Position error statistic.
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Barely three months into the new year and we are happy to announce a monumental milestone reached - 150 million downloads.
\n\nThis achievement solidifies IntechOpen’s place as a pioneer in Open Access publishing and the home to some of the most relevant scientific research available through Open Access.
\n\nWe are so proud to have worked with so many bright minds throughout the years who have helped us spread knowledge through the power of Open Access and we look forward to continuing to support some of the greatest thinkers of our day.
\n\nThank you for making IntechOpen your place of learning, sharing, and discovery, and here’s to 150 million more!
\n\n\n\n\n'}],latestNews:[{slug:"intechopen-supports-asapbio-s-new-initiative-publish-your-reviews-20220729",title:"IntechOpen Supports ASAPbio’s New Initiative Publish Your Reviews"},{slug:"webinar-introduction-to-open-science-wednesday-18-may-1-pm-cest-20220518",title:"Webinar: Introduction to Open Science | Wednesday 18 May, 1 PM CEST"},{slug:"step-in-the-right-direction-intechopen-launches-a-portfolio-of-open-science-journals-20220414",title:"Step in the Right Direction: IntechOpen Launches a Portfolio of Open Science Journals"},{slug:"let-s-meet-at-london-book-fair-5-7-april-2022-olympia-london-20220321",title:"Let’s meet at London Book Fair, 5-7 April 2022, Olympia London"},{slug:"50-books-published-as-part-of-intechopen-and-knowledge-unlatched-ku-collaboration-20220316",title:"50 Books published as part of IntechOpen and Knowledge Unlatched (KU) Collaboration"},{slug:"intechopen-joins-the-united-nations-sustainable-development-goals-publishers-compact-20221702",title:"IntechOpen joins the United Nations Sustainable Development Goals Publishers Compact"},{slug:"intechopen-signs-exclusive-representation-agreement-with-lsr-libros-servicios-y-representaciones-s-a-de-c-v-20211123",title:"IntechOpen Signs Exclusive Representation Agreement with LSR Libros Servicios y Representaciones S.A. de C.V"},{slug:"intechopen-expands-partnership-with-research4life-20211110",title:"IntechOpen Expands Partnership with Research4Life"}]},book:{item:{type:"book",id:"10224",leadTitle:null,fullTitle:"Safety and Risk Assessment of Civil Aircraft during Operation",title:"Safety and Risk Assessment of Civil Aircraft during Operation",subtitle:null,reviewType:"peer-reviewed",abstract:"This book introduces safety and risk analysis methods for aircraft and aero-engines, design approaches for increasing safety and decreasing risk during operation, air traffic controllers’ attitudes to mistakes hazards, theories and models of human error occurrence during aircraft maintenance processes, and damage and failure analysis for composite structures.",isbn:"978-1-78984-793-2",printIsbn:"978-1-78984-792-5",pdfIsbn:"978-1-78985-055-0",doi:"10.5772/intechopen.90993",price:119,priceEur:129,priceUsd:155,slug:"safety-and-risk-assessment-of-civil-aircraft-during-operation",numberOfPages:210,isOpenForSubmission:!1,isInWos:null,isInBkci:!1,hash:"d966066f4fa44f6b320cd9b40ed66bbd",bookSignature:"Longbiao Li",publishedDate:"December 23rd 2020",coverURL:"https://cdn.intechopen.com/books/images_new/10224.jpg",numberOfDownloads:4445,numberOfWosCitations:0,numberOfCrossrefCitations:2,numberOfCrossrefCitationsByBook:0,numberOfDimensionsCitations:2,numberOfDimensionsCitationsByBook:0,hasAltmetrics:0,numberOfTotalCitations:4,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"January 8th 2020",dateEndSecondStepPublish:"March 15th 2020",dateEndThirdStepPublish:"May 30th 2020",dateEndFourthStepPublish:"July 8th 2020",dateEndFifthStepPublish:"October 1st 2020",currentStepOfPublishingProcess:5,indexedIn:"1,2,3,4,5,6,7",editedByType:"Edited by",kuFlag:!0,featuredMarkup:null,editors:[{id:"302409",title:"Dr.",name:"Longbiao",middleName:null,surname:"Li",slug:"longbiao-li",fullName:"Longbiao Li",profilePictureURL:"https://mts.intechopen.com/storage/users/302409/images/system/302409.jpg",biography:"Dr. Longbiao Li is a lecturer in the College of Civil Aviation at the Nanjing University of Aeronautics and Astronautics. Dr. Li’s research focuses on the vibration, fatigue, damage, fracture, reliability, safety and durability of aircraft and aero engine. In this research area, he is the first author of 184 SCI journal publications (49 JCR Q1), 8 monographs, 3 edited books, 3 textbooks, 3 book chapters, 30 Chinese Patents, 2 US Patents, 2 Chinese Software Copyright, and more than 20 refereed conference proceedings. He has been involved in different projects related to structural damage, reliability, and airworthiness design for aircraft and aero engines, supported by the Natural Science Foundation of China, COMAC Company, and AECC Commercial Aircraft Engine Company.",institutionString:"Nanjing University of Aeronautics and Astronautics",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"5",totalChapterViews:"0",totalEditedBooks:"3",institution:{name:"Nanjing University of Aeronautics and Astronautics",institutionURL:null,country:{name:"China"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,coeditorOne:null,coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"111",title:"Aerospace Engineering",slug:"aerospace-engineering"}],chapters:[{id:"73633",title:"Risk Assessment of Civil Aircraft during Operation",doi:"10.5772/intechopen.93557",slug:"risk-assessment-of-civil-aircraft-during-operation",totalDownloads:379,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"In this chapter, the risk assessment methods for aircraft system, structure, and aeroengine are investigated. For the aircraft system risk assessment, the probability level is divided into probable, improbable, and extremely improbable, and the hazard level of the failure condition is divided into minor, major, and catastrophic. Using Weibull analysis and Bayesian method to analyze the aircraft operation data, the risk level of aircraft system can be determined by combing methods provided in AC 25.1309-1A. For the aircraft structure risk assessment, the probability fracture mechanics approach can be used to determine the structure failure risk based on the data of material properties, environment, inspection, and so on. For the aeroengine risk assessment, the methods for classification of failure risk level, determination of hazard ratio, and calculation of the risk factor and risk per flight are given. The risk assessment process for aeroengine multi-failure modes based on the Monte Carlo simulation is presented to predict the occurrence of the failure and assess the failure risk.",signatures:"Longbiao Li",downloadPdfUrl:"/chapter/pdf-download/73633",previewPdfUrl:"/chapter/pdf-preview/73633",authors:[{id:"302409",title:"Dr.",name:"Longbiao",surname:"Li",slug:"longbiao-li",fullName:"Longbiao Li"}],corrections:null},{id:"73144",title:"Risk and Economic Analysis Methods of Commercial Aero Engines",doi:"10.5772/intechopen.93593",slug:"risk-and-economic-analysis-methods-of-commercial-aero-engines",totalDownloads:391,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"This chapter outlines the results of risk analysis and economic analysis of commercial aero engines during aircraft operation. Risk analysis is the procedure for identifying risk factors and assessing their significance, in essence, analysis of the likelihood that certain undesirable events may occur and as such adversely affect operation. Risk analysis includes risk assessment and methods to reduce risks or reduce adverse effects associated with it. Furthermore, economical analysis is a scientific way of understanding the essence of economic phenomena and processes, which in turn are based on dividing them into their constituent parts. In doing so, the variety of relationships and dependencies aimed at improving the associated work through the development and implementation of optimal solutions is studied. The purpose of the economic analysis is to give management of the actual state, and for persons who are not directly working with it, but are interested in its financial condition, the information necessary for an impartial judgment.",signatures:"Sherkhan Aitugan and Longbiao Li",downloadPdfUrl:"/chapter/pdf-download/73144",previewPdfUrl:"/chapter/pdf-preview/73144",authors:[{id:"302409",title:"Dr.",name:"Longbiao",surname:"Li",slug:"longbiao-li",fullName:"Longbiao Li"},{id:"318615",title:"Mr.",name:"Sherkhan",surname:"Aitugan",slug:"sherkhan-aitugan",fullName:"Sherkhan Aitugan"}],corrections:null},{id:"73525",title:"Safety and Risk Assessment of Civil Aircraft during Operation",doi:"10.5772/intechopen.93326",slug:"safety-and-risk-assessment-of-civil-aircraft-during-operation",totalDownloads:657,totalCrossrefCites:0,totalDimensionsCites:1,hasAltmetrics:0,abstract:"Risk and safety are always considered to be the most critical operational characteristics of civil aircraft. Typically, they relate to the possible occurrence of air traffic collisions that could result in loss of life, damage to infrastructure, and damage to property by third parties. Consequently, in addition to other adverse effects such as noise, air pollution, they were deemed externalities. Risk and protection became topics of continuous study, ranging from purely technical/technological aspects to explicitly administrative ones, due to their inherent very high importance. Such concerns require the establishment of appropriate regulations regarding designs and operations of device technology. In order assess the risk, there are several methods which include: identification of safety concerns, analysis of the risk factors likelihood, analysis of the risk factors severity, and assessment and the admissibility of risk factors. And finally, reducing of the risk should be performed by three general strategies which are: avoidance of the risk, reduction of risk, and isolation of the exposure. These strategies are implemented based on efficiency, technical measures, controlled measures, staffing measures, cost/benefit, practicality, acceptability of each party, durability, residual risk factor for flights safety, and new challenges. With the advancement of technology, new methods of risk deduction and safety concerns are being developed to ensure safe and risk-free flight operation.",signatures:"Asif Mostafa",downloadPdfUrl:"/chapter/pdf-download/73525",previewPdfUrl:"/chapter/pdf-preview/73525",authors:[{id:"317552",title:"Mr.",name:"Asif",surname:"Mostafa",slug:"asif-mostafa",fullName:"Asif Mostafa"}],corrections:null},{id:"72483",title:"Design Approaches for Safety Increasing and Risk Decreasing for the Civil Aircraft’s Operation",doi:"10.5772/intechopen.92560",slug:"design-approaches-for-safety-increasing-and-risk-decreasing-for-the-civil-aircraft-s-operation",totalDownloads:475,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"The safety and risks of civil aircraft operation depend on a lot of factors. One of them is the structural features of an aircraft. In aviation history, there are examples when “non-rational” design solution was the reason for crashes, but there are examples about successful civil aircraft that have “rational” structure and long operational time without critical incidents. So, how can a designer provide high safety of level and decrease incidents’ risks in time of a regular aircraft operation? This chapter partly can help to understand some reasons and approaches for providing “rational” aircraft structure. Design solutions can be divided into some groups by some common features and requirements. They are maintainability, serviceability, accessibility, labor effort decreasing, weather requirements, transportation, etc. All these groups depend on engineers’ structural solutions. They are interdependent and often contradictory. In other words, if one of the features will be better, another will be worse at the same time. And, a designer must remember all the time about this and try to find compromise between different requirements. The successful commercial aircraft is composed of a set of rational design solutions for these specific tasks.",signatures:"Dmytro Tiniakov",downloadPdfUrl:"/chapter/pdf-download/72483",previewPdfUrl:"/chapter/pdf-preview/72483",authors:[{id:"317710",title:"Associate Prof.",name:"Dmytro",surname:"Tiniakov",slug:"dmytro-tiniakov",fullName:"Dmytro Tiniakov"}],corrections:null},{id:"72416",title:"Theories and Models of Human Errors Occurrence. Simulation of Aircraft Maintenance Processes",doi:"10.5772/intechopen.92718",slug:"theories-and-models-of-human-errors-occurrence-simulation-of-aircraft-maintenance-processes",totalDownloads:519,totalCrossrefCites:1,totalDimensionsCites:0,hasAltmetrics:0,abstract:"General issues of the errors occurrence by technical personnel were considered, their causes and consequences. Classifications of errors based on an ergonomic understanding of their nature, as well as on the results of an engineering-psychological analysis of operators’ activity are given. Much attention is paid to the methods used by ICAO to classify errors and violations. Details considered models SHELL and J. Reason. Their adaptation is presented for analysis cases of the impact of the technical maintenance quality on the flight safety of aircraft. A special place is occupied by the disclosure of assessing issues impact of technical personnel errors on flight safety. A wide range of existing methods and models is presented, allowing obtaining qualitative and quantitative assessment of this effect in order for the prevention of errors by technical personnel and mitigating their consequences.",signatures:"Andrii Pryimak, Mykhailo Orlovskyi and Yevgeny Tretyakov",downloadPdfUrl:"/chapter/pdf-download/72416",previewPdfUrl:"/chapter/pdf-preview/72416",authors:[{id:"317911",title:"Ph.D.",name:"Pryimak",surname:"Andrii",slug:"pryimak-andrii",fullName:"Pryimak Andrii"},{id:"317985",title:"Dr.",name:"Orlovskyi",surname:"Mykhailo",slug:"orlovskyi-mykhailo",fullName:"Orlovskyi Mykhailo"},{id:"318001",title:"MSc.",name:"Tretyakov",surname:"Yevgeny",slug:"tretyakov-yevgeny",fullName:"Tretyakov Yevgeny"}],corrections:null},{id:"71609",title:"Air Traffic Controllers’ Attitude to the Mistakes Hazards during Their Professional Experience",doi:"10.5772/intechopen.91937",slug:"air-traffic-controllers-attitude-to-the-mistakes-hazards-during-their-professional-experience",totalDownloads:332,totalCrossrefCites:1,totalDimensionsCites:1,hasAltmetrics:0,abstract:"Air traffic controllers’ (ATCs) work process can be presented as uninterrupted set of decisions. These decisions occur and are implemented in both clear and stealth forms being influenced a lot. Determined and stochastic risks are especially important in this process. Human factor (HF) effect on flight safety is proven to be better considered through operators’ attitudes toward unsafe acts and conditions. This seamlessly integrates in ICAO safety paradigm. Air traffic controllers’ preferences system (PS) is discussed in regard to typical professional mistakes set. Using paired comparison, normative part of summary hazard and differentiating part of summary hazard, the preferences system of air traffic controllers is received. For the first time, mistakes pair summary hazard is determined on the unique qualimetric 100-point scale. Systems pair has high correlation level according to Spearman coefficient (R = 0.9727). Proposed Kendall rank coefficient outweighs the traditional one twice (Wtraditional = 0.2722, Wproposed = 0.55237). The significance level for all cases is equal to 1%. Multistep procedure of marginal opinions separation is implemented. It increased Kendall rank coefficient value up to Wproposed = 0.7. Survey procedure influenced positively on the ability of mistakes memorization, recognition, and avoidance during simulation training.",signatures:"Oleksii Reva, Andrii Nevynitsyn, Serhii Borsuk, Valerii Shulgin and Volodymyr Kamyshyn",downloadPdfUrl:"/chapter/pdf-download/71609",previewPdfUrl:"/chapter/pdf-preview/71609",authors:[{id:"304492",title:"Dr.",name:"Serhii",surname:"Borsuk",slug:"serhii-borsuk",fullName:"Serhii Borsuk"},{id:"305993",title:"Dr.",name:"Oleksii",surname:"Reva",slug:"oleksii-reva",fullName:"Oleksii Reva"},{id:"318265",title:"Dr.",name:"Andrii",surname:"Nevynitsyn",slug:"andrii-nevynitsyn",fullName:"Andrii Nevynitsyn"},{id:"318266",title:"Dr.",name:"Valerii",surname:"Shulgin",slug:"valerii-shulgin",fullName:"Valerii Shulgin"},{id:"318267",title:"Prof.",name:"Volodymyr",surname:"Kamyshyn",slug:"volodymyr-kamyshyn",fullName:"Volodymyr Kamyshyn"}],corrections:null},{id:"72754",title:"Non-Steady First Matrix Cracking of Fiber-Reinforced Ceramics",doi:"10.5772/intechopen.93060",slug:"non-steady-first-matrix-cracking-of-fiber-reinforced-ceramics",totalDownloads:309,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"Matrix cracking affects the reliability and safety of fiber-reinforced ceramic-matrix composites during operation. The matrix cracking can be divided into two types, that is, steady state crack and non-steady state cracking. This chapter is about the non-steady stable cracking of fiber-reinforced CMCs. The micro stress field of fiber, matrix, and interface shear stress along the fiber direction is analyzed using the shear-lag model. The relationship between the crack opening displacement and the crack surface closure traction is derived. The experimental first matrix cracking stress of different CMCs are predicted.",signatures:"Huan