\r\n\tRadiation monitoring deals with the sampling and measurement of different products found in different radiation pathways from the environment ending with consumption in humans. Gamma-spectroscopy is the main tool for measurement of these radiations.
\r\n
\r\n\tThe aim of this book is to investigate the radionuclide concentrations in the most consumable food products, air, water and soil. Particularly, it is essential to investigate the radiations level in the surroundings of a nuclear facility.
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\n
1. Introduction
\n
Since first AC current high‐power hydropower plant was put in operation, built by Nikola Tesla and George Westinghouse in 1895 on Niagara Falls, electrification of the world is dramatically changed. The growing power demand and energy consumption in the last decades require fundamental changes in the process, power production and services. These requirements tend to use both conventional and nonconventional energy generation in order to have power plants useful both economically and environmental friendly to the society. Although new trends in this field focus on producing clean energy from renewable sources, the world’s most used fuel in power plants is still coal with 41% of produced global electricity [1]. Coal, oil, nuclear and gas power plants are still dominant for supplying base load in all power grids. Also, energy consumed at power plants for generating electricity is still high. Based on OECD data [2], the amount of electricity supplied to the final consumers was 33% of the total energy consumed at power plants.
\n
In Europe, the largest share of budget spent on research, development and demonstration (RD&D) on energy technology was in energy efficiency and renewable sources [3]. On the other side, in Japan, 39% share of total energy RD&D in 2015 remains in the field of nuclear energy [3]. Regarding nuclear power plant (NPP), more attention is spent on improving safety, especially after accident in Fukushima NPP in March 2011.
\n
\n
\n
2. Energy efficiency and reliability
\n
Improving energy efficiency and reliability goes in several ways. Some of the solutions are to continuously monitor and supervise vital equipment in power plants, like generator transformers, in order to improve maintenance and reduce costs. Additional advantage is decision support, where results taken from online monitoring systems are analyzed by external experts that help plant staff and management to make decision about plant operation when some of the possible malfunction of transformers is detected or expected [4]. This also could yield to proper time schedule of transformer replacement [5].
\n
Modern control systems in power plants cannot be realized without the modern system of monitoring of process parameters or parameters of machines and systems. Continuous monitoring includes continuous monitoring of machine operation (online), automatic storage of information and the possibility of automatic or subsequent processing and analysis. It also includes the generation of specific alarms and their submission to the operator and control system, according to a certain procedure [6]. Diagnostics of the generator are based on a wide range of data from off‐line and online testing generators and data analysis. All test data, operating data and data of the machine are stored in a database for generators. Thus, all test data from any laboratory, repairs, unexpected events and failures are available for analysis. The data in the database with each successive inspection and testing are updated. The database is very flexible and has the ability to expand for all possible new types of tests, acquisition of photo records of visual inspections and so on [7].
\n
\n
\n
3. Operation improvement and stability
\n
In virtually all coal preparation operations, mill systems are a critical part of the process to provide economical, reliable and energy‐efficient grinding. Operating mills at a slightly lower speed or even a slightly higher speed than line frequency give process engineers the advantage of the mills being optimized for the grade of material and desired throughput of the final process [8]. To get the target boiler power increase in order for 5–10% of rated power, it is necessary to increase the fuel intake and one of the possibilities for that is the coal grinding mill capacity increase [9]. Proposed solution in Ref. [9] is based on enhanced motor voltage supply by increasing frequency, what is possible by medium voltage (MV) inverter. The main goal is to supply motor with rated voltage and frequency in range between 50 and 55 Hz to obtain increase of plant power for 10% by increasing grinding mill capacity. Additional benefits are reduced mechanical stress during start‐up and the additional possibility of mill slow running for inspection purposes.
\n
In order to improve power plant stability while operating close to its capability limits, as a requirement of a deregulated electricity market, one solution could be to optimally coordinate the synchronous generators’ reactive power outputs in order to maintain the total reactive power delivered by a steam power plant (SPP) or the voltage at a steam power plant high voltage (HV) busbar [10]. In such way, it is possible to aggregate the multimachine power plant into single virtual generator, thus enabling more sophisticated zonal voltage control across power transmission network.
\n
\n
\n
4. Environmental impacts
\n
Environmental impacts of power plants are mainly reflected in emissions of pollutants and greenhouse gases from fossil fuel‐based electricity generation. For instance, electricity generation is the fourth highest combined source of NOx, carbon monoxide and particulate mvatter in the United States [11]. The combustion of coal for power generation produces fly ash, which must be collected prior to discharge to the atmosphere. Electrostatic precipitators are devices used for collecting of fly ash from smoke gases in power plants that use coil as a combustion fuel. The precipitator collection efficiency can be expected to exceed 99.5%. Most existing electrical precipitators are developed with classical continual power supply that provides DC voltage at the end of electrodes. Improvement of this power supply type that has better purification and overall energy efficiency is obtained by the usage of intermittent supply [12].
\n
\n
\n
5. Renewables and clean fuels
\n
But, not only fossil fuel power plants affect on the environment. Renewable sources like small hydropower plants and wind farms could have significant influence on fish and bird habitats and migrations. The strategic environmental assessment can be considered as the most important, the most general and the most comprehensive instrument for directing the strategic planning process toward the principles and objectives of environmental protection, as well as for making optimum decisions on future sustainable spatial development, especially in energy sector [13].
\n
Hydrogen is the most abundant element and cleanest fuel in the universe. Unlike hydrocarbon fuels that produce harmful emissions, hydrogen fuel produces pure water as the only by‐product. Low‐cost photoelectrochemical process efficiently uses sunlight to separate hydrogen from any source of water to produce clean and environmental friendly renewable hydrogen. Innovative solar hydrogen generator eliminates the need for conventional electrolyzers, which are expensive and energy intensive.
\n
\n
\n
6. Conclusion
\n
All of the above takes the attention of researchers to continuously work on solutions for better fuel usage and energy efficiency improvement, while producing more electricity with higher reliability and safety and lower impact to the environment. The aim of this book is to assist researches involved in power plant design and development, as well industrial engineers involved in plant’s maintenance with recent techniques taken from different technologies and disciplines.
