\r\n\t \r\n\tThe aims of this book are to present the updates and advances in the field of resuscitation including AHA guidelines, latest evidence for the airway protection equipment, the role of AED in cardiac arrest, latest advances and the evidence including ongoing updated research including return of spontaneous circulation and post resuscitation care and support including neurological and hemodynamic stability. \r\n\t \r\n\tThe content of this book will be focused on latest research in the field which will create a concise updated information for medical, nursing and paramedical personnel. Furthermore, the book will also touch upon controversial topics in resuscitation and will try to bring out latest evidence intending to solve the controversies in the field of resuscitation. This book will be an excellent extract of all available updates and ongoing research for a complete knowledge of resuscitation.
",isbn:null,printIsbn:"979-953-307-X-X",pdfIsbn:null,doi:null,price:0,priceEur:0,priceUsd:0,slug:null,numberOfPages:0,isOpenForSubmission:!1,isSalesforceBook:!1,isNomenclature:!1,hash:"4e1d9c7965a911a1d2c3c1337a16acc5",bookSignature:"Dr. Mayank Gyan Vats",publishedDate:null,coverURL:"https://cdn.intechopen.com/books/images_new/8226.jpg",keywords:"CPR, Airway, Intubation, AED, BLS, ACLS, Cardiac Arrest, Arrhythmia, Advances",numberOfDownloads:null,numberOfWosCitations:0,numberOfCrossrefCitations:0,numberOfDimensionsCitations:null,numberOfTotalCitations:null,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"October 30th 2019",dateEndSecondStepPublish:"November 20th 2019",dateEndThirdStepPublish:"January 19th 2020",dateEndFourthStepPublish:"April 8th 2020",dateEndFifthStepPublish:"June 7th 2020",dateConfirmationOfParticipation:null,remainingDaysToSecondStep:"3 years",secondStepPassed:!0,areRegistrationsClosed:!0,currentStepOfPublishingProcess:5,editedByType:null,kuFlag:!1,biosketch:null,coeditorOneBiosketch:null,coeditorTwoBiosketch:null,coeditorThreeBiosketch:null,coeditorFourBiosketch:null,coeditorFiveBiosketch:null,editors:[{id:"148941",title:"Dr.",name:"Mayank",middleName:"Gyan",surname:"Vats",slug:"mayank-vats",fullName:"Mayank Vats",profilePictureURL:"https://mts.intechopen.com/storage/users/148941/images/system/148941.jpg",biography:"Dr. Mayank Vats is a Senior Specialist, Interventional Pulmonologist, Pulmonologist, Intensivist, and Sleep Physician at Rashid Hospital and Dubai Hospital and developed the interventional pulmonology department in Rashid Hospital. Before coming to the United Arab Emirates, he was a consultant in Respiratory Medicine, Critical Care Medicine, and Sleep Medicine at Escorts Heart Institute and Apollo Hospital, New Delhi India, a tertiary level of care hospital in India. Dr Vats’s interest is to utilize his professional knowledge and interpersonal skills in order to provide the highest degree of patient care and satisfaction. Having worked in a busy tertiary level teaching hospital and specialty corporate hospitals as a consultant, he has been exposed to the complete spectrum of respiratory, critical care and sleep medicine.",institutionString:"Rashid Hospital",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"2",totalChapterViews:"0",totalEditedBooks:"3",institution:{name:"Rashid Hospital",institutionURL:null,country:{name:"United Arab Emirates"}}}],coeditorOne:null,coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"16",title:"Medicine",slug:"medicine"}],chapters:null,productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"},personalPublishingAssistant:{id:"247865",firstName:"Jasna",lastName:"Bozic",middleName:null,title:"Ms.",imageUrl:"https://mts.intechopen.com/storage/users/247865/images/7225_n.jpg",email:"jasna.b@intechopen.com",biography:"As an Author Service Manager, my responsibilities include monitoring and facilitating all publishing activities for authors and editors. From chapter submission and review to approval and revision, copyediting and design, until final publication, I work closely with authors and editors to ensure a simple and easy publishing process. I maintain constant and effective communication with authors, editors and reviewers, which allows for a level of personal support that enables contributors to fully commit and concentrate on the chapters they are writing, editing, or reviewing. I assist authors in the preparation of their full chapter submissions and track important deadlines and ensure they are met. I help to coordinate internal processes such as linguistic review, and monitor the technical aspects of the process. As an ASM I am also involved in the acquisition of editors. Whether that be identifying an exceptional author and proposing an editorship collaboration, or contacting researchers who would like the opportunity to work with IntechOpen, I establish and help manage author and editor acquisition and contact."}},relatedBooks:[{type:"book",id:"3309",title:"Respiratory Disease and Infection",subtitle:"A New Insight",isOpenForSubmission:!1,hash:"2e85d47bf0576f1c2ccf642156ccbda2",slug:"respiratory-disease-and-infection-a-new-insight",bookSignature:"Bassam H. Mahboub",coverURL:"https://cdn.intechopen.com/books/images_new/3309.jpg",editedByType:"Edited by",editors:[{id:"148941",title:"Dr.",name:"Mayank",surname:"Vats",slug:"mayank-vats",fullName:"Mayank Vats"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"6151",title:"Noninvasive Ventilation in Medicine",subtitle:"Recent Updates",isOpenForSubmission:!1,hash:"77e2fc8d909ac2458e0087490ea02a6d",slug:"noninvasive-ventilation-in-medicine-recent-updates",bookSignature:"Mayank Vats",coverURL:"https://cdn.intechopen.com/books/images_new/6151.jpg",editedByType:"Edited by",editors:[{id:"148941",title:"Dr.",name:"Mayank",surname:"Vats",slug:"mayank-vats",fullName:"Mayank Vats"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"5449",title:"Sleep Apnea",subtitle:"Recent Updates",isOpenForSubmission:!1,hash:"a24e07959eedce97032e4191b88003bb",slug:"sleep-apnea-recent-updates",bookSignature:"Mayank G. Vats",coverURL:"https://cdn.intechopen.com/books/images_new/5449.jpg",editedByType:"Edited by",editors:[{id:"148941",title:"Dr.",name:"Mayank",surname:"Vats",slug:"mayank-vats",fullName:"Mayank Vats"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"6550",title:"Cohort Studies in Health Sciences",subtitle:null,isOpenForSubmission:!1,hash:"01df5aba4fff1a84b37a2fdafa809660",slug:"cohort-studies-in-health-sciences",bookSignature:"R. Mauricio Barría",coverURL:"https://cdn.intechopen.com/books/images_new/6550.jpg",editedByType:"Edited by",editors:[{id:"88861",title:"Dr.",name:"R. Mauricio",surname:"Barría",slug:"r.-mauricio-barria",fullName:"R. Mauricio Barría"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9500",title:"Recent Advances in Bone Tumours and Osteoarthritis",subtitle:null,isOpenForSubmission:!1,hash:"ea4ec0d6ee01b88e264178886e3210ed",slug:"recent-advances-in-bone-tumours-and-osteoarthritis",bookSignature:"Hiran Amarasekera",coverURL:"https://cdn.intechopen.com/books/images_new/9500.jpg",editedByType:"Edited by",editors:[{id:"67634",title:"Dr.",name:"Hiran",surname:"Amarasekera",slug:"hiran-amarasekera",fullName:"Hiran Amarasekera"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"1591",title:"Infrared Spectroscopy",subtitle:"Materials Science, Engineering and Technology",isOpenForSubmission:!1,hash:"99b4b7b71a8caeb693ed762b40b017f4",slug:"infrared-spectroscopy-materials-science-engineering-and-technology",bookSignature:"Theophile Theophanides",coverURL:"https://cdn.intechopen.com/books/images_new/1591.jpg",editedByType:"Edited by",editors:[{id:"37194",title:"Dr.",name:"Theophile",surname:"Theophanides",slug:"theophile-theophanides",fullName:"Theophile Theophanides"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3161",title:"Frontiers in Guided Wave Optics and Optoelectronics",subtitle:null,isOpenForSubmission:!1,hash:"deb44e9c99f82bbce1083abea743146c",slug:"frontiers-in-guided-wave-optics-and-optoelectronics",bookSignature:"Bishnu Pal",coverURL:"https://cdn.intechopen.com/books/images_new/3161.jpg",editedByType:"Edited by",editors:[{id:"4782",title:"Prof.",name:"Bishnu",surname:"Pal",slug:"bishnu-pal",fullName:"Bishnu Pal"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3092",title:"Anopheles mosquitoes",subtitle:"New insights into malaria vectors",isOpenForSubmission:!1,hash:"c9e622485316d5e296288bf24d2b0d64",slug:"anopheles-mosquitoes-new-insights-into-malaria-vectors",bookSignature:"Sylvie Manguin",coverURL:"https://cdn.intechopen.com/books/images_new/3092.jpg",editedByType:"Edited by",editors:[{id:"50017",title:"Prof.",name:"Sylvie",surname:"Manguin",slug:"sylvie-manguin",fullName:"Sylvie Manguin"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"371",title:"Abiotic Stress in Plants",subtitle:"Mechanisms and Adaptations",isOpenForSubmission:!1,hash:"588466f487e307619849d72389178a74",slug:"abiotic-stress-in-plants-mechanisms-and-adaptations",bookSignature:"Arun Shanker and B. Venkateswarlu",coverURL:"https://cdn.intechopen.com/books/images_new/371.jpg",editedByType:"Edited by",editors:[{id:"58592",title:"Dr.",name:"Arun",surname:"Shanker",slug:"arun-shanker",fullName:"Arun Shanker"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"72",title:"Ionic Liquids",subtitle:"Theory, Properties, New Approaches",isOpenForSubmission:!1,hash:"d94ffa3cfa10505e3b1d676d46fcd3f5",slug:"ionic-liquids-theory-properties-new-approaches",bookSignature:"Alexander Kokorin",coverURL:"https://cdn.intechopen.com/books/images_new/72.jpg",editedByType:"Edited by",editors:[{id:"19816",title:"Prof.",name:"Alexander",surname:"Kokorin",slug:"alexander-kokorin",fullName:"Alexander Kokorin"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}]},chapter:{item:{type:"chapter",id:"74141",title:"Italian Crisis Management in 2020",doi:"10.5772/intechopen.94894",slug:"italian-crisis-management-in-2020",body:'
1. Introduction
Dealing with complexity and reducing uncertainty during 2020 crisis is a priority, for Countries, Critical Infrastructures, and companies.
Due to the interdependency of Critical Infrastructures, companies, and the civil society their protection and management represent a significant challenge and, somehow, an opportunity.
The present contribution aims to support the understanding of the tangled pandemic scenario, studying the interdependencies between different sectors and their supply chain, proposing a model addressed to the complexity management for ensure the Business Continuity both of Critical Infrastructure and companies.
The Italian response to the crisis generated by the pandemic was observed, from the study of the impact of the crisis on Critical Infrastructures, to the response strategies, the remediation plans, passing through the reference standards on business continuity and supply chain (in the ISO family of standards).
The imposed lockdown has led to a forced acceleration of digitization, with the challenges and opportunities that could be derived from it.
The crisis management, supported by the experience generated by the avian influenza, together with the support tools provided by the Italian government has proved to be effective and efficient, also relaunching several SMEs through their productive conversion.
The human factor has become evident as the cornerstone of any service, from the provision of essential services falling within the competence of the Critical Infrastructures, which have involved a particular attention to the continuous security and business protocols to be followed, to the most disparate production sectors. It is also necessary to remember how the interconnection between the different sectors and services now characterizes our reality, and therefore how the so call “What-If Analysis” s fundamental in the development of decision support tools for crisis management. In this context is clear that resilience is founded on risk analysis and the drawing of recovery plans, together with measures for an increased control over the value chain.
2. Addressing complexity and impacts of pandemic in critical infrastructure
Dealing with complexity and reducing uncertainty during 2020 crisis is a priority for Countries, Critical Infrastructures, and companies.
Complexity could represent a risk but also an opportunity to create a new competitive advantage.
Society is dependent on composed critical networks, becoming more complex as are strong interdependent both within and between infrastructure systems [1].
Nowadays, complexity and uncertainty assess the search for new and effective management strategies and methods. Embracing unpredictability and planning to adapt is crucial to manage the complexity that cannot be eliminated, although, it can be reduced to manageable levels. Complexity and vulnerability of Critical Infrastructure systems has been explored and assessed [2, 3].
Complexity is related with composite systems and problems that are dynamic, unpredictable, and multi-dimensional. It consists of a collection of interconnected relationships and parts. Unlike traditional “cause and effect” or linear thinking, complexity science is characterized by nonlinearity [4]. Complexity management needs to consider several layouts of complexity, in fact an IC or a company internal value chain is strongly dependent on external complexity.
For each area of complexity regulation, as avoidance and reduction related to causes, transfer, and division, exist several theories, approaches and methods.
Effective complexity management aim to develop an appropriate and effective incident response plan. Finally, complexity must be addressed proactively.
In fact, in such complex scenario, different actors (institutional and non) have responded to the crisis in multiple ways, according to the regulations issued. Moreover, these troubled times show how strategic and essential are some sectors.
In the crisis generated by the pandemic it has been confirmed that the daily life of the citizens depends on the reliability of the Critical Infrastructures (CI) to supply essential services such as energy and water. In recent years, Critical Infrastructure control systems have become more complex, with increasingly interconnected devices; a trend that will probably continue with the Internet of Things.
The need for increased resilience to resist extreme events of both natural and malicious origin has become more acute. With Critical Infrastructure continuously exposed to threats, especially cyber-attacks, there are severe security implications, most notably in the energy sector which is ranked as one of the most affected sectors with the highest incident costs [5]. Any attack of this nature is likely to have knock-on effects on a country’s overall economy and the lives of its citizens.
The pandemic, all in all, has had modest effects on the electrical service. Electricity consumption has been reduced by about 10% on average, but with a very uneven distribution on the Italian territory. Fortunately, the phenomenon has been well controlled and there have been no perceptible effects, but it is easy to imagine the consequences of possible inefficiencies. The effect of the pandemic could be very marked on geopolitical balances, in a context of possible tensions deriving from the rebalancing of the primary energy market and the challenge of the Fourth Industrial Revolution (4IR) [6].
The energy issue brings us back to the more general field of critical infrastructures: electricity and energy system, communication networks, infrastructures for the transport of people and goods (air, sea, rail and road), health system, economic-financial circuits, administrative and state organizations and bodies.
What happened on the Istituto Nazionale della Previdenza Sociale (the Italian Social Security), website is a symptom of a strong criticality in the Country System, where technical shortcomings make the fundamental rights of citizens even more vulnerable, and how IC and companies must equip themselves to manage crisis situations that are not predictable. For this reason there have been several episodes in Italy which have triggered the alarm by the Centro Nazionale Anticrimine Informatico per la Protezione delle Infrastrutture Critiche (CNAIPIC - National Anti-Crime Information Centre for the Protection of Critical Infrastructures).
In terms of crisis management, thanks to the experience of avian influenza (H5N1), which has highlighted how the human factor is the most valuable element for any company and as such must be safeguarded and protected, operators of critical infrastructure have been able to develop a series of effective initiatives, as demonstrated by the fact that no essential service, i.e. the supply of gas, water, electricity, transport, etc. has suffered interruptions or dysfunctions in recent months. And this despite the problems related to difficulties in supply, reduced mobility, the presence of staff in quarantine fiduciary and/or infected and considering the commitment of companies to safeguard the health of their workers.
This achievement is the result of an effort which in recent years has seen a significant change in the role of the security managers, which has shifted to the top management in order to bring strategic choices back to specific task forces capable of having a prompt impact on all levels of the company’s organization, being equipped with the financial and decision-making capacity appropriate to the criticality of the situation [7].
2020 long time crisis and consequent lock down were managed asking to every operators of critical services to maintain business continuity and to guarantee services if critical. This means that not only critical infrastructures at national level, but also critical infrastructures at regional or city or province level had to maintain operation, even having the supply chains partly or completely locked and also even having manpower partly or completely in smart working.
The Office of the Military Advisor of the Presidency of the Council, in consideration of the necessity to guarantee the essential services provided by Critical Infrastructures, has provided the precautionary principles, to which Critical Infrastructure Operators are required to comply in order to contain and contrast the spread of the pandemic, while ensuring the continuity of the supply of essential services, the operability of the facilities and the security of the personnel involved.
These lines suggest, first, a reduction in the number of staff working in situ by reducing activities to those that cannot be postponed for business continuity, and to review the maintenance programs, limiting them to those that cannot be postponed and postponing those that are not indispensable, promoting the adoption of smart working at all levels, necessary for the continuity of the service. The Precautionary Principles highlight the need to provide specific training and tools to operators to prevent and combat the threat of cybersecurity, the importance of which is growing today, to equipping all staff with adequate IT support, including the use of dedicated connections, VPN systems and anything else in order to ensure adequate levels of cybersecurity, including the issue of appropriate rules of conduct by staff working in smart working mode.
Furthermore, is required to prepare all the necessary measures related to sanitization.
The Companies are invited to organize the personnel involved in activities that cannot be postponed at the work sites or field operations in teams composed of the minimum number of people necessary for the safe execution of the various activities. The composition of each team, to increase its resilience, must not, where possible, change over time and specific procedural measures must be taken to avoid, or limit to a minimum, physical interaction between several teams.
With regard to the management of the control and management rooms, given that it is necessary to ensure their functionality in all conditions, it is recommended that all useful measures be taken to contain the pandemic; organizing the staff into several teams and adopting specific and more stringent safeguards for this type of personnel, for example, measures and/or adequately equipping several rooms, possibly in different locations, to allow the alternation of shifts in different rooms and/or sanitized each shift change [8]. Another taken measure was the “voluntary segregation”: the provision of temporary accommodation for groups of people who will operate in the control center for a period of not less than 14 days without physical contact with external personnel. The spaces to which such staff have access will be forbidden to those who do not implement voluntary segregation. To guarantee the continuous rotation of the activities, a second team of staff is set up at the same time, already in isolation at their homes.
Telespazio has set up a three-level system for its Space Center which, before entering the control room, requires a further period of voluntary quarantine within a camp facility located at the Fucino site [9].
The theme of cyber-security is particularly relevant in an increasingly interconnected world where threat vectors multiply and can affect the vulnerabilities of Critical Infrastructures. Moreover, the low level of cybersecurity preparedness of the country system is also reflected in low awareness among citizen-users.
In view of the above, we can say that for the management of emergencies and crises first of all it is necessary to develop a culture of security, supported by the necessary tools and strategies, also considering that we are moving towards the increasing digitalization of any area of the country. In order to do this we can combine the creation of high potential and distributed networks, to avoid in case of stress of infrastructure use, domino effects. It is not possible today to imagine an area of the country that is not covered by essential infrastructures and services that respond to adequate minimum levels of service delivery and security, especially cybersecurity.
It is therefore also essential to start a training process in line with the needs of the world of work and thus adapt to the new professions, together with a plan for the conversion of skills towards new professional qualifications [10].
A fundamental and new aspect of this crisis, which has led to a rethinking of the management of Critical Infrastructures, is that there was a clear “ day before” (in Italy between 10th and 11st March) and a lack of clarity in the “day after”. There is still the sensation of a prolonged crisis and the passage to a remote working that has reduced social relations. This situation has also led to a discontinuity in the visibility that the employer has towards his employees (with respect to how he is and what he feels) that had never been experienced before, while the knowledge of the human model is crucial.
When we make a reading of complexity, we consider a company (or a CI) and analyze it in all that is the flow of its value chain and we retrace all the places and moments of a not physiological complexity.
One type of challenge for Critical Infrastructure Protection is about the dependencies and interdependencies among different Critical Infrastructures [11].
In the context of this extremely long lock-down we had an enormous complexity of relations with suppliers and with those who had to remain in continuity and we would find in the re-opening a strong discontinuity, also in understanding for example the rules with which it was possible to re-open and the responsibilities (in fact, the provision of a suitable team that knows how to interpret the rules is also part of crisis management).
2.1 The Italian production strategy during the 2020 pandemic: statal measures and production conversion
Italian SMEs have worked out an appropriate response strategy to the crisis caused by the 2020 pandemic.
Starting from the importance of the role of each individual entrepreneur, through the constant and daily collection of information on a formal and informal basis, it was possible to identify the strategic levers and focus on new core businesses, based on corporate liquidity, assets and resources.
It emerged that the creation of balanced strategic levers, the make/buy balance, together with the dialog with the stakeholders represented a fundamental element for the conception of a response strategy that represented an example of business resilience.
The crisis has certainly been, and still is, an opportunity to examine which lessons are learning for the future creation of resilience-oriented protocols [12].
There are many Italian companies that have reacted to the crisis by reconverting their production.
Phase two, co-existence with the pandemic, began on 4th May 2020. The Prime Minister’s Decree issued by the Government has made mandatory the use of the mask in closed places accessible to the public, such as public transport and shops. Wearing the mask is mandatory in all situations where “it is not possible to continuously guarantee a safe distance” [13].
Given the emergency and lack of access to this personal protective equipment, more and more companies have chosen to make a concrete contribution and boost their activities after the lockdown by aiming at the reconversion of production chains to manufacture masks. Initiatives that are born to make available the expertise and skills of entire sectors forced by the emergency and the upheaval of daily habits to rebuild their missions and restructure their short, medium- and long-term objectives.
Siare Engineering, an Emilian company specialized in the manufacture of lung ventilators (the unique company in Italy), at the outbreak of the emergency increased its production and changed its export market. In mid-March the company delivered 300 machines to the Civil Protection, originally destined for countries such as South Korea, India, the Philippines and Vietnam, its traditional clients. The company was supported by specialized Army technicians with the aim of producing over 2300 machines, tripling production. Siare Engineering’s efforts were supported by companies such as Ferrari, FCA and Magneti Marelli [14].
Grafica Veneta, a Paduan company active in the printing sector, has reconverted its production to produce 2 million masks. These products, even though they could not be intended for healthcare workers, provided (at a time of dramatic shortage) an initial protection to the population, and were distributed free of charge to the population by the Civil Protection and the Alpini (Italian Army’s mountain infantry).
Mestel Safety, a specialist in snorkeling and diving masks, deposited a patent at the beginning of March to transform this diving equipment into protective masks against contagion [15].
On 23rd March Confindustria Moda launched an adhesion campaign to make masks and PPE, to which 200 companies have immediately joined. A similar initiative was taken by CNA Federmoda. Some of the most important Italian fashion companies responded to the call, such as Armani, Calzedonia, Fendi, Gucci and Valentino.
Prada, on request of the Tuscany Region, has started the production of 80,000 white coats and 110,000 masks [16].
Toscano Alta Sartoria (ex Mabro) has promptly reconfigured its production starting, from March, to produce 3000–4000 masks per day [17].
A choice made also by Valigeria Roncato, a leading company in the sector in the production of luggage made in Italy, which has decided to make a strong contribution to the enduring battle at pandemic by converting its production lines for the production of long-lasting, non-disposable, washable and therefore reusable masks [18]. The core business of the Veneto industry responds to the urgent demand for protective masks that are becoming more and more indispensable.
These solidarity initiatives have been stimulated by the possibility to access incentives to activate the production and supply of medical devices and personal protective equipment (PPE) for the containment and fight against the epidemiological emergency.
And more: to deal with the pandemic, numerous measures have been taken to prevent and contain its expansion and its effects on the economic system. These are emergency measures issued at short distance from each other and linked to each other.
The financial support to SMEs has gone through interventions on the fiscal side, the suspension of the refund of loans, the public guarantee on those granted to companies that have suffered decreases in turnover, a fund for the promotion of Made in Italy, financing.
The objective was to prevent SMEs from shutting down due to lack of liquidity because of the emergency: according to Cerved the system could lose up to 650 billion in revenue between this year and the next.
In this picture, are extremely important the interventions to support the liquidity of the productive network, strongly strengthened by the Legislative Decree n. 23/2020 (so-called Liquidity Decree). This last measure has on one hand modified and on the other hand implemented the extraordinary measures introduced by Decree Law no. 18/2020. This is also thanks to the new regulatory framework for State aid, the EU Commission’s “State Aid Temporary Framework” [19], which has intervened in the meantime. On 14th April 2020, the European Commission authorized the extraordinary support aid schemes provided by Decree Law no. 23/2020. Further interventions to support the liquidity of companies are also contained in Decree-Law No 34 of the 2020.
The economic support measures for businesses adopted with the decrees of March–May 2020 (Decree-Law No 18/2020, Decree-Law No 23/2020 and Decree-Law No 34/2020) are essentially attributable to the following main lines of intervention: liquidity support; export and internationalization support; capitalization support and non-repayable grants; suspension of certain obligations and tax payments, as well as temporary relief on the fixed costs of electricity bills for low-voltage non-domestic users; interventions for companies in crisis, industrial reconversion and development contracts; protection of the national economic and business fabric through changes, some of which are temporary, to the exercise of special powers in sectors of strategic importance (so-called golden power).
Among the measures for companies in crisis, industrial reconversion and development contracts, the following interventions are highly important.
Decree Law No. 18/2020 refinanced the measure of development contracts by €400 million for 2020 (Article 80). The Ministero dello Sviluppo Economico (MISE) Directive of April 15th, 2020 provided for the allocation of resources.
Finally, it should be noted that Law Decree no. 18/2020 authorized the Extraordinary Commissioner for the Epidemiological Emergency to provide funding to companies producing medical devices and personal protective equipment, using INVITALIA as the entity managing the measure. To this end, expenditure of EUR 50 million for 2020 has been authorized (Article 5). The aid scheme was authorized by the EU Commission (on 22nd March 2020). The Ordinance of the Extraordinary Commissioner of 23rd March 2020 (published in the Official Journal on 24 March 2020) implemented the measure.
The resources were assigned to the granting of aid to investment programs aimed at increasing the availability of medical devices and personal protection equipment in the national territory through the expansion of the capacity and/or the reconversion of an existing production unit. The facilities consist of subsidized financing of up to 75% of eligible expenditure. The maximum amount of the facilities that can be granted, in terms of aid (intended as Gross Grant Equivalent), may not exceed 800,000 euros, in accordance with the European Commission Communication of 19th March 2020 - COM (2020) 1863 final - “Temporary Framework for State aid measures to support the economy in the current COVID-19 outbreak”.
Manufacturing masks, gowns, gels and disinfection products, plexiglass spacers, medical devices. These are some of the production reconversions following the pandemic of companies in most of the textile-fashion sector, but also plastics, chemicals, cosmetics, manufacturing, medical, graphics and printing [20].
For some sectors, textiles and chemicals, the new production is opening stable business opportunities in the post 2020 long time crisis, through new channels, which also open opportunities for professional integration.
More than two thirds of companies in the chemical sector, which in the emergency produced alcohol-based disinfectant gels for the hospital sector, are planning to permanently convert, but now intend to extend to direct sales to consumers.
And two thirds of the companies in the plastics sector, which have taken the opportunity to make plexiglass spacers to be installed in the companies, will not stop production. By virtue of a demand that is still expected to be sustained, moreover, more than half of the companies in the textile sector, which are now also aiming to create joint ventures with fashion companies, and almost all the companies in the print sector, which have activated new channels, will maintain active production of masks.
Not all companies, however, are planning to maintain the conversion once the normality is restored, with profound differences between sectors, due to the specificities of the productions.
These are mainly temporary reconversions, on the other hand, for fashion companies that have turned for a few weeks to the production of masks and gowns, as for those in the automotive, cosmetics, medical devices, and manufacturing sectors.
In addition to interventions aimed solely at conversion, the whole world of work has had to face the need to change and adapt to the new situation. Another example of resilience, together with the reconversion of the production of different companies, was the adoption of smart working.
There are data on the transition to remote working collected by Associazione Italiana Esperti Infrastrutture Critiche (AIIC) with the help of other companies. It became clear that before the crisis and therefore until 2019 in companies 71% of employees did not even know what remote working was. During the pandemic 97% of people said they had been working remotely all the time and 43% of people interviewed said they would continue to work remotely.
Regarding the impact on the IT budget: 30% of companies said that investments on the 2020 roadmap projects reset and/or moved to 2021 or suspended.
In contrast, 30% of companies stated that investments will continue without any impact on the 2020 roadmap projects.
Finally, 60% of companies say they still do not know how to proceed with the investments.
The company management, however, has the advantage of being able to provide incentives for sanitization and safety at work: for companies are introduced incentives for sanitization and increased safety at work, through the granting of a tax credit equal to 50% of expenses up to a maximum of 20 thousand euros, and contributions through the establishment of an Inail fund.
The pandemic emergency has not only produced a strong acceleration of digital transformation, smart working and strong demands related to logistics, but also interesting productive reconversions, together with the consciousness of the complex interrelation through different sectors and their supply chain.
For SMEs, the introduction of new products has often meant a real revolution in the business, but able to ensure continuity in production that would otherwise have stopped. Moreover, in case the reconversions are expected to be permanent, are requiring new professional figures to support the activity.
And, most of all, the emergency confirmed the relevance of the human factor.
3. Concrete approaches to critical infrastructure protection
3.1 Supply chain continuity management and lack of manpower during the pandemic
Supply Chain Continuity Management (SCCM) must be considered as a necessary evolution of Business Continuity Management (BCM) models. SCCM is outlined in the ISO 22318 standard which is part of the group of standards for continuity management including ISO 22301, ISO 22313 Security and resilience (ISO 22318), and ISO 28000, which specifies the requirements for a security management system, including those aspects critical to security assurance of the supply chain. SCCM defines continuity in relation to external supplies, third parties or internal entities that play a supplier role in the context of the organization.
The simplified representation of the supply chain therefore provides a composite structure of internal and external suppliers (considering also the flexibility applicable to the relationships between the suppliers) that contribute to the operations of an organization and consequently of its customers.
If the relationship with suppliers is characterized by assets that are mainly intangible and movable and therefore related, for example, to the exchange of information or movable consumer goods, there will be greater control. An example in this sense, during the pandemic emergency management consisted in the possibility of maintaining relationships with suppliers through forms of smart working. This form of collaboration and coordination has been possible mainly between entities operating in sectors consisting of intangible assets such as professional, scientific and technical activities, financial and insurance activities, the activities of extraterritorial organizations, public administration and most professional services and, in general, all sectors that have not been affected by the suspension decrees.
In any case it will be necessary to have a management plan in case of crisis or incidents involving the supply chain.
The adoption of such measures will result in increasing control over the value chain in relation to an organization. In particular, the analysis carried out on the supply chain gives visibility to the mapping of interdependencies between different sectors allowing an analysis that goes beyond the single organization. Network analysis techniques could be combined with criticality and reliability metrics in order to produce composite methods that provide useful information to stakeholders [21].
As for ISO 22301, to plan the SCCM it will be necessary to carry out Impact Analysis activities with the individual suppliers involved, distinguishing critical suppliers from non-critical suppliers. For all relationships with critical suppliers, the guarantee of continuity can be determined by identifying a SCCM strategy to be agreed in transparency with these suppliers. Some strategic approaches may be:
Reducing dependence on a supplier: direct engagement of substitute suppliers for a specific service; increasing on-site stock holding; establishing alternative solutions.
Increasing resilience: loss mitigation; establishing mutual support policies with competitors.