Wang",downloadPdfUrl:"/chapter/pdf-download/72754",previewPdfUrl:"/chapter/pdf-preview/72754",authors:[{id:"318545",title:"Ms.",name:"Huan",surname:"Wang",slug:"huan-wang",fullName:"Huan Wang"}],corrections:null},{id:"72938",title:"The Effect of Random Load on Life Prediction of High-Temperature Ceramic Matrix Composites",doi:"10.5772/intechopen.93059",slug:"the-effect-of-random-load-on-life-prediction-of-high-temperature-ceramic-matrix-composites",totalDownloads:297,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"High-temperature ceramic matrix composites (CMCs) are widely used in hot section components of aeroengine, and random loads have an important effect on their safety and reliability during aircraft operation. The current fatigue life prediction model of CMC is divided into macrophenomenon model and microdamage mechanism model. In this chapter, the fatigue life of fiber-reinforced ceramic matrix composites is investigated. The fatigue life of the fiber-reinforced ceramic matrix composites is predicted by micromechanical methods. The effect of random loading on fatigue life is analyzed and compared with constant peak stress fatigue life. The influence of composite constitutive properties on fatigue fracture is also discussed.",signatures:"En-Zhong Zhang",downloadPdfUrl:"/chapter/pdf-download/72938",previewPdfUrl:"/chapter/pdf-preview/72938",authors:[{id:"318614",title:"Dr.",name:"En-Zhong",surname:"Zhang",slug:"en-zhong-zhang",fullName:"En-Zhong Zhang"}],corrections:null},{id:"72943",title:"Multiple Matrix Cracking of Fiber-Reinforced Ceramic-Matrix Composites during Operation",doi:"10.5772/intechopen.93074",slug:"multiple-matrix-cracking-of-fiber-reinforced-ceramic-matrix-composites-during-operation",totalDownloads:325,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"In the field of civil aviation, the most important factor is safety quality. Improving aircraft performance can increase flight safety factor in some degree. To improve the thrust-to-weight ratio of aircraft engines and reduce fuel consumption, the fundamental measure is to increase the turbine inlet temperature of engines, while hot-section components is directly related to the maximum allowable operating temperature. Ceramic-matrix composite (CMC) material is one of the important candidate materials for aeroengine. To improve CMCs in aircraft engine application, it is necessary to investigate the failure mechanism of CMCs and also failure models. However, during operation, matrix multiple cracking occurs with fiber debonding and fracture, which affects the flight safety and failure risk. In this chapter, the multiple matrix cracking of fiber-reinforced CMCs is investigated using energy balance approach.",signatures:"Chengzheng Zhu",downloadPdfUrl:"/chapter/pdf-download/72943",previewPdfUrl:"/chapter/pdf-preview/72943",authors:[{id:"317640",title:"Mr.",name:"Chengzheng",surname:"Zhu",slug:"chengzheng-zhu",fullName:"Chengzheng Zhu"}],corrections:null},{id:"72665",title:"Finite Element Analysis of Fiber Pull-Out of Ceramic Matrix Composites",doi:"10.5772/intechopen.93082",slug:"finite-element-analysis-of-fiber-pull-out-of-ceramic-matrix-composites",totalDownloads:373,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"Ceramic matrix composites (CMCs) are widely used in aerospace, defense industry, and other fields because of their high strength, high toughness, and high temperature resistance. The interface phase with matching performance and structural coordination is the key element to improve the brittleness of CMCs and improve their strength and toughness. In this chapter, based on the fiber pull-out experiment, using the cohesive zone model as the interface element model, a two-dimensional axisymmetric fiber pull-out finite element model was established and simulated. The results show that within a certain range, higher interface bonding strength and interface fracture energy increase the maximum debonding load during fiber pull-out and enhance the material bearing capacity.",signatures:"Wang Hong",downloadPdfUrl:"/chapter/pdf-download/72665",previewPdfUrl:"/chapter/pdf-preview/72665",authors:[{id:"322410",title:"Mr.",name:"Wang",surname:"Hong",slug:"wang-hong",fullName:"Wang Hong"}],corrections:null},{id:"73524",title:"Modeling of Damage Evolution of Fiber-Reinforced Composite Structure",doi:"10.5772/intechopen.93323",slug:"modeling-of-damage-evolution-of-fiber-reinforced-composite-structure",totalDownloads:389,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"This chapter is the result of a study of many special disciplines, such as damage of matrix, cracking, interface, debonding, and fiber failure. A damage mechanics model is presented to characterize brittle failure in elastic fiber-reinforced composite materials. During the life of the aircraft, cracks and damage can occur in aviation structures that should be analyzed to determine the decrease in stiffness and resistance due to the presence of the cracks. Theoretical and numerical problems related to intralaminar and interlaminar failure modeling are very well discussed. The formulations of the constitutive models presented in this chapter support the Continuum Damage Mechanics (CDM) approach and enable the control of energy dissipation in relation to each failure mode, regardless of the refinement of the network and the orientation of the fracture plane. In context to CDM, internal thermodynamic irreversible damage variables are defined to quantify the damage concentration in relation to each possible failure mode and to predict the gradual reduction in stiffness for each bond layer. Numerical examples are provided to possibly explain the capabilities of the model.",signatures:"Muhammad Bilal Afzal",downloadPdfUrl:"/chapter/pdf-download/73524",previewPdfUrl:"/chapter/pdf-preview/73524",authors:[{id:"318682",title:"B.Sc.",name:"Muhammad",surname:"Bilal Afzal",slug:"muhammad-bilal-afzal",fullName:"Muhammad Bilal Afzal"}],corrections:null}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"},subseries:null,tags:null},relatedBooks:[{type:"book",id:"7404",title:"Hysteresis of Composites",subtitle:null,isOpenForSubmission:!1,hash:"8540fa2378dbb92e50411cfebfb853a6",slug:"hysteresis-of-composites",bookSignature:"Li Longbiao",coverURL:"https://cdn.intechopen.com/books/images_new/7404.jpg",editedByType:"Edited by",editors:[{id:"302409",title:"Dr.",name:"Longbiao",surname:"Li",slug:"longbiao-li",fullName:"Longbiao Li"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10690",title:"Air Traffic Management and Control",subtitle:null,isOpenForSubmission:!1,hash:"9b3aae480119950f33ef5b33f43c2598",slug:"air-traffic-management-and-control",bookSignature:"Longbiao Li",coverURL:"https://cdn.intechopen.com/books/images_new/10690.jpg",editedByType:"Edited by",editors:[{id:"302409",title:"Dr.",name:"Longbiao",surname:"Li",slug:"longbiao-li",fullName:"Longbiao Li"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"8613",title:"Aerospace Engineering",subtitle:null,isOpenForSubmission:!1,hash:"075278075d72ebe02490ff58675119ef",slug:"aerospace-engineering",bookSignature:"George Dekoulis",coverURL:"https://cdn.intechopen.com/books/images_new/8613.jpg",editedByType:"Edited by",editors:[{id:"9833",title:"Prof.",name:"George",surname:"Dekoulis",slug:"george-dekoulis",fullName:"George Dekoulis"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"7571",title:"Aviation and Its Management",subtitle:"Global Challenges and Opportunities",isOpenForSubmission:!1,hash:"6c1503ac6f4d2bba190dbe2af0716b0b",slug:"aviation-and-its-management-global-challenges-and-opportunities",bookSignature:"Arif Sikander",coverURL:"https://cdn.intechopen.com/books/images_new/7571.jpg",editedByType:"Edited by",editors:[{id:"253791",title:"Dr.",name:"Arif",surname:"Sikander",slug:"arif-sikander",fullName:"Arif Sikander"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"1591",title:"Infrared Spectroscopy",subtitle:"Materials Science, Engineering and Technology",isOpenForSubmission:!1,hash:"99b4b7b71a8caeb693ed762b40b017f4",slug:"infrared-spectroscopy-materials-science-engineering-and-technology",bookSignature:"Theophile Theophanides",coverURL:"https://cdn.intechopen.com/books/images_new/1591.jpg",editedByType:"Edited by",editors:[{id:"37194",title:"Dr.",name:"Theophile",surname:"Theophanides",slug:"theophile-theophanides",fullName:"Theophile Theophanides"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3161",title:"Frontiers in Guided Wave Optics and Optoelectronics",subtitle:null,isOpenForSubmission:!1,hash:"deb44e9c99f82bbce1083abea743146c",slug:"frontiers-in-guided-wave-optics-and-optoelectronics",bookSignature:"Bishnu Pal",coverURL:"https://cdn.intechopen.com/books/images_new/3161.jpg",editedByType:"Edited by",editors:[{id:"4782",title:"Prof.",name:"Bishnu",surname:"Pal",slug:"bishnu-pal",fullName:"Bishnu Pal"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"371",title:"Abiotic Stress in Plants",subtitle:"Mechanisms and Adaptations",isOpenForSubmission:!1,hash:"588466f487e307619849d72389178a74",slug:"abiotic-stress-in-plants-mechanisms-and-adaptations",bookSignature:"Arun Shanker and B. 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\r\n\tHistorically, human society has been experiencing a process of change thanks to globalization and its underlying economic development. These changes involve factors that are not visible to the common denominator of the inhabitants of the world, especially for developing regions, countries with emerging economies, and communities for whom the negative impact of this globalization is greater. The so-called progress and the cost of the latter implies a mercantile production of companies, transnationals, and large economic groups that can be translated into the perpetuation of the cycle of social segregation, especially for historically excluded groups.
\r\n\tGlobalization does not represent a pure and generous process for humanity or other species, but rather it implies social exclusion and also provokes situations of vulnerability in groups of people, forced exclusion, and apartheid: poor job opportunities, lack of access to education, worse socio-sanitary conditions. Specifically, it can be said that social segregation entails the apartheid of social groups of different ages, genders, and ethnicities; these groups live a reality manifested through the deepening of poverty, in terms of increased vulnerability of the poor and groups with little economic, social, cultural, labor and health stability.
\r\n\tThis book aims to talk about some topics that are neglected in the discourses of academic communities and political elites. The inequality process is deeply rooted among humans and is part of many people's lives in the form of modern apartheid, gender segregation, lack of health access, and cultural gap. All those structural inequality processes are the product of the biopower perpetuated and produced in the macrosystem, exosystem, mesosystem, and microsystem. For many people from the academy, the information-consuming public, and the society in general, it is a problem to talk about these processes, since they have either lost interest or have normalized the structural and social inequity. For this reason, we see it as transcendental to explain how this situation occurs from the most internal fibers to the most evident processes, intending to make it more visible and thus expose the situation for possible solutions.
",isbn:"978-1-83768-406-9",printIsbn:"978-1-83768-405-2",pdfIsbn:"978-1-83768-407-6",doi:null,price:0,priceEur:0,priceUsd:0,slug:null,numberOfPages:0,isOpenForSubmission:!0,isSalesforceBook:!1,isNomenclature:!1,hash:"cefab077e403fd1695fb2946e7914942",bookSignature:"Ph.D. Yaroslava Robles-Bykbaev",publishedDate:null,coverURL:"https://cdn.intechopen.com/books/images_new/11473.jpg",keywords:"Wage Gap, Gender Segregation, Fundamental Human Rights, Health Access, Social Inequity Processes, Modern Apartheid, Resilience, Cultural Gaps, Globalization, Geopolitics of Social Inequality, Public Policies, Social Vulnerability",numberOfDownloads:null,numberOfWosCitations:0,numberOfCrossrefCitations:null,numberOfDimensionsCitations:null,numberOfTotalCitations:null,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"June 15th 2022",dateEndSecondStepPublish:"July 13th 2022",dateEndThirdStepPublish:"September 11th 2022",dateEndFourthStepPublish:"November 30th 2022",dateEndFifthStepPublish:"January 29th 2023",dateConfirmationOfParticipation:null,remainingDaysToSecondStep:"a month",secondStepPassed:!0,areRegistrationsClosed:!1,currentStepOfPublishingProcess:3,editedByType:null,kuFlag:!1,biosketch:"Dr. Bykbaev is a member of the UNESCO Chair of Politecnica Salesiana University. She has contributed as co-author and author to approximately thirty scientific publications in the field of statistics, inclusive education, and social and cultural anthropology. These publications focus on the visibility of problems in the field of public health and focus on the creation of proposals to improve community health. Dr. Bykbaev is an active member of the NODO Ecuadorian Network of Women Scientists (REMCI).",coeditorOneBiosketch:null,coeditorTwoBiosketch:null,coeditorThreeBiosketch:null,coeditorFourBiosketch:null,coeditorFiveBiosketch:null,editors:[{id:"313341",title:"Ph.D.",name:"Yaroslava",middleName:null,surname:"Robles-Bykbaev",slug:"yaroslava-robles-bykbaev",fullName:"Yaroslava Robles-Bykbaev",profilePictureURL:"https://mts.intechopen.com/storage/users/313341/images/system/313341.jpg",biography:null,institutionString:"Politecnica Salesiana University",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"0",totalChapterViews:"0",totalEditedBooks:"0",institution:{name:"Politecnica Salesiana University",institutionURL:null,country:{name:"Ecuador"}}}],coeditorOne:null,coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"23",title:"Social Sciences",slug:"social-sciences"}],chapters:null,productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"},personalPublishingAssistant:{id:"444316",firstName:"Blanka",lastName:"Gugic",middleName:null,title:"Mrs.",imageUrl:"https://mts.intechopen.com/storage/users/444316/images/20016_n.jpg",email:"blanka@intechopen.com",biography:"As an Author Service Manager, my responsibilities include monitoring and facilitating all publishing activities for authors and editors. From chapter submission and review to approval and revision, copyediting and design, until final publication, I work closely with authors and editors to ensure a simple and easy publishing process. I maintain constant and effective communication with authors, editors and reviewers, which allows for a level of personal support that enables contributors to fully commit and concentrate on the chapters they are writing, editing, or reviewing. I assist authors in the preparation of their full chapter submissions and track important deadlines and ensure they are met. I help to coordinate internal processes such as linguistic review, and monitor the technical aspects of the process. As an ASM I am also involved in the acquisition of editors. 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The study in [1] estimated that the global indoor localization market is expected to grow from its value of $935.05 million in 2014 to approximately $4.42 billion in 2019, corresponding to an estimated compound annual growth rate (CAGR) of 36.5%. The estimation of mobile locations has an important role in many computing applications. The global positioning system (GPS) is one of the most common location-based systems, but it cannot be used inside buildings as a direct line of sight (LOS) is required between the GPS receiver and the satellite to identify the user’s location. Therefore, a large number of technologies, such as Bluetooth, radiofrequency identification (RFID), wireless local area network (WLAN or Wi-Fi), magnetic field variations, ultrasound, Zigbee, and light-emitting diode (LED) light bulbs, have been developed to create high-accuracy indoor positioning systems (IPS), with Wi-Fi being the most commonly used technology. Most smartphones can obtain received signal strength (RSS) from the access points (APs) of WLANs because of the low cost and existing WLAN infrastructure [2, 3]
The IPS algorithm that uses RSS-based indoor localization can be classified into two main types: log-distance propagation model (PM) algorithms based on the signal and fingerprinting indoor localization based on the data collected. IPS based on signal propagation is divided into lateration and angulation. The main idea of lateration estimation is to calculate the distance between the smartphone and AP using geometry and signal measurement information, such as the time of arrival (TOA), time difference of arrival (TDOA), and angle of arrival (AOA), of the incoming signals from APs. In general, propagation signals suffer from non-line-of-sight (NLOS) multipath signals due to the presence of walls and furniture and the movement of people. In addition, the signal accuracy decreases if one or more AP coordinates are not accurately calculated. All of these drawbacks have made it difficult to estimate an object’s position using signal propagation [4]. Thus, fingerprinting-based localization systems have been proposed as an alternative technology [5] as they do not require infrastructure. Instead, they use the existing WLAN in the building and the smartphone, which relies on the spectrum of the RSS from the APs to the location to estimate the user’s location coordinates.
