisaka et al. 2008), x-rays (Orimo et al. 2007), electrons (Li et al. 2006), and so on.

For many applications, the parameters of the presently available laser-driven ion beams need to be improved. In particular, it is necessary to increase the maximum ion energy, simultaneously achieving high conversion efficiency. At present, this is an active area of research. Up to now a substantial part of results has been obtained with relatively large-scale, single-shot picosecond and sub-picosecond laser systems (Hatchett et al. 2000; Snavely et al. 2000; Fuchs et al. 2006; Robson et al. 2007; Henig et al. 2009). However, for many applications a compact, repetitive ion source is necessary. For such applications, it is attractive to use high-power femtosecond lasers, which have smaller pulse energies at the same power levels, and therefore can provide higher repetition rates. In this Chapter we present the results of proton acceleration and plasma diagnostic experiments (Pirozhkov et al. 2009c) conducted with a repetitive femtosecond J-KAREN laser at the Advanced Photon Research Center, Japan Atomic Energy Agency. In Sections 2 and 3 we describe the laser parameters and the results of the experiments and discuss the influence of several parameters on the maximum proton energy; we show the strong influence of the laser contrast on the proton acceleration process. In Section 4 we analyze the results of the on-target laser contrast measurement, which has been performed at full laser power using the properties of radiation reflected from the target. In Section 5 we describe the laser-driven proton beam manipulation using permanent magnet quadrupoles. In Section 6 we describe the radioactivation experiments using multi-MeV laser-driven proton source.

## 2. Lasers for proton acceleration: present status and future prospects

### 2.1. High-power picosecond and femtosecond lasers

Up to now, the highest proton energies, the largest proton numbers and conversion efficiencies have been obtained using high-energy ps and sub-ps lasers. The proton energies close to 60 MeV (Hatchett et al. 2000; Snavely et al. 2000; Robson et al. 2007) have been achieved using petawatt lasers based on the Chirped Pulse Amplification (CPA) technology (Strickland & Mourou 1985). In these experiments, thin foil targets were irradiated by the focused laser pulses with intensities exceeding 1020 W/cm2; regardless of the target material, the accelerated ions were predominantly protons originating from the water or hydrocarbon surface contamination. If the contamination was removed e.g. by joule or laser heating, heavier ions had been accelerated (Hegelich et al. 2002; McKenna et al. 2004). The acceleration has been attributed to the process known as Target Normal Sheath Acceleration (TNSA) (Hatchett et al. 2000; Mora 2003).

The experiments in which multi-10 MeV/nucleon protons and ions were accelerated within very short acceleration distances have caused great interest to the field of laser-driven ion acceleration. One of the attractive directions of research is miniaturization of the accelerator employing compact, relatively high-repetition rate CPA lasers with even shorter (femtosecond) pulse durations; the compactness and higher repetition rate can be achieved in this case because of the smaller pulse energy required to provide similar peak power and intensity. However, at present the achievable proton energies in this case are lower. Despite this, a number of application and proof-of-principle experiments have been performed with the ion and proton beams driven by compact femtosecond lasers. Ion energies up to 10-20 MeV/nucleon (Fukuda et al. 2009) and the laser-to-proton beam conversion efficiencies up to 3% (proton energy > 0.8 MeV) (Nishiuchi et al. 2008) have been demonstrated.

### 2.2. J-KAREN laser

The experiments described in this Chapter (Pirozhkov et al. 2009c) have been conducted using hybrid OPCPA/Ti:Sapphire J-KAREN laser (Kiriyama et al. 2008; Kiriyama et al. 2009); here OPCPA stands for the Optical Parametric Chirped Pulse Amplification. The laser consists of a CPA oscillator with high pulse energy, which facilitates achieving higher contrast, saturable absorber, stretcher, two- or three-stage OPCPA based on type I BBO crystals, two 4-pass Ti:Sapphire amplifiers, and vacuum compressor. The cryogenic cooling of the final amplifier (down to 100 K) removes thermal lensing, which allows 10 Hz operation with high laser beam quality. The saturable absorber efficiently reduces the Amplified Spontaneous Emission (ASE) after the CPA oscillator, which is crucial for the solid target irradiation experiments, including the ion acceleration (see Sections 3 and 4). The laser provides ~30 fs, ~ 1 J pulses at the wavelength of ≈ 820 nm with the nanosecond contrast higher than 1010. Employing an f/3 Off-Axis Parabola (OAP) mirror, the pulses are focused down to a 3-4 μm spot (Full Width at Half Maximum, FWHM). The short pulse duration and small focal spot allow achieving the peak irradiance of up to 1020 W/cm2.

