Open access peer-reviewed chapter

Current Outcomes Following Reverse Total Shoulder Arthroplasty: A Composite

By Sydney C. Cryder, Samuel E. Perry and Elizabeth A. Beverly

Submitted: August 18th 2017Reviewed: November 17th 2017Published: December 20th 2017

DOI: 10.5772/intechopen.72545

Downloaded: 913


Reverse Total Shoulder Arthroplasty (RTSA) is a popular treatment for patients with rotator cuff damage, glenohumeral arthritis, complex fractures, and previously failed total shoulder arthroplasty given its ability to alleviate pain and increase range of motion and function. Although RTSA significantly improves functionality, pain, and satisfaction, patients need to be given realistic expectations for when to expect improvements, peak performance, and plateaus as well as potential risks for negative outcomes. As with any surgical procedure, patients are at risk for intraoperative, perioperative, short-term, and long-term complications. Thus, the purpose of this review is to discuss the short-term and long-term complications, metrics, and length of follow-up for patients who have undergone RTSA. In addition, we provide recommendations for a cut-off point between short-term and long-term outcomes for RTSA.


  • reverse total shoulder arthroplasty
  • joint prosthesis
  • shoulder joint surgery
  • rotator cuff surgery
  • short-term outcomes
  • long-term outcomes

1. Introduction

In 1985, Dr. Paul Grammont introduced a new system for reverse total shoulder prosthesis that revolutionized the field by focusing on four key features: (1) the prosthesis must be inherently stable; (2) the lever arm of the deltoid must be effective from the initiation of the movement; (3) the glenosphere must be large and the humeral cup small to create a semi-constrained articulation; (4) the center of rotation must be fixed, medialized and distalized with respect to the glenoid surface [1, 2]. To this day, Grammont’s core features are still the mainstay. Of course, modern prosthetics have been modified since 1985 to avoid scapular notching and impingement between the greater tuberosity and the coracoacromial arch and to maximize compressive forces while minimizing shear forces [2, 3].

These advancements contributed directly to the increased utilization of Reverse Total Shoulder Arthroplasty (RTSA) [4]. In fact, in the last ten years, the number of RTSAs nearly tripled in the United States [5]. Reverse Total Shoulder Arthroplasty (RTSA) is a popular treatment for patients with rotator cuff damage, glenohumeral arthritis, complex fractures, and previously failed total shoulder arthroplasty given its ability to alleviate pain and increase range of motion and function. Although RTSA significantly improves functionality, pain, and satisfaction, patients need to be given realistic expectations for when to expect improvements, peak performance, and plateaus as well as potential risks for negative outcomes. As with any surgical procedure, patients are at risk for intraoperative, perioperative, short-term, and long-term complications. Thus, the purpose of this review is to discuss the short-term and long-term complications, metrics, and length of follow-up for patients who have undergone RTSA. In addition, we provide recommendations for a cut-off point between short-term and long-term outcomes for RTSA.

Ease range of motion and function in patients with glenohumeral joint disease, displaced proximal humeral fractures, rotator cuff tear arthropathy, severe irreparable rotator cuff tears, rheumatoid arthritis, and failed shoulder arthroplasty [1, 2, 3, 6, 7, 8].


2. Surgical approach

The surgical technique for RTSA can be accomplished via two approaches: deltopectorally or superolaterally [3, 9]. The deltopectoral approach is the most common and requires an experienced surgeon [10]. This surgical technique begins with an incision overlying the deltopectoral interval, preserving the cephalic vein, then tenotomizing the biceps tendon and the subscapularis if still intact [3, 11, 12]. Next, the joint capsule is circumferentially released and humeral head exposed to perform a humeral head osteotomy. The humeral head is then reamed and broached. Subsequently, the glenoid is exposed, the labrum excised, and the glenoid prepared. The guidewire for the glenoid reamer is placed inferiorly so that the glenoid baseplate will be flush with the inferior border of the native glenoid rim. This will help decrease the risk of scapular notching. By adding an inferior tilt to the position of the baseplate, the risk of scapular notching can be decreased, which in turn, improves compressive forces and helps avoid shear forces on the glenoid component. The baseplate is impacted in place, and secured with screws to securely fix the baseplate to the patient’s native glenoid. The selected glenosphere is then secured to the baseplate with a Morse Taper fixation mechanism. The selection of the appropriately sized glenosphere is multifactorial. It is based on the patient’s size (i.e., 42 mm for larger patients, 39 mm for average size patients, 36 mm for smaller patients) and individual patient pathologies. Glenosphere components are available in central, lateral offset, and inferior offset designs.

