List of top 10 yam producers in the World [5, 8]. Retrieved 24/05/2022.
\r\n\tThis book intends to provide the reader with a comprehensive overview of the current state-of-the-art novel imaging techniques by focusing on the most important evidence-based developments in this area.
",isbn:null,printIsbn:null,pdfIsbn:null,doi:null,price:0,priceEur:0,priceUsd:0,slug:null,numberOfPages:0,isOpenForSubmission:!0,isSalesforceBook:!1,isNomenclature:!1,hash:"d9159ce31733bf78cc2a79b18c225994",bookSignature:"Dr. Gabriel Cismaru",publishedDate:null,coverURL:"https://cdn.intechopen.com/books/images_new/11867.jpg",keywords:"Hypertrophic Cardiomyopathy, Dilated Cardiomyopathy, Restrictive Cardiomyopathy, Transesophageal Echocardiography, Intracardiac Echocardiography, 3-Dimensional Echocardiography, Adult Congenital Heart Disease, Tetralogy of Fallot, Transposition of the Great Vessels, Coronary Artery Disease, Risk Stratification, Revascularization",numberOfDownloads:null,numberOfWosCitations:0,numberOfCrossrefCitations:null,numberOfDimensionsCitations:null,numberOfTotalCitations:null,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"April 21st 2022",dateEndSecondStepPublish:"May 19th 2022",dateEndThirdStepPublish:"July 18th 2022",dateEndFourthStepPublish:"October 6th 2022",dateEndFifthStepPublish:"December 5th 2022",dateConfirmationOfParticipation:null,remainingDaysToSecondStep:"3 months",secondStepPassed:!0,areRegistrationsClosed:!0,currentStepOfPublishingProcess:4,editedByType:null,kuFlag:!1,biosketch:"Dr. Cismaru Gabriel is an Assistant Professor at the University of Medicine and Pharmacy Cluj-Napoca, certified in Cardiology. 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He has authored or co-authored peer-reviewed articles and book chapters in the field of cardiac pacing, defibrillation, electrophysiological study, and catheter ablation.",coeditorOneBiosketch:"Raluca Tomoaia is an MD, Ph.D. in novel techniques in Echocardiography at the University of Medicine and Pharmacy in Cluj-Napoca, Romania., assistant professor, and a researcher in echocardiography and cardiovascular imaging.",coeditorTwoBiosketch:null,coeditorThreeBiosketch:null,coeditorFourBiosketch:null,coeditorFiveBiosketch:null,editors:[{id:"191888",title:"Dr.",name:"Gabriel",middleName:null,surname:"Cismaru",slug:"gabriel-cismaru",fullName:"Gabriel Cismaru",profilePictureURL:"https://mts.intechopen.com/storage/users/191888/images/system/191888.png",biography:"Dr. Cismaru Gabriel is an assistant professor at the Cluj-Napoca University of Medicine and Pharmacy, Romania, where he has been qualified in cardiology since 2011. He obtained his Ph.D. in medicine with a research thesis on electrophysiology and pro-arrhythmic drugs in 2016. Dr. Cismaru began his electrophysiology fellowship at the Institut Lorrain du Coeur et des Vaisseaux Louis Mathieu, France, after finishing his cardiology certification with stages in Clermont-Ferrand and Dinan, France. He began working at the Rehabilitation Hospital\\'s Electrophysiology Laboratory in Cluj-Napoca in 2011. He is an experienced operator who can implant pacemakers, CRTs, and ICDs, as well as perform catheter ablation of supraventricular and ventricular arrhythmias such as ventricular tachycardia and ventricular fibrillation. He has been qualified in pediatric cardiology since 2022, and he regularly performs device implantation and catheter ablation in children. 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Reviewing the methodology and case study, this chapter explores the effectiveness, characteristics, and future prospects of the methodology. The discussion section also examines the capability of the methodology for the two significant changes, namely climate change and aging population, which have been presented in Chapter 1. Furthermore, the same section discusses how this methodology deals with the remaining issues in the existing Japanese systems, which have been raised in Chapter 2. After that, the final section summarizes the conclusions of the studies.
This section discusses the results of this study from the following five perspectives: (1) effects of the methodology for promoting sustainable home design, (2) characteristics of the methodology, (3) coordination with the existing systems, (4) applicability of the methodology, and (5) future research.
As illustrated in the case study, we have designed a detached house, following the methodology for promoting sustainable home design. That is to say, we have designed the house’s parts or elements, so that the elements’ variables satisfy their desired values as much as possible. After the house began to be used, we have obtained objective evaluations of the home’s environmental and sustainability performance as well as various comments on the home from the occupants and visitors.
First, all of the objective and quantitative evaluations have shown that the home has considerably high environmental performance. According to CASBEE for detached houses, a comprehensive assessment system, the home has readily been ranked in the highest “S,” with an extremely high score of built environment efficiency (BEE). Subsequently, the house has been classified into the highest “five star” by life cycle carbon minus (LCCM) certification, due to its higher energy saving performance and larger solar energy generation capacity. Meanwhile, the energy usage comparison with the average home has shown that the total energy usage of this home is equal to about 27% of the average home under the same conditions. The water usage comparison with the average home has also proved the higher water saving performance of this home. In addition, such high environmental performance has been highly evaluated when this house received the prize at the Sustainable Housing Awards.
The reactions of the occupants and visitors suggest that following the methodology has produced various favorable effects. On the other hand, any unfavorable side effects of utilizing the methodology have not been observed thus far. “Higher thermal insulation performance” has contributed to improve the occupant’s allergy symptoms, as well as improving comfort and reducing demand for heating and air-conditioning. “Placing areas relating to water use and hot water supply” has brought about reduction in time until hot water comes out, in addition to the reduction in materials for piping and energy for hot water supply. “Taking accessible and universal design into spatial elements, such as doorways and main access route to the entrance,” has already brought about present safety and comfort, above and beyond preparing the occupants for the future. “Protection of glass against impacts with shutters” has also contributed to prevent crimes and increase thermal performance, in addition to reduce the risk of being damaged by impacts such as fire and serious extreme weather events.
In this way, we have evaluated the home, which has been designed closely based on the methodology, from both the quantitative analyses and reactions of occupants and visitors. First, all of the quantitative analyses have shown that the home has significantly high environmental performance. The reactions of the occupants and visitors have also suggested that this home is comprehensively sustainable and comfortable. These assessment results indicate that if system users closely follow the methodology, they can comprehensively realize sustainable homes, which have high environmental performance.
The characteristics of the methodology includes (1) visualization of the whole picture for promoting sustainable home design, (2) user-friendliness, (3) comprehensiveness, (4) adaptability to regional differences, and (5) flexibility toward changes over time.
In addition,
Figure 5 in Chapter 4 has demonstrated the control system for promoting sustainable home design. This figure basically contains “sustainability,” “environmental, social, and economic problems,” and “disturbances” as system components. Moreover, “adaptation” to disturbances has been incorporated as a route to sustainability, as well as “solution” or “prevention” of the problems. Utilizing this basic scheme, this figure inclusively shows processes for promoting sustainable design on both new and existing homes with the “sustainable design guidelines” and “sustainability checklist.”
We consider that Figure 5 in Chapter 4 concisely explains the whole picture of the sustainable design processes with the guidelines and checklist. Accordingly, we expect that this visualization itself helps people concerned to easily understand that whole picture.
The “material and spatial elements” in the sustainable design guidelines and sustainability checklist are equal to “actual parts of houses.” Thus, the system users can smoothly design, check, evaluate, and inspect the house, by easily comparing the drawings or actual house with the guidelines or checklist [2]. In fact, the design process in the case study has supported the user-friendliness of the guidelines and checklist; the designers of the homebuilder readily accepted them and efficiently made the house’s drawings [2]. In addition, “correspondence between the elements and actual parts of houses” is unique to this methodology. On the other hand, the major existing Japanese methods, namely the housing performance indication system (HPIS), long-life quality housing (LQH) certification, and CASBEE for detached houses, do not possess this characteristic, as shown in Chapter 2.
Meanwhile, user-friendliness basically requires such methods to be “not complex” and “not long.” As cited before,
Originally, the “sustainable design guidelines” has been aimed comprehensively at showing the relationships between the standard home and sustainability. Therefore, we expected that following this methodology would lead to achieve comprehensive sustainable homes. The evaluation results of the home in the case study have been obtained as we expected. The CASBEE assessment results, namely the very high BEE score and high scores in all the six categories (Figure 14 in Chapter 5), have supported the comprehensiveness of the methodology as well as the comprehensive sustainability of that home.
This methodology, more specific the “element - variable - desired value” structure in the “sustainable design guidelines” and “sustainability checklist,” originally has a mechanism of easily adapting to regional differences. As shown in Figure 3 in Chapter 3, examining the relationships between important elements and stability conditions, system designers determine the elements’ variables and their desired values. This determination process has a mechanism of reflecting a variety of regional characteristics, including natural, geographical, social, and cultural features [2].
For instance, “resistance to earthquakes,” a variable of the framework, reflects a geological feature of Japan, namely “earthquake-prone.” This mechanism also enables the system designers to readily vary the guidelines, according to the region’s characteristics [2]. For example, if the region is in a strong wind area or snowy area, they can easily adjust the guidelines to the region, by adding “resistance to wind” or “resistance to snow load” as a variable of the framework [2].
Another example of reflecting regional features is “heat insulation” of the bathtub. We have attached importance to this variable, due to a Japanese cultural feature. Reducing heat loss from bath is important in Japan since people frequently take a bath and usually share the same hot water in the bathtub with their family members. On the other hand, in societies without such a lifestyle, it is easy for system designers to simply omit this variable.
The “element – variable – desired value” structure in the guidelines and checklist also leads to flexibility toward changes over time. Figure 1 explains this characteristic, mainly focusing on two major global changes progressing in the twenty-first century, namely “climate change” and “aging population.”
Flexibility of the methodology toward changes over time.
First, the course from “climate change” toward the materials or spatial elements passes through “mitigation measures/adaptation measures.” This course shows that system designers can take necessary mitigation/adaptation measures against climate change, by adjusting relevant elements, variables, and desired values. For example, when taking a measure of “improving thermal insulation performance,” we have added a variable “thermal insulation performance” to two material elements, namely “thermal insulation” and “windows and doors.” Similarly, we have easily taken an adaptation measure, by adding “protection of glass against impact” and “with shutters” as a variable and its desired value of the material element, “windows and doors.”
In addition, the broken dividing line between “mitigation measures” and “adaptation measures” in the block means that the two types of measures overlap each other. Such overlapping measures include “improving thermal insulation performance,” “harnessing natural energy,” “utilizing rainwater,” and “improving natural ventilation.” For instance, “improving thermal insulation performance” contributes to not only saving energy through reducing demand for heating and air-conditioning but also increasing resilience in extreme weather and crises.
On the other hand, Figure 1 shows two courses from “aging population” toward the material or spatial elements, that is, the routes through “mitigation measures/adaptation measures” and “accessible and universal design.” The broken line that connects “aging population” and “mitigation measures/adaptation measures” means that some of mitigation/adaptation measures benefit elderly people’s health. For example, “improving thermal insulation performance” can reduce the number of elderly people’s deaths and illnesses resulting from indoor coldness in cold weather. Likewise, “improving thermal insulation performance” and “improving natural ventilation” are expected to decrease heat stroke patients and deaths of the elderly in hot weather.
Meanwhile, the course through “accessible and universal design” represents that system designers can adopt accessible and universal design, by adjusting relevant elements, variables, and desired values. To be concrete, when compiling the guidelines, we first identified spatial elements related to such design, including “specified bedroom,” “doorways,” “stairs,” and “slope.” Subsequently, we have added necessary variables to these elements and set their desired values, so as to adopt accessible and universal design.
Furthermore, Figure 1 contains another change over time, that is, “technological changes.” Technological changes, including innovation in technology, are directly related with material elements; therefore, system designers can efficiently take such changes to relevant material elements. For instance, in the latest revision, we have easily taken “LED” as the desired value of “type of light” of “lighting fixtures.”
From the beginning, we have intended that this methodology is not used independently but coordinated with the existing Japanese systems that have been shown in Chapter 2. Such coordination is expected to exert favorable influences on the utilization of not only this methodology but also the existing methods.
First, when compiling the “guidelines” and “checklist,” we have aimed to provide reliability and incentives to utilize them. The guidelines and checklist use standard grades in the Japan housing performance indication standards (JHPIS) and assessment levels in CASBEE for detached houses, as the desired values of many variables. The JHPIS and CASBEE for detached houses, both of which are national systems, include technical information related to sustainable housing in the descriptions of the standard grades or assessment levels. Accordingly, when referring to the relevant descriptions in the JHPIS and CASBEE for detached houses, system users can obtain reliable related information or technical knowledge about the matters. Meanwhile, following the guidelines enables system users to receive a long-life quality housing (LQH) certification and higher ratings in CASBEE for detached houses. Obtaining a LQH certification leads to preferential treatment from the government, including tax credits; therefore, it can be an incentive for people to use the functions. Moreover, LQH-certified houses and CASBEE higher rated houses have a possibility of competitive superiority in the real estate market. Certified green or sustainable buildings have not yet gained obvious advantages in asset values in the Japanese real estate market, as shown in Chapter 2. However, such competitive superiority is expected to be established sooner or later also in Japan; therefore, it must be another incentive to use the functions.
On the other hand, the utilization of the user-friendly guidelines and checklist has a possibility of promoting the use of the existing public methods. Since the guidelines and checklist refer to CASBEE for detached houses, using these functions naturally leads to the utilization of this trustworthy system but relatively unknown system. Furthermore, when using the “checklist” for inspection or evaluation of existing homes, as a matter of course, “people involved” refer to the “JHPIS (for existing homes)” and “CASBEE for detached houses (existing building),” both of which have hardly been used thus far. The above coordination is expected to produce a synergy effect toward promoting sustainable housing design.
As demonstrated in Section 2.2.4., this methodology, more specific the “sustainable design guidelines” and “sustainability checklist,” has a feature of being adaptable to regional differences. Accordingly, it will be not difficult for system designers in another region to adapt these practical functions for that region [2]. That is to say, the system designers can make its regional version, through the examination of the elements and the adaptation of the elements’ variables and their desired values to the region’s characteristics [2].
As a matter of course, this methodology can be applied to other countries, as well as other regions. When system designers make the guidelines and checklist in other countries besides Japan, they specify variables and their desired values, referring to systems related to buildings and housing used in that country. In such cases, there are two main approaches: (1) specification based on the standards required by building codes and (2) use of criteria shown in voluntary systems related to sustainable housing.
