Medicinal plants are one of the nature’s greatest gifts to the mankind. Each plant will have an exquisite deal of character, which can act as an antidote to various of diseases. Traditional medicine has become a vital alternative source of medicine all over the world today with some approximation of about 80% of the primary health care system in some developing countries. Medicinal plants are known to comprise of hundreds of active constituents that may be potentially useful for the development of therapeutic agents. The development of therapeutic agents involves the isolation and identification of bioactive compounds from plant materials which is crucial for drug discovery. Researchers from all around the globe have focused on drug discovery from the natures’ wonder medicinal plants, forming an important group of complementary and alternative medicine (CAM) therapy. West Godavari is a part of Andhra Pradesh, India, which hosts several plants that have high therapeutic significance. Each of the plants has a unique feature which can be employed for healing of various lethal diseases. The present examination intends to review the therapeutic plant assets of West Godavari area Andhra Pradesh. This evaluation also offers the critical elements which include medicinal properties of various medicinal plants found in West Godavari district of Andhra Pradesh, India.
- drug discovery
- traditional medicine
- West Godavari district
The great thing that nature has given us is the medicinal plants. Each plant will have a great deal of character, which can act as an antidote against different types of diseases.
Traditional medicine has become a vital alternative source of medicine all over the world today with some approximation of about 80% of the primary health care system in some developing countries (e.g., Nigeria, Ghana, China, and India [1, 2]).
India has a recognized traditional system of medicine, that is, Ayurveda, Siddha, Unani, Homeopathy, Yoga, and Naturopathy which placed India in a unique position in the world .
As the growth of knowledge has increased, the number of new plant-derived drugs grow at an accelerated pace. India has an enormous wealth of medicinal plants, and often it has been referred to as the Medicinal Garden of the world .
Medicinal plants are known to comprise hundreds of active constituents that may be potentially useful for the development of therapeutic agents. The development of therapeutic agents involves Identification and segregation of bioactive compounds from plant materials that are crucial for drug discovery .
Researchers from all around the globe have focused on drug discovery from the nature’s wonder medicinal plants, an important group of complementary and alternative medicine (CAM) therapy .
The man has acclimated himself with plants and utilized them in an assortment of courses all through the ages. Primitive man looking for nourishment and to adapt efficiently to human sufferings started to recognize those plants appropriate for restorative reason from others with complete pharmacological activity. This connection between plants and man has developed, and many plants came to be utilized as medicines. The development of information to cure infections proceeded at a quick pace and various new plant-derived drugs expanded in this manner.
Herbs employed in ancient medicines represent a tiny, low portion of present plants solely. With the advances in informative innovation and science, many bioactive concoction substances are distinguished in plants or foodstuffs through phytochemical and pharmacological studies.
The clinical utilization of plants portrayed in Indian Vedas for curing distinctive maladies. In the present setting, the conventional arrangement of pharmaceutical is broadly acknowledged and drilled by individuals around the world.
The natural solution is drilled around the world. For a considerable length of time, individuals have swung to natural solutions for basic cure illnesses, for example, colds, sensitivity, annoy stomachs, and toothaches, and the pattern is continually expanding. In this way, there has been a move in general pattern from manufactured to homegrown solutions.
The advancement of plant-derived drugs began when improvement of science. The homegrown drug is compelling, minor symptom, and moderate than the medications purchased from an allopathic pharmaceutical. Homegrown medications incorporate herbs, homegrown materials, natural arrangements, and homegrown items that contain diverse parts of plants or other plant materials as dynamic fixings.
As the worldwide utilization of homegrown therapeutic items keeps on developing and numerous, the newest items are brought into the market, general medical problems and concerns encompassing their well-being are likewise progressively perceived. Although some homegrown herbs have promising potential and are utilized, a considerable lot of them stay untested and their utilization likewise not observed.
It has turned out to be fundamental, subsequently, to outfit the overall population incorporating human services experts with adequate data to encourage better comprehension of the dangers related to the utilization of these items and to guarantee that all solutions are protected and of reasonable quality. Discussion in this review is restricted to lethality-related issues, and significant well-being concerns are emerging from the utilization of homegrown drugs and additional factors advancing them. Some essential difficulties related to the successful checking of security of these homegrown cures are additionally featured to refocusing appropriate administrative offices on the requirement for viability and guaranteeing sufficient assurance of general well-being and advancing well-being.
The worldwide acknowledgment and utilization of natural medicines and related items keep on assuming exponential increment. Issues identifying with unfavorable responses as of late are additionally ending up more distinctive, expanding in common and no longer accessible to refute as a result of prior misguided judgment with regards to or classifying homegrown restorative items as “protected” because they are getting from “characteristic” source. In this manner, regulatory approaches on homegrown pharmaceuticals should be institutionalized and reinforced on a worldwide scale. Pertinent administrative experts in various nations of the world should be proactive and keep on putting proper set up measures to secure the general well-being by guaranteeing that every single natural prescription endorsed available to be purchased sheltered and of reasonable quality. Suppliers of pharmaceuticals, for example, doctors, attendants, and drug specialists, regularly have little preparing in and comprehension of how homegrown solutions influence the well-being of their patients. Satisfactory preparation is present extremely basic since most patients are regularly on different sorts of the solution or non-professionally prescribed drugs. Additionally, it is vital that all suppliers of natural solutions are adequately enabled to assume a part in observing well-being of homegrown prescriptions. This, be that as it may, ought to be in a joint effort with the traditional healers. For this to be successful, it is basic to make a climate of trust to encourage satisfactory sharing of information about the utilization and well-being of homegrown solutions. Truth be told to suppliers of homegrown solutions, and patients/shoppers are imperative for the version of possibly genuine dangers from misuse of natural medications. The supplier must demonstrate adequate responsibility toward understanding the utilization of homegrown drugs.