Next, the humeral stem is prepared by sounding the inner diameter of the humeral shaft and broaching it to the appropriate size. The final implant is tested with the spacer trials in order to gain proper stability and range of motion. Then the real implants are seated and the shoulder is reduced. Lastly, the subscapularis is reattached and the biceps are tenodesed with heavy nonabsorbable sutures that are placed through drill holes in the humeral metaphysis prior to seating of the final implant. However, recent research acknowledges the controversy surrounding the reattachment of the subscapularis due to the potential for increasing the likelihood of dislocation [13]. The deltopectoral-interval is re-approximated and the incision closed. The patient is placed in a shoulder abduction sling for a period of immobilization lasting two to 6 weeks with a home physical therapy program [14]. As with all orthopedic procedures, the rehabilitation protocol is patient specific and additional rehabilitation may be deemed necessary if the patient needs to strengthen external rotation [14].


3. Outcome timeline

What constitutes a short-term versus a long-term outcome? One of the objectives of this review is to address the lack of clarity in the literature regarding the timeline of short-term and long-term outcomes [15]. Bacle and colleagues [15] identified that the majority of mechanical loosening reports occurred outside of the first 2 years following a reverse total shoulder arthroplasty. In contrast, dislocation, infection, and poor seating of the glenoid component were reported within the first 2 years postoperatively; a ratio of 3 to 1 for complications reported before and after the two-year mark [15]. Furthermore, Bacle and colleagues [15] defined medium-term follow-up as a mean of 39 months and long-term follow-up as a mean of 150 months. Similarly, Otto and colleagues [16] argued that a follow-up of period of 24 months was a relatively short time frame to adequately capture long-term complications. Thus, 2 years may be a respectable partition between short-term and long-term outcomes.


4. Outcome quantification

The language of RTSA outcomes is a complex task given the wide range of outcomes metrics. The most common scoring methods include the following: Range of Motion (ROM), Constant-Murley Score (CMS), American Surgeons of Elbow and Shoulder score (ASES), Visual Analogue Score (VAS), and the Simple Shoulder Test (SST). Other methods include but are not limited to the UCLA Shoulder Score and the Shoulder Pain and Disability Index (SPADI) [17, 18, 19]. The CMS, first published in 1987, is comprised of four sections: two of which are self-reported by the patient—pain and activities of daily living, the remaining two are reported by the physician—range of motion and strength [20]. Concerns were raised regarding the score’s ability to account for age and gender; thus, the modified version adjusts for both [17]. The ASES was created with the goal of developing a universal outcome measure; it too contains patient-reported and physician-reported parts. In addition, the ASES has demonstrated appropriate validity and reliability in assessing operative and non-operative interventions for shoulder pathology [17]. However, it’s appraisal of functionality may be somewhat limited among the older adult population; for example, the questions about “do usual sport” and “throw ball overhand” may not be relevant [19]. Patient-reported pain is an outcome that necessitates acknowledgement, which may be quantified by utilizing the VAS [21]. The VAS uses a line measuring 100 mm with pain extremes indicated on either end; no pain and worst pain [21]. The patient marks along the continuum where he/she believes their pain is best described; the score is then represented by a distance in millimeters [22]. Finally, the SST, is used to evaluate patient-reported functionality associated with various shoulder pathology, including rotator cuff arthropathy, osteoarthritis, rheumatoid arthritis, and adhesive capsulitis [17, 18]. This questionnaire consists of 12 questions that ask the patient whether he/she may perform the given activity [18].