Working with suppliers: creating partnerships with suppliers; setting performance standard; monitoring and dealing with suppliers to increase their resilience; including SCCM requirements in supplier contracts.
The direct effects of the suspension decrees concerned the sectors directly involved and all those sectors that had to sustain the labor shortage caused by the lockdown. While other sectors not directly involved in the suspension decrees, such as financial services or wholesale trade, or sectors more prone to targeted reconversions and the adoption of smart working strategies such as online trade or the fashion sector, were able to stem the direct impact of the emergency or even profit from it.
The Italian National Institute of Statistics in May 2020 has provided a wide range of data and information about the positioning and contribution of the sectors within the Italian production system.
The database is based on the Extended Statistical Register on Economic Performance of Enterprises (Frame-SBS), which contains individual data on all industrial and service enterprises active in the country (about 4.4 million units), supplemented with additional statistical registers that provide detailed information on the characteristics of the employment, as well as import and export enterprises. The data have been further integrated with indicators taken from Italian Accounting.
Considering the enterprises that are part of the universe of reference of the system of Structural Business Statistics (SBS), those that from May 4 are operating in sectors still formally suspended are about 800 thousand (19.1% of the total), with an employment weight of 15.7% on the total of the sectors of industry and market services (excluding the financial sector) [22].
By revising and analyzing the Istat dataset updated in May 2020 [23] with regard to the pandemic, it can be observed in the Figure 1 below that the unavailability of manpower has most directly affected the following sectors in percentage terms:
Other mining and quarrying activities; creative, artistic and entertainment activities; travel agency, tour operator and reservation services and related activities; libraries, archives, museums and other cultural activities; rental and operative leasing activities; real estate activities; activities concerning lotteries, betting, gambling houses; Sports, entertainment and leisure activities; construction of buildings; Mining of metal ores; Manufacture of other transport equipment; Manufacture of leather and related products; Manufacture of motor vehicles, trailers and semi-trailers; Manufacture of furniture; Tobacco industry; Metallurgy; Advertising and market research: 100%
Manufacture of clothing, manufacture of leather and fur articles: 98,48%
Manufacture of fabricated metal products (except machinery and equipment): 93,98%
Manufacture of other non-metallic mineral products: 92,85%
Food service activities: 90,91%
Manufacture of machinery and equipment NCA: 89,48%
Textile industries: 86,77%
Other personal service activities: 83,46%
Wholesale trade (except of motor vehicles and motorcycles): 67,23%
Manufacture of rubber and plastic products: 63,67%.
Figure 1.
Unavailability of manpower.
3.2 Approaches to supply chain what if analysis: dependencies trees
Considering the analyses and remediation plans structured to protect the SCC, it is possible to structure What If models oriented to predict the consequences linked to the lack of a supply.
In relation to the manpower issue, for example, it is possible to structure time-oriented models that consider the negative effects of the manpower.
The Domino Effect methodology applied to manpower aims to study and quantify the consequences of a negative event that causes a lack of personnel and/or supply chain. The model is configured as a visualization of the propagation over time of the negative effects caused by the unavailability of a certain percentage of company personnel.
Such a predictive model can allow the decision maker to simulate different crisis scenarios resulting from the loss of personnel based on the formal organizational structure of the company. In order for the model to be effective, however, it will be essential to feed the model and the collection of information starting from the analysis of the organizational chart and the company function chart.
Information is needed that can be traced back to the following organizational areas:
Administration (ADM)
Actors in charge of Crisis Management (CM)
Functions that have relationships with critical suppliers (SUP)
Business (BSS)
Commercial (COM).
The holistic evolution of this model consists in describing the interdependencies between different sectors starting from the simulation of a disservice concerning a sector. The generic example below can be applied to a single reality in order to understand what long-term effects the lack of manpower, considered as a distinguished sector, could have on the operational continuity of the organization itself (Figure 2).
Figure 2.
Manpower cascading effect on organizational areas.
The severity of the dependency corresponds to the extent to which the Quality of Service (QoS) perceived by the user is deteriorated. Depending on the item, the degradation can be measured by the variation of some specific parameters (coverage, signal reception, delivery time, etc.) with respect to the normal QoS values. In general, the measures that allow to characterize the QoS can be traced back to the general concepts of availability and capacity: the quality with which the service is provided can be described by quantifying the quantity of items provided in comparison to the demand and the time in which the service is actually available. The choice of the temporal moments in which to sample the phenomenon varies according to the item represented.
Metrics commonly agreed to in these cases include: Abandonment Rate; ASA (Average Speed to Answer); TSF (Time Service Factor); FCR (First-Call Resolution); TAT (Turn-Around Time); TRT (total resolution time); MTTR (Mean Time To Recover).
Starting from the elaboration of matrices that consider dependency relations, to represent a domino effect map it is necessary to apply a “filter” based on the degradation level of the service. an item will be considered compromised (and therefore will be represented in the domino effect map) only if the QoS degradation will be higher than a certain threshold, so the service is not considered acceptable (outage).
Various methods are described in the literature to perform this assessment. In general, the most common approaches consist in identifying some indicators that describe the various aspects of the consequences caused by an out of service event.
These indicators can fall into the following categories:
number of people (evaluated in terms of people impacted by the disruption)
economic damage (assessed in terms of the extent of economic losses and/or deterioration of products or services)
effects on public opinion (assessed in terms of impact on public confidence, physical suffering, and disruption of daily life).
Simulation of interdependencies and graph-based model to understand critical infrastructure interdependencies are proposed in literature [24, 25, 26, 27].
The graphical output here proposed (Figure 3) from the described model consists of dependency trees, time-oriented, that describe the collapse of the internal structure of an organization following the manpower “sector” unavailability. This model can be applied to a single organization based on its SC analysis starting considering one or more products and services sectors.
Figure 3.
Manpower dependency tree.
By re-analyzing the ISTAT indices and considering the main sectors activated by the sectors impacted by the manpower shortage, it is possible to identify which related sectors have been most impacted by service interruptions than those listed above.
The sectors impacted indirectly by the shortage of manpower compared with the interruptions of those impacted directly are as follows:
Rental and management of owned or leased properties
Legal and accounting activities
Road freight transport, removal and pipeline transport
Financial service activities (except insurance and pension funding)
Wholesale
Manufacture of fabricated metal products (except machinery and equipment)
As we can see in Figure 4, some sectors such as Financial Services Activities that did not undergo significant effects during the first phase of the lockdown, are subject to an indirect impact due to the activity suspension of their main suppliers.
Figure 4.
Index of indirect impact on SCC for other sectors not highly affected by unavailability of manpower.
3.3 Augustus method and its application by the Italian civil protection
The Augustus method can be considered as another concrete approaches to Critical Infrastructure protection.
The Method is a tool used by the Civil Protection Department of the Italian Republic for emergency planning. The Augustus Method was created in order to equip the Italian Civil Protection Service with a unified strategy for planning the Civil Protection assistance at various levels of competence.
This method is named after the Roman Emperor Augustus (27 B.C. to 14 A.D.), who affirmed that: “The value of planning decreases with the complexity of the state of things.” In detail, Augustus stated that it is impossible to plan a strategy in the smallest detail, because the event when it happens will always present in a different way. The Augustus Method is generated from the need to harmonize the directions of emergency planning.
This approach to the complexity of modern reality was structured and adapted by Elvezio Galanti, who considers the “emergency” (a public situation of particular difficulty and danger) an “organism” with its own life and composed by physiological functions (endocrine system, cardiology, etc.), each one specialized in its own field in which normally carries out its ordinary activity. In the context of civil protection, the “organism” is defined as the territory in which they normally act, and each one because of its specific functions (municipal, regional, health, transport, etc.). In the event of a disaster, these activities must all work together and in synergy.
The Augustus Methodology highlights, therefore, a fundamental aspect of the functioning of the Italian Civil Protection: its systemic nature. A complex apparatus made up of different elements and different organizations, resulting from the functioning of different systems in interaction with each other and with the other organizational systems [28].
In the preventive design phase, the Civil Protection, first of all, must work to collect information (time of occurrence of an event, geological conformation, productive fabric, urban fabric, etc.), then it must proceed with basic examinations (hazard analysis, vulnerability analysis, etc.) and finally a first diagnosis will be made (scenario, i.e. what I expect to happen) and for this reason, facilities will be arranged (monitoring networks, cleaning of riverbeds, seismic adaptation of structures, etc.).
In the absence or in the impossibility of activating these protocols, minimum measures of confrontation will be taken through the constitution of a “resilient cell” to manage the “big 5”, i.e. five macro-areas in which the operational approach is divided into “acute emergency”. These are:
identification of sites per control room;
entry points for expected rescue;
reception areas and first assistance to the population;
identification of proximity sites to coordinate local interventions;
assistance to the population (health and management of any temporary camps for reception and stay).
In the “acute” emergency scenario the Augustus Method becomes a good practice to manage the situation through the identification of 14 basic support functions, or support, that match all the competent and specific institutional figures for each function at territorial level and that contribute to its ordinary and extraordinary functioning. These functions are usually involved during the emergency itself, while in the study phases prior to the emergency, such as forecasting and prevention, they are deactivated and delivered to their specific and ordinary institutional functioning. These functions are: F 1 - Technology and planning; F 2 - Health, social and veterinary assistance; F 3 - Mass-media and information; F 4 - Volunteering; F 5 - Materials and means; F 6 - Transport, traffic and roads; F 7 - Telecommunications; F 8 - Essential services; F 9 - Census of damage to persons and property; F 10 - Operational facilities; F 11 - Local authorities; F 12 - Hazardous materials; F 13 - Assistance to the population; F 14 - Coordination of operational centres.
The design of all coordinated activities and procedures of Civil Protection to respond to any disaster event that is expected in a specific territory is called “Emergency Plan”. The Emergency Plan must be implemented:
Forecasting and Prevention Programs
Information related to:
physical processes causing the risk conditions and their assessments
precursors
events
scenarios
available resources.
Therefore, it is necessary to represent graphically the information necessary for the characterization of possible risk scenarios for the implementation of intervention strategies for the rescue and management of the emergency, rationalizing and targeting the use of men and means.
According to the Method, the following conditions determine the success of a civil protection operation [29]:
unitary direction: the unitary direction of emergency operations is implemented through the coordination of a complex system and not in a sectoral vision of the intervention.
communication: constant exchange of information between the central and peripheral Civil Protection system.
resources: rational and timely use of the resources really available and the availability of the men and means suitable for intervention.
The Emergency Plan structured according to the Augustus Method must be able to answer the following questions:
what calamitous events may reasonably affect the municipality?
which people, facilities and services will be affected or damaged?
what operational organization is necessary to minimize the effects of the event with particular attention to the protection of human life?
to whom are the different responsibilities at the various levels of command and control for emergency management assigned?
To satisfy these needs, it is first of all necessary to define the risk scenarios on the basis of the vulnerability of the portion of the territory concerned (areas, population involved, damaged structures, etc.) in order to have a global and reliable picture of the expected event and therefore to be able to dimension in advance the operational response necessary to overcome the disaster with particular attention to the protection of human life (how many firefighters, how many volunteers, which command and control structures, which roads or escape routes, which shelter structures, health areas, etc.).
The Emergency Plan is therefore a working tool calibrated on a likely situation based on scientific knowledge of the state of risk of the territory, which can be updated and integrated with reference to the list of men and means, but especially when new knowledge is acquired on the conditions of risk involving different assessments of the scenarios, or even when new or additional monitoring and warning systems to the population are available [30].
On the provincial level, the Emergency Plan will identify, at an inter-municipal or provincial scale: on the one side the situations that can configure a more extensive emergency of the single municipality, on the other side the situations, even localized, of greater risk, pointing out, when necessary, the need for an in-depth study of some aspects related to the Municipal scale.
On municipal level, a more detailed level of information is needed to allow the operators of the various components of the Civil Protection to have a reference framework corresponding to the size of the expected event, the population involved, the alternative road system, possible escape routes, waiting areas, shelter, storage areas and so on. Considering that the risk present in a given territory may refer to different types of events (floods, earthquakes, landslides, etc.), the Emergency Plan must provide for one or more “risk scenarios”, which must or may correspond to different types of intervention.
The Italian Civil Protection assumes primary and decisive roles on the institutional scene of civil protection in Italy. This body sums up three fundamental structures at national level:
the Civil Protection Department at the Presidency of the Council of Ministers
the General Directorate of Civil Protection and Firefighting Services at the Ministry of the Interior
the National Seismic Service at the Department of National Technical Services (currently dependent on the Ministry of Public Works).
The Civil Protection plays a key role in the management of national emergencies but not only: the possibility of being activated by the Prefect (Prefetto) for emergencies and in particular cases also for events at local level, makes the Civil Protection an entity that can operate de facto across the board. The Prefect is the cornerstone of the command and coordination structure of the civil protection operational system.
Another key player is represented by the Mayor. He is the determining element in the operational chain of civil protection at municipal level in the assumption of all responsibilities related to civil protection tasks: from the preventive organization of control and monitoring activities to the adoption of emergency measures aimed primarily at safeguarding human life.
It is appropriate, at this point, to make one final consideration: the Emergency Plan is drawn up in any case on the basis of the scientific knowledge possessed at the time of writing, without waiting for studies in progress or future assignments or improvements. An “expeditious” plan, even if imprecise and precautionary, is better than no plan at all. As soon as possible, the Emergency Plan will be reviewed, improved, and completed with more data and more scientific bases.
The key concept of contingency planning is to try to predict all possible variables, however, it is necessary to be aware that it will always be possible, in any emergency, to face something unforeseen.
3.4 The Italian civil protection strategy for the management of the 2020 crisis
The coordination of the members of the National Service of Civil Protection is happening according to the provisions of the Augustus Method thanks to the synchronism of the representatives of each operational function (Health, Volunteering, Telecommunications, etc..) to interact directly with each other.
The intervention model adopted by civil protection for the management of the epidemiological emergency [31] based on the definition of the chain of command and control, the communication flow and the procedures to be activated in relation to the emergency state determined by the spread of the pandemic.
The chain of command and control includes the following levels of coordination:
National level: the Head of the Civil Protection Department ensures the coordination of the necessary interventions, making use of the Department, the components, and operational structures of the National Civil Protection Service, as well as implementing entities. At the Department of Civil Protection is active the Civil Protection Operational Committee, with the task of ensuring the contribution and support of the National Civil Protection System on the basis of the health indications defined by the Ministry of Health, which makes use of the ISS (Istituto Superiore Sanità) and the Scientific Technical Committee specifically established with the OCDPC 630/2020 at the Department.
Regional level: at all Regions must be activated a regional crisis unit, which operates in close connection with the SOR - Regional Operations Room, which must provide for the participation of the Regional Health Contact, which operates in connection with the Health Director of the local health agencies, and in constant contact with a representative of the Chief Prefecture, in order to ensure the connection with the other Prefectures - UTG of the regional territory.
Provincial level: in the provinces in which at least one person is positive for whom the source of transmission is unknown or in any case where there is a case not attributable to a person from an area already affected by the virus, as provided by art. 1, paragraph 1 of Decree-Law no. 6 of 23.02.2020, the Prefect or his delegate provides for the activation of the CCS - Rescue Coordination Centre
Municipal level: in the municipalities or areas in which at least one person is positive for whom the source of transmission is unknown or in any case where there is a case not attributable to a person from an area already affected by the aforementioned virus, as provided by art. 1 paragraph 1 of Decree-Law no. 6 of 23.02.2020, the Mayor or his delegate provides for the activation of the Municipal Operations Centre - COC of the municipality involved and neighboring municipalities in order to implement possible preventive actions.
Therefore, in order to cope with the pandemic and in accordance with the provisions of the Augustus Method, collaborative decision-making processes have been initiated in real time in the operational rooms of the various levels such as:
Centro Coordinamento dei Soccorsi (CCS) - Rescue Coordination Centre
Centro Operativo Comunale (COC) - Municipal Operations Centre
Centro Operativo Misto (COM) - Mixed Operations Centre.
The CCS is the main body at provincial level and is chaired by the Prefect or his delegate. By COC is meant the Municipal Operations Centre, responsible for the activities at municipal-local level, whose maximum point of reference is the Mayor or his delegate (Law 225/1992 - Art. 15). Finally, the COM is the Mixed Operations Centre. They can be more than one and set up ad hoc to be as close as possible to the place of the event.
Originally established as emergency operational centres (i.e. support and operational coordination structures set up and organized exclusively in the full management phase of the emergency following catastrophic events), over time the term has moved to a broader interpretation of the term which also involves structures and organizational divisions of one or more local administrations in the construction of the local civil protection system as well as emergency planning activities to be carried out in ordinary time.
In this emergency caused by the pandemic, a key role is played by the COC, which have been activated in many Italian municipalities [32].
Specifically, the Mayor makes use of the COC to ensure the direction and coordination of rescue and assistance services to the population within his municipal territory in relation to the declaration of the state of emergency issued by the Italian Government. The choice of the location of this Centre must be in earthquake-proof structures, in areas with easy access and not vulnerable to any kind of risk. These facilities must be equipped with a square of enough size to accommodate heavy vehicles and anything else needed in a state of emergency. The COC is responsible for the decision-making levels of the entire municipal structure, summarized in the trade union responsibilities referred to in the previous paragraphs; as a rule, the decision-making level is taken by the Mayor who, through a municipal civil protection system, identifies the actions and strategies necessary to try to keep the infection curve and morbidity index under control. The COC operates in a place of coordination called “operations room” where all the news related to the event converge and where decisions are taken to overcome it. In many municipalities, the COC has been activated by the Mayor as an immediate consequence of the increase in infections within the national territory, and not necessarily in the municipal one, and it will remain operational until the resolution of the pandemic crisis [33].
According to the Civil Protection Operational Measures for the management of the epidemiological emergency [31] actions and operational measures identified for each level of coordination, without prejudice to the provisions issued by the Ministry of Health, are as follows:
information to the population
activation of local volunteering, in connection with the levels of coordination above
organization of actions at the municipal level, in connection with the regional and provincial level, actions to ensure the continuity of essential services, as well as the collection of waste in areas affected, or that may be affected, by urgent measures of containment
organization of actions at the municipal level, in connection with what has been prepared at the regional level, actions aimed at ensuring the continuity of the supply of basic necessities (including fuel supplies) in the areas concerned, or that could be affected by urgent containment measures;
planning, or possible activation, of the actions of assistance to the population of the municipalities concerned, or that could be affected by urgent containment measures
planning and organization of home care services for persons in home quarantine (e.g., basic necessities, medicines, pre-packaged meals…), possibly carried out by personnel of volunteer organizations, appropriately trained.
At this point, it can be stated that the success of a civil protection operation can be achieved if three parameters are satisfied: coordination, communication, and resource management.
4. Conclusion
As with any crisis management strategy, resilience strategies must be planned and prepared during the “peace” period and then implemented, appropriately adapted, during crisis situations. The variable structure, and a proactive response, is what succeeds in giving us a continuity and dealing successfully with the complexity.
Labor shortages directly affected all those sectors that had to close due to the impossibility to convert their business using smart working. Some activities, although part of sectors not directly involved in the lockdown, were indirectly affected by labor shortages caused by the inability of seasonal and commuting staff to move. Finally, the indirect repercussions that have affected those activities that, while remaining operational, have suffered significant economic repercussions due to the interruption of their supply chain caused by the shortage of labor in other sectors.
To be considered in the degree of dependence that an organization might have on its suppliers, beyond its intrinsic resilience, is the degree of flexibility applicable to relations with the various suppliers.
To plan the SCCM it will be necessary to carry out Impact Analysis activities with the individual suppliers involved, distinguishing critical suppliers from non-critical suppliers. For all relationships with critical suppliers continuity can be determined by identifying a SCCM strategy to be agreed transparently with these suppliers. Some strategic approaches may be:
Reducing dependence on a supplier: direct engagement of alternative suppliers for a given service; increasing on-site stock holding; establishing alternative solutions.
Increased resilience: mitigation of losses; identification of a set of alternative suppliers; establishing mutual support policies with competitors.
Working with suppliers: creating partnerships with suppliers; setting performance standards (including through SLAs); monitoring and dealing with suppliers to increase their resilience; including SCCM requirements in supplier contracts.
The adoption of these measures will result in increasing control over the value chain in relation to an organization. In particular, the analysis carried out on the supplier chain gives visibility to the mapping of the interdependencies between the different sectors enabling an analysis that goes beyond the single organization.
Therefore, maximum flexibility and, at the same time, the ability to create the preconditions (e.g. through exercises) is needed to ensure that the best conditions for success are in place in these cases as well.
Moreover, most of all, the 2020 crisis confirmed the relevance of the human factor.
The Italian case is an example of how the set of private initiatives, the support of adequate policies of incentives and support from the State, together with a strong sense of solidarity with the population, can represent a positive reaction to a negative event, and that business strategies oriented towards business continuity are the basis for the development of resilience in the productive sector, and the resilience of the Critical Infrastructures.
\n',keywords:"complex system, emergency management, manpower, cascading effects, resilience",chapterPDFUrl:"https://cdn.intechopen.com/pdfs/74141.pdf",chapterXML:"https://mts.intechopen.com/source/xml/74141.xml",downloadPdfUrl:"/chapter/pdf-download/74141",previewPdfUrl:"/chapter/pdf-preview/74141",totalDownloads:319,totalViews:0,totalCrossrefCites:0,totalDimensionsCites:0,totalAltmetricsMentions:0,impactScore:0,impactScorePercentile:40,impactScoreQuartile:2,hasAltmetrics:0,dateSubmitted:"June 29th 2020",dateReviewed:"November 3rd 2020",datePrePublished:"November 21st 2020",datePublished:"July 7th 2021",dateFinished:"November 21st 2020",readingETA:"0",abstract:"Approaches to risk analysis, crisis management and resilience enhancement for Critical Infrastructure (CI) Protection will be considered starting from a case study related to the management of the pandemic in Italy. Business continuity and crisis management models for CI are analyzed aiming to deal with complexity and reduce uncertainty relating pandemic and long-time crisis. Furthermore, is presented a methodology highlighting the functioning of the Italian Civil Protection and its systemic nature: a complex apparatus made up of different elements and organizations, which derives from the functioning of different organizational systems in interaction with each other. As a baseline for the coordination management the Augustus Method is considered for its strategical, tactical and operational aspects. One of the main outputs of the research consists in creating a “what if” forecasting model, configured as a visualization of the propagation of negative effects on the supply chain and manpower over time.",reviewType:"peer-reviewed",bibtexUrl:"/chapter/bibtex/74141",risUrl:"/chapter/ris/74141",book:{id:"10256",slug:"issues-on-risk-analysis-for-critical-infrastructure-protection"},signatures:"Luisa Franchina, Alessandro Calabrese, Enrico Scatto and Giulia Inzerilli",authors:[{id:"325804",title:"Ph.D.",name:"luisa",middleName:null,surname:"franchina",fullName:"luisa franchina",slug:"luisa-franchina",email:"blustarcacina@gmail.com",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:null},{id:"326318",title:"Dr.",name:"Alessandro",middleName:null,surname:"Calabrese",fullName:"Alessandro Calabrese",slug:"alessandro-calabrese",email:"a.calabrese@hermesbay.com",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:null},{id:"326319",title:"Dr.",name:"Giulia",middleName:null,surname:"Inzerilli",fullName:"Giulia Inzerilli",slug:"giulia-inzerilli",email:"g.inzerilli@hermesbay.com",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:null},{id:"326320",title:"Dr.",name:"Enrico",middleName:null,surname:"Scatto",fullName:"Enrico Scatto",slug:"enrico-scatto",email:"e.scatto@hermesbay.com",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:null}],sections:[{id:"sec_1",title:"1. Introduction",level:"1"},{id:"sec_2",title:"2. Addressing complexity and impacts of pandemic in critical infrastructure",level:"1"},{id:"sec_2_2",title:"2.1 The Italian production strategy during the 2020 pandemic: statal measures and production conversion",level:"2"},{id:"sec_4",title:"3. Concrete approaches to critical infrastructure protection",level:"1"},{id:"sec_4_2",title:"3.1 Supply chain continuity management and lack of manpower during the pandemic",level:"2"},{id:"sec_5_2",title:"3.2 Approaches to supply chain what if analysis: dependencies trees",level:"2"},{id:"sec_6_2",title:"3.3 Augustus method and its application by the Italian civil protection",level:"2"},{id:"sec_7_2",title:"3.4 The Italian civil protection strategy for the management of the 2020 crisis",level:"2"},{id:"sec_9",title:"4. Conclusion",level:"1"}],chapterReferences:[{id:"B1",body:'P. Hokstad, I. Utne, I. Vatn; Risk and Interdependencies in Critical Infrastructures: A Guideline for Analysis; Springer; 2012'},{id:"B2",body:'Y. Deng, L. song, Z. Zhou, P. Liu; Complexity and Vulnerability Analysis of Critical Infrastructures: A Methodological Approach; Mathematical Problems in Engineering. 2017'},{id:"B3",body:'M. Tvaronaviciene; Towards internationally tuned approach towards critical infrastructure protection; Journal of Security and Sustainability Issues; 2018'},{id:"B4",body:'Gorzeń-Mitka, M. Okręglicka; Managing Complexity: A Discussion of Current Strategies and Approaches; Procedia Economics and Finance. 27. 438-444; 2015'},{id:"B5",body:'I. Sperstad, G. Kjølle, O. Gjerde; A Comprehensive Framework for Vulnerability Analysis of Extraordinary Events in Power Systems; Reliability Engineering; 2019'},{id:"B6",body:'R. Napoli; Coronavirus e infrastruttura elettrica; AIIC Newsletter no. 06/2020'},{id:"B7",body:'R. Setola; La sicurezza nazionale alla prova della resilienza. L’analisi di Setola; Formiche, 1st April 2020'},{id:"B8",body:'Principi Precauzionali Per Gli Operatori Di Infrastrutture Critiche ai fini della continuità in sicurezza del servizio di interesse pubblico; Ufficio del Consigliere Militare, Segreteria Infrastrutture Critiche; 26th March 2020'},{id:"B9",body:'COVID-19: assicurata la piena funzionalità del Centro di Controllo Galileo al Fucino; Telespazio, 29th April 2020'},{id:"B10",body:'Chiappetta; Italia next ovvero un decalogo per il dopo Coronavirus. Intervento di Chiappetta; Formiche, 5th April 2020'},{id:"B11",body:'E. Luiijf, A. Nieuwenhuijs, M. Klaver, M. Eeten, E. Cruz; Empirical findings on European critical infrastructure dependencies; International Journal of System of Systems Engineering; 2. 3. 10.1504/IJSSE.2010.035378; 2010'},{id:"B12",body:'G. Pisano, R. Sadun, M. Zanini; Lessons from Italy’s Response to Coronavirus; Harvard Business Review; 27th March 2020'},{id:"B13",body:'Decreto Presidente del Consiglio dei Ministri 4th May 2020'},{id:"B14",body:'Emergenza Covid, oltre 3 mila ventilatori polmonari dalla sinergia tra Fca e Siare, la Repubblica; 9th July, 2020'},{id:"B15",body:'È genovese, il brevetto che converte le maschere da sub in protezioni contro la Covid-19; Il Secolo XIX; 24th March, 2020'},{id:"B16",body:'A. Carli; Mascherine e respiratori, ecco le fabbriche che si riconvertono; il Sole 24 Ore, 24th March, 2020'},{id:"B17",body:'P. di Lazzaro; Le mascherine della ex Mabro; Rainews; 17th March 2020'},{id:"B18",body:'A. Nasso; Coronavirus, Roncato ferma produzione valigie: “Facciamo mascherine, nel nostro futuro anche guanti e visiere”; la Repubblica; 28th April, 2020'},{id:"B19",body:'European Commission Press Release; State aid: Commission approves €50 million Italian support scheme for production and supply of medical equipment and masks during Coronavirus outbreak; 22nd March 2020'},{id:"B20",body:'Newsroom; Face masks, sanitiser gel and ventilators – those Italian factories switching their production; Mornong Future; 4th May 2020'},{id:"B21",body:'J. Williams; Critical Flow Centrality Measures on Interdependent Networks with Time-Varying Demands; University of Toronto, Department of Computer Science, Canada; 2019'},{id:"B22",body:'ISTAT; Dataset contributo e posizionamento dei settori produttivi; 12nd May 2020; Available from: https://www.istat.it/it/archivio/239854'},{id:"B23",body:'ISTAT; Nota esplicativa situazione 4 maggio; 11st May 2020; Available from: https://www.istat.it/it/files//2020/04/nota-esplicativa_situazione_04maggio.pdf'},{id:"B24",body:'N. Svendsen, S. Wolthusen; Graph Models of Critical Infrastructure Interdependencies; First International Conference on Autonomous Infrastructure, Management and Security, AIMS 2007'},{id:"B25",body:'S. Dominique, Y. Barbarin, M. Eid; Preparing for the Domino Effect in Crisis Situation D2.1 State of the Art of the R&D Activities in Cascade Effect & Resilience and Global Modelling; Report PREDICT-20151217-D2-1V3; 2018'},{id:"B26",body:'O. Pala, P. Schrum; Simulating Infrastructure Outages: An Open-Source Geospatial Approach; Conference: GeoInformation for Disaster ManagementAt: Istanbul Technical University; 2018'},{id:"B27",body:'A. Rahman, Ḥāfiẓ; Modelling and simulation of interdependencies between the communication and information technology infrastructure and other critical infrastructures; 2009'},{id:"B28",body:'E. Galanti; Il Metodo Augustus; DPC INFORMA “Periodico informativo del Dipartimento della Protezione Civile” (year II; number 4); 1997'},{id:"B29",body:'Presidency of the Council of Ministers, Italian Civil Protection Department; National Risk Assessment; December 2018'},{id:"B30",body:'Provicial Emergency Plan; Metodo Augustus e Funzioni di Supporto; Assessorato alla Protezione Civile; 2008'},{id:"B31",body:'Dipartimento di Protezione Civile; Misure operative di protezione civile per la gestione dell’emergenza epidemiologica da Covid-19; 4th May 2020'},{id:"B32",body:'Comune di Olevano sul Tusciano; Istituzione del “Centro Operativo Comunale (COC)” per l’emergenza di protezione civile COVID-19, 23rd March 2020; https://www.comune.bergamo.it/node/188215'},{id:"B33",body:'Emergenza Coronavirus Covid-19 Sul Territorio Nazionale – Attivazione C.O.C. 8th March 2020, https://www.olevanosultusciano.gov.it/avvisi/emergenza-coronavirus-covid-19-sul-territorio-nazionale-attivazione-c-o-c-centro-operativo-comunale/'}],footnotes:[],contributors:[{corresp:null,contributorFullName:"Luisa Franchina",address:null,affiliation:'