(1) Specification based on the standards required by building codes
If the variables are within the scope of the country’s building codes, it is necessary for the system designers to search the building codes for the variables’ desired values. Building codes specify the “minimum standards” for constructed objects, in order to protect public health, safety, and general welfare [4]. If system designers consider that the standard value required by the building codes is insufficient for the desired value, they make an addition to the standard value, so as to suit the desired value. On the other hand, if they consider that the standard value is suitable to the desired value, they can use it as it is. In the latter case, the variable and its desired value can be omitted from the guidelines and checklist, for people who naturally conform to the building codes, which have legal force.
In fact, Tables 2 and 4 in Chapter 4 also include variables and their desired values, which have been specified based on the above approach. For example, when determining the desired value of “ratio of total window area to floor area in each living space,” a variable of “position and area of windows,” we have made an addition to the standard value required by the Building Standards Act of Japan, namely “1/7 (14.3%) or more,” and set the desired value at “20% or more.” Moreover, “JHPIS 1.1: Grade 2 or over,” the desired value of “resistance to earthquakes” of “framework,” has been originally determined, based on the standard required by the building code. To be concrete, “Grade 2” in this desired value means 1.25 times the strength of an earthquake stipulated in the Building Standards Act of Japan. In addition, “resistance to winds” and “resistance to snow load” are possible variables of “framework” that have been omitted from the tables, because the standards for these two required by the building code have been considered to be suitable to their desired values.
(2) Use of criteria shown in voluntary systems related to sustainable housing
The second approach is to utilize criteria shown in voluntary systems related to sustainable housing, which is especially important outside the scope of building codes. Various kinds of systems or methods for sustainable housing, including assessment and rating systems, standards, and guidelines, are used in many countries of the world [5]. Moreover, energy conservation standards or energy consumption labeling systems for appliances and equipment are also used in many countries [6]. Such voluntary systems or methods usually include criteria, such as grades, levels, classes, target figures, or guideline values. Accordingly, referring to such existing voluntary systems, system designers can select suitable criteria to the desired values of variables. In addition, even if there are not exactly suitable criteria, referring to relevant systems and criteria usually provide system designers with information closely related to the variables and their desired values and help them determine the desired values.
In Tables 2 and 4 of Chapter 4, a high percentage of variables’ desired values have been specified, based on this second approach. In particular, referring to the JHPIS and CASBEE for detached houses, we have selected appropriate grades or levels to the desired values of many variables. We have also used the long-life quality housing (LQH) certification criteria, when setting the desired values of several variables, including “total floor area.” When determining the variable of “appliances” and its desired value, we have utilized the energy-saving labeling system of Japan. Furthermore, consulting several accessible and universal design guidelines has led us to specify the desired values of variables related to universal design, such as “grade of steepness” (slope).
In short, system designers in each country can compile the guidelines and checklist, referring to compulsory and voluntary systems related to buildings and housing used in that country.
Theoretically, the methodology can be applied to various categories of human activities. In other words, in the control system for promoting sustainable home design (Figure 5 in Chapter 4), “homes” in the block of “controlled objects” can be replaced with other categories of human activities [2]. Possibility of such replacement depends on if the table of relationships or the “sustainable design guidelines” can be compiled or not [2].
It will be probably easy to apply it to other types of buildings besides the home, because the structure is similar to one another [2]. It is also possible in theory to apply it to other kinds of infrastructure, including roads and parks [2]. Moreover, we consider it possible to apply the methodology to more large-scale and complex objects, including the city and town, for they are also considered as the complex of material and spatial elements [2].
The case study has supported the effectiveness of the methodology for promoting sustainable housing design. However, we are necessary to conduct further case studies, applying it to both new and existing houses. We expect that the increase of application cases also leads to an increase in the reliability of the methodology and help it to be widely used [2].
The “sustainable design guidelines” and “sustainability checklist” need to be updated, as occasion requires. Such occasion is projected to occur due to several causes, for instance, changes in the natural and social environment, developments in related sciences, innovations in related technologies, and response to the results of case studies [2]. Moreover, through such revision or update processes, we are going to investigate how to revise them efficiently.
This study has demonstrated the methodology for sustainable housing design by applying control science, with a case study. The main point of the methodology is the control system for promoting sustainable housing design with the sustainable design guidelines and sustainability checklist. Utilizing this methodology, we have actually designed a home and built it. The evaluations of the home indicate that closely following the methodology leads to comprehensively achieving sustainable homes with high environmental performance.
Meanwhile, we have pointed out several characteristics of the methodology, in addition to comprehensiveness. First, the diagram of the control system itself is beneficial because it concisely shows the whole picture of the sustainable design processes on both new and existing homes. Second, the “sustainable design guidelines” and “sustainability checklist” are user-friendly since the material and spatial elements are equivalent to real parts of homes. Moreover, the “element – variable – desired value” structure in the guidelines and checklist is superior in “adaptability to regional differences” and “flexibility toward changes over time.”
In the twenty-first century, homes need to be transformed into those which contribute to deal with various issues, including climate change and financial problems due to aging population. Curbing the progress of climate change is a global challenge; therefore, mitigation measures have to be taken into homes all over the world. On the other hand, type and severity of impacts caused by climate change are different, depending on the region. Accordingly, appropriate adaptation measures need to be adopted in homes, in accordance with the predicted impacts in that region. Meanwhile, progressing aging population requires the inclusion of accessible and universal design into homes, in order to increase mobility of occupants and prevent injuries. Homes are used for a very long time; homes which are built or renovated now are expected to be used throughout the twenty-first century. Accordingly, such considerations toward sustainability need to be comprehensively taken into homes from the beginning.
Facing these circumstances, this user-friendly, comprehensive, adaptable, and flexible methodology is effective to promote sustainable housing design in various regions and countries. The guidelines and checklist shown in Tables 2 and 4 in Chapter 4 have been already compatible with climate change and aging population. These tables, which have been compiled to suit features in Japan, can be easily modified to fit features in other regions. Due to the same characteristic of this methodology, these tables can also be readily customized, so as to adapt to predicted impacts in each region caused by climate change. Hence, we expect that this methodology is used in various regions and countries, so as to facilitate sustainable home design.
The case study has successfully demonstrated the effects of the methodology on achieving sustainable homes. However, in order to confirm the effects, we need to conduct more case studies, applying it to both new and existing homes. Moreover, we will have to revise the “guidelines” and “checklist,” as the occasion arises. Through such revision processes, we are planning to examine how to revise them efficiently. Meanwhile, it is theoretically possible to apply this methodology to other categories of human activities, which are regarded as the complex of material and spatial elements. We are also aiming to apply this methodology to more complex and larger scale human activities, such as the city and town.
Yam plants belong to the genus
Although more than 600 cultivars of the tubers have been recorded [2], only a few are important as staple food in the tropics. These include white yam (
West Africa accounts for over 90% of world yam production with Nigeria, the largest single producer followed by Ghana and Cote d’Ivoire [5, 6]. In 2016, global yam production stood at 66 million metric tons (MT) with 86% of this coming from West Africa. In 2016, more than 90% (6.9 million ha) of the global area under yam cultivation was in West Africa, where the mean gross yield is 12 t/ha [5].
Worldwide annual consumption of yams is 18 million tons, with 15 million in West Africa. Annual consumption in West Africa is 61 kg/person/year [7]. Yams are consumed in the form of boiled, roasted, baked, or fried. Yam is an important staple food for many Ghanaians, accounting for 28% of total calorie sources in 2016 [8]. Per capita consumption of yam in Ghana increased from 83 kg/year 1995 to 160 kg/person/year in 2013, making yam the second most important calorie source after cassava in Ghana [8, 9]. Between 2005 and 2010, yam production in Ghana contributed about 16 percent to the country’s agricultural gross domestic product [6].
In Ghana, as in many other West African countries, the yam species of economic importance include
In West Africa, yams are a major source of income and have high cultural value. They are used in fertility and marriage ceremonies, and a festival is held annually to celebrate its harvest in most cultures across West Africa. In West Africa, yam plays key roles in food security, income generation, and the sociocultural life of at least 60 million people [7]. It also serves as source of foreign exchange to government. Ghana has been exporting substantial quantities of yam to regions such as Europe, America, and African countries such as Mali, Burkina Faso, and Niger. Although the second largest yam producer after Nigeria, Ghana is the leading exporter of yam in the world [6, 7], exporting approximately 21,000 metric tons of yams annually, a number that has been increasing over the last decade. In addition to the food and market values, yams play vital roles in traditional sociocultural rituals and religions that the ethnocentric attachment to the crop remains strong for some ethnic groups in Africa [10].
In a typical Ghanaian urban center, household food budget formed about 51% of the total household budget [11]. Yam constituted about 12% of household at-home food budget and 13% of its away-from-home food budget. The shares of food budget that households allocate to yam generally increase during the peak harvest season (August to December) and drops during lean season (June to July) across all urban centers in Ghana [11].
The top 10 yam-producing countries in the world are represented in Table 1. Together, they produced 72.3 million tons of yam in 2020, of which Africa accounted for about 99%. Most of the world’s production comes from West Africa representing 97%, with Nigeria alone producing about 69%, equaling to more than 50 million tons [5].
Rank | Country | Production (ha) | Production (tons) | Yield (tons/ha) |
---|---|---|---|---|
1 | Nigeria | 6,307,232 | 50,052,977 | 8 |
2 | Ghana | 468,433 | 8,532,731 | 18 |
3 | Cote D’Ivoire | 1,200,405 | 7,654,617 | 6 |
4 | Benin | 228,998 | 3,150,248 | 14 |
5 | Togo | 98,547 | 868,677 | 9 |
6 | Cameroon | 62,008 | 707,576 | 11 |
7 | Central African Republic | 58,533 | 491,960 | 8 |
8 | Chad | 47,784 | 458,054 | 9.6 |
9 | Papua New Guinea | 21,185 | 363,387 | 17 |
10 | Haiti | 9983 | 63,358 | 6 |
Yam production is regarded as a source of food security and employment to a lot of people in many areas where it is cultivated [12]. Yam is among the major cash and most consumed food crops in West African countries like Nigeria, Cote D’Ivoire, Ghana, Benin, and Togo. Its cultivation is very profitable despite high costs of production and price fluctuations in the markets [13]. Over 60% of people grow yams as a primary source of livelihood [6].
In Ghana, yam is produced in commercial quantities in all the regions, except the Greater Accra region, Central region, and Upper east region. The highest concentration of yam production is found in the central and northern Savannah portions of the country [6]. The northern region is the second leading yam producer after the Brong Ahafo region (Figure 1). The region produces about 2.3 million metric tons of yam annually [14].
Five top yam-producing regions of Ghana [
Even though, yam production is declining in some traditional yam-producing areas due to declining soil fertility, increasing pest pressures, and the high cost of labor [3, 15], production in Ghana has seen some steady increase over the past few years (Figure 2). Production grew by 19% between 2010 and 2020. This increase is mainly driven by growth in total hectares planted to yam, rather than growth in yam yields. The recent increases in production have often been attributed to the use of pesticides (herbicides) which allows small holder farmers to increase their area of cultivation [16]. The total yam production in Ghana in 2020 was 8,532,731 metric tons with mean gross yield of about 18 metric tons per ha [5].
Yam production in Ghana, 2010–2020 [
Yam is an annual or perennial vine and a climber with annual or perennial underground tubers. The life cycle of the yam plant consists of the following stages: propagules (true seed or tuber), emerging seedling or plantlet, mature plant, senescing plant, and dormant tubers. Yam has an annual vegetative system (Figure 3) composed of a root system (some extend throughout the upper layers of the soil, others consist of root hairs), a stem system, a foliar system, and a reproductive system [17].
Yam plants growing in the field, roots on tuber skin, and adventitious roots.
The root system generally consists of two categories of roots (Figure 3): the adventitious roots (appearing from the base of the stem) and roots arising from the skin of the tuber. The adventitious roots are usually about 3–6 mm thick and 1–3 m long and absorb nutrients and water. This type of roots extends throughout the upper layers of the soil and rarely branch out and emit few rootlets. The roots on the tuber are rarely more than few centimeters in length and are usually 1 or 2 mm thick [17]. These types of roots are not usually common on the tubers of the two yam varieties considered in this study (Laribako and Olodo).
The reproductive system consists of sexual components and a male or female inflorescence. The seed is flat, has a wing-like structure, and usually goes through a dormancy period of 3 to 4 months before germination can occur [3]. However, in Ghana and particularly in commercial production, yams are vegetatively propagated using the basal nodal region of the tuber, as flowering is rare.
The tuber, the economically important part of the yam plant, is rich in carbohydrates and contains modest amounts of mineral matter (calcium and iron), vitamin B, vitamin C, and crude fiber [3]. The plant usually produces a single annual tuber, which is 20–40 cm long and weighs from two to a dozen kilograms, depending on cultivar and growing conditions. The body can be elongated or spherical with a white, yellow, or purple flesh [18].
Yams are essentially tropical crops. Their growth is severely restricted at temperatures below 20°C. In general, they require temperatures of 25–30°C for normal growth to occur. Closely linked to temperature for optimal growth of the yam plant is light. It has been observed that the length of the day plays an important role in tuber formation. Short days tend to favor tuber formation and tuber growth, while long days favor vine growth. Though the influence of light intensity on yam growth and productivity has not been fully investigated, several points suggest that it is not a shade-loving plant. It requires and tolerates high intensities of sunlight to be maximally productive [1]. Because of this, in the Nanumba traditional area of Ghana, yam farmers after land preparation will usually devote substantial amount of their time to burn down or prune big trees on their farms before planting.
Yams thrive best when they receive sufficient moisture (about 1000 mm rainfall) well distributed throughout the growing cycle [3]. Since most yams require 7–9 months from planting to harvesting, they do best in areas where the rainy season is relatively long and where there are fewer than three or four rainless months in a year. Even though, the yam plant can survive droughts, they usually will give disappointing harvest. Hence, if yam is to be grown in an area where the dry season is longer, then supplementary irrigation must be provided [1]. In Ghana, the rain starts in April and ends in October, thereby providing the growing yam plants with 5 months continuous rain. A minimum of 1000 mm of water is required for the optimum growth [19].
Yam like other crops requires soils of high fertility in order do well. For this reason, in traditional yam cultivation, it is grown on fertile forest soils as the first crop after clearing large trees or after a long term of fallowing [3, 17]. They are also cultivated in sandier savannah types of soils in the northern parts of West African [3]. Soils in the Nanumba traditional area are generally loamy in structure with good organic matter content and good water-holding capacity. This explains why the area is good for yam production. Soil structure has an impact on harvesting and ultimately on the quality of the tuber as loamy soils make harvesting easy with less bruises and clayey soils make harvesting difficult with lots of bruises on the yam (Rahaman, personal communication).