5. Short-term outcomes

Table 1 reviews the outcome measures and length of follow-up from numerous surgical studies. Based on these findings, short-term outcomes for RTSA occur postoperatively within the first 24 months. It also addresses the variation in components and metrics used in each study.

StudySample sizeAgeFollow upComplicationsComponent variabilityRisk factorsScoring Mechanism
Alentorn-Geli et al (2017)3877–83 years3–60 monthsInfection
Glenoid loosening
Component Dislocation
Comprehensive reverse shoulder system (Biomet)
Encore reverse (DJO Global)
Delta reverse shoulder System
Tobacco use
Increased age
Anakwenze et al (2016)114745–84 years3–36 monthsAseptic revision
Surgical site infection
-Increased BMI
Increased age
Bacle et al (2017)18623–86 years (72.7 mean)24–150 monthsDislocation
Scapular Notching
Nerve Palsy
Glenoid Loosening
Humeral Loosening
Glenoid fracture Revisions
164 Delta III (DePuy)
27 Aequalis (Tournier)
Increased ageCMS
Ek et al. (2013)4146–64 years60–171 monthsInfection
Nerve Palsy
Component Wear
Glenoid loosening
Glenoid component 36mm, 40mm, or 42 mm
Delta III (DePuy) (lateralized humeral polyethylene cup)
Anatomical Shoulder System
(Zimmer) (6mm medialized humeral cup)
Previous surgery on same shoulderCMS
Validated electronic dynamometer
Feeley et al (2014)5453–81 years30 monthsScapular notchingZimmer Reverse Trabecular
Metal System
36mm glenosphere 3mm lateralized
ASES score
Friedman et al (2017)59150–93 years24 month minimum (37 month mean)Component instability
Scapular notching
Equinoxe rTSA (Exactech)-SST
ASES score
UCLA score
Jonusas et al (2017)2755–85 years45 monthsHeterotopic ossification
Tubercule malposition
Arrow shoulder system with less medialized CoR-SST
Mollon et al (2016)47653–90 years22–93 monthsScapular notching
Component Loosening
Humeral fracture
Scapular fracture
Equinoxe rTSA (Exactech) 36 mm, 40mm, or 42mm glenosphere lateralized 2.3mmIncreased age
Increased BMI
ASES score
Muller et al (2017)6868–79 years6–60 monthsGlenoid migration
Component loosening
SMR reverse shoulder system
(Lima Switzerland SA)
36mm or 40mm glenosphere
Increased ageCMS SPADI
Otto et al. (2017)6721–54 years24–144 monthsScapular notching
Humeral lucency
Glenoid screw lucency
Fracture (humeral, scapular)
Humeral dissociation
Reverse shoulder system (DJO Surgical)Prior shoulder surgerySST
ASES score
Randelli et al (2015)22664–72 years3.8 yearsRevision
Delta III-Constant Score
ASES score
Simovitch et al (2015)91260–78 years2 weeks–139 months-Equinoxe rTSA system (Exactech)-SPADI
ASES score
UCLA score
Constant score
Statz et al (2016)4153–83 years2–7.3 yearsScapular notching
Nerve palsy
Heterotopic ossification
Encore reverse shoulder
Prosthesis (DJO Surgical)
Delta III, Delta Xtend (DePuy)
Comprehensive prosthesis (Biomet)
Aequalis Reversed Shoulder (Tournier)
Increased BMI
Previous shoulder surgery
Tobacco use
Diabetes mellitus
ASES score
Wierks et al (2007)2045–88 years3–21 monthsFracture
Poor screw fixation
Nerve palsy
Infection/ Abscess
Heterotopic ossification
Scapular notching
DePuy reverse shoulder prosthesis
Tournier reverse shoulder prosthesis
Williams et al (2017)1745–91 years10–67.7 monthsDislocation
Component migration
Biomet reverse adapter (Bio-Modular to Comprehensive conversion)-VAS
ASES score
Yoon et al (2017)3566–84 years12–35 monthsScapular notching
A/C joint separation
Acromial fracture
Aequalis reverse arthroplasty system (Tournier)Increase BMI
Diabetes mellitus
ASES score
Constant score

Table 1.