'}],corrections:null},book:{id:"10256",type:"book",title:"Issues on Risk Analysis for Critical Infrastructure Protection",subtitle:null,fullTitle:"Issues on Risk Analysis for Critical Infrastructure Protection",slug:"issues-on-risk-analysis-for-critical-infrastructure-protection",publishedDate:"July 7th 2021",bookSignature:"Vittorio Rosato and Antonio Di Pietro",coverURL:"https://cdn.intechopen.com/books/images_new/10256.jpg",licenceType:"CC BY 3.0",editedByType:"Edited by",isbn:"978-1-83962-621-0",printIsbn:"978-1-83962-620-3",pdfIsbn:"978-1-83962-628-9",reviewType:"peer-reviewed",numberOfWosCitations:1,isAvailableForWebshopOrdering:!0,editors:[{id:"27002",title:"Dr.",name:"Vittorio",middleName:null,surname:"Rosato",slug:"vittorio-rosato",fullName:"Vittorio Rosato"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,coeditorOne:{id:"284589",title:"Dr.",name:"Antonio",middleName:null,surname:"Di Pietro",slug:"antonio-di-pietro",fullName:"Antonio Di Pietro"},coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"861"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"},chapters:[{id:"74123",type:"chapter",title:"Resilience in Critical Infrastructures: The Role of Modelling and Simulation",slug:"resilience-in-critical-infrastructures-the-role-of-modelling-and-simulation",totalDownloads:342,totalCrossrefCites:0,signatures:"Chiara Foglietta and Stefano Panzieri",reviewType:"peer-reviewed",authors:[{id:"325843",title:"Assistant Prof.",name:"Chiara",middleName:null,surname:"Foglietta",fullName:"Chiara Foglietta",slug:"chiara-foglietta"},{id:"325858",title:"Prof.",name:"Stefano",middleName:null,surname:"Panzieri",fullName:"Stefano Panzieri",slug:"stefano-panzieri"}]},{id:"74122",type:"chapter",title:"Risk Analysis in Early Phase of Complex Infrastructure Projects",slug:"risk-analysis-in-early-phase-of-complex-infrastructure-projects",totalDownloads:318,totalCrossrefCites:0,signatures:"Esra Tepeli",reviewType:"peer-reviewed",authors:[{id:"325453",title:"Dr.",name:"Esra",middleName:null,surname:"Tepeli",fullName:"Esra Tepeli",slug:"esra-tepeli"}]},{id:"74143",type:"chapter",title:"Resilience of Critical Infrastructures: A Risk Assessment Methodology for Energy Corridors",slug:"resilience-of-critical-infrastructures-a-risk-assessment-methodology-for-energy-corridors",totalDownloads:324,totalCrossrefCites:0,signatures:"Andrea Carpignano, Daniele Grosso, Raffaella Gerboni and Andrea Bologna",reviewType:"peer-reviewed",authors:[{id:"119419",title:"Prof.",name:"Andrea",middleName:null,surname:"Carpignano",fullName:"Andrea Carpignano",slug:"andrea-carpignano"},{id:"325945",title:"Dr.",name:"Raffaella",middleName:null,surname:"Gerboni",fullName:"Raffaella Gerboni",slug:"raffaella-gerboni"},{id:"325947",title:"Dr.",name:"Daniele",middleName:null,surname:"Grosso",fullName:"Daniele Grosso",slug:"daniele-grosso"},{id:"325948",title:"MSc.",name:"Andrea",middleName:null,surname:"Bologna",fullName:"Andrea Bologna",slug:"andrea-bologna"}]},{id:"76951",type:"chapter",title:"Resilience and Situational Awareness in Critical Infrastructure Protection: An Indicator-Based Approach",slug:"resilience-and-situational-awareness-in-critical-infrastructure-protection-an-indicator-based-approa",totalDownloads:306,totalCrossrefCites:0,signatures:"Aleksandar S. Jovanovic, Somik Chakravarty and Marjan Jelic",reviewType:"peer-reviewed",authors:[{id:"325342",title:"Prof.",name:"Aleksandar S.",middleName:null,surname:"Jovanovic",fullName:"Aleksandar S. Jovanovic",slug:"aleksandar-s.-jovanovic"},{id:"336286",title:"Mr.",name:"Marjan",middleName:null,surname:"Jelic",fullName:"Marjan Jelic",slug:"marjan-jelic"},{id:"336287",title:"Dr.",name:"Somik",middleName:null,surname:"Chakravarty",fullName:"Somik Chakravarty",slug:"somik-chakravarty"}]},{id:"76927",type:"chapter",title:"Integrating Resilience in Time-based Dependency Analysis: A Large-Scale Case Study for Urban Critical Infrastructures",slug:"integrating-resilience-in-time-based-dependency-analysis-a-large-scale-case-study-for-urban-critical",totalDownloads:214,totalCrossrefCites:2,signatures:"Vittorio Rosato, Antonio Di Pietro, Panayiotis Kotzanikolaou, George Stergiopoulos and Giulio Smedile",reviewType:"peer-reviewed",authors:[{id:"27002",title:"Dr.",name:"Vittorio",middleName:null,surname:"Rosato",fullName:"Vittorio Rosato",slug:"vittorio-rosato"},{id:"284589",title:"Dr.",name:"Antonio",middleName:null,surname:"Di Pietro",fullName:"Antonio Di Pietro",slug:"antonio-di-pietro"},{id:"326117",title:"Dr.",name:"Yiorgos",middleName:null,surname:"Stergiopoulos",fullName:"Yiorgos Stergiopoulos",slug:"yiorgos-stergiopoulos"},{id:"326118",title:"Dr.",name:"Giulio",middleName:null,surname:"Smedile",fullName:"Giulio Smedile",slug:"giulio-smedile"},{id:"326119",title:"Associate Prof.",name:"Kotzanikolaou",middleName:null,surname:"Panagiotis",fullName:"Kotzanikolaou Panagiotis",slug:"kotzanikolaou-panagiotis"}]},{id:"74668",type:"chapter",title:"A Strategy to Improve Infrastructure Survivability via Prioritizing Critical Nodes Protection",slug:"a-strategy-to-improve-infrastructure-survivability-via-prioritizing-critical-nodes-protection",totalDownloads:246,totalCrossrefCites:0,signatures:"Luca Faramondi, Giacomo Assenza, Gabriele Oliva, Ernesto Del Prete, Fabio Pera and Roberto Setola",reviewType:"peer-reviewed",authors:[{id:"326327",title:"Prof.",name:"Gabriele",middleName:null,surname:"Oliva",fullName:"Gabriele Oliva",slug:"gabriele-oliva"},{id:"326328",title:"Dr.",name:"Giacomo",middleName:null,surname:"Assenza",fullName:"Giacomo Assenza",slug:"giacomo-assenza"},{id:"326329",title:"Dr.",name:"Luca",middleName:null,surname:"Faramondi",fullName:"Luca Faramondi",slug:"luca-faramondi"},{id:"326330",title:"Prof.",name:"Roberto",middleName:null,surname:"Setola",fullName:"Roberto Setola",slug:"roberto-setola"},{id:"332852",title:"Dr.",name:"Ernesto",middleName:null,surname:"Del Prete",fullName:"Ernesto Del Prete",slug:"ernesto-del-prete"},{id:"332853",title:"Dr.",name:"Fabio",middleName:null,surname:"Pera",fullName:"Fabio Pera",slug:"fabio-pera"}]},{id:"73984",type:"chapter",title:"Validation Strategy as a Part of the European Gas Network Protection",slug:"validation-strategy-as-a-part-of-the-european-gas-network-protection",totalDownloads:262,totalCrossrefCites:0,signatures:"David Rehak, Martin Hromada, Ilias Gkotsis, Anna Gazi, Evita Agrafioti, Anastasia Chalkidou, Karolina Jurkiewicz, Fabio Bolletta and Clemente Fuggini",reviewType:"peer-reviewed",authors:[{id:"208287",title:"Prof.",name:"David",middleName:null,surname:"Rehak",fullName:"David Rehak",slug:"david-rehak"},{id:"240637",title:"Prof.",name:"Martin",middleName:null,surname:"Hromada",fullName:"Martin Hromada",slug:"martin-hromada"},{id:"326224",title:"M.Sc.",name:"Ilias",middleName:null,surname:"Gkotsis",fullName:"Ilias Gkotsis",slug:"ilias-gkotsis"},{id:"326225",title:"Dr.",name:"Anna",middleName:null,surname:"Gazi",fullName:"Anna Gazi",slug:"anna-gazi"},{id:"326227",title:"Dr.",name:"Evita",middleName:null,surname:"Agrafioti",fullName:"Evita Agrafioti",slug:"evita-agrafioti"},{id:"326228",title:"Dr.",name:"Anastasia",middleName:null,surname:"Chalkidou",fullName:"Anastasia Chalkidou",slug:"anastasia-chalkidou"},{id:"326229",title:"Dr.",name:"Fabio",middleName:null,surname:"Bolletta",fullName:"Fabio Bolletta",slug:"fabio-bolletta"},{id:"326230",title:"Dr.",name:"Clemente",middleName:null,surname:"Fuggini",fullName:"Clemente Fuggini",slug:"clemente-fuggini"},{id:"326819",title:"MSc.",name:"Karolina",middleName:null,surname:"Jurkiewicz",fullName:"Karolina Jurkiewicz",slug:"karolina-jurkiewicz"}]},{id:"74174",type:"chapter",title:"Defects Assessment in Subsea Pipelines by Risk Criteria",slug:"defects-assessment-in-subsea-pipelines-by-risk-criteria",totalDownloads:295,totalCrossrefCites:0,signatures:"Anatoly Lepikhin, Victor Leschenko and Nikolay Makhutov",reviewType:"peer-reviewed",authors:[{id:"231405",title:"Prof.",name:"Anatoly",middleName:null,surname:"Lepikhin",fullName:"Anatoly Lepikhin",slug:"anatoly-lepikhin"},{id:"327433",title:"Dr.",name:"Victor",middleName:null,surname:"Leschenko",fullName:"Victor Leschenko",slug:"victor-leschenko"},{id:"327435",title:"Prof.",name:"Nikolay",middleName:null,surname:"Machutov",fullName:"Nikolay Machutov",slug:"nikolay-machutov"}]},{id:"74240",type:"chapter",title:"Analyzing the Cyber Risk in Critical Infrastructures",slug:"analyzing-the-cyber-risk-in-critical-infrastructures",totalDownloads:341,totalCrossrefCites:2,signatures:"Marieke Klaver and Eric Luiijf",reviewType:"peer-reviewed",authors:[{id:"325818",title:"Dr.",name:"Marieke",middleName:null,surname:"Klaver",fullName:"Marieke Klaver",slug:"marieke-klaver"},{id:"325822",title:"MSc.",name:"Eric",middleName:null,surname:"Luiijf",fullName:"Eric Luiijf",slug:"eric-luiijf"}]},{id:"74493",type:"chapter",title:"Flood Risk Analysis for Critical Infrastructure Protection: Issues and Opportunities in Less Developed Societies",slug:"flood-risk-analysis-for-critical-infrastructure-protection-issues-and-opportunities-in-less-develope",totalDownloads:278,totalCrossrefCites:0,signatures:"Ugonna C. Nkwunonwo",reviewType:"peer-reviewed",authors:[{id:"314432",title:"Dr.",name:"Ugonna",middleName:null,surname:"Nkwunonwo",fullName:"Ugonna Nkwunonwo",slug:"ugonna-nkwunonwo"}]},{id:"76796",type:"chapter",title:"The Cultural Differences in the Perception and Application of Crisis Management in Tourism",slug:"the-cultural-differences-in-the-perception-and-application-of-crisis-management-in-tourism",totalDownloads:192,totalCrossrefCites:0,signatures:"Marica Mazurek",reviewType:"peer-reviewed",authors:[{id:"356479",title:"Dr.",name:"Marica",middleName:null,surname:"Mazurek",fullName:"Marica Mazurek",slug:"marica-mazurek"}]},{id:"74141",type:"chapter",title:"Italian Crisis Management in 2020",slug:"italian-crisis-management-in-2020",totalDownloads:319,totalCrossrefCites:0,signatures:"Luisa Franchina, Alessandro Calabrese, Enrico Scatto and Giulia Inzerilli",reviewType:"peer-reviewed",authors:[{id:"325804",title:"Ph.D.",name:"luisa",middleName:null,surname:"franchina",fullName:"luisa franchina",slug:"luisa-franchina"},{id:"326318",title:"Dr.",name:"Alessandro",middleName:null,surname:"Calabrese",fullName:"Alessandro Calabrese",slug:"alessandro-calabrese"},{id:"326319",title:"Dr.",name:"Giulia",middleName:null,surname:"Inzerilli",fullName:"Giulia Inzerilli",slug:"giulia-inzerilli"},{id:"326320",title:"Dr.",name:"Enrico",middleName:null,surname:"Scatto",fullName:"Enrico Scatto",slug:"enrico-scatto"}]}]},relatedBooks:[{type:"book",id:"7573",title:"Perspectives on Risk, Assessment and Management Paradigms",subtitle:null,isOpenForSubmission:!1,hash:"799ce26efc776b46b7b9f3aedff16edc",slug:"perspectives-on-risk-assessment-and-management-paradigms",bookSignature:"Ali G. Hessami",coverURL:"https://cdn.intechopen.com/books/images_new/7573.jpg",editedByType:"Edited by",editors:[{id:"108303",title:"Prof.",name:"Ali G.",surname:"Hessami",slug:"ali-g.-hessami",fullName:"Ali G. Hessami"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"},chapters:[{id:"66146",title:"Introductory Chapter: A Systems Framework for Risk Assessment",slug:"introductory-chapter-a-systems-framework-for-risk-assessment",signatures:"Ali Hessami",authors:[{id:"108303",title:"Prof.",name:"Ali G.",middleName:null,surname:"Hessami",fullName:"Ali G. Hessami",slug:"ali-g.-hessami"}]},{id:"63163",title:"Decision-making in Risk Management",slug:"decision-making-in-risk-management",signatures:"Jan Folkmann Wright",authors:[{id:"254395",title:"Mr.",name:"Jan Folkmann",middleName:null,surname:"Wright",fullName:"Jan Folkmann Wright",slug:"jan-folkmann-wright"}]},{id:"66263",title:"Functional and Technical Methods of Information and Risk Communication",slug:"functional-and-technical-methods-of-information-and-risk-communication",signatures:"Carine J. Yi and Tim Park",authors:[{id:"202156",title:"Dr.",name:"Carine",middleName:"J.",surname:"Yi",fullName:"Carine Yi",slug:"carine-yi"},{id:"285538",title:"Mr.",name:"Tim",middleName:null,surname:"Park",fullName:"Tim Park",slug:"tim-park"}]},{id:"62904",title:"Bank Risk Management: A Regulatory Perspective",slug:"bank-risk-management-a-regulatory-perspective",signatures:"Nguyen Thi Thieu Quang and Christopher Gan",authors:[{id:"256020",title:"Prof.",name:"Christopher",middleName:null,surname:"Gan",fullName:"Christopher Gan",slug:"christopher-gan"},{id:"256021",title:"Ms.",name:"Nguyen Thi Thieu",middleName:null,surname:"Quang",fullName:"Nguyen Thi Thieu Quang",slug:"nguyen-thi-thieu-quang"}]},{id:"63201",title:"Risk Management Practices Adopted by European Financial Firms with a Mediterranean Connection",slug:"risk-management-practices-adopted-by-european-financial-firms-with-a-mediterranean-connection",signatures:"Simon Grima and Frank Bezzina",authors:[{id:"257099",title:"Dr.",name:"Simon",middleName:null,surname:"Grima",fullName:"Simon Grima",slug:"simon-grima"},{id:"257101",title:"Prof.",name:"Frank",middleName:null,surname:"Bezzina",fullName:"Frank Bezzina",slug:"frank-bezzina"}]},{id:"64179",title:"The Internet of Things for Natural Risk Management (Inte.Ri.M.)",slug:"the-internet-of-things-for-natural-risk-management-inte-ri-m-",signatures:"Riccardo Beltramo, Paolo Cantore, Enrica Vesce, Sergio Margarita and\nPaola De Bernardi",authors:[{id:"257332",title:"Prof.",name:"Riccardo",middleName:null,surname:"Beltramo",fullName:"Riccardo Beltramo",slug:"riccardo-beltramo"},{id:"257334",title:"Prof.",name:"Enrica",middleName:null,surname:"Vesce",fullName:"Enrica Vesce",slug:"enrica-vesce"},{id:"257335",title:"Prof.",name:"Paola",middleName:null,surname:"De Bernardi",fullName:"Paola De Bernardi",slug:"paola-de-bernardi"},{id:"257336",title:"Dr.",name:"Paolo",middleName:null,surname:"Cantore",fullName:"Paolo Cantore",slug:"paolo-cantore"},{id:"257337",title:"Prof.",name:"Sergio",middleName:null,surname:"Margarita",fullName:"Sergio Margarita",slug:"sergio-margarita"}]},{id:"64655",title:"Lifecycle Risk Modelling of Complex Projects",slug:"lifecycle-risk-modelling-of-complex-projects",signatures:"Matthew Cook and John P.T. Mo",authors:[{id:"6394",title:"Prof.",name:"John P.T.",middleName:null,surname:"Mo",fullName:"John P.T. Mo",slug:"john-p.t.-mo"},{id:"254858",title:"Ph.D. Student",name:"Matthew",middleName:null,surname:"Cook",fullName:"Matthew Cook",slug:"matthew-cook"}]},{id:"65609",title:"Risk Analysis Related to Cost and Schedule for a Bridge Construction Project",slug:"risk-analysis-related-to-cost-and-schedule-for-a-bridge-construction-project",signatures:"Rafiq M. Choudhry",authors:[{id:"255346",title:"Prof.",name:"Rafiq M.",middleName:null,surname:"Choudhry",fullName:"Rafiq M. Choudhry",slug:"rafiq-m.-choudhry"}]},{id:"64817",title:"Pharmaceutical Projects: Walking along the Risk Management Line",slug:"pharmaceutical-projects-walking-along-the-risk-management-line",signatures:"Jordi Botet",authors:[{id:"143483",title:"Dr.",name:"Jordi",middleName:null,surname:"Botet",fullName:"Jordi Botet",slug:"jordi-botet"}]},{id:"63550",title:"Paradigms of Risk, Hazards and Danger",slug:"paradigms-of-risk-hazards-and-danger",signatures:"Marek Różycki",authors:[{id:"254855",title:"Mr.",name:"Marek",middleName:null,surname:"Rózycki",fullName:"Marek Rózycki",slug:"marek-rozycki"}]},{id:"64630",title:"Process of Risk Management",slug:"process-of-risk-management",signatures:"K. Srinivas",authors:[{id:"255339",title:"Prof.",name:"K.",middleName:null,surname:"Srinivas",fullName:"K. Srinivas",slug:"k.-srinivas"}]}]}],publishedBooks:[{type:"book",id:"7573",title:"Perspectives on Risk, Assessment and Management Paradigms",subtitle:null,isOpenForSubmission:!1,hash:"799ce26efc776b46b7b9f3aedff16edc",slug:"perspectives-on-risk-assessment-and-management-paradigms",bookSignature:"Ali G. Hessami",coverURL:"https://cdn.intechopen.com/books/images_new/7573.jpg",editedByType:"Edited by",editors:[{id:"108303",title:"Prof.",name:"Ali G.",surname:"Hessami",slug:"ali-g.-hessami",fullName:"Ali G. Hessami"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"8834",title:"Managing Wildlife in a Changing World",subtitle:null,isOpenForSubmission:!1,hash:"a27827009edc70af81e12c10aa3e51dd",slug:"managing-wildlife-in-a-changing-world",bookSignature:"Jafari R. Kideghesho",coverURL:"https://cdn.intechopen.com/books/images_new/8834.jpg",editedByType:"Edited by",editors:[{id:"280695",title:"Prof.",name:"Jafari R.",surname:"Kideghesho",slug:"jafari-r.-kideghesho",fullName:"Jafari R. Kideghesho"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10765",title:"Environmental Management",subtitle:"Pollution, Habitat, Ecology, and Sustainability",isOpenForSubmission:!1,hash:"e5ba02fedd7c87f0ab66414f3b07de0c",slug:"environmental-management-pollution-habitat-ecology-and-sustainability",bookSignature:"John P. Tiefenbacher",coverURL:"https://cdn.intechopen.com/books/images_new/10765.jpg",editedByType:"Edited by",editors:[{id:"73876",title:"Dr.",name:"John P.",surname:"Tiefenbacher",slug:"john-p.-tiefenbacher",fullName:"John P. Tiefenbacher"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],publishedBooksByAuthor:[]},onlineFirst:{chapter:{type:"chapter",id:"74141",title:"Italian Crisis Management in 2020",doi:"10.5772/intechopen.94894",slug:"italian-crisis-management-in-2020",body:'
1. Introduction
Dealing with complexity and reducing uncertainty during 2020 crisis is a priority, for Countries, Critical Infrastructures, and companies.
Due to the interdependency of Critical Infrastructures, companies, and the civil society their protection and management represent a significant challenge and, somehow, an opportunity.
The present contribution aims to support the understanding of the tangled pandemic scenario, studying the interdependencies between different sectors and their supply chain, proposing a model addressed to the complexity management for ensure the Business Continuity both of Critical Infrastructure and companies.
The Italian response to the crisis generated by the pandemic was observed, from the study of the impact of the crisis on Critical Infrastructures, to the response strategies, the remediation plans, passing through the reference standards on business continuity and supply chain (in the ISO family of standards).
The imposed lockdown has led to a forced acceleration of digitization, with the challenges and opportunities that could be derived from it.
The crisis management, supported by the experience generated by the avian influenza, together with the support tools provided by the Italian government has proved to be effective and efficient, also relaunching several SMEs through their productive conversion.
The human factor has become evident as the cornerstone of any service, from the provision of essential services falling within the competence of the Critical Infrastructures, which have involved a particular attention to the continuous security and business protocols to be followed, to the most disparate production sectors. It is also necessary to remember how the interconnection between the different sectors and services now characterizes our reality, and therefore how the so call “What-If Analysis” s fundamental in the development of decision support tools for crisis management. In this context is clear that resilience is founded on risk analysis and the drawing of recovery plans, together with measures for an increased control over the value chain.
2. Addressing complexity and impacts of pandemic in critical infrastructure
Dealing with complexity and reducing uncertainty during 2020 crisis is a priority for Countries, Critical Infrastructures, and companies.
Complexity could represent a risk but also an opportunity to create a new competitive advantage.
Society is dependent on composed critical networks, becoming more complex as are strong interdependent both within and between infrastructure systems [1].
Nowadays, complexity and uncertainty assess the search for new and effective management strategies and methods. Embracing unpredictability and planning to adapt is crucial to manage the complexity that cannot be eliminated, although, it can be reduced to manageable levels. Complexity and vulnerability of Critical Infrastructure systems has been explored and assessed [2, 3].
Complexity is related with composite systems and problems that are dynamic, unpredictable, and multi-dimensional. It consists of a collection of interconnected relationships and parts. Unlike traditional “cause and effect” or linear thinking, complexity science is characterized by nonlinearity [4]. Complexity management needs to consider several layouts of complexity, in fact an IC or a company internal value chain is strongly dependent on external complexity.
For each area of complexity regulation, as avoidance and reduction related to causes, transfer, and division, exist several theories, approaches and methods.
Effective complexity management aim to develop an appropriate and effective incident response plan. Finally, complexity must be addressed proactively.
In fact, in such complex scenario, different actors (institutional and non) have responded to the crisis in multiple ways, according to the regulations issued. Moreover, these troubled times show how strategic and essential are some sectors.
In the crisis generated by the pandemic it has been confirmed that the daily life of the citizens depends on the reliability of the Critical Infrastructures (CI) to supply essential services such as energy and water. In recent years, Critical Infrastructure control systems have become more complex, with increasingly interconnected devices; a trend that will probably continue with the Internet of Things.
The need for increased resilience to resist extreme events of both natural and malicious origin has become more acute. With Critical Infrastructure continuously exposed to threats, especially cyber-attacks, there are severe security implications, most notably in the energy sector which is ranked as one of the most affected sectors with the highest incident costs [5]. Any attack of this nature is likely to have knock-on effects on a country’s overall economy and the lives of its citizens.
The pandemic, all in all, has had modest effects on the electrical service. Electricity consumption has been reduced by about 10% on average, but with a very uneven distribution on the Italian territory. Fortunately, the phenomenon has been well controlled and there have been no perceptible effects, but it is easy to imagine the consequences of possible inefficiencies. The effect of the pandemic could be very marked on geopolitical balances, in a context of possible tensions deriving from the rebalancing of the primary energy market and the challenge of the Fourth Industrial Revolution (4IR) [6].
The energy issue brings us back to the more general field of critical infrastructures: electricity and energy system, communication networks, infrastructures for the transport of people and goods (air, sea, rail and road), health system, economic-financial circuits, administrative and state organizations and bodies.
What happened on the Istituto Nazionale della Previdenza Sociale (the Italian Social Security), website is a symptom of a strong criticality in the Country System, where technical shortcomings make the fundamental rights of citizens even more vulnerable, and how IC and companies must equip themselves to manage crisis situations that are not predictable. For this reason there have been several episodes in Italy which have triggered the alarm by the Centro Nazionale Anticrimine Informatico per la Protezione delle Infrastrutture Critiche (CNAIPIC - National Anti-Crime Information Centre for the Protection of Critical Infrastructures).
In terms of crisis management, thanks to the experience of avian influenza (H5N1), which has highlighted how the human factor is the most valuable element for any company and as such must be safeguarded and protected, operators of critical infrastructure have been able to develop a series of effective initiatives, as demonstrated by the fact that no essential service, i.e. the supply of gas, water, electricity, transport, etc. has suffered interruptions or dysfunctions in recent months. And this despite the problems related to difficulties in supply, reduced mobility, the presence of staff in quarantine fiduciary and/or infected and considering the commitment of companies to safeguard the health of their workers.
This achievement is the result of an effort which in recent years has seen a significant change in the role of the security managers, which has shifted to the top management in order to bring strategic choices back to specific task forces capable of having a prompt impact on all levels of the company’s organization, being equipped with the financial and decision-making capacity appropriate to the criticality of the situation [7].
2020 long time crisis and consequent lock down were managed asking to every operators of critical services to maintain business continuity and to guarantee services if critical. This means that not only critical infrastructures at national level, but also critical infrastructures at regional or city or province level had to maintain operation, even having the supply chains partly or completely locked and also even having manpower partly or completely in smart working.
The Office of the Military Advisor of the Presidency of the Council, in consideration of the necessity to guarantee the essential services provided by Critical Infrastructures, has provided the precautionary principles, to which Critical Infrastructure Operators are required to comply in order to contain and contrast the spread of the pandemic, while ensuring the continuity of the supply of essential services, the operability of the facilities and the security of the personnel involved.
These lines suggest, first, a reduction in the number of staff working in situ by reducing activities to those that cannot be postponed for business continuity, and to review the maintenance programs, limiting them to those that cannot be postponed and postponing those that are not indispensable, promoting the adoption of smart working at all levels, necessary for the continuity of the service. The Precautionary Principles highlight the need to provide specific training and tools to operators to prevent and combat the threat of cybersecurity, the importance of which is growing today, to equipping all staff with adequate IT support, including the use of dedicated connections, VPN systems and anything else in order to ensure adequate levels of cybersecurity, including the issue of appropriate rules of conduct by staff working in smart working mode.
Furthermore, is required to prepare all the necessary measures related to sanitization.
The Companies are invited to organize the personnel involved in activities that cannot be postponed at the work sites or field operations in teams composed of the minimum number of people necessary for the safe execution of the various activities. The composition of each team, to increase its resilience, must not, where possible, change over time and specific procedural measures must be taken to avoid, or limit to a minimum, physical interaction between several teams.
With regard to the management of the control and management rooms, given that it is necessary to ensure their functionality in all conditions, it is recommended that all useful measures be taken to contain the pandemic; organizing the staff into several teams and adopting specific and more stringent safeguards for this type of personnel, for example, measures and/or adequately equipping several rooms, possibly in different locations, to allow the alternation of shifts in different rooms and/or sanitized each shift change [8]. Another taken measure was the “voluntary segregation”: the provision of temporary accommodation for groups of people who will operate in the control center for a period of not less than 14 days without physical contact with external personnel. The spaces to which such staff have access will be forbidden to those who do not implement voluntary segregation. To guarantee the continuous rotation of the activities, a second team of staff is set up at the same time, already in isolation at their homes.
Telespazio has set up a three-level system for its Space Center which, before entering the control room, requires a further period of voluntary quarantine within a camp facility located at the Fucino site [9].
The theme of cyber-security is particularly relevant in an increasingly interconnected world where threat vectors multiply and can affect the vulnerabilities of Critical Infrastructures. Moreover, the low level of cybersecurity preparedness of the country system is also reflected in low awareness among citizen-users.
In view of the above, we can say that for the management of emergencies and crises first of all it is necessary to develop a culture of security, supported by the necessary tools and strategies, also considering that we are moving towards the increasing digitalization of any area of the country. In order to do this we can combine the creation of high potential and distributed networks, to avoid in case of stress of infrastructure use, domino effects. It is not possible today to imagine an area of the country that is not covered by essential infrastructures and services that respond to adequate minimum levels of service delivery and security, especially cybersecurity.
It is therefore also essential to start a training process in line with the needs of the world of work and thus adapt to the new professions, together with a plan for the conversion of skills towards new professional qualifications [10].
A fundamental and new aspect of this crisis, which has led to a rethinking of the management of Critical Infrastructures, is that there was a clear “ day before” (in Italy between 10th and 11st March) and a lack of clarity in the “day after”. There is still the sensation of a prolonged crisis and the passage to a remote working that has reduced social relations. This situation has also led to a discontinuity in the visibility that the employer has towards his employees (with respect to how he is and what he feels) that had never been experienced before, while the knowledge of the human model is crucial.
When we make a reading of complexity, we consider a company (or a CI) and analyze it in all that is the flow of its value chain and we retrace all the places and moments of a not physiological complexity.
One type of challenge for Critical Infrastructure Protection is about the dependencies and interdependencies among different Critical Infrastructures [11].
In the context of this extremely long lock-down we had an enormous complexity of relations with suppliers and with those who had to remain in continuity and we would find in the re-opening a strong discontinuity, also in understanding for example the rules with which it was possible to re-open and the responsibilities (in fact, the provision of a suitable team that knows how to interpret the rules is also part of crisis management).
2.1 The Italian production strategy during the 2020 pandemic: statal measures and production conversion
Italian SMEs have worked out an appropriate response strategy to the crisis caused by the 2020 pandemic.
Starting from the importance of the role of each individual entrepreneur, through the constant and daily collection of information on a formal and informal basis, it was possible to identify the strategic levers and focus on new core businesses, based on corporate liquidity, assets and resources.
It emerged that the creation of balanced strategic levers, the make/buy balance, together with the dialog with the stakeholders represented a fundamental element for the conception of a response strategy that represented an example of business resilience.
The crisis has certainly been, and still is, an opportunity to examine which lessons are learning for the future creation of resilience-oriented protocols [12].
There are many Italian companies that have reacted to the crisis by reconverting their production.
Phase two, co-existence with the pandemic, began on 4th May 2020. The Prime Minister’s Decree issued by the Government has made mandatory the use of the mask in closed places accessible to the public, such as public transport and shops. Wearing the mask is mandatory in all situations where “it is not possible to continuously guarantee a safe distance” [13].