The fingerprint-based technique is divided into offline and online phases. In the offline phase, the entire area of interest is divided into a rectangular set of grid points, and at each point, a site survey is taken by recording the RSS from APs, which is then stored in a database called the radio map [6, 7, 8, 9, 10]. In the online phase, the smartphone collects the RSS from the APs and sends it to the server to compare the predefined fingerprint of the offline phase with the RSS in the online phase in order to estimate the location on the grid map, as shown in Figure 1.
The offline and online stages of location Wi-Fi-based fingerprinting architecture.
The k-nearest neighbor (kNN) algorithm is one of the simplest ways to estimate location; it depends upon the Euclidean distance to measure the similarity/dissimilarity between the offline and online phases. Even though this algorithm is easy to implement, it has low accuracy. Other methods such as statistical learning and Bayesian modeling have also been used to estimate the location of an object. Accuracy is one of the most important requirements of IPS.
Mean distance error is typically used as the performance metric and is calculated as the average Euclidean distance between the actual location and the estimated location.
Recently, an important issue was raised about the variation of signal propagation, namely, the question of how signals are able to propagate over time in the same place in the presence of multiple factors, such as physical obstructions, radiofrequency (RF) equipment, and the presence of human bodies. These factors can lead to attenuation and multipath issues, thereby causing gradual changes in the signal that can reduce the accuracy of the localization system [11]. The values stored in fingerprint maps represent the mean value of the received signal strength indicator (RSSI). Some approaches presume that the RSSI distribution is Gaussian [12], whereas others assume a non-Gaussian distribution, such as those described in [13]. Using Wi-Fi localization systems to estimate the location of an object has many advantages compared with other technologies, such as availability and low cost. However, because the RSSI signal uses both offline and online phases, hardware variance can significantly degrade the positional accuracy of these systems. Some studies have investigated this variance; for example, it was reported in [11] that when using different smartphones to collect RSSI data at the same time and same location, some phones consistently had higher RSSI values than others. The orientation of the user can also contribute to the variance of the RSSI signal because the human body can be a significant attenuator.
This hardware variance problem in Wi-Fi localization has also been noticed in Cisco location systems [11]; some signals were found to be omitted when a different device was used in the online phase compared with the offline phase.
This chapter presents the following:
We propose the use of Jensen-Bregman divergence (JBD) as a WLAN-based method and a Kullback-Leibler multivariate Gaussian (
We propose a procedure with high characterization distribution. The RSS values were taken from four different orientations (45, 135, 225, and 315°) to prevent body-blocking effects, with a scan performed for 100 s in each direction to reduce the effects of signal variation.
JBD and
Global navigation satellite systems (GNSS) such as GLONASS (Russia’s version of GPS), GALILEO, and GPS work well in outdoor environments, but their accuracy can significantly decrease in indoor environments due to many factors, such as penetration loss, refraction, multipath propagation, and absorption. Therefore, it is important to develop a system that can work in indoor environments with high accuracy. To this end, many techniques have been proposed for IPS in the last decade. In model-based techniques, the location is estimated based on a geometrical model, such as the log-distance path loss (LDPL) model, in which a semi-statistical function is built on the relationship between the RF propagation function and the RSS value. Several approaches have been proposed that are trade-offs between accuracy and cost, such as TOA, TDOA, AOA, and multidimensional scaling (MDS). MDS is a set of statistical techniques that are used to visualize the information in order to find similarities/dissimilarities in the data. The matrix in MDS begins with item-item dissimilarities, and AP-AP distances are determined by a radio attenuation model [9]. The fingerprinting-based technique depends on matching algorithms (e.g., kNN) that have been used in RADAR [14], which is one of the first Wi-Fi signal strength-based IPS and is considered the basis of WLAN fingerprinting IPS. Many developed kNN algorithms have been proposed for determining the similarity/dissimilarity in metrics, which is usually done using the Manhattan or Euclidean distance, such as in [11, 12, 13, 14, 15, 16, 17, 18]. Ref. [19] proposed a new version of kNN that is more efficient than the probabilistic methods, neural networks, and traditional kNN, as it relies upon the decision tree of the training phases and takes into account the average of reference point (RP) measurements instead of needing the entire dataset to estimate the object’s location. Ref. [20] performed a modified deterministic kNN technique with Mahalanobis, Manhattan, and Euclidian distances and found the Manhattan distance to be the most accurate. Recently, the use of probabilistic distribution measurements in many IPS applications has increased. The authors in [21] pioneered the use of the probabilistic distribution measurement in IPS and proposed a probabilistic framework by using the Bayesian network to estimate the location. In [22] the authors used a modified probability neural network (MPNN) to estimate the coordinates of the object and found that it outperformed the triangulation method. In [23], a kernel method was proposed to estimate the object’s location using a histogram of the RSSI at the unknown location. In [24], the probability density function (PDF) was estimated using the Kullback-Leibler divergence (KLD) framework for composite hypothesis testing between the fingerprinting database and the test point, whereas in [25], the authors assumed that the RSSI distribution was multivariate Gaussian and used the KLD to estimate the impacts of the RPs on the test point in order to estimate the probability of the closest one and to identify the coordinates of the test point.
In [26], the RSS-based Bluetooth low-energy localization technique was used to establish the fingerprint, after which the KLD was used in probabilistic kernel regression to estimate the object’s location. The results showed this method to be accurate to approximately 1 m in an office environment. In general, the KLD kernel regression performs better in a multimodal distribution. In [27], the KLD was used to estimate the probabilistic kernel of both Gaussian and non-Gaussian distributions in order to compare them and to determine their limitations.
We begin with a typical WLAN scenario in which a person carries a smartphone device with WLAN access and takes RSS measurements from different APs within the College of Engineering and Applied Sciences (CEAS) at Western Michigan University (WMU). It is commonly assumed that the RSSI from multiple APs is distributed as a multimodal signal, as noted in [16]. However, in our study, the recorded signal-to-noise ratio for a single device varied significantly at any one location, with the values differing by as much as 10 dBm. Specifically, the signal-to-noise values were recorded for 35 min during rush hour for a single AP and in the same location.
There are many parameters that can affect the shape of the signal, such as reflection, diffraction, and pedestrian traffic. In this study, we sought to find a scenario that would lead to a better distribution of the Wi-Fi signal. During the offline phase, a realistic scenario was created that took into account the variation of the signal. However, because the effects of the body of the person holding the phone as well as pedestrian traffic can change the variation of the signal, a recording of the RSS was taken in four directions (45, 135, 225, and 315°) to reduce these variations. At each RP, a raw set of RSS data were collected as a time sample from the APs in the area of interest, denoted as
where
where
where
During the online phase, the RSS measurement is denoted as
Another approach, specifically the KLMvG model, has recently been used in fingerprinting-based methods to estimate the position of the objects. This model exploits the interdependencies between the RPs, such as the signal model and the geometry that can be quantified to find the correlations among the RPs. Milioris [29] proposed a KLMvG model to measure the similarity between the RSS measurements of test points and the RPs, defined as
where S represents the matrix of RSS values from the different APs at specific locations and j represents the cell of the fingerprint location where
where σ is the kernel smoothing factor. The probability will be equal to 1 if p = q, and the output will decrease when the difference between p and q becomes larger. The Kullback-Leibler multivariate Gaussian positioning method.
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In recent times, approaches that measure the distortion in classes have become more common, instead of depending on a single distance. Indeed, the analysis of distortion is being used in many applications of machine learning, computational geometry, and IPS. Using Bregman divergence to measure the similarity/dissimilarity has recently become an attractive method because it encapsulates both information-theoretic relative entropy and the geometric Euclidean distance, which is a meta-algorithm [30]. The Bregman distance
where
and
The Bregman divergence unifies the statistical KLD with the squared Euclidean distance by defining the distortion measurement in classes:
The Euclidean distance is obtained from the Bregman divergence by considering the convex function as
The KLD is also a Bregman divergence if the convex function used is
The Bregman divergence represents the vertical distance between the potential function and the hyperplane at q.
In information theory, the Shannon differential entropy measures the amount of uncertainty of a random variable:
The KLD is equal to the cross entropy of two discrete distributions minus the Shannon differential entropy [31]:
where
and S is the set of vectors of the RSS. In general, the Bregman divergence is not symmetrical, but it can symmetrize as follows:
In the same manner, Jeffreys’ divergence symmetrizes the oriented KLD as follows:
Such information-theoretic divergence has two major drawbacks: first, the output can be undefined if q = 0 and p ≠ 0, and second, the J-divergence is not bound by terms of metric distance. To avoid these drawbacks and avoid the log(0) or to divide by 0, the authors in [32] proposed a new divergence called K-divergence:
By introducing the K-divergence, [30] produced the Jensen-Shannon divergence (JSD) as follows:
The JSD can be defined, bound by an L1-metric, and finite. In the same vein, the Bregman divergence can be symmetrized as
for d-dimensional multivariate data:
where q represents the fingerprint dataset and p, which is the dataset of the test points, represents the APs that the mobile device received. Because
Interpreting the Jensen-Bregman divergence.
In general, for a positive definite matrix, the Jensen-Bregman divergence contains the generalized quadratic distance, which is known as the Mahalanobis distance:
To improve accuracy, we present Algorithm 2: The Kullback-Leibler multivariate Gaussian positioning method
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The proposed algorithm evaluations will be presented in the subsequent subsections; the algorithms were implemented on the first floor of the CEAS at WMU. To collect the data sample, a Samsung S5 smartphone with operating system 4.4.2 was used. The proposed algorithms were implemented on an HP Pavilion using Java software with an Eclipse framework. Cisco Linksys E2500 Advanced Simultaneous Dual-Band Wireless-N Routers were used in the area of interest. Most of this work discounted the variation of the RSS from the APs.
To evaluate the performance of the different fingerprinting techniques, the localization error was computed as the Euclidean distance between the actual reported coordinates of the test points and the coordinates of the mobile user during the online phase. The number of RSS of the APs and the number of nearest neighbors were noted, as they can affect the accuracy of the algorithms. The number of APs can play an important role in the accuracy of the distance error, which can distinguish near RPs from those further away.
To evaluate the performance of the different fingerprinting techniques, the localization error was computed as the Euclidean distance between the actual reported coordinates of the test points and the coordinates of the mobile user during the online phase. The number of RSS of the APs and the number of nearest neighbors were noted, as they can affect the accuracy of the algorithms. The number of APs can play an important role in the accuracy of the distance error, which can distinguish near RPs from those further away.
In order to measure the impact of the APs on the accuracy, we used a specific number of nearest neighbors with a variety of APs. However, that resulted in a longer RSS scanning interval, which slowed the process down. As a result, the online phase comprised five time samples, which took 1 s for Wi-Fi scanning on the device. To investigate the accuracy of our proposed algorithm, different algorithms were used, such as PNN and KNN, and compared with our proposed algorithm. Different numbers of nearest neighbors were used to estimate the location of the object and to evaluate the performance of our system framework.
Figure 4 shows the impact of different APs when five nearest neighbors were used. The lowest localization error was obtained when 22 APs were used: 0.98 m for kJBD, 1.12 m for kJSD, 1.16 m for KLMvG, 1.34 m for PNN, and 1.38 m for kNN. Greater accuracy was obtained when more nearest neighbors were used, as illustrated in Figure 5.
Error distance estimation with respect to APs with five nearest neighbors.
Error distance estimation with respect to APs with 20 nearest neighbors.
The lowest localization accuracy was also obtained when 22 APs were used: 0.92 m for kJBD, 1.01 m for kJSD, 1.02 m for KLMvG, 1.097 m for PNN, and 1.19 m for kNN. More improvements in system accuracy were noticed when 80 nearest neighbors were used: 0.865 m for kJBD, 0.96 m for kJSD, 0.99 m for KLMvG, 0.995 m for PNN, and 1.12 m for kNN, as shown in Figure 6.
Error distance estimation with respect to APs with 80 nearest neighbors.
Figure 7 illustrates the corresponding cumulative probability distributions of the localization error for the three methods. In particular, the median errors for kJBD were 0.89 m, 0.98 m for kJSD, and 1.02 m for KLMvG. Furthermore, an accuracy of 90% was achieved at 2.13 m for KLMvG and 1.93 m for kJSD, with the best accuracy obtained at 2.13 m for kJSD.
Experiment results: the CDF of localization error when using 80 nearest neighbors.
