Social skills emphasized in the preschool classroom.
\\n\\n
IntechOpen was founded by scientists, for scientists, in order to make book publishing accessible around the globe. Over the last two decades, this has driven Open Access (OA) book publishing whilst levelling the playing field for global academics. Through our innovative publishing model and the support of the research community, we have now published over 5,700 Open Access books and are visited online by over three million academics every month. These researchers are increasingly working in broad technology-based subjects, driving multidisciplinary academic endeavours into human health, environment, and technology.
\\n\\nBy listening to our community, and in order to serve these rapidly growing areas which lie at the core of IntechOpen's expertise, we are launching a portfolio of Open Science journals:
\\n\\nAll three journals will publish under an Open Access model and embrace Open Science policies to help support the changing needs of academics in these fast-moving research areas. There will be direct links to preprint servers and data repositories, allowing full reproducibility and rapid dissemination of published papers to help accelerate the pace of research. Each journal has renowned Editors in Chief who will work alongside a global Editorial Board, delivering robust single-blind peer review. Supported by our internal editorial teams, this will ensure our authors will receive a quick, user-friendly, and personalised publishing experience.
\\n\\n"By launching our journals portfolio we are introducing new, dedicated homes for interdisciplinary technology-focused researchers to publish their work, whilst embracing Open Science and creating a unique global home for academics to disseminate their work. We are taking a leap toward Open Science continuing and expanding our fundamental commitment to openly sharing scientific research across the world, making it available for the benefit of all." Dr. Sara Uhac, IntechOpen CEO
\\n\\n"Our aim is to promote and create better science for a better world by increasing access to information and the latest scientific developments to all scientists, innovators, entrepreneurs and students and give them the opportunity to learn, observe and contribute to knowledge creation. Open Science promotes a swifter path from research to innovation to produce new products and services." Alex Lazinica, IntechOpen founder
\\n\\nIn conclusion, Natalia Reinic Babic, Head of Journal Publishing and Open Science at IntechOpen adds:
\\n\\n“On behalf of the journal team I’d like to thank all our Editors in Chief, Editorial Boards, internal supporting teams, and our scientific community for their continuous support in making this portfolio a reality - we couldn’t have done it without you! With your support in place, we are confident these journals will become as impactful and successful as our book publishing program and bring us closer to a more open (science) future.”
\\n\\nWe invite you to visit the journals homepage and learn more about the journal’s Editorial Boards, scope and vision as all three journals are now open for submissions.
\\n\\nFeel free to share this news on social media and help us mark this memorable moment!
\\n\\n\\n"}]',published:!0,mainMedia:{caption:"",originalUrl:"/media/original/237"}},components:[{type:"htmlEditorComponent",content:'
After years of being acknowledged as the world's leading publisher of Open Access books, today, we are proud to announce we’ve successfully launched a portfolio of Open Science journals covering rapidly expanding areas of interdisciplinary research.
\n\n\n\nIntechOpen was founded by scientists, for scientists, in order to make book publishing accessible around the globe. Over the last two decades, this has driven Open Access (OA) book publishing whilst levelling the playing field for global academics. Through our innovative publishing model and the support of the research community, we have now published over 5,700 Open Access books and are visited online by over three million academics every month. These researchers are increasingly working in broad technology-based subjects, driving multidisciplinary academic endeavours into human health, environment, and technology.
\n\nBy listening to our community, and in order to serve these rapidly growing areas which lie at the core of IntechOpen's expertise, we are launching a portfolio of Open Science journals:
\n\nAll three journals will publish under an Open Access model and embrace Open Science policies to help support the changing needs of academics in these fast-moving research areas. There will be direct links to preprint servers and data repositories, allowing full reproducibility and rapid dissemination of published papers to help accelerate the pace of research. Each journal has renowned Editors in Chief who will work alongside a global Editorial Board, delivering robust single-blind peer review. Supported by our internal editorial teams, this will ensure our authors will receive a quick, user-friendly, and personalised publishing experience.
\n\n"By launching our journals portfolio we are introducing new, dedicated homes for interdisciplinary technology-focused researchers to publish their work, whilst embracing Open Science and creating a unique global home for academics to disseminate their work. We are taking a leap toward Open Science continuing and expanding our fundamental commitment to openly sharing scientific research across the world, making it available for the benefit of all." Dr. Sara Uhac, IntechOpen CEO
\n\n"Our aim is to promote and create better science for a better world by increasing access to information and the latest scientific developments to all scientists, innovators, entrepreneurs and students and give them the opportunity to learn, observe and contribute to knowledge creation. Open Science promotes a swifter path from research to innovation to produce new products and services." Alex Lazinica, IntechOpen founder
\n\nIn conclusion, Natalia Reinic Babic, Head of Journal Publishing and Open Science at IntechOpen adds:
\n\n“On behalf of the journal team I’d like to thank all our Editors in Chief, Editorial Boards, internal supporting teams, and our scientific community for their continuous support in making this portfolio a reality - we couldn’t have done it without you! With your support in place, we are confident these journals will become as impactful and successful as our book publishing program and bring us closer to a more open (science) future.”
\n\nWe invite you to visit the journals homepage and learn more about the journal’s Editorial Boards, scope and vision as all three journals are now open for submissions.
\n\nFeel free to share this news on social media and help us mark this memorable moment!
\n\n\n'}],latestNews:[{slug:"intechopen-supports-asapbio-s-new-initiative-publish-your-reviews-20220729",title:"IntechOpen Supports ASAPbio’s New Initiative Publish Your Reviews"},{slug:"webinar-introduction-to-open-science-wednesday-18-may-1-pm-cest-20220518",title:"Webinar: Introduction to Open Science | Wednesday 18 May, 1 PM CEST"},{slug:"step-in-the-right-direction-intechopen-launches-a-portfolio-of-open-science-journals-20220414",title:"Step in the Right Direction: IntechOpen Launches a Portfolio of Open Science Journals"},{slug:"let-s-meet-at-london-book-fair-5-7-april-2022-olympia-london-20220321",title:"Let’s meet at London Book Fair, 5-7 April 2022, Olympia London"},{slug:"50-books-published-as-part-of-intechopen-and-knowledge-unlatched-ku-collaboration-20220316",title:"50 Books published as part of IntechOpen and Knowledge Unlatched (KU) Collaboration"},{slug:"intechopen-joins-the-united-nations-sustainable-development-goals-publishers-compact-20221702",title:"IntechOpen joins the United Nations Sustainable Development Goals Publishers Compact"},{slug:"intechopen-signs-exclusive-representation-agreement-with-lsr-libros-servicios-y-representaciones-s-a-de-c-v-20211123",title:"IntechOpen Signs Exclusive Representation Agreement with LSR Libros Servicios y Representaciones S.A. de C.V"},{slug:"intechopen-expands-partnership-with-research4life-20211110",title:"IntechOpen Expands Partnership with Research4Life"}]},book:{item:{type:"book",id:"6584",leadTitle:null,fullTitle:"Probabilistic Modeling in System Engineering",title:"Probabilistic Modeling in System Engineering",subtitle:null,reviewType:"peer-reviewed",abstract:'This book is intended for systems analysts, designers, developers, users, experts, as well as those involved in quality, risk, safety and security management, and, of course, scientists and students. The various sets of original and traditional probabilistic models and interesting results of their applications to the research of different systems are presented. The models are understandable and applicable for solving system engineering problems: to optimize system requirements, compare different processes, rationale technical decisions, carry out tests, adjust technological parameters, and predict and analyze quality and risks. The engineering decisions, scientifically proven by the proposed models and software tools, can provide purposeful, essential improvement of quality and mitigation of risks, and reduce the expense of operating systems. Models, methods, and software tools can also be used in education for system analysis and mathematical modeling on specializations, for example "systems engineering," "operations research," "enterprise management," "project management," "risk management," "quality of systems," "safety and security," "smart systems," "system of systems," etc.',isbn:"978-1-78984-409-2",printIsbn:"978-1-78923-774-0",pdfIsbn:"978-1-83881-570-7",doi:"10.5772/intechopen.71396",price:119,priceEur:129,priceUsd:155,slug:"probabilistic-modeling-in-system-engineering",numberOfPages:290,isOpenForSubmission:!1,isInWos:null,isInBkci:!1,hash:"9b2dfbad4b959562bf4f4239f6b34cba",bookSignature:"Andrey Kostogryzov",publishedDate:"September 26th 2018",coverURL:"https://cdn.intechopen.com/books/images_new/6584.jpg",numberOfDownloads:11789,numberOfWosCitations:9,numberOfCrossrefCitations:23,numberOfCrossrefCitationsByBook:8,numberOfDimensionsCitations:33,numberOfDimensionsCitationsByBook:13,hasAltmetrics:0,numberOfTotalCitations:65,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"October 11th 2017",dateEndSecondStepPublish:"November 1st 2017",dateEndThirdStepPublish:"January 5th 2018",dateEndFourthStepPublish:"March 21st 2018",dateEndFifthStepPublish:"May 20th 2018",currentStepOfPublishingProcess:5,indexedIn:"1,2,3,4,5,6,7",editedByType:"Edited by",kuFlag:!1,featuredMarkup:null,editors:[{id:"148322",title:"Dr.",name:"Andrey",middleName:null,surname:"Kostogryzov",slug:"andrey-kostogryzov",fullName:"Andrey Kostogryzov",profilePictureURL:"https://mts.intechopen.com/storage/users/148322/images/system/148322.jpeg",biography:"Andrey Kostogryzov (1957.05.16) – Chief Researcher of the Federal Research Center 'Computer Science and Control” of the Russian Academy of Sciences (Moscow, Russia), Director and Scientific Leader of the Research Institute of Applied Mathematics and Certification. \nHonored Science Worker of the Russian Federation, Dr. of Engineering Science, Professor, Corresponding Member of the Russian Academy of Rockets and Artillery Sciences. The Winner of the Award of the Government of the Russian Federation in the Field of Science and Engineering. \nDeputy Chairman of the Committee \"Business Sequrity \" and Chairman of SC 'Information Technologies” of the Committee \"Industrial Safety” of the Chamber of Commerce and Industry of the Russian Federation. \nDeputy Chairman of the National TC 'Information Technologies”, Chairman of SC 'System and Software Engineering”. \nThe mamber of the Commission on Technogenic Safety of the Russian Academy of Sciences. \nCertified Expert of the Russian Academy of Sciences, the Ministry of Education of the Russian Federation, PJSC Gazprom. \nThe author of more than 100 mathematical models for analyzing and optimizing quality and risks and more than 210 scientific works, including 20 books",institutionString:"Russian Academy of Sciences",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"2",totalChapterViews:"0",totalEditedBooks:"2",institution:{name:"Russian Academy of Sciences",institutionURL:null,country:{name:"Russia"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,coeditorOne:null,coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"123",title:"System Engineering",slug:"system-engineering"}],chapters:[{id:"60336",title:"Probabilistic Modelling in Solving Analytical Problems of System Engineering",doi:"10.5772/intechopen.75686",slug:"probabilistic-modelling-in-solving-analytical-problems-of-system-engineering",totalDownloads:1025,totalCrossrefCites:1,totalDimensionsCites:1,hasAltmetrics:0,abstract:"This chapter provides some aspects to probabilistic modelling in solving analytical problems of system engineering. The historically developed system of the formation of scientific bases of engineering calculations of characteristics of strength, stability, durability, reliability, survivability and safety is considered. The features of deterministic and probabilistic problems of evaluation of the characteristics of strength, stiffness, steadiness, durability and survivability are considered. Probabilistic problems of reliability, security, safety and risk assessment of engineering systems are formulated. Theoretical bases and methods of probabilistic modelling of engineering systems are stated. The main directions of solving the problems of ensuring security and safety according to the accident risk criteria are determined. The possibilities of probabilistic modelling methods in solving the problems of strength, reliability and safety of engineering systems are shown in practical examples.",signatures:"Anatoly Lepikhin, Vladimir Moskvichev and Nikolay Machutov",downloadPdfUrl:"/chapter/pdf-download/60336",previewPdfUrl:"/chapter/pdf-preview/60336",authors:[{id:"231405",title:"Prof.",name:"Anatoly",surname:"Lepikhin",slug:"anatoly-lepikhin",fullName:"Anatoly Lepikhin"},{id:"231465",title:"Prof.",name:"Vladimir",surname:"Moskvichev",slug:"vladimir-moskvichev",fullName:"Vladimir Moskvichev"},{id:"231470",title:"Prof.",name:"Nikolay",surname:"Machytov",slug:"nikolay-machytov",fullName:"Nikolay Machytov"}],corrections:null},{id:"61228",title:"Probabilistic Methods and Technologies of Risk Prediction and Rationale of Preventive Measures by Using “Smart Systems”: Applications to Coal Branch for Increasing Industrial Safety of Enterprises",doi:"10.5772/intechopen.75109",slug:"probabilistic-methods-and-technologies-of-risk-prediction-and-rationale-of-preventive-measures-by-us",totalDownloads:976,totalCrossrefCites:3,totalDimensionsCites:3,hasAltmetrics:0,abstract:"Abilities of “smart systems” for processing information, adaptation to conditions of uncertainty, and performance of scientifically proven preventive actions in real time are analyzed. Basic probabilistic models and technologies for the analysis of complex systems, using “smart systems,” ways of generation of probabilistic models for prognostic researches of the new systems projected, modernized, or transformed, are proposed. The proposed methods are described to predict risks to lose integrity for complex structures on the given prognostic time and rationale of preventive measures considering admissible risk, estimate “smart system” operation quality, and predict in real time the mean residual time before the next parameter abnormalities. The methods and technologies are implemented on the level of the remote monitoring systems. The application is illustrated on the examples of the joint-stock company “Siberian Coal Energy Company.”",signatures:"Vladimir Artemyev, Jury Rudenko and George Nistratov",downloadPdfUrl:"/chapter/pdf-download/61228",previewPdfUrl:"/chapter/pdf-preview/61228",authors:[{id:"156749",title:"Dr.",name:"George",surname:"Nistratov",slug:"george-nistratov",fullName:"George Nistratov"},{id:"240686",title:"Dr.",name:"Rudenko",surname:"Jury",slug:"rudenko-jury",fullName:"Rudenko Jury"},{id:"240687",title:"Dr.",name:"Vladimir",surname:"Artemyev",slug:"vladimir-artemyev",fullName:"Vladimir Artemyev"}],corrections:null},{id:"61439",title:"Probabilistic Modeling Processes for Oil and Gas",doi:"10.5772/intechopen.74963",slug:"probabilistic-modeling-processes-for-oil-and-gas",totalDownloads:1145,totalCrossrefCites:2,totalDimensionsCites:5,hasAltmetrics:0,abstract:"Different uncertainties are researched for providing safe and effective development of hydrocarbon deposits and rational operation of oil and gas systems (OGS). The original models and methods, applicable in education and practice for solving problems of system engineering, are proposed. These models allow us to analyze natural and technogenic threats for oil and gas systems on a probabilistic level for a given prognostic time. Transformation and adaptation of models are demonstrated by examples connected with non-destructive testing. The measures of counteraction to threats for the typical manufacturing processes of gas preparation equipment on enterprise are analyzed. The risks for pipelines, pumping liquefied natural gas across the South American territory, are predicted. Results of probabilistic modeling of the sea gas and oil-producing systems from their vulnerability point of view (including various scenarios of possible terrorist influences) are analyzed and interpreted.",signatures:"Vsevolod Kershenbaum, Leonid Grigoriev, Petr Kanygin and Andrey\nNistratov",downloadPdfUrl:"/chapter/pdf-download/61439",previewPdfUrl:"/chapter/pdf-preview/61439",authors:[{id:"156748",title:"Dr.",name:"Andrey",surname:"Nistratov",slug:"andrey-nistratov",fullName:"Andrey Nistratov"},{id:"230578",title:"Prof.",name:"Leonid",surname:"Grigoriev",slug:"leonid-grigoriev",fullName:"Leonid Grigoriev"},{id:"230582",title:"Prof.",name:"Vsevolod",surname:"Kershenbaum",slug:"vsevolod-kershenbaum",fullName:"Vsevolod Kershenbaum"},{id:"240730",title:"Dr.",name:"Petr",surname:"Kanygin",slug:"petr-kanygin",fullName:"Petr Kanygin"}],corrections:null},{id:"60253",title:"Probabilistic Analysis of Transportation Systems for Oil and Natural Gas",doi:"10.5772/intechopen.75078",slug:"probabilistic-analysis-of-transportation-systems-for-oil-and-natural-gas",totalDownloads:986,totalCrossrefCites:3,totalDimensionsCites:3,hasAltmetrics:0,abstract:"In this chapter, the need of probabilistic modeling for design, construction, and operation of oil and gas pipelines is justified. Such modeling should use information and databases on deterministic and statistical dependencies related to deformation, damage accumulation, failure, fracture accidents, and catastrophes. The probabilistic design equations and their parameters for the characteristics of strength, durability, fracture toughness, risks of accidents, and manmade catastrophes are given. The economic efficiency of pipeline management based on controlling probabilistic characteristics through conducting diagnostic, repair-and-renewal operations while ensuring the acceptable levels of reliability and safety parameters is substantiated. The results of studies in the field of statistics and probabilities of emergency situations during manufacturing, construction, and operation conducted by Russian and foreign specialists are presented.",signatures:"Yuriy V. Lisin, Nikolay A. Makhutov, Vladimir A. Nadein and Dmitriy\nA. Neganov",downloadPdfUrl:"/chapter/pdf-download/60253",previewPdfUrl:"/chapter/pdf-preview/60253",authors:[{id:"231592",title:"Mr.",name:"Vladimir",surname:"Nadein",slug:"vladimir-nadein",fullName:"Vladimir Nadein"},{id:"256060",title:"Dr.",name:"Nikolay A.",surname:"Makhutov",slug:"nikolay-a.