Yam is propagated from seed tubers or sections of the tuber. The use of true seeds as propagules is restricted to research stations, mainly in crop improvement programs. Traditionally, farmers obtain seed tubers in different ways. They may select small tubers (e.g. 300–500 g) from each harvest, use tubers from the second harvest of early maturing varieties, use small tubers from varieties that produce multiple tubers per stand, or cut ware tubers into pieces [3, 20]. Yam is sometimes planted alone, but it is more often intercropped with maize, cassava, rice, or other crops such as the legumes [3, 15]. Depending on the type of planting material, species, and location, effective duration of crop growth ranges from 6 to 12 months, calculated from the time of seed emergence until senescence of the leaves [19].
Yam is cultivated either on mounds or on ridges, and the growing plants can be staked or allowed to spread on the ground without stakes, especially in the savanna agro-ecological zone. Though staking may increase tuber yield, depending on the cultivar, the cost of stakes, the labor demand for their placement, and the environmental damage associated with their use may render this practice uneconomical [21, 22].
In Ghana, as in many other yam-producing countries in West Africa, yam production involves seven main processes. These include land preparation, planting, mulching, staking, weeding, harvesting, and storage. Fertilizer application on yam is rarely practiced at the farm level in Ghana.
Traditionally, land preparation in yam production is done by first clearing the land either manually with the use of a hoe and a cutlass, or the use of a tractor or bullocks [3]. However, with the modernization of yam farming, the use of herbicides has been adopted for land clearing in some yam-growing communities. In the case of manual land clearing and the use of herbicides, 2–4 weeks are allowed for the stubble to dry so as to enable the farmer to burn them and raise mounds. In the case of tractor ploughing, the farmer will usually go through the ploughed land and further clear grasses that are left under trees after which a second ploughing will be done before mounds are raised. Even though, it is said that yam can be grown on either mounds or ridges [3, 22], ridging is not yet practiced in the Nanumba traditional area of Ghana and mounding is done manually by the use of a hoe. In forested areas or in the savannah woodlands where there are substantial tree populations, the land clearing process also involves the burning or pruning of trees.
The use of herbicides for land clearing in yam farming is catching up very fast with farmers in the northern savannah areas of Ghana, especially farmers in the Nanumba traditional area, since it makes subsequent land preparation operations such as mounding easy and also gives them a better tuber yield (Rahaman, personal communication).
In the Nanumba traditional area of Ghana, yam is usually planted from December to February, the peak of the dry season. As a result of this, the planting operation is usually accompanied by capping (mulching) the yam mounds with some grass or leaves (Figure 4) to protect the planted sett from excessive heat and desiccation [1, 3, 17]. However, farmers who are not able to plant around this time would usually wait until the rain starts in April/May.
Yam planted and mulched on manually prepared mounds [
The time of planting yam depends on a number of factors, including the onset of the rains, the type of cultivars, the local ecological conditions, and the demand. For example, many
Staking is one of the yam farmer’s main concerns [17, 21], since it is becoming increasingly difficult to obtain stakes throughout the yam-growing zones, especially in the dry savannah regions of West Africa. In its rudimentary form as it is practiced by yam farmers in the Nanumba traditional area of Ghana, stakes are obtained by cutting down young growing trees or cutting of the branches of bigger trees. Sometimes, trees that are burnt in the process of land preparation also serve as stakes. The stakes can be of different sizes (Figure 5) ranging from 1 to 4 m. The smaller ones are usually planted on the yam mound, while the bigger stakes are placed between yam mounds so that several plants can climb on it.
Staked yam farm.
Tropical forests generally have high natural coppice rates, but these are reduced when trees are cut too close to the ground. It is suggested that ideally cuts should be made at least 45 cm from the ground to maximize regrowth. However, in an effort to get as much length from a sapling, yam stick cutters often cut sticks almost at ground level [23].
Weeds are one of the serious challenges confronting yam production throughout the world [2]. The climbing growth habit of the plant coupled with its inability to shade the ground completely at any stage of its growth and development makes it very susceptible to weed interference [3]. In a study of Akobundu [24], it was observed that the critical period of weed interference in white yam is between the 8th and 16th week after planting. Proper weed management is necessary to obtain optimum yam yields. In general, a minimum of three to four weeding activities between planting and harvesting are necessary to minimize yield reduction. It is reported that weeds can cause yield loss in yam up to 90%. In most of the humid tropics, repeated hand weeding is a common feature of yam production. However, the commercialization of agriculture and high population growth with attendant increase in demand for yams, in the absence of adequate labor [3], have created the need for the introduction of efficient and nonlabor-intensive methods of yam production [24].
In the yam-growing areas of Ghana, farmers usually go into the farm 1 month after planting with their hoe and cutlass to clear the farm of shrubs and other broad leaf weeds that have appeared. After this first weeding, the farmer can carry out three other weeding activities before harvesting in the case of manual weeding and one weeding in the case of chemical control.
In recent times, yam farmers in Ghana who are mostly located in rural areas adopt chemical weed control on yam. This is due to the dwindling labor force in the rural communities as a result of rural-urban migration of the youth in search of white collar jobs [25]. It can also be partly attributed to the expansion of farm sizes due to decreasing soil fertility and the commercialization of yam farming. However, whether a farmer uses chemical or manual weed control, the hoe is still employed, because the use of the hoe loosens the soil up to enhance aeration and water percolation.
Time for yam harvesting varies and may be spread out over several months in almost all regions due to the wide range of species and cultivars. For example,
The first harvesting is done at a time when the plant has fully flowered (usually 6 months after planting) and the vines are about to cease growth with some of the bottom leaves turning yellow (Figure 6), that is usually around August and September. After this first harvest, the yam plant will regenerate and grow for some time and wither and finally dry up. This allows for the production of seed yam which is harvested in the second harvest period (December to January) together with late yam varieties like
Harvesting of yam.
Early harvesting is done by the use of either a cutlass [2] or a sharp-ended stick where the mound is carefully cut open and the tuber is severed from the vine at the point below the base of the vine after which the mound is neatly covered to allow regenerative growth for seed tubers (Figure 6). On the other hand, late harvesting is done by the use of a hoe and cutlass, where the withered plant is cut off and half of the mound destroyed in order to remove the ware tuber or the seed tuber. In either situation, care is needed to minimize damage or bruises that lead to rot in tubers and a decrease in market value of the yam [6].
Yam as a tropical tuber crop has a relatively long shelf life (6–8 months) compared to other tropical fresh produce [3, 27]. This explains why, as a staple food, yam is available all year round for consumers. However, this long storability of yam notwithstanding, tubers are often damaged during harvesting and after harvesting, and this can lead to postharvest losses. After harvesting, yam can be stored either by adopting traditional or modern methods of storage [1, 12, 17]. The traditional system of yam storage varies among the different yam-producing countries of the world [27]. In Ghana, just as observed in other West African countries [27], yams can be stored by leaving them in the ground until they are needed for food or for sale. This system however exposes the yam tuber to attack by pests such as termites and rodents and harvesting also becomes difficult when the ground becomes hard during the dry season, resulting in tuber breakage and bruises which predispose the tubers to pathogens leading to loss of tubers in storage [28, 29]. Also, with this system, when there is heavy rain, the tubers may become rotten. The other traditional methods of yam storage include wooden platforms, cool and well-ventilated rooms, yam barns, heaping and covering with dry grass under trees, stored in a thatched shed, and Silo (burying in the soil) [27, 28, 30, 31]. The commonest traditional method of yam storage in Ghana is storage in the yam bam [32, 33, 34]. The modern methods on the other hand include chemical treatments (e.g. fungicides), storage in a cold room, and refrigeration; however, the method of cold storage is hardly practiced by farmers in West Africa [12, 28].
The efficacy of tuber storage structures for preserving yams until they are used is influenced by the cultivars, environmental conditions such as relative humidity and temperature, the physical condition of the tubers at the beginning of storage, and the effectiveness to exclude vermin such as rodents [27, 30, 32]. Traditional storage methods therefore vary according to ecology and the volume of yam produced [2].
Due to the economic circumstances in the yam-growing areas in Ghana and the Nanumba traditional area of Ghana in particular, farmers store yam through the traditional methods (Figure 7). In this traditional area, after harvest, farmers will usually burry the tubers in the soil or keep them under the shade of a tree and cover them with dry vines of yam or grass. They can also keep them in constructed barns on the farm or in the house or keep them in well-ventilated rooms. The latter practice is hardly done by farmers, but rather a common practice of yam traders (Imoro, personal communication).
Yam storage in the field.
Storage is an important element within the yam production chain which, when not properly done, can lead to high postharvest losses leading to low incomes for farmers and food insecurity. Onwueme [1] and Ravi et al., [27] respectively observed that shading, ventilation, and constant inspection are three essential elements for good yam storage in a barn. They asserted that ventilation serves two purposes, i.e. preventing the buildup of high humidity which favors rotting and preventing tubers from heating up owing to their own respiratory activities.
Postharvest losses for yam in Ghana are as high as 24 percent of production, despite the Ministry of Agriculture’s goal to reduce these losses to only 12 percent [35, 36]. The major causes of postharvest losses are weight loss due to evapotranspiration intensified by sprouting, rotting due to fungal and bacterial pathogens, and insect infestation [35, 37].
In spite of the importance of yam as a food security and cash crop, yam farmers in Ghana suffer serious challenges in the production process. Among these production challenges are field and storage pests and diseases and weed burden [37, 38, 39, 40].
Yams are infested by a broad taxonomic diversity of insect pests [41]. In a study of Braimah et al. [42], field and storage pests of yam in Ghana are identified. These pests (Table 2) cause significant losses to tubers both in the field and in storage.
Pest | Scientific name | Order | Categorization |
---|---|---|---|
Termites | Isoptera | Field | |
Millipedes | Callipodida | Field | |
Tuber beetles | Coleoptera | Field and storage | |
Leaf beetles | Coleoptera | Field | |
Mealybugs | Hemiptera | Storage | |
Scale insects | Hemiptera | Field and storage | |
Crickets | Orthoptera | Field | |
Nematodes | Nematoda | Field | |
Field and storage pest of yam in Ghana.
Yam in Ghana is attacked by a couple of diseases both in the field and in storage. However, the common diseases are those caused by fungi (Table 3). Other diseases affecting yam in Ghana are bacterial and viral diseases [37].
Disease | Causal organism | Type | Categorization |
---|---|---|---|
Rots | Fungus | Storage | |
Storage | |||
Storage | |||
Storage | |||
Field | |||
Storage | |||
Storage | |||
Storage | |||
Storage | |||
Storage | |||
Bacteria | Field and Storage | ||
Nematode | Field | ||
Field | |||
Galling of tubers | Nematode | Field | |
Yam mosaic | Virus | Field | |
Field |
Diseases affecting yam in Ghana.
Yam is prone to infection right from the seedling stage through to harvesting and even after harvesting (in storage); hence, diseases of yam can be grouped into field and storage diseases. The field and storage diseases are many and varied. While Aboagye-Nuamah et al. [37] found that
Tuber rots through microbial attack are an important cause of postharvest loss in yam throughout the tropics [33]. Rot from microbial infection of healthy tubers reduces their table quality and renders them unappealing to consumers, as it leads to total loss of tuber carbohydrates by transforming it into inedible colored mass. It is reported that postharvest losses in yam due to tuber rots can be as high as between 20 and 60% [31, 45, 46]. The rots are of different types, including soft rots, dry rots, and wet rots [29, 45, 47, 48].
Due to the importance of microbial tuber rots in yam, studies have been conducted to identify the causal organisms. In Ghana, Cornelius [45] in a survey identified some fungal, bacterial, and nematode species (Table 3) to be responsible for yam tuber rots. In a related study, Aboagye-Nuamah et al. [37] confirmed the fungal and bacterial species reported by Cornelius [45] to be the cause of yam tuber rots. Subsequently, Asare-Bediako et al. [49] in a study to identify microorganisms causing rot in white yam found
Even though there have been reports of the use of insecticides such as pirimiphos-methyl (Actellic 2% Dust) [52] leading to significant reduction in fungal infections and physical damage to yam tubers, yam farmers in the Nanumba traditional area currently do not treat yam on the field and after harvest with chemicals. They rather adopt crop rotation, bush fallow, and use of healthy planting materials. The use of chemical insecticides as practiced in the Delta State in Nigeria [53, 54] can indirectly reduce the incidence of rots in the yam tuber caused by fungi, because physical damage to the yam tuber, either mechanically or by insects attack, can serve as conduit for microbial infections [28, 30, 31].
The common weeds found on yam farms in Ghana can be seen in Table 4. They belong to three groups, i.e. the dicotyledons, monocotyledons, and the parasites [38].
Weed group | Name |
---|---|
Monocotyledons | |
Dicotyledons | |
Parasites |
Weeds associated with yam cultivation in Ghana.
In a study by Akobundu [24], it was observed that annual weeds caused a tuber yield reduction of about 54% and 90%, respectively, when the period of weed interference lasted 3 and 4 months after planting.
Yam, sweet in flavor, is consumed as boiled yam (as cooked vegetable) or fufu or fried in oil (Figure 8) and then consumed. It is often pounded into a dough-like paste after boiling and is consumed with soup [3]. It is also processed into flour for use in the preparation of the paste. The tuber is the edible part of the yam plant with high carbohydrate content and low in fat and proteins and provides a good source of energy. Yam is an important source of minerals such as calcium, phosphorus, iron, carbohydrates, and vitamins such as riboflavin, thiamin, vitamin B, and vitamin C [55, 56]. Yam has some inherent characteristics which make it attractive and keep it in a high demand. First and foremost, it is rich in carbohydrates, especially starch; consequently, it has a multiplicity of end uses. Secondly, it is available all year round, making it preferable to other seasonal crops [13].
Prepared yam dishes of fufu, boiled yam, and fried yam.
Yam contains products such as alkaloids (saponin and sapogenin) and proteins (dioscorin and diosgenin) which can cause side effects in humans and animals such as inflammations, allergic reactions, kidney problems, and interference with the metabolic system [57, 58]. However, these same properties of the yam plant are exploited in medicine for the treatment and management of conditions such as allergies, metabolic disorders, hypertension, inflammations, and hormonal irregularities [58, 59, 60]. Yam has been used in traditional medicine in Africa and among the Chinese and other Asiatic people to treat diseases like diabetes, to increase coronary circulation, and to prevent hypercholesterolemia [55, 61, 62]. Although the industrial use potential of yam has not been fully exploited, its use as an industrial starch has been established as the quality of some of the species is able to provide as much starch as in cereals [11, 63, 64].
In recent times, efforts have been made by the scientific community to investigate the suitability of yam to be fried into chips like French fries. In a study to investigate the effect of blanching and frying on the textural profile and appearance of yam for French fries [9], it was found that yam fries with desirable texture and color attributes can be produced with
The importance of yam in the economy of some producing areas appears to be declining due partly to competition from other crops like cassava in Nigeria and taro in the South Pacific. However, in Ghana, the contribution of yam to the economy by way of meeting household food needs and foreign exchange earnings through exports has been growing [11].