To validate our work, a comparison was made between the proposed algorithms with other algorithms from prior works, such as kNN [14], compressive sensing [28], and the kernel-based method [33], as illustrated in Table 1.
IPS incorporates the power of GPS and indoor mapping and has many potential applications, for example, by emergency healthcare services, by people with impaired vision, and for navigating unfamiliar complex buildings where it is easy to get disoriented or lost (e.g., malls, airports, subways). A fingerprint map was created for a segment of the CEAS in order to utilize the relationship between different RSS readings. Different algorithms were used and compared using different approaches, including kNN and PNN, and their performances assessed for a number of APs. The results were quite adequate for the indoor environment with an average error of less than 1 m. The kJBD had the highest accuracy when there were 80 nearest neighbors with 22 APs. We are currently in the process of investigating position prediction error distributions and quantifying the localization variation of Wi-Fi signal distribution in space
For improved academic achievement and acceptable reading proficiency levels, learners need to vigorously engage on varying reading activities. When they work as groups, they tend to learn from one another through collaboration, information sharing, and mentoring each other. There have been identified benefits of working as groups when primary school learners learn an unfamiliar language in the schools studied, this being referred to English language learning [1]. Research reveals that for primary school learners to engage in the form of groups during the processes of language learning and teaching, there are enriched social skills that are acquired, including cooperation and accountability, as such it becomes easy for learners to break down compound tasks into minor and convenient packages [2]. The main benefits of group work when developing language proficiency among learners include cultivated discussions and justifications, let alone contesting learner assumptions, yet the ultimate goal being emerging robust communication skills. This strategy has been observed to curb problems of shyness, lowered self-esteem coupled with self-motivation [3]. As emergent readers, learners in the primary school need daily continued engagement with reading exercises as learning to read has been recently regarded as one of the core educational objectives not for English language learning only, but across all the subjects underpinning the curriculum as there are also texts to be comprehended.
However, in the previously known South African schools’ classroom environment prior COVID-19 pandemic era, policy advocated for formation of learner groupings as learning and teaching has to be learner-centered and learner-paced, this being prescribed by the Curriculum and Assessment Policy Statements (CAPS) [4]. English language teachers, through this arrangement, would proudly report on escalating learner achievements that used to be paired up with improved reading proficiency levels. This makes us as authors of this manuscript to acknowledge the importance of group work. To our perception, working as groups when learning a language leads to a more effective and fun collaboration as learners with diverse learning styles and learning abilities are granted an opportunity to engage with others, thereby anticipating the comprehended text from diverse perspectives, yet promoting confidence levels and expanded listening, thinking, speaking, and writing skills. All these are regarded as the core language skills for language learning [5]. For learners to be successful, efficient, and effective scholars, these skills need to be mastered.
Grouping of learners when studying a language has been proved to lead to progress and success in academic achievement [6]. Teamwork is of real importance as learners engaging in this manner were identified to have exhibited better achievement levels when compared with those who preferred to study or learn in a single-handed mode. Henceforth, there is a vital need for English language teachers to be quite conversant that indeed group work has some profits and therefore are expected to apply such strategy during the processes of teaching and learning.
On the other side, social distancing protocols emanating from COVID-19 regulations have resulted in schools being left with no other option than to disband the previously formulated classroom learner groupings [7]. One may ask himself, what then has the current state of the existing new normal put primary school language teachers together with the learners as recipients in the teaching-learning process, as previously been observed by the authors that this cohort of teachers has full confidence for language development when comprehending texts is handled not in an individual perspective, but by learners specifically arranged as groups to interact, engage, thereby learning as peers. Furthermore, learners in the studied schools got intimidated by the abrupt changes in the schooling situation more so that learning English language, being unfamiliar hence not their home language, needs to be nurtured. By so doing, learners would then value own cultural heritages attached to obtaining valued experience in English language [8].
As an operational method to inspire active learning, for communication skills joined mutually with critical thinking, there is a need to encourage group work among learners [9]. On the other side, literature reveals that the current situation across all environments due to the COVID-19 regulations has brought about some negative effects resulting in stress from loss of peer interaction with regard to academic content as learners are no longer denied access to practice the so-called previously known normality of either sitting as groups or as pairs in a classroom setting, as a way of responding to the constraints of social distancing observance [7, 10]. This current state of affairs is declared similar to the period when there was once some disturbance in the schooling mode of behavior. There emerged an influenza first perceived in the United States, then later swiftly blew out across the entire countries of the world. As reported by the public health schools in such communities had to be closed down due to the influenza pandemic [11]. The schooling situation or practices by then were declared to have slightly changed as all inhabitants were expected to give full observance of the prescribed instructions by the then governmental officials.
Furthermore, as learners actively engage in group work, they obtain chances to express own opinions and ideas. As deliberations reach climax within a specific group of learners, critical thinking and robust discussion are also improved [12]. When learners’ critical thinking and engagement skills are improved, problem-solving is then enhanced, together with improved communication skills, consequently leading to an enriched cultural awareness [13]. Such improved skills would be eminent as learners would have learnt to listen at others’ opinions, then providing feedback. As this entire exercise is carried out, one would notice that learners forming a single group originate from dissimilar linguistic constituencies, different backgrounds, diverse cultures yet with varying learning styles, as such, at their early ages, learners then learn to have respect for each unique individual.
This manuscript is strengthened by Guskey’s model of teacher change [14]. A model of teacher change has been used for this investigation pertaining to changes currently championing the education system, as brought about by the COVID-19 etiquettes that need to be observed by all individuals around the country [15]. The framework further portrays ecological changes in consideration of the attitudes and beliefs toward teaching and learning, as is the case in the current schooling situation. Previously, teachers strongly believed that for an operational and functional language development in learners, better results used to be eminent when learners were grouped, yet the current situation has resulted on learner groupings being disbanded.
With respect to the main objective of this chapter, authors opine that for learners to comprehend any text with understanding, there is a dire requirement for a combined practice between the text itself and learners brainstorming as a group. To uplift and motivate this notion, language teachers are therefore anticipated as the ones to constantly allocate reading tasks to learners in the form of groups, irrespective of whether during the normal classroom environment, or for tasks assigned as take-home activities. If English language teachers would embark in this practice, language proficiency among learners would surely be enhanced as perceived by the authors [16]. Teachers therefore are regarded as the core recipients to ensure language enhancement in learners, as suggested by the theory underpinning this manuscript [14]. Innovative reading skills, ease at comprehending with text, and upgraded language skills would then emerge, therefore leading to academic excellence as the greatest percentage of the subjects buttressing the curriculum in the schools investigated are offered in the English medium.
For the purposes of this investigation, the authors followed a qualitative approach entrenched by a case study design. This is a research approach applied for generating an in-depth understanding for some compound issues affecting real-life situations. Authors used this type of design in order to have an understanding of recent social distancing trajectories affecting the previous normal running of schools [17]. Truths pertaining human behavior as authors studied the real-world circumstances that unfolded were put together [18]. An inclusive understanding pertaining to teacher perspectives on language development on the view that grouping of learners was no longer a practice, henceforth social distancing code of practice, was followed. For the context of this study, investigation was based on administering semistructured interviews to 10 purposefully selected teachers from three different primary schools in one district of the Eastern Cape Province in South Africa [19, 20]. Authors decided to embark on selecting participants in a purposive manner as this sampling technique allows researchers to rely on own judgment when nominating population members to participate. Henceforth, we decided to identify teachers from the surrounding locations where high COVID-19 death tolls had been reported by statistics [11]. Further than that, purposive sampling was a method that suited us well, hence the limited number of our participants who served as primary data sources by virtue of the case study designed ingraining this investigation. Participants nominated were teachers who offered English language as a medium reinforcing the utmost percentage of subjects enrolled in these particular schools.
As perceived by research, semistructured interviews as a data-collection instrument permitted the authors full engagement with all participants, more so that chances to explore more on crucial emerging themes seemed eminent [21]. Open-ended interview questions revolved around viewpoints of teachers on the subject of learner proficiency reading levels as directed by the abolishing of engaging on reading as groups, despite the previously reported improved readership in learners when such reading exercises used to be tackled in daily learner groupings. Despite the interview schedule containing open-ended questions, authors were at liberty to throw follow-up questions in instances where further clarities were deemed necessary. As a way of observing the current social distancing procedures, as well as avoiding grouping all participants in one common venue, interviews were conducted in a one-on-one fashion. Authors arranged meetings for each single participant at a single time. The interaction or engagements between the authors and participants started in September 2021 and at a later stage got terminated beginning December 2021 as both the interviewers and the interviewees became entangled in the processes of administering examinations in their varying work stations. As the interview schedule was administered, authors took some recordings, which were later replayed again and again. These recordings were taken in a different number of visits and days, for an interval ranging between 15 and 20 minutes for each individual participant. This method helped authors to be able to transcribe all responses from all participants, avoiding not to disregard any single response. Similar or relevant responses were grouped together and thereby coded by the authors as a way of formulating themes [17, 18, 19, 20, 21, 22].
There are two themes that emerged during data analysis from an argument of findings for this investigation [22]. In consideration of reading proficiency levels, it emerged that reading is affected by disbanded learner groupings due to the COVID-19 pandemic era code of practice. The second finding outlined relates to learner attitudes resulting in feeling isolated from their peers, and yet this is proving to somehow influence language development intertwined with learner achievement.
Among the group of participants, one teacher reported own observance on proficiency levels in reading among learners since in the classroom setting, learner groupings had no longer become the talk of the schooling environment:
It was divulged that the majority of learners felt isolated from their peers. Henceforth, the current COVID-19 social distancing restrictions pertaining to the seating logic of one learner seated in a stipulated distance away from the other, they no longer had opportunities to either exchange ideas or share information as they used to when seated as groups.
In relation to this encounter, one participant argued that:
Pertaining to reading proficiency levels, a key finding was a noted deterioration in reading progress among learners. Teachers offering English language as a subject debated that motivation within learners as groups no longer exists, actually, it has then been compromised as each learner had to battle or struggle on comprehending the text all alone, this somehow displaying a sudden lack of collegiality among learners registered for the same subject. This situation was even made worse by the current situation that existed when learners were at their cultural or rather home backgrounds. Learners had reported to respective teachers that isolation also roams in their living environments to such an extent that even if one had a neighbor with whom they are enrolled for the same grade, phase, or subject, parents denied their children access to visit others for purposes of information sharing sessions [23]. As authors of this manuscript, we really feel pity for the cohort of learners experiencing difficulties in comprehending with texts. Actually, this then becomes a call for language teachers to identify alternative strategies that would curb the situation of learners who feel isolated and left alone, as this might lead to implications of increased learner-dropout rate as well as lowered progression levels. On the other side, a reading nation is a wealthy nation, we all need to engage with written texts in order to be an economically balanced country.
To curb the situation, learners need to be motivated so as to be able to adapt in the unfamiliar systems of self-independency. Motivation is known for its importance especially in learning an unfamiliar language, in this instance this being an English language. Motivated learners have since been noted of achieving their goals, while on the other hand those with lack of motivation become victims of not obtaining the intended academic achievement. Nurtured motivation has been identified to lead higher levels of language competence. It therefore lies with English language teachers that as learners are held in situations of no longer vibrantly engaging with group members in the classroom environment, learners be encouraged and driven toward attaining short-term goals such as reading and writing, by so doing, they would improve in language proficiencies. Dissolution of learner groupings is perceived by learners as not supportive toward language learning. With limited collaboration, some learners could undergo stress disorders or related sicknesses [6, 7, 8, 9, 10].
Furthermore, as collaborative learning has proved to yield good results, teachers are then advised to let learners learn as either pairs or groups, even if the seating plan makes learners to be scattered from each other [24]. This method of learning collaboratively has been proved by other writers to have some advantages as research argues that in group work learners have an opportunity to learn from each other as they can better unpack some ideas clearer to respective classmates, as compared with how a teacher would have tackled it, this at times resulting from that some learners have an introvert attitude, as such become reluctant to seek assistance from their teachers [25].
From the collected data, it also emerged that the newly designed seating plan for learners to be positioned apart from their peers seemed to have some adverse impacts on learning, and specifically for the purposes of this investigation, isolation led to attitudes of neglect, this having an influence on language development [26]. The current seating plan in the schooling environment is attached with compliance of COVID-19 regulations on social distancing as prescribed by the South African government. Elements of anxiety in learners revolve around logistics encounters with regard to loneliness, discomposure, and loss of peer interaction [27]. To the authors’ perspective, these critical aspects are likely to have an influence on academic content and uncertainty in learner progression. Teachers also reported that learners whose comprehension levels were not of the expected average normally raised concerns that the current seating plan causes lots of stress, likely to impact on their development in learning.
On the other side, teachers also reported their concern regarding learner isolation as this might impact on emotional and social learning [28]. Proficiency gaps in reading abilities were noted by language teachers to have erupted ever since the innovations on the classroom seating plans, in so much that isolation even from friends and family in general, have normally resulted into an unhealthy social learning environment. This finding is in line with the views that for a task to be considered as outcomes-based, learners are expected to cultivate some links in between the content learnt and the encompassing learning styles thereof. Moreover, as learners comprehend and intermingle in the target language that is being learnt, there seems to be a crucial need for them to interact and communicate among themselves for easy access to acquire the logistics of the new and the unacquainted language. Engaging in such a strategy is likely to rebuild self-confidence, this leading to improved language proficiency levels [29]. For satisfactory progress, learning in schools needs to be a process administered through social relationships, including oneself, life, as well as collaborating with others through unanimous decision-making [30, 31]. By so doing, the school then becomes a family because of the supportive networking by both teachers and groups of learners. For such networking to be lost, it then really becomes a greatest concern ever. As the authors of this manuscript, we therefore opine for paramount importance that language teachers devise the necessary strategies aimed toward improved language proficiency with revised approaches to help rebuild the lost self-intrinsic inspiration within learners as swept away by isolation logistics.
The fundamental aim of this chapter was to measure the extent to which terminated learner groupings as a way of responding to the COVID-19 social distancing logistics had any influence on language enhancement. Importance of this investigation is reaffirmed as all the underlying discussions for this article have been proven to be aligned with the model of teacher change [14]. An examination of disbanded learner groupings led to the key finding outlining that indeed group work yields best results in relation to reading proficiency in leaners. From the data analyzed, it has become eminent to note that restricted groupings of learners in the current schooling situation seem to have an effect of redundancy toward a healthy reading culture. As perceived by the authors of this chapter, a nation with restricted or deprived culture of reading is tantamount to a vehicle expected to be in motion, yet fully loaded with a dead engine. Findings of this investigation therefore imply that despite the restrictions to group learners in classroom settings, language teachers are faced with a huge task to motivate the young, yet highlighting to them that with time they need to develop responsive attitudes with that sense of individual drive toward their learning, as the current state of affairs has led to all scholars being held up in the predicament of self-studies, of which no one had ever anticipated. Henceforth, authors recommend that managerial implications of this investigation be vested on the policymakers to redesign functional policies that would act as alternatives into restoring worthwhile sitting plans, yet, rebuilding that sense of inner ambiguity among learners no longer able to collaborate with peers as was in the previously disbanded learner groupings.