-makhutov",fullName:"Nikolay A. Makhutov"},{id:"256061",title:null,name:"Dmitriy A.",surname:"Neganov",slug:"dmitriy-a.-neganov",fullName:"Dmitriy A. Neganov"},{id:"256456",title:"Dr.",name:"Yuriy V.",surname:"Lisin",slug:"yuriy-v.-lisin",fullName:"Yuriy V. Lisin"}],corrections:null},{id:"61846",title:"Decision-Making Model for Offshore Offloading Operations Based on Probabilistic Risk Assessment",doi:"10.5772/intechopen.75833",slug:"decision-making-model-for-offshore-offloading-operations-based-on-probabilistic-risk-assessment",totalDownloads:940,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"To explore offshore oil fields in deepwater, the use of a floating production storage and offloading (FPSO) unit coupled to a shuttle tanker is economically and technically feasible. Shuttle tankers like system for oil transportation are increasingly being accepted as a preferred transportation method for remote and deepwater offshore developments. The offloading operation is considered one of the riskiest operations in offshore environment. The chapter presents a risk-based analysis method aiming at defining the risk profile associated with an offloading operation. For offloading operations, the risk profile is usually evaluated considering that the offloading operation has an approximate duration of 24 hours. The method follows three basic steps: identification of hazard, definition of failure scenarios and their probability of occurrence, and evaluation of failure consequences. The decision-making theory is used to evaluate the possibility of emergency disconnection during the operation. The method is applied to evaluate the risk profile of an offloading operation in Campos Basin, Brazil, considering a FPSO moored with Differentiated Complacent Anchoring System (DICAS). The method is used to model the risk scenario associated with shuttle tanker main engine failure as initiating event. The changes in environmental conditions have great influence in risk profile and increase the probability of disconnection.",signatures:"C. E. Patiño Rodriguez",downloadPdfUrl:"/chapter/pdf-download/61846",previewPdfUrl:"/chapter/pdf-preview/61846",authors:[{id:"232268",title:"Ph.D.",name:"Carmen",surname:"Patino-Rodriguez",slug:"carmen-patino-rodriguez",fullName:"Carmen Patino-Rodriguez"}],corrections:null},{id:"61058",title:"Natural Hazards: Systematic Assessment of Their Contribution to Risk and Their Consequences",doi:"10.5772/intechopen.76503",slug:"natural-hazards-systematic-assessment-of-their-contribution-to-risk-and-their-consequences",totalDownloads:860,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"The significance of event scenarios from a variety of natural hazards —from seismotectonic over meteorological, hydrological up to biological ones — to all types of industrial facilitieshas been recognized in the near past and needs to be addressed systematically in the safety assessment. The most recent approaches for assessing the risk contribution from these hazards and their consequences start with a site-specific qualitative as well as quantitative screening of those individual hazards and event combinations with such hazards, which can be directly related, correlated, or occur independently during the mission time of another. In the second step, for those hazards and hazard combinations remaining with a non-negligible occurrence frequency, a detailed analysis of the facility-specific event scenario including interdependencies between the hazards to be considered, and the safety features and countermeasures in the facility being investigated is conducted in order to estimate the corresponding risk contribution and consequences.",signatures:"Berg Heinz-Peter and Roewekamp Marina",downloadPdfUrl:"/chapter/pdf-download/61058",previewPdfUrl:"/chapter/pdf-preview/61058",authors:[{id:"11381",title:"Dr.",name:"Marina",surname:"Röwekamp",slug:"marina-rowekamp",fullName:"Marina Röwekamp"},{id:"231793",title:"D.Sc.",name:"Heinz Peter",surname:"Berg",slug:"heinz-peter-berg",fullName:"Heinz Peter Berg"}],corrections:null},{id:"60800",title:"Models for Testing Modifiable Systems",doi:"10.5772/intechopen.75126",slug:"models-for-testing-modifiable-systems",totalDownloads:946,totalCrossrefCites:0,totalDimensionsCites:1,hasAltmetrics:0,abstract:"The work describes reliability and security growth models for modifiable software systems as a result of revisions and tests performed for specified input data areas. The work shows that the known reliability growth models are of monotonically increasing type, which is not in line with current multi-version team technologies of software development that are primarily based on the open-source code. The authors suggest new non-monotonically increasing models of software reliability evaluation and planning that allow taking into account the effect of decreased reliability resulting from updates or wavefront errors. The work describes the elaborated bigeminal and generic reliability evaluation model as well as the models and test planning procedures. The work includes calculated expressions for the evaluation of the model accuracy and shows that the developed models are adequate to real data. An example is given of transition from probability models to fuzzy models in case of incomplete basic data. The work provides general recommendations for selection of software tool testing models.",signatures:"Alexey Markov, Alexander Barabanov and Valentin Tsirlov",downloadPdfUrl:"/chapter/pdf-download/60800",previewPdfUrl:"/chapter/pdf-preview/60800",authors:[{id:"231225",title:"Prof.",name:"Alexey",surname:"Markov",slug:"alexey-markov",fullName:"Alexey Markov"},{id:"240610",title:"Dr.",name:"Alexander",surname:"Barabanov",slug:"alexander-barabanov",fullName:"Alexander Barabanov"},{id:"240611",title:"Dr.",name:"Valrntin",surname:"Tsirov",slug:"valrntin-tsirov",fullName:"Valrntin Tsirov"}],corrections:null},{id:"62864",title:"Probabilistic Model of Delay Propagation along the Train Flow",doi:"10.5772/intechopen.75494",slug:"probabilistic-model-of-delay-propagation-along-the-train-flow",totalDownloads:898,totalCrossrefCites:3,totalDimensionsCites:4,hasAltmetrics:0,abstract:"In this chapter, we propose a probabilistic model for train delay propagation. There are deduced formulas for the probability distributions of arrival headways and knock-on delays depending on distributions of the primary delay duration and the departure headways. We prove some key mathematical statements. The obtained formulas allow to predict the frequency of train arrival delays and to determine the optimal traffic adjustments. Several important special cases of initial probability distributions are considered. Results of the theoretical analysis are verified by comparison with statistical data on the train traffic at the Russian railways.",signatures:"Vladimir Chebotarev, Boris Davydov and Kseniya Kablukova",downloadPdfUrl:"/chapter/pdf-download/62864",previewPdfUrl:"/chapter/pdf-preview/62864",authors:[{id:"231571",title:"Ms.",name:"Kseniya",surname:"Kablukova",slug:"kseniya-kablukova",fullName:"Kseniya Kablukova"},{id:"240782",title:"Prof.",name:"Vladimir",surname:"Chebotarev",slug:"vladimir-chebotarev",fullName:"Vladimir Chebotarev"},{id:"240784",title:"Dr.",name:"Boris",surname:"Davydov",slug:"boris-davydov",fullName:"Boris Davydov"}],corrections:null},{id:"59821",title:"The Approach of Probabilistic Risk Analysis and Rationale of Preventive Measures for Space Systems and Technologies",doi:"10.5772/intechopen.74212",slug:"the-approach-of-probabilistic-risk-analysis-and-rationale-of-preventive-measures-for-space-systems-a",totalDownloads:826,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"This chapter is devoted to the probabilistic risk analysis of collision of satellites with space debris. The uncertainty and random space-time characteristics of dynamic space objects are researched for the rationale of preventive measures for space systems and technologies. The proposed approach is illustrated by analyzing space debris and their distribution on satellite orbits. The actuality is confirmed by many dangerous convergences of controlled satellites and fragments of the old objects that have been discarded and transformed into uncontrolled debris. The research demonstrates a possibility of probabilistic modeling allows calculating preventive measures for avoiding collisions.",signatures:"Nikolay Paramonov",downloadPdfUrl:"/chapter/pdf-download/59821",previewPdfUrl:"/chapter/pdf-preview/59821",authors:[{id:"226716",title:"Dr.",name:"Nikolay",surname:"Paramonov",slug:"nikolay-paramonov",fullName:"Nikolay Paramonov"}],corrections:null},{id:"60048",title:"Periodic Monitoring and Recovery of Resources in Information Systems",doi:"10.5772/intechopen.75232",slug:"periodic-monitoring-and-recovery-of-resources-in-information-systems",totalDownloads:887,totalCrossrefCites:1,totalDimensionsCites:3,hasAltmetrics:0,abstract:"This section deals with the issues of business continuity and recovery after disasters. The authors analyzed standards, laws, and regulations pertaining to the parameters of periodic monitoring and recovery in information systems. This section includes mathematical models of resources and environment periodic monitoring as well as periodic backup and recovery after interruptions or disasters. The work demonstrates that the well-known deterministic periodic monitoring and backup models do not take into account stochastic peculiarities of ergatic systems to the full extent. The authors developed new stochastic models of restricted monitoring and backup that allow taking into consideration resources constrains and random factors of information systems operation. The notion of Bernoulli stream has been introduced. This section suggests the criteria for selecting deterministic or stochastic monitoring and backup models and their combinations. A solution of direct and reverse task of the calculation of control and monitoring procedures frequency is offered. This section also provides a methodology for information system stability management, considering periodic monitoring, rollback, and recovery in case of interruption.",signatures:"Alexey Markov, Alexander Barabanov and Valentin Tsirlov",downloadPdfUrl:"/chapter/pdf-download/60048",previewPdfUrl:"/chapter/pdf-preview/60048",authors:[{id:"231225",title:"Prof.",name:"Alexey",surname:"Markov",slug:"alexey-markov",fullName:"Alexey Markov"},{id:"240610",title:"Dr.",name:"Alexander",surname:"Barabanov",slug:"alexander-barabanov",fullName:"Alexander Barabanov"},{id:"249499",title:"Dr.",name:"Valentin",surname:"Tsirlov",slug:"valentin-tsirlov",fullName:"Valentin Tsirlov"}],corrections:null},{id:"59963",title:"Probabilistic Analysis of the Influence of Staff Qualification and Information-Psychological Conditions on the Level of Systems Information Security",doi:"10.5772/intechopen.75079",slug:"probabilistic-analysis-of-the-influence-of-staff-qualification-and-information-psychological-conditi",totalDownloads:776,totalCrossrefCites:7,totalDimensionsCites:8,hasAltmetrics:0,abstract:"Taking into account the criticality of the “human factor,” the probabilistic approach for analysis is proposed, including: a model for predicting and assessing the level of systems information security, considering random events, including dependent events; model of information-psychological impact on staff; methodical approach for analyzing an influence of staff qualifications and psychological conditions on the level of system information security. The effectiveness of the application is demonstrated by examples.",signatures:"Igor Goncharov, Nikita Goncharov, Pavel Parinov, Sergey\nKochedykov and Alexander Dushkin",downloadPdfUrl:"/chapter/pdf-download/59963",previewPdfUrl:"/chapter/pdf-preview/59963",authors:[{id:"231528",title:"Ph.D.",name:"Igor",surname:"Goncharov",slug:"igor-goncharov",fullName:"Igor Goncharov"},{id:"240727",title:"Mr.",name:"Nikita",surname:"Goncharov",slug:"nikita-goncharov",fullName:"Nikita Goncharov"},{id:"240728",title:"Mr.",name:"Pavel",surname:"Parinov",slug:"pavel-parinov",fullName:"Pavel Parinov"},{id:"240729",title:"Mr.",name:"Sergey",surname:"Kochedykov",slug:"sergey-kochedykov",fullName:"Sergey Kochedykov"},{id:"249097",title:"Dr.",name:"Alexander",surname:"Dushkin",slug:"alexander-dushkin",fullName:"Alexander Dushkin"}],corrections:null},{id:"60856",title:"Analysis of Terrorist Attack Scenarios and Measures for Countering Terrorist Threats",doi:"10.5772/intechopen.75099",slug:"analysis-of-terrorist-attack-scenarios-and-measures-for-countering-terrorist-threats",totalDownloads:1525,totalCrossrefCites:3,totalDimensionsCites:5,hasAltmetrics:0,abstract:"The chapter will present the classification of the types of modern terrorism and describe scenarios and probabilistic models of ordinary, technological, and the so-called intelligent terrorism that are distinguished by their triggering events, propagation modes, damaging factors, probabilities, and consequences. 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This requires extensive analysis of developing trends in scientific research in order to offer our readers relevant content. Creating the book catalogue is also based on keeping track of the most read, downloaded and highly cited chapters and books and relaunching similar topics. I am also responsible for consulting with our Scientific Advisors on which book topics to add to our catalogue and sending possible book proposal topics to them for evaluation. Once the catalogue is complete, I contact leading researchers in their respective fields and ask them to become possible Academic Editors for each book project. Once an editor is appointed, I prepare all necessary information required for them to begin their work, as well as guide them through the editorship process. I also assist editors in inviting suitable authors to contribute to a specific book project and each year, I identify and invite exceptional editors to join IntechOpen as Scientific Advisors. 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Social competence is a term covering a variety of diverse internal factors and external behaviors that influence the likelihood and quality of social interaction.
In this chapter, the role of the early childhood educator in positively influencing the social competence of preschool children is explored. Specifically, the considerations, practices, and evidence bases for social competence teaching strategies and interventions in inclusive environments are emphasized. First, social competence is defined, and its importance to early childhood development is explored. Then, the impact of disabilities on social skills is touched upon. Universal considerations for preschool educators are presented, highlighting parallels between best early childhood education practices and those which form a foundation for proactively addressing social competence. Next, specific strategies and interventions to address social skills are shared. The chapter concludes with a model integrating these practices into a framework for addressing social competence in preschool that emphasizes strongly the role of the educator.
\nIn early childhood, play very often represents the context for the learning and expression of social behavior. A preschool-aged child’s social competence among same-aged peers can be conceptualized according to what takes place as children interact—in other words, how children initiate, sustain, and maintain a level of positive interaction or cooperation—as well as how they resolve interpersonal conflicts. While such a conceptualization focuses on an important sequence of typical events in the preschool classroom, it is also an oversimplification of this complex construct. Each of these components might involve many discrete social skills as well as underlying reading of social cues and situations.
As a result, many early childhood programs consider social-emotional development and its associated skills as critical components of the preschool curriculum. Whether or not extensive planned opportunities to learn social skills are planned, in a high-quality preschool classroom, adults engage in play-based learning activities alongside preschoolers, so the social problem-solving which occurs during play is critical for children to reap the developmental benefits that early education provides. Developing social competence and demonstrating positive relationships before children reach kindergarten not only enable children to approach a healthy trajectory of social–emotional development (by providing children with friends
What are these critical skills, and how do they operate and interact to produce social competence? First, it is critical to consider social competence within the context of each child’s broader ecological system. As illustrated in Figure 1, observed social competence (inevitably appraised by others) is the result of interaction between intra-child factors (such as brain development, temperament, self-regulation, and current developmental skills—including the impact of disability) and extra-child factors (caregiving, quality of learning environment and instruction, cultural and linguistic considerations). The interaction of these factors, as well as
Model of internal and external influences on social competence in early childhood [
The importance of others’ perceptions must not be underestimated, as these can create an environment of advantage or risk for children. For example, if a teacher is unfamiliar with the cultures of her students’ families, she may at best fail to address a critical realm of assets and needs and at worst categorize behaviors or preferences that are normal for children as somehow “problematic.” Likewise, if teachers are inexperienced in working with children with exceptionalities, they may be more likely to stereotype children or lower developmental expectations based upon their biases. The importance of perception can also be illustrated through social skills assessment (whether through systematic observation or norm- or curriculum-referenced checklists, all of which are frequently used in preschool). Teachers and caregivers may judge a child’s social-emotional development or competence quite differently simply because of typical differences between the school and home environments. These differences can be more effectively explored and understood when teachers form positive, collaborative relationships with caregivers. In this case, the educator is more likely to better understand how a child’s system of intra- and extra-child factors interact and make better instructional decisions.