Given the emergency and lack of access to this personal protective equipment, more and more companies have chosen to make a concrete contribution and boost their activities after the lockdown by aiming at the reconversion of production chains to manufacture masks. Initiatives that are born to make available the expertise and skills of entire sectors forced by the emergency and the upheaval of daily habits to rebuild their missions and restructure their short, medium- and long-term objectives.
Siare Engineering, an Emilian company specialized in the manufacture of lung ventilators (the unique company in Italy), at the outbreak of the emergency increased its production and changed its export market. In mid-March the company delivered 300 machines to the Civil Protection, originally destined for countries such as South Korea, India, the Philippines and Vietnam, its traditional clients. The company was supported by specialized Army technicians with the aim of producing over 2300 machines, tripling production. Siare Engineering’s efforts were supported by companies such as Ferrari, FCA and Magneti Marelli [14].
Grafica Veneta, a Paduan company active in the printing sector, has reconverted its production to produce 2 million masks. These products, even though they could not be intended for healthcare workers, provided (at a time of dramatic shortage) an initial protection to the population, and were distributed free of charge to the population by the Civil Protection and the Alpini (Italian Army’s mountain infantry).
Mestel Safety, a specialist in snorkeling and diving masks, deposited a patent at the beginning of March to transform this diving equipment into protective masks against contagion [15].
On 23rd March Confindustria Moda launched an adhesion campaign to make masks and PPE, to which 200 companies have immediately joined. A similar initiative was taken by CNA Federmoda. Some of the most important Italian fashion companies responded to the call, such as Armani, Calzedonia, Fendi, Gucci and Valentino.
Prada, on request of the Tuscany Region, has started the production of 80,000 white coats and 110,000 masks [16].
Toscano Alta Sartoria (ex Mabro) has promptly reconfigured its production starting, from March, to produce 3000–4000 masks per day [17].
A choice made also by Valigeria Roncato, a leading company in the sector in the production of luggage made in Italy, which has decided to make a strong contribution to the enduring battle at pandemic by converting its production lines for the production of long-lasting, non-disposable, washable and therefore reusable masks [18]. The core business of the Veneto industry responds to the urgent demand for protective masks that are becoming more and more indispensable.
These solidarity initiatives have been stimulated by the possibility to access incentives to activate the production and supply of medical devices and personal protective equipment (PPE) for the containment and fight against the epidemiological emergency.
And more: to deal with the pandemic, numerous measures have been taken to prevent and contain its expansion and its effects on the economic system. These are emergency measures issued at short distance from each other and linked to each other.
The financial support to SMEs has gone through interventions on the fiscal side, the suspension of the refund of loans, the public guarantee on those granted to companies that have suffered decreases in turnover, a fund for the promotion of Made in Italy, financing.
The objective was to prevent SMEs from shutting down due to lack of liquidity because of the emergency: according to Cerved the system could lose up to 650 billion in revenue between this year and the next.
In this picture, are extremely important the interventions to support the liquidity of the productive network, strongly strengthened by the Legislative Decree n. 23/2020 (so-called Liquidity Decree). This last measure has on one hand modified and on the other hand implemented the extraordinary measures introduced by Decree Law no. 18/2020. This is also thanks to the new regulatory framework for State aid, the EU Commission’s “State Aid Temporary Framework” [19], which has intervened in the meantime. On 14th April 2020, the European Commission authorized the extraordinary support aid schemes provided by Decree Law no. 23/2020. Further interventions to support the liquidity of companies are also contained in Decree-Law No 34 of the 2020.
The economic support measures for businesses adopted with the decrees of March–May 2020 (Decree-Law No 18/2020, Decree-Law No 23/2020 and Decree-Law No 34/2020) are essentially attributable to the following main lines of intervention: liquidity support; export and internationalization support; capitalization support and non-repayable grants; suspension of certain obligations and tax payments, as well as temporary relief on the fixed costs of electricity bills for low-voltage non-domestic users; interventions for companies in crisis, industrial reconversion and development contracts; protection of the national economic and business fabric through changes, some of which are temporary, to the exercise of special powers in sectors of strategic importance (so-called golden power).
Among the measures for companies in crisis, industrial reconversion and development contracts, the following interventions are highly important.
Decree Law No. 18/2020 refinanced the measure of development contracts by €400 million for 2020 (Article 80). The Ministero dello Sviluppo Economico (MISE) Directive of April 15th, 2020 provided for the allocation of resources.
Finally, it should be noted that Law Decree no. 18/2020 authorized the Extraordinary Commissioner for the Epidemiological Emergency to provide funding to companies producing medical devices and personal protective equipment, using INVITALIA as the entity managing the measure. To this end, expenditure of EUR 50 million for 2020 has been authorized (Article 5). The aid scheme was authorized by the EU Commission (on 22nd March 2020). The Ordinance of the Extraordinary Commissioner of 23rd March 2020 (published in the Official Journal on 24 March 2020) implemented the measure.
The resources were assigned to the granting of aid to investment programs aimed at increasing the availability of medical devices and personal protection equipment in the national territory through the expansion of the capacity and/or the reconversion of an existing production unit. The facilities consist of subsidized financing of up to 75% of eligible expenditure. The maximum amount of the facilities that can be granted, in terms of aid (intended as Gross Grant Equivalent), may not exceed 800,000 euros, in accordance with the European Commission Communication of 19th March 2020 - COM (2020) 1863 final - “Temporary Framework for State aid measures to support the economy in the current COVID-19 outbreak”.
Manufacturing masks, gowns, gels and disinfection products, plexiglass spacers, medical devices. These are some of the production reconversions following the pandemic of companies in most of the textile-fashion sector, but also plastics, chemicals, cosmetics, manufacturing, medical, graphics and printing [20].
For some sectors, textiles and chemicals, the new production is opening stable business opportunities in the post 2020 long time crisis, through new channels, which also open opportunities for professional integration.
More than two thirds of companies in the chemical sector, which in the emergency produced alcohol-based disinfectant gels for the hospital sector, are planning to permanently convert, but now intend to extend to direct sales to consumers.
And two thirds of the companies in the plastics sector, which have taken the opportunity to make plexiglass spacers to be installed in the companies, will not stop production. By virtue of a demand that is still expected to be sustained, moreover, more than half of the companies in the textile sector, which are now also aiming to create joint ventures with fashion companies, and almost all the companies in the print sector, which have activated new channels, will maintain active production of masks.
Not all companies, however, are planning to maintain the conversion once the normality is restored, with profound differences between sectors, due to the specificities of the productions.
These are mainly temporary reconversions, on the other hand, for fashion companies that have turned for a few weeks to the production of masks and gowns, as for those in the automotive, cosmetics, medical devices, and manufacturing sectors.
In addition to interventions aimed solely at conversion, the whole world of work has had to face the need to change and adapt to the new situation. Another example of resilience, together with the reconversion of the production of different companies, was the adoption of smart working.
There are data on the transition to remote working collected by Associazione Italiana Esperti Infrastrutture Critiche (AIIC) with the help of other companies. It became clear that before the crisis and therefore until 2019 in companies 71% of employees did not even know what remote working was. During the pandemic 97% of people said they had been working remotely all the time and 43% of people interviewed said they would continue to work remotely.
Regarding the impact on the IT budget: 30% of companies said that investments on the 2020 roadmap projects reset and/or moved to 2021 or suspended.
In contrast, 30% of companies stated that investments will continue without any impact on the 2020 roadmap projects.
Finally, 60% of companies say they still do not know how to proceed with the investments.
The company management, however, has the advantage of being able to provide incentives for sanitization and safety at work: for companies are introduced incentives for sanitization and increased safety at work, through the granting of a tax credit equal to 50% of expenses up to a maximum of 20 thousand euros, and contributions through the establishment of an Inail fund.
The pandemic emergency has not only produced a strong acceleration of digital transformation, smart working and strong demands related to logistics, but also interesting productive reconversions, together with the consciousness of the complex interrelation through different sectors and their supply chain.
For SMEs, the introduction of new products has often meant a real revolution in the business, but able to ensure continuity in production that would otherwise have stopped. Moreover, in case the reconversions are expected to be permanent, are requiring new professional figures to support the activity.
And, most of all, the emergency confirmed the relevance of the human factor.
3. Concrete approaches to critical infrastructure protection
3.1 Supply chain continuity management and lack of manpower during the pandemic
Supply Chain Continuity Management (SCCM) must be considered as a necessary evolution of Business Continuity Management (BCM) models. SCCM is outlined in the ISO 22318 standard which is part of the group of standards for continuity management including ISO 22301, ISO 22313 Security and resilience (ISO 22318), and ISO 28000, which specifies the requirements for a security management system, including those aspects critical to security assurance of the supply chain. SCCM defines continuity in relation to external supplies, third parties or internal entities that play a supplier role in the context of the organization.
The simplified representation of the supply chain therefore provides a composite structure of internal and external suppliers (considering also the flexibility applicable to the relationships between the suppliers) that contribute to the operations of an organization and consequently of its customers.
If the relationship with suppliers is characterized by assets that are mainly intangible and movable and therefore related, for example, to the exchange of information or movable consumer goods, there will be greater control. An example in this sense, during the pandemic emergency management consisted in the possibility of maintaining relationships with suppliers through forms of smart working. This form of collaboration and coordination has been possible mainly between entities operating in sectors consisting of intangible assets such as professional, scientific and technical activities, financial and insurance activities, the activities of extraterritorial organizations, public administration and most professional services and, in general, all sectors that have not been affected by the suspension decrees.
In any case it will be necessary to have a management plan in case of crisis or incidents involving the supply chain.
The adoption of such measures will result in increasing control over the value chain in relation to an organization. In particular, the analysis carried out on the supply chain gives visibility to the mapping of interdependencies between different sectors allowing an analysis that goes beyond the single organization. Network analysis techniques could be combined with criticality and reliability metrics in order to produce composite methods that provide useful information to stakeholders [21].
As for ISO 22301, to plan the SCCM it will be necessary to carry out Impact Analysis activities with the individual suppliers involved, distinguishing critical suppliers from non-critical suppliers. For all relationships with critical suppliers, the guarantee of continuity can be determined by identifying a SCCM strategy to be agreed in transparency with these suppliers. Some strategic approaches may be:
Reducing dependence on a supplier: direct engagement of substitute suppliers for a specific service; increasing on-site stock holding; establishing alternative solutions.
Increasing resilience: loss mitigation; establishing mutual support policies with competitors.
Working with suppliers: creating partnerships with suppliers; setting performance standard; monitoring and dealing with suppliers to increase their resilience; including SCCM requirements in supplier contracts.
The direct effects of the suspension decrees concerned the sectors directly involved and all those sectors that had to sustain the labor shortage caused by the lockdown. While other sectors not directly involved in the suspension decrees, such as financial services or wholesale trade, or sectors more prone to targeted reconversions and the adoption of smart working strategies such as online trade or the fashion sector, were able to stem the direct impact of the emergency or even profit from it.
The Italian National Institute of Statistics in May 2020 has provided a wide range of data and information about the positioning and contribution of the sectors within the Italian production system.
The database is based on the Extended Statistical Register on Economic Performance of Enterprises (Frame-SBS), which contains individual data on all industrial and service enterprises active in the country (about 4.4 million units), supplemented with additional statistical registers that provide detailed information on the characteristics of the employment, as well as import and export enterprises. The data have been further integrated with indicators taken from Italian Accounting.
Considering the enterprises that are part of the universe of reference of the system of Structural Business Statistics (SBS), those that from May 4 are operating in sectors still formally suspended are about 800 thousand (19.1% of the total), with an employment weight of 15.7% on the total of the sectors of industry and market services (excluding the financial sector) [22].
By revising and analyzing the Istat dataset updated in May 2020 [23] with regard to the pandemic, it can be observed in the Figure 1 below that the unavailability of manpower has most directly affected the following sectors in percentage terms:
Other mining and quarrying activities; creative, artistic and entertainment activities; travel agency, tour operator and reservation services and related activities; libraries, archives, museums and other cultural activities; rental and operative leasing activities; real estate activities; activities concerning lotteries, betting, gambling houses; Sports, entertainment and leisure activities; construction of buildings; Mining of metal ores; Manufacture of other transport equipment; Manufacture of leather and related products; Manufacture of motor vehicles, trailers and semi-trailers; Manufacture of furniture; Tobacco industry; Metallurgy; Advertising and market research: 100%
Manufacture of clothing, manufacture of leather and fur articles: 98,48%
Manufacture of fabricated metal products (except machinery and equipment): 93,98%
Manufacture of other non-metallic mineral products: 92,85%
Food service activities: 90,91%
Manufacture of machinery and equipment NCA: 89,48%
Textile industries: 86,77%
Other personal service activities: 83,46%
Wholesale trade (except of motor vehicles and motorcycles): 67,23%
Manufacture of rubber and plastic products: 63,67%.
Figure 1.
Unavailability of manpower.
3.2 Approaches to supply chain what if analysis: dependencies trees
Considering the analyses and remediation plans structured to protect the SCC, it is possible to structure What If models oriented to predict the consequences linked to the lack of a supply.
In relation to the manpower issue, for example, it is possible to structure time-oriented models that consider the negative effects of the manpower.
The Domino Effect methodology applied to manpower aims to study and quantify the consequences of a negative event that causes a lack of personnel and/or supply chain. The model is configured as a visualization of the propagation over time of the negative effects caused by the unavailability of a certain percentage of company personnel.
Such a predictive model can allow the decision maker to simulate different crisis scenarios resulting from the loss of personnel based on the formal organizational structure of the company. In order for the model to be effective, however, it will be essential to feed the model and the collection of information starting from the analysis of the organizational chart and the company function chart.
Information is needed that can be traced back to the following organizational areas:
Administration (ADM)
Actors in charge of Crisis Management (CM)
Functions that have relationships with critical suppliers (SUP)
Business (BSS)
Commercial (COM).
The holistic evolution of this model consists in describing the interdependencies between different sectors starting from the simulation of a disservice concerning a sector. The generic example below can be applied to a single reality in order to understand what long-term effects the lack of manpower, considered as a distinguished sector, could have on the operational continuity of the organization itself (Figure 2).
Figure 2.
Manpower cascading effect on organizational areas.
The severity of the dependency corresponds to the extent to which the Quality of Service (QoS) perceived by the user is deteriorated. Depending on the item, the degradation can be measured by the variation of some specific parameters (coverage, signal reception, delivery time, etc.) with respect to the normal QoS values. In general, the measures that allow to characterize the QoS can be traced back to the general concepts of availability and capacity: the quality with which the service is provided can be described by quantifying the quantity of items provided in comparison to the demand and the time in which the service is actually available. The choice of the temporal moments in which to sample the phenomenon varies according to the item represented.
Metrics commonly agreed to in these cases include: Abandonment Rate; ASA (Average Speed to Answer); TSF (Time Service Factor); FCR (First-Call Resolution); TAT (Turn-Around Time); TRT (total resolution time); MTTR (Mean Time To Recover).
Starting from the elaboration of matrices that consider dependency relations, to represent a domino effect map it is necessary to apply a “filter” based on the degradation level of the service. an item will be considered compromised (and therefore will be represented in the domino effect map) only if the QoS degradation will be higher than a certain threshold, so the service is not considered acceptable (outage).
Various methods are described in the literature to perform this assessment. In general, the most common approaches consist in identifying some indicators that describe the various aspects of the consequences caused by an out of service event.
These indicators can fall into the following categories:
number of people (evaluated in terms of people impacted by the disruption)
economic damage (assessed in terms of the extent of economic losses and/or deterioration of products or services)
effects on public opinion (assessed in terms of impact on public confidence, physical suffering, and disruption of daily life).
Simulation of interdependencies and graph-based model to understand critical infrastructure interdependencies are proposed in literature [24, 25, 26, 27].
The graphical output here proposed (Figure 3) from the described model consists of dependency trees, time-oriented, that describe the collapse of the internal structure of an organization following the manpower “sector” unavailability. This model can be applied to a single organization based on its SC analysis starting considering one or more products and services sectors.
Figure 3.
Manpower dependency tree.
By re-analyzing the ISTAT indices and considering the main sectors activated by the sectors impacted by the manpower shortage, it is possible to identify which related sectors have been most impacted by service interruptions than those listed above.
The sectors impacted indirectly by the shortage of manpower compared with the interruptions of those impacted directly are as follows:
Rental and management of owned or leased properties
Legal and accounting activities
Road freight transport, removal and pipeline transport
Financial service activities (except insurance and pension funding)
Wholesale
Manufacture of fabricated metal products (except machinery and equipment)
As we can see in Figure 4, some sectors such as Financial Services Activities that did not undergo significant effects during the first phase of the lockdown, are subject to an indirect impact due to the activity suspension of their main suppliers.
Figure 4.
Index of indirect impact on SCC for other sectors not highly affected by unavailability of manpower.
3.3 Augustus method and its application by the Italian civil protection
The Augustus method can be considered as another concrete approaches to Critical Infrastructure protection.
The Method is a tool used by the Civil Protection Department of the Italian Republic for emergency planning. The Augustus Method was created in order to equip the Italian Civil Protection Service with a unified strategy for planning the Civil Protection assistance at various levels of competence.
This method is named after the Roman Emperor Augustus (27 B.C. to 14 A.D.), who affirmed that: “The value of planning decreases with the complexity of the state of things.” In detail, Augustus stated that it is impossible to plan a strategy in the smallest detail, because the event when it happens will always present in a different way. The Augustus Method is generated from the need to harmonize the directions of emergency planning.
This approach to the complexity of modern reality was structured and adapted by Elvezio Galanti, who considers the “emergency” (a public situation of particular difficulty and danger) an “organism” with its own life and composed by physiological functions (endocrine system, cardiology, etc.), each one specialized in its own field in which normally carries out its ordinary activity. In the context of civil protection, the “organism” is defined as the territory in which they normally act, and each one because of its specific functions (municipal, regional, health, transport, etc.). In the event of a disaster, these activities must all work together and in synergy.
The Augustus Methodology highlights, therefore, a fundamental aspect of the functioning of the Italian Civil Protection: its systemic nature. A complex apparatus made up of different elements and different organizations, resulting from the functioning of different systems in interaction with each other and with the other organizational systems [28].
In the preventive design phase, the Civil Protection, first of all, must work to collect information (time of occurrence of an event, geological conformation, productive fabric, urban fabric, etc.), then it must proceed with basic examinations (hazard analysis, vulnerability analysis, etc.) and finally a first diagnosis will be made (scenario, i.e. what I expect to happen) and for this reason, facilities will be arranged (monitoring networks, cleaning of riverbeds, seismic adaptation of structures, etc.).
In the absence or in the impossibility of activating these protocols, minimum measures of confrontation will be taken through the constitution of a “resilient cell” to manage the “big 5”, i.e. five macro-areas in which the operational approach is divided into “acute emergency”. These are:
identification of sites per control room;
entry points for expected rescue;
reception areas and first assistance to the population;
identification of proximity sites to coordinate local interventions;
assistance to the population (health and management of any temporary camps for reception and stay).
In the “acute” emergency scenario the Augustus Method becomes a good practice to manage the situation through the identification of 14 basic support functions, or support, that match all the competent and specific institutional figures for each function at territorial level and that contribute to its ordinary and extraordinary functioning. These functions are usually involved during the emergency itself, while in the study phases prior to the emergency, such as forecasting and prevention, they are deactivated and delivered to their specific and ordinary institutional functioning. These functions are: F 1 - Technology and planning; F 2 - Health, social and veterinary assistance; F 3 - Mass-media and information; F 4 - Volunteering; F 5 - Materials and means; F 6 - Transport, traffic and roads; F 7 - Telecommunications; F 8 - Essential services; F 9 - Census of damage to persons and property; F 10 - Operational facilities; F 11 - Local authorities; F 12 - Hazardous materials; F 13 - Assistance to the population; F 14 - Coordination of operational centres.
The design of all coordinated activities and procedures of Civil Protection to respond to any disaster event that is expected in a specific territory is called “Emergency Plan”. The Emergency Plan must be implemented:
Forecasting and Prevention Programs
Information related to:
physical processes causing the risk conditions and their assessments
precursors
events
scenarios
available resources.
Therefore, it is necessary to represent graphically the information necessary for the characterization of possible risk scenarios for the implementation of intervention strategies for the rescue and management of the emergency, rationalizing and targeting the use of men and means.
According to the Method, the following conditions determine the success of a civil protection operation [29]:
unitary direction: the unitary direction of emergency operations is implemented through the coordination of a complex system and not in a sectoral vision of the intervention.
communication: constant exchange of information between the central and peripheral Civil Protection system.
resources: rational and timely use of the resources really available and the availability of the men and means suitable for intervention.
The Emergency Plan structured according to the Augustus Method must be able to answer the following questions:
what calamitous events may reasonably affect the municipality?
which people, facilities and services will be affected or damaged?
what operational organization is necessary to minimize the effects of the event with particular attention to the protection of human life?
to whom are the different responsibilities at the various levels of command and control for emergency management assigned?
To satisfy these needs, it is first of all necessary to define the risk scenarios on the basis of the vulnerability of the portion of the territory concerned (areas, population involved, damaged structures, etc.) in order to have a global and reliable picture of the expected event and therefore to be able to dimension in advance the operational response necessary to overcome the disaster with particular attention to the protection of human life (how many firefighters, how many volunteers, which command and control structures, which roads or escape routes, which shelter structures, health areas, etc.).
The Emergency Plan is therefore a working tool calibrated on a likely situation based on scientific knowledge of the state of risk of the territory, which can be updated and integrated with reference to the list of men and means, but especially when new knowledge is acquired on the conditions of risk involving different assessments of the scenarios, or even when new or additional monitoring and warning systems to the population are available [30].
On the provincial level, the Emergency Plan will identify, at an inter-municipal or provincial scale: on the one side the situations that can configure a more extensive emergency of the single municipality, on the other side the situations, even localized, of greater risk, pointing out, when necessary, the need for an in-depth study of some aspects related to the Municipal scale.
On municipal level, a more detailed level of information is needed to allow the operators of the various components of the Civil Protection to have a reference framework corresponding to the size of the expected event, the population involved, the alternative road system, possible escape routes, waiting areas, shelter, storage areas and so on. Considering that the risk present in a given territory may refer to different types of events (floods, earthquakes, landslides, etc.), the Emergency Plan must provide for one or more “risk scenarios”, which must or may correspond to different types of intervention.
The Italian Civil Protection assumes primary and decisive roles on the institutional scene of civil protection in Italy. This body sums up three fundamental structures at national level:
the Civil Protection Department at the Presidency of the Council of Ministers
the General Directorate of Civil Protection and Firefighting Services at the Ministry of the Interior
the National Seismic Service at the Department of National Technical Services (currently dependent on the Ministry of Public Works).
The Civil Protection plays a key role in the management of national emergencies but not only: the possibility of being activated by the Prefect (Prefetto) for emergencies and in particular cases also for events at local level, makes the Civil Protection an entity that can operate de facto across the board. The Prefect is the cornerstone of the command and coordination structure of the civil protection operational system.
Another key player is represented by the Mayor. He is the determining element in the operational chain of civil protection at municipal level in the assumption of all responsibilities related to civil protection tasks: from the preventive organization of control and monitoring activities to the adoption of emergency measures aimed primarily at safeguarding human life.
It is appropriate, at this point, to make one final consideration: the Emergency Plan is drawn up in any case on the basis of the scientific knowledge possessed at the time of writing, without waiting for studies in progress or future assignments or improvements. An “expeditious” plan, even if imprecise and precautionary, is better than no plan at all. As soon as possible, the Emergency Plan will be reviewed, improved, and completed with more data and more scientific bases.
The key concept of contingency planning is to try to predict all possible variables, however, it is necessary to be aware that it will always be possible, in any emergency, to face something unforeseen.
3.4 The Italian civil protection strategy for the management of the 2020 crisis
The coordination of the members of the National Service of Civil Protection is happening according to the provisions of the Augustus Method thanks to the synchronism of the representatives of each operational function (Health, Volunteering, Telecommunications, etc..) to interact directly with each other.
The intervention model adopted by civil protection for the management of the epidemiological emergency [31] based on the definition of the chain of command and control, the communication flow and the procedures to be activated in relation to the emergency state determined by the spread of the pandemic.
The chain of command and control includes the following levels of coordination:
National level: the Head of the Civil Protection Department ensures the coordination of the necessary interventions, making use of the Department, the components, and operational structures of the National Civil Protection Service, as well as implementing entities. At the Department of Civil Protection is active the Civil Protection Operational Committee, with the task of ensuring the contribution and support of the National Civil Protection System on the basis of the health indications defined by the Ministry of Health, which makes use of the ISS (Istituto Superiore Sanità) and the Scientific Technical Committee specifically established with the OCDPC 630/2020 at the Department.
Regional level: at all Regions must be activated a regional crisis unit, which operates in close connection with the SOR - Regional Operations Room, which must provide for the participation of the Regional Health Contact, which operates in connection with the Health Director of the local health agencies, and in constant contact with a representative of the Chief Prefecture, in order to ensure the connection with the other Prefectures - UTG of the regional territory.
Provincial level: in the provinces in which at least one person is positive for whom the source of transmission is unknown or in any case where there is a case not attributable to a person from an area already affected by the virus, as provided by art. 1, paragraph 1 of Decree-Law no. 6 of 23.02.2020, the Prefect or his delegate provides for the activation of the CCS - Rescue Coordination Centre
Municipal level: in the municipalities or areas in which at least one person is positive for whom the source of transmission is unknown or in any case where there is a case not attributable to a person from an area already affected by the aforementioned virus, as provided by art. 1 paragraph 1 of Decree-Law no. 6 of 23.02.2020, the Mayor or his delegate provides for the activation of the Municipal Operations Centre - COC of the municipality involved and neighboring municipalities in order to implement possible preventive actions.
Therefore, in order to cope with the pandemic and in accordance with the provisions of the Augustus Method, collaborative decision-making processes have been initiated in real time in the operational rooms of the various levels such as:
Centro Coordinamento dei Soccorsi (CCS) - Rescue Coordination Centre
Centro Operativo Comunale (COC) - Municipal Operations Centre
Centro Operativo Misto (COM) - Mixed Operations Centre.
The CCS is the main body at provincial level and is chaired by the Prefect or his delegate. By COC is meant the Municipal Operations Centre, responsible for the activities at municipal-local level, whose maximum point of reference is the Mayor or his delegate (Law 225/1992 - Art. 15). Finally, the COM is the Mixed Operations Centre. They can be more than one and set up ad hoc to be as close as possible to the place of the event.
Originally established as emergency operational centres (i.e. support and operational coordination structures set up and organized exclusively in the full management phase of the emergency following catastrophic events), over time the term has moved to a broader interpretation of the term which also involves structures and organizational divisions of one or more local administrations in the construction of the local civil protection system as well as emergency planning activities to be carried out in ordinary time.
In this emergency caused by the pandemic, a key role is played by the COC, which have been activated in many Italian municipalities [32].
Specifically, the Mayor makes use of the COC to ensure the direction and coordination of rescue and assistance services to the population within his municipal territory in relation to the declaration of the state of emergency issued by the Italian Government. The choice of the location of this Centre must be in earthquake-proof structures, in areas with easy access and not vulnerable to any kind of risk. These facilities must be equipped with a square of enough size to accommodate heavy vehicles and anything else needed in a state of emergency. The COC is responsible for the decision-making levels of the entire municipal structure, summarized in the trade union responsibilities referred to in the previous paragraphs; as a rule, the decision-making level is taken by the Mayor who, through a municipal civil protection system, identifies the actions and strategies necessary to try to keep the infection curve and morbidity index under control. The COC operates in a place of coordination called “operations room” where all the news related to the event converge and where decisions are taken to overcome it. In many municipalities, the COC has been activated by the Mayor as an immediate consequence of the increase in infections within the national territory, and not necessarily in the municipal one, and it will remain operational until the resolution of the pandemic crisis [33].
According to the Civil Protection Operational Measures for the management of the epidemiological emergency [31] actions and operational measures identified for each level of coordination, without prejudice to the provisions issued by the Ministry of Health, are as follows:
information to the population
activation of local volunteering, in connection with the levels of coordination above
organization of actions at the municipal level, in connection with the regional and provincial level, actions to ensure the continuity of essential services, as well as the collection of waste in areas affected, or that may be affected, by urgent measures of containment
organization of actions at the municipal level, in connection with what has been prepared at the regional level, actions aimed at ensuring the continuity of the supply of basic necessities (including fuel supplies) in the areas concerned, or that could be affected by urgent containment measures;
planning, or possible activation, of the actions of assistance to the population of the municipalities concerned, or that could be affected by urgent containment measures
planning and organization of home care services for persons in home quarantine (e.g., basic necessities, medicines, pre-packaged meals…), possibly carried out by personnel of volunteer organizations, appropriately trained.
At this point, it can be stated that the success of a civil protection operation can be achieved if three parameters are satisfied: coordination, communication, and resource management.
4. Conclusion
As with any crisis management strategy, resilience strategies must be planned and prepared during the “peace” period and then implemented, appropriately adapted, during crisis situations. The variable structure, and a proactive response, is what succeeds in giving us a continuity and dealing successfully with the complexity.
Labor shortages directly affected all those sectors that had to close due to the impossibility to convert their business using smart working. Some activities, although part of sectors not directly involved in the lockdown, were indirectly affected by labor shortages caused by the inability of seasonal and commuting staff to move. Finally, the indirect repercussions that have affected those activities that, while remaining operational, have suffered significant economic repercussions due to the interruption of their supply chain caused by the shortage of labor in other sectors.
To be considered in the degree of dependence that an organization might have on its suppliers, beyond its intrinsic resilience, is the degree of flexibility applicable to relations with the various suppliers.
To plan the SCCM it will be necessary to carry out Impact Analysis activities with the individual suppliers involved, distinguishing critical suppliers from non-critical suppliers. For all relationships with critical suppliers continuity can be determined by identifying a SCCM strategy to be agreed transparently with these suppliers. Some strategic approaches may be:
Reducing dependence on a supplier: direct engagement of alternative suppliers for a given service; increasing on-site stock holding; establishing alternative solutions.
Increased resilience: mitigation of losses; identification of a set of alternative suppliers; establishing mutual support policies with competitors.
Working with suppliers: creating partnerships with suppliers; setting performance standards (including through SLAs); monitoring and dealing with suppliers to increase their resilience; including SCCM requirements in supplier contracts.
The adoption of these measures will result in increasing control over the value chain in relation to an organization. In particular, the analysis carried out on the supplier chain gives visibility to the mapping of the interdependencies between the different sectors enabling an analysis that goes beyond the single organization.
Therefore, maximum flexibility and, at the same time, the ability to create the preconditions (e.g. through exercises) is needed to ensure that the best conditions for success are in place in these cases as well.
Moreover, most of all, the 2020 crisis confirmed the relevance of the human factor.
The Italian case is an example of how the set of private initiatives, the support of adequate policies of incentives and support from the State, together with a strong sense of solidarity with the population, can represent a positive reaction to a negative event, and that business strategies oriented towards business continuity are the basis for the development of resilience in the productive sector, and the resilience of the Critical Infrastructures.