First and foremost, let me appreciate and thank the Almighty God for the strength and wisdom. Without His blessings, I doubt if we would have courage to successfully write this manuscript.
To write a book chapter is really hard work than I ever imagined, yet rewarding because as I continue embarking on the process of writing, my research skills coupled with academic writing logistics are sharpened day by day. This chapter encompasses to measure whether disbanding learner groupings as per the social distancing protocols brought about by COVID-19 restrictions has any significant impact on language enhancement.
I would be making a mistake not to acknowledge the amazing obligation that I owe toward researchers who encouraged me on manuscript writing. For this manuscript to be written in completion, an immense amount of work was done and would not have happened without an inspiration by a number of compassionate researchers whom I collaborated with, inclusive of:
Dr. Nomxolisi Mtsi, who was the first person to inspire me on research writing. As I narrated to her that my life situation had its ups and downs, she just told me that there was always a way out for whatever situation experienced. This academic was the one who whispered out loud in my ears that I need to start focusing on research writing. I can assume in me she sensed a hungry academic that needed some inspiration to grow. She went an extra mile to introduce me to Dr. Thandiswa Mpiti, with whom we are in the same field of research: languages. I am so grateful to have networked with such an academic, engaging on research writing, sharing experiences, and stimulating one another.
I cannot turn a blind eye on this one. To Dr. Shakespeare Chiphambo, no matter how the awkward timing would be, he is always eager to read through my drafts and offer whatever form of assistance I require from him in relation to manuscript writing.
I am ceaselessly appreciative to my mentor: Professor Bongani Bantwini, my managers at work: Professor Nolutho Diko and Mrs. Nondwe Mtshatsha. These seasoned academics would always and forever encourage me to make it a priority that I prioritize on manuscript writing to be considered as fully blown in academia. My mentor would always go an extra mile to read through my drafts.
Without proficiencies, collaboration, and support from my colleague at work, Dr. Ntando Elliot Mpahla, the research expertise on manuscript writing, would not have been to this level.
To all the researchers who would preach into my ears that to be regarded as a real academic one has to embark on publishing, thank you so much for inspiring more authors to have courage to convert their ideas to becoming stories. It is because of such inspiring comments that I have obtained some growth opportunities.
For the publication of this manuscript, I wish to extend my sincere gratitude to the Walter Sisulu Research Directorate for offering funding toward our publications. This stimulates and encourages us as researchers to have a maintained zeal toward the project as academic writers.
Writing a chapter about real-life experiences encountered in the workplace during the processes of teaching and learning is indeed a bizarre process, but through the ongoing support of the colleagues in the same field of work, there was continued motivation and inspiration to maintain the passion of bringing all our stories to life.
A very special word of thanks goes to my family. My kids, Yonela, Tina, and Zenazi, for supporting me without complaining even at times when I gave them less attention than they expected. My nephews and nieces, Odwa, Ongeziwe, Lisolethu, Kungawo, Amyoli, and Minathi, for exercising patience when I took longer to assist them with their studies while I was still hooked up in this little piece of writing. Their level of understanding is well applauded. My brother, Campbell, and sisters, Xoliswa and Hombakazi, for always encouraging me in whatever endeavor intending to make my life a better one. My mom, Vuyiswa, who would always and forever urge all her kids to prioritize with engaging in furthering their studies for being successful and prominent citizens. Lastly, my debt goes to my late dad, Erick Vuyisilet, who always dreamt big about the level of education for his children.
Conclusions to this study have been sharpened by contributions of our participants. For the time they excellently dedicated in engaging in this investigation, they are highly acknowledged.
To what extent is social distancing in relation to learner attitudes versus isolation affecting language development?
What role does social distancing play with respect to learner groupings on reading proficiency levels?
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Modification and Application",isOpenForSubmission:!1,hash:"af8042e24c2f68bb66b0633502754ebd",slug:"alkaloids-alternatives-in-synthesis-modification-and-application",bookSignature:"Vasil Georgiev and Atanas Pavlov",coverURL:"https://cdn.intechopen.com/books/images_new/5681.jpg",editedByType:"Edited by",editors:[{id:"165414",title:"Dr.",name:"Vasil",middleName:null,surname:"Georgiev",slug:"vasil-georgiev",fullName:"Vasil Georgiev"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"4785",title:"Cellulose",subtitle:"Fundamental Aspects and Current Trends",isOpenForSubmission:!1,hash:"e1dcc6cb2bc929641d711f320ac52970",slug:"cellulose-fundamental-aspects-and-current-trends",bookSignature:"Matheus Poletto and Heitor Luiz Ornaghi Junior",coverURL:"https://cdn.intechopen.com/books/images_new/4785.jpg",editedByType:"Edited 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Properties",slug:"crystalline-nanocellulose-preparation-modification-and-properties",totalDownloads:10598,totalCrossrefCites:54,totalDimensionsCites:130,abstract:"Cellulose is a linear biopolymer found naturally in plant cells such as wood and cotton. It is the worlds most abundant polymer in nature and possesses properties such as good biocompatibility, low cost, low density, high strength, and good mechanical properties. By mechanical or chemical treatment, the cellulose fibers can be converted into cellulose nanofibers (CNFs) or cellulose nanocrystals (CNCs) that possess outstanding properties compared with the original cellulosic fiber but also when compared with other materials normally used as reinforcements in composite materials such as Kevlar or steel wires. This review will describe the nanocellulose materials preparation techniques and cellulose sources, chemical modification both on the crystalline surface and during hydrolysis and its many properties and its use in biocomposite materials. Nanocellulose in its different forms shows an increasing interest in application areas such as packaging, paper and paperboard, food industry, medical and hygiene products, paints, cosmetics, and optical sensors",book:{id:"4785",slug:"cellulose-fundamental-aspects-and-current-trends",title:"Cellulose",fullTitle:"Cellulose - Fundamental Aspects and Current Trends"},signatures:"Mikaela Börjesson and Gunnar Westman",authors:[{id:"142372",title:"Prof.",name:"Gunnar",middleName:null,surname:"Westman",slug:"gunnar-westman",fullName:"Gunnar Westman"},{id:"174946",title:"MSc.",name:"Mikaela",middleName:null,surname:"Borjesson",slug:"mikaela-borjesson",fullName:"Mikaela Borjesson"}]},{id:"45613",doi:"10.5772/50452",title:"Structural Characteristics and Thermal Properties of Native Cellulose",slug:"structural-characteristics-and-thermal-properties-of-native-cellulose",totalDownloads:6739,totalCrossrefCites:50,totalDimensionsCites:126,abstract:null,book:{id:"2326",slug:"cellulose-fundamental-aspects",title:"Cellulose",fullTitle:"Cellulose - Fundamental Aspects"},signatures:"Matheus Poletto, Vinícios Pistor and Ademir J. Zattera",authors:[{id:"140017",title:"Dr.",name:"Matheus",middleName:null,surname:"Poletto",slug:"matheus-poletto",fullName:"Matheus Poletto"},{id:"142401",title:"Mr.",name:"Vinícios",middleName:null,surname:"Pistor",slug:"vinicios-pistor",fullName:"Vinícios Pistor"},{id:"142402",title:"Prof.",name:"Ademir José",middleName:null,surname:"Zattera",slug:"ademir-jose-zattera",fullName:"Ademir José Zattera"}]},{id:"40586",doi:"10.5772/50561",title:"Polysaccharide-Protein Interactions and Their Relevance in Food Colloids",slug:"polysaccharide-protein-interactions-and-their-relevance-in-food-colloids",totalDownloads:5913,totalCrossrefCites:13,totalDimensionsCites:87,abstract:null,book:{id:"2572",slug:"the-complex-world-of-polysaccharides",title:"The Complex World of Polysaccharides",fullTitle:"The Complex World of Polysaccharides"},signatures:"Amit K. Ghosh and Prasun Bandyopadhyay",authors:[{id:"137018",title:"Mr.",name:"Amit",middleName:null,surname:"Ghosh",slug:"amit-ghosh",fullName:"Amit Ghosh"},{id:"139509",title:"Dr.",name:"Prasun",middleName:null,surname:"Bandyopadhyay",slug:"prasun-bandyopadhyay",fullName:"Prasun Bandyopadhyay"}]},{id:"49195",doi:"10.5772/61334",title:"Current Trends in the Production of Cellulose Nanoparticles and Nanocomposites for Biomedical Applications",slug:"current-trends-in-the-production-of-cellulose-nanoparticles-and-nanocomposites-for-biomedical-applic",totalDownloads:7506,totalCrossrefCites:30,totalDimensionsCites:75,abstract:"The goal of this chapter is to review the most recent trends to produce cellulose nanoparticles and nanocomposites with biomedical applications. These particles could be named as bacterial cellulose, cellulose nanofibers, and cellulose nanocrystals. The production of these nanoparticles with diameters below 100 nm is challenging because of the strong agglomeration tendency which occur upon drying aqueous cellulose suspensions or during the compounding process with hydrophobic polymers. Typically, the physical and mechanical properties of these nanoparticles depend on the source of cellulose and the extraction process employed. Cellulose nanoparticles are obtained by mechanical, chemical, or enzymatic process treatments to open the structure of the cellulose source and facilitate accessibility to its microstructure. Usually, a combination of these processes makes the extraction more efficient.",book:{id:"4785",slug:"cellulose-fundamental-aspects-and-current-trends",title:"Cellulose",fullTitle:"Cellulose - Fundamental Aspects and Current Trends"},signatures:"John Rojas, Mauricio Bedoya and Yhors Ciro",authors:[{id:"143552",title:"Dr",name:null,middleName:null,surname:"John Rojas",slug:"john-rojas",fullName:"John Rojas"}]}],mostDownloadedChaptersLast30Days:[{id:"45635",title:"Application of Cellulose and Cellulose Derivatives in Pharmaceutical Industries",slug:"application-of-cellulose-and-cellulose-derivatives-in-pharmaceutical-industries",totalDownloads:10348,totalCrossrefCites:60,totalDimensionsCites:138,abstract:null,book:{id:"3173",slug:"cellulose-medical-pharmaceutical-and-electronic-applications",title:"Cellulose",fullTitle:"Cellulose - Medical, Pharmaceutical and Electronic Applications"},signatures:"Javad Shokri and Khosro Adibkia",authors:[{id:"140056",title:"Prof.",name:"Javad",middleName:null,surname:"Shokri",slug:"javad-shokri",fullName:"Javad Shokri"}]},{id:"61452",title:"Pyridine: A Useful Ligand in Transition Metal Complexes",slug:"pyridine-a-useful-ligand-in-transition-metal-complexes",totalDownloads:3505,totalCrossrefCites:14,totalDimensionsCites:25,abstract:"Pyridine (C5H5N) is being the simplest six-membered heterocycles, closely resembles its structure to benzene. The “N” in benzene ring has its high electronegativity influence on resonance environment and produces markedly different chemistry from its carbon analog. The presence of nitrogen and its lone pair in an aromatic environment makes pyridine a unique substance in chemistry. The sp2 lone pair orbital of “N,” directed outward the ring skeleton, is well directed to have overlap with vacant metal orbital in producing an σ bonding interaction. This causes pyridine to be a ligand and has been utilized with all transition metals in producing the array of metal complexes. A rich literature of metal complexes is now available with pyridine and its derivatives. Innumerable complexes have been synthesized with academic as well as industrial importance. To shed a light on ligating capability of pyridine, transition metal complexes with pyridine, and its derivative is presented in this chapter.",book:{id:"6574",slug:"pyridine",title:"Pyridine",fullTitle:"Pyridine"},signatures:"Satyanarayan Pal",authors:[{id:"230561",title:"Dr.",name:"Satyanarayan",middleName:null,surname:"Pal",slug:"satyanarayan-pal",fullName:"Satyanarayan Pal"}]},{id:"39461",title:"The Role of Glycosylation in Receptor Signaling",slug:"the-role-of-glycosylation-in-receptor-signaling",totalDownloads:5716,totalCrossrefCites:2,totalDimensionsCites:10,abstract:null,book:{id:"2540",slug:"glycosylation",title:"Glycosylation",fullTitle:"Glycosylation"},signatures:"Brian J. Arey",authors:[{id:"147494",title:"Dr.",name:"Brian",middleName:null,surname:"Arey",slug:"brian-arey",fullName:"Brian Arey"}]},{id:"68066",title:"The Oxygen-Containing Fused Heterocyclic Compounds",slug:"the-oxygen-containing-fused-heterocyclic-compounds",totalDownloads:1136,totalCrossrefCites:1,totalDimensionsCites:1,abstract:"The oxygen-containing heterocycles are an important class of compounds in organic chemistry. These compounds are used as drugs (coumarin and oxazole), solvent (tetrahydrofuran), flavors, and fragrances (lactones). The fusion of aromatic ring to the oxygen-heterocycle will change the electron density; thereby, the physical/chemical/biological properties will alter. Also, the preparation of these fused molecules will require a different strategy/method/reaction condition. The topics covered in this chapter are the general synthetic methods and uses of fused heterocyclic compounds containing oxygen as a heteroatom. The derivatization of the primary scaffold is excluded from this chapter. Some of the fused compounds are coumarin (benzopyrans) and piclozotan (benzoxazepines).",book:{id:"8410",slug:"heterocycles-synthesis-and-biological-activities",title:"Heterocycles",fullTitle:"Heterocycles - Synthesis and Biological Activities"},signatures:"Hillemane Venkatachalam and Nanjangud Venkatesh Anil Kumar",authors:[{id:"270936",title:"Prof.",name:"N V",middleName:null,surname:"Anil Kumar",slug:"n-v-anil-kumar",fullName:"N V Anil Kumar"},{id:"280725",title:"Dr.",name:"Hillemane",middleName:null,surname:"Venkatachalam",slug:"hillemane-venkatachalam",fullName:"Hillemane Venkatachalam"}]},{id:"70509",title:"Amidoxime Derivatives with Local Anesthetic, Antitubercular, and Antidiabetic Activity",slug:"amidoxime-derivatives-with-local-anesthetic-antitubercular-and-antidiabetic-activity",totalDownloads:760,totalCrossrefCites:1,totalDimensionsCites:1,abstract:"Оur task in the field of new derivatives of amidoximes was the elaboration for new medication with increased activity and lower toxicity than medications used in practice. Here are the results of the search for new painkillers and antitubercular and antidiabetic drugs in the class of amidoxime derivatives. Nitrous derivatives of α-chloro-α-isonitrosoacetone, O-aroyl-β-aminopropioamidoximes, and 3-[β-(piperidine-1-yl)]ethyl-5-aryl-1,2,4-oxadiazoles were tested for conduction, infiltration, and terminal anesthesia. Among them hit compounds were discovered. The search for new anti-TB drugs is executed in the world. Salts and bases of O-aroylation products of β-(thiomorpholin-1-yl) and β-(4-methylpiperazin-1-yl)propioamidoximes during in vitro antitubercular screening for DS, DR, and MDR strains of M. tuberculosis manifest themselves as highly active competitive compounds. In the series of the derivatives of β-aminopropioamidoximes, a search for new antidiabetic drugs was done. The compounds with pronounced antidiabetic properties were revealed. The obtained data of the most promising samples with a preliminary assessment of their average toxic dose in animals can be used in further in vivo testing of infiltration anesthesia conditions, of antidiabetic properties, and at the development of doses and new treatment regimens for TB.",book:{id:"8410",slug:"heterocycles-synthesis-and-biological-activities",title:"Heterocycles",fullTitle:"Heterocycles - Synthesis and Biological Activities"},signatures:"Lyudmila Kayukova, Umirzak Jussipbekov and Kaldybay Praliyev",authors:[{id:"308490",title:"Prof.",name:"Lyudmila",middleName:null,surname:"Kayukova",slug:"lyudmila-kayukova",fullName:"Lyudmila