Harvested yams in most communities are mostly for household consumption with only 16.4% of farmers selling more than half of their harvested yam [26]. Yam tubers meant for sale are mostly sold to merchants in local markets and also directly to ordinary people and food vendors in towns. These merchants come from other regions and move from village to village to purchase tubers directly from farmers. In the Nanumba traditional area of the northern region of Ghana, merchants come from Accra and Kumasi in Southern Ghana to buy yam [65]. This practice conforms with what happens in the Niger State of Nigeria where merchants come from Ibadan and Ilorin in southern Nigeria to buy yam [26].
In Ghana, yam is generally traded in its original state and is not processed into a secondary product. Traders and chop bar owners (small restaurants) often buy yam to sell or prepare it for consumers directly. Yam for the export market is also not processed, but is treated, wrapped in paper, and packed in 20-kg boxes before it is shipped [37].
About a decade ago, the UK was the leading importer (49%) of Ghana yam export, followed by the Netherlands and the USA [6]. Since then, the trend has changed dramatically with the USA now leading the chat. In 2017, Ghana exported a total value of USD 38,393.00 worth of yam to 10 top importing countries of which the USA took 35%, followed by the UK and Belgium of 34% and 9%, respectively [66] (Figure 9). The large volumes of yam exported to these destinations are largely due to the high demand for yam by Ghanaians and other West Africans residing in these countries.
Share of Ghana yam export by importing countries.
All over the world, there are concerns about pesticide residues resulting from the use of pesticides on crops [67]. For this reason, governments and especially in the EU allow pesticides to enter their respective countries as long as they are used in line with the law and the guidelines controlling their use.
In Ghana, public concerns are high about the use of pesticides by Ghanaian farmers and its attendant food safety and human health issues. This has led to the conduct of pesticides residue monitoring studies to assess the levels of pesticides in various food items. In a study by Asiedu [68] to determine pesticides residues in lettuce, garden egg, pineapple, and mango in three regions of Ghana, it was found that some market fruits and vegetables contained different types of pesticides of which chlorpyrifos (an organophosphate) and cypermethrin (a synthetic pyrethroid) were the most common ones. In a study by Bempah & Donkor [69] to assess the concentration of pesticides residues in fruits and vegetables from selected markets in Kumasi in the Ashanti region, it was found that 19% of the samples contained pesticides residues above the maximum residue level (MRL) with the health risk analysis further revealing that the pesticides endrin had exceeded the reference dose in vegetables, thereby suggesting a great potential for systematic poisoning in children that are considered as the most vulnerable population subgroup.
There is limited literature on pesticides residues in yam in contrast to other root and tuber crops in developing countries [70, 71]. This is partly because the crop is grown and consumed mostly in the developing world where there is limited scientific expertise and resources to set residue limits and to monitor them. In a study of Adeyeye and Osibanjo [70], 55% of yam samples from Nigerian markets were contaminated with one or more organochlorine pesticides (aldrin, dieldrin, HCH, and DDT). In a monitoring program by the “UK pesticides residue committee,” to check whether pesticides residues in food and drink are above the maximum residue levels (MRLs), it was found that yam was among the food commodities with pesticides residues exceeding the MRLs [72]. Out of the 52 yam samples analyzed, 9 samples contained residues at or below the MRL, 11 samples contained residues above the MRL, and 13 samples contained more than one residue. The report observed further that as in previous years relatively high numbers of samples with residues over the MRL were found in the specialty vegetables, okra and yam. The yam samples used in this monitoring study originated from Ghana, Brazil, and Jordan. The samples from Ghana had residue levels of 0.2–0.3 mg/kg carbendazim (MRL = 0.1 mg/kg) and 0.4 mg/kg tebuconazole (MRL = 0.02 mg/kg). Since MRLs are not safety limits, risk assessment were carried out with the monitoring results which showed that the residues found in the yam will be unlikely to have adverse effects on health [72]. Similarly, in the studies of Wumbei et al., [73, 74] to investigate pesticides residues in yam, 12 pesticides, including five insecticides (cadusafos, fenitrothion, imidacloprid, profenofos, and propoxur), four fungicides (carbendazim, fenpropimorph, metalaxyl, and propiconazole), and three herbicides (bentazone, glyphosate, and pendimethalin) were detected. However, when consumption risk assessment was carried out, it was revealed that there was no risk of dietary intake of these pesticides in yam under the deterministic approach (Table 5) and simple distribution approach (Table 6), but there was intake risk in about 10% of the study population to fenpropimorph and fenitrothion under the probabilistic (upper bound scenario) approach (Table 7) [75].
Residues (mg/kg) | ||||||
---|---|---|---|---|---|---|
Fenitrothion | Fenpropimorph | |||||
Mean | 0.0043 | 0.0003 | ||||
Median | 0.0023 | 0.0002 | ||||
P75 | 0.0069 | 0.0002 | ||||
P90 | 0.0069 | 0.0006 | ||||
P95 | 0.0079 | 0.0007 | ||||
P97.5 | 0.0097 | 0.0013 | ||||
P99 | 0.0144 | 0.0031 | ||||
Yam consumption (kg/kgBW/day) | ||||||
Mean | Median | P75 | P90 | P95 | P97.5 | P99 |
0.006 | 0.006 | 0.008 | 0.009 | 0.01 | 0.011 | 0.013 |
Estimated daily intake (EDI) (mg/kgBW/day) | ||||||
Fenitrothion | Fenpropimorph | |||||
Mean | 0.000026 | 0.000002 | ||||
Median | 0.000014 | 0.000001 | ||||
P75 | 0.000055 | 0.000002 | ||||
P90 | 0.000062 | 0.000006 | ||||
P95 | 0.000082 | 0.000007 | ||||
P97.5 | 0.000110 | 0.000014 | ||||
P99 | 0.000187 | 0.000040 | ||||
Residues (mg/kg) | |||||
---|---|---|---|---|---|
Cadusafos | Carbendazim | Glyphosate | Imidacloprid | Metalaxyl | |
0.0005 | 0.0007 | 0.12 | 0.0007 | 0.0009 | |
Statistical dist. of yam consumption (kg/kgBW/day) = Loglogistic (−0.017192; 0.02288; 14,635) | |||||
EDI (mg/kgBW/day) | |||||
Cadusafos | Carbendazim | Glyphosate | Imidacloprid | Metalaxyl | |
Mean | 0.0000029 | 0.0000041 | 0.00070 | 0.0000041 | 0.0000053 |
Median | 0.0000028 | 0.0000039 | 0.00068 | 0.0000039 | 0.0000051 |
P75 | 0.0000037 | 0.0000052 | 0.00089 | 0.0000052 | 0.0000067 |
P90 | 0.0000047 | 0.0000066 | 0.00113 | 0.0000066 | 0.0000084 |
P95 | 0.0000054 | 0.0000075 | 0.00129 | 0.0000075 | 0.0000097 |
P97.5 | 0.0000061 | 0.0000085 | 0.00146 | 0.0000085 | 0.000011 |
P99 | 0.0000071 | 0.00001 | 0.00169 | 0.00001 | 0.000013 |
ADI (mg/kgBW/day) | 0.0004 | 0.02 | 0.5 | 0.06 | 0.08 |
Residues (mg/kg) | |||||
Pendimethalin | Profenofos | Propiconazole | Propoxur | Bentazone | |
0.0003 | 0.0004 | 0.0002 | 0.0004 | 0.0007 | |
EDI (mg/kgBW/day) | |||||
Pendimethalin | Profenofos | Propiconazole | Propoxur | Bentazone | |
Mean | 0.0000018 | 0.0000023 | 0.0000012 | 0.0000023 | 0.0000041 |
Median | 0.0000017 | 0.0000022 | 0.0000011 | 0.0000022 | 0.0000039 |
P75 | 0.0000022 | 0.0000029 | 0.0000015 | 0.0000029 | 0.0000052 |
P90 | 0.0000028 | 0.0000037 | 0.0000019 | 0.0000037 | 0.0000066 |
P95 | 0.0000032 | 0.0000043 | 0.0000021 | 0.0000043 | 0.0000075 |
P97.5 | 0.0000036 | 0.0000049 | 0.0000024 | 0.0000049 | 0.0000085 |
P99 | 0.0000042 | 0.0000056 | 0.0000028 | 0.0000056 | 0.00001 |
Statistical distributions of residue and consumption data | ||||
---|---|---|---|---|
Fenpropimorph (mg/kg) | Fenitrothion (mg/kg) | Yam consumption (kg/kgBW/day) | ||
LB (0), UB (0.0035) | LB (0) UB (0.0115) | Loglogistic (−0.017192; 0.02288; 14,635) | ||
EDI (mg/kgBW/Day) | ||||
Percentile | Fenpropimorph | Fenitrothion | ||
Lower bound | Upper bound | Lower bound | Upper bound | |
Mean | 0.000008 | 0.00058 | 0.000024 | 0.0012 |
Median | 0.000000 | 0.00001 | 0.000000 | 0.0001 |
P75 | 0.000000 | 0.00002 | 0.000043 | 0.0022 |
P90 | 0.000006 | 0.0023 | 0.000076 | 0.0042 |
P95 | 0.000011 | 0.0051 | 0.0001 | 0.0052 |
P97.5 | 0.000019 | 0.0066 | 0.00013 | 0.0060 |
P99 | 0.000044 | 0.0082 | 0.0002 | 0.0071 |
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This contribution surveys the state of the art of these applications, with special emphasis on their possibilities and limitations.",book:{id:"6768",slug:"cosmic-rays",title:"Cosmic Rays",fullTitle:"Cosmic Rays"},signatures:"Paola La Rocca, Domenico Lo Presti and Francesco Riggi",authors:[{id:"18197",title:"Dr.",name:"Francesco",middleName:null,surname:"Riggi",slug:"francesco-riggi",fullName:"Francesco Riggi"},{id:"18200",title:"Dr.",name:"Paola",middleName:null,surname:"La Rocca",slug:"paola-la-rocca",fullName:"Paola La Rocca"},{id:"243971",title:"Dr.",name:"Domenico",middleName:null,surname:"Lo Presti",slug:"domenico-lo-presti",fullName:"Domenico Lo Presti"}]},{id:"54705",doi:"10.5772/68116",title:"The Impact of Baryons on the Large-Scale Structure of the Universe",slug:"the-impact-of-baryons-on-the-large-scale-structure-of-the-universe",totalDownloads:1472,totalCrossrefCites:4,totalDimensionsCites:4,abstract:"Numerical simulations play an important role in current astronomy researches. Previous dark-matter-only simulations have represented the large-scale structure of the Universe. However, nowadays, hydro-dynamical simulations with baryonic models, which can directly present realistic galaxies, may twist these results from dark-matter-only simulations. In this chapter, we mainly focus on these three statistical methods: power spectrum, two-point correlation function and halo mass function, which are normally used to characterize the large-scale structure of the Universe. We review how these baryon processes influence the cosmology structures from very large scale to quasi-linear and non-linear scales by comparing dark-matter-only simulations with their hydro-dynamical counterparts. At last, we make a brief discussion on the impacts coming from different baryon models and simulation codes.",book:{id:"5918",slug:"trends-in-modern-cosmology",title:"Trends in Modern Cosmology",fullTitle:"Trends in Modern Cosmology"},signatures:"Weiguang Cui and Youcai Zhang",authors:[{id:"199688",title:"Dr.",name:"Weiguang",middleName:null,surname:"Cui",slug:"weiguang-cui",fullName:"Weiguang Cui"},{id:"205491",title:"Dr.",name:"Youcai",middleName:null,surname:"Zhang",slug:"youcai-zhang",fullName:"Youcai Zhang"}]},{id:"54580",doi:"10.5772/67976",title:"The Importance of Cosmology in Culture: Contexts and Consequences",slug:"the-importance-of-cosmology-in-culture-contexts-and-consequences",totalDownloads:3309,totalCrossrefCites:2,totalDimensionsCites:2,abstract:"Scientific cosmology is the study of the universe through astronomy and physics. However, cosmology also has a significant cultural impact. People construct anthropological cosmologies (notions about the way the world works), drawing in scientific theories in order to construct models for activities in disciplines, such as politics and psychology. In addition, the arts (literature, film and painting, for example) comment on cosmological ideas and use them to develop plot lines and content. This chapter illustrates examples of such work, arguing that scientific cosmology should be understood as a significant cultural influence.",book:{id:"5918",slug:"trends-in-modern-cosmology",title:"Trends in Modern Cosmology",fullTitle:"Trends in Modern Cosmology"},signatures:"Nicholas Campion",authors:[{id:"200410",title:"Dr.",name:"Nicholas",middleName:null,surname:"Campion",slug:"nicholas-campion",fullName:"Nicholas Campion"}]},{id:"60664",doi:"10.5772/intechopen.75877",title:"Galactic Cosmic Rays from 1 MeV to 1 GeV as Measured by Voyager beyond the Heliopause",slug:"galactic-cosmic-rays-from-1-mev-to-1-gev-as-measured-by-voyager-beyond-the-heliopause",totalDownloads:1241,totalCrossrefCites:1,totalDimensionsCites:1,abstract:"Voyager 1 has now been beyond the heliopause for over 5 years since its seminal crossing of this boundary in August of 2012. During its epic 40 year journey of ~122 AU out to this boundary and beyond this spacecraft has passed through several regions of the heliosphere including the heliosheath of extent ~30 AU just inside the heliopause (HP), where extremely large and variable intensities of protons, helium and oxygen nuclei as well as electrons between 1 and 100 MeV were observed. Then, suddenly these particles completely vanished and new and completely different spectra of particles between 1 MeV up to ~1 GeV and beyond, instantly recognizable as those for galactic cosmic rays were observed. These spectra and intensities at all energies have remained constant to within ±1% for 5 years corresponding to 20 AU beyond the HP.",book:{id:"6768",slug:"cosmic-rays",title:"Cosmic Rays",fullTitle:"Cosmic Rays"},signatures:"William R. Webber",authors:[{id:"114311",title:"Prof.",name:"William R",middleName:null,surname:"Webber",slug:"william-r-webber",fullName:"William R Webber"}]}],mostDownloadedChaptersLast30Days:[{id:"54580",title:"The Importance of Cosmology in Culture: Contexts and Consequences",slug:"the-importance-of-cosmology-in-culture-contexts-and-consequences",totalDownloads:3316,totalCrossrefCites:2,totalDimensionsCites:2,abstract:"Scientific cosmology is the study of the universe through astronomy and physics. However, cosmology also has a significant cultural impact. People construct anthropological cosmologies (notions about the way the world works), drawing in scientific theories in order to construct models for activities in disciplines, such as politics and psychology. In addition, the arts (literature, film and painting, for example) comment on cosmological ideas and use them to develop plot lines and content. This chapter illustrates examples of such work, arguing that scientific cosmology should be understood as a significant cultural influence.",book:{id:"5918",slug:"trends-in-modern-cosmology",title:"Trends in Modern Cosmology",fullTitle:"Trends in Modern Cosmology"},signatures:"Nicholas Campion",authors:[{id:"200410",title:"Dr.",name:"Nicholas",middleName:null,surname:"Campion",slug:"nicholas-campion",fullName:"Nicholas Campion"}]},{id:"55416",title:"Constraining the Parameters of a Model for Cold Dark Matter",slug:"constraining-the-parameters-of-a-model-for-cold-dark-matter",totalDownloads:1292,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"This chapter aims at reviewing how modeling cold dark matter as weakly interacting massive particles (WIMPs) gets increasingly constrained as models have to face stringent cosmological and phenomenological experimental results as well as internal theoretical requirements like those coming from a renormalization-group analysis. The review is based on the work done on a two-singlet extension of the Standard Model of elementary particles. We conclude that the model stays viable in physically meaningful regions that soon will be probed by direct-detection experiments.",book:{id:"5918",slug:"trends-in-modern-cosmology",title:"Trends in Modern Cosmology",fullTitle:"Trends in Modern