Comparison of outcome measures and length of follow-up for patients undergoing reverse total shoulder arthroplasty.

ASES = American shoulder and elbow surgeons; SPADI = shoulder pain and disability index; ROM = range of motion; UCLA = University of California Los Angeles score; SST = simple shoulder test; VAS = visual analogue score; FF = forward flexion; ER = external rotation; BMD = bone mineral density.

RTSA significantly improves functionality, pain, and satisfaction; but when are patients expected to experience peak performance with a new prosthesis? Is there a point in time when a patient should expect a plateau in their improvements over time? In 2015, Simovitch and colleagues [23] demonstrated that at the 6-month follow-up, less than 5% of patients reported decreases in SST, UCLA Shoulder Score, CMS, ASES, SPADI. More importantly, “full improvement” was achieved in the 12–24 month range [23]. Thus, they concluded that the majority of improvement occurred within the first 6 months, as evidenced by the scores for each of the five measures [23]. These findings stress the importance of patient selection, expectations for RTSA, expertise in intraoperative optimization, and strict postoperative physical therapy management. The concept of rapid improvement during the first 6 months with plateau at 12 months was also reported by Muller and colleagues in 2017 [24], in which flexion, abduction, and external rotation in 90 degrees of abduction demonstrated profound increases by 42°, 38° and 33° respectively at 6 months. Additional follow-ups at 12, 24, and 60 months displayed minimal additional improvement [24]. Supplementary evidence of RTSA success was seen by Yoon and colleagues [25] in 2017 with forward flexion increase of 64°, external rotation increase of 13° and pain reduction of (−3) at 12 months postoperatively.

Two factors that have been shown to increase CMS and ROM testing during the short-term period are deltoid volume [25] and glenosphere size [24] respectively. Preoperative deltoid muscle volume was an independent prognostic factor for functional outcomes with CMS (p = 0.011), underscoring the importance of patient selection and discussing the potential for negative outcomes such as atrophied deltoid muscle [25]. Likewise, Muller and colleagues [24] conducted a retrospective analysis in 2017, to demonstrate that patients that had received a 44 mm glenosphere had greater external rotation in adduction and abduction strength over the 36 mm glenosphere. Moreover, they found no significant differences in functional scores or complication rates [24].

Complications are a critical component of RTSA. Patients need to be counseled on intraoperative, perioperative, and notably, short-term complications. The most common intraoperative complications are glenoid or humeral fractures along with poor screw fixation [12]. The consequence of poor screw fixation is its lasting impact and conversion to long-term complications such as glenoid screw lucency. Zhou and colleagues [13] discussed the prevention techniques, such as hand reaming the humerus and preserving glenoid bone stock by avoiding reaming beyond subchondral bone margin. Postoperative short-term complications dominate the outcomes of RTSA and range from scapular notching, infection, dislocation, revision, nerve palsy, or even heterotopic ossification.

Scapular notching is by far the most common complication during the first 24 months postoperative. Scapular notching has an incidence of 38%, 57%, 55% and 73% in four recent studies respectively [12, 15, 24, 25]. These findings oblige additional research to review instrumentation and confirm incidence levels on scapular notching in RTSA. In 2014, Feeley and colleagues [12] found that decreasing the neck-shaft angle or a higher inclination angle and 3 mm lateral offset of the glenosphere prosthesis decreased the rate of scapular notching by 16%. Furthermore, Zhou and colleagues [13] assert that continued complication management, by adding inferior placement of the glenosphere, is “the most important factor in the avoidance of inferior impingement.” The next step is to investigate whether scapular notching will evolve, both de novo and from early to late stage scapular notching during short-term follow-up. An important question to consider is will the patient be free from scapular notching for the remainder of the prosthesis? [12] Feeley and colleagues [12] observed that of all the patients who did not experience scapular notching during the first 12 months (84% of patients), showed no new evidence of scapular notching during follow-ups up to 30 months. Conversely, Bacle and colleagues [15] found that after early scapular notching diagnoses were made, there was a 39% increase in the rate of notching beyond the 2-year follow-up period. Thus, superfluous research is essential to answer this question.