\n',keywords:"complex system, emergency management, manpower, cascading effects, resilience",chapterPDFUrl:"https://cdn.intechopen.com/pdfs/74141.pdf",chapterXML:"https://mts.intechopen.com/source/xml/74141.xml",downloadPdfUrl:"/chapter/pdf-download/74141",previewPdfUrl:"/chapter/pdf-preview/74141",totalDownloads:319,totalViews:0,totalCrossrefCites:0,dateSubmitted:"June 29th 2020",dateReviewed:"November 3rd 2020",datePrePublished:"November 21st 2020",datePublished:"July 7th 2021",dateFinished:"November 21st 2020",readingETA:"0",abstract:"Approaches to risk analysis, crisis management and resilience enhancement for Critical Infrastructure (CI) Protection will be considered starting from a case study related to the management of the pandemic in Italy. Business continuity and crisis management models for CI are analyzed aiming to deal with complexity and reduce uncertainty relating pandemic and long-time crisis. Furthermore, is presented a methodology highlighting the functioning of the Italian Civil Protection and its systemic nature: a complex apparatus made up of different elements and organizations, which derives from the functioning of different organizational systems in interaction with each other. As a baseline for the coordination management the Augustus Method is considered for its strategical, tactical and operational aspects. One of the main outputs of the research consists in creating a “what if” forecasting model, configured as a visualization of the propagation of negative effects on the supply chain and manpower over time.",reviewType:"peer-reviewed",bibtexUrl:"/chapter/bibtex/74141",risUrl:"/chapter/ris/74141",signatures:"Luisa Franchina, Alessandro Calabrese, Enrico Scatto and Giulia Inzerilli",book:{id:"10256",type:"book",title:"Issues on Risk Analysis for Critical Infrastructure Protection",subtitle:null,fullTitle:"Issues on Risk Analysis for Critical Infrastructure Protection",slug:"issues-on-risk-analysis-for-critical-infrastructure-protection",publishedDate:"July 7th 2021",bookSignature:"Vittorio Rosato and Antonio Di Pietro",coverURL:"https://cdn.intechopen.com/books/images_new/10256.jpg",licenceType:"CC BY 3.0",editedByType:"Edited by",isbn:"978-1-83962-621-0",printIsbn:"978-1-83962-620-3",pdfIsbn:"978-1-83962-628-9",isAvailableForWebshopOrdering:!0,editors:[{id:"27002",title:"Dr.",name:"Vittorio",middleName:null,surname:"Rosato",slug:"vittorio-rosato",fullName:"Vittorio Rosato"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"}},authors:[{id:"325804",title:"Ph.D.",name:"luisa",middleName:null,surname:"franchina",fullName:"luisa franchina",slug:"luisa-franchina",email:"blustarcacina@gmail.com",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:null},{id:"326318",title:"Dr.",name:"Alessandro",middleName:null,surname:"Calabrese",fullName:"Alessandro Calabrese",slug:"alessandro-calabrese",email:"a.calabrese@hermesbay.com",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:null},{id:"326319",title:"Dr.",name:"Giulia",middleName:null,surname:"Inzerilli",fullName:"Giulia Inzerilli",slug:"giulia-inzerilli",email:"g.inzerilli@hermesbay.com",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:null},{id:"326320",title:"Dr.",name:"Enrico",middleName:null,surname:"Scatto",fullName:"Enrico Scatto",slug:"enrico-scatto",email:"e.scatto@hermesbay.com",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institution:null}],sections:[{id:"sec_1",title:"1. Introduction",level:"1"},{id:"sec_2",title:"2. Addressing complexity and impacts of pandemic in critical infrastructure",level:"1"},{id:"sec_2_2",title:"2.1 The Italian production strategy during the 2020 pandemic: statal measures and production conversion",level:"2"},{id:"sec_4",title:"3. Concrete approaches to critical infrastructure protection",level:"1"},{id:"sec_4_2",title:"3.1 Supply chain continuity management and lack of manpower during the pandemic",level:"2"},{id:"sec_5_2",title:"3.2 Approaches to supply chain what if analysis: dependencies trees",level:"2"},{id:"sec_6_2",title:"3.3 Augustus method and its application by the Italian civil protection",level:"2"},{id:"sec_7_2",title:"3.4 The Italian civil protection strategy for the management of the 2020 crisis",level:"2"},{id:"sec_9",title:"4. Conclusion",level:"1"}],chapterReferences:[{id:"B1",body:'P. Hokstad, I. Utne, I. Vatn; Risk and Interdependencies in Critical Infrastructures: A Guideline for Analysis; Springer; 2012'},{id:"B2",body:'Y. Deng, L. song, Z. Zhou, P. Liu; Complexity and Vulnerability Analysis of Critical Infrastructures: A Methodological Approach; Mathematical Problems in Engineering. 2017'},{id:"B3",body:'M. Tvaronaviciene; Towards internationally tuned approach towards critical infrastructure protection; Journal of Security and Sustainability Issues; 2018'},{id:"B4",body:'Gorzeń-Mitka, M. Okręglicka; Managing Complexity: A Discussion of Current Strategies and Approaches; Procedia Economics and Finance. 27. 438-444; 2015'},{id:"B5",body:'I. Sperstad, G. Kjølle, O. Gjerde; A Comprehensive Framework for Vulnerability Analysis of Extraordinary Events in Power Systems; Reliability Engineering; 2019'},{id:"B6",body:'R. Napoli; Coronavirus e infrastruttura elettrica; AIIC Newsletter no. 06/2020'},{id:"B7",body:'R. Setola; La sicurezza nazionale alla prova della resilienza. L’analisi di Setola; Formiche, 1st April 2020'},{id:"B8",body:'Principi Precauzionali Per Gli Operatori Di Infrastrutture Critiche ai fini della continuità in sicurezza del servizio di interesse pubblico; Ufficio del Consigliere Militare, Segreteria Infrastrutture Critiche; 26th March 2020'},{id:"B9",body:'COVID-19: assicurata la piena funzionalità del Centro di Controllo Galileo al Fucino; Telespazio, 29th April 2020'},{id:"B10",body:'Chiappetta; Italia next ovvero un decalogo per il dopo Coronavirus. Intervento di Chiappetta; Formiche, 5th April 2020'},{id:"B11",body:'E. Luiijf, A. Nieuwenhuijs, M. Klaver, M. Eeten, E. Cruz; Empirical findings on European critical infrastructure dependencies; International Journal of System of Systems Engineering; 2. 3. 10.1504/IJSSE.2010.035378; 2010'},{id:"B12",body:'G. Pisano, R. Sadun, M. Zanini; Lessons from Italy’s Response to Coronavirus; Harvard Business Review; 27th March 2020'},{id:"B13",body:'Decreto Presidente del Consiglio dei Ministri 4th May 2020'},{id:"B14",body:'Emergenza Covid, oltre 3 mila ventilatori polmonari dalla sinergia tra Fca e Siare, la Repubblica; 9th July, 2020'},{id:"B15",body:'È genovese, il brevetto che converte le maschere da sub in protezioni contro la Covid-19; Il Secolo XIX; 24th March, 2020'},{id:"B16",body:'A. Carli; Mascherine e respiratori, ecco le fabbriche che si riconvertono; il Sole 24 Ore, 24th March, 2020'},{id:"B17",body:'P. di Lazzaro; Le mascherine della ex Mabro; Rainews; 17th March 2020'},{id:"B18",body:'A. Nasso; Coronavirus, Roncato ferma produzione valigie: “Facciamo mascherine, nel nostro futuro anche guanti e visiere”; la Repubblica; 28th April, 2020'},{id:"B19",body:'European Commission Press Release; State aid: Commission approves €50 million Italian support scheme for production and supply of medical equipment and masks during Coronavirus outbreak; 22nd March 2020'},{id:"B20",body:'Newsroom; Face masks, sanitiser gel and ventilators – those Italian factories switching their production; Mornong Future; 4th May 2020'},{id:"B21",body:'J. Williams; Critical Flow Centrality Measures on Interdependent Networks with Time-Varying Demands; University of Toronto, Department of Computer Science, Canada; 2019'},{id:"B22",body:'ISTAT; Dataset contributo e posizionamento dei settori produttivi; 12nd May 2020; Available from: https://www.istat.it/it/archivio/239854'},{id:"B23",body:'ISTAT; Nota esplicativa situazione 4 maggio; 11st May 2020; Available from: https://www.istat.it/it/files//2020/04/nota-esplicativa_situazione_04maggio.pdf'},{id:"B24",body:'N. Svendsen, S. Wolthusen; Graph Models of Critical Infrastructure Interdependencies; First International Conference on Autonomous Infrastructure, Management and Security, AIMS 2007'},{id:"B25",body:'S. Dominique, Y. Barbarin, M. Eid; Preparing for the Domino Effect in Crisis Situation D2.1 State of the Art of the R&D Activities in Cascade Effect & Resilience and Global Modelling; Report PREDICT-20151217-D2-1V3; 2018'},{id:"B26",body:'O. Pala, P. Schrum; Simulating Infrastructure Outages: An Open-Source Geospatial Approach; Conference: GeoInformation for Disaster ManagementAt: Istanbul Technical University; 2018'},{id:"B27",body:'A. Rahman, Ḥāfiẓ; Modelling and simulation of interdependencies between the communication and information technology infrastructure and other critical infrastructures; 2009'},{id:"B28",body:'E. Galanti; Il Metodo Augustus; DPC INFORMA “Periodico informativo del Dipartimento della Protezione Civile” (year II; number 4); 1997'},{id:"B29",body:'Presidency of the Council of Ministers, Italian Civil Protection Department; National Risk Assessment; December 2018'},{id:"B30",body:'Provicial Emergency Plan; Metodo Augustus e Funzioni di Supporto; Assessorato alla Protezione Civile; 2008'},{id:"B31",body:'Dipartimento di Protezione Civile; Misure operative di protezione civile per la gestione dell’emergenza epidemiologica da Covid-19; 4th May 2020'},{id:"B32",body:'Comune di Olevano sul Tusciano; Istituzione del “Centro Operativo Comunale (COC)” per l’emergenza di protezione civile COVID-19, 23rd March 2020; https://www.comune.bergamo.it/node/188215'},{id:"B33",body:'Emergenza Coronavirus Covid-19 Sul Territorio Nazionale – Attivazione C.O.C. 8th March 2020, https://www.olevanosultusciano.gov.it/avvisi/emergenza-coronavirus-covid-19-sul-territorio-nazionale-attivazione-c-o-c-centro-operativo-comunale/'}],footnotes:[],contributors:[{corresp:null,contributorFullName:"Luisa Franchina",address:null,affiliation:'
'}],corrections:null},book:{id:"10256",type:"book",title:"Issues on Risk Analysis for Critical Infrastructure Protection",subtitle:null,fullTitle:"Issues on Risk Analysis for Critical Infrastructure Protection",slug:"issues-on-risk-analysis-for-critical-infrastructure-protection",publishedDate:"July 7th 2021",bookSignature:"Vittorio Rosato and Antonio Di Pietro",coverURL:"https://cdn.intechopen.com/books/images_new/10256.jpg",licenceType:"CC BY 3.0",editedByType:"Edited by",isbn:"978-1-83962-621-0",printIsbn:"978-1-83962-620-3",pdfIsbn:"978-1-83962-628-9",isAvailableForWebshopOrdering:!0,editors:[{id:"27002",title:"Dr.",name:"Vittorio",middleName:null,surname:"Rosato",slug:"vittorio-rosato",fullName:"Vittorio Rosato"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"}}},profile:{item:{id:"58672",title:"Mr.",name:"Vinit",middleName:null,surname:"Kumar",email:"vinit@nccs.res.in",fullName:"Vinit Kumar",slug:"vinit-kumar",position:null,biography:null,institutionString:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",totalCites:0,totalChapterViews:"0",outsideEditionCount:0,totalAuthoredChapters:"1",totalEditedBooks:"0",personalWebsiteURL:null,twitterURL:null,linkedinURL:null,institution:null},booksEdited:[],chaptersAuthored:[{id:"23265",title:"Therapeutic Targeting of Osteopontin in Breast Cancer Cells",slug:"therapeutic-targeting-of-osteopontin-in-breast-cancer-cells",abstract:null,signatures:"Gopal C. Kundu, Supriya Saraswati, Megha Sanyal, Anuradha Bulbule, Anuja Ramdasi, Dhiraj Kumar, Reeti Behera, Mansoor Ahmed, Goutam Chakraborty, Vinit Kumar, Shalini Jain, Gowrishankar S. and Pompom Ghosh",authors:[{id:"41811",title:"Dr.",name:"Gopal",surname:"Kundu",fullName:"Gopal Kundu",slug:"gopal-kundu",email:"gopalkundu@hotmail.com"},{id:"58670",title:"Ms.",name:"Reeti",surname:"Behera",fullName:"Reeti Behera",slug:"reeti-behera",email:"reeti@nccs.res.in"},{id:"58671",title:"Dr.",name:"Mansoor",surname:"Ahmed",fullName:"Mansoor Ahmed",slug:"mansoor-ahmed",email:"mansoor@nccs.res.in"},{id:"58672",title:"Mr.",name:"Vinit",surname:"Kumar",fullName:"Vinit Kumar",slug:"vinit-kumar",email:"vinit@nccs.res.in"}],book:{id:"1277",title:"Breast Cancer",slug:"breast-cancer-current-and-alternative-therapeutic-modalities",productType:{id:"1",title:"Edited Volume"}}}],collaborators:[{id:"38420",title:"Dr.",name:"Rita",surname:"Nahta",slug:"rita-nahta",fullName:"Rita Nahta",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Emory University",institutionURL:null,country:{name:"United States of America"}}},{id:"41811",title:"Dr.",name:"Gopal",surname:"Kundu",slug:"gopal-kundu",fullName:"Gopal Kundu",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"42351",title:"Prof.",name:"Kathrin",surname:"Kirsch",slug:"kathrin-kirsch",fullName:"Kathrin Kirsch",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Boston University School of Medicine",institutionURL:null,country:{name:"United States of America"}}},{id:"44920",title:"Prof.",name:"Peter",surname:"Fedorocko",slug:"peter-fedorocko",fullName:"Peter Fedorocko",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"56184",title:"Dr.",name:"Peter",surname:"Ferenc",slug:"peter-ferenc",fullName:"Peter Ferenc",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"56186",title:"Dr.",name:"Ján",surname:"Kovaľ",slug:"jan-koval",fullName:"Ján Kovaľ",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"58670",title:"Ms.",name:"Reeti",surname:"Behera",slug:"reeti-behera",fullName:"Reeti Behera",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"58671",title:"Dr.",name:"Mansoor",surname:"Ahmed",slug:"mansoor-ahmed",fullName:"Mansoor Ahmed",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"60654",title:"Dr",name:"Joerg",surname:"Kumbrink",slug:"joerg-kumbrink",fullName:"Joerg Kumbrink",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"62241",title:"Ms.",name:"Sylvia",surname:"Shabaya",slug:"sylvia-shabaya",fullName:"Sylvia Shabaya",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Emory University",institutionURL:null,country:{name:"United States of America"}}}]},generic:{page:{slug:"WIS-cost",title:"What Does It Cost?",intro:"
Open Access publishing helps remove barriers and allows everyone to access valuable information, but article and book processing charges also exclude talented authors and editors who can’t afford to pay. The goal of our Women in Science program is to charge zero APCs, so none of our authors or editors have to pay for publication.
",metaTitle:"What Does It Cost?",metaDescription:"Open Access publishing helps remove barriers and allows everyone to access valuable information, but article and book processing charges also exclude talented authors and editors who can’t afford to pay. The goal of our Women in Science program is to charge zero APCs, so none of our authors or editors have to pay for publication.",metaKeywords:null,canonicalURL:null,contentRaw:'[{"type":"htmlEditorComponent","content":"
We are currently in the process of collecting sponsorship. If you have any ideas or would like to help sponsor this ambitious program, we’d love to hear from you. Contact us at info@intechopen.com.
\\n\\n
All of our IntechOpen sponsors are in good company! The research in past IntechOpen books and chapters have been funded by:
\\n\\n
\\n\\t
European Commission
\\n\\t
Bill and Melinda Gates Foundation
\\n\\t
Wellcome Trust
\\n\\t
National Institute of Health (NIH)
\\n\\t
National Science Foundation (NSF)
\\n\\t
National Institute of Standards and Technology (NIST)
We are currently in the process of collecting sponsorship. If you have any ideas or would like to help sponsor this ambitious program, we’d love to hear from you. Contact us at info@intechopen.com.
\n\n
All of our IntechOpen sponsors are in good company! The research in past IntechOpen books and chapters have been funded by:
\n\n
\n\t
European Commission
\n\t
Bill and Melinda Gates Foundation
\n\t
Wellcome Trust
\n\t
National Institute of Health (NIH)
\n\t
National Science Foundation (NSF)
\n\t
National Institute of Standards and Technology (NIST)
\n\t
Research Councils United Kingdom (RCUK)
\n\t
Foundation for Science and Technology (FCT)
\n\t
Chinese Academy of Sciences
\n\t
Natural Science Foundation of China (NSFC)
\n\t
German Research Foundation (DFG)
\n\t
Max Planck Institute
\n\t
Austrian Science Fund (FWF)
\n\t
Australian Research Council (ARC)
\n
\n'}]},successStories:{items:[]},authorsAndEditors:{filterParams:{sort:"featured,name"},profiles:[],filtersByRegion:[],offset:0,limit:12,total:null},chapterEmbeded:{data:{}},editorApplication:{success:null,errors:{}},ofsBooks:{filterParams:{hasNoEditors:"1",sort:"dateEndThirdStepPublish",src:"EDCMP",topicId:"10"},books:[{type:"book",id:"11834",title:"Steppe Geography",subtitle:null,isOpenForSubmission:!0,hash:"363517fa6f079daf94c51ea1b91fed2a",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/11834.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11836",title:"Estuary Research",subtitle:null,isOpenForSubmission:!0,hash:"ef822fc9eee5600aeb7e45492e04a6e7",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/11836.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11837",title:"The Mediterranean",subtitle:null,isOpenForSubmission:!0,hash:"bbb25987a982d61da4f47fb13614ba3c",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/11837.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11846",title:"Seabed",subtitle:null,isOpenForSubmission:!0,hash:"1b1698a2d8d36b5ec3571c20486eb2c9",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/11846.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"12002",title:"Oceanography",subtitle:null,isOpenForSubmission:!0,hash:"b48da2053b7a270a24db1eeaea08f16b",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/12002.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"12003",title:"Rural Areas",subtitle:null,isOpenForSubmission:!0,hash:"5d6bf787bf04690d8773b4d47bc54353",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/12003.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"12004",title:"Tropical Forests",subtitle:null,isOpenForSubmission:!0,hash:"1478a073e834c74e589098e43f49d1d8",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/12004.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"12008",title:"Soil Erosion",subtitle:null,isOpenForSubmission:!0,hash:"1eaa50d78d66b865dad58f70ea80a0cb",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/12008.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"12010",title:"New Findings on Black Holes",subtitle:null,isOpenForSubmission:!0,hash:"5e31be1486a9d2981dcadb9451f33793",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/12010.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11999",title:"Earthquakes - New Insights",subtitle:null,isOpenForSubmission:!0,hash:"911a25fd67eda2c5dd5dc068885ab6c1",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/11999.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"12000",title:"Natural Hazards",subtitle:null,isOpenForSubmission:!0,hash:"d9fad96ccf42b288f2134775f6a8a1be",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/12000.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"12001",title:"Polar Climate",subtitle:null,isOpenForSubmission:!0,hash:"b226f7ff46cf93d4dc25aa49b23cc118",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/12001.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],filtersByTopic:[{group:"topic",caption:"Agricultural and Biological Sciences",value:5,count:39},{group:"topic",caption:"Biochemistry, Genetics and Molecular Biology",value:6,count:11},{group:"topic",caption:"Business, Management and Economics",value:7,count:7},{group:"topic",caption:"Chemistry",value:8,count:17},{group:"topic",caption:"Computer and Information Science",value:9,count:16},{group:"topic",caption:"Earth and Planetary Sciences",value:10,count:15},{group:"topic",caption:"Engineering",value:11,count:32},{group:"topic",caption:"Environmental Sciences",value:12,count:7},{group:"topic",caption:"Immunology and Microbiology",value:13,count:11},{group:"topic",caption:"Materials Science",value:14,count:11},{group:"topic",caption:"Mathematics",value:15,count:6},{group:"topic",caption:"Medicine",value:16,count:100},{group:"topic",caption:"Nanotechnology and Nanomaterials",value:17,count:2},{group:"topic",caption:"Neuroscience",value:18,count:7},{group:"topic",caption:"Pharmacology, Toxicology and Pharmaceutical Science",value:19,count:11},{group:"topic",caption:"Physics",value:20,count:2},{group:"topic",caption:"Psychology",value:21,count:7},{group:"topic",caption:"Robotics",value:22,count:2},{group:"topic",caption:"Social Sciences",value:23,count:32},{group:"topic",caption:"Technology",value:24,count:1}],offset:12,limit:12,total:15},popularBooks:{featuredBooks:[{type:"book",id:"9974",title:"E-Learning and Digital Education in the Twenty-First Century",subtitle:null,isOpenForSubmission:!1,hash:"88b58d66e975df20425fc1dfd22d53aa",slug:"e-learning-and-digital-education-in-the-twenty-first-century",bookSignature:"M. Mahruf C. Shohel",coverURL:"https://cdn.intechopen.com/books/images_new/9974.jpg",editors:[{id:"94099",title:"Dr.",name:"M. Mahruf C.",middleName:null,surname:"Shohel",slug:"m.-mahruf-c.-shohel",fullName:"M. Mahruf C. Shohel"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11001",title:"Density Functional Theory",subtitle:"Recent Advances, New Perspectives and Applications",isOpenForSubmission:!1,hash:"82d53383af78ab41eb982086c02fb2bb",slug:"density-functional-theory-recent-advances-new-perspectives-and-applications",bookSignature:"Daniel Glossman-Mitnik",coverURL:"https://cdn.intechopen.com/books/images_new/11001.jpg",editors:[{id:"198499",title:"Dr.",name:"Daniel",middleName:null,surname:"Glossman-Mitnik",slug:"daniel-glossman-mitnik",fullName:"Daniel Glossman-Mitnik"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10356",title:"Natural Medicinal Plants",subtitle:null,isOpenForSubmission:!1,hash:"943e56ccaaf19ff696d25aa638ae37d6",slug:"natural-medicinal-plants",bookSignature:"Hany A. El-Shemy",coverURL:"https://cdn.intechopen.com/books/images_new/10356.jpg",editors:[{id:"54719",title:"Prof.",name:"Hany",middleName:null,surname:"El-Shemy",slug:"hany-el-shemy",fullName:"Hany El-Shemy"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11752",title:"Natural Drugs from Plants",subtitle:null,isOpenForSubmission:!1,hash:"a0a83c0822608ef7592bf16a5ed0ada4",slug:"natural-drugs-from-plants",bookSignature:"Hany A. El-Shemy",coverURL:"https://cdn.intechopen.com/books/images_new/11752.jpg",editors:[{id:"54719",title:"Prof.",name:"Hany",middleName:null,surname:"El-Shemy",slug:"hany-el-shemy",fullName:"Hany El-Shemy"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10251",title:"Plankton Communities",subtitle:null,isOpenForSubmission:!1,hash:"e11e441ca2d2d5f631b1b4704505cfb6",slug:"plankton-communities",bookSignature:"Leonel Pereira and Ana Marta Gonçalves",coverURL:"https://cdn.intechopen.com/books/images_new/10251.jpg",editors:[{id:"279788",title:"Dr.",name:"Leonel",middleName:null,surname:"Pereira",slug:"leonel-pereira",fullName:"Leonel Pereira"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10830",title:"Animal Feed Science and Nutrition",subtitle:"Production, Health and Environment",isOpenForSubmission:!1,hash:"79944fc8fbbaa329aed6fde388154832",slug:"animal-feed-science-and-nutrition-production-health-and-environment",bookSignature:"Amlan Kumar Patra",coverURL:"https://cdn.intechopen.com/books/images_new/10830.jpg",editors:[{id:"310962",title:"Dr.",name:"Amlan",middleName:"Kumar",surname:"Patra",slug:"amlan-patra",fullName:"Amlan Patra"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10584",title:"Engineered Wood Products for Construction",subtitle:null,isOpenForSubmission:!1,hash:"421757c56a3735986055250821275a51",slug:"engineered-wood-products-for-construction",bookSignature:"Meng Gong",coverURL:"https://cdn.intechopen.com/books/images_new/10584.jpg",editors:[{id:"274242",title:"Dr.",name:"Meng",middleName:null,surname:"Gong",slug:"meng-gong",fullName:"Meng Gong"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9670",title:"Current Trends in Wheat Research",subtitle:null,isOpenForSubmission:!1,hash:"89d795987f1747a76eee532700d2093d",slug:"current-trends-in-wheat-research",bookSignature:"Mahmood-ur-Rahman Ansari",coverURL:"https://cdn.intechopen.com/books/images_new/9670.jpg",editors:[{id:"185476",title:"Dr.",name:"Mahmood-ur-Rahman",middleName:null,surname:"Ansari",slug:"mahmood-ur-rahman-ansari",fullName:"Mahmood-ur-Rahman Ansari"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9032",title:"Corporate Social Responsibility",subtitle:null,isOpenForSubmission:!1,hash:"f609bf3251d7cc7bae0099a4374adfc3",slug:"corporate-social-responsibility",bookSignature:"Beatrice Orlando",coverURL:"https://cdn.intechopen.com/books/images_new/9032.jpg",editors:[{id:"232969",title:"Prof.",name:"Beatrice",middleName:null,surname:"Orlando",slug:"beatrice-orlando",fullName:"Beatrice Orlando"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10681",title:"Biodegradation Technology of Organic and Inorganic Pollutants",subtitle:null,isOpenForSubmission:!1,hash:"9a6e10e02788092872fd249436898e97",slug:"biodegradation-technology-of-organic-and-inorganic-pollutants",bookSignature:"Kassio Ferreira Mendes, Rodrigo Nogueira de Sousa and Kamila Cabral Mielke",coverURL:"https://cdn.intechopen.com/books/images_new/10681.jpg",editors:[{id:"197720",title:"Ph.D.",name:"Kassio",middleName:null,surname:"Ferreira Mendes",slug:"kassio-ferreira-mendes",fullName:"Kassio Ferreira Mendes"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9808",title:"Contemporary Topics in Patient Safety",subtitle:"Volume 1",isOpenForSubmission:!1,hash:"fb6371607c2c6c02c6a2af8892765aba",slug:"contemporary-topics-in-patient-safety-volume-1",bookSignature:"Stanislaw P. Stawicki and Michael S. Firstenberg",coverURL:"https://cdn.intechopen.com/books/images_new/9808.jpg",editors:[{id:"181694",title:"Dr.",name:"Stanislaw P.",middleName:null,surname:"Stawicki",slug:"stanislaw-p.-stawicki",fullName:"Stanislaw P. Stawicki"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9544",title:"Global Trade in the Emerging Business Environment",subtitle:null,isOpenForSubmission:!1,hash:"fb8cb09b9599246add78d508a98273d5",slug:"global-trade-in-the-emerging-business-environment",bookSignature:"Muhammad Mohiuddin, Jingbin Wang , Md. Samim Al Azad and Selim Ahmed",coverURL:"https://cdn.intechopen.com/books/images_new/9544.jpg",editors:[{id:"418514",title:"Dr.",name:"Muhammad",middleName:null,surname:"Mohiuddin",slug:"muhammad-mohiuddin",fullName:"Muhammad Mohiuddin"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}}],offset:12,limit:12,total:4380},hotBookTopics:{hotBooks:[],offset:0,limit:12,total:null},publish:{},publishingProposal:{success:null,errors:{}},books:{featuredBooks:[{type:"book",id:"9974",title:"E-Learning and Digital Education in the Twenty-First Century",subtitle:null,isOpenForSubmission:!1,hash:"88b58d66e975df20425fc1dfd22d53aa",slug:"e-learning-and-digital-education-in-the-twenty-first-century",bookSignature:"M. Mahruf C. Shohel",coverURL:"https://cdn.intechopen.com/books/images_new/9974.jpg",publishedDate:"May 18th 2022",numberOfDownloads:3385,editors:[{id:"94099",title:"Dr.",name:"M. Mahruf C.",middleName:null,surname:"Shohel",slug:"m.-mahruf-c.-shohel",fullName:"M. Mahruf C. Shohel"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11001",title:"Density Functional Theory",subtitle:"Recent Advances, New Perspectives and Applications",isOpenForSubmission:!1,hash:"82d53383af78ab41eb982086c02fb2bb",slug:"density-functional-theory-recent-advances-new-perspectives-and-applications",bookSignature:"Daniel Glossman-Mitnik",coverURL:"https://cdn.intechopen.com/books/images_new/11001.jpg",publishedDate:"May 18th 2022",numberOfDownloads:1875,editors:[{id:"198499",title:"Dr.",name:"Daniel",middleName:null,surname:"Glossman-Mitnik",slug:"daniel-glossman-mitnik",fullName:"Daniel Glossman-Mitnik"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10356",title:"Natural Medicinal Plants",subtitle:null,isOpenForSubmission:!1,hash:"943e56ccaaf19ff696d25aa638ae37d6",slug:"natural-medicinal-plants",bookSignature:"Hany A. El-Shemy",coverURL:"https://cdn.intechopen.com/books/images_new/10356.jpg",publishedDate:"May 11th 2022",numberOfDownloads:3842,editors:[{id:"54719",title:"Prof.",name:"Hany",middleName:null,surname:"El-Shemy",slug:"hany-el-shemy",fullName:"Hany El-Shemy"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"11752",title:"Natural Drugs from Plants",subtitle:null,isOpenForSubmission:!1,hash:"a0a83c0822608ef7592bf16a5ed0ada4",slug:"natural-drugs-from-plants",bookSignature:"Hany A. El-Shemy",coverURL:"https://cdn.intechopen.com/books/images_new/11752.jpg",publishedDate:"May 11th 2022",numberOfDownloads:3008,editors:[{id:"54719",title:"Prof.",name:"Hany",middleName:null,surname:"El-Shemy",slug:"hany-el-shemy",fullName:"Hany El-Shemy"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10251",title:"Plankton Communities",subtitle:null,isOpenForSubmission:!1,hash:"e11e441ca2d2d5f631b1b4704505cfb6",slug:"plankton-communities",bookSignature:"Leonel Pereira and Ana Marta Gonçalves",coverURL:"https://cdn.intechopen.com/books/images_new/10251.jpg",publishedDate:"May 18th 2022",numberOfDownloads:1109,editors:[{id:"279788",title:"Dr.",name:"Leonel",middleName:null,surname:"Pereira",slug:"leonel-pereira",fullName:"Leonel Pereira"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10830",title:"Animal Feed Science and Nutrition",subtitle:"Production, Health and Environment",isOpenForSubmission:!1,hash:"79944fc8fbbaa329aed6fde388154832",slug:"animal-feed-science-and-nutrition-production-health-and-environment",bookSignature:"Amlan Kumar Patra",coverURL:"https://cdn.intechopen.com/books/images_new/10830.jpg",publishedDate:"May 18th 2022",numberOfDownloads:1010,editors:[{id:"310962",title:"Dr.",name:"Amlan",middleName:"Kumar",surname:"Patra",slug:"amlan-patra",fullName:"Amlan Patra"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10584",title:"Engineered Wood Products for Construction",subtitle:null,isOpenForSubmission:!1,hash:"421757c56a3735986055250821275a51",slug:"engineered-wood-products-for-construction",bookSignature:"Meng Gong",coverURL:"https://cdn.intechopen.com/books/images_new/10584.jpg",publishedDate:"April 28th 2022",numberOfDownloads:3918,editors:[{id:"274242",title:"Dr.",name:"Meng",middleName:null,surname:"Gong",slug:"meng-gong",fullName:"Meng Gong"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9670",title:"Current Trends in Wheat Research",subtitle:null,isOpenForSubmission:!1,hash:"89d795987f1747a76eee532700d2093d",slug:"current-trends-in-wheat-research",bookSignature:"Mahmood-ur-Rahman Ansari",coverURL:"https://cdn.intechopen.com/books/images_new/9670.jpg",publishedDate:"May 11th 2022",numberOfDownloads:1654,editors:[{id:"185476",title:"Dr.",name:"Mahmood-ur-Rahman",middleName:null,surname:"Ansari",slug:"mahmood-ur-rahman-ansari",fullName:"Mahmood-ur-Rahman Ansari"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9032",title:"Corporate Social Responsibility",subtitle:null,isOpenForSubmission:!1,hash:"f609bf3251d7cc7bae0099a4374adfc3",slug:"corporate-social-responsibility",bookSignature:"Beatrice Orlando",coverURL:"https://cdn.intechopen.com/books/images_new/9032.jpg",publishedDate:"March 16th 2022",numberOfDownloads:7686,editors:[{id:"232969",title:"Prof.",name:"Beatrice",middleName:null,surname:"Orlando",slug:"beatrice-orlando",fullName:"Beatrice Orlando"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10681",title:"Biodegradation Technology of Organic and Inorganic Pollutants",subtitle:null,isOpenForSubmission:!1,hash:"9a6e10e02788092872fd249436898e97",slug:"biodegradation-technology-of-organic-and-inorganic-pollutants",bookSignature:"Kassio Ferreira Mendes, Rodrigo Nogueira de Sousa and Kamila Cabral Mielke",coverURL:"https://cdn.intechopen.com/books/images_new/10681.jpg",publishedDate:"April 20th 2022",numberOfDownloads:3444,editors:[{id:"197720",title:"Ph.D.",name:"Kassio",middleName:null,surname:"Ferreira Mendes",slug:"kassio-ferreira-mendes",fullName:"Kassio Ferreira Mendes"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}}],latestBooks:[{type:"book",id:"10251",title:"Plankton Communities",subtitle:null,isOpenForSubmission:!1,hash:"e11e441ca2d2d5f631b1b4704505cfb6",slug:"plankton-communities",bookSignature:"Leonel Pereira and Ana Marta Gonçalves",coverURL:"https://cdn.intechopen.com/books/images_new/10251.jpg",editedByType:"Edited by",publishedDate:"May 18th 2022",editors:[{id:"279788",title:"Dr.",name:"Leonel",middleName:null,surname:"Pereira",slug:"leonel-pereira",fullName:"Leonel Pereira"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10830",title:"Animal Feed Science and Nutrition",subtitle:"Production, Health and Environment",isOpenForSubmission:!1,hash:"79944fc8fbbaa329aed6fde388154832",slug:"animal-feed-science-and-nutrition-production-health-and-environment",bookSignature:"Amlan Kumar Patra",coverURL:"https://cdn.intechopen.com/books/images_new/10830.jpg",editedByType:"Edited by",publishedDate:"May 18th 2022",editors:[{id:"310962",title:"Dr.",name:"Amlan",middleName:"Kumar",surname:"Patra",slug:"amlan-patra",fullName:"Amlan Patra"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10853",title:"Recent Advances in Polynomials",subtitle:null,isOpenForSubmission:!1,hash:"9e8671bae09ccaa8b8e276c639a737fc",slug:"recent-advances-in-polynomials",bookSignature:"Kamal Shah",coverURL:"https://cdn.intechopen.com/books/images_new/10853.jpg",editedByType:"Edited by",publishedDate:"May 18th 2022",editors:[{id:"231748",title:"Dr.",name:"Kamal",middleName:null,surname:"Shah",slug:"kamal-shah",fullName:"Kamal Shah"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10871",title:"Computed-Tomography (CT) Scan",subtitle:null,isOpenForSubmission:!1,hash:"966d8cf74fa27eea1b9cbc9a6ee94993",slug:"computed-tomography-ct-scan",bookSignature:"Reda R. Gharieb",coverURL:"https://cdn.intechopen.com/books/images_new/10871.jpg",editedByType:"Edited by",publishedDate:"May 18th 2022",editors:[{id:"225387",title:"Prof.",name:"Reda R.",middleName:"R.",surname:"Gharieb",slug:"reda-r.