Cosmology"},signatures:"Abdessamad Abada and Salah Nasri",authors:[{id:"54894",title:"Prof.",name:"Salah",middleName:null,surname:"Nasri",slug:"salah-nasri",fullName:"Salah Nasri"},{id:"61340",title:"Dr.",name:"Abdessamad",middleName:null,surname:"Abada",slug:"abdessamad-abada",fullName:"Abdessamad Abada"}]},{id:"69434",title:"Applications of the Abelian Vortex Model to Cosmic Strings and the Universe Evolution",slug:"applications-of-the-abelian-vortex-model-to-cosmic-strings-and-the-universe-evolution",totalDownloads:794,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"Due to the wide range of applications and effects of the Abelian vortex model of Nielsen and Olesen in the many areas of physics, ranging from condensed matter to astrophysical effects, some work in the literature is necessary to approach this topic in a succinct form that the undergraduate student in both physics and related areas has the possibility to know and understand. The mechanisms associated with this vortex model indicate him as a strong candidate for the source for the topological defects proposed by Vilenkin.",book:{id:"7357",slug:"new-ideas-concerning-black-holes-and-the-universe",title:"New Ideas Concerning Black Holes and the Universe",fullTitle:"New Ideas Concerning Black Holes and the Universe"},signatures:"Mikael Souto Maior de Sousa and Anderson Alves de Lima",authors:[{id:"274390",title:"Dr.",name:"Mikael Souto",middleName:null,surname:"Maior De Sousa",slug:"mikael-souto-maior-de-sousa",fullName:"Mikael Souto Maior De Sousa"},{id:"284103",title:"Dr.",name:"Anderson",middleName:null,surname:"Alves De Lima",slug:"anderson-alves-de-lima",fullName:"Anderson Alves De Lima"}]},{id:"54849",title:"Superfluid Quantum Space and Evolution of the Universe",slug:"superfluid-quantum-space-and-evolution-of-the-universe",totalDownloads:1813,totalCrossrefCites:5,totalDimensionsCites:6,abstract:"We assume that dark energy and dark matter filling up the whole cosmic space behave as a special superfluid, here named “superfluid quantum space.” We analyze the relationship between intrinsic pressure of SQS (dark energy's repulsive force) and gravity, described as an inflow of dark energy into massive particles, causing a negative pressure gradient around massive bodies. Since no superfluid has exact zero viscosity, we analyze the consequences of SQS’s viscosity on light propagation, and we show that a static Universe could be possible, by solving a modified Navier-Stokes equation. Indeed, Hubble’s law may actually refer to tired light, though described as energy loss due to SQS’s nonzero viscosity instead of Compton scattering, bypassing known historical problems concerning tired light. We see that SQS’s viscosity may also account for the Pioneer anomaly. Our evaluation gives a magnitude of the anomalous acceleration aP = −HΛc = −8.785°10−10 ms−2. Here, HΛ is the Hubble parameter loaded by the cosmological constant Λ. Furthermore, the vorticity equation stemming from the modified Navier-Stokes equation gives a solution for flat profile of the orbital speed of spiral galaxies and discloses what one might call a breathing of galaxies due to energy exchange between the galactic vortex and dark energy.",book:{id:"5918",slug:"trends-in-modern-cosmology",title:"Trends in Modern Cosmology",fullTitle:"Trends in Modern Cosmology"},signatures:"Valeriy I. Sbitnev and Marco Fedi",authors:[{id:"93881",title:"Dr.",name:"Valeriy",middleName:null,surname:"Sbitnev",slug:"valeriy-sbitnev",fullName:"Valeriy Sbitnev"},{id:"200600",title:"Dr.",name:"Marco",middleName:null,surname:"Fedi",slug:"marco-fedi",fullName:"Marco Fedi"}]},{id:"60002",title:"Cosmic Ray Muons as Penetrating Probes to Explore the World around Us",slug:"cosmic-ray-muons-as-penetrating-probes-to-explore-the-world-around-us",totalDownloads:1400,totalCrossrefCites:3,totalDimensionsCites:5,abstract:"Secondary cosmic muons provide a powerful probe to explore various aspects of the world around us. Various physical processes have been employed over the last years for such applications. Muon absorption was used to probe the interior of natural and man-made structures, from the Egypt pyramids to big volcanoes, contributing to interdisciplinary studies. Multiple scattering was employed to reconstruct the location of scattering centres, producing 2D and 3D images of the interior of hidden volumes (muon tomography). Additional possibilities of cosmic muons have been exploited even for the alignment of large civil structures and in the study of their stability. All these applications benefit from the development of advanced detection techniques and improvement in software algorithms. This contribution surveys the state of the art of these applications, with special emphasis on their possibilities and limitations.",book:{id:"6768",slug:"cosmic-rays",title:"Cosmic Rays",fullTitle:"Cosmic Rays"},signatures:"Paola La Rocca, Domenico Lo Presti and Francesco Riggi",authors:[{id:"18197",title:"Dr.",name:"Francesco",middleName:null,surname:"Riggi",slug:"francesco-riggi",fullName:"Francesco Riggi"},{id:"18200",title:"Dr.",name:"Paola",middleName:null,surname:"La Rocca",slug:"paola-la-rocca",fullName:"Paola La Rocca"},{id:"243971",title:"Dr.",name:"Domenico",middleName:null,surname:"Lo Presti",slug:"domenico-lo-presti",fullName:"Domenico Lo Presti"}]}],onlineFirstChaptersFilter:{topicId:"221",limit:6,offset:0},onlineFirstChaptersCollection:[],onlineFirstChaptersTotal:0},preDownload:{success:null,errors:{}},subscriptionForm:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[],offset:8,limit:8,total:0},allSeries:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:11,numberOfPublishedChapters:91,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:108,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:33,numberOfPublishedChapters:333,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:14,numberOfPublishedChapters:145,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:11,numberOfPublishedChapters:144,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!0},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:126,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:11,numberOfPublishedChapters:113,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:23,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2753-894X",doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:13,numberOfOpenTopics:1,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!0},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:5,numberOfUpcomingTopics:0,issn:"2753-6580",doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],testimonialsList:[{id:"13",text:"The collaboration with and support of the technical staff of IntechOpen is fantastic. The whole process of submitting an article and editing of the submitted article goes extremely smooth and fast, the number of reads and downloads of chapters is high, and the contributions are also frequently cited.",author:{id:"55578",name:"Antonio",surname:"Jurado-Navas",institutionString:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRisIQAS/Profile_Picture_1626166543950",slug:"antonio-jurado-navas",institution:{id:"720",name:"University of Malaga",country:{id:null,name:"Spain"}}}},{id:"6",text:"It is great to work with the IntechOpen to produce a worthwhile collection of research that also becomes a great educational resource and guide for future research endeavors.",author:{id:"259298",name:"Edward",surname:"Narayan",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259298/images/system/259298.jpeg",slug:"edward-narayan",institution:{id:"3",name:"University of Queensland",country:{id:null,name:"Australia"}}}}]},series:{item:{id:"7",title:"Biomedical Engineering",doi:"10.5772/intechopen.71985",issn:"2631-5343",scope:"Biomedical Engineering is one of the fastest-growing interdisciplinary branches of science and industry. The combination of electronics and computer science with biology and medicine has improved patient diagnosis, reduced rehabilitation time, and helped to facilitate a better quality of life. Nowadays, all medical imaging devices, medical instruments, or new laboratory techniques result from the cooperation of specialists in various fields. The series of Biomedical Engineering books covers such areas of knowledge as chemistry, physics, electronics, medicine, and biology. 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Dr. Koprowski has authored more than a hundred research papers with dozens in impact factor (IF) journals and has authored or co-authored six books. Additionally, he is the author of several national and international patents in the field of biomedical devices and imaging. Since 2011, he has been a reviewer of grants and projects (including EU projects) in biomedical engineering.",institutionString:null,institution:{name:"University of Silesia",institutionURL:null,country:{name:"Poland"}}},editorTwo:null,editorThree:null},subseries:{paginationCount:4,paginationItems:[{id:"14",title:"Cell and Molecular Biology",coverUrl:"https://cdn.intechopen.com/series_topics/covers/14.jpg",isOpenForSubmission:!0,editor:{id:"165627",title:"Dr.",name:"Rosa María",middleName:null,surname:"Martínez-Espinosa",slug:"rosa-maria-martinez-espinosa",fullName:"Rosa María Martínez-Espinosa",profilePictureURL:"https://mts.intechopen.com/storage/users/165627/images/system/165627.jpeg",biography:"Rosa María Martínez-Espinosa is a Full Professor of Biochemistry and Molecular Biology at the University of Alicante, Spain, and has been the vice president of International Relations and Development Cooperation at this university since 2010. She created the research group in applied biochemistry in 2017 (https://web.ua.es/en/appbiochem/), and from 1999 to the present has made more than 200 contributions to Spanish and international conferences. Furthermore, she has around seventy-five scientific publications in indexed journals, eighty book chapters, and one patent to her credit. Her research work focuses on microbial metabolism (particularly on extremophile microorganisms), purification and characterization of enzymes with potential industrial and biotechnological applications, protocol optimization for genetically manipulating microorganisms, gene regulation characterization, carotenoid (pigment) production, and design and development of contaminated water and soil bioremediation processes by means of microorganisms. This research has received competitive public grants from the European Commission, the Spanish Ministry of Economy and Competitiveness, the Valencia Region Government, and the University of Alicante.",institutionString:"University of Alicante",institution:{name:"University of Alicante",institutionURL:null,country:{name:"Spain"}}},editorTwo:null,editorThree:null},{id:"15",title:"Chemical Biology",coverUrl:"https://cdn.intechopen.com/series_topics/covers/15.jpg",isOpenForSubmission:!0,editor:{id:"441442",title:"Dr.",name:"Şükrü",middleName:null,surname:"Beydemir",slug:"sukru-beydemir",fullName:"Şükrü Beydemir",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00003GsUoIQAV/Profile_Picture_1634557147521",biography:"Dr. Şükrü Beydemir obtained a BSc in Chemistry in 1995 from Yüzüncü Yıl University, MSc in Biochemistry in 1998, and PhD in Biochemistry in 2002 from Atatürk University, Turkey. He performed post-doctoral studies at Max-Planck Institute, Germany, and University of Florence, Italy in addition to making several scientific visits abroad. He currently works as a Full Professor of Biochemistry in the Faculty of Pharmacy, Anadolu University, Turkey. Dr. Beydemir has published over a hundred scientific papers spanning protein biochemistry, enzymology and medicinal chemistry, reviews, book chapters and presented several conferences to scientists worldwide. He has received numerous publication awards from various international scientific councils. He serves in the Editorial Board of several international journals. Dr. Beydemir is also Rector of Bilecik Şeyh Edebali University, Turkey.",institutionString:null,institution:{name:"Anadolu University",institutionURL:null,country:{name:"Turkey"}}},editorTwo:{id:"13652",title:"Prof.",name:"Deniz",middleName:null,surname:"Ekinci",slug:"deniz-ekinci",fullName:"Deniz Ekinci",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYLT1QAO/Profile_Picture_1634557223079",biography:"Dr. Deniz Ekinci obtained a BSc in Chemistry in 2004, MSc in Biochemistry in 2006, and PhD in Biochemistry in 2009 from Atatürk University, Turkey. He studied at Stetson University, USA, in 2007-2008 and at the Max Planck Institute of Molecular Cell Biology and Genetics, Germany, in 2009-2010. Dr. Ekinci currently works as a Full Professor of Biochemistry in the Faculty of Agriculture and is the Head of the Enzyme and Microbial Biotechnology Division, Ondokuz Mayıs University, Turkey. He is a member of the Turkish Biochemical Society, American Chemical Society, and German Genetics society. Dr. Ekinci published around ninety scientific papers, reviews and book chapters, and presented several conferences to scientists. He has received numerous publication awards from several scientific councils. Dr. Ekinci serves as the Editor in Chief of four international books and is involved in the Editorial Board of several international journals.",institutionString:null,institution:{name:"Ondokuz Mayıs University",institutionURL:null,country:{name:"Turkey"}}},editorThree:null},{id:"17",title:"Metabolism",coverUrl:"https://cdn.intechopen.com/series_topics/covers/17.jpg",isOpenForSubmission:!0,editor:{id:"138626",title:"Dr.",name:"Yannis",middleName:null,surname:"Karamanos",slug:"yannis-karamanos",fullName:"Yannis Karamanos",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002g6Jv2QAE/Profile_Picture_1629356660984",biography:"Yannis Karamanos, born in Greece in 1953, completed his pre-graduate studies at the Université Pierre et Marie Curie, Paris, then his Masters and Doctoral degree at the Université de Lille (1983). He was associate professor at the University of Limoges (1987) before becoming full professor of biochemistry at the Université d’Artois (1996). He worked on the structure-function relationships of glycoconjugates and his main project was the investigations on the biological roles of the de-N-glycosylation enzymes (Endo-N-acetyl-β-D-glucosaminidase and peptide-N4-(N-acetyl-β-glucosaminyl) asparagine amidase). From 2002 he contributes to the understanding of the Blood-brain barrier functioning using proteomics approaches. He has published more than 70 papers. His teaching areas are energy metabolism and regulation, integration and organ specialization and metabolic adaptation.",institutionString:null,institution:{name:"Artois University",institutionURL:null,country:{name:"France"}}},editorTwo:null,editorThree:null},{id:"18",title:"Proteomics",coverUrl:"https://cdn.intechopen.com/series_topics/covers/18.jpg",isOpenForSubmission:!0,editor:{id:"200689",title:"Prof.",name:"Paolo",middleName:null,surname:"Iadarola",slug:"paolo-iadarola",fullName:"Paolo Iadarola",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSCl8QAG/Profile_Picture_1623568118342",biography:"Paolo Iadarola graduated with a degree in Chemistry from the University of Pavia (Italy) in July 1972. He then worked as an Assistant Professor at the Faculty of Science of the same University until 1984. In 1985, Prof. Iadarola