\nWithin this system, many specific social skills are learned and employed by the child. Examples of skills associated with later success in school include initiation/sustaining social interaction, in addition to getting along with others, following directions, emotional self-regulation, solving typical social problems in ways deemed appropriate by others, and persisting through social challenges [5]. Focusing on these areas as a teacher not only helps individual children improve and develop them but may also improve the social environment of the classroom as a whole, providing a more developmentally appropriate learning environment for all children.
\nHelping young children to develop positive social skills and relationships is a critical responsibility for early childhood educators. This is particularly important for children with disabilities. At this point in time, however, the state of preschool in the United States paints a grim picture of the quality, appropriateness, and inclusiveness of classrooms in relation to children’s social and behavioral challenges. With thousands of preschool children suspended or expelled each year (on average, 250 per day), preschool programs wield punitive disciplinary actions at a rate higher than at any other level of education—up to three times the rate of K-12 in pre-K and as high as 13 times the K-12 rate in child care for 3- to 4-year-olds [6]. A portion of the explanation for such disturbing statistics lies in a failure of the system of early childhood education (including preparation programs, administrators/policy makers) to fulfill its obligation to support teachers in playing an active role in understanding and influencing the complex system illustrated in Figure 1. A lack of cultural responsiveness or awareness of bias, insufficient focus on developing relationships with families and children, a lack of supportive services or interventions, and a low investment in professional development and increasing the status, licensure, and compensation of early childhood educators are all relevant issues.
\nIn the end, the greatest influence on the success of young children in early childhood education is the educator himself/herself. The misinterpretation, rejection, and punishment of children with disabilities or developmental differences in the absence of inclusivity, supports, and developmentally appropriate interventions represent one of the key social justice issues of the field of early childhood education, particularly at a time when the majority of children under five do not have access to early childhood education programs to begin with. While these are clearly systemic issues affecting educators and not originally created by them, in many ways the teacher still holds the key to healthy, developmentally supportive, and inclusive classrooms.
\nFor a variety of reasons, many children fail to adequately develop key social skills, thus lowering their overall competence and placing them at risk for punitive discipline and failure in school. In particular, children with disabilities experience peer rejection at a higher rate and are much more likely to miss out on highly impactful social experiences with peers. This may be a result of differences between their social and play skills and those of typical same-aged peers and will worsen with time in the absence of high-quality instruction and/or support. Examples of such differences that are observable from a very young age (some behaviors present by infancy) include lower rates of social initiation, positive social behavior, appropriate responses, a higher rate of more disruptive entry to play activities and problematic behavior, and poorer turn-taking skills [7]. As a result, young children with special needs experience a high rate of social rejection, i.e., social isolation and rejection of play initiations [8].
\nDifferences and deficits in social competence in preschool-aged children are evident in children with many different types of needs (including autism, speech/language disorders, cognitive disabilities, and emotional and behavior issues, and developmental delay), as well as in children who placed at risk as a result of poverty, abuse, or engagement with child welfare agencies. Young children with disabilities tend to play with others less frequently and have fewer conversations than their typical peers; they may also lose social skills more quickly if teachers do not acknowledge these and encourage their consistent use [9]. As a result, such children are presented with fewer natural opportunities to develop and test out their social skills. For example, if it takes a particular child twice the number of peer interactions to learn an important skill (such as imitating and expanding on a peer’s play), but she has only half the opportunities due to isolation from or rejection by peers or adults, serious consequences for her social development may result.
\nEnsuring that the preschool classroom provides effective, systematic, and developmentally appropriate instruction to support children’s social competence requires collaborative planning, instruction that is informed by assessment, and targeted strategies that are implemented throughout the year. All of these dimensions of instruction must be provided in a high-quality learning environment that is inclusive of all children and supported by teaming and professional development.
\nA first step in effectively addressing social competence involves reaffirming one’s commitment to the inherent inclusiveness of the field of early childhood education. Developmentally appropriate practices, or DAP, as defined by the NAEYC place a high value on the developmental knowledge of teachers and their understanding of the milestones and key goals of the preschool years [10]. But instructional decision-making involves two other components which are intended to hold equal weight in determining the extent to which one’s teaching practices are developmentally appropriate. First, educators must consider a child’s individual interests, abilities, and developmental progress. Subsequent planning must take into account the inside out factors included in Figure 1 at an individual level—in other words, planning for the interests of young children is not sufficient and is not considered developmentally appropriate practice unless the interests and needs of each and every child are considered and integrated. NAEYC’s guidelines also stress that educators must consider what is culturally important to children and families, thus supporting their belief systems and practices. This does not mean that the classroom must mirror the home but rather that teachers (particularly when their backgrounds differ from those of the children they teach) examine the ways in which their backgrounds and biases influence their teaching aim to develop more empathetic, trusting relationships with children and families [11]. It is from these relationships that more meaningful antibias materials, activities, and teaching practices must be embedded, rather than through simply acknowledging diversity. This way preschool educators are more likely to begin the work of sustaining children’s and families’ culture rather than simply acknowledging it [12]. Culturally sustaining practices reject the notion that family culture can be subsumed or subordinated within a classroom or school culture and are actually reflected in NAEYC’s DAPs which state the families should partner in curriculum planning and child assessment (see [10]). These guidelines are much more inclusive of diverse children and families than many educators may realize.
\nIn one sense, the majority of programs serving preschool-aged children already have an inclusive structure. Head Start programs are required to serve a proportion of children with disabilities, just as they are children from households considered low income, and preschool programs funded by states must serve children aged 3–5 with disabilities in the least restrictive environment. Diversity is the everyday reality of the preschool classroom, and many of the practices that support successful inclusion also support not only children with disabilities but also those who require support to develop social competence in preschool. They include [13]:
Responsive instructional practices, aligned with DAP’s three principles, which respond to children’s interests, motivation, and lives outside the classroom
Proactive environmental and instructional accommodations which ensure the access to and understanding of the curriculum for children with widely varying strengths, needs, and approaches to learning
Classroom communities that actively support cooperation through explicit and responsive teaching of skills with value beyond isolated classroom situations
Classroom activities that involve heterogenous grouping, jointly planned and including the input of all key members of the early childhood program community
When children with identified disabilities are included in the preschool classroom, these four sets of practices provide a strong supportive context for better inclusiveness of the classroom as a whole and for addressing individual needs. The Individuals with Disabilities Education Act (IDEA) and its subsequent amendments mandate services for children aged 3–5 with disabilities within the least restrictive environment (LRE), which is defined as the educational environment as close to where nondisabled same-aged peers would be served as possible. In states where this results in a higher percentage of children with disabilities in general education classrooms for the majority of the time, the use of punitive disciplinary measures is lower. This means that collaboration to further the inclusive aims of IDEA through the classroom practices described above further provides a potentially direct remedy to the social justice issue of excessive suspension and expulsion of preschoolers.
\nInstructional strategies for addressing social competence include embedding the teaching of social skills in each day’s classroom routines and activities, as well as more explicit teaching of specific skills. Common social skills emphasized in early childhood curricula include those presented in Table 1 below [14].
\nSkill area | \nSocial skills | \n
---|---|
Emotional understanding and empathy | \nCommunicating emotions to others Expressing emotions in adaptive ways Recognizing that one’s actions affect others Acknowledging and responding to others emotions | \n
Initiation of play | \nInitiating social interactions Entering others’ play Responding to the initiations or invitations of others Managing impulses through self-control | \n
Maintaining social interaction | \nTurn-taking Engaging in parallel play Making attempts at cooperative play | \n
Social problem-solving | \nCoping with the inevitability of limited resources (e.g., materials/manipulatives) Communicating a social problem Cooperating in talking through a social problem Accepting and acting upon potential solutions to social problems Making choices that defuse or prevent conflict | \n
Social skills emphasized in the preschool classroom.
An initial step to addressing social competence in the preschool classroom includes identifying the skills that most children need to work on and ensuring that universal teaching strategies address these throughout the day. For children who require additional support or a greater number of opportunities to work on a particular skill, embedded teaching provides a framework for planning (e.g., [15]). Embedded teaching involves examining the daily routine and its varied learning activities and identifying wherein specific group or individualized outcomes may be addressed. In this sense, it combines accommodations for diverse children and targeted teaching strategies within a naturalistic approach that does not require significant individualized intervention or time away from the other priorities of teaching to accomplish. For instance, a teacher might intentionally model and teach skills such as requesting, questioning, commenting, and sharing while partnering with children in pretend play in the house area based upon the needs of particular children there and because that center provides a meaningful context within which to embed the teaching of those skills. In this sense, the teacher takes advantage of these natural opportunities, acknowledges children who use these behaviors, and narrates intentionally to highlight their presence and importance. The teacher then may help younger peers who do not yet demonstrate those social skills to respond positively and to perhaps attempt the skills themselves with support. Everyday routines such as meals and snack times present another set of natural opportunities within which to embed the teaching of social skills such as greeting, conversational turn-taking, requesting and saying “thank you.” Mealtimes also offer an opportunity to address and normalize children’s varied cultural practices in relation to food. In inclusive classrooms, teachers systematize the identification and use of these natural opportunities, while also identifying skills for which more explicit lessons or activities may be needed. Note that in embedded teaching, the center/routine/activity may lend itself to certain forms of social interaction, but the teacher engages in active planning to both maximize the benefit of these opportunities and make room for additional ones. While this does require flexibility and in-the-moment responsiveness, it also requires that teachers (a) recognize key group and individual social-emotional needs, (b) understand that children in the naturally occurring and planned groups of the preschool day (as opposed to children who seem to be isolated or independent) will benefit from embedded teaching, (c) proactively plan across the daily routine, and (d) consider and select the best ways to deliver social supports within a variety of contexts. In this sense, it goes beyond intentional interaction because it is both targeted and preplanned.
\nOur understanding of the benefits of social competence and the risks associated with a lack of it is generally better understood than the use of supports and teaching strategies in the preschool classroom. While a variety of curricula, activities, assessment tools, and intervention strategies have been developed, none of them have an evidence base that encompasses the diversity of children, families, program models, or unique learning needs/disabilities preschool educators must navigate. Widely adopted early childhood curricula (such as The Creative Curriculum) and approaches (such as HighScope) include social-emotional goals, objectives, and/or indicators (i.e., specific skills) that can guide instruction in preschool classrooms. The explicit instruction of these skills takes many different forms. In The Creative Curriculum, teaching activities include what could be called embedded teaching focusing on social-emotional goals and objectives in children’s play at various classroom centers. However, specific guidelines as to how to teach particular skills are lacking. In the HighScope approach, social and emotional indicators are assessed and planned for, and a hierarchy of strategies to support child-directed active learning is included. In addition, a specific model for intervening and supporting children to problem-solve through common conflicts is provided. It does, however, rely upon the existing skills of children to navigate its complex steps, which can take years to master.
\nIdentifying high-leverage social skill instructional approaches within these approaches is challenging at best, as teaching strategies are typically employed within their curriculum frameworks. While evidence suggests that both of the approaches mentioned above demonstrate some effectiveness in improving overall developmental outcomes for young children, an evidence base for specific teaching strategies within those approaches is lacking. Nevertheless, certain commonalities across these approaches can be identified, representing a survey of common “best” practices. These include:
In context, strategies such as these can effectively dovetail with the teaching of many other skills in the preschool classroom, and they can be particularly necessary in inclusive classrooms where the input, support, and prompting of the teacher may be necessary in order for interaction to occur (or occur successfully). Preschool educators should keep in mind that teacher-directed and structured activities to address social skills represent only one aspect of a healthy learning environment where positive relationships and a sense of community are developed. Explicit instruction of social skills works best in classrooms where children are offered a sufficient amount of freedom and choice and where activities and materials emphasize shared control between adults and children.
\nWhere children with disabilities are present, a single approach certainly will not meet the needs of all children. Many children with disabilities benefit from basic classroom accommodations and seek out social interaction with peers, while other children may need more specialized, individualized social skill supports provided by their individualized education plan (IEP) teams, including special education professionals. Preschool educators must understand children as individuals rather than as members of a perceived disability category. By observing such children, learning their interests, preferences, and sources of motivation, as well as their experience/degree of success in social interaction and more informed decisions, can be made as to how children with disabilities will respond to existing practices and whether more targeted social skills interventions may be necessary. But it is always better for such interventions to be delivered within positive nurturing relationships with skilled and understanding adults who appreciate that social competence is part of a complex ecological system rather than simply a characteristic of children to be simplistically judged by others.
\nIn diverse preschool classrooms, play-based learning and social relationships form an important piece of the foundation of social development and influence later academic achievement. At the same time, the consequences of disabilities in early childhood and/or insufficient or inappropriate social behavior destabilize that foundation. Over time, these differences and deficits predict negative outcomes such as emotional and behavior problems, disciplinary action, and school dropout. In other words, the social and behavioral challenges faced by many children with disabilities worsen over time in the absence of intervention. In this sense, social competence interventions may be viewed as essential forms of both intervention and prevention.
\nInterventions of various types are available to improve social skills in early childhood, including increasing the frequency and quality of specific skills and enhancing social pragmatic skills (which include both the verbal and nonverbal behaviors associated with interactive and cooperative play). What remains to determine is whether these interventions produce effects across contexts that are long-lasting and that make an impact on meaningful social behaviors and social competence rather than simply increasing the instance of isolated skills. Studies examining these factors are greatly needed, as well as ones that include the perspectives of peers and caregivers within a more context-specific model of social competence.
\nSocial skill interventions generally fall into one of four categories: systematic arrangement of the classroom environment, behavioral strategies, instructional approaches, and combined approaches (which utilize elements of two or more of the above). These interventions share many features with the universal instructional strategies discussed earlier in this chapter. What distinguishes interventions from such strategies is a set of practices that includes (a) predetermined decisions about the frequency, intensity, and duration of the intervention; (b) a matching of the intervention to identified individual or group needs; (c) the use of assessment tools to establish skill performance levels and track progress; (d) goals identified either from individual children’s IEPs or by analyzing data on current levels of performance. Interventions ideally also have an evidence base supporting their use; however, preschool teachers frequently do not have either the resources or the preparation necessary to access and evaluate such evidence. Interventions may also be embedded into multitiered systems of support (discussed later in this chapter).
\nSystematic arrangement of the classroom environment, sometimes referred to as environmental arrangements [16] or structured play, is a means of more effectively facilitating social interaction (e.g., altering the size, arrangement, or materials at a center to perhaps facilitate more cooperative play). Such strategies are the lowest intensity form of social competence intervention, and virtually no evidence base exists in the literature verify their effectiveness. However, environmental arrangement is an important consideration for educators as they design more direct and intensive interventions.
\nBehavioral strategies again use cues, prompts, and positive reinforcement to increase interactive social and play behaviors. As part of a systematic intervention strategy, they can be effective in increasing the social behavior of children with autism spectrum disorder. They can involve peers and occur across contexts, allowing for greater generalization. An example of a behavioral intervention might involve peers in increasing opportunities for target children’s interactive play. Peers are positively reinforced for following through on-stated plans for social play that include choosing target children as playmates. A key consideration in behavioral strategies is that they are usually focused on specific behaviors, while the context of social competence is quite complex. Careful monitoring is essential to ensure that behavioral strategies are part of a systematic approach that increases desired behaviors, decreases undesirable ones, and addresses competence as a whole. As an example, an intervention that focuses on initiations may be successful in getting children to interact, but without focusing on the complexities of maintaining positive interactions, such interventions, can lead to increased conflict among children without consistent adult monitoring and attention to additional social competence dimensions.
\nInstructional approaches include any intervention involving the direct instruction of children in specific skills such as sharing, helping others, and initiating social interaction (e.g., [17, 18]). These preschool social competence interventions have the strongest evidence base for children with special needs and involve teacher-led social skill activities followed by supported play. In other words, using a variety of strategies, teachers help children to learn and master the skills, including offering support during the times when children have natural opportunities to use them. In some cases, teachers may directly teach social behaviors (such as greetings or requests for toys) and then follow up during play. For example, at circle time, a teacher and children sing a new song about inviting others to play. She then follows the children into the learning centers, watches and listens as some children try this new behavior, and supports children who are playing alone, but seem ready to learn to invite a friend to join them. Some children might respond to a prompt; others might need the teacher to model what to say and do. Such adult-mediated instructionally-based social competence interventions can have a significant positive effect on the social competence of young children with special needs when offered in naturalistic settings. Given that instructional approaches are the most widely studied and that these may be integrated into existing classroom activities across a wide variety of settings, the potential for their utility in inclusive classrooms is great.