-gharieb",fullName:"Reda R. Gharieb"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10903",title:"Genetically Modified Plants and Beyond",subtitle:null,isOpenForSubmission:!1,hash:"4d7ed4faab99c92cd4d676dc86501df9",slug:"genetically-modified-plants-and-beyond",bookSignature:"Idah Sithole Niang",coverURL:"https://cdn.intechopen.com/books/images_new/10903.jpg",editedByType:"Edited by",publishedDate:"May 18th 2022",editors:[{id:"90172",title:"Prof.",name:"Idah",middleName:null,surname:"Sithole-Niang",slug:"idah-sithole-niang",fullName:"Idah Sithole-Niang"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10904",title:"Fusarium",subtitle:"An Overview of the Genus",isOpenForSubmission:!1,hash:"49d9063e43f94bd1517d65fbc58b93c3",slug:"fusarium-an-overview-of-the-genus",bookSignature:"Seyed Mahyar Mirmajlessi",coverURL:"https://cdn.intechopen.com/books/images_new/10904.jpg",editedByType:"Edited by",publishedDate:"May 18th 2022",editors:[{id:"100573",title:"Dr.",name:"Seyed Mahyar",middleName:null,surname:"Mirmajlessi",slug:"seyed-mahyar-mirmajlessi",fullName:"Seyed Mahyar Mirmajlessi"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10654",title:"Brain-Computer Interface",subtitle:null,isOpenForSubmission:!1,hash:"a5308884068cc53ed31c6baba756857f",slug:"brain-computer-interface",bookSignature:"Vahid Asadpour",coverURL:"https://cdn.intechopen.com/books/images_new/10654.jpg",editedByType:"Edited by",publishedDate:"May 18th 2022",editors:[{id:"165328",title:"Dr.",name:"Vahid",middleName:null,surname:"Asadpour",slug:"vahid-asadpour",fullName:"Vahid Asadpour"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10676",title:"Recent Applications in Graph Theory",subtitle:null,isOpenForSubmission:!1,hash:"900c60742d224080732bd16bd25ccba8",slug:"recent-applications-in-graph-theory",bookSignature:"Harun Pirim",coverURL:"https://cdn.intechopen.com/books/images_new/10676.jpg",editedByType:"Edited by",publishedDate:"May 18th 2022",editors:[{id:"146092",title:"Dr.",name:"Harun",middleName:null,surname:"Pirim",slug:"harun-pirim",fullName:"Harun Pirim"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11196",title:"New Updates in E-Learning",subtitle:null,isOpenForSubmission:!1,hash:"6afaadf68e2a0a4b370ac5ceb5ca89c6",slug:"new-updates-in-e-learning",bookSignature:"Eduard Babulak",coverURL:"https://cdn.intechopen.com/books/images_new/11196.jpg",editedByType:"Edited by",publishedDate:"May 18th 2022",editors:[{id:"10086",title:"Prof.",name:"Eduard",middleName:null,surname:"Babulak",slug:"eduard-babulak",fullName:"Eduard Babulak"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9974",title:"E-Learning and Digital Education in the Twenty-First Century",subtitle:null,isOpenForSubmission:!1,hash:"88b58d66e975df20425fc1dfd22d53aa",slug:"e-learning-and-digital-education-in-the-twenty-first-century",bookSignature:"M. Mahruf C. Shohel",coverURL:"https://cdn.intechopen.com/books/images_new/9974.jpg",editedByType:"Edited by",publishedDate:"May 18th 2022",editors:[{id:"94099",title:"Dr.",name:"M. Mahruf C.",middleName:null,surname:"Shohel",slug:"m.-mahruf-c.-shohel",fullName:"M. Mahruf C. Shohel"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}]},subject:{topic:{id:"811",title:"Aerodynamics",slug:"mechanical-engineering-aerodynamics",parent:{id:"121",title:"Mechanical Engineering",slug:"mechanical-engineering"},numberOfBooks:6,numberOfSeries:0,numberOfAuthorsAndEditors:176,numberOfWosCitations:343,numberOfCrossrefCitations:146,numberOfDimensionsCitations:363,videoUrl:null,fallbackUrl:null,description:null},booksByTopicFilter:{topicId:"811",sort:"-publishedDate",limit:12,offset:0},booksByTopicCollection:[{type:"book",id:"3103",title:"Wind Tunnel Designs and Their Diverse Engineering Applications",subtitle:null,isOpenForSubmission:!1,hash:"969fb2c4bc90732cdc42039cdbcfb918",slug:"wind-tunnel-designs-and-their-diverse-engineering-applications",bookSignature:"N. A. Ahmed",coverURL:"https://cdn.intechopen.com/books/images_new/3103.jpg",editedByType:"Edited by",editors:[{id:"6371",title:"Dr.",name:"Noor",middleName:null,surname:"Ahmed",slug:"noor-ahmed",fullName:"Noor Ahmed"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"1638",title:"Applied Aerodynamics",subtitle:null,isOpenForSubmission:!1,hash:"27eb26a7a997c26a0f7f47642a10aeef",slug:"applied-aerodynamics",bookSignature:"Jorge Colman Lerner\t and Ulfilas Boldes",coverURL:"https://cdn.intechopen.com/books/images_new/1638.jpg",editedByType:"Edited by",editors:[{id:"27183",title:"Dr.",name:"Jorge",middleName:"León",surname:"Colman Lerner",slug:"jorge-colman-lerner",fullName:"Jorge Colman Lerner"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"1984",title:"Low Reynolds Number",subtitle:"Aerodynamics and Transition",isOpenForSubmission:!1,hash:"e2923b28921b17449df4824489b720f2",slug:"low-reynolds-number-aerodynamics-and-transition",bookSignature:"Mustafa Serdar Genc",coverURL:"https://cdn.intechopen.com/books/images_new/1984.jpg",editedByType:"Edited by",editors:[{id:"12039",title:"Dr.",name:"Mustafa Serdar",middleName:null,surname:"Genç",slug:"mustafa-serdar-genc",fullName:"Mustafa Serdar Genç"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"301",title:"Advances in Gas Turbine Technology",subtitle:null,isOpenForSubmission:!1,hash:"88bcc4f8023a33a5f3c1a666af77bb59",slug:"advances-in-gas-turbine-technology",bookSignature:"Ernesto Benini",coverURL:"https://cdn.intechopen.com/books/images_new/301.jpg",editedByType:"Edited by",editors:[{id:"11393",title:"Dr.",name:"Ernesto",middleName:null,surname:"Benini",slug:"ernesto-benini",fullName:"Ernesto Benini"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"204",title:"Wind Tunnels and Experimental Fluid Dynamics Research",subtitle:null,isOpenForSubmission:!1,hash:"9669a7f1e73298e4bf9618e7d2807be3",slug:"wind-tunnels-and-experimental-fluid-dynamics-research",bookSignature:"Jorge Colman Lerner and Ulfilas Boldes",coverURL:"https://cdn.intechopen.com/books/images_new/204.jpg",editedByType:"Edited by",editors:[{id:"27183",title:"Dr.",name:"Jorge",middleName:"León",surname:"Colman Lerner",slug:"jorge-colman-lerner",fullName:"Jorge Colman Lerner"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"114",title:"Wind Tunnels",subtitle:null,isOpenForSubmission:!1,hash:null,slug:"wind-tunnels",bookSignature:"Satoru Okamoto",coverURL:"https://cdn.intechopen.com/books/images_new/114.jpg",editedByType:"Edited by",editors:[{id:"18378",title:"Emeritus Prof.",name:"Satoru",middleName:null,surname:"Okamoto",slug:"satoru-okamoto",fullName:"Satoru Okamoto"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],booksByTopicTotal:6,seriesByTopicCollection:[],seriesByTopicTotal:0,mostCitedChapters:[{id:"22905",doi:"10.5772/20730",title:"Materials for Gas Turbines – An Overview",slug:"materials-for-gas-turbines-an-overview",totalDownloads:48905,totalCrossrefCites:12,totalDimensionsCites:45,abstract:null,book:{id:"301",slug:"advances-in-gas-turbine-technology",title:"Advances in Gas Turbine Technology",fullTitle:"Advances in Gas Turbine Technology"},signatures:"Nageswara Rao Muktinutalapati",authors:[{id:"40270",title:"Prof.",name:"Nageswara Rao",middleName:null,surname:"Muktinutalapati",slug:"nageswara-rao-muktinutalapati",fullName:"Nageswara Rao Muktinutalapati"}]},{id:"34754",doi:"10.5772/31131",title:"Low Reynolds Number Flows and Transition",slug:"low-reynolds-number-flows-and-transition",totalDownloads:8210,totalCrossrefCites:5,totalDimensionsCites:30,abstract:null,book:{id:"1984",slug:"low-reynolds-number-aerodynamics-and-transition",title:"Low Reynolds Number",fullTitle:"Low Reynolds Number Aerodynamics and Transition"},signatures:"M. Serdar Genç, İlyas Karasu, H. Hakan Açıkel and M. Tuğrul Akpolat",authors:[{id:"12039",title:"Dr.",name:"Mustafa Serdar",middleName:null,surname:"Genç",slug:"mustafa-serdar-genc",fullName:"Mustafa Serdar Genç"}]},{id:"22910",doi:"10.5772/21278",title:"BLISK Fabrication by Linear Friction Welding",slug:"blisk-fabrication-by-linear-friction-welding",totalDownloads:8238,totalCrossrefCites:9,totalDimensionsCites:29,abstract:null,book:{id:"301",slug:"advances-in-gas-turbine-technology",title:"Advances in Gas Turbine Technology",fullTitle:"Advances in Gas Turbine Technology"},signatures:"Antonio M. Mateo García",authors:[{id:"42545",title:"Prof.",name:"Antonio Manuel",middleName:null,surname:"Mateo García",slug:"antonio-manuel-mateo-garcia",fullName:"Antonio Manuel Mateo García"}]},{id:"42327",doi:"10.5772/54169",title:"Design Methodology for a Quick and Low-Cost Wind Tunnel",slug:"design-methodology-for-a-quick-and-low-cost-wind-tunnel",totalDownloads:12112,totalCrossrefCites:10,totalDimensionsCites:18,abstract:null,book:{id:"3103",slug:"wind-tunnel-designs-and-their-diverse-engineering-applications",title:"Wind Tunnel Designs and Their Diverse Engineering Applications",fullTitle:"Wind Tunnel Designs and Their Diverse Engineering Applications"},signatures:"Miguel A. González Hernández, Ana I. Moreno López, Artur A. Jarzabek, José M. Perales Perales, Yuliang Wu and Sun Xiaoxiao",authors:[{id:"43510",title:"Prof.",name:"Miguel",middleName:"Angel",surname:"Gonzalez",slug:"miguel-gonzalez",fullName:"Miguel Gonzalez"}]},{id:"22893",doi:"10.5772/19689",title:"Future Aero Engine Designs: An Evolving Vision",slug:"future-aero-engine-designs-an-evolving-vision",totalDownloads:7847,totalCrossrefCites:5,totalDimensionsCites:17,abstract:null,book:{id:"301",slug:"advances-in-gas-turbine-technology",title:"Advances in Gas Turbine Technology",fullTitle:"Advances in Gas Turbine Technology"},signatures:"Konstantinos G. Kyprianidis",authors:[{id:"35868",title:"Prof.",name:"Konstantinos",middleName:"G.",surname:"Kyprianidis",slug:"konstantinos-kyprianidis",fullName:"Konstantinos Kyprianidis"}]}],mostDownloadedChaptersLast30Days:[{id:"42327",title:"Design Methodology for a Quick and Low-Cost Wind Tunnel",slug:"design-methodology-for-a-quick-and-low-cost-wind-tunnel",totalDownloads:12112,totalCrossrefCites:10,totalDimensionsCites:18,abstract:null,book:{id:"3103",slug:"wind-tunnel-designs-and-their-diverse-engineering-applications",title:"Wind Tunnel Designs and Their Diverse Engineering Applications",fullTitle:"Wind Tunnel Designs and Their Diverse Engineering Applications"},signatures:"Miguel A. González Hernández, Ana I. Moreno López, Artur A. Jarzabek, José M. Perales Perales, Yuliang Wu and Sun Xiaoxiao",authors:[{id:"43510",title:"Prof.",name:"Miguel",middleName:"Angel",surname:"Gonzalez",slug:"miguel-gonzalez",fullName:"Miguel Gonzalez"}]},{id:"22905",title:"Materials for Gas Turbines – An Overview",slug:"materials-for-gas-turbines-an-overview",totalDownloads:48905,totalCrossrefCites:12,totalDimensionsCites:45,abstract:null,book:{id:"301",slug:"advances-in-gas-turbine-technology",title:"Advances in Gas Turbine Technology",fullTitle:"Advances in Gas Turbine Technology"},signatures:"Nageswara Rao Muktinutalapati",authors:[{id:"40270",title:"Prof.",name:"Nageswara Rao",middleName:null,surname:"Muktinutalapati",slug:"nageswara-rao-muktinutalapati",fullName:"Nageswara Rao Muktinutalapati"}]},{id:"36821",title:"Aerodynamic Design of Sports Garments",slug:"aerodynamic-design-of-sports-garments",totalDownloads:3556,totalCrossrefCites:4,totalDimensionsCites:6,abstract:null,book:{id:"1638",slug:"applied-aerodynamics",title:"Applied Aerodynamics",fullTitle:"Applied Aerodynamics"},signatures:"Harun Chowdhury",authors:[{id:"118540",title:"Dr.",name:"Harun",middleName:null,surname:"Chowdhury",slug:"harun-chowdhury",fullName:"Harun Chowdhury"}]},{id:"16897",title:"The Importance of Turbulence Reduction in Assessment of Wind Tunnel Flow Quality",slug:"the-importance-of-turbulence-reduction-in-assessment-of-wind-tunnel-flow-quality",totalDownloads:7527,totalCrossrefCites:2,totalDimensionsCites:8,abstract:null,book:{id:"204",slug:"wind-tunnels-and-experimental-fluid-dynamics-research",title:"Wind Tunnels and Experimental Fluid Dynamics Research",fullTitle:"Wind Tunnels and Experimental Fluid Dynamics Research"},signatures:"Mojtaba Dehghan Manshadi",authors:[{id:"27162",title:"Dr.",name:"Mojtaba",middleName:null,surname:"Dehghan Manshadi",slug:"mojtaba-dehghan-manshadi",fullName:"Mojtaba Dehghan Manshadi"}]},{id:"16670",title:"Components of a Wind Tunnel Balance: Design and Calibration",slug:"components-of-a-wind-tunnel-balance-design-and-calibration",totalDownloads:10580,totalCrossrefCites:5,totalDimensionsCites:8,abstract:null,book:{id:"204",slug:"wind-tunnels-and-experimental-fluid-dynamics-research",title:"Wind Tunnels and Experimental Fluid Dynamics Research",fullTitle:"Wind Tunnels and Experimental Fluid Dynamics Research"},signatures:"Miguel Gonzalez, Jose Miguel Ezquerro, Victoria Lapuerta, Ana Laveron and Jacobo Rodriguez",authors:[{id:"43510",title:"Prof.",name:"Miguel",middleName:"Angel",surname:"Gonzalez",slug:"miguel-gonzalez",fullName:"Miguel Gonzalez"},{id:"41750",title:"Prof.",name:"Victoria",middleName:null,surname:"lapuerta",slug:"victoria-lapuerta",fullName:"Victoria lapuerta"},{id:"43511",title:"Prof.",name:"Ana",middleName:null,surname:"Laveron",slug:"ana-laveron",fullName:"Ana Laveron"},{id:"43512",title:"Mr.",name:"Jacobo",middleName:null,surname:"Rodriguez",slug:"jacobo-rodriguez",fullName:"Jacobo Rodriguez"},{id:"44581",title:"Mr",name:"Jose Miguel",middleName:null,surname:"Ezquerro",slug:"jose-miguel-ezquerro",fullName:"Jose Miguel Ezquerro"}]}],onlineFirstChaptersFilter:{topicId:"811",limit:6,offset:0},onlineFirstChaptersCollection:[],onlineFirstChaptersTotal:0},preDownload:{success:null,errors:{}},subscriptionForm:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[],offset:0,limit:8,total:null},allSeries:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:9,numberOfPublishedChapters:87,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:98,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:27,numberOfPublishedChapters:288,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:9,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:11,numberOfPublishedChapters:139,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:8,numberOfPublishedChapters:129,numberOfOpenTopics:0,numberOfUpcomingTopics:2,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!1},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:107,numberOfOpenTopics:3,numberOfUpcomingTopics:1,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:10,numberOfPublishedChapters:103,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:12,numberOfOpenTopics:2,numberOfUpcomingTopics:1,issn:"2753-894X",doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:0,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!1},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:0,numberOfPublishedChapters:11,numberOfOpenTopics:4,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],testimonialsList:[{id:"6",text:"It is great to work with the IntechOpen to produce a worthwhile collection of research that also becomes a great educational resource and guide for future research endeavors.",author:{id:"259298",name:"Edward",surname:"Narayan",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259298/images/system/259298.jpeg",slug:"edward-narayan",institution:{id:"3",name:"University of Queensland",country:{id:null,name:"Australia"}}}},{id:"13",text:"The collaboration with and support of the technical staff of IntechOpen is fantastic. The whole process of submitting an article and editing of the submitted article goes extremely smooth and fast, the number of reads and downloads of chapters is high, and the contributions are also frequently cited.",author:{id:"55578",name:"Antonio",surname:"Jurado-Navas",institutionString:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRisIQAS/Profile_Picture_1626166543950",slug:"antonio-jurado-navas",institution:{id:"720",name:"University of Malaga",country:{id:null,name:"Spain"}}}}]},series:{item:{id:"11",title:"Biochemistry",doi:"10.5772/intechopen.72877",issn:"2632-0983",scope:"Biochemistry, the study of chemical transformations occurring within living organisms, impacts all areas of life sciences, from molecular crystallography and genetics to ecology, medicine, and population biology. Biochemistry examines macromolecules - proteins, nucleic acids, carbohydrates, and lipids – and their building blocks, structures, functions, and interactions. Much of biochemistry is devoted to enzymes, proteins that catalyze chemical reactions, enzyme structures, mechanisms of action and their roles within cells. Biochemistry also studies small signaling molecules, coenzymes, inhibitors, vitamins, and hormones, which play roles in life processes. Biochemical experimentation, besides coopting classical chemistry methods, e.g., chromatography, adopted new techniques, e.g., X-ray diffraction, electron microscopy, NMR, radioisotopes, and developed sophisticated microbial genetic tools, e.g., auxotroph mutants and their revertants, fermentation, etc. More recently, biochemistry embraced the ‘big data’ omics systems. Initial biochemical studies have been exclusively analytic: dissecting, purifying, and examining individual components of a biological system; in the apt words of Efraim Racker (1913 –1991), “Don’t waste clean thinking on dirty enzymes.” Today, however, biochemistry is becoming more agglomerative and comprehensive, setting out to integrate and describe entirely particular biological systems. The ‘big data’ metabolomics can define the complement of small molecules, e.g., in a soil or biofilm sample; proteomics can distinguish all the comprising proteins, e.g., serum; metagenomics can identify all the genes in a complex environment, e.g., the bovine rumen. This Biochemistry Series will address the current research on biomolecules and the emerging trends with great promise.",coverUrl:"https://cdn.intechopen.com/series/covers/11.jpg",latestPublicationDate:"May 24th, 2022",hasOnlineFirst:!0,numberOfPublishedBooks:27,editor:{id:"31610",title:"Dr.",name:"Miroslav",middleName:null,surname:"Blumenberg",slug:"miroslav-blumenberg",fullName:"Miroslav Blumenberg",profilePictureURL:"https://mts.intechopen.com/storage/users/31610/images/system/31610.jpg",biography:"Miroslav Blumenberg, Ph.D., was born in Subotica and received his BSc in Belgrade, Yugoslavia. He completed his Ph.D. at MIT in Organic Chemistry; he followed up his Ph.D. with two postdoctoral study periods at Stanford University. Since 1983, he has been a faculty member of the RO Perelman Department of Dermatology, NYU School of Medicine, where he is codirector of a training grant in cutaneous biology. Dr. Blumenberg’s research is focused on the epidermis, expression of keratin genes, transcription profiling, keratinocyte differentiation, inflammatory diseases and cancers, and most recently the effects of the microbiome on the skin. He has published more than 100 peer-reviewed research articles and graduated numerous Ph.D. and postdoctoral students.",institutionString:null,institution:{name:"New York University Langone Medical Center",institutionURL:null,country:{name:"United States of America"}}},editorTwo:null,editorThree:null},subseries:{paginationCount:9,paginationItems:[{id:"14",title:"Cell and Molecular Biology",coverUrl:"https://cdn.intechopen.com/series_topics/covers/14.jpg",editor:{id:"165627",title:"Dr.",name:"Rosa María",middleName:null,surname:"Martínez-Espinosa",slug:"rosa-maria-martinez-espinosa",fullName:"Rosa María Martínez-Espinosa",profilePictureURL:"https://mts.intechopen.com/storage/users/165627/images/system/165627.jpeg",biography:"Dr. Rosa María Martínez-Espinosa has been a Spanish Full Professor since 2020 (Biochemistry and Molecular Biology) and is currently Vice-President of International Relations and Cooperation development and leader of the research group 'Applied Biochemistry” (University of Alicante, Spain). Other positions she has held at the university include Vice-Dean of Master Programs, Vice-Dean of the Degree in Biology and Vice-Dean for Mobility and Enterprise and Engagement at the Faculty of Science (University of Alicante). She received her Bachelor in Biology in 1998 (University of Alicante) and her PhD in 2003 (Biochemistry, University of Alicante). She undertook post-doctoral research at the University of East Anglia (Norwich, U.K. 2004-2005; 2007-2008).\nHer multidisciplinary research focuses on investigating archaea and their potential applications in biotechnology. She has an H-index of 21. She has authored one patent and has published more than 70 indexed papers and around 60 book chapters.\nShe has contributed to more than 150 national and international meetings during the last 15 years. Her research interests include archaea metabolism, enzymes purification and characterization, gene regulation, carotenoids and bioplastics production, antioxidant\ncompounds, waste water treatments, and brines bioremediation.\nRosa María’s other roles include editorial board member for several journals related\nto biochemistry, reviewer for more than 60 journals (biochemistry, molecular biology, biotechnology, chemistry and microbiology) and president of several organizing committees in international meetings related to the N-cycle or respiratory processes.",institutionString:null,institution:{name:"University of Alicante",institutionURL:null,country:{name:"Spain"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"79367",title:"Dr.",name:"Ana Isabel",middleName:null,surname:"Flores",slug:"ana-isabel-flores",fullName:"Ana Isabel Flores",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRpIOQA0/Profile_Picture_1632418099564",institutionString:null,institution:{name:"Hospital Universitario 12 De Octubre",institutionURL:null,country:{name:"Spain"}}},{id:"328234",title:"Ph.D.",name:"Christian",middleName:null,surname:"Palavecino",slug:"christian-palavecino",fullName:"Christian Palavecino",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000030DhEhQAK/Profile_Picture_1628835318625",institutionString:null,institution:{name:"Central University of Chile",institutionURL:null,country:{name:"Chile"}}},{id:"186585",title:"Dr.",name:"Francisco Javier",middleName:null,surname:"Martin-Romero",slug:"francisco-javier-martin-romero",fullName:"Francisco Javier Martin-Romero",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSB3HQAW/Profile_Picture_1631258137641",institutionString:null,institution:{name:"University of Extremadura",institutionURL:null,country:{name:"Spain"}}}]},{id:"15",title:"Chemical Biology",coverUrl:"https://cdn.intechopen.com/series_topics/covers/15.jpg",editor:{id:"441442",title:"Dr.",name:"Şükrü",middleName:null,surname:"Beydemir",slug:"sukru-beydemir",fullName:"Şükrü Beydemir",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00003GsUoIQAV/Profile_Picture_1634557147521",biography:"Dr. Şükrü Beydemir obtained a BSc in Chemistry in 1995 from Yüzüncü Yıl University, MSc in Biochemistry in 1998, and PhD in Biochemistry in 2002 from Atatürk University, Turkey. He performed post-doctoral studies at Max-Planck Institute, Germany, and University of Florence, Italy in addition to making several scientific visits abroad. He currently works as a Full Professor of Biochemistry in the Faculty of Pharmacy, Anadolu University, Turkey. Dr. Beydemir has published over a hundred scientific papers spanning protein biochemistry, enzymology and medicinal chemistry, reviews, book chapters and presented several conferences to scientists worldwide. He has received numerous publication awards from various international scientific councils. He serves in the Editorial Board of several international journals. Dr. Beydemir is also Rector of Bilecik Şeyh Edebali University, Turkey.",institutionString:null,institution:{name:"Anadolu University",institutionURL:null,country:{name:"Turkey"}}},editorTwo:{id:"13652",title:"Prof.",name:"Deniz",middleName:null,surname:"Ekinci",slug:"deniz-ekinci",fullName:"Deniz Ekinci",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYLT1QAO/Profile_Picture_1634557223079",biography:"Dr. Deniz Ekinci obtained a BSc in Chemistry in 2004, MSc in Biochemistry in 2006, and PhD in Biochemistry in 2009 from Atatürk University, Turkey. He studied at Stetson University, USA, in 2007-2008 and at the Max Planck Institute of Molecular Cell Biology and Genetics, Germany, in 2009-2010. Dr. Ekinci currently works as a Full Professor of Biochemistry in the Faculty of Agriculture and is the Head of the Enzyme and Microbial Biotechnology Division, Ondokuz Mayıs University, Turkey. He is a member of the Turkish Biochemical Society, American Chemical Society, and German Genetics society. Dr. Ekinci published around ninety scientific papers, reviews and book chapters, and presented several conferences to scientists. He has received numerous publication awards from several scientific councils. Dr. Ekinci serves as the Editor in Chief of four international books and is involved in the Editorial Board of several international journals.",institutionString:null,institution:{name:"Ondokuz Mayıs University",institutionURL:null,country:{name:"Turkey"}}},editorThree:null,editorialBoard:[{id:"241413",title:"Dr.",name:"Azhar",middleName:null,surname:"Rasul",slug:"azhar-rasul",fullName:"Azhar Rasul",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRT1oQAG/Profile_Picture_1635251978933",institutionString:null,institution:{name:"Government College University, Faisalabad",institutionURL:null,country:{name:"Pakistan"}}},{id:"178316",title:"Ph.D.",name:"Sergey",middleName:null,surname:"Sedykh",slug:"sergey-sedykh",fullName:"Sergey Sedykh",profilePictureURL:"https://mts.intechopen.com/storage/users/178316/images/system/178316.jfif",institutionString:null,institution:{name:"Novosibirsk State University",institutionURL:null,country:{name:"Russia"}}}]},{id:"17",title:"Metabolism",coverUrl:"https://cdn.intechopen.com/series_topics/covers/17.jpg",editor:{id:"138626",title:"Dr.",name:"Yannis",middleName:null,surname:"Karamanos",slug:"yannis-karamanos",fullName:"Yannis Karamanos",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002g6Jv2QAE/Profile_Picture_1629356660984",biography:"Yannis Karamanos, born in Greece in 1953, completed his pre-graduate studies at the Université Pierre et Marie Curie, Paris, then his Masters and Doctoral degree at the Université de Lille (1983). He was associate professor at the University of Limoges (1987) before becoming full professor of biochemistry at the Université d’Artois (1996). He worked on the structure-function relationships of glycoconjugates and his main project was the investigations on the biological roles of the de-N-glycosylation enzymes (Endo-N-acetyl-β-D-glucosaminidase and peptide-N4-(N-acetyl-β-glucosaminyl) asparagine amidase). From 2002 he contributes to the understanding of the Blood-brain barrier functioning using proteomics approaches. He has published more than 70 papers. His teaching areas are energy metabolism and regulation, integration and organ specialization and metabolic adaptation.",institutionString:null,institution:{name:"Artois University",institutionURL:null,country:{name:"France"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"243049",title:"Dr.",name:"Anca",middleName:null,surname:"Pantea Stoian",slug:"anca-pantea-stoian",fullName:"Anca Pantea Stoian",profilePictureURL:"https://mts.intechopen.com/storage/users/243049/images/system/243049.jpg",institutionString:null,institution:{name:"Carol Davila University of Medicine and Pharmacy",institutionURL:null,country:{name:"Romania"}}},{id:"203824",title:"Dr.",name:"Attilio",middleName:null,surname:"Rigotti",slug:"attilio-rigotti",fullName:"Attilio Rigotti",profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institutionString:null,institution:{name:"Pontifical Catholic University of Chile",institutionURL:null,country:{name:"Chile"}}},{id:"300470",title:"Dr.",name:"Yanfei (Jacob)",middleName:null,surname:"Qi",slug:"yanfei-(jacob)-qi",fullName:"Yanfei (Jacob) Qi",profilePictureURL:"https://mts.intechopen.com/storage/users/300470/images/system/300470.jpg",institutionString:null,institution:{name:"Centenary Institute of Cancer Medicine and Cell Biology",institutionURL:null,country:{name:"Australia"}}}]},{id:"18",title:"Proteomics",coverUrl:"https://cdn.intechopen.com/series_topics/covers/18.jpg",editor:{id:"200689",title:"Prof.",name:"Paolo",middleName:null,surname:"Iadarola",slug:"paolo-iadarola",fullName:"Paolo Iadarola",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSCl8QAG/Profile_Picture_1623568118342",biography:"Paolo Iadarola graduated with a degree in Chemistry from the University of Pavia (Italy) in July 1972. He then worked as an Assistant Professor at the Faculty of Science of the same University until 1984. In 1985, Prof. Iadarola became Associate Professor at the Department of Biology and Biotechnologies of the University of Pavia and retired in October 2017. Since then, he has been working as an Adjunct Professor in the same Department at the University of Pavia. His research activity during