\n
\n\n',keywords:null,chapterPDFUrl:"https://cdn.intechopen.com/pdfs/56217.pdf",chapterXML:"https://mts.intechopen.com/source/xml/56217.xml",downloadPdfUrl:"/chapter/pdf-download/56217",previewPdfUrl:"/chapter/pdf-preview/56217",totalDownloads:1166,totalViews:113,totalCrossrefCites:0,totalDimensionsCites:0,totalAltmetricsMentions:0,impactScore:0,impactScorePercentile:51,impactScoreQuartile:3,hasAltmetrics:0,dateSubmitted:"April 13th 2017",dateReviewed:"June 1st 2017",datePrePublished:null,datePublished:"July 13th 2017",dateFinished:"June 24th 2017",readingETA:"0",abstract:null,reviewType:"peer-reviewed",bibtexUrl:"/chapter/bibtex/56217",risUrl:"/chapter/ris/56217",book:{id:"5807",slug:"recent-improvements-of-power-plants-management-and-technology"},signatures:"Aleksandar B. Nikolic and Zarko S. Janda",authors:[{id:"19724",title:"Dr.",name:"Aleksandar",middleName:"B",surname:"Nikolic",fullName:"Aleksandar Nikolic",slug:"aleksandar-nikolic",email:"anikolic@ieent.org",position:"President of Scientific Council",profilePictureURL:"https://mts.intechopen.com/storage/users/19724/images/5117_n.jpg",institution:null}],sections:[{id:"sec_1",title:"1. Introduction",level:"1"},{id:"sec_2",title:"2. Energy efficiency and reliability",level:"1"},{id:"sec_3",title:"3. Operation improvement and stability",level:"1"},{id:"sec_4",title:"4. Environmental impacts",level:"1"},{id:"sec_5",title:"5. Renewables and clean fuels",level:"1"},{id:"sec_6",title:"6. Conclusion",level:"1"}],chapterReferences:[{id:"B1",body:'\nOECD. OECD Factbook 2015-2016: Economic, Environmental and Social Statistics. Paris: OECD Publishing; 2016. DOI: 10.1787/factbook‐2015‐en\n'},{id:"B2",body:'\nInternational Energy Agency. Key OECD Electricity Trends 2016. Available from: http://www.iea.org/media/statistics/Keyelectricitytrends2016_.pdf\n\n'},{id:"B3",body:'\nInternational Energy Agency. Key Trends on Energy Technology RD&D Budgets. 2016 Edition. Available from: http://www.iea.org/media/statistics/topics/IEA_RDD_Factsheet_2016.pdf\n\n'},{id:"B4",body:'\nNikolic A, Pejovic B, Djuric B, Jankovic J, Drakic K. Maintenance improvement and cost reduction of large scale systems using remote monitoring and supervision. In: Proceedings of 2nd International Conference on Intelligent Control, Modelling and Systems Engineering (ICMS ‘14); 29-31 January 2014; Cambridge, MA, USA. pp. 229-235. WSEAS Press, 2014. ISSN: 2227-4588, ISBN: 978-960-474-365-0\n'},{id:"B5",body:'\nDe Wachter B. Transformer Replacement Decisions. Application Note. ECI Publication No. Cu0185; November 2013\n'},{id:"B6",body:'\nHan Y, Song YH. Condition monitoring techniques for electrical equipment – A literature survey. IEEE Transactions on Power Delivery. 2003;18(1):4-13\ufeff\ufeff\n'},{id:"B7",body:'\nKartalovic N, Babic B, Marinkovic S, Teslic D, Nikolic A. Monitoring and diagnostic center for generators. In: Proceedings of 2nd International Conference on Intelligent Control, Modeling and Systems Engineering (ICMS ‘14); 29-31 January 2014; Cambridge, MA, USA. pp. 151-155. WSEAS Press, 2014. ISSN: 2227-4588, ISBN: 978-960-474-365-0\n'},{id:"B8",body:'\nHanna RA and Prabhu S. “Medium-voltage adjustable-speed drives-users’ and manufacturers’ experiences,” in IEEE Transactions on Industry Applications, 33(6):pp. 1407-1415, Nov/Dec 1997. doi: 10.1109/28.649949\n'},{id:"B9",body:'\nJanda Z, Nikolic A. MV variable speed drive for coal mill capacity improvement. In: Proceedings of 16th International Symposium on Power Electronics – Ee 2011; Paper No. T4-2.10, pp. 1-4. October 26th - 28th, 2011. Power Electronics Society, Novi Sad Serbia\n'},{id:"B10",body:'\nDragosavac J, Janda Z, Milanovic JV, Mihailovic L, Radojicic B. Practical implementation of coordinated Q‐V control in a multi‐machine power plant. IEEE Transactions on Power Systems. 2014;29(6):2883-2891. DOI: 10.1109/TPWRS.2014.2318794\n'},{id:"B11",body:'\nUnited States Environmental Protection Agency. Climate Change Indicators in the United States: Global Greenhouse Gas Emissions. 2016. Available from: https://www.epa.gov/climate‐indicators\n\n'},{id:"B12",body:'\nParker K. Electrical Operation of Electrostatic Precipitators. London: The Institution of Electrical Engineers; 2003\n'},{id:"B13",body:'\nNilssona M, Björklundb A, Finnveden G, Johanssonc J. Testing a SEA methodology for the energy sector: A waste incineration tax proposal. Environmental Impact Assessment Review. 2005;25:1-32. DOI: 10.1016/j.eiar.2004.04.003\n'}],footnotes:[],contributors:[{corresp:"yes",contributorFullName:"Aleksandar B. Nikolic",address:"anikolic@ieent.org",affiliation:'
Electrical Engineering Institute Nikola Tesla, University of Belgrade, Belgrade, Serbia
'},{corresp:null,contributorFullName:"Zarko S. Janda",address:null,affiliation:'
Electrical Engineering Institute Nikola Tesla, University of Belgrade, Belgrade, Serbia
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1. Introduction
After 40 years of the discovery of the human immunodeficiency virus (HIV) that causes autoimmune deficiency disease syndrome (AIDS), HIV remains a critical public health concern, particularly among racial/ethnic and sexual/gender minority populations. During the intervening years, there have been enormous advances in biomedical prevention strategies (e.g., pre-exposure prophylaxis (PrEP) and treatment therapies antiretroviral therapy (ART) that have transformed HIV from a death sentence to a chronic condition. Yet, despite these lifesaving treatments and therapies, the benefits have not been equally shared. There are still alarming numbers of new infections disproportionately impacting racial/ethnic and sexual/gender minorities, particularly Black gay and bisexual men in the United States. Notably, Blacks represent less than 13% of the population, but Black MSM accounts for 42% of all new HIV infections [1]. There are marked racial/ethnic disparities in health in the US, with Blacks or African-Americans faring substantially worse compared to their white counterparts, including diabetes prevalence, colorectal cancer incidence and death, and mortality due to coronary heart disease and stroke [2, 3, 4]. These disparities are particularly acute in HIV, particularly for Black men who have sex with men (Black MSM). It is estimated half of Black MSM in the U.S. can be expected to become HIV positive in their lifetime [5]. Current surveillance data show that most of the HIV cases are clustered in the Southern U.S., a region marked by racial and structural inequalities as a result of racialized chattel slavery and Jim Crow segregation, where a large majority of the Black population continues to live in neighborhoods, that are divided and unequal reflecting previously codified racial divisions in housing, employment, education, healthcare, public utilities, and infrastructure [6].
While studies have shown African Americans do not have higher rates of sexual risk behaviors than their white counterparts and biomedical advances are effective at prevention and transmission of HIV/AIDS, at issue is accounting for the enormous racial/ethnic disparities in HIV-related outcomes [7]. In this perspective chapter, we explore the evidence underpinning the relationship between structural racism and high rates of HIV among racial and sexual minority populations in the U.S., particularly Black men who have sex with men (MSM). We examine the social, economic, and political policies and practices that engender a social and structural, and built environment that may increase or reduce an individual’s HIV vulnerability to exposure to HIV. An examination of structural racism and HIV is timely given the ongoing debates around race and Covid-19, the Black lives matter movement and the ending the HIV epidemic initiative [8, 9, 10]. This work builds on previous work on race and HIV by incorporating emerging research employing an intersectional lens to understand the role of multiple identities and interlocking oppressions in explaining differential outcomes around HIV [11, 12, 13]. Frist we will review the origins of HIV using a social-ecological lens to better understand the influence of structural factors on increasing barriers to HIV prevention, care, and treatment services among racial/ethnic and sexual/gender minorities. Next, we provide an overview of the types of structural racism followed by a description of the intersectional stigma framework that underpins our conceptualization of how structural racism operates to increase HIV vulnerability. Then we embark on a review of the literature providing evidence linking structural racism and HIV-related disparities. Finally, we end with conclusions, key policy recommendations, and future directions of research to address the unique needs and structural barriers that create the conditions ripe for HIV to flourish among racial and sexual minority populations. While this chapter focuses primarily on the experience of Black sexual minority men in the U.S., it is our hope this information will have broader relevance to other populations and settings to inform the development and implementation of structural level programs and interventions to reduce the number of new infections among racial/ethnic and sexual/gender minority populations, both in the U.S. and beyond.
2. Understanding the structural origins of the HIV epidemic
Significant success in the prevention of HIV infection in the United States has been achieved. However, those successes were hard-won with significant opposition from hostile government officials, religious groups, and the public at large. In the early days of the AIDS epidemic, there was widespread misinformation about AIDS with many believing it was a disease that affected only homosexuals and was a punishment from God for their turning away from the teachings of the Bible. Alongside these common misinterpretations, longstanding homophobia and anti-gay stigma and discrimination were the norm. It was within this socio-political context of government inaction and societal scapegoating where HIV went undiagnosed and untreated and allowed to flourish within the Black community, particularly among Black MSMs.
Much of the initial response was largely limited to activities organized by LGBT community-based organizations and the gay community focusing primarily on behavioral change and lifestyle factors including harm reduction (e.g., drug and substance use, sexual risk behavior) or uptake of biomedical therapies (e.g., condoms). The first community-led activities were launched in San Francisco and New York City where the first cases of HIV occurred [14]. These early activities were designed to increase awareness and to educate the gay community about how the virus is transmitted and risk reduction strategies to prevent HIV.