became Associate Professor at the Department of Biology and Biotechnologies of the University of Pavia and retired in October 2017. Since then, he has been working as an Adjunct Professor in the same Department at the University of Pavia. His research activity during the first years was primarily focused on the purification and structural characterization of enzymes from animal and plant sources. During this period, Prof. Iadarola familiarized himself with the conventional techniques used in column chromatography, spectrophotometry, manual Edman degradation, and electrophoresis). Since 1995, he has been working on: i) the determination in biological fluids (serum, urine, bronchoalveolar lavage, sputum) of proteolytic activities involved in the degradation processes of connective tissue matrix, and ii) on the identification of biological markers of lung diseases. In this context, he has developed and validated new methodologies (e.g., Capillary Electrophoresis coupled to Laser-Induced Fluorescence, CE-LIF) whose application enabled him to determine both the amounts of biochemical markers (Desmosines) in urine/serum of patients affected by Chronic Obstructive Pulmonary Disease (COPD) and the activity of proteolytic enzymes (Human Neutrophil Elastase, Cathepsin G, Pseudomonas aeruginosa elastase) in sputa of these patients. More recently, Prof. Iadarola was involved in developing techniques such as two-dimensional electrophoresis coupled to liquid chromatography/mass spectrometry (2DE-LC/MS) for the proteomic analysis of biological fluids aimed at the identification of potential biomarkers of different lung diseases. He is the author of about 150 publications (According to Scopus: H-Index: 23; Total citations: 1568- According to WOS: H-Index: 20; Total Citations: 1296) of peer-reviewed international journals. He is a Consultant Reviewer for several journals, including the Journal of Chromatography A, Journal of Chromatography B, Plos ONE, Proteomes, International Journal of Molecular Science, Biotech, Electrophoresis, and others. He is also Associate Editor of Biotech.",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorTwo:{id:"201414",title:"Dr.",name:"Simona",middleName:null,surname:"Viglio",slug:"simona-viglio",fullName:"Simona Viglio",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRKDHQA4/Profile_Picture_1630402531487",biography:"Simona Viglio is an Associate Professor of Biochemistry at the Department of Molecular Medicine at the University of Pavia. She has been working since 1995 on the determination of proteolytic enzymes involved in the degradation process of connective tissue matrix and on the identification of biological markers of lung diseases. She gained considerable experience in developing and validating new methodologies whose applications allowed her to determine both the amount of biomarkers (Desmosine and Isodesmosine) in the urine of patients affected by COPD, and the activity of proteolytic enzymes (HNE, Cathepsin G, Pseudomonas aeruginosa elastase) in the sputa of these patients. Simona Viglio was also involved in research dealing with the supplementation of amino acids in patients with brain injury and chronic heart failure. She is presently engaged in the development of 2-DE and LC-MS techniques for the study of proteomics in biological fluids. The aim of this research is the identification of potential biomarkers of lung diseases. 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Radiotherapy and Nuclear Medicine Technology has always been my aspiration and my life. As years passed I accumulated a tremendous amount of skills and knowledge in Radiotherapy and Nuclear Medicine, Conventional Radiology, Radiation Protection, Bioinformatics Technology, PACS, Image processing, clinically and lecturing that will enable me to provide a valuable service to the community as a Researcher and Consultant in this field. My method of translating this into day to day in clinical practice is non-exhaustible and my habit of exchanging knowledge and expertise with others in those fields is the code and secret of success.",institutionString:null,institution:{name:"Majmaah University",country:{name:"Saudi Arabia"}}},{id:"313277",title:"Dr.",name:"Bartłomiej",middleName:null,surname:"Płaczek",slug:"bartlomiej-placzek",fullName:"Bartłomiej Płaczek",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/313277/images/system/313277.jpg",biography:"Bartłomiej Płaczek, MSc (2002), Ph.D. (2005), Habilitation (2016), is a professor at the University of Silesia, Institute of Computer Science, Poland, and an expert from the National Centre for Research and Development. His research interests include sensor networks, smart sensors, intelligent systems, and image processing with applications in healthcare and medicine. He is the author or co-author of more than seventy papers in peer-reviewed journals and conferences as well as the co-author of several books. He serves as a reviewer for many scientific journals, international conferences, and research foundations. Since 2010, Dr. Placzek has been a reviewer of grants and projects (including EU projects) in the field of information technologies.",institutionString:"University of Silesia",institution:{name:"University of Silesia",country:{name:"Poland"}}},{id:"35000",title:"Prof.",name:"Ulrich H.P",middleName:"H.P.",surname:"Fischer",slug:"ulrich-h.p-fischer",fullName:"Ulrich H.P Fischer",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/35000/images/3052_n.jpg",biography:"Academic and Professional Background\nUlrich H. P. has Diploma and PhD degrees in Physics from the Free University Berlin, Germany. He has been working on research positions in the Heinrich-Hertz-Institute in Germany. Several international research projects has been performed with European partners from France, Netherlands, Norway and the UK. He is currently Professor of Communications Systems at the Harz University of Applied Sciences, Germany.\n\nPublications and Publishing\nHe has edited one book, a special interest book about ‘Optoelectronic Packaging’ (VDE, Berlin, Germany), and has published over 100 papers and is owner of several international patents for WDM over POF key elements.\n\nKey Research and Consulting Interests\nUlrich’s research activity has always been related to Spectroscopy and Optical Communications Technology. Specific current interests include the validation of complex instruments, and the application of VR technology to the development and testing of measurement systems. He has been reviewer for several publications of the Optical Society of America\\'s including Photonics Technology Letters and Applied Optics.\n\nPersonal Interests\nThese include motor cycling in a very relaxed manner and performing martial arts.",institutionString:null,institution:{name:"Charité",country:{name:"Germany"}}},{id:"341622",title:"Ph.D.",name:"Eduardo",middleName:null,surname:"Rojas Alvarez",slug:"eduardo-rojas-alvarez",fullName:"Eduardo Rojas Alvarez",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/341622/images/15892_n.jpg",biography:null,institutionString:null,institution:{name:"University of Cuenca",country:{name:"Ecuador"}}},{id:"215610",title:"Prof.",name:"Muhammad",middleName:null,surname:"Sarfraz",slug:"muhammad-sarfraz",fullName:"Muhammad Sarfraz",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/215610/images/system/215610.jpeg",biography:"Muhammad Sarfraz is a professor in the Department of Information Science, Kuwait University. His research interests include computer graphics, computer vision, image processing, machine learning, pattern recognition, soft computing, data science, intelligent systems, information technology, and information systems. Prof. Sarfraz has been a keynote/invited speaker on various platforms around the globe. He has advised various students for their MSc and Ph.D. theses. He has published more than 400 publications as books, journal articles, and conference papers. He is a member of various professional societies and a chair and member of the International Advisory Committees and Organizing Committees of various international conferences. Prof. Sarfraz is also an editor-in-chief and editor of various international journals.",institutionString:"Kuwait University",institution:{name:"Kuwait University",country:{name:"Kuwait"}}},{id:"32650",title:"Prof.",name:"Lukas",middleName:"Willem",surname:"Snyman",slug:"lukas-snyman",fullName:"Lukas Snyman",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/32650/images/4136_n.jpg",biography:"Lukas Willem Snyman received his basic education at primary and high schools in South Africa, Eastern Cape. He enrolled at today's Nelson Metropolitan University and graduated from this university with a BSc in Physics and Mathematics, B.Sc Honors in Physics, MSc in Semiconductor Physics, and a Ph.D. in Semiconductor Physics in 1987. After his studies, he chose an academic career and devoted his energy to the teaching of physics to first, second, and third-year students. After positions as a lecturer at the University of Port Elizabeth, he accepted a position as Associate Professor at the University of Pretoria, South Africa.\r\n\r\nIn 1992, he motivates the concept of 'television and computer-based education” as means to reach large student numbers with only the best of teaching expertise and publishes an article on the concept in the SA Journal of Higher Education of 1993 (and later in 2003). The University of Pretoria subsequently approved a series of test projects on the concept with outreach to Mamelodi and Eerste Rust in 1993. In 1994, the University established a 'Unit for Telematic Education ' as a support section for multiple faculties at the University of Pretoria. In subsequent years, the concept of 'telematic education” subsequently becomes well established in academic circles in South Africa, grew in popularity, and is adopted by many universities and colleges throughout South Africa as a medium of enhancing education and training, as a method to reaching out to far out communities, and as a means to enhance study from the home environment.\r\n\r\nProfessor Snyman in subsequent years pursued research in semiconductor physics, semiconductor devices, microelectronics, and optoelectronics.\r\n\r\nIn 2000 he joined the TUT as a full professor. Here served for a period as head of the Department of Electronic Engineering. Here he makes contributions to solar energy development, microwave and optoelectronic device development, silicon photonics, as well as contributions to new mobile telecommunication systems and network planning in SA.\r\n\r\nCurrently, he teaches electronics and telecommunications at the TUT to audiences ranging from first-year students to Ph.D. level.\r\n\r\nFor his research in the field of 'Silicon Photonics” since 1990, he has published (as author and co-author) about thirty internationally reviewed articles in scientific journals, contributed to more than forty international conferences, about 25 South African provisional patents (as inventor and co-inventor), 8 PCT international patent applications until now. Of these, two USA patents applications, two European Patents, two Korean patents, and ten SA patents have been granted. A further 4 USA patents, 5 European patents, 3 Korean patents, 3 Chinese patents, and 3 Japanese patents are currently under consideration.\r\n\r\nRecently he has also published an extensive scholarly chapter in an internet open access book on 'Integrating Microphotonic Systems and MOEMS into standard Silicon CMOS Integrated circuitry”.\r\n\r\nFurthermore, Professor Snyman recently steered a new initiative at the TUT by introducing a 'Laboratory for Innovative Electronic Systems ' at the Department of Electrical Engineering. The model of this laboratory or center is to primarily combine outputs as achieved by high-level research with lower-level system development and entrepreneurship in a technical university environment. Students are allocated to projects at different levels with PhDs and Master students allocated to the generation of new knowledge and new technologies, while students at the diploma and Baccalaureus level are allocated to electronic systems development with a direct and a near application for application in industry or the commercial and public sectors in South Africa.\r\n\r\nProfessor Snyman received the WIRSAM Award of 1983 and the WIRSAM Award in 1985 in South Africa for best research papers by a young scientist at two international conferences on electron microscopy in South Africa. He subsequently received the SA Microelectronics Award for the best dissertation emanating from studies executed at a South African university in the field of Physics and Microelectronics in South Africa in 1987. In October of 2011, Professor Snyman received the prestigious Institutional Award for 'Innovator of the Year” for 2010 at the Tshwane University of Technology, South Africa. This award was based on the number of patents recognized and granted by local and international institutions as well as for his contributions concerning innovation at the TUT.",institutionString:null,institution:{name:"University of South Africa",country:{name:"South Africa"}}},{id:"317279",title:"Mr.",name:"Ali",middleName:"Usama",surname:"Syed",slug:"ali-syed",fullName:"Ali Syed",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/317279/images/16024_n.png",biography:"A creative, talented, and innovative young professional who is dedicated, well organized, and capable research fellow with two years of experience in graduate-level research, published in engineering journals and book, with related expertise in Bio-robotics, equally passionate about the aesthetics of the mechanical and electronic system, obtained expertise in the use of MS Office, MATLAB, SolidWorks, LabVIEW, Proteus, Fusion 360, having a grasp on python, C++ and assembly language, possess proven ability in acquiring research grants, previous appointments with social and educational societies with experience in administration, current affiliations with IEEE and Web of Science, a confident presenter at conferences and teacher in classrooms, able to explain complex information to audiences of all levels.",institutionString:null,institution:{name:"Air University",country:{name:"Pakistan"}}},{id:"75526",title:"Ph.D.",name:"Zihni Onur",middleName:null,surname:"Uygun",slug:"zihni-onur-uygun",fullName:"Zihni Onur Uygun",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/75526/images/12_n.jpg",biography:"My undergraduate education and my Master of Science educations at Ege University and at Çanakkale Onsekiz Mart University have given me a firm foundation in Biochemistry, Analytical Chemistry, Biosensors, Bioelectronics, Physical Chemistry and Medicine. After obtaining my degree as a MSc in analytical chemistry, I started working as a research assistant in Ege University Medical Faculty in 2014. In parallel, I enrolled to the MSc program at the Department of Medical Biochemistry at Ege University to gain deeper knowledge on medical and biochemical sciences as well as clinical chemistry in 2014. In my PhD I deeply researched on biosensors and bioelectronics and finished in 2020. Now I have eleven SCI-Expanded Index published papers, 6 international book chapters, referee assignments for different SCIE journals, one international