Kayukova"},{id:"311781",title:"Prof.",name:"Kaldybay",middleName:null,surname:"Praliyev",slug:"kaldybay-praliyev",fullName:"Kaldybay Praliyev"}]}],onlineFirstChaptersFilter:{topicId:"494",limit:6,offset:0},onlineFirstChaptersCollection:[],onlineFirstChaptersTotal:0},preDownload:{success:null,errors:{}},subscriptionForm:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[],offset:8,limit:8,total:0},allSeries:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:9,numberOfPublishedChapters:90,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:107,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:33,numberOfPublishedChapters:330,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:14,numberOfPublishedChapters:145,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:9,numberOfPublishedChapters:140,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!0},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:123,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:11,numberOfPublishedChapters:112,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:22,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2753-894X",doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:11,numberOfOpenTopics:1,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!0},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:5,numberOfUpcomingTopics:0,issn:"2753-6580",doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],testimonialsList:[{id:"6",text:"It is great to work with the IntechOpen to produce a worthwhile collection of research that also becomes a great educational resource and guide for future research endeavors.",author:{id:"259298",name:"Edward",surname:"Narayan",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259298/images/system/259298.jpeg",slug:"edward-narayan",institution:{id:"3",name:"University of Queensland",country:{id:null,name:"Australia"}}}},{id:"13",text:"The collaboration with and support of the technical staff of IntechOpen is fantastic. The whole process of submitting an article and editing of the submitted article goes extremely smooth and fast, the number of reads and downloads of chapters is high, and the contributions are also frequently cited.",author:{id:"55578",name:"Antonio",surname:"Jurado-Navas",institutionString:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRisIQAS/Profile_Picture_1626166543950",slug:"antonio-jurado-navas",institution:{id:"720",name:"University of Malaga",country:{id:null,name:"Spain"}}}}]},series:{item:{id:"14",title:"Artificial Intelligence",doi:"10.5772/intechopen.79920",issn:"2633-1403",scope:"Artificial Intelligence (AI) is a rapidly developing multidisciplinary research area that aims to solve increasingly complex problems. In today's highly integrated world, AI promises to become a robust and powerful means for obtaining solutions to previously unsolvable problems. This Series is intended for researchers and students alike interested in this fascinating field and its many applications.",coverUrl:"https://cdn.intechopen.com/series/covers/14.jpg",latestPublicationDate:"July 5th, 2022",hasOnlineFirst:!0,numberOfPublishedBooks:9,editor:{id:"218714",title:"Prof.",name:"Andries",middleName:null,surname:"Engelbrecht",slug:"andries-engelbrecht",fullName:"Andries Engelbrecht",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRNR8QAO/Profile_Picture_1622640468300",biography:"Andries Engelbrecht received the Masters and PhD degrees in Computer Science from the University of Stellenbosch, South Africa, in 1994 and 1999 respectively. He is currently appointed as the Voigt Chair in Data Science in the Department of Industrial Engineering, with a joint appointment as Professor in the Computer Science Division, Stellenbosch University. Prior to his appointment at Stellenbosch University, he has been at the University of Pretoria, Department of Computer Science (1998-2018), where he was appointed as South Africa Research Chair in Artifical Intelligence (2007-2018), the head of the Department of Computer Science (2008-2017), and Director of the Institute for Big Data and Data Science (2017-2018). In addition to a number of research articles, he has written two books, Computational Intelligence: An Introduction and Fundamentals of Computational Swarm Intelligence.",institutionString:null,institution:{name:"Stellenbosch University",institutionURL:null,country:{name:"South Africa"}}},editorTwo:null,editorThree:null},subseries:{paginationCount:6,paginationItems:[{id:"22",title:"Applied Intelligence",coverUrl:"https://cdn.intechopen.com/series_topics/covers/22.jpg",isOpenForSubmission:!0,annualVolume:11418,editor:{id:"27170",title:"Prof.",name:"Carlos",middleName:"M.",surname:"Travieso-Gonzalez",slug:"carlos-travieso-gonzalez",fullName:"Carlos Travieso-Gonzalez",profilePictureURL:"https://mts.intechopen.com/storage/users/27170/images/system/27170.jpeg",biography:"Carlos M. Travieso-González received his MSc degree in Telecommunication Engineering at Polytechnic University of Catalonia (UPC), Spain in 1997, and his Ph.D. degree in 2002 at the University of Las Palmas de Gran Canaria (ULPGC-Spain). He is a full professor of signal processing and pattern recognition and is head of the Signals and Communications Department at ULPGC, teaching from 2001 on subjects on signal processing and learning theory. His research lines are biometrics, biomedical signals and images, data mining, classification system, signal and image processing, machine learning, and environmental intelligence. He has researched in 52 international and Spanish research projects, some of them as head researcher. He is co-author of 4 books, co-editor of 27 proceedings books, guest editor for 8 JCR-ISI international journals, and up to 24 book chapters. He has over 450 papers published in international journals and conferences (81 of them indexed on JCR – ISI - Web of Science). He has published seven patents in the Spanish Patent and Trademark Office. He has been a supervisor on 8 Ph.D. theses (11 more are under supervision), and 130 master theses. He is the founder of The IEEE IWOBI conference series and the president of its Steering Committee, as well as the founder of both the InnoEducaTIC and APPIS conference series. He is an evaluator of project proposals for the European Union (H2020), Medical Research Council (MRC, UK), Spanish Government (ANECA, Spain), Research National Agency (ANR, France), DAAD (Germany), Argentinian Government, and the Colombian Institutions. He has been a reviewer in different indexed international journals (<70) and conferences (<250) since 2001. He has been a member of the IASTED Technical Committee on Image Processing from 2007 and a member of the IASTED Technical Committee on Artificial Intelligence and Expert Systems from 2011. \n\nHe has held the general chair position for the following: ACM-APPIS (2020, 2021), IEEE-IWOBI (2019, 2020 and 2020), A PPIS (2018, 2019), IEEE-IWOBI (2014, 2015, 2017, 2018), InnoEducaTIC (2014, 2017), IEEE-INES (2013), NoLISP (2011), JRBP (2012), and IEEE-ICCST (2005)\n\nHe is an associate editor of the Computational Intelligence and Neuroscience Journal (Hindawi – Q2 JCR-ISI). He was vice dean from 2004 to 2010 in the Higher Technical School of Telecommunication Engineers at ULPGC and the vice dean of Graduate and Postgraduate Studies from March 2013 to November 2017. He won the “Catedra Telefonica” Awards in Modality of Knowledge Transfer, 2017, 2018, and 2019 editions, and awards in Modality of COVID Research in 2020.\n\nPublic References:\nResearcher ID http://www.researcherid.com/rid/N-5967-2014\nORCID https://orcid.org/0000-0002-4621-2768 \nScopus Author ID https://www.scopus.com/authid/detail.uri?authorId=6602376272\nScholar Google https://scholar.google.es/citations?user=G1ks9nIAAAAJ&hl=en \nResearchGate https://www.researchgate.net/profile/Carlos_Travieso",institutionString:null,institution:{name:"University of Las Palmas de Gran Canaria",institutionURL:null,country:{name:"Spain"}}},editorTwo:null,editorThree:null},{id:"23",title:"Computational Neuroscience",coverUrl:"https://cdn.intechopen.com/series_topics/covers/23.jpg",isOpenForSubmission:!0,annualVolume:11419,editor:{id:"14004",title:"Dr.",name:"Magnus",middleName:null,surname:"Johnsson",slug:"magnus-johnsson",fullName:"Magnus Johnsson",profilePictureURL:"https://mts.intechopen.com/storage/users/14004/images/system/14004.png",biography:"Dr Magnus Johnsson is a cross-disciplinary scientist, lecturer, scientific editor and AI/machine learning consultant from Sweden. \n\nHe is currently at Malmö University in Sweden, but also held positions at Lund University in Sweden and at Moscow Engineering Physics Institute. \nHe holds editorial positions at several international scientific journals and has served as a scientific editor for books and special journal issues. \nHis research interests are wide and include, but are not limited to, autonomous systems, computer modeling, artificial neural networks, artificial intelligence, cognitive neuroscience, cognitive robotics, cognitive architectures, cognitive aids and the philosophy of mind. \n\nDr. Johnsson has experience from working in the industry and he has a keen interest in the application of neural networks and artificial intelligence to fields like industry, finance, and medicine. \n\nWeb page: www.magnusjohnsson.se",institutionString:null,institution:{name:"Malmö University",institutionURL:null,country:{name:"Sweden"}}},editorTwo:null,editorThree:null},{id:"24",title:"Computer Vision",coverUrl:"https://cdn.intechopen.com/series_topics/covers/24.jpg",isOpenForSubmission:!0,annualVolume:11420,editor:{id:"294154",title:"Prof.",name:"George",middleName:null,surname:"Papakostas",slug:"george-papakostas",fullName:"George Papakostas",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002hYaGbQAK/Profile_Picture_1624519712088",biography:"George A. Papakostas has received a diploma in Electrical and Computer Engineering in 1999 and the M.Sc. and Ph.D. degrees in Electrical and Computer Engineering in 2002 and 2007, respectively, from the Democritus University of Thrace (DUTH), Greece. Dr. Papakostas serves as a Tenured Full Professor at the Department of Computer Science, International Hellenic University, Greece. Dr. Papakostas has 10 years of experience in large-scale systems design as a senior software engineer and technical manager, and 20 years of research experience in the field of Artificial Intelligence. Currently, he is the Head of the “Visual Computing” division of HUman-MAchines INteraction Laboratory (HUMAIN-Lab) and the Director of the MPhil program “Advanced Technologies in Informatics and Computers” hosted by the Department of Computer Science, International Hellenic University. He has (co)authored more than 150 publications in indexed journals, international conferences and book chapters, 1 book (in Greek), 3 edited books, and 5 journal special issues. His publications have more than 2100 citations with h-index 27 (GoogleScholar). His research interests include computer/machine vision, machine learning, pattern recognition, computational intelligence. \nDr. Papakostas served as a reviewer in numerous journals, as a program\ncommittee member in international conferences and he is a member of the IAENG, MIR Labs, EUCogIII, INSTICC and the Technical Chamber of Greece (TEE).",institutionString:null,institution:{name:"International Hellenic University",institutionURL:null,country:{name:"Greece"}}},editorTwo:null,editorThree:null},{id:"25",title:"Evolutionary Computation",coverUrl:"https://cdn.intechopen.com/series_topics/covers/25.jpg",isOpenForSubmission:!0,annualVolume:11421,editor:{id:"136112",title:"Dr.",name:"Sebastian",middleName:null,surname:"Ventura Soto",slug:"sebastian-ventura-soto",fullName:"Sebastian Ventura Soto",profilePictureURL:"https://mts.intechopen.com/storage/users/136112/images/system/136112.png",biography:"Sebastian Ventura is a Spanish researcher, a full professor with the Department of Computer Science and Numerical Analysis, University of Córdoba. 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Recent Advances, New Perspectives and Applications",editors:[{id:"49813",title:"Dr.",name:"Javier",middleName:null,surname:"Del Ser",slug:"javier-del-ser",fullName:"Javier Del Ser",profilePictureURL:"https://mts.intechopen.com/storage/users/49813/images/system/49813.png",institutionString:"Tecnalia Research & Innovation",institution:{name:"Tecnalia",institutionURL:null,country:{name:"Spain"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"7723",title:"Artificial Intelligence",subtitle:"Applications in Medicine and Biology",coverURL:"https://cdn.intechopen.com/books/images_new/7723.jpg",slug:"artificial-intelligence-applications-in-medicine-and-biology",publishedDate:"July 31st 2019",editedByType:"Edited by",bookSignature:"Marco Antonio Aceves-Fernandez",hash:"a3852659e727f95c98c740ed98146011",volumeInSeries:1,fullTitle:"Artificial Intelligence - Applications in Medicine and Biology",editors:[{id:"24555",title:"Dr.",name:"Marco Antonio",middleName:null,surname:"Aceves Fernandez",slug:"marco-antonio-aceves-fernandez",fullName:"Marco Antonio Aceves Fernandez",profilePictureURL:"https://mts.intechopen.com/storage/users/24555/images/system/24555.jpg",institutionString:"Universidad Autonoma de Queretaro",institution:{name:"Autonomous University of Queretaro",institutionURL:null,country:{name:"Mexico"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null}]},subseriesFiltersForPublishedBooks:[{group:"subseries",caption:"Computational Neuroscience",value:23,count:1},{group:"subseries",caption:"Evolutionary Computation",value:25,count:1},{group:"subseries",caption:"Machine Learning and Data Mining",value:26,count:3},{group:"subseries",caption:"Applied Intelligence",value:22,count:4}],publicationYearFilters:[{group:"publicationYear",caption:"2022",value:2022,count:2},{group:"publicationYear",caption:"2021",value:2021,count:3},{group:"publicationYear",caption:"2020",value:2020,count:2},{group:"publicationYear",caption:"2019",value:2019,count:2}],authors:{paginationCount:148,paginationItems:[{id:"165328",title:"Dr.",name:"Vahid",middleName:null,surname:"Asadpour",slug:"vahid-asadpour",fullName:"Vahid Asadpour",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/165328/images/system/165328.jpg",biography:"Vahid Asadpour, MS, Ph.D., is currently with the Department of Research and Evaluation, Kaiser Permanente Southern California. He has both an MS and Ph.D. in Biomedical Engineering. He was previously a research scientist at the University of California Los Angeles (UCLA) and visiting professor and researcher at the University of North Dakota. He is currently working in artificial intelligence and its applications in medical signal processing. In addition, he is using digital signal processing in medical imaging and speech processing. Dr. Asadpour has developed brain-computer interfacing algorithms and has published books, book chapters, and several journal and conference papers in this field and other areas of intelligent signal processing. He has also designed medical devices, including a laser Doppler monitoring system.",institutionString:"Kaiser Permanente Southern California",institution:null},{id:"169608",title:"Prof.",name:"Marian",middleName:null,surname:"Găiceanu",slug:"marian-gaiceanu",fullName:"Marian Găiceanu",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/169608/images/system/169608.png",biography:"Prof. Dr. Marian Gaiceanu graduated from the Naval and Electrical Engineering Faculty, Dunarea de Jos University of Galati, Romania, in 1997. He received a Ph.D. (Magna Cum Laude) in Electrical Engineering in 2002. Since 2017, Dr. Gaiceanu has been a Ph.D. supervisor for students in Electrical Engineering. He has been employed at Dunarea de Jos University of Galati since 1996, where he is currently a professor. Dr. Gaiceanu is a member of the National Council for Attesting Titles, Diplomas and Certificates, an expert of the Executive Agency for Higher Education, Research Funding, and a member of the Senate of the Dunarea de Jos University of Galati. He has been the head of the Integrated Energy Conversion Systems and Advanced Control of Complex Processes Research Center, Romania, since 2016. He has conducted several projects in power converter systems for electrical drives, power quality, PEM and SOFC fuel cell power