The temporal pulse shape on the femtosecond time scale (Figure 1) was measured with the home-built Transient Grating Frequency-Resolved Optical Gating (TG FROG) system (Pirozhkov et al. 2008). The measured FWHM and effective widths of the pulses are τFWHM= 28 fs, τeff= 35 fs without and τFWHM= 35 fs, τeff= 47 fs with the saturable absorber. (The effective width is the ratio of the pulse energy to the peak power.) The pulse duration with the saturable absorber is somewhat larger, because the saturable absorber introduces some high-order dispersion into the spectral phase, which cannot be compensated by the compressor. The power shown in Figure 1 is calculated from the FROG data using the measured on-target pulse energies. The on-target energies without/with the saturable absorber are EL= 880±20 mJ and 720±20 mJ, respectively, which corresponds to the peak powers of P0 = EL/τeff= 25 TW and 15 TW.

The intensity distribution of the laser pulses focused by the f/3 OAP was measured by a microscope objective at full laser power operation; the pulses were attenuated using reflection from wedges and with neutral-density filters. Without the saturable absorber, the focal spot has an elliptical shape with side lobes [Figure 2 (a)]. The major and minor axes of the ellipse have the FWHM sizes of 5.7±0.7 μm and 2.28±0.11 μm, with the effective radius of reff= 2.82±0.10 μm (the errors are standard deviations of shot-to-shot fluctuations). With the saturable absorber, the shape of the focal spot is nearly circular [Figure 2 (b)], with the FWHM of 3.3±0.3 μm and reff= 2.73±0.12 μm. The derived peak intensity is I0 = P0/(πreff2) = 1.0×1020 W/cm2 without and 0.7×1020 W/cm2 with the saturable absorber.

The contrast in different operation modes has been measured with the high-dynamic range 3-rd order cross-correlator (Figure 3). The saturable absorber improves the contrast by a factor of ~100. A similar improvement has been achieved by non-saturated OPCPA operation (two OPCPA stages instead of three) (Kiriyama et al. 2008).

## 3. Proton acceleration experiments with multi-10-TW J-KAREN laser

### 3.1. Experimental setup

A typical schematic layout of the experiments is shown in Figure 4. The OAP focused p-polarized laser pulses onto a tape or ribbon targets at the incidence angle of 45 . The tape target (Nayuki et al. 2003) supplied fresh surface for each shot, which allowed taking advantage of the high-repetition rate laser operation. The tapes were made from polyimide with the thicknesses of 7.5 μm and 12.5 μm. The ribbon targets were made from metal (Al, Au, Pt, Pd, etc.) with the thicknesses down to 200 nm.

The protons were detected by the Time-of-Flight (ToF) spectrometers, CR-39 nuclear track detectors, and Thomson parabola. The ToF spectrometers (Nakamura et al. 2006; Yogo et al. 2007) were installed at the target normal direction and ±22.5 from it. In order to select the proton signal and reduce noise, the ToF spectrometers contained sweeping magnets removing all but the most energetic electrons, Al filters blocking laser and other light, and relatively thin plastic scintillator and the bent light guide that prevented the transmitted x-rays to enter the photomultiplier tube. The ToF spectrometers were absolutely calibrated with the conventional accelerator. The ToF spectrometers provide the proton spectrum immediately after the shot. This together with the constantly moving tape target allowed 1 Hz shooting, which has been used for quick optimization of the proton acceleration conditions. The CR-39 detectors with the range filters were used for the angular distribution and emittance measurements. Thomson parabola ion analyzer was used to check the contribution of other ion species.