patent pending, several international awards, projects and bursaries. In parallel to my research assistant position at Ege University Medical Faculty, Department of Medical Biochemistry, in April 2016, I also founded a Start-Up Company (Denosens Biotechnology LTD) by the support of The Scientific and Technological Research Council of Turkey. Currently, I am also working as a CEO in Denosens Biotechnology. The main purposes of the company, which carries out R&D as a research center, are to develop new generation biosensors and sensors for both point-of-care diagnostics; such as glucose, lactate, cholesterol and cancer biomarker detections. My specific experimental and instrumental skills are Biochemistry, Biosensor, Analytical Chemistry, Electrochemistry, Mobile phone based point-of-care diagnostic device, POCTs and Patient interface designs, HPLC, Tandem Mass Spectrometry, Spectrophotometry, ELISA.",institutionString:null,institution:{name:"Ege University",country:{name:"Turkey"}}},{id:"267434",title:"Dr.",name:"Rohit",middleName:null,surname:"Raja",slug:"rohit-raja",fullName:"Rohit Raja",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/267434/images/system/267434.jpg",biography:"Dr. Rohit Raja received Ph.D. in Computer Science and Engineering from Dr. CVRAMAN University in 2016. His main research interest includes Face recognition and Identification, Digital Image Processing, Signal Processing, and Networking. Presently he is working as Associate Professor in IT Department, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur (CG), India. He has authored several Journal and Conference Papers. He has good Academics & Research experience in various areas of CSE and IT. He has filed and successfully published 27 Patents. He has received many time invitations to be a Guest at IEEE Conferences. He has published 100 research papers in various International/National Journals (including IEEE, Springer, etc.) and Proceedings of the reputed International/ National Conferences (including Springer and IEEE). He has been nominated to the board of editors/reviewers of many peer-reviewed and refereed Journals (including IEEE, Springer).",institutionString:"Guru Ghasidas Vishwavidyalaya",institution:{name:"Guru Ghasidas Vishwavidyalaya",country:{name:"India"}}},{id:"246502",title:"Dr.",name:"Jaya T.",middleName:"T",surname:"Varkey",slug:"jaya-t.-varkey",fullName:"Jaya T. Varkey",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/246502/images/11160_n.jpg",biography:"Jaya T. Varkey, PhD, graduated with a degree in Chemistry from Cochin University of Science and Technology, Kerala, India. She obtained a PhD in Chemistry from the School of Chemical Sciences, Mahatma Gandhi University, Kerala, India, and completed a post-doctoral fellowship at the University of Minnesota, USA. She is a research guide at Mahatma Gandhi University and Associate Professor in Chemistry, St. Teresa’s College, Kochi, Kerala, India.\nDr. Varkey received a National Young Scientist award from the Indian Science Congress (1995), a UGC Research award (2016–2018), an Indian National Science Academy (INSA) Visiting Scientist award (2018–2019), and a Best Innovative Faculty award from the All India Association for Christian Higher Education (AIACHE) (2019). She Hashas received the Sr. Mary Cecil prize for best research paper three times. She was also awarded a start-up to develop a tea bag water filter. \nDr. Varkey has published two international books and twenty-seven international journal publications. She is an editorial board member for five international journals.",institutionString:"St. Teresa’s College",institution:null},{id:"250668",title:"Dr.",name:"Ali",middleName:null,surname:"Nabipour Chakoli",slug:"ali-nabipour-chakoli",fullName:"Ali Nabipour Chakoli",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/250668/images/system/250668.jpg",biography:"Academic Qualification:\r\n•\tPhD in Materials Physics and Chemistry, From: Sep. 2006, to: Sep. 2010, School of Materials Science and Engineering, Harbin Institute of Technology, Thesis: Structure and Shape Memory Effect of Functionalized MWCNTs/poly (L-lactide-co-ε-caprolactone) Nanocomposites. Supervisor: Prof. Wei Cai,\r\n•\tM.Sc in Applied Physics, From: 1996, to: 1998, Faculty of Physics & Nuclear Science, Amirkabir Uni. of Technology, Tehran, Iran, Thesis: Determination of Boron in Micro alloy Steels with solid state nuclear track detectors by neutron induced auto radiography, Supervisors: Dr. M. Hosseini Ashrafi and Dr. A. Hosseini.\r\n•\tB.Sc. in Applied Physics, From: 1991, to: 1996, Faculty of Physics & Nuclear Science, Amirkabir Uni. of Technology, Tehran, Iran, Thesis: Design of shielding for Am-Be neutron sources for In Vivo neutron activation analysis, Supervisor: Dr. M. Hosseini Ashrafi.\r\n\r\nResearch Experiences:\r\n1.\tNanomaterials, Carbon Nanotubes, Graphene: Synthesis, Functionalization and Characterization,\r\n2.\tMWCNTs/Polymer Composites: Fabrication and Characterization, \r\n3.\tShape Memory Polymers, Biodegradable Polymers, ORC, Collagen,\r\n4.\tMaterials Analysis and Characterizations: TEM, SEM, XPS, FT-IR, Raman, DSC, DMA, TGA, XRD, GPC, Fluoroscopy, \r\n5.\tInteraction of Radiation with Mater, Nuclear Safety and Security, NDT(RT),\r\n6.\tRadiation Detectors, Calibration (SSDL),\r\n7.\tCompleted IAEA e-learning Courses:\r\nNuclear Security (15 Modules),\r\nNuclear Safety:\r\nTSA 2: Regulatory Protection in Occupational Exposure,\r\nTips & Tricks: Radiation Protection in Radiography,\r\nSafety and Quality in Radiotherapy,\r\nCourse on Sealed Radioactive Sources,\r\nCourse on Fundamentals of Environmental Remediation,\r\nCourse on Planning for Environmental Remediation,\r\nKnowledge Management Orientation Course,\r\nFood Irradiation - Technology, Applications and Good Practices,\r\nEmployment:\r\nFrom 2010 to now: Academic staff, Nuclear Science and Technology Research Institute, Kargar Shomali, Tehran, Iran, P.O. Box: 14395-836.\r\nFrom 1997 to 2006: Expert of Materials Analysis and Characterization. Research Center of Agriculture and Medicine. Rajaeeshahr, Karaj, Iran, P. O. Box: 31585-498.",institutionString:"Atomic Energy Organization of Iran",institution:{name:"Atomic Energy Organization of Iran",country:{name:"Iran"}}},{id:"248279",title:"Dr.",name:"Monika",middleName:"Elzbieta",surname:"Machoy",slug:"monika-machoy",fullName:"Monika Machoy",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/248279/images/system/248279.jpeg",biography:"Monika Elżbieta Machoy, MD, graduated with distinction from the Faculty of Medicine and Dentistry at the Pomeranian Medical University in 2009, defended her PhD thesis with summa cum laude in 2016 and is currently employed as a researcher at the Department of Orthodontics of the Pomeranian Medical University. She expanded her professional knowledge during a one-year scholarship program at the Ernst Moritz Arndt University in Greifswald, Germany and during a three-year internship at the Technical University in Dresden, Germany. She has been a speaker at numerous orthodontic conferences, among others, American Association of Orthodontics, European Orthodontic Symposium and numerous conferences of the Polish Orthodontic Society. She conducts research focusing on the effect of orthodontic treatment on dental and periodontal tissues and the causes of pain in orthodontic patients.",institutionString:"Pomeranian Medical University",institution:{name:"Pomeranian Medical University",country:{name:"Poland"}}},{id:"252743",title:"Prof.",name:"Aswini",middleName:"Kumar",surname:"Kar",slug:"aswini-kar",fullName:"Aswini Kar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/252743/images/10381_n.jpg",biography:"uploaded in cv",institutionString:null,institution:{name:"KIIT University",country:{name:"India"}}},{id:"204256",title:"Dr.",name:"Anil",middleName:"Kumar",surname:"Kumar Sahu",slug:"anil-kumar-sahu",fullName:"Anil Kumar Sahu",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/204256/images/14201_n.jpg",biography:"I have nearly 11 years of research and teaching experience. I have done my master degree from University Institute of Pharmacy, Pt. Ravi Shankar Shukla University, Raipur, Chhattisgarh India. I have published 16 review and research articles in international and national journals and published 4 chapters in IntechOpen, the world’s leading publisher of Open access books. I have presented many papers at national and international conferences. I have received research award from Indian Drug Manufacturers Association in year 2015. My research interest extends from novel lymphatic drug delivery systems, oral delivery system for herbal bioactive to formulation optimization.",institutionString:null,institution:{name:"Chhattisgarh Swami Vivekanand Technical University",country:{name:"India"}}},{id:"253468",title:"Dr.",name:"Mariusz",middleName:null,surname:"Marzec",slug:"mariusz-marzec",fullName:"Mariusz Marzec",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/253468/images/system/253468.png",biography:"An assistant professor at Department of Biomedical Computer Systems, at Institute of Computer Science, Silesian University in Katowice. Scientific interests: computer analysis and processing of images, biomedical images, databases and programming languages. He is an author and co-author of scientific publications covering analysis and processing of biomedical images and development of database systems.",institutionString:"University of Silesia",institution:{name:"University of Silesia",country:{name:"Poland"}}},{id:"212432",title:"Prof.",name:"Hadi",middleName:null,surname:"Mohammadi",slug:"hadi-mohammadi",fullName:"Hadi Mohammadi",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/212432/images/system/212432.jpeg",biography:"Dr. Hadi Mohammadi is a biomedical engineer with hands-on experience in the design and development of many engineering structures and medical devices through various projects that he has been involved in over the past twenty years. Dr. Mohammadi received his BSc. and MSc. degrees in Mechanical Engineering from Sharif University of Technology, Tehran, Iran, and his PhD. degree in Biomedical Engineering (biomaterials) from the University of Western Ontario. He was a postdoctoral trainee for almost four years at University of Calgary and Harvard Medical School. He is an industry innovator having created the technology to produce lifelike synthetic platforms that can be used for the simulation of almost all cardiovascular reconstructive surgeries. He’s been heavily involved in the design and development of cardiovascular devices and technology for the past 10 years. He is currently an Assistant Professor with the University of British Colombia, Canada.",institutionString:"University of British Columbia",institution:{name:"University of British Columbia",country:{name:"Canada"}}},{id:"254463",title:"Prof.",name:"Haisheng",middleName:null,surname:"Yang",slug:"haisheng-yang",fullName:"Haisheng Yang",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/254463/images/system/254463.jpeg",biography:"Haisheng Yang, Ph.D., Professor and Director of the Department of Biomedical Engineering, College of Life Science and Bioengineering, Beijing University of Technology. He received his Ph.D. degree in Mechanics/Biomechanics from Harbin Institute of Technology (jointly with University of California, Berkeley). Afterwards, he worked as a Postdoctoral Research Associate in the Purdue Musculoskeletal Biology and Mechanics Lab at the Department of Basic Medical Sciences, Purdue University, USA. He also conducted research in the Research Centre of Shriners Hospitals for Children-Canada at McGill University, Canada. Dr. Yang has over 10 years research experience in orthopaedic biomechanics and mechanobiology of bone adaptation and regeneration. He earned an award from Beijing Overseas Talents Aggregation program in 2017 and serves as Beijing Distinguished Professor.",institutionString:null,institution:{name:"Beijing University of Technology",country:{name:"China"}}},{id:"89721",title:"Dr.",name:"Mehmet",middleName:"Cuneyt",surname:"Ozmen",slug:"mehmet-ozmen",fullName:"Mehmet Ozmen",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/89721/images/7289_n.jpg",biography:null,institutionString:null,institution:{name:"Gazi University",country:{name:"Turkey"}}},{id:"265335",title:"Mr.",name:"Stefan",middleName:"Radnev",surname:"Stefanov",slug:"stefan-stefanov",fullName:"Stefan Stefanov",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/265335/images/7562_n.jpg",biography:null,institutionString:null,institution:{name:"Medical University Plovdiv",country:{name:"Bulgaria"}}},{id:"242893",title:"Ph.D. Student",name:"Joaquim",middleName:null,surname:"De Moura",slug:"joaquim-de-moura",fullName:"Joaquim De Moura",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/242893/images/7133_n.jpg",biography:"Joaquim de Moura received his degree in Computer Engineering in 2014 from the University of A Coruña (Spain). In 2016, he received his M.Sc degree in Computer Engineering from the same university. He is currently pursuing his Ph.D degree in Computer Science in a collaborative project between ophthalmology centers in Galicia and the University of A Coruña. His research interests include computer vision, machine learning algorithms and analysis and medical imaging processing of various kinds.",institutionString:null,institution:{name:"University of A Coruña",country:{name:"Spain"}}},{id:"294334",title:"B.Sc.",name:"Marc",middleName:null,surname:"Bruggeman",slug:"marc-bruggeman",fullName:"Marc Bruggeman",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/294334/images/8242_n.jpg",biography:"Chemical engineer graduate, with a passion for material science and specific interest in polymers - their near infinite applications intrigue me. \n\nI plan to continue my scientific career in the field of polymeric biomaterials as I am fascinated by intelligent, bioactive and biomimetic materials for use in both consumer and medical applications.",institutionString:null,institution:null},{id:"255757",title:"Dr.",name:"Igor",middleName:"Victorovich",surname:"Lakhno",slug:"igor-lakhno",fullName:"Igor Lakhno",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/255757/images/system/255757.jpg",biography:"Igor Victorovich Lakhno was born in 1971 in Kharkiv (Ukraine). \nMD – 1994, Kharkiv National Medical Univesity.\nOb&Gyn; – 1997, master courses in Kharkiv Medical Academy of Postgraduate Education.\nPh.D. – 1999, Kharkiv National Medical Univesity.