converters for utilities, electric vehicles, and marine applications with the Department of Regulation and Control, SIEI S.pA. (2002–2004) and the Polytechnic University of Turin, Italy (2002–2004, 2006–2007). He is a member of the Institute of Electrical and Electronics Engineers (IEEE) and cofounder-member of the IEEE Power Electronics Romanian Chapter. He is a guest editor at Energies and an academic book editor for IntechOpen. He is also a member of the editorial boards of the Journal of Electrical Engineering, Electronics, Control and Computer Science and Sustainability. Dr. Gaiceanu has been General Chairman of the IEEE International Symposium on Electrical and Electronics Engineering in the last six editions.",institutionString:'"Dunarea de Jos" University of Galati',institution:{name:'"Dunarea de Jos" University of Galati',country:{name:"Romania"}}},{id:"4519",title:"Prof.",name:"Jaydip",middleName:null,surname:"Sen",slug:"jaydip-sen",fullName:"Jaydip Sen",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/4519/images/system/4519.jpeg",biography:"Jaydip Sen is associated with Praxis Business School, Kolkata, India, as a professor in the Department of Data Science. His research areas include security and privacy issues in computing and communication, intrusion detection systems, machine learning, deep learning, and artificial intelligence in the financial domain. He has more than 200 publications in reputed international journals, refereed conference proceedings, and 20 book chapters in books published by internationally renowned publishing houses, such as Springer, CRC press, IGI Global, etc. Currently, he is serving on the editorial board of the prestigious journal Frontiers in Communications and Networks and in the technical program committees of a number of high-ranked international conferences organized by the IEEE, USA, and the ACM, USA. He has been listed among the top 2% of scientists in the world for the last three consecutive years, 2019 to 2021 as per studies conducted by the Stanford University, USA.",institutionString:"Praxis Business School",institution:null},{id:"320071",title:"Dr.",name:"Sidra",middleName:null,surname:"Mehtab",slug:"sidra-mehtab",fullName:"Sidra Mehtab",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00002v6KHoQAM/Profile_Picture_1584512086360",biography:"Sidra Mehtab has completed her BS with honors in Physics from Calcutta University, India in 2018. She has done MS in Data Science and Analytics from Maulana Abul Kalam Azad University of Technology (MAKAUT), Kolkata, India in 2020. Her research areas include Econometrics, Time Series Analysis, Machine Learning, Deep Learning, Artificial Intelligence, and Computer and Network Security with a particular focus on Cyber Security Analytics. Ms. Mehtab has published seven papers in international conferences and one of her papers has been accepted for publication in a reputable international journal. She has won the best paper awards in two prestigious international conferences – BAICONF 2019, and ICADCML 2021, organized in the Indian Institute of Management, Bangalore, India in December 2019, and SOA University, Bhubaneswar, India in January 2021. Besides, Ms. Mehtab has also published two book chapters in two books. Seven of her book chapters will be published in a volume shortly in 2021 by Cambridge Scholars’ Press, UK. Currently, she is working as the joint editor of two edited volumes on Time Series Analysis and Forecasting to be published in the first half of 2021 by an international house. Currently, she is working as a Data Scientist with an MNC in Delhi, India.",institutionString:"NSHM College of Management and Technology",institution:{name:"Association for Computing Machinery",country:{name:"United States of America"}}},{id:"226240",title:"Dr.",name:"Andri Irfan",middleName:null,surname:"Rifai",slug:"andri-irfan-rifai",fullName:"Andri Irfan Rifai",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/226240/images/7412_n.jpg",biography:"Andri IRFAN is a Senior Lecturer of Civil Engineering and Planning. He completed the PhD at the Universitas Indonesia & Universidade do Minho with Sandwich Program Scholarship from the Directorate General of Higher Education and LPDP scholarship. He has been teaching for more than 19 years and much active to applied his knowledge in the project construction in Indonesia. His research interest ranges from pavement management system to advanced data mining techniques for transportation engineering. He has published more than 50 papers in journals and 2 books.",institutionString:null,institution:{name:"Universitas Internasional Batam",country:{name:"Indonesia"}}},{id:"314576",title:"Dr.",name:"Ibai",middleName:null,surname:"Laña",slug:"ibai-lana",fullName:"Ibai Laña",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/314576/images/system/314576.jpg",biography:"Dr. Ibai Laña works at TECNALIA as a data analyst. He received his Ph.D. in Artificial Intelligence from the University of the Basque Country (UPV/EHU), Spain, in 2018. He is currently a senior researcher at TECNALIA. His research interests fall within the intersection of intelligent transportation systems, machine learning, traffic data analysis, and data science. He has dealt with urban traffic forecasting problems, applying machine learning models and evolutionary algorithms. He has experience in origin-destination matrix estimation or point of interest and trajectory detection. Working with large volumes of data has given him a good command of big data processing tools and NoSQL databases. He has also been a visiting scholar at the Knowledge Engineering and Discovery Research Institute, Auckland University of Technology.",institutionString:"TECNALIA Research & Innovation",institution:{name:"Tecnalia",country:{name:"Spain"}}},{id:"314575",title:"Dr.",name:"Jesus",middleName:null,surname:"L. Lobo",slug:"jesus-l.-lobo",fullName:"Jesus L. Lobo",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/314575/images/system/314575.png",biography:"Dr. Jesús López is currently based in Bilbao (Spain) working at TECNALIA as Artificial Intelligence Research Scientist. In most cases, a project idea or a new research line needs to be investigated to see if it is good enough to take into production or to focus on it. That is exactly what he does, diving into Machine Learning algorithms and technologies to help TECNALIA to decide whether something is great in theory or will actually impact on the product or processes of its projects. So, he is expert at framing experiments, developing hypotheses, and proving whether they’re true or not, in order to investigate fundamental problems with a longer time horizon. He is also able to design and develop PoCs and system prototypes in simulation. He has participated in several national and internacional R&D projects.\n\nAs another relevant part of his everyday research work, he usually publishes his findings in reputed scientific refereed journals and international conferences, occasionally acting as reviewer and Programme Commitee member. Concretely, since 2018 he has published 9 JCR (8 Q1) journal papers, 9 conference papers (e.g. ECML PKDD 2021), and he has co-edited a book. He is also active in popular science writing data science stories for reputed blogs (KDNuggets, TowardsDataScience, Naukas). Besides, he has recently embarked on mentoring programmes as mentor, and has also worked as data science trainer.",institutionString:"TECNALIA Research & Innovation",institution:{name:"Tecnalia",country:{name:"Spain"}}},{id:"103779",title:"Prof.",name:"Yalcin",middleName:null,surname:"Isler",slug:"yalcin-isler",fullName:"Yalcin Isler",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRyQ8QAK/Profile_Picture_1628834958734",biography:"Yalcin Isler (1971 - Burdur / Turkey) received the B.Sc. degree in the Department of Electrical and Electronics Engineering from Anadolu University, Eskisehir, Turkey, in 1993, the M.Sc. degree from the Department of Electronics and Communication Engineering, Suleyman Demirel University, Isparta, Turkey, in 1996, the Ph.D. degree from the Department of Electrical and Electronics Engineering, Dokuz Eylul University, Izmir, Turkey, in 2009, and the Competence of Associate Professorship from the Turkish Interuniversity Council in 2019.\n\nHe was Lecturer at Burdur Vocational School in Suleyman Demirel University (1993-2000, Burdur / Turkey), Software Engineer (2000-2002, Izmir / Turkey), Research Assistant in Bulent Ecevit University (2002-2003, Zonguldak / Turkey), Research Assistant in Dokuz Eylul University (2003-2010, Izmir / Turkey), Assistant Professor at the Department of Electrical and Electronics Engineering in Bulent Ecevit University (2010-2012, Zonguldak / Turkey), Assistant Professor at the Department of Biomedical Engineering in Izmir Katip Celebi University (2012-2019, Izmir / Turkey). He is an Associate Professor at the Department of Biomedical Engineering at Izmir Katip Celebi University, Izmir / Turkey, since 2019. In addition to academics, he has also founded Islerya Medical and Information Technologies Company, Izmir / Turkey, since 2017.\n\nHis main research interests cover biomedical signal processing, pattern recognition, medical device design, programming, and embedded systems. He has many scientific papers and participated in several projects in these study fields. He was an IEEE Student Member (2009-2011) and IEEE Member (2011-2014) and has been IEEE Senior Member since 2014.",institutionString:null,institution:{name:"Izmir Kâtip Çelebi University",country:{name:"Turkey"}}},{id:"339677",title:"Dr.",name:"Mrinmoy",middleName:null,surname:"Roy",slug:"mrinmoy-roy",fullName:"Mrinmoy Roy",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/339677/images/16768_n.jpg",biography:"An accomplished Sales & Marketing professional with 12 years of cross-functional experience in well-known organisations such as CIPLA, LUPIN, GLENMARK, ASTRAZENECA across different segment of Sales & Marketing, International Business, Institutional Business, Product Management, Strategic Marketing of HIV, Oncology, Derma, Respiratory, Anti-Diabetic, Nutraceutical & Stomatological Product Portfolio and Generic as well as Chronic Critical Care Portfolio. A First Class MBA in International Business & Strategic Marketing, B.Pharm, D.Pharm, Google Certified Digital Marketing Professional. Qualified PhD Candidate in Operations and Management with special focus on Artificial Intelligence and Machine Learning adoption, analysis and use in Healthcare, Hospital & Pharma Domain. Seasoned with diverse therapy area of Pharmaceutical Sales & Marketing ranging from generating revenue through generating prescriptions, launching new products, and making them big brands with continuous strategy execution at the Physician and Patients level. Moved from Sales to Marketing and Business Development for 3.5 years in South East Asian Market operating from Manila, Philippines. Came back to India and handled and developed Brands such as Gluconorm, Lupisulin, Supracal, Absolut Woman, Hemozink, Fabiflu (For COVID 19), and many more. In my previous assignment I used to develop and execute strategies on Sales & Marketing, Commercialization & Business Development for Institution and Corporate Hospital Business portfolio of Oncology Therapy Area for AstraZeneca Pharma India Ltd. Being a Research Scholar and Student of ‘Operations Research & Management: Artificial Intelligence’ I published several pioneer research papers and book chapters on the same in Internationally reputed journals and Books indexed in Scopus, Springer and Ei Compendex, Google Scholar etc. Currently, I am launching PGDM Pharmaceutical Management Program in IIHMR Bangalore and spearheading the course curriculum and structure of the same. I am interested in Collaboration for Healthcare Innovation, Pharma AI Innovation, Future trend in Marketing and Management with incubation on Healthcare, Healthcare IT startups, AI-ML Modelling and Healthcare Algorithm based training module development. I am also an affiliated member of the Institute of Management Consultant of India, looking forward to Healthcare, Healthcare IT and Innovation, Pharma and Hospital Management Consulting works.",institutionString:null,institution:{name:"Lovely Professional University",country:{name:"India"}}},{id:"310576",title:"Prof.",name:"Erick Giovani",middleName:null,surname:"Sperandio Nascimento",slug:"erick-giovani-sperandio-nascimento",fullName:"Erick Giovani Sperandio Nascimento",position:null,profilePictureURL:"https://intech-files.s3.amazonaws.com/0033Y00002pDKxDQAW/ProfilePicture%202022-06-20%2019%3A57%3A24.788",biography:"Prof. Erick Sperandio is the Lead Researcher and professor of Artificial Intelligence (AI) at SENAI CIMATEC, Bahia, Brazil, also working with Computational Modeling (CM) and HPC. He holds a PhD in Environmental Engineering in the area of Atmospheric Computational Modeling, a Master in Informatics in the field of Computational Intelligence and Graduated in Computer Science from UFES. He currently coordinates, leads and participates in R&D projects in the areas of AI, computational modeling and supercomputing applied to different areas such as Oil and Gas, Health, Advanced Manufacturing, Renewable Energies and Atmospheric Sciences, advising undergraduate, master's and doctoral students. He is the Lead Researcher at SENAI CIMATEC's Reference Center on Artificial Intelligence. In addition, he is a Certified Instructor and University Ambassador of the NVIDIA Deep Learning Institute (DLI) in the areas of Deep Learning, Computer Vision, Natural Language Processing and Recommender Systems, and Principal Investigator of the NVIDIA/CIMATEC AI Joint Lab, the first in Latin America within the NVIDIA AI Technology Center (NVAITC) worldwide program. He also works as a researcher at the Supercomputing Center for Industrial Innovation (CS2i) and at the SENAI Institute of Innovation for Automation (ISI Automação), both from SENAI CIMATEC. He is a member and vice-coordinator of the Basic Board of Scientific-Technological Advice and Evaluation, in the area of Innovation, of the Foundation for Research Support of the State of Bahia (FAPESB). He serves as Technology Transfer Coordinator and one of the Principal Investigators at the National Applied Research Center in Artificial Intelligence (CPA-IA) of SENAI CIMATEC, focusing on Industry, being one of the six CPA-IA in Brazil approved by MCTI / FAPESP / CGI.br. He also participates as one of the representatives of Brazil in the BRICS Innovation Collaboration Working Group on HPC, ICT and AI. He is the coordinator of the Work Group of the Axis 5 - Workforce and Training - of the Brazilian Strategy for Artificial Intelligence (EBIA), and member of the MCTI/EMBRAPII AI Innovation Network Training Committee. He is the coordinator, by SENAI CIMATEC, of the Artificial Intelligence Reference Network of the State of Bahia (REDE BAH.IA). He leads the working group of experts representing Brazil in the Global Partnership on Artificial Intelligence (GPAI), on the theme \"AI and the Pandemic Response\".",institutionString:"Manufacturing and Technology Integrated Campus – SENAI CIMATEC",institution:null},{id:"1063",title:"Prof.",name:"Constantin",middleName:null,surname:"Volosencu",slug:"constantin-volosencu",fullName:"Constantin Volosencu",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/1063/images/system/1063.png",biography:"Prof. Dr. Constantin Voloşencu graduated as an engineer from\nPolitehnica University of Timișoara, Romania, where he also\nobtained a doctorate degree. He is currently a full professor in\nthe Department of Automation and Applied Informatics at the\nsame university. Dr. Voloşencu is the author of ten books, seven\nbook chapters, and more than 160 papers published in journals\nand conference proceedings. He has also edited twelve books and\nhas twenty-seven patents to his name. He is a manager of research grants, editor in\nchief and member of international journal editorial boards, a former plenary speaker, a member of scientific committees, and chair at international conferences. His\nresearch is in the fields of control systems, control of electric drives, fuzzy control\nsystems, neural network applications, fault detection and diagnosis, sensor network\napplications, monitoring of distributed parameter systems, and power ultrasound\napplications. He has developed