To understand the laser-plasma interaction details, we used several plasma diagnostics. The probe beam split by a pellicle from the main pulse was used for shadowgraphy at 820 nm and interferometry at 820 and 410 nm (2ω) (Sagisaka et al. 2004; Sagisaka et al. 2006). To measure the laser energy reflected from and transmitted through the target, we used in-vacuum calorimeters. The calorimeter measuring the transmitted energy was used to measure the on-target laser pulse energy, when the target situated on a motorized 3-axis stage was moved out of the beam. Simultaneously, the third calorimeter measured leakage through one of the dielectric mirrors. After such cross-calibration, the on-target energy in each shot was derived from the dielectric mirror leakage, which allowed obtaining specular reflectivity and transmission.

### 3.2. Results of proton acceleration

We used a broad range of laser and target parameters to study the laser-driven acceleration properties and dependences on parameters. In order to achieve the maximum proton energies, a repetitive operation was employed to optimize the laser contrast, target position, pulse duration, etc.

The dependence of the maximum proton energy on the effective pulse duration is shown in Figure 5. The pulse duration was varied by moving a grating in the compressor. The laser pulse shape was measured using the TG FROG (Figure 1) (Pirozhkov et al. 2008). The spectrum and spectral phase measured with the TG FROG at some grating position allow calculating the shape of the laser pulse at any other grating position with high accuracy, as it was checked by direct comparison of the measured and calculated pulses. The effective pulse duration in Figure 5 is therefore calculated from the TG FROG data obtained with the shortest pulse. The dependence of the maximum proton energy on the pulse duration is rather smooth, with the maximum at somewhat elongated pulse. This can be understood using the model of electrostatic acceleration of protons at the rear side of the target (Mora 2003; Fuchs et al. 2006) with the additional limit that the acceleration distance equals the sheath diameter (Robson et al. 2007). The dependence of the proton energy on the pulse duration obtained from this model (the dashed curve in Figure 5) agrees well with the measurements.

The femtosecond pulses typically have a complicated structure in time. In particular, they have several kinds of preceding light, such as the ASE, prepulses, and picosecond pedestal. The preceding light can damage the target and create the preformed plasma well before the main pulse. To understand the influence of the preformed plasma on the proton acceleration, we employed the time-resolved interferometry using the femtosecond probe pulse (Sagisaka et al. 2004; Sagisaka et al. 2006). Figure 6 shows the results of interferometry taken at 50 ps before the main pulse arrival. The ion spectra at the target normal direction recorded simultaneously with the interferograms shown in Figure 6 are shown in Figure 7. In the case of a relatively low contrast (~5×106), the preplasma with the size of few hundred μm was formed [Figure 6 (a)], and the proton energy was 2.3 MeV. On the other hand, when the high contrast mode was used (~ 5×1010), the preplasma was not detectable [Figure 6 (c)], which means it was smaller than ~20-30 μm. The maximum proton energy in this case was 3.5 MeV. The smaller proton energy in the case of lower contrast can be explained by the rear surface disruption and/or bending (Mackinnon et al. 2001; Lindau et al. 2005). Interestingly, when we adjusted the duration of the ASE in the lower-contrast case (no saturable absorber, contrast ~5×106) by shifting the gating time of the Pockels Cell (PC) by 300 ps, the proton energy increased up to 4.1 MeV in some shots; the preplasma size was in this case intermediate [Figure 6 (b)]. The proton energy higher than in the case with the saturable absorber can be understood by larger laser power and intensity, which were achieved without the saturable absorber, by increased absorption in the preformed plasma (Gibbon & Bell 1992; Borghesi et al. 1999; Ping et al. 2008; Pirozhkov et al. 2009a), and by the laser pulse self-focusing in the preplasma with the optimum scale length (Bychenkov et al. 2001; McKenna et al. 2008).

Taking advantage of the repetitive operation, we studied the stability of the proton acceleration (Figure 8). Although the case with the optimum preplasma allowed achieving higher proton energies in some shots, the proton acceleration was less stable than in the case of high laser contrast. We measured the maximum proton energies at the target normal direction (0 ) and at 22.5 from normal in 13 (40) consecutive shots without (with) the saturable absorber. In the case of higher contrast, the average proton energy was higher and fluctuations were smaller, which is important for many applications requiring stable ion beam. Further, in the high-contrast case the maximum proton energy at 0 was always larger than at 22.5 . In the case of lower contrast, the shot-to-shot fluctuations were large, and the maximum proton energies at these two angles were nearly same. Instability of the proton acceleration in the lower contrast case can be explained by the unstable nature of the preplasma itself, as well as relativistic self-focusing, which is also a kind of instability (Litvak 1970). Angular distributions of proton beam at different contrast conditions are described in details in (Yogo et al. 2008).