\nDSC – 2019, PL Shupik National Academy of Postgraduate Education \nProfessor – 2021, Department of Obstetrics and Gynecology of VN Karazin Kharkiv National University\nHead of Department – 2021, Department of Perinatology, Obstetrics and gynecology of Kharkiv Medical Academy of Postgraduate Education\nIgor Lakhno has been graduated from international training courses on reproductive medicine and family planning held at Debrecen University (Hungary) in 1997. Since 1998 Lakhno Igor has worked as an associate professor in the department of obstetrics and gynecology of VN Karazin National University and an associate professor of the perinatology, obstetrics, and gynecology department of Kharkiv Medical Academy of Postgraduate Education. Since June 2019 he’s been a professor in the department of obstetrics and gynecology of VN Karazin National University and a professor of the perinatology, obstetrics, and gynecology department. He’s affiliated with Kharkiv Medical Academy of Postgraduate Education as a Head of Department from November 2021. Igor Lakhno has participated in several international projects on fetal non-invasive electrocardiography (with Dr. J. A. Behar (Technion), Prof. D. Hoyer (Jena University), and José Alejandro Díaz Méndez (National Institute of Astrophysics, Optics, and Electronics, Mexico). He’s an author of about 200 printed works and there are 31 of them in Scopus or Web of Science databases. Igor Lakhno is a member of the Editorial Board of Reproductive Health of Woman, Emergency Medicine, and Technology Transfer Innovative Solutions in Medicine (Estonia). He is a medical Editor of “Z turbotoyu pro zhinku”. Igor Lakhno is a reviewer of the Journal of Obstetrics and Gynaecology (Taylor and Francis), British Journal of Obstetrics and Gynecology (Wiley), Informatics in Medicine Unlocked (Elsevier), The Journal of Obstetrics and Gynecology Research (Wiley), Endocrine, Metabolic & Immune Disorders-Drug Targets (Bentham Open), The Open Biomedical Engineering Journal (Bentham Open), etc. He’s defended a dissertation for a DSc degree “Pre-eclampsia: prediction, prevention, and treatment”. Three years ago Igor Lakhno has participated in a training course on innovative technologies in medical education at Lublin Medical University (Poland). Lakhno Igor has participated as a speaker in several international conferences and congresses (International Conference on Biological Oscillations April 10th-14th 2016, Lancaster, UK, The 9th conference of the European Study Group on Cardiovascular Oscillations). His main scientific interests: are obstetrics, women’s health, fetal medicine, and cardiovascular medicine. \nIgor Lakhno is a consultant at Kharkiv municipal perinatal center. He’s graduated from training courses on endoscopy in gynecology. He has 28 years of practical experience in the field.",institutionString:null,institution:null},{id:"244950",title:"Dr.",name:"Salvatore",middleName:null,surname:"Di Lauro",slug:"salvatore-di-lauro",fullName:"Salvatore Di Lauro",position:null,profilePictureURL:"https://intech-files.s3.amazonaws.com/0030O00002bSF1HQAW/ProfilePicture%202021-12-20%2014%3A54%3A14.482",biography:"Name:\n\tSALVATORE DI LAURO\nAddress:\n\tHospital Clínico Universitario Valladolid\nAvda Ramón y Cajal 3\n47005, Valladolid\nSpain\nPhone number: \nFax\nE-mail:\n\t+34 983420000 ext 292\n+34 983420084\nsadilauro@live.it\nDate and place of Birth:\nID Number\nMedical Licence \nLanguages\t09-05-1985. Villaricca (Italy)\n\nY1281863H\n474707061\nItalian (native language)\nSpanish (read, written, spoken)\nEnglish (read, written, spoken)\nPortuguese (read, spoken)\nFrench (read)\n\t\t\nCurrent position (title and company)\tDate (Year)\nVitreo-Retinal consultant in ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl. National Health System.\nVitreo-Retinal consultant in ophthalmology. Instituto Oftalmologico Recoletas. Red Hospitalaria Recoletas. Private practise.\t2017-today\n\n2019-today\n\t\n\t\nEducation (High school, university and postgraduate training > 3 months)\tDate (Year)\nDegree in Medicine and Surgery. University of Neaples 'Federico II”\nResident in Opthalmology. Hospital Clinico Universitario Valladolid\nMaster in Vitreo-Retina. IOBA. University of Valladolid\nFellow of the European Board of Ophthalmology. Paris\nMaster in Research in Ophthalmology. University of Valladolid\t2003-2009\n2012-2016\n2016-2017\n2016\n2012-2013\n\t\nEmployments (company and positions)\tDate (Year)\nResident in Ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl.\nFellow in Vitreo-Retina. IOBA. University of Valladolid\nVitreo-Retinal consultant in ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl. National Health System.\nVitreo-Retinal consultant in ophthalmology. Instituto Oftalmologico Recoletas. Red Hospitalaria Recoletas. \n\t2012-2016\n2016-2017\n2017-today\n\n2019-Today\n\n\n\t\nClinical Research Experience (tasks and role)\tDate (Year)\nAssociated investigator\n\n' FIS PI20/00740: DESARROLLO DE UNA CALCULADORA DE RIESGO DE\nAPARICION DE RETINOPATIA DIABETICA BASADA EN TECNICAS DE IMAGEN MULTIMODAL EN PACIENTES DIABETICOS TIPO 1. Grant by: Ministerio de Ciencia e Innovacion \n\n' (BIO/VA23/14) Estudio clínico multicéntrico y prospectivo para validar dos\nbiomarcadores ubicados en los genes p53 y MDM2 en la predicción de los resultados funcionales de la cirugía del desprendimiento de retina regmatógeno. Grant by: Gerencia Regional de Salud de la Junta de Castilla y León.\n' Estudio multicéntrico, aleatorizado, con enmascaramiento doble, en 2 grupos\nparalelos y de 52 semanas de duración para comparar la eficacia, seguridad e inmunogenicidad de SOK583A1 respecto a Eylea® en pacientes con degeneración macular neovascular asociada a la edad' (CSOK583A12301; N.EUDRA: 2019-004838-41; FASE III). Grant by Hexal AG\n\n' Estudio de fase III, aleatorizado, doble ciego, con grupos paralelos, multicéntrico para comparar la eficacia y la seguridad de QL1205 frente a Lucentis® en pacientes con degeneración macular neovascular asociada a la edad. (EUDRACT: 2018-004486-13). Grant by Qilu Pharmaceutical Co\n\n' Estudio NEUTON: Ensayo clinico en fase IV para evaluar la eficacia de aflibercept en pacientes Naive con Edema MacUlar secundario a Oclusion de Vena CenTral de la Retina (OVCR) en regimen de tratamientO iNdividualizado Treat and Extend (TAE)”, (2014-000975-21). Grant by Fundacion Retinaplus\n\n' Evaluación de la seguridad y bioactividad de anillos de tensión capsular en conejo. Proyecto Procusens. Grant by AJL, S.A.\n\n'Estudio epidemiológico, prospectivo, multicéntrico y abierto\\npara valorar la frecuencia de la conjuntivitis adenovírica diagnosticada mediante el test AdenoPlus®\\nTest en pacientes enfermos de conjuntivitis aguda”\\n. National, multicenter study. Grant by: NICOX.\n\nEuropean multicentric trial: 'Evaluation of clinical outcomes following the use of Systane Hydration in patients with dry eye”. Study Phase 4. Grant by: Alcon Labs'\n\nVLPs Injection and Activation in a Rabbit Model of Uveal Melanoma. Grant by Aura Bioscience\n\nUpdating and characterization of a rabbit model of uveal melanoma. Grant by Aura Bioscience\n\nEnsayo clínico en fase IV para evaluar las variantes genéticas de la vía del VEGF como biomarcadores de eficacia del tratamiento con aflibercept en pacientes con degeneración macular asociada a la edad (DMAE) neovascular. Estudio BIOIMAGE. IMO-AFLI-2013-01\n\nEstudio In-Eye:Ensayo clínico en fase IV, abierto, aleatorizado, de 2 brazos,\nmulticçentrico y de 12 meses de duración, para evaluar la eficacia y seguridad de un régimen de PRN flexible individualizado de 'esperar y extender' versus un régimen PRN según criterios de estabilización mediante evaluaciones mensuales de inyecciones intravítreas de ranibizumab 0,5 mg en pacientes naive con neovascularización coriodea secunaria a la degeneración macular relacionada con la edad. CP: CRFB002AES03T\n\nTREND: Estudio Fase IIIb multicéntrico, randomizado, de 12 meses de\nseguimiento con evaluador de la agudeza visual enmascarado, para evaluar la eficacia y la seguridad de ranibizumab 0.5mg en un régimen de tratar y extender comparado con un régimen mensual, en pacientes con degeneración macular neovascular asociada a la edad. CP: CRFB002A2411 Código Eudra CT:\n2013-002626-23\n\n\n\nPublications\t\n\n2021\n\n\n\n\n2015\n\n\n\n\n2021\n\n\n\n\n\n2021\n\n\n\n\n2015\n\n\n\n\n2015\n\n\n2014\n\n\n\n\n2015-16\n\n\n\n2015\n\n\n2014\n\n\n2014\n\n\n\n\n2014\n\n\n\n\n\n\n\n2014\n\nJose Carlos Pastor; Jimena Rojas; Salvador Pastor-Idoate; Salvatore Di Lauro; Lucia Gonzalez-Buendia; Santiago Delgado-Tirado. Proliferative vitreoretinopathy: A new concept of disease pathogenesis and practical\nconsequences. Progress in Retinal and Eye Research. 51, pp. 125 - 155. 03/2016. DOI: 10.1016/j.preteyeres.2015.07.005\n\n\nLabrador-Velandia S; Alonso-Alonso ML; Di Lauro S; García-Gutierrez MT; Srivastava GK; Pastor JC; Fernandez-Bueno I. Mesenchymal stem cells provide paracrine neuroprotective resources that delay degeneration of co-cultured organotypic neuroretinal cultures.Experimental Eye Research. 185, 17/05/2019. DOI: 10.1016/j.exer.2019.05.011\n\nSalvatore Di Lauro; Maria Teresa Garcia Gutierrez; Ivan Fernandez Bueno. Quantification of pigment epithelium-derived factor (PEDF) in an ex vivo coculture of retinal pigment epithelium cells and neuroretina.\nJournal of Allbiosolution. 2019. ISSN 2605-3535\n\nSonia Labrador Velandia; Salvatore Di Lauro; Alonso-Alonso ML; Tabera Bartolomé S; Srivastava GK; Pastor JC; Fernandez-Bueno I. Biocompatibility of intravitreal injection of human mesenchymal stem cells in immunocompetent rabbits. Graefe's archive for clinical and experimental ophthalmology. 256 - 1, pp. 125 - 134. 01/2018. DOI: 10.1007/s00417-017-3842-3\n\n\nSalvatore Di Lauro, David Rodriguez-Crespo, Manuel J Gayoso, Maria T Garcia-Gutierrez, J Carlos Pastor, Girish K Srivastava, Ivan Fernandez-Bueno. A novel coculture model of porcine central neuroretina explants and retinal pigment epithelium cells. Molecular Vision. 2016 - 22, pp. 243 - 253. 01/2016.\n\nSalvatore Di Lauro. Classifications for Proliferative Vitreoretinopathy ({PVR}): An Analysis of Their Use in Publications over the Last 15 Years. Journal of Ophthalmology. 2016, pp. 1 - 6. 01/2016. DOI: 10.1155/2016/7807596\n\nSalvatore Di Lauro; Rosa Maria Coco; Rosa Maria Sanabria; Enrique Rodriguez de la Rua; Jose Carlos Pastor. Loss of Visual Acuity after Successful Surgery for Macula-On Rhegmatogenous Retinal Detachment in a Prospective Multicentre Study. Journal of Ophthalmology. 2015:821864, 2015. DOI: 10.1155/2015/821864\n\nIvan Fernandez-Bueno; Salvatore Di Lauro; Ivan Alvarez; Jose Carlos Lopez; Maria Teresa Garcia-Gutierrez; Itziar Fernandez; Eva Larra; Jose Carlos Pastor. Safety and Biocompatibility of a New High-Density Polyethylene-Based\nSpherical Integrated Porous Orbital Implant: An Experimental Study in Rabbits. Journal of Ophthalmology. 2015:904096, 2015. DOI: 10.1155/2015/904096\n\nPastor JC; Pastor-Idoate S; Rodríguez-Hernandez I; Rojas J; Fernandez I; Gonzalez-Buendia L; Di Lauro S; Gonzalez-Sarmiento R. Genetics of PVR and RD. Ophthalmologica. 232 - Suppl 1, pp. 28 - 29. 2014\n\nRodriguez-Crespo D; Di Lauro S; Singh AK; Garcia-Gutierrez MT; Garrosa M; Pastor JC; Fernandez-Bueno I; Srivastava GK. Triple-layered mixed co-culture model of RPE cells with neuroretina for evaluating the neuroprotective effects of adipose-MSCs. Cell Tissue Res. 358 - 3, pp. 705 - 716. 2014.\nDOI: 10.1007/s00441-014-1987-5\n\nCarlo De Werra; Salvatore Condurro; Salvatore Tramontano; Mario Perone; Ivana Donzelli; Salvatore Di Lauro; Massimo Di Giuseppe; Rosa Di Micco; Annalisa Pascariello; Antonio Pastore; Giorgio Diamantis; Giuseppe Galloro. Hydatid disease of the liver: thirty years of surgical experience.Chirurgia italiana. 59 - 5, pp. 611 - 636.\n(Italia): 2007. ISSN 0009-4773\n\nChapters in books\n\t\n' Salvador Pastor Idoate; Salvatore Di Lauro; Jose Carlos Pastor Jimeno. PVR: Pathogenesis, Histopathology and Classification. Proliferative Vitreoretinopathy with Small Gauge Vitrectomy. Springer, 2018. ISBN 978-3-319-78445-8\nDOI: 10.1007/978-3-319-78446-5_2. \n\n' Salvatore Di Lauro; Maria Isabel Lopez Galvez. Quistes vítreos en una mujer joven. Problemas diagnósticos en patología retinocoroidea. Sociedad Española de Retina-Vitreo. 2018.\n\n' Salvatore Di Lauro; Salvador Pastor Idoate; Jose Carlos Pastor Jimeno. iOCT in PVR management. OCT Applications in Opthalmology. pp. 1 - 8. INTECH, 2018. DOI: 10.5772/intechopen.78774.\n\n' Rosa Coco Martin; Salvatore Di Lauro; Salvador Pastor Idoate; Jose Carlos Pastor. amponadores, manipuladores y tinciones en la cirugía del traumatismo ocular.Trauma Ocular. Ponencia de la SEO 2018..\n\n' LOPEZ GALVEZ; DI LAURO; CRESPO. OCT angiografia y complicaciones retinianas de la diabetes. PONENCIA SEO 2021, CAPITULO 20. (España): 2021.\n\n' Múltiples desprendimientos neurosensoriales bilaterales en paciente joven. Enfermedades Degenerativas De Retina Y Coroides. SERV 04/2016. \n' González-Buendía L; Di Lauro S; Pastor-Idoate S; Pastor Jimeno JC. Vitreorretinopatía proliferante (VRP) e inflamación: LA INFLAMACIÓN in «INMUNOMODULADORES Y ANTIINFLAMATORIOS: MÁS ALLÁ DE LOS CORTICOIDES. RELACION DE PONENCIAS DE LA SOCIEDAD ESPAÑOLA DE OFTALMOLOGIA. 10/2014.",institutionString:null,institution:null},{id:"243698",title:"Dr.",name:"Xiaogang",middleName:null,surname:"Wang",slug:"xiaogang-wang",fullName:"Xiaogang Wang",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/243698/images/system/243698.png",biography:"Dr. Xiaogang Wang, a faculty member of Shanxi Eye Hospital specializing in the treatment of cataract and retinal disease and a tutor for postgraduate students of Shanxi Medical University, worked in the COOL Lab as an international visiting scholar under the supervision of Dr. David Huang and Yali Jia from October 2012 through November 2013. Dr. Wang earned an MD from Shanxi Medical University and a Ph.D. from Shanghai Jiao Tong University. Dr. Wang was awarded two research project grants focused on multimodal optical coherence tomography imaging and deep learning in cataract and retinal disease, from the National Natural Science Foundation of China. He has published around 30 peer-reviewed journal papers and four book chapters and co-edited one book.",institutionString:null,institution:null},{id:"7227",title:"Dr.",name:"Hiroaki",middleName:null,surname:"Matsui",slug:"hiroaki-matsui",fullName:"Hiroaki Matsui",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Tokyo",country:{name:"Japan"}}},{id:"312999",title:"Dr.",name:"Bernard O.",middleName:null,surname:"Asimeng",slug:"bernard-o.-asimeng",fullName:"Bernard O. Asimeng",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Ghana",country:{name:"Ghana"}}},{id:"318905",title:"Prof.",name:"Elvis",middleName:"Kwason",surname:"Tiburu",slug:"elvis-tiburu",fullName:"Elvis Tiburu",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Ghana",country:{name:"Ghana"}}},{id:"336193",title:"Dr.",name:"Abdullah",middleName:null,surname:"Alamoudi",slug:"abdullah-alamoudi",fullName:"Abdullah Alamoudi",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Majmaah University",country:{name:"Saudi Arabia"}}},{id:"318657",title:"MSc.",name:"Isabell",middleName:null,surname:"Steuding",slug:"isabell-steuding",fullName:"Isabell Steuding",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Harz University of Applied Sciences",country:{name:"Germany"}}},{id:"318656",title:"BSc.",name:"Peter",middleName:null,surname:"Kußmann",slug:"peter-kussmann",fullName:"Peter Kußmann",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Harz University of Applied Sciences",country:{name:"Germany"}}}]}},subseries:{item:{id:"19",type:"subseries",title:"Animal Science",keywords:"Animal Science, Animal Biology, Wildlife Species, Domesticated Animals",scope:"The Animal Science topic welcomes research on captive and wildlife species, including domesticated animals. The research resented can consist of primary studies on various animal biology fields such as genetics, nutrition, behavior, welfare, and animal production, to name a few. 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