As time progressed, the government stepped in launching HIV prevention programs to reduce the spread of the disease. These early government initiatives led by the CDC continued the focus on individual-level programming around behavioral change including: (1) the development of the National AIDS Information Line (1983), (2) National AIDS Clearinghouse (1987), (3) America Responds to AIDS, a national public information campaign (1987), and (4) the development and dissemination of Understanding AIDS (1988). Understanding AIDS was groundbreaking, being the first public education campaign utilizing the U.S. postal service to deliver health literacy information to every home in the United States [15]. However, early approaches in delivering basic HIV education and awareness, changing attitudes, and harm reduction among most-at-risk populations often did not address the unique needs and realities of racial/ethnic communities. These programs targeted priority populations deem at elevated risk including high-school and college-aged persons, pregnant women, and healthcare workers [16]. While important advances were made in the gay community benefitting the white gay community, however, they did not substantially reduce HIV risk for African American and LatinX communities. In the late 1980s, we start to see the development of more targeted evidence-based interventions such as the five-city CDC AIDS Community Demonstration Projects (1989), CDC HIV Prevention Research Synthesis Project, and the CDC Diffusion of Effective Behavioral Interventions (DEBI) project [17, 18]. While these studies and interventions were more tailored for marginalized populations such as injection drug uses, sex workers, and racial/ethnic minorities, they were primarily individual-level behavioral change initiatives with only a few structural interventions.
3. A conceptual framework for the association between structural racism and HIV
Researchers in the area of public health, sociology, geography, and urban planning have shown macro-level factors at the structural level can influence health on a number of health-related outcomes including mental health, cardiovascular disease, maternal health, diabetes, and HIV [19, 20, 21, 22, 23, 24, 25, 26]. According to Link and Phelan in their theory of fundamental causes they argue that structural factors, that is, socioeconomic status (SES) contribute to inequalities in health [27]. Extrapolating from this premise and building on socio-ecological frameworks, we posit that the broader dynamic and interactive macro-level social, political, and economic processes structure access to societal resources and opportunity structures which are mediated through the built environment has profound consequences influencing sexual risk behavior and access to HIV prevention, care and treatment services. Our model draws inspiration from the following structural frameworks: Structural violence, social determinants of health, neighborhood effects, weathering and intersectionality [13, 28, 29, 30]. Each of these theories and frameworks center upstream, macro-level factors as foundational to health disparities and provides a useful conceptual lens to understand the spatial legacies of chattel slavery and contemporary effects of racial capitalism and structural racism. Farmer’s theory of structural violence emerged from Paul Farmer’s groundbreaking work in HIV in Haiti and argues that structural consequences, for example, slavery, colonialism, Jim Crow, and other forms of oppression have profound material consequences for individuals and populations, particularly racial and ethnic minorities. Next, social determinants of health argues that unequal access to basic needs and resources (i.e., employment, education, housing, and healthcare) disadvantages certain individuals and groups affecting their health outcomes [28]. Diex Roux’s neighborhood effects framework highlights the importance of spatial and geographical variations in health arguing the larger structural environment shapes neighborhood/community conditions and features that may influence health outcomes [29]. Finally, we include Geronimus’ Theory of weathering which helps us to better understand how effects of structural racism (e.g., residential segregation, poor-quality schools, environmental racism) ‘gets under the skin’ creating stress in the form of allostatic load which has been shown to affect health outcomes [30]. These active and ongoing adjustments necessary to manage these multiple interacting structural forces and stressors can create wear and tear on the body leading to poor health outcomes, particularly increasing HIV vulnerability for historically marginalized and stigmatized groups such as Black MSM. Moreover, we employ an intersectional approach to emphasize the intersections of multiple and intersecting identities (e.g., race, gender, and sexual orientation) and interlocking systems of oppression (e.g., racism, homophobia, and classism) that may influence an individual’s behavior and access to resources and opportunities that impact their health and well-being [11, 12, 13]. By utilizing an intersectional perspective, it allows us to center the multiple stigmatized identifies and contend with the insidious and harmful direct effects of intentional and unintentional state-sanctioned race-based, structural factors and processes that distribute resources and opportunities that increase HIV vulnerability for Black sexual minority men. Our conceptual model presented in Figure 1 is informed by the aforementioned socioecological frameworks and divided into three levels: (1) structural level, (2) neighborhood level, and (3) individual level, representing the multilevel and multivalent nature of structural racism. The structural level is defined as macro-level forces (e.g., social, political, economic, and legal policies) developed by governments and powerful institutions that govern the organization and structure of society. The structural racism interpretation of HIV proposes that macro-level structural level forces are paramount in understanding HIV-related health disparities and as such foundational to explaining differential HIV-related outcomes. Neighborhood level refers to the community environment including both social and built environment aspects of neighborhoods. The construct of the neighborhood is derived from the neighborhood effects framework which explicitly acknowledges that relative deprivation in the form of neighborhood structural disadvantage (e.g., access to employment, housing, public transportation, etc.) may influence health-seeking behavior and limit access to HIV prevention, care, and treatment services. Finally, the individual level includes both sociodemographic characteristics (e.g., race, gender, age, and education) and risk factors (e.g., condom use, number of sexual partners) that are derived out of an unequal distribution of resources and exposure that create barriers to healthy behaviors and access to healthcare. Illustrated in Figure 1 are pathways that are represented by arrows in the diagram modeling key risk factors theorized as having a significant impact on HIV vulnerability and explaining differential HIV-related outcomes, particularly among Black MSM. The arrows indicate the dynamic and interactive nature of structural racism which has both direct and moderating effects that either reduce or increase an individual’s exposure to HIV.
Figure 1.
Structural racism and HIV vulnerability conceptual framework.
4. Evidence linking structural racism and HIV
While there is growing recognition of structural racism and its impact on health, yet there is limited research examining the relationship between structural level factors impact on health HIV-related outcomes. A full accounting of structural racism and HIV disparities among sexual and racial minorities is beyond the scope of this chapter; rather instead we will provide an overview of the research focusing on the role of structural racism in fostering conditions that increase HIV vulnerability for Black MSM. We also acknowledge there is significant diversity within the Black MSM rubric (e.g., gay, bisexual, transgender, gender non-conforming; and same-gender-loving) with each subgroup experiencing varying levels of structural racism at the intersection of race, class, sexual, and gender identity, gender expression and HIV. Several researchers have critiqued the use of the term MSM because of who it includes and excludes, however again due to the limited scope of this chapter, we use the more traditional definition of Black MSM—an individual who identifies as Black or African American, assigned male at birth (MAB) and gay, bisexual and other men who have sex with other men [31, 32, 33]. In this section, we divide structural racism into five key domains: (1) Neighborhood Effects, (2) Social Determinants of Health, (3) Access to HIV Prevention Care and Treatment Services, (4) Incarceration, Criminal Justice System and HIV, and (5) Stigma, Cultural Competency, and Medical Mistrust. We will attempt to address each in turn.
5. Neighborhood effects and HIV
Research has shown characteristics of the neighborhood can shape HIV risk environments with differential impacts, particularly among sexual and racial/ethnic minority populations [34, 35, 36, 37, 38, 39, 40]. Segregated residential patterns concentrate high rates of HIV and community viral load in a small geographical region increasing a person’s likelihood of having a sex partner who is HIV-positive and not virally suppressed [41, 42, 43]. A study of Black MSM in Chicago found that an additional infected person into your sexual network increases the odds of seroconversion by a factor of thirteen [43]. The Chicago Metropolitan Statistical Area is ranked 5th in the nation with a dissimilarity score of 83.6. The index of dissimilarity is a measure of residential segregation that measures how one racial group is distributed across census tracts in the metropolitan area compared to the other group. Scores ranging from 0 to 100 with a value of 60 or above is considered very high. In Chicago, a score of 76.9 indicates a high level of segregation which aligns with low viral suppression rates, thereby increasing HIV vulnerability for Black MSM [44]. Residential segregation has also been shown to affect the choice of sexual partner’s by limiting their social network contributing to increased levels of HIV transmission and susceptibility among the Black MSM population. A study of the effect of partner characteristics on HIV infection in Los Angeles found Black MSM are more likely to have Black sexual partners than other groups, thus increasing their potential of encountering an HIV-positive sexual partner [45]. In this study, Black MSM were 4.4 times more likely to be HIV positive than their white counterparts. Moreover, data suggest an association with neighborhood conditions and HIV-related outcomes. Another study of Black MSM residing in New York City found a measure of neighborhood physical disorder (e.g., boarded up and vacant housing) was associated with lower odds of serodiscordant condom less intercourse (AOR = 0.43; 95% CI 0.19, 0.95) among Black MSM suggesting the physical environment foster conditions and situations that influence sexual risk behavior [46].