Another common short term complication deals with postoperative stability resulting in shoulder dislocations. Wierks [12] and colleagues as well as Bacle [15] and colleagues found 10% and 22% of dislocations occurred during the short term period. Of note, Bacle and colleagues [15] published that of the 15 dislocations documented in the sample size of 67, no cases were reported after the 2 year follow-up period. Zhou and colleagues [26] reviewed the most common and serious complications associated with RTSA and concluded that instability was a result of “lack of soft tissue tension, mechanical impingement, mismatch of the glenosphere and humeral socket size and improper version of the prosthesis”. Therefore, to obtain the best outcome for patients, extensive knowledge of the prosthesis is imperative, along with understanding how to achieve soft tissue tension using vertical offset of your acromion—greater tuberosity distance and lateral offset of the tuberosity-glenoid distance [26]. Conversely, controversy exists within the RTSA literature regarding the decision to repair the subscapularis. Friedman and colleagues showed that subscapularis repair proclaimed no statistical significance over no repair [27]. In the study, 340 patients with RTSA plus repair had 0% dislocation rate, versus 251 patients with RTSA without repair showing a 1.2% dislocation rate; stating the claim that RTSA plus subscapularis repair is not indicated due to the absence of increase in overall complication rates [27].

Lastly, infections can have serious ramifications on patient satisfaction as well as the overall outcomes of the RTSA, resulting in one or two-stage revisions. A study conducted by Wierks and colleagues [12] in 2009, had a 5% infection rate and a study by Bacle and colleagues [15] in 2017, had an infection rate of 12%. It is important to emphasize that Bacle and colleagues [15] documented 8 infections within the first 24 months as compared to only 2 cases in the 12 year follow-up period. In the same study, with regards to revision cases in the short-term period, 6 out of the 8 revision surgeries were caused by infections [15]. Thus, postoperative infections that occur in the first two years are the most common reason for revision surgery. In the review conducted by Zhou and colleagues [26] in 2015, they compared primary cases and revision cases, to find that revision cases were statistically higher than primary cases with regards to infections rates, 5.9% vs. 2.9% respectively. Propionibacterium acnesand Staphylococcus epidermidiswere the most commonly cultured organisms. Recommendations to decrease infections include continuation of preoperative antibiotics within one hour of incision and use of antibiotic-impregnated cement for surgeries that employ cement the humeral component [26].


6. Long-term outcomes

The patient’s age at the time of the arthroplasty plays a critical role in the survival of the prosthesis; younger patients (i.e., < 55 years of age) are more likely to be active in the workforce, while older patients are less likely to participate in physically strenuous activities and be retired [16]. In younger patients, prosthesis survival can exceed 10 years. For example, Bacle and colleagues [15] observed a 93% implant survival rate at 10 years; whereas Ek and colleagues [28] observed an implant survival rate of 88% at 5 years and 76% at 10 years postoperatively, regardless of any complications that may have arisen.