West Godavari is a part of Andhra Pradesh, India, which hosts several plants that have high medicinal importance. Each of the plants has a unique feature which can heal lethal diseases. Some researchers have drawn some plants into attention from lots of surveys. It also hosts traditional healers who can efficiently cure some of the deadly diseases.
The traditional plant healing has brought a significant breakthrough in curing diseases very efficiently. The nutraceutical companies have isolated plant compounds based on the knowledge provided by the traditional healers. An adequate amount of knowledge is still to be known from the traditional healers. There is a substantial increase in the use of Ayurvedic medicines and medicines derived from plant sources. The reason being its efficacy and lack of side effects, and there is an economic point of view as well. Based on the information given by the traditional healing system, several modern scientific studies are being conducted on the various medicinal plants.
Some of the medicinal plants have been perished because of urbanization. The ancient knowledge about medicinal plants had not been documented, and many of the valuable plants are at the edge of extinction. The government and NGO should take necessary conservatory steps to avoid extinction of valuable medicinal plants.
Several bioactive compounds isolated from medicinal plants are in excess demand in nutraceutical companies.
The present study aims to review the medicinal plant resources of West Godavari district, Andhra Pradesh. This review also deals with the critical aspects such as medicinal properties of various medicinal plants present in West Godavari district of Andhra Pradesh, India. This article deals with the medicinal properties of plants which are implicated in various diseases such as jaundice, cardiac diseases, asthma, cancer, skin diseases, diarrhea, conjunctivitis, ulcers, diabetes, leprosy, syphilis, and neural diseases.
This article also deals with the scientific studies conducted by the researchers on numerous medicinal plants present in West Godavari.
2. Medicinal plants of West Godavari
It is being cultivated in Peru and Brazil and is grown mostly in the Bahamas and occasionally in southern Florida, Bermuda, the east coast of Malaysia, and throughout Southeast Asia and the Philippines [8, 9].
In Siddha System of Medicine, it has been using as a remedy for jaundice, piles, ulcers, and leprosy .
2.2.1. Scientific studies on
This plant is proved to have diuretic activity , antimycotic activity , anti-arthritic activity , anti-inflammatory and anti-asthmatic activity , hypoglycemic activity , anticonvulsant activity , wound healing activity , antidiarrhoeal activity , antimalarial , and hepatoprotective activity .
2.3.1. Scientific studies on
This plant is demonstrated to have antibacterial activity , diuretic activity , nephroprotective activity , neuroprotective activity , bronchodilator activity , effect on neuromuscular antioxidant activity , anticonvulsant activity , antispasmodic activity .
2.4.1. Scientific studies on
This plant is proved to have antidiabetic activity , antimutagenic activity , antimicrobial activity , antifungal activity , antidiarrhoeal activity , antiviral activity , nematicidal activity , antioxidant activity , and abortifacient activity .
2.6.1. Scientific evidences
This plant is verified to have antidiabetic activity , antibacterial activity , hepatoprotective activity , analgesic/anti-inflammatory activity , antitumor activity , anticonvulsant activity , antiproliferative and antiestrogenic activity , cytological activity , bronchial asthma , and anti-fibrinolytic activity .
2.7.1. Scientific evidences
This plant is verified to have hepatoprotective activity , antioxidant activity , antipyretic activity , anthelmintic activity , anti-inflammatory activity , antidiarrhoeal activity , spasmolytic activity , antidiabetic activity , antiulcer activity , and wound healing activity .
It is a medicinal plant native to the Western Ghats and is chiefly found in tidal forests of India.
2.10.1. Scientific evidences
This plant is proved to have antihyperglycemic and antilipidperoxidative effects , antihyperammonemic effect , anti-inflammatory activity , antiviral activity , antifilarial potential , ulceroprotective activity , nootropic activity , and antinociceptive activity .
2.11.1. Scientific evidences
This plant is shown to have anti-apoptosis and antioxidant , analgesic activity , immunomodulatory activity , anticancer and antitumor activity , antidiabetic activity , antifertility activity , anti-snake venom activity , melanin-inhibiting activity , and antiulcer activity .
2.12.1. Scientific evidences
This plant is shown to have antimicrobial and antifungal , antioxidant activity , anti-implantation activity , anti-inflammatory and free radical scavenging activity , central analgesic activity , anti-tumor activity , larvicidal and adult emergence inhibition activity , antiulcer activity , molluscicidal, insecticidal and larvicidal activity , antidiabetic activity , cytotoxic activity , and antihistaminic activity .
2.13.1. Scientific evidences
This plant is revealed to have antiallergic activity , gastroprotective activity , antioxidant activity , CNS activity , anti-inflammatory activity , antihyperlipidemic activity , antidiarrhoeal activity , antipyretic activity , antispasmodic activity , and antiviral activity .
In Ayurvedic practices,
2.14.1. Scientific evidences
This plant is shown for its antioxidant activity , anti-inflammatory activity , antiulcer activity , antidiabetic activity , nephroprotective activity , cytotoxicity , anti-hypercholestrolemic activity , hepatoprotectivity , cardiovascular activity , and anticancer activity .
2.16.1. Scientific evidences
This plant is demonstrated to have diuretic activity , aphrodisiac activity , antiurolithic activity , immunomodulatory activity , antidiabetic activity , hypolipidemic , central nervous system (CNS) activity , anticancer activity , and larvicidal activity .
2.17.1. Scientific evidences
This plant is demonstrated to have antibacterial activity , antiamoebic and immunomodulatory activities , antianaphylactic and adaptogenic activities , antiviral activity , antimutagenic and anticarcinogenic activities , anti-arthritic activity , antidiabetic and retinoprotective activities , and hepatoprotective activity .