\nThe use of social skill interventions with preschool-aged children is well supported in published research, with a variety of programs showing a positive impact on specific skills in both specialized and inclusive settings. Some of the positive outcomes include increased social language and play initiations, and decreased maladaptive behavior, and increased overall competence as observed by adults. But while published research appears to indicate that these interventions have a generally positive relationship with various social skills and other behaviors associated with social competence, many questions regarding their impact on overall competence remain unanswered. The impact of social competence interventions has been found to vary across variables such as gender, age groups, risk factors, and disabilities. There are no consistent guidelines regarding intervention length and intensity, type of interventionist, treatment integrity, and presence of follow-up. Few of these variables have been explored sufficiently.
\nWhat remains to debate is whether these interventions produce effects
Social competence can be integrated into multitiered systems of support [19] that (a) organize common approaches as classroom-wide (universal), naturalistic (targeted), and explicit (intensive) [20]. Considering available interventions through this three-tiered lens is an essential step in aligning practice with the federal law. Some include social skill curricula as a universal intervention at the first of three tiers of support. Other approaches such as the Pyramid Model [21, 22], which is now in use in 29 of the United States, offer a comprehensive model including coaching and professional development effectiveness in both increasing social skills and addressing behaviors that interfere with preschool children’s learning and relationships. The Pyramid Model emphasizes professional development in evidence-based practices, as well as nurturing relationships and a healthy, developmentally appropriate classroom environment as the foundation of preschoolers’ social-emotional development. This implementation of social-emotional supports and interventions represents the top levels of the pyramid, which was designed to complement the tiers of response-to-intervention models while adapting them to address the realities and needs of the field of early childhood education (including children under age three). Such models not only hold great promise in terms of positively influencing the social competence of children but also create networks of support, resources, professional development, and data that will continue to bear fruit as they are even more widely implemented.
\nFigure 2 is designed to place such models into context, as they address only part of a broader realm of need in the early childhood field. First and foremost, increasing the amount and depth of teacher preparation in this area is critical. Innovation in teacher education has moved from the university classroom to field-based preparation embedded in mutually beneficial partnerships with early childhood education programs, and it is in these field-based apprenticeships that the awareness, relationships, and practices to address preschool social competence must be learned and developed [23]. The merging of professional preparation and development provides an essential opportunity to learn, practice, and reflect critically upon practices as they are designed and implemented with diverse children. In this sense, the obligation of culturally sustaining teaching practice becomes the everyday work of the teacher candidate (rather than an abstract notion to be faced upon entry to the field), with support from faculty and practicing teachers.
\nInterrelated factors promoting preschool social competence.
Through supported reflective practice and experience with children and families, preschool teachers can grow to understand the complexity of social-emotional development and all of the factors influencing social competence, as well as the role of the educator and the early childhood program in teaching and intervening to influence positive outcomes. Through empowering teachers to understand and work within this complex system, successful inclusion and an inclusive philosophy are born. At this point, a critical lens on discipline and punishment of young children widens, and comprehensive-tiered systems and the interventions therein may flourish. In this sense, all key players in the preparation, support, and everyday work of preschool educators have a role in promoting social competence for each and every child.
\nChildren who have positive relationships with peers in inclusive classrooms become accustomed to play with children of varying ability levels and may carry their inclusive experiences and perspectives as they move forward into K-12 education, which represents a meaningful, long-lasting impact on our field and the children and families served within in.
\nPreschool provides key opportunities to understand and influence the social competence system on which many aspects of future development are based. Teachers in inclusive classrooms can strengthen this foundation by engaging in culturally sustaining practice, directly teaching a variety of social skills in accordance with or alongside the preschool curriculum, utilizing inclusive practices and interventions to avoid or defuse punitive practices, and by engaging in collaborative and tiered systems of professional development, support, and intervention.
\nWithout sufficient preparation, professional development, and the integration of intervention efforts in collaborative systems of teacher, child, and family support, preschool educators are not likely to meet the social competence needs of all children in inclusive classrooms. Teacher preparation must more strongly emphasize these teaching and intervention skills, so that preschool educators feel confident prompting, supporting, and further developing children’s social behaviors so that inclusion programs can be successful. Teacher preparation programs can accomplish this in several ways. First, by emphasizing meaningful community partnerships, programs can better align the aims of field-based teacher preparation (see, [23]) with those of early childhood programs—in other words, by focusing teacher candidates’ time in classrooms on making a positive, measurable impact on the development (including social behavior) of children. Next, through supported practice under constant faculty supervision, candidates can successfully succeed at teaching and intervention practices that are particularly challenging to enact in practice (including addressing challenging behavior and improving social competence across people and settings). Finally, by aligning these preparation activities with professional development offered within mutually beneficial partnerships, preparation programs and early childhood education programs create a shared culture of trust and growth.
\nSewage sludge (SS) is formed as a by-product at a wastewater treatment plant (WWTP) and represents a heterogeneous mixture. This complex suspension consists of solid organic and inorganic substances and colloids, which have been separated from the wastewater during the treatment process [1]. The global production of SS is estimated at 45 million t of dry matter per year [2, 3]. During the last decade the SS production in EU countries increased by 1.5 million t of dry matter (DM), that is, from 11.5 million t in 2010 to 13 million t in 2020 [3], therefore, its management is a problem of great concern. The SS disposal reaches up to 60% of the total operating costs of WWTP, and, hence, makes this process problematic and expensive [4].
Sludge from WWTP is recovered by compost production, the application directly to agricultural and forest land, production of growing substrates, and energy recovery [5]. For practical and legal reasons, SS is increasingly reused rather than landfilled. This approach aims to minimize generated waste and promote the development of the bioeconomy that provides intelligent waste management, and, hence, is consistent with zero-waste strategy [3, 6]. Different countries have chosen different strategies for the use of urban SS. Analysis of the Eurostat data in the period from 2014 to 2018 showed that the use of SS in agriculture, in combination with compost, had been the main route for sludge disposal in the EU with 44.58%, followed by incineration (32.70%) and other methods of disposal (9.16%). Landfill disposal was at the level of 7.81%. Comparing the costs of different sludge disposal methods, the application on land and agriculture involves the lowest cost compared to composting, drying, incineration, and landfill.
At WWTPs, with more than 10,000 inhabitants, the sludge is divided into primary and secondary sludge. The primary sludge contains settling substances (from primary settling tanks), usually, it has a granular structure. Secondary sludge, also called excess sludge, consists of a mixture of microorganisms and settable substances from the biological stage of the WWTP. Primary sludge and secondary sludge are referred to as so-called raw sludge. The raw sludge is still microbially active, it can contain pathogenic microorganisms, with the total content of organic substances in the dry matter at about 70%. However, dewatered sludge (20–45% DM) is considered harmless and suitable for agriculture, because of high content of organic matter and biogenic elements (C, N, P), which increases soil fertility and is essential for plant growth and development as well as for soil microbiota [1]. Therefore, the use of SS on agricultural land is the best way to recycle the nutrients it contains, thus making the SS an important biological resource for sustainable agriculture [7, 8, 9]. On the other hand, the application rate is of great importance. Excessive concentrations of plant nutrients, mainly nitrogen and phosphorus, can also harm the environment, especially inland waters.
Another important issue is related to the abundance of hazardous and very persistent substances, such as heavy metals, polycyclic aromatic hydrocarbons, polychlorinated biphenyls, halogenated hydrocarbons, polychlorinated dibenzo-p-dioxins and dibenzofurans, pesticides, personal care products, hormonal substances, drugs and their metabolites, microplastics, and nanoparticles [8].
Therefore, the incorporation of sludge and its compost in the soil is regulated by various legislative acts [9]. The annual emission limit values for dry matter, heavy metals, total nitrogen, and total phosphorus are the maximum mass of these substances that can be applied per hectare of sludge or compost on average per year. Emission limit values for sludge dry matter vary considerably between the EU Member States, ranging from 1 to 10 t ha−1 per year. According to Mercl et al. [10], a high rate of SS composts applied once (60 t ha−1 compost in seedbed) is not recommendable since high nitrate concentration is not taken up by maize and increases the leaching risk. Furthermore, SS commonly contains high amounts of human pathogenic bacteria excreted in feces and urine, so the SS should be appropriately hygienized before application in agriculture.
The aim of this chapter was to summarize the main aspects of SS treatment for its application in agriculture, with emphasis on process efficiency, safety, and feasibility. The dual role of SS as a fertilizer and amendment in the soil is widely described in the literature, referring to the supply of nutrients to plants and improving the soil’s physical conditions, respectively. Our own results on SS treatment have been incorporated into the review of recent scientific literature and legislative documents.
Sludge is rich in organic matter, nitrogen, phosphorus, and other macro and microelements, which makes it a useful raw material to be used in agriculture. Dry SS contains on average 50–70% organic matter and 30–50% mineral components [8]. Physicochemical and biological characteristics of agricultural soils, which are amended with the organics-rich SS, can be considerably improved. Particularly, a reduced bulk density leads to an increased soil porosity and soil-air recirculation, as well as improved soil structure and water holding capacity. Besides, the concentration of soil humus is increased. Organic matter of SS enhances soil nutrient storage, soil biota, and diversity, as well as reduces exposure to erosion. High organic matter content facilitates the formation of stable organic complexes with humic acids, thus reducing metal availability [11]. A slow release of mineral elements from SS to soil also changes the physical, chemical, and biological parameters of soil and benefits from increased gas exchange, better water infiltration, and its retention. The compounds of SS are available for a longer period [12].
Mbagwu and Piccolo [13] found that the decomposition of organic materials in sludge enhances the availability of nutrients such as nitrogen and phosphorus substantially. Application of SS at a rate of 200 t ha−1 increased the total nitrogen of soil aggregates by 57% and available phosphorus by 64.2%.
The formation of organic and inorganic acids throughout the decomposition process of SS components under aerobic conditions increases soil acidity. Soil salinity positively correlates with the increased application rate of SS. Amendment of loamy-clay soil with SS at dose 60 t ha−1 increased soil carbon content from 0.16% to 1.45% [14].
Comparison of physicochemical characteristics of SS of different origins showed that average concentrations of nitrogen, phosphorus, and potassium are similar and reach up to 3.20%, 1.75%, and 0.5% per kg of treated dry SS, respectively [15, 16, 17]. Often the potassium content in SS is considered insufficient for plant nutrition [8]. Some studies indicate that SS is an efficient replacement for chemical fertilizers, especially phosphorus. Indeed, Switzerland, Germany, and Austria are developing legislation to make P recovery mandatory from municipal SS [18, 19].
Nevertheless, there are some site-specific factors (e.g., applied technology, quantity, and the origin of raw wastewaters, which differ by the composition of macro- and microelements and risk compounds), that make each SS unique, hence this specificity must be considered to predict the outcome of SS treatment. Determination of these factors remains challenging [20].
The management of SS in the EU is regulated by various legislative acts. The Directive 2008/98/EC establishes the fundamental ideas and terminologies, such as waste, recycling, and recovery [21]. It explains the basic concepts of waste management, the distinction between waste and secondary raw material (“end-of-waste criteria”), waste, and by-products. The directive lays down basic principles of waste management without adversely affecting human life, health, nature, and the environment. Waste legislation and policy of the EU Member States shall apply as a priority order with the waste management hierarchy (Figure 1).
The Waste Framework Directive 2008/98/EC priority order with the waste management hierarchy [
SS dose/soil | Plant species and effect | Reference |
---|---|---|
Field experiments | ||
8.3% w/w/clayey–silty | Yield increase by mulching 65.7%, by mixing 91.5%: wheat ( | [78] |
15, 30 and 60 t ha−1/Entisols | Grain yields at the 1st year less than mineral fertilizers by 3–5%, 2nd year increase in average by 13.8%: corn ( | [12] |
20 t ha−1/clayed soils | Grain yield increase by 71–171%: wheat ( | [79] |
25 t ha−1/n.d. | Yield increase by 43.5%: radish ( | [80] |
30 t ha−1/n.d. | Yield increase by 26%: sunflower ( | [81] |
40 t ha−1/sandy clay loam | Grain yield increase by 91.6%; 1000-grain weight increase by 26.9%; number of productive tillers by 51.4%: wheat ( | [82] |
80 t ha−1/calcareous soils | Head yield increase by 186%: lettuce ( | [83] |
150 t ha−1/n.d. | Increase by 42.3% in comparison with control, decrease by 31.8% in comparison with RDMF, that is, 45.5% and 22.1%; 46.3% and 18.9%; 51.6% and 27.8%; 52.1% and 8.5%; 35.5% and 16.2%: carrots ( | [84] |
250 t ha−1/mudflat saline-alkaline soil | Biomass increase by 399.7% (control 1.3 t ha−1): sweet sorghum ( | [85] |
Vegetation pot experiments | ||
40 t ha−1/loamy clay (calcareous) | Increase of DM up to 5%: barley | [86] |
30 t ha−1/alluvial soils | Seed cotton yield (71.4%), lint yield (67.7%), and cottonseed yield (74.1%) were increased: cotton ( | [87] |
300 t ha−1/mudflat soil | Fresh weight of aboveground parts and roots increased by 555 and 128%, respectively: ryegrass ( | [88] |
15 and 30%, v/v/peat-based medium | Pepper yield and the number of fruits per plant increased by 28–43 and 30–98%, respectively: pepper ( | [89] |
50%, 100%, and 150% of RDMF | Total sugar and sugarcane increased by 4.68 and 4.19%: sugarcane ( | [90] |
50 and 100%/soil loamy chernozem | Chlorophyll b (15–38%), carotenoids (5–50%) increased, while plant fresh weight (100%) SS was decreased by 8%: Sweet basil ( | [91] |
8.7 g L−1 + MF/loamy sand | Yield increase by 15%: corn ( | [73] |
10, 20, 30, and 40 g kg−1/n.d. | Seed germination rate increased by 9.6, 19.0, 28.6, and 28.6%, respectively, total biomass increased by 146, 236, 278, and 400%: broad bean ( | [14] |
Plant growth in response to the presence of SS in soil.
RDMF: recommended dose of mineral fertilizers; MF: mineral fertilizers.
An ex-post evaluation of the SS Directive 86/278/EEC in 2014 showed that its initial objectives were achieved, in spite of large variations in the amount of SS used in agriculture in the Member States (from none to well over 50%) [21, 22]. Currently (2020–2021), the EU initiated an evaluation of legislation efficiency, as well as the risks and opportunities of SS used in farming [23, 24].
Furthermore, two EU working documents on sludge have been produced: the EU Working Document on sludge (2000) and the EU Working Document on sludge and biowaste (2010). The EU Working Document on sludge (2000) indicates that to be used without restrictions, sludge should undergo an hygienization process by an “advanced treatment,” which should result in at least a 6-log-unit reduction in
According to the EPA Environmental guidelines published in 2000 on stabilization of biosolids products [26], a biosolids product must meet at least one pathogen reduction requirement and at least one vector attraction reduction requirement [27]. Stabilization Grade A includes thermally treated biosolids (at least 50°C), high pH-high temperature process and biosolids from unknown processes, while stabilization Grade B—anaerobic digestion, aerobic digestion, air drying, composting, lime stabilization, extended aeration, and other processes accepted by the EPA products [26].
In the context of sustainable development principles some main components, which determine the rational solution of the multi-faceted problem of municipal SS, must be considered. Poor farming practices combined with the overuse of chemical fertilizers on poor soils have caused a negative environmental impact, which leads to the degradation of arable land. The effort to increase productivity by increasing the use of various chemicals in fertilizers further diminishes soil fertility. With each harvest, the soil loses organic compounds, and permanent aggravation of improper agricultural practices often prevents the land from recovering. World chemical fertilizer consumption increased from 70.95 kg/ha in 1976 to 138.16 kg/ha in 2016. And in some regions, the fertilization dose increased up to hundreds and even thousands of kilograms per hectare (Figure 2) [28].
Fertilizer consumption by different countries and regions. (a) Data on some countries and regions with fertilizer consumption below 500 kg/ha; (b) data on countries with rapid growth of fertilizer consumption, which exceeded 500 kg/ha [
The quantity of organic elements in the soil constantly decreases. A significant part of the SS does not return to the soil, but is disposed into the sea, is incinerated, or is subject to other different kinds of destructive effects, leading to drastic decreases in soil fertility and continuous soil degradation.
The quantity of the SS constantly increases. The peculiarity of SS lies in its multi-mineral compound and a huge range of organic matter; in fact, the SS is a nitrogen-phosphorus-potassium organic fertilizer, containing a full set of microelements necessary for the growth of crops. However, due to the high risk of pathogenic impact, a huge part of human and material resources is directed to the destruction of this important resource.
The overwhelming majority of the SS disposal methods are expensive, harmful, or contain both factors. Most municipalities face the growing problem of wastewater treatment. In many cases, waste is dumped into landfills, oceans, or incinerated. The rational solution to the problem of municipal SS disposal lies in an integrated approach to returning the sludge into the agricultural cycle [29].