The RTSA has been shown to improve pain, strength, range of motion in abduction, external rotation, and forward flexion; in addition to showing improvement in metrics, such as ASES, SST, CMS, SPADI, and UCLA Should and UCLA Shoulder Score [16, 23, 24, 29]. Outcomes beyond the 24-month mark may be impacted by multiple variables, some of which include, prosthesis sizes, involvement of fracture, primary versus revision RTSA, and the lifestyle or activity level of the patient. In regards to repair of proximal humeral fractures, RTSA was found to provide superior results to a hemiarthroplasty for at least 5 years, respectively [30]. Muller and colleagues [24] investigated the size of the glenosphere, 36 mm and 44 mm, on functional outcomes following RTSA and found that both groups exhibited the most substantial progress in the first 6–24 months, followed by a plateau. Patients’ progress was monitored by measuring flexion, abduction, external rotation at 0° and 90° of abduction, internal rotation at 90° of abduction, CMS, SPADI, and strength (kg) in abduction. Interestingly, Anakwenze and colleagues [31] found that a higher body mass index (BMI) put a patient at risk for deep surgical site infection (SSI) up to 3 years following RTSA. Their study looked at the effects of increased BMI on postoperative outcomes following a RTSA and total shoulder arthroplasty (TSA). Every 5 kg/m [2] increase in BMI was associated with higher risk of 3-year deep SSI [31]. In addition to BMI, tobacco use influences the success of the prosthesis up to 12 years after an RTSA [32]. Hatta and colleagues [32] found that current smokers had an increased risk for infection, component loosening, and fractures compared to non-smokers. Specifically, they found that the percentage of patients with periprosthetic fractures jumped 20% at the 9 year mark after RTSA [32].

Although, as previously stated, this study implies 24 months as the short-term interval for outcomes following an RTSA, short-term complications have the potential to extend into the long-term if not addressed or managed appropriately—eventually affecting the longevity of the prosthesis. More commonly, long-term complications include glenoid and/or humeral component loosening, polyethylene component wear, and scapular notching. Less common long-term complications include deep SSI, dislocation, readmission, and fracture; which primarily occur within the first 2 years postoperatively. As mentioned above, glenoid or humeral loosening is the most common complication observed 2 years after RTSA, particularly with an increased risk following a previously failed shoulder arthroplasty and excess mechanical load related to increased BMI [15, 33]. Further, the incidence of component loosening doubles between the second and fifth year follow-up as reported by Alentorn-Geli and colleagues [29]. Particlization of the polyethylene component may be of concern with RTSA in younger patients due to necessary durability and lifespan of the implant. Riley and colleagues [34] investigated the outcomes following RTSA using a metal-on-metal design and concluded that it is not an acceptable alternative to RTSA in young patients; they maintain that the polyethylene component is the more suitable option. Ek and colleagues [28] conducted a study evaluating RTSA in patients younger than 65 years of age using two groups: revision RTSA and primary RTSA. This study observed an increased incidence of scapular notching at less than 12 months follow-up and greater than 10 years follow-up; with 56% of patients experiencing some degree of scapular notching overall [28]. Conversely, Mollon and colleagues [34] reported that only 10% of patients experienced scapular notching; noting that risk factors for scapular notching included lower body weight, lower BMI, and RTSA on the non-dominant upper extremity. It is also worth mentioning the correlation between longer-term follow-up and increasing incidence of scapular notching [34]; which may be attributed to variation in size and placement of the glenosphere, and center of rotation of the prosthesis.


7. Conclusion

Throughout this literature review, several limitations were encountered that include the following: unspecified “normal” postoperative physical rehabilitation protocols, risk factors pertinent to specific complications, and lack of research investigating the long term outcomes for RTSA. Additional research is needed to examine the aforementioned limitations to enhance future outcomes following RTSA.

Scapular notching, dislocations, and infections lead the forefront of persistent complications for RTSA. As evidenced in this literature review, the vast majority of improvement plateaus around 6 to 24 months. Thus, patient optimization may be accomplished by implementing a short-term course of preoperative physical therapy focused on shoulder girdle strength. Further, numerous inconsistencies and contradictions were observed in the literature regarding the impact of BMI on RTSA outcomes. Research requires further confirmatory evidence before making any strong conclusions about limiting the use of RTSA in patients with increased BMI. On the other hand, tobacco use negatively impacts the outcomes following RTSA by nearly doubling the overall complication rate.

© 2017 The Author(s). Licensee IntechOpen. This chapter is distributed under the terms of the Creative Commons Attribution 3.0 License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Sydney C. Cryder, Samuel E. Perry and Elizabeth A. Beverly (December 20th 2017). Current Outcomes Following Reverse Total Shoulder Arthroplasty: A Composite, Advances in Shoulder Surgery, Satish B. Sonar, IntechOpen, DOI: 10.5772/intechopen.72545. Available from:

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