6. Social determinants of health
Poverty-related factors (e.g., low-income, unstable housing, incarceration, etc.) have been shown to be a driver of the HIV epidemic creating significant barriers to access to HIV prevention services and poorer HIV-related outcomes [47, 48, 49]. Housing instability has been shown to be negatively associated with risk of HIV infection; viral suppression and uptake and retention of PrEP and ART [50, 51, 52]. One study of Black MSM in Massachusetts found those with unstable housing were four times more likely to report engaging in unprotected sex. A systematic review of housing status and HIV-related outcomes found lack of stable, secure, adequate housing is a significant barrier to consistent and appropriate HIV medical care, access and adherence to antiretroviral medications, sustained viral suppression, and risk of forward transmission [53]. In a recent six-city study of Black MSM, 12.1% had experienced homelessness in the last 12 months and reported difficulty in maintaining adherence to ART compared to stably housed respondents [54]. Millet et al. found housing instability, income, and marijuana use explained higher rates of HIV among Blacks compared to whites [44]. In another study of Black MSM in Atlanta, one-third of respondents reported experiencing unstable housing with the majority of those being homeless [55]. Being unstably housed was associated with declines in viral suppression. In addition to housing, the study found living below the federal poverty level, and being incarcerated in the last 12 months was also associated with statistical differences in viral suppression between Black and White MSM [55]. For many racial/ethnic and sexual gender minorities maintaining health-promoting behaviors and/or medication regimens such as PrEP compete with other survival needs, such as securing stable housing.
7. Access to HIV prevention care and treatment services
Historically, African Americans have faced significant challenges obtaining affordable, quality healthcare and often delaying seeking healthcare resulting in an expensive emergency room visit and increased morbidity and mortality [56]. Due to their stigmatized and marginalized status as Black, gay and poor, Black MSM in particular face a myriad number of challenges to accessing affordable culturally competent, quality healthcare across the HIV continuum. Access and uptake of HIV prevention biomedical therapies (e.g., HIV testing, pre-exposure prophylaxis (PrEP), and antiretroviral therapy (ART)) is essential to improving HIV-related outcomes for people living with HIV (PLWIH) and as an effective HIV prevention strategy to eliminate transmission of HIV [57]. However studies show Black men are less likely to use ART and have low rates of adherence. In 2017, a study found Black MSM were less likely to secure ART, after controlling for less education, lower-income and access to healthcare [58]. Pre-exposure prophylaxis (PrEP), which has been found to be highly effective at reducing the transmission of HIV, remains alarmingly low among Black MSM [59]. A recent study found approximately 500,000 African Americans could benefit from PrEP, but only 7000 prescriptions (0.014%) were filled [60]. Several studies have found Black MSM are less likely to use PrEP than their White counterparts [61, 62]. For example, a study utilizing the National HIV Behavioral Surveillance survey conducted in San Francisco among MSM showed only 7.7% of Blacks used PrEP compared to 22.9% of their White counterparts.
There is growing evidence that suggests structural racism-related access to social and economic resources affects access to HIV prevention, care, and treatment programs among Black MSM. Numerous studies have shown Black MSM face significant barriers to accessing health insurance. In a meta-analysis of risk factors associated with disparities in HIV infection among MSM in Canada, UK, and the USA, Millet e al. found Black MSM were less likely to have health insurance compared to their white counterparts [63]. In this same study, the authors found pronounced disparities across a number of structural barriers that increase HIV vulnerability for Black MSM. Black MSM was more likely to be unemployed, have low educational attainment, have lower income, and ever been incarcerated which exacerbate efforts to obtain healthcare. A study examining access to healthcare found expansion of Medicaid was associated with a decline in new HIV diagnoses [64]. A recent study of Black MSM found 31% had no access to health insurance [65]. Another study found an association between having health insurance and being unaware of one’s HIV status demonstrating the importance of having a primary healthcare provider [66].
8. Incarceration, criminal justice system and HIV
There is growing recognition that incarceration is a major structural factor in increasing HIV vulnerability among Black MSM. Structural inequities in the criminal justice system (e.g., stop and frisk, race-based sentencing, bail bonds) have led to disparities in incarceration rates for racial/ethnic minorities, for both Black men and Black MSM [67, 68, 69, 70]. Research has shown correctional facilities are sties of HIV infection where HIV prevalence rates are 5 times that of the general population, yet only 20 states conduct HIV testing at the point of admission [71]. A study conducted in North Carolina showed only 31% of male inmates received a voluntary HIV test [72]. While some facilities provide HIV prevention education, it is often inconsistent [73, 74, 75]. Also, despite high rates of unprotected sex and HIV infection within the prison system, the provision of condoms is not routine. Only two state prison systems and five county jails make condoms available to their male inmates [76]. Among Black MSM inmates who reported engaging in anal sex, 90% indicated they did not use a condom [77]. Furthermore, a prior history of incarceration is associated with non-adherence to HIV treatment [78]. Over incarceration of African American men and lack of access to HIV prevention, care and treatment create conditions that drive the transmission of HIV among racial/ethnic minority populations, particularly Black MSM [79].
9. Stigma, cultural competency and medical mistrust
While having insurance and a primary healthcare provider are important in increasing access to needed HIV prevention, care, and treatment services, it does not always guarantee access. For HIV prevention therapies to be prescribed both patients and healthcare providers must be ready and willing to discuss sexual health. Institutional cultural competency and subsequent patient-provider communication have been shown to influence uptake and use of PrEP. Cultural competency and the healthcare provider at the institutional level play a critical role in creating access to HIV prevention care and treatment for Black MSM. Despite advancements in LGBT inclusion and rights, many healthcare providers lack awareness and sensitivity in relation to sexual and gender minorities, particularly Black MSM. Evidence has shown healthcare providers often fail to discuss sexual health as a part of routine medical care which can lead to missed opportunities for critical HIV prevention education, testing, and counseling [66].
Additionally, stigma and discrimination in healthcare settings have been shown to create barriers to care among Black MSM [80, 81, 82]. Black MSM who experience institutional racism or health care provider stigma and discrimination are less likely to engage in health-seeking behavior [83, 84]. Research has shown stigma is not only a deterrent to accessing care, but it can lead to longer lapses in care among those who experience it [85, 86, 87, 88, 89, 90, 91].
10. Conclusions
There is a growing recognition that structural racism contributes to HIV-related outcomes, particularly for Black MSM [92]. This year CDC declared structural racism a public health concern [93]. Several initiatives to advance our understanding of structural racism and its effect on health have been implemented including NIH Unite Initiative whose primary goal is to address structural racism and promote racial equity and inclusion at NIH and within the larger biomedical research enterprise [94]. In the area of HIV, NIH has recently convened an HIV-Related Intersectional Stigma Research Advances and Opportunities Working Group to develop measures and resources that better help to identify and measure HIV-related stigma and discrimination at multiple levels that pose a critical barrier to the prevention, care, and treatment of HIV; and negatively affect the quality of life in those living with HIV [95].
In an effort to build on these initiatives, we call on national, state, and local governments, policymakers, and community-based organizations to implement the following structural HIV prevention interventions to reduce the number of new infections among Black MSM, marginalized and highly stigmatized population:
10.1 Development and implementation of structural competency training and policy
While there is a growing recognition of structural factors (i.e., structural racism) in shaping HIV-related outcomes, there is an urgent need for training and implementation of structural-based programs and interventions that complement biomedical therapies that address social determinants of health to improve HIV-related outcomes among Black MSM. The importance of a culturally competent healthcare professional in providing quality health care is well established [96]. Cultural competency is an evidence-based framework utilized by healthcare care systems, agencies, and organizations that establishes a set of behaviors, attitudes, and policies that enables effective cross-cultural communication between healthcare professionals and vulnerable populations leading to improved health outcomes [97]. Similarly, there is a need for the development and implementation of structural competency training including a theoretical framework setting out a set of constructs, measures, and strategies on establishing and maintaining structural competency for health care systems and healthcare professionals.