automation equipment for machine tools, spooling\nmachines, high-power ultrasound processes, and more.",institutionString:'"Politechnica" University Timişoara',institution:null},{id:"221364",title:"Dr.",name:"Eneko",middleName:null,surname:"Osaba",slug:"eneko-osaba",fullName:"Eneko Osaba",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/221364/images/system/221364.jpg",biography:"Dr. Eneko Osaba works at TECNALIA as a senior researcher. He obtained his Ph.D. in Artificial Intelligence in 2015. He has participated in more than twenty-five local and European research projects, and in the publication of more than 130 papers. He has performed several stays at universities in the United Kingdom, Italy, and Malta. Dr. Osaba has served as a program committee member in more than forty international conferences and participated in organizing activities in more than ten international conferences. He is a member of the editorial board of the International Journal of Artificial Intelligence, Data in Brief, and Journal of Advanced Transportation. He is also a guest editor for the Journal of Computational Science, Neurocomputing, Swarm, and Evolutionary Computation and IEEE ITS Magazine.",institutionString:"TECNALIA Research & Innovation",institution:{name:"Tecnalia",country:{name:"Spain"}}},{id:"275829",title:"Dr.",name:"Esther",middleName:null,surname:"Villar-Rodriguez",slug:"esther-villar-rodriguez",fullName:"Esther Villar-Rodriguez",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/275829/images/system/275829.jpg",biography:"Dr. Esther Villar obtained a Ph.D. in Information and Communication Technologies from the University of Alcalá, Spain, in 2015. She obtained a degree in Computer Science from the University of Deusto, Spain, in 2010, and an MSc in Computer Languages and Systems from the National University of Distance Education, Spain, in 2012. Her areas of interest and knowledge include natural language processing (NLP), detection of impersonation in social networks, semantic web, and machine learning. Dr. Esther Villar made several contributions at conferences and publishing in various journals in those fields. Currently, she is working within the OPTIMA (Optimization Modeling & Analytics) business of TECNALIA’s ICT Division as a data scientist in projects related to the prediction and optimization of management and industrial processes (resource planning, energy efficiency, etc).",institutionString:"TECNALIA Research & Innovation",institution:{name:"Tecnalia",country:{name:"Spain"}}},{id:"49813",title:"Dr.",name:"Javier",middleName:null,surname:"Del Ser",slug:"javier-del-ser",fullName:"Javier Del Ser",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/49813/images/system/49813.png",biography:"Prof. Dr. Javier Del Ser received his first PhD in Telecommunication Engineering (Cum Laude) from the University of Navarra, Spain, in 2006, and a second PhD in Computational Intelligence (Summa Cum Laude) from the University of Alcala, Spain, in 2013. He is currently a principal researcher in data analytics and optimisation at TECNALIA (Spain), a visiting fellow at the Basque Center for Applied Mathematics (BCAM) and a part-time lecturer at the University of the Basque Country (UPV/EHU). His research interests gravitate on the use of descriptive, prescriptive and predictive algorithms for data mining and optimization in a diverse range of application fields such as Energy, Transport, Telecommunications, Health and Industry, among others. In these fields he has published more than 240 articles, co-supervised 8 Ph.D. theses, edited 6 books, coauthored 7 patents and participated/led more than 40 research projects. He is a Senior Member of the IEEE, and a recipient of the Biscay Talent prize for his academic career.",institutionString:"Tecnalia Research & Innovation",institution:{name:"Tecnalia",country:{name:"Spain"}}},{id:"278948",title:"Dr.",name:"Carlos Pedro",middleName:null,surname:"Gonçalves",slug:"carlos-pedro-goncalves",fullName:"Carlos Pedro Gonçalves",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRcmyQAC/Profile_Picture_1564224512145",biography:'Carlos Pedro Gonçalves (PhD) is an Associate Professor at Lusophone University of Humanities and Technologies and a researcher on Complexity Sciences, Quantum Technologies, Artificial Intelligence, Strategic Studies, Studies in Intelligence and Security, FinTech and Financial Risk Modeling. He is also a progammer with programming experience in:\n\nA) Quantum Computing using Qiskit Python module and IBM Quantum Experience Platform, with software developed on the simulation of Quantum Artificial Neural Networks and Quantum Cybersecurity;\n\nB) Artificial Intelligence and Machine learning programming in Python;\n\nC) Artificial Intelligence, Multiagent Systems Modeling and System Dynamics Modeling in Netlogo, with models developed in the areas of Chaos Theory, Econophysics, Artificial Intelligence, Classical and Quantum Complex Systems Science, with the Econophysics models having been cited worldwide and incorporated in PhD programs by different Universities.\n\nReceived an Arctic Code Vault Contributor status by GitHub, due to having developed open source software preserved in the \\"Arctic Code Vault\\" for future generations (https://archiveprogram.github.com/arctic-vault/), with the Strategy Analyzer A.I. module for decision making support (based on his PhD thesis, used in his Classes on Decision Making and in Strategic Intelligence Consulting Activities) and QNeural Python Quantum Neural Network simulator also preserved in the \\"Arctic Code Vault\\", for access to these software modules see: https://github.com/cpgoncalves. 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Currently working as an Assistant Professor in the Department of Mathematics, Institute of Applied Science, Mangalayatan University, Aligarh. She taught so many courses of Mathematics of UG and PG level. Her research Area of Expertise is Functional Analysis & Sequence Spaces. She has been working on Ideal Convergence of double sequence. She has published 17 research papers in National and International Journals including Cogent Mathematics, Filomat, Journal of Intelligent and Fuzzy Systems, Advances in Difference Equations, Journal of Mathematical Analysis, Journal of Mathematical & Computer Science etc. She has also reviewed few research papers for the and international journals. 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Dr. Koprowski has authored more than a hundred research papers with dozens in impact factor (IF) journals and has authored or co-authored six books. Additionally, he is the author of several national and international patents in the field of biomedical devices and imaging. Since 2011, he has been a reviewer of grants and projects (including EU projects) in biomedical engineering.",institutionString:null,institution:{name:"University of Silesia",institutionURL:null,country:{name:"Poland"}}},subseries:[{id:"7",title:"Bioinformatics and Medical Informatics",keywords:"Biomedical Data, Drug Discovery, Clinical Diagnostics, Decoding Human Genome, AI in Personalized Medicine, Disease-prevention Strategies, Big Data Analysis in Medicine",scope:"Bioinformatics aims to help understand the functioning of the mechanisms of living organisms through the construction and use of quantitative tools. The applications of this research cover many related fields, such as biotechnology and medicine, where, for example, Bioinformatics contributes to faster drug design, DNA analysis in forensics, and DNA sequence analysis in the field of personalized medicine. Personalized medicine is a type of medical care in which treatment is customized individually for each patient. Personalized medicine enables more effective therapy, reduces the costs of therapy and clinical trials, and also minimizes the risk of side effects. Nevertheless, advances in personalized medicine would not have been possible without bioinformatics, which can analyze the human genome and other vast amounts of biomedical data, especially in genetics. The rapid growth of information technology enabled the development of new tools to decode human genomes, large-scale studies of genetic variations and medical informatics. The considerable development of technology, including the computing power of computers, is also conducive to the development of bioinformatics, including personalized medicine. In an era of rapidly growing data volumes and ever lower costs of generating, storing and computing data, personalized medicine holds great promises. Modern computational methods used as bioinformatics tools can integrate multi-scale, multi-modal and longitudinal patient data to create even more effective and safer therapy and disease prevention methods. Main aspects of the topic are: Applying bioinformatics in drug discovery and development; Bioinformatics in clinical diagnostics (genetic variants that act as markers for a condition or a disease); Blockchain and Artificial Intelligence/Machine Learning in personalized medicine; Customize disease-prevention strategies in personalized medicine; Big data analysis in personalized medicine; Translating stratification algorithms into clinical practice of personalized medicine.",annualVolume:11403,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/7.jpg",editor:{id:"351533",title:"Dr.",name:"Slawomir",middleName:null,surname:"Wilczynski",fullName:"Slawomir Wilczynski",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000035U1loQAC/Profile_Picture_1630074514792",institutionString:null,institution:{name:"Medical University of Silesia",institutionURL:null,country:{name:"Poland"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"5886",title:"Dr.",name:"Alexandros",middleName:"T.",surname:"Tzallas",fullName:"Alexandros Tzallas",profilePictureURL:"https://mts.intechopen.com/storage/users/5886/images/system/5886.png",institutionString:"University of Ioannina, Greece & Imperial College London",institution:{name:"University of Ioannina",institutionURL:null,country:{name:"Greece"}}},{id:"257388",title:"Distinguished Prof.",name:"Lulu",middleName:null,surname:"Wang",fullName:"Lulu Wang",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRX6kQAG/Profile_Picture_1630329584194",institutionString:"Shenzhen Technology University",institution:{name:"Shenzhen Technology University",institutionURL:null,country:{name:"China"}}},{id:"225387",title:"Prof.",name:"Reda R.",middleName:"R.",surname:"Gharieb",fullName:"Reda R. Gharieb",profilePictureURL:"https://mts.intechopen.com/storage/users/225387/images/system/225387.jpg",institutionString:"Assiut University",institution:{name:"Assiut University",institutionURL:null,country:{name:"Egypt"}}}]},{id:"8",title:"Bioinspired Technology and Biomechanics",keywords:"Bioinspired Systems, Biomechanics, Assistive Technology, Rehabilitation",scope:'Bioinspired technologies take advantage of understanding the actual biological system to provide solutions to problems in several areas. Recently, bioinspired systems have been successfully employing biomechanics to develop and improve assistive technology and rehabilitation devices. The research topic "Bioinspired Technology and Biomechanics" welcomes studies reporting recent advances in bioinspired technologies that contribute to individuals\' health, inclusion, and rehabilitation. Possible contributions can address (but are not limited to) the following research topics: Bioinspired design and control of exoskeletons, orthoses, and prostheses; Experimental evaluation of the effect of assistive devices (e.g., influence on gait, balance, and neuromuscular system); Bioinspired technologies for rehabilitation, including clinical studies reporting evaluations; Application of neuromuscular and biomechanical models to the development of bioinspired technology.',annualVolume:11404,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/8.jpg",editor:{id:"144937",title:"Prof.",name:"Adriano",middleName:"De Oliveira",surname:"Andrade",fullName:"Adriano Andrade",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRC8QQAW/Profile_Picture_1625219101815",institutionString:null,institution:{name:"Federal University of Uberlândia",institutionURL:null,country:{name:"Brazil"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"49517",title:"Prof.",name:"Hitoshi",middleName:null,surname:"Tsunashima",fullName:"Hitoshi Tsunashima",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYTP4QAO/Profile_Picture_1625819726528",institutionString:null,institution:{name:"Nihon University",institutionURL:null,country:{name:"Japan"}}},{id:"425354",title:"Dr.",name:"Marcus",middleName:"Fraga",surname:"Vieira",fullName:"Marcus Vieira",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00003BJSgIQAX/Profile_Picture_1627904687309",institutionString:null,institution:{name:"Universidade Federal de Goiás",institutionURL:null,country:{name:"Brazil"}}},{id:"196746",title:"Dr.",name:"Ramana",middleName:null,surname:"Vinjamuri",fullName:"Ramana Vinjamuri",profilePictureURL:"https://mts.intechopen.com/storage/users/196746/images/system/196746.jpeg",institutionString:"University of Maryland, Baltimore County",institution:{name:"University of Maryland, Baltimore County",institutionURL:null,country:{name:"United States of America"}}}]},{id:"9",title:"Biotechnology - Biosensors, Biomaterials and Tissue Engineering",keywords:"Biotechnology, Biosensors, Biomaterials, Tissue Engineering",scope:"The Biotechnology - Biosensors, Biomaterials and Tissue Engineering topic within the Biomedical Engineering Series aims to rapidly publish contributions on all aspects of biotechnology, biosensors, biomaterial and tissue engineering. We encourage the submission of manuscripts that provide novel and mechanistic insights that report significant advances in the fields. Topics can include but are not limited to: Biotechnology such as biotechnological products and process engineering; Biotechnologically relevant enzymes and proteins; Bioenergy and biofuels; Applied genetics and molecular biotechnology; Genomics, transcriptomics, proteomics; Applied microbial and cell physiology; Environmental biotechnology; Methods and protocols. Moreover, topics in biosensor technology, like sensors that incorporate enzymes, antibodies, nucleic acids, whole cells, tissues and organelles, and other biological or biologically inspired components will be considered, and topics exploring transducers, including those based on electrochemical and optical piezoelectric, thermal, magnetic, and micromechanical elements. Chapters exploring biomaterial approaches such as polymer synthesis and characterization, drug and gene vector design, biocompatibility, immunology and toxicology, and self-assembly at the nanoscale, are welcome. Finally, the tissue engineering subcategory will support topics such as the fundamentals of stem cells and progenitor cells and their proliferation, differentiation, bioreactors for three-dimensional culture and studies of phenotypic changes, stem and progenitor cells, both short and long term, ex vivo and in vivo implantation both in preclinical models and also in clinical trials.",annualVolume:11405,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/9.jpg",editor:{id:"126286",title:"Dr.",name:"Luis",middleName:"Jesús",surname:"Villarreal-Gómez",fullName:"Luis Villarreal-Gómez",profilePictureURL:"https://mts.intechopen.com/storage/users/126286/images/system/126286.jpg",institutionString:null,institution:{name:"Autonomous University of Baja California",institutionURL:null,country:{name:"Mexico"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"35539",title:"Dr.",name:"Cecilia",middleName:null,surname:"Cristea",fullName:"Cecilia Cristea",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYQ65QAG/Profile_Picture_1621007741527",institutionString:null,institution:{name:"Iuliu Hațieganu University of Medicine and Pharmacy",institutionURL:null,country:{name:"Romania"}}},{id:"40735",title:"Dr.",name:"Gil",middleName:"Alberto Batista",surname:"Gonçalves",fullName:"Gil Gonçalves",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYRLGQA4/Profile_Picture_1628492612759",institutionString:null,institution:{name:"University of Aveiro",institutionURL:null,country:{name:"Portugal"}}},{id:"211725",title:"Associate Prof.",name:"Johann F.",middleName:null,surname:"Osma",fullName:"Johann F. 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