It has been shown in simulations (Esirkepov et al. 2006) and experiments (Neely et al. 2006; Antici et al. 2007; Ceccotti et al. 2007) that very thin (sub-micrometer to nanometer-scale) targets can provide higher proton energy and larger conversion efficiency, provided that the laser contrast is sufficiently high so that the target is not damaged by the preceding light. We compared the proton acceleration from ribbon targets with the thickness from 1 μm to 200 nm. The proton energies from 1 μm thick Au targets were larger than from thinner targets (Figure 9). Although the nanosecond contrast was sufficiently high, the target was probably disturbed by the picosecond pedestal or prepulses at few tens of picoseconds before the main pulse (Figure 3).

## 4. On the contrast of high-power lasers

The laser contrast strongly affects ion acceleration. In particular, in the TNSA regime higher ion energy is expected from thinner target in the ideal case, but in real experiments the rear surface of very thin targets is perturbed due to the preplasma formation, so there is an optimum target thickness (Kaluza et al. 2004). The ASE can even turn the originally solid-density target into a near-critical density plasma cloud (Matsukado et al. 2003; Yogo et al. 2008), so the acceleration mechanism changes, and the ions are accelerated by a long-living charge separation electric field, sustained by a quasistatic magnetic field of dipole vortex (Bulanov et al. 2005; Bulanov & Esirkepov 2007; Fukuda et al. 2009).

In order to understand the influence of the laser contrast in the described experiments, we performed the laser contrast diagnostics based on the target reflectivity measurement. The reflectivity was measured using calibrated calorimeters at full power operation in the real shooting conditions. The detailed description of this technique and experiments performed at three different laser systems can be found in (Pirozhkov et al. 2009a; Pirozhkov et al. 2009b). The data obtained with J-KAREN laser are shown in Figure 10.

The data were taken with the saturable absorber present and 3-stage OPCPA, the contrast was ~ 5×108 with the ASE duration of 3 ns. The dependence of the reflectivity on the target position [Figure 10 (a)] exhibits a dip at best focus position T= 0. Such dip corresponds to the insufficient laser contrast. The specular reflectivity decreases due to both the increased absorption in the preplasma and the beam break-up. The dependence of the reflectivity on the average intensity and fluence [Figure 10 (b)] shows that the reflectivity was still high at the average intensity of ~ 2×1017 W/cm2, which is ~ 100 times smaller than the intensity at best focus. Therefore, a ~ 100-fold improvement of the contrast was necessary to avoid the preplasma formation by the ASE. This factor had been achieved by using non-saturated (2-stage) OPCPA operation, which was used to shoot sub-μm targets (Figure 9). However, in the latter case the picosecond pedestal or prepulses might be able to produce the preplasma, which led to the decreased proton energies observed in the case of 200 nm targets.

## 5. Focusing of laser-driven proton beams with the permanent magnet quadrupoles

The perspective mechanisms of laser-driven ion acceleration promise to provide quasi-monoenergetic, low-divergence ion beams (Kuznetsov et al. 2001; Esirkepov et al. 2004; Esirkepov et al. 2006). However, in the present experiments the typical ion beam divergence is ~10 , and the energy spectrum is wide (energy spread ~100%) (Borghesi et al. 2006). This is disadvantageous for many applications of the laser-driven ion beams, which are possible at present. Here we can point out the radiobiological studies (Yogo et al. 2009), ion beam injector to the postaccelerator (Krushelnick et al. 2000; Cowan et al. 2004), etc. Therefore, it would be desirable to modify the ion beam divergence and spectrum. There were several proposals and demonstrations of various techniques, including the use of a curved target (Bulanov et al. 2000; Sentoku et al. 2000; Ruhl et al. 2001; Patel et al. 2003) (focusing or collimation of the proton beam), laser-driven plasma microlens (Toncian et al. 2006) (proton beam focusing and energy selection), phase rotation using a radio-frequency electric field (Nakamura et al. 2007; Ikegami et al. 2009; Wakita et al. 2009) (modification of the proton energy spectrum and beam divergence), and use of permanent magnet quadrupoles (PMQs) (Schollmeier et al. 2008; Ter-Avetisyan et al. 2008; Nishiuchi et al. 2009) (focusing or collimation of the ion beam, energy band selection). In this Section, we describe the experiment in which the efficient proton beam manipulation with the PMQs was demonstrated (Nishiuchi et al. 2009). The feature of this experiment is the 1 Hz repetition rate and the large acceptance angle of the PMQs, which allowed achieving high proton flux.