10.2 Increase and expand HIV patient navigation services
We call for the development and implementation of patient navigation services that are culturally and structurally tailored to meet the unique needs of Black MSM who are disproportionately impacted by HIV. Evidence has shown patient navigation services increase patient engagement and patient linkage to needed HIV prevention, care, and treatment services [98, 99, 100]. Structurally-appropriate HIV services might include provision of non-clinical services, for example, transportation, clothing, food, rental assistance, housing, and workforce development. Additional research and investments in addressing social determinants of health are critical if we are to reach our goals of ending the HIV epidemic by 2030.
10.3 Implementation of innovative HIV structural interventions
There is growing evidence that structural-level interventions reduce HIV vulnerability and improve HIV-related outcomes. There are a number of HIV structural interventions that have been shown to be effective including comprehensive sex education, access to healthcare, and housing assistance. However, there are other examples that may not be widely known, we list a few here to provide you examples of novel and innovative programs that can be scaled up and/or adapted for Black MSM. The Max Clinic in Seattle, WA and Open Arms Healthcare Center (OAHCC) in Jackson, MS are two examples of health centers that have been designed to meet the needs of racial/ethnic and sexual/gender minority populations by providing culturally competent, quality healthcare across the HIV Continuum [101, 102]. Both clinics offer a range of clinical and non-clinical services. OAHCC utilizes an integrated HIV care model consisting of five care components: (1) case management, (2) HIV health care (including primary health care), (3) behavioral health care (i.e., mental and substance abuse screening and treatment), (4) adherence counseling (a pharmacist-led intervention), and (5) social support services (transportation, emergency food assistance, housing, and legal assistance). The Max clinic is based on high intensity, low threshold incentivized care model including walk-in service (no appointment necessary), primary care services, food vouchers, cash incentives, no-cost bus passes, cell phones, as well as intensive case management with cross-agency coordinated care.
10.4 Expand youth friendly HIV Services (YFHS)
Both in the U.S. and globally, adolescents and young people represent a growing share of the newly infected. In the U.S., Black youth make up one-third of the newly diagnosed [103]. There is a large body of evidence supporting the effectiveness of providing youth friendly services that improve the delivery of sexual and reproductive health services. Given youth, particularly young Black gay and bisexual men, are at elevated risk of HIV, there is an urgent need to implement HIV prevention programs targeting Black MSM early in their pre-teen years. Delivery of quality services that are tailored to young Black MSM may reduce sexual risk behavior and improve adherence to HIV prevention methods such as condoms, PrEP and ART. The WHO has implemented guidelines recommending YFHS should be accessible, acceptable, equitable, appropriate, and effective [104].
10.5 Implementation of multi-level, intersectional, trauma-informed HIV prevention, care and treatment programs and services
Due to structural racism, discrimination, and stigma, Black MSM face a myriad of traumas (e.g., poverty, early childhood adverse events, that is, sexual and/or child abuse, mental health disorder, substance disorder, environmental hazard, poor educational system, lack of healthcare, and substandard housing) which have been shown to have negative effects on an individual’s mental, physical, social, emotional, or spiritual well-being and consequently has shown to be associated with HIV vulnerability [105]. There is an urgent need for evidence-based, structural-level trauma-informed interventions to address structural racism and its effects on sexual risk behavior that increase the risk of HIV transmission. Sub-Saharan Africa has been at the forefront of the implementation of structural level, trauma-informed interventions including addressing gender norms and HIV, intimate partner violence, and the use of microfinance to reduce HIV risk among young women [106, 107, 108, 109, 110, 111].
If we are to meet the goal of ending the HIV Epidemic [112] by 2030, then we must radically shift how HIV prevention services are designed and implemented. Evidence supports the rapid roll-out and scale-up of structural-level HIV prevention programs: including comprehensive sex education, stigma reduction, universal condom availability, expanded syringe access for drug users, mental health counseling, and free access to PrEP and PEP. We call for increased investments in programs and policies that address social and structural determinants of health and fundamentally shift political and policy priorities, rethink social norms, and empower and transform historically marginalized communities. A number of structural approaches have been used or may be adapted to address racial/ethnic disparities in HIV including, free healthcare, affordable housing, a living wage, guaranteed income, reforming of the criminal justice system, early childhood education, and free tuition to college. These programs and policies from a wide range of fields and disciplines, including, education, economics, and public health could be used and adapted to address racial/ethnic disparities in HIV [113]. Figure 2 presents a conceptual model for an integrated, trauma-informed HIV service delivery system. Using an ecological framework, we construct a multilevel, intersectional trauma-informed HIV service delivery model. The fundamental premise of the model is that broader, dynamic, and interlocking oppressions derived out of a distorted, racially-determined political economy, mediated through structural level processes, increase HIV vulnerability by creating barriers to access to HIV prevention, care, and treatment. We have divided the framework into three major constructs (i.e., structural, community and individual). To date, the majority of interventions have been focused on the individual level and to lesser extent community-level interventions. We propose policymakers, researchers and public health officials increase investments in the development and implementation of structural level interventions that will complement HIV prevention efforts. The effects of structural racism are foundational to our understanding of racial/ethnic and sexual gender disparities in HIV and as such it requires a structural level, systems approach to address the underlying structural, political, and economic processes that structure HIV vulnerability for Black, sexual minority men.
Figure 2.
A multilevel, intersectional trama-informed HIV service delivery model.
Conflict of interest
PB has no conflict of interests.
Funding
N/A
Availability of data and material
Any datasets generated during and/or analyzed during the current study are not publicly available due to confidentiality concerns but are available from the corresponding author on reasonable request.
Code availability
N/A
\n',keywords:"structural racism, structural discrimination, Black MSM, men who have sex with men, MSM, Black sexual minority men, pre-exposure prophylaxis (PrEP), human immunodeficiency virus (HIV), sexual and gender minorities, racial and ethnic minorities, stigma and discrimination",chapterPDFUrl:"https://cdn.intechopen.com/pdfs/79934.pdf",chapterXML:"https://mts.intechopen.com/source/xml/79934.xml",downloadPdfUrl:"/chapter/pdf-download/79934",previewPdfUrl:"/chapter/pdf-preview/79934",totalDownloads:100,totalViews:0,totalCrossrefCites:0,dateSubmitted:"September 21st 2021",dateReviewed:"November 7th 2021",datePrePublished:"January 10th 2022",datePublished:null,dateFinished:"January 6th 2022",readingETA:"0",abstract:"Structural racism is a fundamental cause of health disparities in the United States among racial/ethnic and sexual/gender minorities. Although there are well-documented disparities in the access of HIV prevention, care, and treatment services, the impact of structural racism on HIV/AIDS remains not well understood. The purpose of this chapter is to provide a detailed description of (1) the theoretical underpinnings of the link between structural racism and HIV, (2) a review of the evidence of these associations, and (3) a culturally appropriate, trauma-informed agenda that addresses intersectional, multi-level structural racism and its myriad manifestations to reduce HIV vulnerability for racial/ethnic and sexual/gender minorities, particularly Black sexual minority men.",reviewType:"peer-reviewed",bibtexUrl:"/chapter/bibtex/79934",risUrl:"/chapter/ris/79934",signatures:"Paul A. Burns",book:{id:"10914",type:"book",title:"Effective Elimination of Structural Racism",subtitle:null,fullTitle:"Effective Elimination of Structural Racism",slug:null,publishedDate:null,bookSignature:"Dr. Erick