the first years was primarily focused on the purification and structural characterization of enzymes from animal and plant sources. During this period, Prof. Iadarola familiarized himself with the conventional techniques used in column chromatography, spectrophotometry, manual Edman degradation, and electrophoresis). Since 1995, he has been working on: i) the determination in biological fluids (serum, urine, bronchoalveolar lavage, sputum) of proteolytic activities involved in the degradation processes of connective tissue matrix, and ii) on the identification of biological markers of lung diseases. In this context, he has developed and validated new methodologies (e.g., Capillary Electrophoresis coupled to Laser-Induced Fluorescence, CE-LIF) whose application enabled him to determine both the amounts of biochemical markers (Desmosines) in urine/serum of patients affected by Chronic Obstructive Pulmonary Disease (COPD) and the activity of proteolytic enzymes (Human Neutrophil Elastase, Cathepsin G, Pseudomonas aeruginosa elastase) in sputa of these patients. More recently, Prof. Iadarola was involved in developing techniques such as two-dimensional electrophoresis coupled to liquid chromatography/mass spectrometry (2DE-LC/MS) for the proteomic analysis of biological fluids aimed at the identification of potential biomarkers of different lung diseases. He is the author of about 150 publications (According to Scopus: H-Index: 23; Total citations: 1568- According to WOS: H-Index: 20; Total Citations: 1296) of peer-reviewed international journals. He is a Consultant Reviewer for several journals, including the Journal of Chromatography A, Journal of Chromatography B, Plos ONE, Proteomes, International Journal of Molecular Science, Biotech, Electrophoresis, and others. He is also Associate Editor of Biotech.",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorTwo:{id:"201414",title:"Dr.",name:"Simona",middleName:null,surname:"Viglio",slug:"simona-viglio",fullName:"Simona Viglio",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRKDHQA4/Profile_Picture_1630402531487",biography:"Simona Viglio is an Associate Professor of Biochemistry at the Department of Molecular Medicine at the University of Pavia. She has been working since 1995 on the determination of proteolytic enzymes involved in the degradation process of connective tissue matrix and on the identification of biological markers of lung diseases. She gained considerable experience in developing and validating new methodologies whose applications allowed her to determine both the amount of biomarkers (Desmosine and Isodesmosine) in the urine of patients affected by COPD, and the activity of proteolytic enzymes (HNE, Cathepsin G, Pseudomonas aeruginosa elastase) in the sputa of these patients. Simona Viglio was also involved in research dealing with the supplementation of amino acids in patients with brain injury and chronic heart failure. She is presently engaged in the development of 2-DE and LC-MS techniques for the study of proteomics in biological fluids. The aim of this research is the identification of potential biomarkers of lung diseases. She is an author of about 90 publications (According to Scopus: H-Index: 23; According to WOS: H-Index: 20) on peer-reviewed journals, a member of the “Società Italiana di Biochimica e Biologia Molecolare,“ and a Consultant Reviewer for International Journal of Molecular Science, Journal of Chromatography A, COPD, Plos ONE and Nutritional Neuroscience.",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorThree:null,editorialBoard:[{id:"72288",title:"Dr.",name:"Arli Aditya",middleName:null,surname:"Parikesit",slug:"arli-aditya-parikesit",fullName:"Arli Aditya Parikesit",profilePictureURL:"https://mts.intechopen.com/storage/users/72288/images/system/72288.jpg",institutionString:null,institution:{name:"Indonesia International Institute for Life Sciences",institutionURL:null,country:{name:"Indonesia"}}},{id:"40928",title:"Dr.",name:"Cesar",middleName:null,surname:"Lopez-Camarillo",slug:"cesar-lopez-camarillo",fullName:"Cesar Lopez-Camarillo",profilePictureURL:"https://mts.intechopen.com/storage/users/40928/images/3884_n.png",institutionString:null,institution:{name:"Universidad Autónoma de la Ciudad de México",institutionURL:null,country:{name:"Mexico"}}},{id:"81926",title:"Dr.",name:"Shymaa",middleName:null,surname:"Enany",slug:"shymaa-enany",fullName:"Shymaa Enany",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRqB9QAK/Profile_Picture_1626163237970",institutionString:null,institution:{name:"Suez Canal University",institutionURL:null,country:{name:"Egypt"}}}]}]},overviewPageOFChapters:{paginationCount:0,paginationItems:[]},overviewPagePublishedBooks:{paginationCount:1,paginationItems:[{type:"book",id:"10843",title:"Persistent Organic Pollutants (POPs)",subtitle:"Monitoring, Impact and Treatment",coverURL:"https://cdn.intechopen.com/books/images_new/10843.jpg",slug:"persistent-organic-pollutants-pops-monitoring-impact-and-treatment",publishedDate:"April 13th 2022",editedByType:"Edited by",bookSignature:"Mohamed Nageeb Rashed",hash:"f5b1589f0a990b6114fef2dadc735dd9",volumeInSeries:1,fullTitle:"Persistent Organic Pollutants (POPs) - Monitoring, Impact and Treatment",editors:[{id:"63465",title:"Prof.",name:"Mohamed Nageeb",middleName:null,surname:"Rashed",slug:"mohamed-nageeb-rashed",fullName:"Mohamed Nageeb Rashed",profilePictureURL:"https://mts.intechopen.com/storage/users/63465/images/system/63465.gif",biography:"Prof. Mohamed Nageeb Rashed is Professor of Analytical and Environmental Chemistry and former vice-dean for environmental affairs, Faculty of Science, Aswan University, Egypt. He received his Ph.D. in Environmental Analytical Chemistry from Assiut University, Egypt, in 1989. His research interest is in analytical and environmental chemistry with special emphasis on: (1) monitoring and assessing biological trace elements and toxic metals in human blood, urine, water, crops, vegetables, and medicinal plants; (2) relationships between environmental heavy metals and human diseases; (3) uses of biological indicators for monitoring water pollution; (4) environmental chemistry of lakes, rivers, and well water; (5) water and wastewater treatment by adsorption and photocatalysis techniques; (6) soil and water pollution monitoring, control, and treatment; and (7) advanced oxidation treatment. Prof. Rashed has supervised several MSc and Ph.D. theses in the field of analytical and environmental chemistry. He served as an examiner for several Ph.D. theses in analytical chemistry in India, Kazakhstan, and Botswana. He has published about ninety scientific papers in peer-reviewed international journals and several papers in national and international conferences. He participated as an invited speaker at thirty international conferences. Prof. Rashed is the editor-in-chief and an editorial board member for several international journals in the fields of chemistry and environment. He is a member of several national and international societies. He received the Egyptian State Award for Environmental Research in 2001 and the Aswan University Merit Award for Basic Science in 2020. Prof. Rashed was recognized in Stanford University’s list of the World’s Top 2% Scientists in 2020 and 2021.",institutionString:null,institution:{name:"Aswan University",institutionURL:null,country:{name:"Egypt"}}}]}]},openForSubmissionBooks:{},onlineFirstChapters:{paginationCount:43,paginationItems:[{id:"81796",title:"Apoptosis-Related Diseases and Peroxisomes",doi:"10.5772/intechopen.105052",signatures:"Meimei Wang, Yakun Liu, Ni Chen, Juan Wang and Ye Zhao",slug:"apoptosis-related-diseases-and-peroxisomes",totalDownloads:3,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"The Metabolic Role of Peroxisome in Health and Disease",coverURL:"https://cdn.intechopen.com/books/images_new/10837.jpg",subseries:{id:"11",title:"Cell Physiology"}}},{id:"81723",title:"Peroxisomal Modulation as Therapeutic Alternative for Tackling Multiple Cancers",doi:"10.5772/intechopen.104873",signatures:"Shazia Usmani, Shadma Wahab, Abdul Hafeez, Shabana Khatoon and Syed Misbahul Hasan",slug:"peroxisomal-modulation-as-therapeutic-alternative-for-tackling-multiple-cancers",totalDownloads:3,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"The Metabolic Role of Peroxisome in Health and Disease",coverURL:"https://cdn.intechopen.com/books/images_new/10837.jpg",subseries:{id:"11",title:"Cell Physiology"}}},{id:"81638",title:"Aging and Neuropsychiatric Disease: A General Overview of Prevalence and Trends",doi:"10.5772/intechopen.103102",signatures:"Jelena Milić",slug:"aging-and-neuropsychiatric-disease-a-general-overview-of-prevalence-and-trends",totalDownloads:14,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Senescence",coverURL:"https://cdn.intechopen.com/books/images_new/10935.jpg",subseries:{id:"11",title:"Cell Physiology"}}},{id:"81566",title:"New and Emerging Technologies for Integrative Ambulatory Autonomic Assessment and Intervention as a Catalyst in the Synergy of Remote Geocoded Biosensing, Algorithmic Networked Cloud Computing, Deep Learning, and Regenerative/Biomic Medicine: Further Real",doi:"10.5772/intechopen.104092",signatures:"Robert L. Drury",slug:"new-and-emerging-technologies-for-integrative-ambulatory-autonomic-assessment-and-intervention-as-a-",totalDownloads:9,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Autonomic Nervous System - Special Interest Topics",coverURL:"https://cdn.intechopen.com/books/images_new/10835.jpg",subseries:{id:"12",title:"Human Physiology"}}},{id:"81576",title:"Carotenoids in Thermal Adaptation of Plants and Animals",doi:"10.5772/intechopen.104537",signatures:"Ivan M. Petyaev",slug:"carotenoids-in-thermal-adaptation-of-plants-and-animals",totalDownloads:18,totalCrossrefCites:0,totalDimensionsCites:0,authors:[{name:"Ivan",surname:"Petyaev"}],book:{title:"Carotenoids - New Perspectives and Application",coverURL:"https://cdn.intechopen.com/books/images_new/10836.jpg",subseries:{id:"13",title:"Plant Physiology"}}},{id:"81358",title:"New Insights on Carotenoid Production by Gordonia alkanivorans Strain 1B",doi:"10.5772/intechopen.103919",signatures:"Tiago P. Silva, Susana M. Paixão, Ana S. Fernandes, José C. Roseiro and Luís Alves",slug:"new-insights-on-carotenoid-production-by-gordonia-alkanivorans-strain-1b",totalDownloads:13,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Carotenoids - New Perspectives and Application",coverURL:"https://cdn.intechopen.com/books/images_new/10836.jpg",subseries:{id:"13",title:"Plant Physiology"}}},{id:"81298",title:"Roles of Extracellular Vesicles in Cancer Metastasis",doi:"10.5772/intechopen.103798",signatures:"Eman Helmy Thabet",slug:"roles-of-extracellular-vesicles-in-cancer-metastasis",totalDownloads:20,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Extracellular Vesicles - Role in Diseases, Pathogenesis and Therapy",coverURL:"https://cdn.intechopen.com/books/images_new/10796.jpg",subseries:{id:"11",title:"Cell Physiology"}}},{id:"81290",title:"Musculoskeletal Abnormalities Caused by Cystic Fibrosis",doi:"10.5772/intechopen.104591",signatures:"Mark Lambrechts",slug:"musculoskeletal-abnormalities-caused-by-cystic-fibrosis",totalDownloads:13,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Advances in Skeletal Muscle Health and Disease",coverURL:"https://cdn.intechopen.com/books/images_new/11675.jpg",subseries:{id:"11",title:"Cell Physiology"}}},{id:"81286",title:"Potassium Derangements: A Pathophysiological Review, Diagnostic Approach, and Clinical Management",doi:"10.5772/intechopen.103016",signatures:"Sairah Sharif and Jie Tang",slug:"potassium-derangements-a-pathophysiological-review-diagnostic-approach-and-clinical-management",totalDownloads:25,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Potassium in Human Health",coverURL:"https://cdn.intechopen.com/books/images_new/10794.jpg",subseries:{id:"12",title:"Human Physiology"}}},{id:"81246",title:"Role of Carotenoids in Cardiovascular Disease",doi:"10.5772/intechopen.102750",signatures:"Arslan Ahmad, Sakhawat Riaz, Muhammad Shahzaib Nadeem, Umber Mubeen and Khadija Maham",slug:"role-of-carotenoids-in-cardiovascular-disease",totalDownloads:27,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Carotenoids - New Perspectives and Application",coverURL:"https://cdn.intechopen.com/books/images_new/10836.jpg",subseries:{id:"13",title:"Plant Physiology"}}}]},subseriesFiltersForOFChapters:[{caption:"Plant Physiology",value:13,count:5,group:"subseries"},{caption:"Human Physiology",value:12,count:13,group:"subseries"},{caption:"Cell Physiology",value:11,count:25,group:"subseries"}],publishedBooks:{paginationCount:10,paginationItems:[{type:"book",id:"10830",title:"Animal Feed Science and Nutrition",subtitle:"Production, Health and Environment",coverURL:"https://cdn.intechopen.com/books/images_new/10830.jpg",slug:"animal-feed-science-and-nutrition-production-health-and-environment",publishedDate:"May 18th 2022",editedByType:"Edited by",bookSignature:"Amlan Kumar Patra",hash:"79944fc8fbbaa329aed6fde388154832",volumeInSeries:10,fullTitle:"Animal Feed Science and Nutrition - Production, Health and Environment",editors:[{id:"310962",title:"Dr.",name:"Amlan",middleName:"Kumar",surname:"Patra",slug:"amlan-patra",fullName:"Amlan Patra",profilePictureURL:"https://mts.intechopen.com/storage/users/310962/images/system/310962.jpg",institutionString:null,institution:{name:"West Bengal University of Animal and Fishery Sciences",institutionURL:null,country:{name:"India"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"8737",title:"Rabies Virus at the Beginning of 21st Century",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/8737.jpg",slug:"rabies-virus-at-the-beginning-of-21st-century",publishedDate:"May 11th 2022",editedByType:"Edited by",bookSignature:"Sergey Tkachev",hash:"49cce3f548da548c718c865feb343509",volumeInSeries:9,fullTitle:"Rabies Virus at the Beginning of 21st Century",editors:[{id:"61139",title:"Dr.",name:"Sergey",middleName:null,surname:"Tkachev",slug:"sergey-tkachev",fullName:"Sergey Tkachev",profilePictureURL:"https://mts.intechopen.com/storage/users/61139/images/system/61139.png",institutionString:"Russian Academy of Sciences",institution:{name:"Russian Academy of Sciences",institutionURL:null,country:{name:"Russia"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"10496",title:"Advanced Studies in the 21st Century Animal Nutrition",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/10496.jpg",slug:"advanced-studies-in-the-21st-century-animal-nutrition",publishedDate:"December 8th 2021",editedByType:"Edited by",bookSignature:"László Babinszky, Juliana Oliveira and Edson Mauro Santos",hash:"8ffe43a82ac48b309abc3632bbf3efd0",volumeInSeries:8,fullTitle:"Advanced Studies in the 21st Century Animal Nutrition",editors:[{id:"53998",title:"Prof.",name:"László",middleName:null,surname:"Babinszky",slug:"laszlo-babinszky",fullName:"László Babinszky",profilePictureURL:"https://mts.intechopen.com/storage/users/53998/images/system/53998.png",institutionString:"University of Debrecen",institution:{name:"University of Debrecen",institutionURL:null,country:{name:"Hungary"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"10497",title:"Canine Genetics, Health and Medicine",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/10497.jpg",slug:"canine-genetics-health-and-medicine",publishedDate:"June 2nd 2021",editedByType:"Edited by",bookSignature:"Catrin Rutland",hash:"b91512e31ce34032e560362e6cbccc1c",volumeInSeries:7,fullTitle:"Canine Genetics, Health and Medicine",editors:[{id:"202192",title:"Dr.",name:"Catrin",middleName:null,surname:"Rutland",slug:"catrin-rutland",fullName:"Catrin Rutland",profilePictureURL:"https://mts.intechopen.com/storage/users/202192/images/system/202192.png",institutionString:null,institution:{name:"University of Nottingham",institutionURL:null,country:{name:"United Kingdom"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"8545",title:"Animal Reproduction in Veterinary Medicine",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/8545.jpg",slug:"animal-reproduction-in-veterinary-medicine",publishedDate:"January 20th 2021",editedByType:"Edited by",bookSignature:"Faruk Aral, Rita Payan-Carreira and Miguel Quaresma",hash:"13aaddf5fdbbc78387e77a7da2388bf6",volumeInSeries:6,fullTitle:"Animal Reproduction in Veterinary Medicine",editors:[{id:"25600",title:"Prof.",name:"Faruk",middleName:null,surname:"Aral",slug:"faruk-aral",fullName:"Faruk Aral",profilePictureURL:"https://mts.intechopen.com/storage/users/25600/images/system/25600.jpg",institutionString:"Independent Researcher",institution:{name:"Harran University",institutionURL:null,country:{name:"Turkey"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"9081",title:"Equine Science",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/9081.jpg",slug:"equine-science",publishedDate:"September 23rd 2020",editedByType:"Edited by",bookSignature:"Catrin Rutland and Albert Rizvanov",hash:"ac415ef2f5450fa80fdb9cf6cf32cd2d",volumeInSeries:5,fullTitle:"Equine Science",editors:[{id:"202192",title:"Dr.",name:"Catrin",middleName:null,surname:"Rutland",slug:"catrin-rutland",fullName:"Catrin Rutland",profilePictureURL:"https://mts.intechopen.com/storage/users/202192/images/system/202192.png",institutionString:null,institution:{name:"University of Nottingham",institutionURL:null,country:{name:"United Kingdom"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"8460",title:"Reproductive Biology and Technology in Animals",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/8460.jpg",slug:"reproductive-biology-and-technology-in-animals",publishedDate:"April 15th 2020",editedByType:"Edited by",bookSignature:"Juan Carlos Gardón Poggi and Katy Satué Ambrojo",hash:"32ef5fe73998dd723d308225d756fa1e",volumeInSeries:4,fullTitle:"Reproductive Biology and Technology in Animals",editors:[{id:"251314",title:"Dr.",name:"Juan Carlos",middleName:null,surname:"Gardón",slug:"juan-carlos-gardon",fullName:"Juan Carlos Gardón",profilePictureURL:"https://mts.intechopen.com/storage/users/251314/images/system/251314.jpeg",institutionString:"Catholic University of Valencia San Vicente Mártir, Spain",institution:null}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"8524",title:"Lactation in Farm Animals",subtitle:"Biology, Physiological Basis, Nutritional Requirements, and Modelization",coverURL:"https://cdn.intechopen.com/books/images_new/8524.jpg",slug:"lactation-in-farm-animals-biology-physiological-basis-nutritional-requirements-and-modelization",publishedDate:"January 22nd 2020",editedByType:"Edited by",bookSignature:"Naceur M'Hamdi",hash:"2aa2a9a0ec13040bbf0455e34625504e",volumeInSeries:3,fullTitle:"Lactation in Farm Animals - Biology, Physiological Basis, Nutritional Requirements, and Modelization",editors:[{id:"73376",title:"Dr.",name:"Naceur",middleName:null,surname:"M'Hamdi",slug:"naceur-m'hamdi",fullName:"Naceur M'Hamdi",profilePictureURL:"https://mts.intechopen.com/storage/users/73376/images/system/73376.jpg",institutionString:null,institution:null}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"7144",title:"Veterinary Anatomy and Physiology",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7144.jpg",slug:"veterinary-anatomy-and-physiology",publishedDate:"March 13th 2019",editedByType:"Edited by",bookSignature:"Catrin Sian Rutland and Valentina Kubale",hash:"75cdacb570e0e6d15a5f6e69640d87c9",volumeInSeries:2,fullTitle:"Veterinary Anatomy and Physiology",editors:[{id:"202192",title:"Dr.",name:"Catrin",middleName:null,surname:"Rutland",slug:"catrin-rutland",fullName:"Catrin Rutland",profilePictureURL:"https://mts.intechopen.com/storage/users/202192/images/system/202192.png",institutionString:null,institution:{name:"University of Nottingham",institutionURL:null,country:{name:"United Kingdom"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"7233",title:"New Insights into Theriogenology",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7233.jpg",slug:"new-insights-into-theriogenology",publishedDate:"December 5th 2018",editedByType:"Edited by",bookSignature:"Rita Payan-Carreira",hash:"74f4147e3fb214dd050e5edd3aaf53bc",volumeInSeries:1,fullTitle:"New Insights into Theriogenology",editors:[{id:"38652",title:"Prof.",name:"Rita",middleName:null,surname:"Payan-Carreira",slug:"rita-payan-carreira",fullName:"Rita Payan-Carreira",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRiFPQA0/Profile_Picture_1614601496313",institutionString:null,institution:{name:"University of Évora",institutionURL:null,country:{name:"Portugal"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null}]},subseriesFiltersForPublishedBooks:[{group:"subseries",caption:"Animal Nutrition",value:20,count:2},{group:"subseries",caption:"Animal Reproductive Biology and Technology",value:28,count:3},{group:"subseries",caption:"Animal Science",value:19,count:5}],publicationYearFilters:[{group:"publicationYear",caption:"2022",value:2022,count:2},{group:"publicationYear",caption:"2021",value:2021,count:3},{group:"publicationYear",caption:"2020",value:2020,count:3},{group:"publicationYear",caption:"2019",value:2019,count:1},{group:"publicationYear",caption:"2018",value:2018,count:1}],authors:{paginationCount:617,paginationItems:[{id:"158492",title:"Prof.",name:"Yusuf",middleName:null,surname:"Tutar",slug:"yusuf-tutar",fullName:"Yusuf Tutar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/158492/images/system/158492.jpeg",biography:"Prof. Dr. Yusuf Tutar conducts his research at the Hamidiye Faculty of Pharmacy, Department of Basic Pharmaceutical Sciences, Division of Biochemistry, University of Health Sciences, Turkey. He is also a faculty member in the Molecular Oncology Program. He obtained his MSc and Ph.D. at Oregon State University and Texas Tech University, respectively. He pursued his postdoctoral studies at Rutgers University Medical School and the National Institutes of Health (NIH/NIDDK), USA. His research focuses on biochemistry, biophysics, genetics, molecular biology, and molecular medicine with specialization in the fields of drug design, protein structure-function, protein folding, prions, microRNA, pseudogenes, molecular cancer, epigenetics, metabolites, proteomics, genomics, protein expression, and characterization by spectroscopic and calorimetric methods.",institutionString:"University of Health Sciences",institution:null},{id:"180528",title:"Dr.",name:"Hiroyuki",middleName:null,surname:"Kagechika",slug:"hiroyuki-kagechika",fullName:"Hiroyuki Kagechika",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/180528/images/system/180528.jpg",biography:"Hiroyuki Kagechika received his bachelor’s degree and Ph.D. in Pharmaceutical Sciences from the University of Tokyo, Japan, where he served as an associate professor until 2004. He is currently a professor at the Institute of Biomaterials and Bioengineering (IBB), Tokyo Medical and Dental University (TMDU). From 2010 to 2012, he was the dean of the Graduate School of Biomedical Science. Since 2012, he has served as the vice dean of the Graduate School of Medical and Dental Sciences. He has been the director of the IBB since 2020. Dr. Kagechika’s major research interests are the medicinal chemistry of retinoids, vitamins D/K, and nuclear receptors. He has developed various compounds including a drug for acute promyelocytic leukemia.",institutionString:"Tokyo Medical and Dental University",institution:{name:"Tokyo Medical and Dental University",country:{name:"Japan"}}},{id:"40482",title:null,name:"Rizwan",middleName:null,surname:"Ahmad",slug:"rizwan-ahmad",fullName:"Rizwan Ahmad",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/40482/images/system/40482.jpeg",biography:"Dr. Rizwan Ahmad is a University Professor and Coordinator, Quality and Development, College of Medicine, Imam Abdulrahman bin Faisal University, Saudi Arabia. Previously, he was Associate Professor of Human Function, Oman Medical College, Oman, and SBS University, Dehradun. Dr. Ahmad completed his education at Aligarh Muslim University, Aligarh. He has published several articles in peer-reviewed journals, chapters, and edited books. His area of specialization is free radical biochemistry and autoimmune diseases.",institutionString:"Imam Abdulrahman Bin Faisal University",institution:{name:"Imam Abdulrahman Bin Faisal University",country:{name:"Saudi Arabia"}}},{id:"41865",title:"Prof.",name:"Farid A.",middleName:null,surname:"Badria",slug:"farid-a.-badria",fullName:"Farid A. Badria",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/41865/images/system/41865.jpg",biography:"Farid A. Badria, Ph.D., is the recipient of several awards, including The World Academy of Sciences (TWAS) Prize for Public Understanding of Science; the World Intellectual Property Organization (WIPO) Gold Medal for best invention; Outstanding Arab Scholar, Kuwait; and the Khwarizmi International Award, Iran. He has 250 publications, 12 books, 20 patents, and several marketed pharmaceutical products to his credit. He continues to lead research projects on developing new therapies for liver, skin disorders, and cancer. Dr. Badria was listed among the world’s top 2% of scientists in medicinal and biomolecular chemistry in 2019 and 2020. He is a member of the Arab Development Fund, Kuwait; International Cell Research Organization–United Nations Educational, Scientific and Cultural Organization (ICRO–UNESCO), Chile; and UNESCO Biotechnology France",institutionString:"Mansoura University",institution:{name:"Mansoura University",country:{name:"Egypt"}}},{id:"329385",title:"Dr.",name:"Rajesh K.",middleName:"Kumar",surname:"Singh",slug:"rajesh-k.-singh",fullName:"Rajesh K. Singh",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/329385/images/system/329385.png",biography:"Dr. Singh received a BPharm (2003) and MPharm (2005) from Panjab University, Chandigarh, India, and a Ph.D. (2013) from Punjab Technical University (PTU), Jalandhar, India. He has more than sixteen years of teaching experience and has supervised numerous postgraduate and Ph.D. students. He has to his credit more than seventy papers in SCI- and SCOPUS-indexed journals, fifty-five conference proceedings, four books, six Best Paper Awards, and five projects from different government agencies. He is currently an editorial board member of eight international journals and a reviewer for more than fifty scientific journals. He received Top Reviewer and Excellent Peer Reviewer Awards from Publons in 2016 and 2017, respectively. He is also on the panel of The International Reviewer for reviewing research proposals for grants from the Royal Society. He also serves as a Publons Academy mentor and Bentham brand ambassador.",institutionString:"Punjab Technical University",institution:{name:"Punjab Technical University",country:{name:"India"}}},{id:"142388",title:"Dr.",name:"Thiago",middleName:"Gomes",surname:"Gomes Heck",slug:"thiago-gomes-heck",fullName:"Thiago Gomes Heck",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/142388/images/7259_n.jpg",biography:null,institutionString:null,institution:{name:"Universidade Regional do Noroeste do Estado do Rio Grande do Sul",country:{name:"Brazil"}}},{id:"336273",title:"Assistant Prof.",name:"Janja",middleName:null,surname:"Zupan",slug:"janja-zupan",fullName:"Janja Zupan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/336273/images/14853_n.jpeg",biography:"Janja Zupan graduated in 2005 at the Department of Clinical Biochemistry (superviser prof. dr. Janja Marc) in the field of genetics of osteoporosis. Since November 2009 she is working as a Teaching Assistant at the Faculty of Pharmacy, Department of Clinical Biochemistry. In 2011 she completed part of her research and PhD work at Institute of Genetics and Molecular Medicine, University of Edinburgh. She finished her PhD entitled The influence of the proinflammatory cytokines on the RANK/RANKL/OPG in bone tissue of osteoporotic and osteoarthritic patients in 2012. From 2014-2016 she worked at the Institute of Biomedical Sciences, University of Aberdeen as a postdoctoral research fellow on UK Arthritis research project where she gained knowledge in mesenchymal stem cells and regenerative medicine. She returned back to University of Ljubljana, Faculty of Pharmacy in 2016. She is currently leading project entitled Mesenchymal stem cells-the keepers of tissue endogenous regenerative capacity facing up to aging of the musculoskeletal system funded by Slovenian Research Agency.",institutionString:null,institution:{name:"University of Ljubljana",country:{name:"Slovenia"}}},{id:"357453",title:"Dr.",name:"Radheshyam",middleName:null,surname:"Maurya",slug:"radheshyam-maurya",fullName:"Radheshyam Maurya",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/357453/images/16535_n.jpg",biography:null,institutionString:null,institution:{name:"University of Hyderabad",country:{name:"India"}}},{id:"311457",title:"Dr.",name:"Júlia",middleName:null,surname:"Scherer Santos",slug:"julia-scherer-santos",fullName:"Júlia Scherer Santos",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/311457/images/system/311457.jpg",biography:"Dr. Júlia Scherer Santos works in the areas of cosmetology, nanotechnology, pharmaceutical technology, beauty, and aesthetics. Dr. Santos also has experience as a professor of graduate courses. Graduated in Pharmacy, specialization in Cosmetology and Cosmeceuticals applied to aesthetics, specialization in Aesthetic and Cosmetic Health, and a doctorate in Pharmaceutical Nanotechnology. Teaching experience in Pharmacy and Aesthetics and Cosmetics courses. She works mainly on the following subjects: nanotechnology, cosmetology, pharmaceutical technology, aesthetics.",institutionString:"Universidade Federal de Juiz de Fora",institution:{name:"Universidade Federal de Juiz de Fora",country:{name:"Brazil"}}},{id:"219081",title:"Dr.",name:"Abdulsamed",middleName:null,surname:"Kükürt",slug:"abdulsamed-kukurt",fullName:"Abdulsamed Kükürt",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRNVJQA4/Profile_Picture_2022-03-07T13:23:04.png",biography:"Dr. Kükürt graduated from Uludağ University in Turkey. He started his academic career as a Research Assistant in the Department of Biochemistry at Kafkas University. In 2019, he completed his Ph.D. program in the Department of Biochemistry at the Institute of Health Sciences. He is currently working at the Department of Biochemistry, Kafkas University. He has 27 published research articles in academic journals, 11 book chapters, and 37 papers. He took part in 10 academic projects. He served as a reviewer for many articles. He still serves as a member of the review board in many academic journals.",institutionString:null,institution:{name:"Kafkas University",country:{name:"Turkey"}}},{id:"178366",title:"Associate Prof.",name:"Volkan",middleName:null,surname:"Gelen",slug:"volkan-gelen",fullName:"Volkan Gelen",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/178366/images/system/178366.jpg",biography:"Volkan Gelen is a Physiology specialist who received his veterinary degree from Kafkas University in 2011. Between 2011-2015, he worked as an assistant at Atatürk University, Faculty of Veterinary Medicine, Department of Physiology. In 2016, he joined Kafkas University, Faculty of Veterinary Medicine, Department of Physiology as an assistant professor. Dr. Gelen has been engaged in various academic activities at Kafkas University since 2016. There he completed 5 projects and has 3 ongoing projects. He has 60 articles published in scientific journals and 20 poster presentations in scientific congresses. His research interests include physiology, endocrine system, cancer, diabetes, cardiovascular system diseases, and isolated organ bath system studies.",institutionString:"Kafkas University",institution:{name:"Kafkas University",country:{name:"Turkey"}}},{id:"418963",title:"Dr.",name:"Augustine Ododo",middleName:"Augustine",surname:"Osagie",slug:"augustine-ododo-osagie",fullName:"Augustine Ododo Osagie",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/418963/images/16900_n.jpg",biography:"Born into the family of Osagie, a prince of the Benin Kingdom. I am currently an academic in the Department of Medical Biochemistry, University of Benin. Part of the duties are to teach undergraduate students and conduct academic research.",institutionString:null,institution:{name:"University of Benin",country:{name:"Nigeria"}}},{id:"192992",title:"Prof.",name:"Shagufta",middleName:null,surname:"Perveen",slug:"shagufta-perveen",fullName:"Shagufta Perveen",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/192992/images/system/192992.png",biography:"Prof. Shagufta Perveen is a Distinguish Professor in the Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia. Dr. Perveen has acted as the principal investigator of major research projects funded by the research unit of King Saud University. She has more than ninety original research papers in peer-reviewed journals of international repute to her credit. She is a fellow member of the Royal Society of Chemistry UK and the American Chemical Society of the United States.",institutionString:"King Saud University",institution:{name:"King Saud University",country:{name:"Saudi Arabia"}}},{id:"49848",title:"Dr.",name:"Wen-Long",middleName:null,surname:"Hu",slug:"wen-long-hu",fullName:"Wen-Long Hu",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/49848/images/system/49848.jpg",biography:"Wen-Long Hu is Chief of the Division of Acupuncture, Department of Chinese Medicine at Kaohsiung Chang Gung Memorial Hospital, as well as an adjunct associate professor at Fooyin University and Kaohsiung Medical University. Wen-Long is President of Taiwan Traditional Chinese Medicine Medical Association. He has 28 years of experience in clinical practice in laser acupuncture therapy and 34 years in acupuncture. He is an invited speaker for lectures and workshops in laser acupuncture at many symposiums held by medical associations. He owns the patent for herbal preparation and producing, and for the supercritical fluid-treated needle. Dr. Hu has published three books, 12 book chapters, and more than 30 papers in reputed journals, besides serving as an editorial board member of repute.",institutionString:"Kaohsiung Chang Gung Memorial Hospital",institution:{name:"Kaohsiung Chang Gung Memorial Hospital",country:{name:"Taiwan"}}},{id:"298472",title:"Prof.",name:"Andrey V.",middleName:null,surname:"Grechko",slug:"andrey-v.