The experiment was performed with J-KAREN laser with the on-target pulse energy of 0.7 J, pulse duration of 30 fs, peak irradiance of ~1020 W/cm2, and the ASE contrast and duration of 107 and 1 ns, respectively. The setup was similar to the one shown in Figure 4. However, the pair of PMQs was installed at the target rear side, as shown in Figure 11.

Originally, the proton beam with the energy band from 1.9 to 2.8 MeV had a typical divergence of 10 (half angle), as it is demonstrated in the frame (a). The acceptance angle of the first PMQ was also ~10 (half angle). Thus, nearly all protons were accepted at this stage. The first PMQ focused the protons in the vertical and defocused in the horizontal planes. Due to the defocusing, some of the protons were not collected with the second PMQ. Those protons which were collected were further focused in the horizontal and defocused in the vertical planes with the second PMQ. As a result, the focus point was formed at the distance of 650 mm from the target. The proton beam profiles recorded with the CR-39 nuclear track detectors at the best focus as well as several other positions are shown in the frames (b) – (g) of Figure 11 (the proton energy range is 2.2 to 3.1 MeV). At the best focus, the CR-39 image has the dimensions of ~3 mm × 8 mm. However, due to the etch pit overlapping (detector saturation), this visible spot size is overestimated, and the real spot was smaller.

Apart from the proton beam profile, we also measured the proton energy spectra with the ToF spectrometer situated at 1.93 m from the target. The original spectrum (without the PMQs) is shown in Figure 12 (a) by the line 2. With the PMQs, the spectrum becomes quasi-monoenergetic due to the strong chromatic aberrations of the PMQs (namely, most of the

low-energy protons, except those near the axis, are strongly deflected by the first PMQ and do not pass through the aperture of the second PMQ).

Each frame (b) – (g) in Figure 11 also contains the inset, which shows the result of the Monte-Carlo simulation of the proton beam profile at the corresponding position. The parameters of the original proton beam (spectrum, divergence) and the beam transport system in the simulation was set in accordance with the experimental conditions. The close similarity of the experimental beam profiles with the simulation suggests that the alignment accuracy was sufficient in the experiment; we found that the accuracy of the magnet positioning should be ~100 μm. Additional evidence of the similarity is shown in Figure 12 (a), where the spectrum measured with the ToF is compared with the simulated one. The similarity of the experimental results and the simulation allows us to derive conclusions about the detailed parameters of the focused proton beam. In particular, we can simulate the proton energy spectrum at the focal plane (this is not same as the spectrum measured with the ToF at the distance of 1.93 m). The simulated spectrum is shown in Figure 12 (b); here the protons passing through the 3 mm diameter aperture are included. The spectrum is quasi-monoenergetic, with the energy of 2.4±0.1 MeV. The transport efficiency of the beamline for the energy range of 2.3 – 2.5 MeV was ~0.3. The loss was due to the second PMQ, as shown in the schematic layout in Figure 11. The efficiency of 0.3 should be compared with the transport efficiency of the divergent beam without the PMQs, which is ~ 1.7×10-4 (1.7×103 times smaller). Simulation also allowed calculating the duration of the proton bunch, which was ~1 ns. This is much shorter than the typical achievable value, which is determined by the strong dispersion of the usual proton beam with a large energy spread.

The passive nature of the magnetic beamline led to the high stability of the spectrum after the PMQ pair. The pointing stability of the proton beam was 0.25±0.1 (standard deviation of shot-to-shot fluctuations). The instability of the proton number within the energy range of 2.4±0.1 MeV was 20%; this value included the fluctuations of the proton number, divergence, and pointing of the proton beam during the acceleration stage, originating from the laser, target, and plasma instabilities.

The demonstrated technique of the ion beam focusing can be useful in many applications of the laser-driven ion beams, including such field as high-energy density physics, radiography, nuclear physics, astrophysics, radiobiological studies, chemistry, material sciences, etc.