Guerrero",coverURL:"https://cdn.intechopen.com/books/images_new/10914.jpg",licenceType:"CC BY 3.0",editedByType:null,isbn:"978-1-83969-283-3",printIsbn:"978-1-83969-282-6",pdfIsbn:"978-1-83969-284-0",isAvailableForWebshopOrdering:!0,editors:[{id:"294761",title:"Dr.",name:"Erick",middleName:null,surname:"Guerrero",slug:"erick-guerrero",fullName:"Erick Guerrero"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"}},authors:null,sections:[{id:"sec_1",title:"1. Introduction",level:"1"},{id:"sec_2",title:"2. Understanding the structural origins of the HIV epidemic",level:"1"},{id:"sec_3",title:"3. A conceptual framework for the association between structural racism and HIV",level:"1"},{id:"sec_4",title:"4. Evidence linking structural racism and HIV",level:"1"},{id:"sec_5",title:"5. Neighborhood effects and HIV",level:"1"},{id:"sec_6",title:"6. Social determinants of health",level:"1"},{id:"sec_7",title:"7. Access to HIV prevention care and treatment services",level:"1"},{id:"sec_8",title:"8. Incarceration, criminal justice system and HIV",level:"1"},{id:"sec_9",title:"9. Stigma, cultural competency and medical mistrust",level:"1"},{id:"sec_10",title:"10. Conclusions",level:"1"},{id:"sec_10_2",title:"10.1 Development and implementation of structural competency training and policy",level:"2"},{id:"sec_11_2",title:"10.2 Increase and expand HIV patient navigation services",level:"2"},{id:"sec_12_2",title:"10.3 Implementation of innovative HIV structural interventions",level:"2"},{id:"sec_13_2",title:"10.4 Expand youth friendly HIV Services (YFHS)",level:"2"},{id:"sec_14_2",title:"10.5 Implementation of multi-level, intersectional, trauma-informed HIV prevention, care and treatment programs and services",level:"2"},{id:"sec_20",title:"Conflict of interest",level:"1"},{id:"sec_16",title:"Funding",level:"1"},{id:"sec_17",title:"Availability of data and material",level:"1"},{id:"sec_18",title:"Code availability",level:"1"}],chapterReferences:[{id:"B1",body:'Centers for Disease Control and Prevention. HIV and African Americans. 2019. 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DOI: 10.1016/S1055-3290(96)80006-9'},{id:"B98",body:'Mizuno Y, Higa DH, Leighton CA, Roland KB, Deluca JB, Koenig LJ. Is HIV patient navigation associated with HIV care continuum outcomes? AIDS (London, England). 2018;32(17):2557-2571. DOI: 10.1097/QAD.0000000000001987'},{id:"B99",body:'Pagkas-Bather J, Jaramillo J, Henry J, Grandberry V, Ramirez LF, Cervantes L, et al. What’s PrEP?: Peer navigator acceptability among minority MSM in Washington. BMC Public Health. 2020;20(1):248. DOI: 10.1186/s12889-020-8325-5'},{id:"B100",body:'Burns PA, Omondi AA, Monger M, Ward L, Washington R, Sims Gomillia CE, et al. Meet me where I am: An evaluation of an HIV patient navigation intervention to increase uptake of PrEP among black men who have sex with men in the deep south. Journal of Racial and Ethnic Health Disparities. 2021 Jan 5. doi: 10.1007/s40615-020-00933-1. Epub ahead of print'},{id:"B101",body:'Melvin SC, Gipson J. The open arms healthcare center’s integrated HIV care services model. Preventing Chronic Disease. 2019;(16):E135. DOI: 10.5888/pcd16.180633'},{id:"B102",body:'Dombrowski JC, Ramchandani M, Dhanireddy S, Harrington RD, Moore A, Golden MR. The max clinic: Medical care designed to engage the hardest-to-reach persons living with HIV in Seattle and King County, Washington. AIDS Patient Care STDS. 2018;32(4):149-156. DOI: 10.1089/apc.2017.0313'},{id:"B103",body:'CDC. HIV Among African American Youth. 2021. Available from: https://www.cdc.gov/nchhstp/newsroom/docs/factsheets/archive/cdc-youth-aas-508.pdf [Accessed: September 21, 2021]'},{id:"B104",body:'World Health Organization. Global Consultation on Adolescent Friendly Health Services: A Consensus Statement. Geneva: World Health Organization; 2001'},{id:"B105",body:'Earnshaw VA, Bogart LM, Dovidio JF, Williams DR. Stigma and racial/ethnic HIV disparities: Moving toward resilience. 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Shohel"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}]},subject:{topic:{id:"954",title:"Thermodynamics",slug:"thermodynamics",parent:{id:"158",title:"Metals and Nonmetals",slug:"metals-and-nonmetals"},numberOfBooks:2,numberOfSeries:0,numberOfAuthorsAndEditors:61,numberOfWosCitations:7,numberOfCrossrefCitations:10,numberOfDimensionsCitations:15,videoUrl:null,fallbackUrl:null,description:null},booksByTopicFilter:{topicId:"954",sort:"-publishedDate",limit:12,offset:0},booksByTopicCollection:[{type:"book",id:"8416",title:"Non-Equilibrium Particle Dynamics",subtitle:null,isOpenForSubmission:!1,hash:"2c3add7639dcd1cb442cb4313ea64e3a",slug:"non-equilibrium-particle-dynamics",bookSignature:"Albert S. 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Kim"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"7661",title:"Heat and Mass Transfer",subtitle:"Advances in Science and Technology Applications",isOpenForSubmission:!1,hash:"c29b5c2ce24925a935ca52b8344fbb99",slug:"heat-and-mass-transfer-advances-in-science-and-technology-applications",bookSignature:"Alfredo Iranzo",coverURL:"https://cdn.intechopen.com/books/images_new/7661.jpg",editedByType:"Edited by",editors:[{id:"67352",title:"Dr.",name:"Alfredo",middleName:null,surname:"Iranzo",slug:"alfredo-iranzo",fullName:"Alfredo Iranzo"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],booksByTopicTotal:2,seriesByTopicCollection:[],seriesByTopicTotal:0,mostCitedChapters:[{id:"67726",doi:"10.5772/intechopen.86322",title:"CFD Simulation of Heat and Mass Transfer for Climate Control in Greenhouses",slug:"cfd-simulation-of-heat-and-mass-transfer-for-climate-control-in-greenhouses",totalDownloads:1120,totalCrossrefCites:3,totalDimensionsCites:3,abstract:"Greenhouse plant production involves a number of processes such as transpiration, condensation, photosynthesis, and climate control. Such processes, in turn, set off mass and heat transfer phenomena that influence not only the quality and quantity of crop production but also its environmental cost. While these processes have considerably been analyzed in separate, they strongly interact with one another. For instance, increased radiation (mainly thermal infrared) increases temperature, reduces humidity, consequently increases transpiration, and affects CO2 exchange as well as other reaction rates. Computational fluid dynamics (CFD) is a numerical tool with a solid physical basis which allows, through the construction of a computational model, to simulate the fluid flow environment. Heating, ventilation, and condensation have been analyzed in the greenhouse environment with CFD techniques. The current challenge is the interaction of these processes and their impact on the production system. The present work summarizes some CFD investigations carried out in this topic, in order to analyze the processes of heat and mass transfer in a greenhouse for agronomic purposes.",book:{id:"7661",slug:"heat-and-mass-transfer-advances-in-science-and-technology-applications",title:"Heat and Mass Transfer",fullTitle:"Heat and Mass Transfer - Advances in Science and Technology Applications"},signatures:"Cruz Ernesto Aguilar Rodriguez and Jorge Flores Velazquez",authors:[{id:"173578",title:"Dr.",name:"Jorge",middleName:null,surname:"Flores-Velazquez",slug:"jorge-flores-velazquez",fullName:"Jorge Flores-Velazquez"}]},{id:"66158",doi:"10.5772/intechopen.84706",title:"Numerical Solution to Two-Dimensional Freezing and Subsequent Defrosting of Logs",slug:"numerical-solution-to-two-dimensional-freezing-and-subsequent-defrosting-of-logs",totalDownloads:620,totalCrossrefCites:3,totalDimensionsCites:3,abstract:"Two-dimensional mutually connected mathematical models have been created, solved, and verified for the transient non-linear heat conduction in logs during their freezing and subsequent defrosting. The models reflect the influence of the internal sources of latent heat of both the free and bound water on the logs’ freezing process and also the impact of the temperature on the fiber saturation point of wood species, with whose participation the current values of the thermo-physical characteristics in each separate volume point of the subjected to freezing and subsequent defrosting logs are computed. The chapter presents solutions of the models with explicit form of the finite-difference method and their validation towards own experimental studies. Results from experimental and simulative investigation of 2D non-stationary temperature distribution in the longitudinal section of beech and pine logs with a diameter of 0.24 m and length of 0.48 m during their many hours freezing in a freezer and subsequent defrosting at room temperature are presented, visualized, and analyzed.",book:{id:"7661",slug:"heat-and-mass-transfer-advances-in-science-and-technology-applications",title:"Heat and Mass Transfer",fullTitle:"Heat and Mass Transfer - Advances in Science and Technology Applications"},signatures:"Nencho Deliiski and Natalia Tumbarkova",authors:[{id:"43040",title:"Prof.",name:"Nencho",middleName:"Stanev",surname:"Deliiski",slug:"nencho-deliiski",fullName:"Nencho