The directive introduces the “polluter pays” principle and the extended producer responsibility. Some existing projects of producing energy, for example, biogas, minerals, and chemicals out of the sludge, do not prove to be sustainable and viable financially. Furthermore, in most cases, most of the sludge is eventually dumped at the end of the process. Incineration represents the total elimination of the sludge but is extremely expensive. It seems to be the most rational to consider SS not as a problem, but as a valuable resource.
In recent years, out of concern for the profound soil degradation, a growing trend of shifting to organic fertilizers is taking over within the agricultural industry.
The global fertilizer market was valued at around $360 billion before the COVID-19 pandemic with organic fertilizer making up just $6.8 billion. The organic fertilizer market is described as steadily increasing and expected to post a CAGR (Compound Annual Growth Rate) of 14% during the period 2019–2023, with the key factor being increased food demands and agricultural shortages due to population growth and climate change [30].
In case of the continuing negative influence of the high transport, logistics, and energy costs, the SS processing can offset the lack of fertilizers through a domestic product that costs only a fraction of the price to make, creating a local commodity with a considerable economic edge.
Sewage sludge is a natural epidemic focus, and the detection of SARS-CoV-2 in fecal masses led to the long-overdue conclusion to strengthen human health protective measures and counteract the emergence of epidemics [31]. The necessity of the implementation of new biological safety criteria can have a significant economical and long-term structural influence on the development of the entire sphere of processing and use of SS. For instance, regarding the sediment formed during the epidemic, it is recommended to avoid its traditional aerobic composting. At once, in the sludge undergoing thermal disinfection treatment, the risk of infection with SARS-CoV-2 is considered in the range from low to negligible [32]. Intensive decontamination measures will make the product more expensive, but more in line with the requirements of sustainable development.
To prevent potential biological threats toward the environment and human health, it becomes increasingly important to develop the most isolated from the environment hermetic methods for the SS disposal, without destroying the organic component, valuable for agriculture.
Economic aspects of SS hygienization have been analyzed [33]. The energy requirement per 100 tons of sludge was estimated depending on different disinfection conceptions. Thus, solar dehydration and chemical treatment with alkali consume 11.7 and 148.3 kW h with the production of 80 tons and 99.6 tons, respectively. In turn, the most expensive technology is gamma irradiation, which consumes 64,800 kW h for obtaining 97.6 tons of the product. The thermal drying also requires quite a high energy consumption, that is, 21,000 kW h for 20 tons of product. The composting does not consume electricity [33]. The high costs of thermal hydrolysis and ultrasonic methods and the need for a neutralizing agent in acid solubilization limit the rapid implementation of these processes in industrial practice [34].
Our testing of the infrared heating method for SS disinfection demonstrated successful results. It took 15 min for the material with an 80% humidity, including the time it required to heat the layer to 95°C, which is below the temperature at which the organic matter decomposes [35].
The widespread usage of SS biomethanation has resulted in the building of a number of complex installations that combine biological wastewater treatment facilities with anaerobic digesters. The development of digestate-derived granulated soil fertilizers is based on physicochemical processing of biostabilized sludges, in keeping with the circular economy concept and the concept of “waste-to-product” [36].
In this respect, the costs of pretreatment technologies for SS biomethanation with further conversion of digestate to fertilizers should be taken into consideration. The estimated energy utilized for the mechanical operations during SS disintegration and anaerobic digestion (stirring and pumping) was calculated to be 1253.6 kW h per ton [37]. The energy spent for SS pretreatment may vary depending on the solubilization [38], used consumables [39], and methods [40]—thermochemical (TC), sonic, thermo-chemo-sonic, etc. It is experimentally proven that combined disintegration pretreatment should be more efficient. The energy consumption for TC sludge pretreatment (30% solubilization) for biogas production was calculated to be 1588.552 kW h per ton of sludge. The thermos-chemo-ozone (TCO3) pretreatment can optimize the total energy input up to ~721.766 kW h per ton [41].
The evaporation of water should be weighed out between the energy costs in the process and the SS management costs without drying [42].
According to the economic feasibility review of our project for fast SS recycling into biological fertilizers, the energy cost will be nearly $30 per ton of fertilizers (with its humidity ~50% and energy costs $0.1 per kW h and initial SS humidity ~80%). The tested method allows providing 1 ton of bio-pathogenic-free fertilizers due to utilizing up to 1.5 tons of SS and withal avoid other SS disposal costs (Figure 3) [43].
Technology of the fast recycling of SS into organic fertilizer. Methods are according to Chukurna et al. [
The applied methods and technical decisions have international priority under the Paris Convention for the Protection of Industrial Property, the World Intellectual Property Organization (WIPO) Eurasian Patent Organization (EAPO) and national patent organizations.
Stabilization of SS aims at reducing some disadvantages of SS (e.g., odor, leaching of heavy metals, etc.), thus considerably extending the potential of SS application. The extent to which readily biodegradable organic matter has degraded is referred to as the degree of stability [44]. Mixing of SS with fly ash, lime, peat, clay, straw, and other residues considerably improve SS characteristics, reducing leachability for metals and soil loss [45, 46]. The addition of wheat straw to the bioaugmented SS after 16 days incubation demonstrated the highest and most stable respiration intensity, the lowest ammonia emission, and the highest stimulation effect on the cress seedling growth, as compared to other treatment types [47].
Santos et al. [22] compared the performance of six residues serving for (i) sludge drying and (ii) improving agronomic properties of the final product. Weathered coal fly ash, bottom biomass ash, green liquor dregs, lime mud, eggshell, and rice husk were chosen as adjuvants based on circular economy and industrial ecological parameters. (0.15 g adjuvant/g SS wet basis). The addition of bottom biomass ash to SS promoted the highest diffusion coefficient and drying rate. The highest positive effect on agronomic parameters was shown for the SS amended with eggshell. Among evaluation criteria were acid neutralization capacity, oxygen uptake rate, and germination index [22].
Sludge treatment technologies for preparing a valuable fertilizer must meet legislative criteria on sludge hygienization. Numerous technological approaches on SS treatment, which were conducted at ambient temperature or under mesophilic conditions, had a strong effect on biological liquid sludge stabilization and natural dewatering and drying technologies, although disinfection efficiency was unsatisfactory [48, 49, 50]. In this respect, further comprehensive research on SS treatment should be focused on a combination of different physical (especially, thermal) and chemical processes, which would convert SS into a qualitative fertilizer with safe microbiological characteristics. Figure 4 summarizes a broad spectrum of methods for SS disinfection. Several studies have experimented with hybrid methods where two or more technologies can be integrated to increase treatment efficiency and performance [62].
Methods of sludge disinfection. Combination of different methods is indicated by asterisks of the same color. By Izydorczyk et al. [
The disinfection approaches should be optimized to minimize potential adverse impacts, such as antimicrobial resistance [62]. Another inherent problem with all sludges rich in nutrients is pathogen regrowth. Offensive odors serve as indicators of microbial regrowth because they are produced as bacteria break down proteins and other organic compounds containing nitrogen and sulfur [63].
The SS is characterized by a great microbial diversity, which may vary depending on the origin of sewage, its treatment, and industrial activity. Microbial activity in SS, transformation by-products, and residues may impact soil quality if SS is used as fertilizer/amendment [64]. The number of different groups of indicator microorganisms in 1 g of raw SS (wet) on average is 102–103 for Salmonella (bacteria), Enteroviruses (viruses), Giardia (protozoa), and Ascaris (helminths), while 106 – for bacteria
Many factors modulate microbial community structure within SS, which may change from autotrophic to heterotrophic bacteria depending on the effluent source. According to Nascimento et al. and Nielsen et al. [64, 66], Proteobacteria phylum (21–65%) is predominant in municipal SS. This phylum was primarily dominated by Betaproteobacteria that represents bacteria involved in organic matter degradation and nutrient cycling. Bacteroidetes, Acidobacteria, and Chloroflexi were among the less prominent species. Our recent experiments have also revealed Proteobacteria to dominate in the raw SS (60.17% reads), which consisted of 16.40%, 29.18%, and 12.33% of Alphaproteobacteria, Betaproteobacteria, and Gammaproteobacteria, respectively. At the genus level, the most abundant were Streptomyces (5.68%) and Pseudomonas (3.48%) (Figure 5A) [47].
Relative abundance of microorganisms in sewage sludge. A—at the genus level with relative abundance ≥1% (29% from the total reads); B—
Considerable changes in the microbial community structure of SS occur during biological treatment. Proteobacteria and Bacteroidetes were the most abundant in aerobic and anaerobic conditions, respectively [67, 68]. As reported by Rimkus et al. [47], addition of three types of carbon sources (faba bean straw, wheat straw, and wood-chip pellets) to the raw SS resulted in considerable changes in microbial community structure after 16 days of aerobic incubation. In particular, abundance of Firmicutes increased from 5% in the raw SS to 35–50% in the treated samples. In turn, abundance of Proteobacteria decreased from 62% in the raw SS to 32–45% in the treated samples. Yet, the SS incubation without C amendment resulted in a remarkable increase in virus abundance (i.e., 0.34% reads) [47]. The relative abundance of
When SS is applied to soil, it causes changes in the structure and functioning of the agroecosystem. The most sensitive component is the soil microbiota, which can undergo both stimulatory and inhibitory changes in the activity and structure. These changes are greatly dependent on soil characteristics and SS application rate.
The microcosm experiment with SS-amended sandy soil (25.71 g SS/kg dry soil) after 119 days has revealed significant changes in prokaryotic community composition at the phylum level, as compared to the non-amended control [48]. Specifically, in SS-amended soil, the relative abundance of Firmicutes reduced from 58.6% at Day 0 to 18.7% at Day 119, while Proteobacteria increased from 15.5% to 36.4%, respectively [69]. In the control soil, these two respective phyla did not change considerably for 119 days. The relative abundance of Actinobacteria in SS-amended soil has increased from 3.1% to 13.2%, while in the control soil decreased from 27.6% to 19.4% [69].
The use of sludge as a soil amendment has been shown to increase the activity of soil enzymes, for example, arylsulfatase, acid phosphatase, and alkaline phosphatase. Basal respiration and the fluorescein diacetate hydrolysis activity increased with increasing the dose of SS [70]. Changes in urease activity by soil microorganisms can be discussed in two aspects. First, urease activity reflects the activity of microorganisms involved in the nitrogen cycle in soil [71]. Another aspect is related to the global loss of nitrogen (up to 70%) due to urease activity if urea is applied as a fertilizer. Therefore, urease inhibition is one of the strategies worldwide to maintain soil fertility [72]. In our experiments, combination of dry SS with nitrogen-containing fertilizer resulted in inhibition of urease activity in loamy soil during the vegetation experiment with maize [73].
The addition of SS-derived organics to soil increases the Cmic/Ctotal and Nmic/Ntotal ratios in the soil. At the same time, application of SS containing heavy metals, according to Fließbach et al. [8] and Chander and Brookes [74], Cmic/Ctotal ratio decreases to 32% and 50%, respectively. This effect can be developed greater in sandy soil than in clayey soils [75].
In the early nineteenth century, the total coliforms, fecal coliforms, and fecal streptococci were considered as typical indicator bacteria. Later it was shown that these pathogens are not a major concern in solid waste landfills or leachate [62, 76]. Nowadays, different types of bacteria (fecal coliforms and
Soil amendment with SS is useful for enhancing crop production, as well as the accumulation of nutrients and organic matter in the soil. However, the accumulation of humic substances (HS) in soil and plant tissues must be regularly observed in case the SS is continuously used [14]. The SS can be used as fertilizers also after pyrolysis [77]. Both sole application of SS and their respective biochars provided enough P for the plants to achieve biomass higher than conventional P-fertilizer [77].
The effect of SS on plant growth differs depending on the SS application method, that is, at the soil surface “mulching” or mixed homogeneously with soil. The application of SS on the surface has some advantages, that is, water evaporation is limited by forming a physical barrier that allows soil moisture to be retained longer. Due to those, the biological and chemical processes of organic matter transformation intensified [78]. For example, the best yield of wheat (
Importantly, a direct application of SS on agricultural soils is not recommended. It was shown that the hygienically treated (by liming) SS inhibited the growth of white mustard (
Our experiments showed that the use of SS affects the germination and development of seedlings. Concentrations exceeding 7 g kg−1 inhibited the germination of cucumber seeds and resulted in necrotizing primary roots. In the study with air-dried SS mixed with agricultural sandy loam soil at rates of 0 (control), 10, 20, 30, 40, and 50 g kg−1 (equal to 0, 30, 60, 90, 120, and 150 t ha−1), seed germination of broad beans (
Our recent study demonstrated a positive effect of SS on maize growth and soil microbiological activity, when SS is applied in combination with mineral fertilizers [73]. Additional experiments have been performed also with cucumbers and leaf mustard. The SS preparation alone did not provide the plants with mineral nutrients in appropriate values, while the combination of SS preparation with nitrogen-containing fertilizers significantly improved the plant growth and promoted plant development [73] (Figure 6). This may have a long-term favorable effect on plant mineral nutrition. Our data also showed that different plants respond to the SS differently. A species-specific effect, in that case, can be explained by (i) different sensitivity of plants to the compounds in SS preparations; (ii) demand for mineral elements at the early stages of ontogenesis due to slow release of nutrients from SS; (iii) insufficient maturing and the presence of growth inhibitors in SS.
The effect of SSP on the growth of plants: A—cucumbers, B—leaf mustard, C–E—maize. Label color: pink—SSP + NPK, orange—NPK, blue—SSP + PK, green—SSP, yellow—vermicompost, white—soil without fertilizers. SSP—sewage sludge preparation; PK—phosphorus and potassium-containing fertilizer; NPK—nitrogen, phosphorus, and potassium-containing fertilizer. Controls—loamy soil without additional fertilizer, soil mixed with mineral fertilizer (Kristalon 18:18:18). Period of vegetation experiment A—18 days, B—47 days, C—33 days, E—46 days, and D—62 days. The application rate of SSP is 17.3 g L−1 in a loamy soil. Methods are according to Dubova et al. [
Sludge production globally in 2017 was 45 MT by dry matter, and now it is increasing annually due to urbanization and population growth [34, 93]. In this respect, the environmental impact of SS in the case of landfill disposal, agricultural use, or other applications is of great importance. Particularly, the contribution of different processes of SS treatment for agricultural use is recently studied by [59]. Energy consumption for SS treatment contributed mostly to global warming (>50%), while SS transportation to agricultural areas affected terrestrial and freshwater ecotoxicity, as well as ozone formation—terrestrial ecosystems (Figure 7A
Environmental life-cycle assessment of the sewage treatment plant: contribution of different activities. A—energy consumption; B—transport of sludge to agricultural areas; C—agricultural areas sludge disposal. By Do Amaral et al. [
Biogeochemical emissions from SS handling and spreading on land are expected to be minimized in the future by efficient utilization of nutrients and other resources derived from SS, according to the principles of a circular economy [95, 96]. The processed land-applied SS can emit volatile chemicals and gases that may act alone or in combination with one another to produce the kinds of symptoms [63].
The composition of the sludge and the concentration of pollutants in it predetermine the possibilities of its use. The presence of heavy metals, organic pollutants, and/or pathogens are the main issues associated with the reuse of SS or biosolids extracted from it. According to Manzetti and van der Spoel [97], the following aspects can be reported—(a) raising of the levels of persistent toxins in soil, vegetation, and wildlife, (b) potentially slow and long-termed biodiversity reduction through the fertilizing nutrient pollution operating on the vegetation, (c) greenhouse gas emissions, and (d) the release of odorous compounds. Groundwater contamination from biosolids with pathogenic microorganisms is one of the greatest problems worldwide, due to the lack of adequate and equitable sanitation of SS [98]. Chemical contaminants in processed SS may potentially interact with microbial pathogens, thus, causing or facilitating the disease process via allergic and nonallergic mechanisms, as well as microbial byproducts [63]. Furthermore, endotoxins and exotoxins, which are produced by most bacteria in SS and retain their toxicity at extremely high dilutions, can cause severe illness or death. Endotoxins are heat stable even upon autoclaving, while can be inactivated with dry heat at temperature above 200°C for 1 h [79, 99, 100]. A high microbial diversity of SS leads to the horizontal gene transfer and proliferation of antimicrobial resistance (AMR) [101]. The virus persistence in SS is dependent on the physicochemical and biological properties. For example, enveloped viruses survive for 6–7 days in SS [102], while SARS-CoV-2 might persist on the surfaces up to 72 h [69]. Coronavirus can persist in domestic and hospital SS also for a longer period of time at lower temperatures (4°C) [62, 103].