## 6. Radioactivation experiments

Multi-MeV laser-driven proton beams can induce nuclear reactions (Ledingham et al. 2003; McKenna et al. 2003). In fact, these nuclear reactions were used for the proton beam diagnostic in many experiments (Hatchett et al. 2000; Snavely et al. 2000; McKenna et al. 2004; Clarke et al. 2008). Another possible application of the nuclear reactions induced by laser-driven proton beams is the thin layer activation (TLA) (Racolta et al. 1995), which allows studying the wear of tools, for example cutting tools made from cubic boron nitride (BN) or artificial polycrystalline diamond (DIA) (Conlon 1985; Vasváry et al. 1994). In TLA, the thin layer of tool is activated by selecting the appropriate energy range of the proton beam. Measuring the residual activity, it is possible to determine the loss of the surface material with the high sensitivity. Various isotopes can be activated, including iron, titanium, chromium, etc., which opens wide possibilities for the industrial diagnostic. The typical reaction threshold is from few to 10 MeV, which means that compact laser systems can be used.

In this Section, we describe the results of the proof-of-principle experiment on the BN target activation (Ogura et al. 2009). The experimental setup is shown in Figure 13 (a). The parameters of J-KAREN laser used in this experiment were as follows: the pulse energy of ~1 J, the pulse duration of 30 fs, the peak irradiance of ~1020 W/cm2, the ASE contrast of higher than 1010. The target for the laser was polyimide tape. At the rear side of the tape, the BN sample was installed. The laser-driven proton beam induced the reaction 11B(p,n)11C, which has the threshold of 2.76 MeV. The maximum proton energy in this experiment ranged from 2.8 to 3.5 MeV, larger than the reaction threshold.

The isotopes 11C produced in the nuclear reaction decay through the positron emission with the half-life time T1/2 = 20.39±0.02 min (ENSDF, NNDC Online Data Service, ENSDF database [http://www.nndc.bnl.gov/ensdf/]). The positrons annihilate with the emission of two photons with the energy of 0.511 MeV, directed at 180 to each other. The annihilation photon spectrum recorded with the GSO scintillation counter (Leo 1987) is shown in Figure 13 (b). From the decay curve shown in the inset, the half-life time can be deduced: T1/2 = 20.9±0.7 min, which corresponds to the decay time of 11C. After 60 laser shots, the activity of the sample was measured to be 11.1±0.4 Bq. Using the 10 Hz laser operation during 10 minutes (6000 shots), the activity in the kBq range can be obtained, which is sufficient for the typical TLA diagnostic. Finally, we note that, unlike the situation with many other applications, the large divergence angle and the broad energy spectrum of the laser-induced proton beam can be convenient for the thin layer activation industrial diagnostic.

## 7. Conclusion

In conclusion, the laser-driven ion acceleration is the perspective new technique. The laser-driven ion beams have unique properties, such as ultrashort bunch duration, low emittance, small source size, and large particle number. The laser-driven acceleration is a very compact process, which takes place on the micrometer scale. For many applications, a repetitive ion beam is desirable, which can be achieved employing femtosecond laser systems. We described the performance of laser and properties of proton beam by the example of experiments performed in the Advanced Photon Research Center, Japan Atomic Energy Agency with J-KAREN laser. In particular, we described the dependence of the maximum proton energy on the laser pulse duration and found the optimum of few hundred femtoseconds for the given experimental conditions. We also depicted the influence of laser contrast and demonstrated the method of its diagnostic. We described two application experiments, in which the stable, repetitive (1 Hz) laser-driven proton beam was focused by the permanent magnet quadrupoles, and was used for the BN target activation, which can be applicable in the industrial testing of tools and mechanisms using the thin layer activation technique.

## Acknowledgments

We are grateful for the expert support of J-KAREN laser team. This work was supported by the Special Coordination Funds for Promoting Science and Technology (SCF) commissioned by the Ministry of Education, Science, Sports and Culture (MEXT) of Japan and partly by Specially Promoted Education and Research by MEXT.

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Written By

Alexander S. Pirozhkov, Hiroyuki Daido, Mamiko Nishiuchi and Koichi Ogura

Published: February 1st, 2010