Deliiski"},{id:"284649",title:"Dr.",name:"Natalia",middleName:"Yordanova",surname:"Tumbarkova",slug:"natalia-tumbarkova",fullName:"Natalia Tumbarkova"}]},{id:"67626",doi:"10.5772/intechopen.86738",title:"The Boundary Element Method for Fluctuating Active Colloids",slug:"the-boundary-element-method-for-fluctuating-active-colloids",totalDownloads:920,totalCrossrefCites:0,totalDimensionsCites:2,abstract:"The boundary element method (BEM) is a computational method particularly suited to solution of linear partial differential equations (PDEs), including the Laplace and Stokes equations, in complex geometries. The PDEs are formulated as boundary integral equations over bounding surfaces, which can be discretized for numerical solution. This manuscript reviews application of the BEM for simulation of the dynamics of “active” colloids that can self-propel through liquid solution. We introduce basic concepts and model equations for both catalytically active colloids and the “squirmer” model of a ciliated biological microswimmer. We review the foundations of the BEM for both the Laplace and Stokes equations, including the application to confined geometries, and the extension of the method to include thermal fluctuations of the colloid. Finally, we discuss recent and potential applications to research problems concerning active colloids. The aim of this review is to facilitate development and adoption of boundary element models that capture the interplay of deterministic and stochastic effects in the dynamics of active colloids.",book:{id:"8416",slug:"non-equilibrium-particle-dynamics",title:"Non-Equilibrium Particle Dynamics",fullTitle:"Non-Equilibrium Particle Dynamics"},signatures:"William E. Uspal",authors:[{id:"279308",title:"Prof.",name:"William",middleName:null,surname:"Uspal",slug:"william-uspal",fullName:"William Uspal"}]},{id:"66487",doi:"10.5772/intechopen.85735",title:"Mean Aspects Controlling Supercritical CO2 Precipitation Processes",slug:"mean-aspects-controlling-supercritical-co-sub-2-sub-precipitation-processes",totalDownloads:736,totalCrossrefCites:1,totalDimensionsCites:2,abstract:"The use of supercritical CO2 is an excellent alternative in extraction, particle precipitation, impregnation and reaction processes due to its special properties. Solubility of the compound in supercritical CO2 drives the precipitation process in different ways. In supercritical antisolvent process, mass and heat transfers, phase equilibria, nucleation, and growth of the compound to be precipitated are the main phenomena that should be taken into account. Mass transfer conditions the morphology and particle size of the final product. This transfer could be tuned altering operating conditions. Heat transfer in non-isothermal process influences on mixing step the size of generated microparticles. In rapid expansion of supercritical solution, phenomena as the phase change from supercritical to a CO2 gas flow, rapid mass transfer and crystallization of the compound, and expansion jet define the morphology and size of the final product. These phenomena a priori could be modulated tuning a large number of operating parameters through the experiments, but the correlations and modeling of these processes are necessary to clarify the relative importance of each one. Moreover, particle agglomeration in the expansion jet and CO2 condensation are determinant phenomena which should be avoided in order to conserve fine particles in the final product.",book:{id:"7661",slug:"heat-and-mass-transfer-advances-in-science-and-technology-applications",title:"Heat and Mass Transfer",fullTitle:"Heat and Mass Transfer - Advances in Science and Technology Applications"},signatures:"Antonio Montes, Clara Pereyra and Enrique J. Martínez de la Ossa",authors:[{id:"55991",title:"Mr.",name:"Antonio",middleName:null,surname:"Montes",slug:"antonio-montes",fullName:"Antonio Montes"},{id:"55992",title:"Dr.",name:"Clara",middleName:null,surname:"Pereyra",slug:"clara-pereyra",fullName:"Clara Pereyra"},{id:"55993",title:"Dr.",name:"Enrique",middleName:null,surname:"Martinez De La Ossa",slug:"enrique-martinez-de-la-ossa",fullName:"Enrique Martinez De La Ossa"}]},{id:"66317",doi:"10.5772/intechopen.85254",title:"Review Heat Transfer of Non-Newtonian Fluids in Agitated Tanks",slug:"review-heat-transfer-of-non-newtonian-fluids-in-agitated-tanks",totalDownloads:1001,totalCrossrefCites:1,totalDimensionsCites:1,abstract:"The heating and cooling of non-Newtonian liquids in tanks with mechanical impellers are operations commonly employed as chemical reactors, heat exchangers, distillers, extractors, thinners and decanters. In particular, the design of heat exchangers (jackets, helical coils, spiral coils and vertical tubular baffles) in tanks requires the prior knowledge of the rheology of the liquid for the calculation of the convection coefficients and the Reynolds number, in order to obtain the area thermal exchange. This chapter aimed to present the basic concepts of tanks with agitation, non-Newtonian liquids, hydrodynamics, heat transfer and, finally, with a practical design example for engineers and undergraduate students.",book:{id:"7661",slug:"heat-and-mass-transfer-advances-in-science-and-technology-applications",title:"Heat and Mass Transfer",fullTitle:"Heat and Mass Transfer - Advances in Science and Technology Applications"},signatures:"Vitor da Silva Rosa and Deovaldo de Moraes Júnior",authors:[{id:"187128",title:"Ph.D.",name:"Vitor",middleName:null,surname:"Rosa",slug:"vitor-rosa",fullName:"Vitor Rosa"},{id:"188792",title:"Dr.",name:"Deovaldo",middleName:null,surname:"Moraes Júnior",slug:"deovaldo-moraes-junior",fullName:"Deovaldo Moraes Júnior"}]}],mostDownloadedChaptersLast30Days:[{id:"66878",title:"Design of Industrial Falling Film Evaporators",slug:"design-of-industrial-falling-film-evaporators",totalDownloads:1753,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"The high performance evaporators are important for process industries such as food, desalination and refineries. The falling film evaporators have many advantages over flooded and vertical tubes that make them best candidate for processes industries application. The heat transfer area is the key parameter in designing of an evaporator and many correlations are available to estimate the size of tube bundle. Unfortunately, most of the correlation is available only for pure water and above 322 K saturation temperatures. Out of these conditions, the areas are designed by the extrapolation of existing correlations. We demonstrated that the actual heat transfer values are 2–3-fold higher at lower temperature and hence simple extrapolated estimation leads to inefficient and high capital cost design. We proposed an accurate heat transfer correlation for falling film evaporators that can capture both, low temperature evaporation and salt concentration effectively. It is also embedded with unique bubble-assisted evaporation parameter that can be only observed at low temperature and it enhances the heat transfer. The proposed correlation is applicable from 280 to 305 K saturation temperatures and feed water concentration ranges from 35,000 to 95,000 ppm. The uncertainty of measured data is less than 5% and RMS of regressed data is 3.5%. In this chapter, first part summarized the all available correlations and their limitations. In second part, falling film evaporation heat transfer coefficient (FFHTC) is proposed and model is developed. In the last part, experimentation is conducted and FFHTC developed and compared with conventional correlations.",book:{id:"7661",slug:"heat-and-mass-transfer-advances-in-science-and-technology-applications",title:"Heat and Mass Transfer",fullTitle:"Heat and Mass Transfer - Advances in Science and Technology Applications"},signatures:"Muhammad Wakil Shahzad, Muhammad Burhan and Kim Choon Ng",authors:[{id:"174208",title:"Dr.",name:"Muhammad Wakil",middleName:null,surname:"Shahzad",slug:"muhammad-wakil-shahzad",fullName:"Muhammad Wakil Shahzad"},{id:"249811",title:"Dr.",name:"Muhammad",middleName:null,surname:"Burhan",slug:"muhammad-burhan",fullName:"Muhammad Burhan"},{id:"254696",title:"Prof.",name:"Kim Choon",middleName:null,surname:"Ng",slug:"kim-choon-ng",fullName:"Kim Choon Ng"}]},{id:"66102",title:"Heat and Mass Transfer of Additive Manufacturing Processes for Metals",slug:"heat-and-mass-transfer-of-additive-manufacturing-processes-for-metals",totalDownloads:1302,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"Additive manufacturing (AM), a method in which a part is fabricated layer by layer from a digital design package, provides the potential to produce complex components at reduced cost and time. Many techniques (using many different names) have been developed to accomplish this via melting or solid-state joining. However, to date, only a handful can be used to produce metallic parts that fulfill the requirements of industrial applications. The thermal physics and weld pool behaviors in metal AM process have decisive influence