Long-term accumulation of toxic elements in soil and their uptake by plants is currently the biggest concern in terms of direct SS land application. The bioavailability of heavy metals in the soil is closely related to the value of the soil exchange reaction (soil pH measured in KCl or CaCl2 form), as well as to the sorption properties of the soil, which change with the addition of SS. According to published data, the availability of heavy metals in soils decreases in the order (Zn + Cd) > (Ni + Cu) > (Pb + Cr). However, in connection with physicochemical processes, the accumulation of heavy metals may occur over time, so it is necessary to monitor their concentration for a long time after the application of sludge [104]. When sludge is incorporated into the soil, the heavy metals in it bind to organic matter and clay particles, which usually accumulate in the soil [8, 105].
In Latvia, no more than 14 t ha−1 of dry matter may be incorporated at a time with sludge or compost. This corresponds to 55 t ha−1 of naturally moist sludge with a dry matter content of about 25% [106]. For 18 years, the concentration of heavy metals in Jelgava SS has significantly decreased. Similar trends have been observed in other treatment plants and this shows that heavy metals are no longer the most important limiting factor for the use of SS.
Wastewater can transport plastics from many different sources, such as fibers from washing machines, personal care products, and facial scrubs. WWTP efficiently removes the microplastics (MPs) from the wastewater, essentially trapping the particles in the sludge [107, 108]. Studies of Peterson [76] showed that 9 years of repeated sludge application led to the accumulation of MPs in the soil. According to various studies, MPs pose various negative effects on soil ecosystems, such as affecting soil fertility, soil organisms’ fitness, soil texture, and decreasing crop yield [109, 110].
Pignattelli et al. [111] highlighted the toxicity caused by small MPs (PP, PE, and PVC) on the growth of garden cress (
Domestic SS is a major source of pharmaceuticals, drugs, and antibiotic resistance genes, so it is important to ensure its biodegradation during sludge treatment. Drugs can remain in the sludge even after stabilization (dewatering), due to their high sorption capacity [113]. Ivanová et al. [114] discovered more than 100 types of drugs and their metabolites in SS. The amount and type of antibiotics in wastewater affect also the composition of bacteria [115].
Pharmaceutical substances are subject to thermal decomposition over a wide temperature range; therefore, it is possible to expect a reduction in the content or their complete removal during thermal processes [116]. Szabová et al. [117] achieved almost 100% drug removal in the sludge by heat treatment at 250°C and incineration at 550°C. Furthermore, pyrolysis at 350–500°C is able to decrease the concentration of MPs in sludge by more than 99% [118].
The efficient use of waste-derived fertilizers in agriculture needs more empirical knowledge on markets with further research focused on variability, interactivity, and uncertainty. The site-specific factors (e.g., applied technology, quantity, and the origin of raw wastewater differed by the composition of macro- and microelements and risk compounds, soil types, and crops) make each SS unique, hence this specificity must be considered to predict the outcome of SS treatment. New efficient technologies for onsite sludge disinfection are necessary and urgent. Interdisciplinary activities on the safe use of SS upon treatment and application need to be thoroughly analyzed and developed, for example, planning, servicing, diagnosing, storing, and others. Furthermore, macroeconomic factors can considerably influence technology stocks. Soaring gas prices directly affected the production of synthetic fertilizers costs. High prices as well as the disruption of transport and production logistics lead to a real threat of a dramatic reduction in supply on the mineral fertilizers market. Combined with higher prices, an increase in demand for less volatile organic fertilizers can be expected.
Summarizing our experimental data on optimization of SS treatment and its application in agriculture, as well as recent findings of other authors in this field, the following conclusions were drawn:
The technology, which was newly developed by Earth Revival Ltd., offers an innovative and comprehensive solution to the problem of SS disposal and soil degradation, which includes aspects of agriculture, healthcare, epidemics, ecology, economics, and the social sphere. Costs can be recuperated through sludge treatment service fees and fertilizer sales.
The infrared heating system, used for SS disinfection, has shown consistently successful results. For the material with a humidity of 80%, it took 15 min, considering the heating time of the layer to 95°C, which is below the temperature of the organic matter decomposition. Research and experiments related to the neutralization of the spore-forming bacteria are planned to be realized in the next stage of the project.
The technology (SS transportation system, maturation process) can be used for fast, safe, and efficient SS processing into organic fertilizer. It also combines well with the anaerobic digestion process as it can complete the digestive sludge transformation to a huge quality fertilizer.
Sewage sludge can replace mineral fertilizers in crop production. Attention should be paid to the amount and ratio of mineral elements available to the plant during plant growth. Sewage sludge may not fully provide plants with potassium and phosphorus. Sewage sludge is recommended for plants with a longer vegetation period due to the slow release of nutrients. A phytotoxic effect may occur during seed germination.
This research is being conducted based on agreement with SIA “ETKC” (Centre of Competence for Energy and Transportation) within the framework of project Nr.1.2.1.1/18/A/001 co-funded by the European Regional Development Fund.
The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
IntechOpen - where academia and industry create content with global impact
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\n\nDr Alex Lazinica
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Taiar",coverURL:"https://cdn.intechopen.com/books/images_new/7543.jpg",editedByType:"Edited by",editors:[{id:"157376",title:"Prof.",name:"Mario",middleName:null,surname:"Bernardo-Filho",slug:"mario-bernardo-filho",fullName:"Mario Bernardo-Filho"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"6772",title:"Occupational Therapy",subtitle:"Therapeutic and Creative Use of Activity",isOpenForSubmission:!1,hash:"0f6de90c02282919494d6254e473defe",slug:"occupational-therapy-therapeutic-and-creative-use-of-activity",bookSignature:"Meral Huri",coverURL:"https://cdn.intechopen.com/books/images_new/6772.jpg",editedByType:"Edited by",editors:[{id:"171525",title:"Dr.",name:"Meral",middleName:null,surname:"Huri",slug:"meral-huri",fullName:"Meral Huri"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"5711",title:"Occupational Therapy",subtitle:"Occupation Focused Holistic Practice in Rehabilitation",isOpenForSubmission:!1,hash:"38180e287b6cb09b8002b7ab485de2c2",slug:"occupational-therapy-occupation-focused-holistic-practice-in-rehabilitation",bookSignature:"Meral Huri",coverURL:"https://cdn.intechopen.com/books/images_new/5711.jpg",editedByType:"Edited by",editors:[{id:"171525",title:"Dr.",name:"Meral",middleName:null,surname:"Huri",slug:"meral-huri",fullName:"Meral Huri"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],booksByTopicTotal:3,seriesByTopicCollection:[],seriesByTopicTotal:0,mostCitedChapters:[{id:"55163",doi:"10.5772/intechopen.68799",title:"Virtual Reality and Occupational Therapy",slug:"virtual-reality-and-occupational-therapy",totalDownloads:2642,totalCrossrefCites:4,totalDimensionsCites:6,abstract:"Virtual reality is three dimensional, interactive and fun way in rehabilitation. Its first known use in rehabilitation published by Max North named as “Virtual Environments and Psychological Disorders” (1994). Virtual reality uses special programmed computers, visual devices and artificial environments for the clients’ rehabilitation. Throughout technological improvements, virtual reality devices changed from therapeutic gloves to augmented reality environments. Virtual reality was being used in different rehabilitation professions such as occupational therapy, physical therapy, psychology and so on. In spite of common virtual reality approach of different professions, each profession aims different outcomes in rehabilitation. Virtual reality in occupational therapy generally focuses on hand and upper extremity functioning, cognitive rehabilitation, mental disorders, etc. Positive effects of virtual reality were mentioned in different studies, which are higher motivation than non‐simulated environments, active participation of the participants, supporting motor learning, fun environment and risk‐free environment. Additionally, virtual reality was told to be used as assessment. This chapter will focus on usage of virtual reality in occupational therapy, history and recent developments, types of virtual reality technologic equipment, pros and cons, usage for pediatric, adult and geriatric people and recent research and articles.",book:{id:"5711",slug:"occupational-therapy-occupation-focused-holistic-practice-in-rehabilitation",title:"Occupational Therapy",fullTitle:"Occupational Therapy - Occupation Focused Holistic Practice in Rehabilitation"},signatures:"Orkun Tahir Aran, Sedef Şahin, Berkan Torpil, Tarık Demirok and\nHülya Kayıhan",authors:[{id:"172938",title:"Prof.",name:"Hulya",middleName:null,surname:"Kayihan",slug:"hulya-kayihan",fullName:"Hulya Kayihan"},{id:"183079",title:"Ph.D.",name:"Sedef",middleName:null,surname:"Şahin",slug:"sedef-sahin",fullName:"Sedef Şahin"},{id:"196848",title:"M.Sc.",name:"Orkun Tahir",middleName:null,surname:"Aran",slug:"orkun-tahir-aran",fullName:"Orkun Tahir Aran"},{id:"197159",title:"Mr.",name:"Tarık",middleName:null,surname:"Demirok",slug:"tarik-demirok",fullName:"Tarık Demirok"},{id:"197312",title:"M.Sc.",name:"Berkan",middleName:null,surname:"Torpil",slug:"berkan-torpil",fullName:"Berkan Torpil"}]},{id:"61806",doi:"10.5772/intechopen.78312",title:"Executive Functions and Neurology in Children and Adolescents",slug:"executive-functions-and-neurology-in-children-and-adolescents",totalDownloads:1759,totalCrossrefCites:3,totalDimensionsCites:5,abstract:"This chapter discusses the theoretical and methodological issues of creating a developmental perspective on executive function (EF) in childhood and adolescence. Focusing on school periods, this section outlines the development of the basic components of EF—inhibition, working memory, and attention. Cognitive and neurophysiological evaluations show that despite the emergence of EF in the first few years of life, it continues to grow significantly in childhood and adolescence. The components vary slightly according to their developmental sequence. The chapter links findings to long-standing developmental issues (i.e. developmental sequences and processes) and suggests the necessary research to establish a developmental framework covering early childhood throughout adolescence.",book:{id:"6772",slug:"occupational-therapy-therapeutic-and-creative-use-of-activity",title:"Occupational Therapy",fullTitle:"Occupational Therapy - Therapeutic and Creative Use of Activity"},signatures:"Gokcen Akyurek",authors:[{id:"197265",title:"Dr.",name:"Gokcen",middleName:null,surname:"Akyurek",slug:"gokcen-akyurek",fullName:"Gokcen Akyurek"}]},{id:"55024",doi:"10.5772/intechopen.68463",title:"Occupational Therapy in Oncology and Palliative Care",slug:"occupational-therapy-in-oncology-and-palliative-care",totalDownloads:2699,totalCrossrefCites:1,totalDimensionsCites:4,abstract:"Cancer is a chronic disease that may occur in both children and adults. Occupational therapy focuses on the activity limitations and participation problems in their life. Oncology rehabilitation involves in helping an individual with cancer to regain maximum physical, psychological, cognitive, social, and vocational functioning with the limits up to disease and its treatments in an interdisciplinary team concept. These treatment options are associated with the risk of some side effects, including fatigue, pain, cognitive problems, decrease in bone density and muscle endurance, weight loss, and stress- or anxiety-related psychosocial problems. Occupational therapy approaches are a holistic view in a client center and use training in activities of daily living, assistive technology, education of energy conservation techniques, and management of treatment-related problems, such as pain, fatigue, and nausea. In palliative and hospice care, occupational therapists support clients with cancer by minimizing the secondary symptoms related to cancer and its treatments. At the end of life, occupational therapy offers to identify the roles and activities that are meaningful and purposeful to the client with cancer and try to determine the barriers that limit their performance. Clients with cancer who have childhood cancer or adult cancer can face problems about body structure and functions, activity, and participation, which may limit their participation to their daily life.",book:{id:"5711",slug:"occupational-therapy-occupation-focused-holistic-practice-in-rehabilitation",title:"Occupational Therapy",fullTitle:"Occupational Therapy - Occupation Focused Holistic Practice in Rehabilitation"},signatures:"Sedef Şahin, Semin Akel and Meral Zarif",authors:[{id:"183079",title:"Ph.D.",name:"Sedef",middleName:null,surname:"Şahin",slug:"sedef-sahin",fullName:"Sedef Şahin"},{id:"183078",title:"Dr.",name:"Burcu Semin",middleName:null,surname:"Akel",slug:"burcu-semin-akel",fullName:"Burcu Semin Akel"},{id:"198859",title:"Dr.",name:"Meral",middleName:null,surname:"Zarif",slug:"meral-zarif",fullName:"Meral Zarif"}]},{id:"56049",doi:"10.5772/intechopen.69101",title:"Measurement of Participation: The Role Checklist Version 3: Satisfaction and Performance",slug:"measurement-of-participation-the-role-checklist-version-3-satisfaction-and-performance",totalDownloads:2823,totalCrossrefCites:3,totalDimensionsCites:4,abstract:"Participation in society is an area of interest to both clinicians and population researchers. Measurement of participation is therefore important, yet differences in definition, in terms of both content and scope, have made general agreement on one instrument tool elusive. What is recognized is the need for a theoretically based tool that captures both the insider and the outsider perspective. The outsider perspective, inclusive of the generally held views of a society, supports the utility for aggregating population data, whereas the insider perspective provides the internally held views of an individual needed for client-centered treatment planning. The Role Checklist Version 3 modifies one of the most commonly used assessment tools in occupational therapy practice, has good preliminary psychometric properties, and is theoretically consistent with both the ICF and the Model of Human Occupation. The Model of Human Occupation is the most widely used theoretical model in occupational therapy. This chapter provides an overview of the theoretical development, empirical testing, and implications for use of this participation measure by occupational therapists along with implications for population researchers.",book:{id:"5711",slug:"occupational-therapy-occupation-focused-holistic-practice-in-rehabilitation",title:"Occupational Therapy",fullTitle:"Occupational Therapy - Occupation Focused Holistic Practice in Rehabilitation"},signatures:"Patricia J. Scott, Kelsey McKinney, Jeff Perron, Emily Ruff and Jessica\nSmiley",authors:[{id:"195495",title:"Dr.",name:"Patricia J",middleName:null,surname:"Scott",slug:"patricia-j-scott",fullName:"Patricia J Scott"},{id:"208801",title:"Dr.",name:"Kelsey G.",middleName:null,surname:"McKinney",slug:"kelsey-g.-mckinney",fullName:"Kelsey G. McKinney"},{id:"208802",title:"Mr.",name:"Jeffrey M.",middleName:null,surname:"Perron",slug:"jeffrey-m.-perron",fullName:"Jeffrey M. Perron"},{id:"208803",title:"Dr.",name:"Emily G.",middleName:null,surname:"Ruff",slug:"emily-g.-ruff",fullName:"Emily G. Ruff"},{id:"208804",title:"Dr.",name:"Jessica L.",middleName:null,surname:"Smiley",slug:"jessica-l.