-grechko",fullName:"Andrey V. Grechko",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/298472/images/system/298472.png",biography:"Andrey Vyacheslavovich Grechko, Ph.D., Professor, is a Corresponding Member of the Russian Academy of Sciences. He graduated from the Semashko Moscow Medical Institute (Semashko National Research Institute of Public Health) with a degree in Medicine (1998), the Clinical Department of Dermatovenerology (2000), and received a second higher education in Psychology (2009). Professor A.V. Grechko held the position of Сhief Physician of the Central Clinical Hospital in Moscow. He worked as a professor at the faculty and was engaged in scientific research at the Medical University. Starting in 2013, he has been the initiator of the creation of the Federal Scientific and Clinical Center for Intensive Care and Rehabilitology, Moscow, Russian Federation, where he also serves as Director since 2015. He has many years of experience in research and teaching in various fields of medicine, is an author/co-author of more than 200 scientific publications, 13 patents, 15 medical books/chapters, including Chapter in Book «Metabolomics», IntechOpen, 2020 «Metabolomic Discovery of Microbiota Dysfunction as the Cause of Pathology».",institutionString:"Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology",institution:null},{id:"199461",title:"Prof.",name:"Natalia V.",middleName:null,surname:"Beloborodova",slug:"natalia-v.-beloborodova",fullName:"Natalia V. Beloborodova",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/199461/images/system/199461.jpg",biography:'Natalia Vladimirovna Beloborodova was educated at the Pirogov Russian National Research Medical University, with a degree in pediatrics in 1980, a Ph.D. in 1987, and a specialization in Clinical Microbiology from First Moscow State Medical University in 2004. She has been a Professor since 1996. Currently, she is the Head of the Laboratory of Metabolism, a division of the Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russian Federation. N.V. Beloborodova has many years of clinical experience in the field of intensive care and surgery. She studies infectious complications and sepsis. She initiated a series of interdisciplinary clinical and experimental studies based on the concept of integrating human metabolism and its microbiota. Her scientific achievements are widely known: she is the recipient of the Marie E. Coates Award \\"Best lecturer-scientist\\" Gustafsson Fund, Karolinska Institutes, Stockholm, Sweden, and the International Sepsis Forum Award, Pasteur Institute, Paris, France (2014), etc. Professor N.V. Beloborodova wrote 210 papers, five books, 10 chapters and has edited four books.',institutionString:"Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology",institution:null},{id:"354260",title:"Ph.D.",name:"Tércio Elyan",middleName:"Azevedo",surname:"Azevedo Martins",slug:"tercio-elyan-azevedo-martins",fullName:"Tércio Elyan Azevedo Martins",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/354260/images/16241_n.jpg",biography:"Graduated in Pharmacy from the Federal University of Ceará with the modality in Industrial Pharmacy, Specialist in Production and Control of Medicines from the University of São Paulo (USP), Master in Pharmaceuticals and Medicines from the University of São Paulo (USP) and Doctor of Science in the program of Pharmaceuticals and Medicines by the University of São Paulo. Professor at Universidade Paulista (UNIP) in the areas of chemistry, cosmetology and trichology. Assistant Coordinator of the Higher Course in Aesthetic and Cosmetic Technology at Universidade Paulista Campus Chácara Santo Antônio. Experience in the Pharmacy area, with emphasis on Pharmacotechnics, Pharmaceutical Technology, Research and Development of Cosmetics, acting mainly on topics such as cosmetology, antioxidant activity, aesthetics, photoprotection, cyclodextrin and thermal analysis.",institutionString:null,institution:{name:"University of Sao Paulo",country:{name:"Brazil"}}},{id:"334285",title:"Ph.D. Student",name:"Sameer",middleName:"Kumar",surname:"Jagirdar",slug:"sameer-jagirdar",fullName:"Sameer Jagirdar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/334285/images/14691_n.jpg",biography:"I\\'m a graduate student at the center for biosystems science and engineering at the Indian Institute of Science, Bangalore, India. I am interested in studying host-pathogen interactions at the biomaterial interface.",institutionString:null,institution:{name:"Indian Institute of Science Bangalore",country:{name:"India"}}},{id:"329795",title:"Dr.",name:"Mohd Aftab",middleName:"Aftab",surname:"Siddiqui",slug:"mohd-aftab-siddiqui",fullName:"Mohd Aftab Siddiqui",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/329795/images/15648_n.jpg",biography:"Dr. Mohd Aftab Siddiqui is currently working as Assistant Professor in the Faculty of Pharmacy, Integral University, Lucknow for the last 6 years. He has completed his Doctor in Philosophy (Pharmacology) in 2020 from Integral University, Lucknow. He completed his Bachelor in Pharmacy in 2013 and Master in Pharmacy (Pharmacology) in 2015 from Integral University, Lucknow. He is the gold medalist in Bachelor and Master degree. He qualified GPAT -2013, GPAT -2014, and GPAT 2015. His area of research is Pharmacological screening of herbal drugs/ natural products in liver and cardiac diseases. He has guided many M. Pharm. research projects. He has many national and international publications.",institutionString:"Integral University",institution:null},{id:"255360",title:"Dr.",name:"Usama",middleName:null,surname:"Ahmad",slug:"usama-ahmad",fullName:"Usama Ahmad",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/255360/images/system/255360.png",biography:"Dr. Usama Ahmad holds a specialization in Pharmaceutics from Amity University, Lucknow, India. He received his Ph.D. degree from Integral University. Currently, he’s working as an Assistant Professor of Pharmaceutics in the Faculty of Pharmacy, Integral University. From 2013 to 2014 he worked on a research project funded by SERB-DST, Government of India. He has a rich publication record with more than 32 original articles published in reputed journals, 3 edited books, 5 book chapters, and a number of scientific articles published in ‘Ingredients South Asia Magazine’ and ‘QualPharma Magazine’. He is a member of the American Association for Cancer Research, International Association for the Study of Lung Cancer, and the British Society for Nanomedicine. Dr. Ahmad’s research focus is on the development of nanoformulations to facilitate the delivery of drugs that aim to provide practical solutions to current healthcare problems.",institutionString:"Integral University",institution:{name:"Integral University",country:{name:"India"}}},{id:"30568",title:"Prof.",name:"Madhu",middleName:null,surname:"Khullar",slug:"madhu-khullar",fullName:"Madhu Khullar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/30568/images/system/30568.jpg",biography:"Dr. Madhu Khullar is a Professor of Experimental Medicine and Biotechnology at the Post Graduate Institute of Medical Education and Research, Chandigarh, India. She completed her Post Doctorate in hypertension research at the Henry Ford Hospital, Detroit, USA in 1985. She is an editor and reviewer of several international journals, and a fellow and member of several cardiovascular research societies. Dr. Khullar has a keen research interest in genetics of hypertension, and is currently studying pharmacogenetics of hypertension.",institutionString:"Post Graduate Institute of Medical Education and Research",institution:{name:"Post Graduate Institute of Medical Education and Research",country:{name:"India"}}},{id:"223233",title:"Prof.",name:"Xianquan",middleName:null,surname:"Zhan",slug:"xianquan-zhan",fullName:"Xianquan Zhan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/223233/images/system/223233.png",biography:"Xianquan Zhan received his MD and Ph.D. in Preventive Medicine at West China University of Medical Sciences. He received his post-doctoral training in oncology and cancer proteomics at the Central South University, China, and the University of Tennessee Health Science Center (UTHSC), USA. He worked at UTHSC and the Cleveland Clinic in 2001–2012 and achieved the rank of associate professor at UTHSC. Currently, he is a full professor at Central South University and Shandong First Medical University, and an advisor to MS/PhD students and postdoctoral fellows. He is also a fellow of the Royal Society of Medicine and European Association for Predictive Preventive Personalized Medicine (EPMA), a national representative of EPMA, and a member of the American Society of Clinical Oncology (ASCO) and the American Association for the Advancement of Sciences (AAAS). He is also the editor in chief of International Journal of Chronic Diseases & Therapy, an associate editor of EPMA Journal, Frontiers in Endocrinology, and BMC Medical Genomics, and a guest editor of Mass Spectrometry Reviews, Frontiers in Endocrinology, EPMA Journal, and Oxidative Medicine and Cellular Longevity. He has published more than 148 articles, 28 book chapters, 6 books, and 2 US patents in the field of clinical proteomics and biomarkers.",institutionString:"Shandong First Medical University",institution:{name:"Affiliated Hospital of Shandong Academy of Medical Sciences",country:{name:"China"}}},{id:"297507",title:"Dr.",name:"Charles",middleName:"Elias",surname:"Assmann",slug:"charles-assmann",fullName:"Charles Assmann",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/297507/images/system/297507.jpg",biography:"Charles Elias Assmann is a biologist from Federal University of Santa Maria (UFSM, Brazil), who spent some time abroad at the Ludwig-Maximilians-Universität München (LMU, Germany). He has Masters Degree in Biochemistry (UFSM), and is currently a PhD student at Biochemistry at the Department of Biochemistry and Molecular Biology of the UFSM. His areas of expertise include: Biochemistry, Molecular Biology, Enzymology, Genetics and Toxicology. He is currently working on the following subjects: Aluminium toxicity, Neuroinflammation, Oxidative stress and Purinergic system. Since 2011 he has presented more than 80 abstracts in scientific proceedings of national and international meetings. Since 2014, he has published more than 20 peer reviewed papers (including 4 reviews, 3 in Portuguese) and 2 book chapters. He has also been a reviewer of international journals and ad hoc reviewer of scientific committees from Brazilian Universities.",institutionString:"Universidade Federal de Santa Maria",institution:{name:"Universidade Federal de Santa Maria",country:{name:"Brazil"}}},{id:"217850",title:"Dr.",name:"Margarete Dulce",middleName:null,surname:"Bagatini",slug:"margarete-dulce-bagatini",fullName:"Margarete Dulce Bagatini",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/217850/images/system/217850.jpeg",biography:"Dr. Margarete Dulce Bagatini is an associate professor at the Federal University of Fronteira Sul/Brazil. She has a degree in Pharmacy and a PhD in Biological Sciences: Toxicological Biochemistry. She is a member of the UFFS Research Advisory Committee\nand a member of the Biovitta Research Institute. She is currently:\nthe leader of the research group: Biological and Clinical Studies\nin Human Pathologies, professor of postgraduate program in\nBiochemistry at UFSC and postgraduate program in Science and Food Technology at\nUFFS. She has experience in the area of pharmacy and clinical analysis, acting mainly\non the following topics: oxidative stress, the purinergic system and human pathologies, being a reviewer of several international journals and books.",institutionString:"Universidade Federal da Fronteira Sul",institution:{name:"Universidade Federal da Fronteira Sul",country:{name:"Brazil"}}},{id:"226275",title:"Ph.D.",name:"Metin",middleName:null,surname:"Budak",slug:"metin-budak",fullName:"Metin Budak",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/226275/images/system/226275.jfif",biography:"Metin Budak, MSc, PhD is an Assistant Professor at Trakya University, Faculty of Medicine. He has been Head of the Molecular Research Lab at Prof. Mirko Tos Ear and Hearing Research Center since 2018. His specializations are biophysics, epigenetics, genetics, and methylation mechanisms. He has published around 25 peer-reviewed papers, 2 book chapters, and 28 abstracts. He is a member of the Clinical Research Ethics Committee and Quantification and Consideration Committee of Medicine Faculty. His research area is the role of methylation during gene transcription, chromatin packages DNA within the cell and DNA repair, replication, recombination, and gene transcription. His research focuses on how the cell overcomes chromatin structure and methylation to allow access to the underlying DNA and enable normal cellular function.",institutionString:"Trakya University",institution:{name:"Trakya University",country:{name:"Turkey"}}},{id:"243049",title:"Dr.",name:"Anca",middleName:null,surname:"Pantea Stoian",slug:"anca-pantea-stoian",fullName:"Anca Pantea Stoian",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/243049/images/system/243049.jpg",biography:"Anca Pantea Stoian is a specialist in diabetes, nutrition, and metabolic diseases as well as health food hygiene. She also has competency in general ultrasonography.\n\nShe is an associate professor in the Diabetes, Nutrition and Metabolic Diseases Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania. She has been chief of the Hygiene Department, Faculty of Dentistry, at the same university since 2019. Her interests include micro and macrovascular complications in diabetes and new therapies. Her research activities focus on nutritional intervention in chronic pathology, as well as cardio-renal-metabolic risk assessment, and diabetes in cancer. She is currently engaged in developing new therapies and technological tools for screening, prevention, and patient education in diabetes. \n\nShe is a member of the European Association for the Study of Diabetes, Cardiometabolic Academy, CEDA, Romanian Society of Diabetes, Nutrition and Metabolic Diseases, Romanian Diabetes Federation, and Association for Renal Metabolic and Nutrition studies. She has authored or co-authored 160 papers in national and international peer-reviewed journals.",institutionString:null,institution:{name:"Carol Davila University of Medicine and Pharmacy",country:{name:"Romania"}}},{id:"279792",title:"Dr.",name:"João",middleName:null,surname:"Cotas",slug:"joao-cotas",fullName:"João Cotas",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/279792/images/system/279792.jpg",biography:"Graduate and master in Biology from the University of Coimbra.\n\nI am a research fellow at the Macroalgae Laboratory Unit, in the MARE-UC – Marine and Environmental Sciences Centre of the University of Coimbra. My principal function is the collection, extraction and purification of macroalgae compounds, chemical and bioactive characterization of the compounds and algae extracts and development of new methodologies in marine biotechnology area. \nI am associated in two projects: one consists on discovery of natural compounds for oncobiology. The other project is the about the natural compounds/products for agricultural area.\n\nPublications:\nCotas, J.; Figueirinha, A.; Pereira, L.; Batista, T. 2018. An analysis of the effects of salinity on Fucus ceranoides (Ochrophyta, Phaeophyceae), in the Mondego River (Portugal). Journal of Oceanology and Limnology. in press. DOI: 10.1007/s00343-019-8111-3",institutionString:"Faculty of Sciences and Technology of University of Coimbra",institution:null},{id:"279788",title:"Dr.",name:"Leonel",middleName:null,surname:"Pereira",slug:"leonel-pereira",fullName:"Leonel Pereira",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/279788/images/system/279788.jpg",biography:"Leonel Pereira has an undergraduate degree in Biology, a Ph.D. in Biology (specialty in Cell Biology), and a Habilitation degree in Biosciences (specialization in Biotechnology) from the Faculty of Science and Technology, University of Coimbra, Portugal, where he is currently a professor. In addition to teaching at this university, he is an integrated researcher at the Marine and Environmental Sciences Center (MARE), Portugal. His interests include marine biodiversity (algae), marine biotechnology (algae bioactive compounds), and marine ecology (environmental assessment). Since 2008, he has been the author and editor of the electronic publication MACOI – Portuguese Seaweeds Website (www.seaweeds.uc.pt). He is also a member of the editorial boards of several scientific journals. Dr. Pereira has edited or authored more than 20 books, 100 journal articles, and 45 book chapters. He has given more than 100 lectures and oral communications at various national and international scientific events. He is the coordinator of several national and international research projects. In 1998, he received the Francisco de Holanda Award (Honorable Mention) and, more recently, the Mar Rei D. Carlos award (18th edition). He is also a winner of the 2016 CHOICE Award for an outstanding academic title for his book Edible Seaweeds of the World. In 2020, Dr. Pereira received an Honorable Mention for the Impact of International Publications from the Web of Science",institutionString:"University of Coimbra",institution:{name:"University of Coimbra",country:{name:"Portugal"}}},{id:"61946",title:"Dr.",name:"Carol",middleName:null,surname:"Bernstein",slug:"carol-bernstein",fullName:"Carol Bernstein",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/61946/images/system/61946.jpg",biography:"Carol Bernstein received her PhD in Genetics from the University of California (Davis). She was a faculty member at the University of Arizona College of Medicine for 43 years, retiring in 2011. Her research interests focus on DNA damage and its underlying role in sex, aging and in the early steps of initiation and progression to cancer. In her research, she had used organisms including bacteriophage T4, Neurospora crassa, Schizosaccharomyces pombe and mice, as well as human cells and tissues. She authored or co-authored more than 140 scientific publications, including articles in major peer reviewed journals, book chapters, invited reviews and one book.",institutionString:"University of Arizona",institution:{name:"University of Arizona",country:{name:"United States of America"}}},{id:"182258",title:"Dr.",name:"Ademar",middleName:"Pereira",surname:"Serra",slug:"ademar-serra",fullName:"Ademar Serra",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/182258/images/system/182258.jpeg",biography:"Dr. Serra studied Agronomy on Universidade Federal de Mato Grosso do Sul (UFMS) (2005). He received master degree in Agronomy, Crop Science (Soil fertility and plant nutrition) (2007) by Universidade Federal da Grande Dourados (UFGD), and PhD in agronomy (Soil fertility and plant nutrition) (2011) from Universidade Federal da Grande Dourados / Escola Superior de Agricultura Luiz de Queiroz (UFGD/ESALQ-USP). Dr. Serra is currently working at Brazilian Agricultural Research Corporation (EMBRAPA). His research focus is on mineral nutrition of plants, crop science and soil science. Dr. Serra\\'s current projects are soil organic matter, soil phosphorus fractions, compositional nutrient diagnosis (CND) and isometric log ratio (ilr) transformation in compositional data analysis.",institutionString:"Brazilian Agricultural Research Corporation",institution:{name:"Brazilian Agricultural Research Corporation",country:{name:"Brazil"}}}]}},subseries:{item:{id:"10",type:"subseries",title:"Animal Physiology",keywords:"Physiology, Comparative, Evolution, Biomolecules, Organ, Homeostasis, Anatomy, Pathology, Medical, Cell Division, Cell Signaling, Cell Growth, Cell Metabolism, Endocrine, Neuroscience, Cardiovascular, Development, Aging, Development",scope:"Physiology, the scientific study of functions and mechanisms of living systems, is an essential area of research in its own right, but also in relation to medicine and health sciences. The scope of this topic will range from molecular, biochemical, cellular, and physiological processes in all animal species. Work pertaining to the whole organism, organ systems, individual organs and tissues, cells, and biomolecules will be included. Medical, animal, cell, and comparative physiology and allied fields such as anatomy, histology, and pathology with physiology links will be covered in this topic. Physiology research may be linked to development, aging, environment, regular and pathological processes, adaptation and evolution, exercise, or several other factors affecting, or involved with, animal physiology.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/10.jpg",hasOnlineFirst:!1,hasPublishedBooks:!1,annualVolume:11406,editor:{id:"202192",title:"Dr.",name:"Catrin",middleName:null,surname:"Rutland",slug:"catrin-rutland",fullName:"Catrin Rutland",profilePictureURL:"https://mts.intechopen.com/storage/users/202192/images/system/202192.png",biography:"Catrin Rutland is an Associate Professor of Anatomy and Developmental Genetics at the University of Nottingham, UK. She obtained a BSc from the University of Derby, England, a master’s degree from Technische Universität München, Germany, and a Ph.D. from the University of Nottingham. She undertook a post-doctoral research fellowship in the School of Medicine before accepting tenure in Veterinary Medicine and Science. Dr. Rutland also obtained an MMedSci (Medical Education) and a Postgraduate Certificate in Higher Education (PGCHE). She is the author of more than sixty peer-reviewed journal articles, twelve books/book chapters, and more than 100 research abstracts in cardiovascular biology and oncology. She is a board member of the European Association of Veterinary Anatomists, Fellow of the Anatomical Society, and Senior Fellow of the Higher Education Academy. Dr. Rutland has also written popular science books for the public. https://orcid.org/0000-0002-2009-4898. www.nottingham.ac.uk/vet/people/catrin.rutland",institutionString:null,institution:{name:"University of Nottingham",institutionURL:null,country:{name:"United Kingdom"}}},editorTwo:null,editorThree:null,series:{id:"10",title:"Physiology",doi:"10.5772/intechopen.72796",issn:"2631-8261"},editorialBoard:[{id:"306970",title:"Mr.",name:"Amin",middleName:null,surname:"Tamadon",slug:"amin-tamadon",fullName:"Amin Tamadon",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002oHR5wQAG/Profile_Picture_1623910304139",institutionString:null,institution:{name:"Bushehr University of Medical Sciences",institutionURL:null,country:{name:"Iran"}}},{id:"251314",title:"Dr.",name:"Juan Carlos",middleName:null,surname:"Gardón",slug:"juan-carlos-gardon",fullName:"Juan Carlos Gardón",profilePictureURL:"https://mts.intechopen.com/storage/users/251314/images/system/251314.jpeg",institutionString:"Catholic University of Valencia San Vicente Mártir, Spain",institution:null},{id:"245306",title:"Dr.",name:"María Luz",middleName:null,surname:"Garcia Pardo",slug:"maria-luz-garcia-pardo",fullName:"María Luz Garcia Pardo",profilePictureURL:"https://mts.intechopen.com/storage/users/245306/images/system/245306.png",institutionString:null,institution:{name:"Miguel Hernandez University",institutionURL:null,country:{name:"Spain"}}},{id:"283315",title:"Prof.",name:"Samir",middleName:null,surname:"El-Gendy",slug:"samir-el-gendy",fullName:"Samir El-Gendy",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRduYQAS/Profile_Picture_1606215849748",institutionString:null,institution:{name:"Alexandria University",institutionURL:null,country:{name:"Egypt"}}}]},onlineFirstChapters:{},publishedBooks:{paginationCount:3,paginationItems:[{type:"book",id:"8545",title:"Animal Reproduction in Veterinary Medicine",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/8545.jpg",slug:"animal-reproduction-in-veterinary-medicine",publishedDate:"January 20th 2021",editedByType:"Edited by",bookSignature:"Faruk Aral, Rita Payan-Carreira and Miguel Quaresma",hash:"13aaddf5fdbbc78387e77a7da2388bf6",volumeInSeries:6,fullTitle:"Animal Reproduction in Veterinary Medicine",editors:[{id:"25600",title:"Prof.",name:"Faruk",middleName:null,surname:"Aral",slug:"faruk-aral",fullName:"Faruk Aral",profilePictureURL:"https://mts.intechopen.com/storage/users/25600/images/system/25600.jpg",institutionString:"Independent Researcher",institution:{name:"Harran University",institutionURL:null,country:{name:"Turkey"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"8460",title:"Reproductive Biology and Technology in Animals",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/8460.jpg",slug:"reproductive-biology-and-technology-in-animals",publishedDate:"April 15th 2020",editedByType:"Edited by",bookSignature:"Juan Carlos Gardón Poggi and Katy Satué Ambrojo",hash:"32ef5fe73998dd723d308225d756fa1e",volumeInSeries:4,fullTitle:"Reproductive Biology and Technology in Animals",editors:[{id:"251314",title:"Dr.",name:"Juan Carlos",middleName:null,surname:"Gardón",slug:"juan-carlos-gardon",fullName:"Juan Carlos Gardón",profilePictureURL:"https://mts.intechopen.com/storage/users/251314/images/system/251314.jpeg",institutionString:"Catholic University of Valencia San Vicente Mártir, Spain",institution:null}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"7233",title:"New Insights into Theriogenology",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7233.jpg",slug:"new-insights-into-theriogenology",publishedDate:"December 5th 2018",editedByType:"Edited by",bookSignature:"Rita Payan-Carreira",hash:"74f4147e3fb214dd050e5edd3aaf53bc",volumeInSeries:1,fullTitle:"New Insights into Theriogenology",editors:[{id:"38652",title:"Prof.",name:"Rita",middleName:null,surname:"Payan-Carreira",slug:"rita-payan-carreira",fullName:"Rita Payan-Carreira",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRiFPQA0/Profile_Picture_1614601496313",institutionString:null,institution:{name:"University of Évora",institutionURL:null,country:{name:"Portugal"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null}]},testimonialsList:[{id:"8",text:"I work with IntechOpen for a number of reasons: their professionalism, their mission in support of Open Access publishing, and the quality of their peer-reviewed publications, but also because they believe in equality.",author:{id:"202192",name:"Catrin",surname:"Rutland",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/202192/images/system/202192.png",slug:"catrin-rutland",institution:{id:"134",name:"University of Nottingham",country:{id:null,name:"United Kingdom"}}}},{id:"27",text:"The opportunity to work with a prestigious publisher allows for the possibility to collaborate with more research groups interested in animal nutrition, leading to the development of new feeding strategies and food valuation while being more sustainable with the environment, allowing more readers to learn about the subject.",author:{id:"175967",name:"Manuel",surname:"Gonzalez Ronquillo",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/175967/images/system/175967.png",slug:"manuel-gonzalez-ronquillo",institution:{id:"6221",name:"Universidad Autónoma del Estado de México",country:{id:null,name:"Mexico"}}}},{id:"18",text:"It was great publishing with IntechOpen, the process was straightforward and I had support all along.",author:{id:"71579",name:"Berend",surname:"Olivier",institutionString:"Utrecht University",profilePictureURL:"https://mts.intechopen.com/storage/users/71579/images/system/71579.png",slug:"berend-olivier",institution:{id:"253",name:"Utrecht University",country:{id:null,name:"Netherlands"}}}}]},submityourwork:{pteSeriesList:[],lsSeriesList:[],hsSeriesList:[],sshSeriesList:[],subseriesList:[],annualVolumeBook:{},thematicCollection:[],selectedSeries:null,selectedSubseries:null},seriesLanding:{item:null},libraryRecommendation:{success:null,errors:{},institutions:[]},route:{name:"chapter.detail",path:"/chapters/74141",hash:"",query:{},params:{id:"74141"},fullPath:"/chapters/74141",meta:{},from:{name:null,path:"/",hash:"",query:{},params:{},fullPath:"/",meta:{}}}},function(){var e;(e=document.currentScript||document.scripts[document.scripts.length-1]).parentNode.removeChild(e)}()