-smiley",fullName:"Jessica L. Smiley"}]},{id:"55018",doi:"10.5772/intechopen.68315",title:"Psychomotor Therapy for Patients with Severe Mental Health Disorders",slug:"psychomotor-therapy-for-patients-with-severe-mental-health-disorders",totalDownloads:2274,totalCrossrefCites:3,totalDimensionsCites:3,abstract:"Psychomotor therapy is defined as a method of treatment based on a holistic view of the human being that is derived from the unity of body and mind. Assessments (observation and/or evaluation) are essential to achieving concrete psychosocial objectives methodically. Psychomotor therapy uses movement, body awareness and a wide range of movement activities to optimize movement behaviour as well as the cognitive, affective and relational aspects of psychomotor functioning (i.e. the relationships between physical movements and cognitive and social-affective aspects). Consequently, the approach to this type of therapy integrates the physical, cognitive and emotional aspects of functioning in relation to the capacity of being and acting in a psychosocial context in order to achieve clearly defined goals in consultation with the patients. Psychomotor therapy framework consists of three different approaches: a health-related approach, a psychosocial approach and a psychotherapeutic approach, which can be embedded in several psychotherapeutic approaches. Through the implementation of both systematically planned evaluations and individually targeted interventions in group, the psychomotor therapist strives to broaden the general action competences and specific skills and to stimulate a positive self-image and personal well-being in balanced social relationships. Today, there is sufficient evidence that psychomotor therapy has a major contribution to both well-being and mental health of patients with severe psychiatric problems. In Flemish psychiatric hospitals, psychomotor therapy is imbedded in different treatment programmes. In this chapter, the theory behind this approach and some practical examples will be provided.",book:{id:"5711",slug:"occupational-therapy-occupation-focused-holistic-practice-in-rehabilitation",title:"Occupational Therapy",fullTitle:"Occupational Therapy - Occupation Focused Holistic Practice in Rehabilitation"},signatures:"Michel Probst",authors:[{id:"196227",title:"Prof.",name:"Michel",middleName:null,surname:"Probst",slug:"michel-probst",fullName:"Michel Probst"}]}],mostDownloadedChaptersLast30Days:[{id:"55080",title:"Life Skills in Occupational Therapy",slug:"life-skills-in-occupational-therapy",totalDownloads:6076,totalCrossrefCites:4,totalDimensionsCites:1,abstract:"Occupational therapy is a health profession that uses the purposeful activities to achieve multiple and complex rehabilitation aims. The main goals of the occupational therapy are to support the reintegration of individuals in daily living skills as well as to increase their independence and autonomy. Interventions of occupational therapists have primarily focused on self-care, productivity, and leisure time activities. Since the life skills includes a wide range of abilities that enable a person to perform personal care and more complicated tasks such as traveling, shopping, community participation etc., occupational therapists provide life skills training programs to meet the needs of the clients. This chapter aims to contribute to the current understanding and practices of life skills from an occupational therapy perspective. The chapter starts with a brief discussion of the importance of life skills in occupational therapy. After this introduction, the first part takes a look at the definition of life skills and identifies core components of life skills. The second part describes assessment and interventions of life skills. The third one gives an overview about school life skills programs for children and adolescents. Finally, the last part explains some life skills programs in people with disadvantages.",book:{id:"5711",slug:"occupational-therapy-occupation-focused-holistic-practice-in-rehabilitation",title:"Occupational Therapy",fullTitle:"Occupational Therapy - Occupation Focused Holistic Practice in Rehabilitation"},signatures:"Hatice Abaoğlu, Özge Buket Cesim, Sinem Kars and Zeynep Çelik",authors:[{id:"197551",title:"Dr.",name:"Hatice",middleName:null,surname:"Abaoğlu",slug:"hatice-abaoglu",fullName:"Hatice Abaoğlu"},{id:"205199",title:"Dr.",name:"Sinem",middleName:null,surname:"Kars",slug:"sinem-kars",fullName:"Sinem Kars"},{id:"205200",title:"Dr.",name:"Zeynep",middleName:null,surname:"Celik",slug:"zeynep-celik",fullName:"Zeynep Celik"},{id:"205203",title:"Ms.",name:"Özge Buket",middleName:null,surname:"Cesim",slug:"ozge-buket-cesim",fullName:"Özge Buket Cesim"}]},{id:"62493",title:"Occupational Therapy in Forensic Settings",slug:"occupational-therapy-in-forensic-settings",totalDownloads:2543,totalCrossrefCites:2,totalDimensionsCites:2,abstract:"It is necessary for a person to comply with the expectations of society and the rules of law to which these expectations are secured. Offenders turn back to the community after the penalty was executed by isolating from society and some occupations. An occupational imbalance is seen in the individuals, during this penalty period and afterward, because of limited occupational participation. As an occupational being, this affects their physical, mental and psychological well-being. Imprisonment is an important practice in criminal law to punish criminals. This may be necessary for the protection of society from criminals, but successful integration into a community after exiting the prison is the most important factor in preventing recidivism. Occupational therapy focuses on health and well-being by using meaningful and purposeful occupations. Occupation involves any activity that people perform or participate in, such as giving care to themselves or others, working, learning, playing games, and interacting with others. From this perspective, the role of occupational therapists in forensic settings is to determine the abilities of these individuals to congregate their deprived freedoms and use them to train them for an independent and autonomous life; to provide a professional orientation, career counseling, and self-esteem; to gain some habits for physical, spiritual and moral life and to reinforce.",book:{id:"6772",slug:"occupational-therapy-therapeutic-and-creative-use-of-activity",title:"Occupational Therapy",fullTitle:"Occupational Therapy - Therapeutic and Creative Use of Activity"},signatures:"Esma Ozkan, Sümeyye Belhan, Mahmut Yaran and Meral Zarif",authors:null},{id:"70122",title:"Parkinson’s Disease Rehabilitation: Effectiveness Approaches and New Perspectives",slug:"parkinson-s-disease-rehabilitation-effectiveness-approaches-and-new-perspectives",totalDownloads:2083,totalCrossrefCites:2,totalDimensionsCites:3,abstract:"Parkinson’s disease has been considered one of the most important and common neurodegenerative diseases in the world. Its motor and nonmotor signs determine a huge functional loss, leading the individuals to lose their independence. Although the treatment requires a pharmacological approach, physical therapy has confirmed its importance in this process. Today, neurorehabilitation is indispensable to increase many of the cardinal signs of the disease. Using traditional or technological approaches, physical therapy has reached good results in improving motor and nonmotor functions, as well as the quality of life of Parkinsonians. However, it is important to develop and to fortify the physical therapy approach so that we can provide stronger evidence about our practice.",book:{id:"7543",slug:"physical-therapy-effectiveness",title:"Physical Therapy Effectiveness",fullTitle:"Physical Therapy Effectiveness"},signatures:"Luciana Auxiliadora de Paula Vasconcelos",authors:[{id:"98546",title:"Dr.",name:"Luciana Auxiliadora",middleName:null,surname:"De Paula Vasconcelos",slug:"luciana-auxiliadora-de-paula-vasconcelos",fullName:"Luciana Auxiliadora De Paula Vasconcelos"}]},{id:"62210",title:"Occupational Therapy’s Role in the Treatment of Children with Autism Spectrum Disorders",slug:"occupational-therapy-s-role-in-the-treatment-of-children-with-autism-spectrum-disorders",totalDownloads:2756,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"Occupational therapists (OT) offer a wide range of therapies for individuals with ASD on the basis of specific deficits and difficulties. This chapter explores the role that OT plays, and the expertise, in relation to the interdisciplinary team. In addition, it discusses and presents empirical support for several therapeutic approaches commonly used by OTs working with individuals with ASD.",book:{id:"6772",slug:"occupational-therapy-therapeutic-and-creative-use-of-activity",title:"Occupational Therapy",fullTitle:"Occupational Therapy - Therapeutic and Creative Use of Activity"},signatures:"Bryan M. Gee, Amy Nwora and Theodore W. Peterson",authors:null},{id:"55049",title:"Community Participation in People with Disabilities",slug:"community-participation-in-people-with-disabilities",totalDownloads:2436,totalCrossrefCites:2,totalDimensionsCites:2,abstract:"Despite the fact that participation is an important building and a valuable target, the conceptualization, identification and measurement methods vary widely. This chapter tried to gain an insider’s perspective from the obstacles that summarize what meaning participation means, how to characterize it, and what prevents and supports participation. Participation is seen as a right and a responsibility attributed to and attributed to both the person and the community. Participation does not take place in a vacuum; the environment dynamically influences participation. 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Currently, he is a Professor at Xiangya Hospital of Central South University in China, Fellow of Royal Society of Medicine (FRSM), the European EPMA National Representative in China, Regular Member of American Association for the Advancement of Science (AAAS), European Cooperation of Science and Technology (e-COST) grant evaluator, Associate Editors of BMC Genomics, BMC Medical Genomics, EPMA Journal, and Frontiers in Endocrinology, Executive Editor-in-Chief of Med One. He has\npublished 116 peer-reviewed research articles, 16 book chapters, 2 books, and 2 US patents. His current main research interest focuses on the studies of cancer proteomics and biomarkers, and the use of modern omics techniques and systems biology for PPPM in cancer, and on the development and use of 2DE-LC/MS for the large-scale study of human proteoforms.",institutionString:null,institution:{name:"Xiangya Hospital Central South University",country:{name:"China"}}},{id:"40482",title:null,name:"Rizwan",middleName:null,surname:"Ahmad",slug:"rizwan-ahmad",fullName:"Rizwan Ahmad",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/40482/images/system/40482.jpeg",biography:"Dr. Rizwan Ahmad is a University Professor and Coordinator, Quality and Development, College of Medicine, Imam Abdulrahman bin Faisal University, Saudi Arabia. Previously, he was Associate Professor of Human Function, Oman Medical College, Oman, and SBS University, Dehradun. Dr. Ahmad completed his education at Aligarh Muslim University, Aligarh. He has published several articles in peer-reviewed journals, chapters, and edited books. His area of specialization is free radical biochemistry and autoimmune diseases.",institutionString:"Imam Abdulrahman Bin Faisal University",institution:{name:"Imam Abdulrahman Bin Faisal University",country:{name:"Saudi Arabia"}}},{id:"41865",title:"Prof.",name:"Farid A.",middleName:null,surname:"Badria",slug:"farid-a.-badria",fullName:"Farid A. Badria",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/41865/images/system/41865.jpg",biography:"Farid A. Badria, Ph.D., is the recipient of several awards, including The World Academy of Sciences (TWAS) Prize for Public Understanding of Science; the World Intellectual Property Organization (WIPO) Gold Medal for best invention; Outstanding Arab Scholar, Kuwait; and the Khwarizmi International Award, Iran. He has 250 publications, 12 books, 20 patents, and several marketed pharmaceutical products to his credit. He continues to lead research projects on developing new therapies for liver, skin disorders, and cancer. Dr. Badria was listed among the world’s top 2% of scientists in medicinal and biomolecular chemistry in 2019 and 2020. He is a member of the Arab Development Fund, Kuwait; International Cell Research Organization–United Nations Educational, Scientific and Cultural Organization (ICRO–UNESCO), Chile; and UNESCO Biotechnology France",institutionString:"Mansoura University",institution:{name:"Mansoura University",country:{name:"Egypt"}}},{id:"329385",title:"Dr.",name:"Rajesh K.",middleName:"Kumar",surname:"Singh",slug:"rajesh-k.-singh",fullName:"Rajesh K. Singh",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/329385/images/system/329385.png",biography:"Dr. Singh received a BPharm (2003) and MPharm (2005) from Panjab University, Chandigarh, India, and a Ph.D. (2013) from Punjab Technical University (PTU), Jalandhar, India. He has more than sixteen years of teaching experience and has supervised numerous postgraduate and Ph.D. students. He has to his credit more than seventy papers in SCI- and SCOPUS-indexed journals, fifty-five conference proceedings, four books, six Best Paper Awards, and five projects from different government agencies. He is currently an editorial board member of eight international journals and a reviewer for more than fifty scientific journals. He received Top Reviewer and Excellent Peer Reviewer Awards from Publons in 2016 and 2017, respectively. He is also on the panel of The International Reviewer for reviewing research proposals for grants from the Royal Society. He also serves as a Publons Academy mentor and Bentham brand ambassador.",institutionString:"Punjab Technical University",institution:{name:"Punjab Technical University",country:{name:"India"}}},{id:"142388",title:"Dr.",name:"Thiago",middleName:"Gomes",surname:"Gomes Heck",slug:"thiago-gomes-heck",fullName:"Thiago Gomes Heck",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/142388/images/7259_n.jpg",biography:null,institutionString:null,institution:{name:"Universidade Regional do Noroeste do Estado do Rio Grande do Sul",country:{name:"Brazil"}}},{id:"336273",title:"Assistant Prof.",name:"Janja",middleName:null,surname:"Zupan",slug:"janja-zupan",fullName:"Janja Zupan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/336273/images/14853_n.jpeg",biography:"Janja Zupan graduated in 2005 at the Department of Clinical Biochemistry (superviser prof. dr. Janja Marc) in the field of genetics of osteoporosis. Since November 2009 she is working as a Teaching Assistant at the Faculty of Pharmacy, Department of Clinical Biochemistry. In 2011 she completed part of her research and PhD work at Institute of Genetics and Molecular Medicine, University of Edinburgh. She finished her PhD entitled The influence of the proinflammatory cytokines on the RANK/RANKL/OPG in bone tissue of osteoporotic and osteoarthritic patients in 2012. From 2014-2016 she worked at the Institute of Biomedical Sciences, University of Aberdeen as a postdoctoral research fellow on UK Arthritis research project where she gained knowledge in mesenchymal stem cells and regenerative medicine. She returned back to University of Ljubljana, Faculty of Pharmacy in 2016. She is currently leading project entitled Mesenchymal stem cells-the keepers of tissue endogenous regenerative capacity facing up to aging of the musculoskeletal system funded by Slovenian Research Agency.",institutionString:null,institution:{name:"University of Ljubljana",country:{name:"Slovenia"}}},{id:"357453",title:"Dr.",name:"Radheshyam",middleName:null,surname:"Maurya",slug:"radheshyam-maurya",fullName:"Radheshyam Maurya",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/357453/images/16535_n.jpg",biography:null,institutionString:null,institution:{name:"University of Hyderabad",country:{name:"India"}}},{id:"418340",title:"Dr.",name:"Jyotirmoi",middleName:null,surname:"Aich",slug:"jyotirmoi-aich",fullName:"Jyotirmoi Aich",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000038Ugi5QAC/Profile_Picture_2022-04-15T07:48:28.png",biography:"Biotechnologist with 15 years of research including 6 years of teaching experience. Demonstrated record of scientific achievements through consistent publication record (H index = 13, with 874 citations) in high impact journals such as Nature Communications, Oncotarget, Annals of Oncology, PNAS, and AJRCCM, etc. Strong research professional with a post-doctorate from ACTREC where I gained experimental oncology experience in clinical settings and a doctorate from IGIB where I gained expertise in asthma pathophysiology. A well-trained biotechnologist with diverse experience on the bench across different research themes ranging from asthma to cancer and other infectious diseases. An individual with a strong commitment and innovative mindset. Have the ability to work on diverse projects such as regenerative and molecular medicine with an overall mindset of improving healthcare.",institutionString:"DY Patil Deemed to Be University",institution:null},{id:"349288",title:"Prof.",name:"Soumya",middleName:null,surname:"Basu",slug:"soumya-basu",fullName:"Soumya Basu",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000035QxIDQA0/Profile_Picture_2022-04-15T07:47:01.jpg",biography:"Soumya Basu, Ph.D., is currently working as an Associate Professor at Dr. D. Y. Patil Biotechnology and Bioinformatics Institute, Dr. D. Y. Patil Vidyapeeth, Pune, Maharashtra, India. With 16+ years of trans-disciplinary research experience in Drug Design, development, and pre-clinical validation; 20+ research article publications in journals of repute, 9+ years of teaching experience, trained with cross-disciplinary education, Dr. Basu is a life-long learner and always thrives for new challenges.\r\nHer research area is the design and synthesis of small molecule partial agonists of PPAR-γ in lung cancer. She is also using artificial intelligence and deep learning methods to understand the exosomal miRNA’s role in cancer metastasis. Dr. Basu is the recipient of many awards including the Early Career Research Award from the Department of Science and Technology, Govt. of India. She is a reviewer of many journals like Molecular Biology Reports, Frontiers in Oncology, RSC Advances, PLOS ONE, Journal of Biomolecular Structure & Dynamics, Journal of Molecular Graphics and Modelling, etc. She has edited and authored/co-authored 21 journal papers, 3 book chapters, and 15 abstracts. She is a Board of Studies member at her university. She is a life member of 'The Cytometry Society”-in India and 'All India Cell Biology Society”- in India.",institutionString:"Dr. D.Y. Patil Vidyapeeth, Pune",institution:{name:"Dr. D.Y. Patil Vidyapeeth, Pune",country:{name:"India"}}},{id:"354817",title:"Dr.",name:"Anubhab",middleName:null,surname:"Mukherjee",slug:"anubhab-mukherjee",fullName:"Anubhab Mukherjee",position:null,profilePictureURL:"https://intech-files.s3.amazonaws.com/0033Y0000365PbRQAU/ProfilePicture%202022-04-15%2005%3A11%3A18.480",biography:"A former member of Laboratory of Nanomedicine, Brigham and Women’s Hospital, Harvard University, Boston, USA, Dr. Anubhab Mukherjee is an ardent votary of science who strives to make an impact in the lives of those afflicted with cancer and other chronic/acute ailments. He completed his Ph.D. from CSIR-Indian Institute of Chemical Technology, Hyderabad, India, having been skilled with RNAi, liposomal drug delivery, preclinical cell and animal studies. He pursued post-doctoral research at College of Pharmacy, Health Science Center, Texas A & M University and was involved in another postdoctoral research at Department of Translational Neurosciences and Neurotherapeutics, John Wayne Cancer Institute, Santa Monica, California. In 2015, he worked in Harvard-MIT Health Sciences & Technology as a visiting scientist. He has substantial experience in nanotechnology-based formulation development and successfully served various Indian organizations to develop pharmaceuticals and nutraceutical products. He is an inventor in many US patents and an author in many peer-reviewed articles, book chapters and books published in various media of international repute. Dr. Mukherjee is currently serving as Principal Scientist, R&D at Esperer Onco Nutrition (EON) Pvt. Ltd. and heads the Hyderabad R&D center of the organization.",institutionString:"Esperer Onco Nutrition Pvt Ltd.",institution:null},{id:"319365",title:"Assistant Prof.",name:"Manash K.",middleName:null,surname:"Paul",slug:"manash-k.-paul",fullName:"Manash K. Paul",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/319365/images/system/319365.png",biography:"Manash K. Paul is a Principal Investigator and Scientist at the University of California Los Angeles. He has contributed significantly to the fields of stem cell biology, regenerative medicine, and lung cancer. His research focuses on various signaling processes involved in maintaining stem cell homeostasis during the injury-repair process, deciphering lung stem cell niche, pulmonary disease modeling, immuno-oncology, and drug discovery. He is currently investigating the role of extracellular vesicles in premalignant lung cell migration and detecting the metastatic phenotype of lung cancer via machine-learning-based analyses of exosomal signatures. Dr. Paul has published in more than fifty peer-reviewed international journals and is highly cited. He is the recipient of many awards, including the UCLA Vice Chancellor’s award, a senior member of the Institute of Electrical and Electronics Engineers (IEEE), and an editorial board member for several international journals.",institutionString:"University of California Los Angeles",institution:{name:"University of California Los Angeles",country:{name:"United States of America"}}},{id:"311457",title:"Dr.",name:"Júlia",middleName:null,surname:"Scherer Santos",slug:"julia-scherer-santos",fullName:"Júlia Scherer Santos",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/311457/images/system/311457.jpg",biography:"Dr. Júlia Scherer Santos works in the areas of cosmetology, nanotechnology, pharmaceutical technology, beauty, and aesthetics. Dr. Santos also has experience as a professor of graduate courses. Graduated in Pharmacy, specialization in Cosmetology and Cosmeceuticals applied to aesthetics, specialization in Aesthetic and Cosmetic Health, and a doctorate in Pharmaceutical Nanotechnology. Teaching experience in Pharmacy and Aesthetics and Cosmetics courses. She works mainly on the following subjects: nanotechnology, cosmetology, pharmaceutical technology, aesthetics.",institutionString:"Universidade Federal de Juiz de Fora",institution:{name:"Universidade Federal de Juiz de Fora",country:{name:"Brazil"}}},{id:"219081",title:"Dr.",name:"Abdulsamed",middleName:null,surname:"Kükürt",slug:"abdulsamed-kukurt",fullName:"Abdulsamed Kükürt",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/219081/images/system/219081.png",biography:"Dr. Kükürt graduated from Uludağ University in Turkey. He started his academic career as a Research Assistant in the Department of Biochemistry at Kafkas University. In 2019, he completed his Ph.D. program in the Department of Biochemistry at the Institute of Health Sciences. He is currently working at the Department of Biochemistry, Kafkas University. He has 27 published research articles in academic journals, 11 book chapters, and 37 papers. He took part in 10 academic projects. He served as a reviewer for many articles. He still serves as a member of the review board in many academic journals. He is currently working on the protective activity of phenolic compounds in disorders associated with oxidative stress and inflammation.",institutionString:null,institution:{name:"Kafkas University",country:{name:"Turkey"}}},{id:"178366",title:"Dr.",name:"Volkan",middleName:null,surname:"Gelen",slug:"volkan-gelen",fullName:"Volkan Gelen",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/178366/images/system/178366.jpg",biography:"Volkan Gelen is a Physiology specialist who received his veterinary degree from Kafkas University in 2011. Between 2011-2015, he worked as an assistant at Atatürk University, Faculty of Veterinary Medicine, Department of Physiology. In 2016, he joined Kafkas University, Faculty of Veterinary Medicine, Department of Physiology as an assistant professor. Dr. Gelen has been engaged in various academic activities at Kafkas University since 2016. There he completed 5 projects and has 3 ongoing projects. He has 60 articles published in scientific journals and 20 poster presentations in scientific congresses. His research interests include physiology, endocrine system, cancer, diabetes, cardiovascular system diseases, and isolated organ bath system studies.",institutionString:"Kafkas University",institution:{name:"Kafkas University",country:{name:"Turkey"}}},{id:"418963",title:"Dr.",name:"Augustine Ododo",middleName:"Augustine",surname:"Osagie",slug:"augustine-ododo-osagie",fullName:"Augustine Ododo Osagie",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/418963/images/16900_n.jpg",biography:"Born into the family of Osagie, a prince of the Benin Kingdom. I am currently an academic in the Department of Medical Biochemistry, University of Benin. Part of the duties are to teach undergraduate students and conduct academic research.",institutionString:null,institution:{name:"University of Benin",country:{name:"Nigeria"}}},{id:"192992",title:"Prof.",name:"Shagufta",middleName:null,surname:"Perveen",slug:"shagufta-perveen",fullName:"Shagufta Perveen",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/192992/images/system/192992.png",biography:"Prof. Shagufta Perveen is a Distinguish Professor in the Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia. Dr. Perveen has acted as the principal investigator of major research projects funded by the research unit of King Saud University. She has more than ninety original research papers in peer-reviewed journals of international repute to her credit. She is a fellow member of the Royal Society of Chemistry UK and the American Chemical Society of the United States.",institutionString:"King Saud University",institution:{name:"King Saud University",country:{name:"Saudi Arabia"}}},{id:"49848",title:"Dr.",name:"Wen-Long",middleName:null,surname:"Hu",slug:"wen-long-hu",fullName:"Wen-Long Hu",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/49848/images/system/49848.jpg",biography:"Wen-Long Hu is Chief of the Division of Acupuncture, Department of Chinese Medicine at Kaohsiung Chang Gung Memorial Hospital, as well as an adjunct associate professor at Fooyin University and Kaohsiung Medical University. Wen-Long is President of Taiwan Traditional Chinese Medicine Medical Association. He has 28 years of experience in clinical practice in laser acupuncture therapy and 34 years in acupuncture. He is an invited speaker for lectures and workshops in laser acupuncture at many symposiums held by medical associations. He owns the patent for herbal preparation and producing, and for the supercritical fluid-treated needle. Dr. Hu has published three books, 12 book chapters, and more than 30 papers in reputed journals, besides serving as an editorial board member of repute.",institutionString:"Kaohsiung Chang Gung Memorial Hospital",institution:{name:"Kaohsiung Chang Gung Memorial Hospital",country:{name:"Taiwan"}}},{id:"298472",title:"Prof.",name:"Andrey V.",middleName:null,surname:"Grechko",slug:"andrey-v.-grechko",fullName:"Andrey V. Grechko",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/298472/images/system/298472.png",biography:"Andrey Vyacheslavovich Grechko, Ph.D., Professor, is a Corresponding Member of the Russian Academy of Sciences. He graduated from the Semashko Moscow Medical Institute (Semashko National Research Institute of Public Health) with a degree in Medicine (1998), the Clinical Department of Dermatovenerology (2000), and received a second higher education in Psychology (2009). Professor A.V. Grechko held the position of Сhief Physician of the Central Clinical Hospital in Moscow. He worked as a professor at the faculty and was engaged in scientific research at the Medical University. Starting in 2013, he has been the initiator of the creation of the Federal Scientific and Clinical Center for Intensive Care and Rehabilitology, Moscow, Russian Federation, where he also serves as Director since 2015. He has many years of experience in research and teaching in various fields of medicine, is an author/co-author of more than 200 scientific publications, 13 patents, 15 medical books/chapters, including Chapter in Book «Metabolomics», IntechOpen, 2020 «Metabolomic Discovery of Microbiota Dysfunction as the Cause of Pathology».",institutionString:"Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology",institution:null},{id:"199461",title:"Prof.",name:"Natalia V.",middleName:null,surname:"Beloborodova",slug:"natalia-v.-beloborodova",fullName:"Natalia V. Beloborodova",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/199461/images/system/199461.jpg",biography:'Natalia Vladimirovna Beloborodova was educated at the Pirogov Russian National Research Medical University, with a degree in pediatrics in 1980, a Ph.D. in 1987, and a specialization in Clinical Microbiology from First Moscow State Medical University in 2004. She has been a Professor since 1996. Currently, she is the Head of the Laboratory of Metabolism, a division of the Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russian Federation. N.V. Beloborodova has many years of clinical experience in the field of intensive care and surgery. She studies infectious complications and sepsis. She initiated a series of interdisciplinary clinical and experimental studies based on the concept of integrating human metabolism and its microbiota. Her scientific achievements are widely known: she is the recipient of the Marie E. Coates Award \\"Best lecturer-scientist\\" Gustafsson Fund, Karolinska Institutes, Stockholm, Sweden, and the International Sepsis Forum Award, Pasteur Institute, Paris, France (2014), etc. Professor N.V. Beloborodova wrote 210 papers, five books, 10 chapters and has edited four books.',institutionString:"Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology",institution:null},{id:"354260",title:"Ph.D.",name:"Tércio Elyan",middleName:"Azevedo",surname:"Azevedo Martins",slug:"tercio-elyan-azevedo-martins",fullName:"Tércio Elyan Azevedo Martins",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/354260/images/16241_n.jpg",biography:"Graduated in Pharmacy from the Federal University of Ceará with the modality in Industrial Pharmacy, Specialist in Production and Control of Medicines from the University of São Paulo (USP), Master in Pharmaceuticals and Medicines from the University of São Paulo (USP) and Doctor of Science in the program of Pharmaceuticals and Medicines by the University of São Paulo. Professor at Universidade Paulista (UNIP) in the areas of chemistry, cosmetology and trichology. Assistant Coordinator of the Higher Course in Aesthetic and Cosmetic Technology at Universidade Paulista Campus Chácara Santo Antônio. Experience in the Pharmacy area, with emphasis on Pharmacotechnics, Pharmaceutical Technology, Research and Development of Cosmetics, acting mainly on topics such as cosmetology, antioxidant activity, aesthetics, photoprotection, cyclodextrin and thermal analysis.",institutionString:null,institution:{name:"University of Sao Paulo",country:{name:"Brazil"}}},{id:"334285",title:"Ph.D. Student",name:"Sameer",middleName:"Kumar",surname:"Jagirdar",slug:"sameer-jagirdar",fullName:"Sameer Jagirdar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/334285/images/14691_n.jpg",biography:"I\\'m a graduate student at the center for biosystems science and engineering at the Indian Institute of Science, Bangalore, India. I am interested in studying host-pathogen interactions at the biomaterial interface.",institutionString:null,institution:{name:"Indian Institute of Science Bangalore",country:{name:"India"}}},{id:"329248",title:"Dr.",name:"Md. Faheem",middleName:null,surname:"Haider",slug:"md.-faheem-haider",fullName:"Md. Faheem Haider",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/329248/images/system/329248.jpg",biography:"Dr. Md. Faheem Haider completed his BPharm in 2012 at Integral University, Lucknow, India. In 2014, he completed his MPharm with specialization in Pharmaceutics at Babasaheb Bhimrao Ambedkar University, Lucknow, India. He received his Ph.D. degree from Jamia Hamdard University, New Delhi, India, in 2018. He was selected for the GPAT six times and his best All India Rank was 34. Currently, he is an assistant professor at Integral University. Previously he was an assistant professor at IIMT University, Meerut, India. He has experience teaching DPharm, Pharm.D, BPharm, and MPharm students. He has more than five publications in reputed journals to his credit. Dr. Faheem’s research area is the development and characterization of nanoformulation for the delivery of drugs to various organs.",institutionString:"Integral University",institution:{name:"Integral University",country:{name:"India"}}},{id:"329795",title:"Dr.",name:"Mohd Aftab",middleName:"Aftab",surname:"Siddiqui",slug:"mohd-aftab-siddiqui",fullName:"Mohd Aftab Siddiqui",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/329795/images/system/329795.png",biography:"Dr. Mohd Aftab Siddiqui is an assistant professor in the Faculty of Pharmacy, Integral University, Lucknow, India, where he obtained a Ph.D. in Pharmacology in 2020. He also obtained a BPharm and MPharm from the same university in 2013 and 2015, respectively. His area of research is the pharmacological screening of herbal drugs/natural products in liver cancer and cardiac diseases. He is a member of many professional bodies and has guided many MPharm and PharmD research projects. Dr. Siddiqui has many national and international publications and one German patent to his credit.",institutionString:"Integral University",institution:null}]}},subseries:{item:{id:"12",type:"subseries",title:"Human Physiology",keywords:"Anatomy, Cells, Organs, Systems, Homeostasis, Functions",scope:"Human physiology is the scientific exploration of the various functions (physical, biochemical, and mechanical properties) of humans, their organs, and their constituent cells. The endocrine and nervous systems play important roles in maintaining homeostasis in the human body. Integration, which is the biological basis of physiology, is achieved through communication between the many overlapping functions of the human body's systems, which takes place through electrical and chemical means. Much of the basis of our knowledge of human physiology has been provided by animal experiments. Because of the close relationship between structure and function, studies in human physiology and anatomy seek to understand the mechanisms that help the human body function. The series on human physiology deals with the various mechanisms of interaction between the various organs, nerves, and cells in the human body.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/12.jpg",hasOnlineFirst:!1,hasPublishedBooks:!0,annualVolume:11408,editor:{id:"195829",title:"Prof.",name:"Kunihiro",middleName:null,surname:"Sakuma",slug:"kunihiro-sakuma",fullName:"Kunihiro Sakuma",profilePictureURL:"https://mts.intechopen.com/storage/users/195829/images/system/195829.jpg",biography:"Professor Kunihiro Sakuma, Ph.D., currently works in the Institute for Liberal Arts at the Tokyo Institute of Technology. He is a physiologist working in the field of skeletal muscle. He was awarded his sports science diploma in 1995 by the University of Tsukuba and began his scientific work at the Department of Physiology, Aichi Human Service Center, focusing on the molecular mechanism of congenital muscular dystrophy and normal muscle regeneration. His interest later turned to the molecular mechanism and attenuating strategy of sarcopenia (age-related muscle atrophy). His opinion is to attenuate sarcopenia by improving autophagic defects using nutrient- and pharmaceutical-based treatments.",institutionString:null,institution:{name:"Tokyo Institute of Technology",institutionURL:null,country:{name:"Japan"}}},editorTwo:{id:"331519",title:"Dr.",name:"Kotomi",middleName:null,surname:"Sakai",slug:"kotomi-sakai",fullName:"Kotomi Sakai",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000031QtFXQA0/Profile_Picture_1637053227318",biography:"Senior researcher Kotomi Sakai, Ph.D., MPH, works at the Research Organization of Science and Technology in Ritsumeikan University. She is a researcher in the geriatric rehabilitation and public health field. She received Ph.D. from Nihon University and MPH from St.Luke’s International University. 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We encourage the submission of manuscripts that provide novel and mechanistic insights that report significant advances in the fields. Topics can include but are not limited to: Biotechnology such as biotechnological products and process engineering; Biotechnologically relevant enzymes and proteins; Bioenergy and biofuels; Applied genetics and molecular biotechnology; Genomics, transcriptomics, proteomics; Applied microbial and cell physiology; Environmental biotechnology; Methods and protocols. Moreover, topics in biosensor technology, like sensors that incorporate enzymes, antibodies, nucleic acids, whole cells, tissues and organelles, and other biological or biologically inspired components will be considered, and topics exploring transducers, including those based on electrochemical and optical piezoelectric, thermal, magnetic, and micromechanical elements. Chapters exploring biomaterial approaches such as polymer synthesis and characterization, drug and gene vector design, biocompatibility, immunology and toxicology, and self-assembly at the nanoscale, are welcome. Finally, the tissue engineering subcategory will support topics such as the fundamentals of stem cells and progenitor cells and their proliferation, differentiation, bioreactors for three-dimensional culture and studies of phenotypic changes, stem and progenitor cells, both short and long term, ex vivo and in vivo implantation both in preclinical models and also in clinical trials.",annualVolume:11405,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/9.jpg",editor:{id:"126286",title:"Dr.",name:"Luis",middleName:"Jesús",surname:"Villarreal-Gómez",fullName:"Luis Villarreal-Gómez",profilePictureURL:"https://mts.intechopen.com/storage/users/126286/images/system/126286.jpg",institutionString:null,institution:{name:"Autonomous University of Baja California",institutionURL:null,country:{name:"Mexico"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"35539",title:"Dr.",name:"Cecilia",middleName:null,surname:"Cristea",fullName:"Cecilia Cristea",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYQ65QAG/Profile_Picture_1621007741527",institutionString:null,institution:{name:"Iuliu Hațieganu University of Medicine and Pharmacy",institutionURL:null,country:{name:"Romania"}}},{id:"40735",title:"Dr.",name:"Gil",middleName:"Alberto Batista",surname:"Gonçalves",fullName:"Gil Gonçalves",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYRLGQA4/Profile_Picture_1628492612759",institutionString:null,institution:{name:"University of Aveiro",institutionURL:null,country:{name:"Portugal"}}},{id:"211725",title:"Associate Prof.",name:"Johann F.",middleName:null,surname:"Osma",fullName:"Johann F. 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