on the deposition quality, the microstructure and service performance of the depositions. Accurate analysis and calculation of thermal processes and weld pool behaviors are of great significance to the metallurgy analysis, stress and deformation analysis, process control and process optimization etc. Numerical modeling is also a necessary way to turn welding from qualitative description and experience-based art into quantitative analysis- and science-based engineering branch. In this chapter, two techniques for producing metal parts are explored, with a focus on the thermal science of metal AM: fluid flow and heat transfer. Selective laser melting (SLM) is the one that is most widely used because it typically has the best resolution. Another is named metal fused-coated additive manufacturing (MFCAM) that is cost competitive and efficient in producing large and middle-complex components in aerospace applications.",book:{id:"7661",slug:"heat-and-mass-transfer-advances-in-science-and-technology-applications",title:"Heat and Mass Transfer",fullTitle:"Heat and Mass Transfer - Advances in Science and Technology Applications"},signatures:"Zhengying Wei and Jun Du",authors:[{id:"47614",title:"Prof.",name:"Zhengying",middleName:null,surname:"Wei",slug:"zhengying-wei",fullName:"Zhengying Wei"},{id:"282052",title:"Dr.",name:"Jun",middleName:null,surname:"Du",slug:"jun-du",fullName:"Jun Du"}]},{id:"66563",title:"Heat and Mass Transfer in Outward Convex Corrugated Tube Heat Exchangers",slug:"heat-and-mass-transfer-in-outward-convex-corrugated-tube-heat-exchangers",totalDownloads:1037,totalCrossrefCites:0,totalDimensionsCites:1,abstract:"Heat and mass transfer in outward convex corrugated tube heat exchangers is of significant importance for the optimization, fabrication, and application of outward convex corrugated tube heat exchangers. This chapter gives a deep investigation of the heat and mass transfer in outward convex corrugated tube heat exchangers. Based on the experimental setup developed, the performances of a novel outward convex corrugated tube heat exchanger are presented. Simulation methods are then used to detail the heat and mass transfer at tube side and shell side of the outward convex corrugated tube heat exchanger, and these include the flow structure, temperature distribution, and turbulence kinetic energy. Heat and mass transfer enhancements of the outward convex corrugated tube heat exchanger are also studied, and they are from tube side, shell side, and overall system aspects. Finally, multi-objective optimization of the outward convex corrugated tube heat exchanger is conducted to obtain the optimal performances through using Response Surface Methodology (RSM) and Non-dominated Sorting Genetic Algorithm (NSGA-II). Main conclusions and future outlook are then briefly stated and summarized. We firmly believe that the contents presented in this chapter can not only enrich the knowledge of heat exchangers but also develop methods for studying heat exchangers.",book:{id:"7661",slug:"heat-and-mass-transfer-advances-in-science-and-technology-applications",title:"Heat and Mass Transfer",fullTitle:"Heat and Mass Transfer - Advances in Science and Technology Applications"},signatures:"Huaizhi Han, Bingxi Li, Yaning Zhang, Quan Zhu and Ruitian Yu",authors:[{id:"23828",title:"Dr.",name:"Quan",middleName:null,surname:"Zhu",slug:"quan-zhu",fullName:"Quan Zhu"},{id:"148369",title:"Prof.",name:"Bingxi",middleName:null,surname:"Li",slug:"bingxi-li",fullName:"Bingxi Li"},{id:"196928",title:"Dr.",name:"Yaning",middleName:null,surname:"Zhang",slug:"yaning-zhang",fullName:"Yaning Zhang"},{id:"281875",title:"Prof.",name:"Huaizhi",middleName:null,surname:"Han",slug:"huaizhi-han",fullName:"Huaizhi Han"},{id:"282268",title:"Mr.",name:"Ruitian",middleName:null,surname:"Yu",slug:"ruitian-yu",fullName:"Ruitian Yu"}]},{id:"66317",title:"Review Heat Transfer of Non-Newtonian Fluids in Agitated Tanks",slug:"review-heat-transfer-of-non-newtonian-fluids-in-agitated-tanks",totalDownloads:1001,totalCrossrefCites:1,totalDimensionsCites:1,abstract:"The heating and cooling of non-Newtonian liquids in tanks with mechanical impellers are operations commonly employed as chemical reactors, heat exchangers, distillers, extractors, thinners and decanters. In particular, the design of heat exchangers (jackets, helical coils, spiral coils and vertical tubular baffles) in tanks requires the prior knowledge of the rheology of the liquid for the calculation of the convection coefficients and the Reynolds number, in order to obtain the area thermal exchange. This chapter aimed to present the basic concepts of tanks with agitation, non-Newtonian liquids, hydrodynamics, heat transfer and, finally, with a practical design example for engineers and undergraduate students.",book:{id:"7661",slug:"heat-and-mass-transfer-advances-in-science-and-technology-applications",title:"Heat and Mass Transfer",fullTitle:"Heat and Mass Transfer - Advances in Science and Technology Applications"},signatures:"Vitor da Silva Rosa and Deovaldo de Moraes Júnior",authors:[{id:"187128",title:"Ph.D.",name:"Vitor",middleName:null,surname:"Rosa",slug:"vitor-rosa",fullName:"Vitor Rosa"},{id:"188792",title:"Dr.",name:"Deovaldo",middleName:null,surname:"Moraes Júnior",slug:"deovaldo-moraes-junior",fullName:"Deovaldo Moraes Júnior"}]},{id:"65692",title:"Advances in Concentrated Solar Power: A Perspective of Heat Transfer",slug:"advances-in-concentrated-solar-power-a-perspective-of-heat-transfer",totalDownloads:1114,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"Solar energy has the potential to reduce the dependence on the dwindling supply of fossil fuels through concentrated solar power (CSP) technology. CSP plants utilize solar thermal energy to produce electrical energy based on different thermodynamic power cycles. Solar collectors, reflectors, receivers, thermal fluid, and turbines are the main components of each CSP plant and involve intensive heat transfer at all stages. This chapter illustrates the thermal characteristics of the main components used in CSP technology. In addition, the solar thermal fluid characteristics and its stable operational ranges are discussed in this chapter. Heat capacity, vapor pressure, volume expansion, density and viscosity of the thermal fluid should not differ significantly at different temperatures during various operation stages because these variations can cause failure in the system, which is designed at the fixed material properties. Currently, CSP technology is associated with a higher cost compared to the electricity generated through gas power plants. Many efforts are made to search for sustainable and inexpensive materials to minimize the cost of CSP. One critical issue faced by CSP technology is the intermittent nature of the sun. Modern CSP plants integrate thermal energy storage (TES) unit to smoothen the power production or to shift the production from peak sunshine hours to peak demand hours.",book:{id:"7661",slug:"heat-and-mass-transfer-advances-in-science-and-technology-applications",title:"Heat and Mass Transfer",fullTitle:"Heat and Mass Transfer - Advances in Science and Technology Applications"},signatures:"Fadi Alnaimat and Yasir Rashid",authors:[{id:"151722",title:"Dr.",name:"Fadi",middleName:null,surname:"Alnaimat",slug:"fadi-alnaimat",fullName:"Fadi Alnaimat"},{id:"291252",title:"Mr.",name:"Yasir",middleName:null,surname:"Rashid",slug:"yasir-rashid",fullName:"Yasir Rashid"}]}],onlineFirstChaptersFilter:{topicId:"954",limit:6,offset:0},onlineFirstChaptersCollection:[],onlineFirstChaptersTotal:0},preDownload:{success:null,errors:{}},subscriptionForm:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[],offset:8,limit:8,total:0},allSeries:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:8,numberOfPublishedChapters:87,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:98,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:27,numberOfPublishedChapters:286,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:9,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:11,numberOfPublishedChapters:139,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:8,numberOfPublishedChapters:129,numberOfOpenTopics:0,numberOfUpcomingTopics:2,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!1},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:106,numberOfOpenTopics:3,numberOfUpcomingTopics:1,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:9,numberOfPublishedChapters:101,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:11,numberOfOpenTopics:2,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:0,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!1},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:0,numberOfPublishedChapters:9,numberOfOpenTopics:4,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],testimonialsList:[{id:"13",text:"The collaboration with and support of the technical staff of IntechOpen is fantastic. The whole process of submitting an article and editing of the submitted article goes extremely smooth and fast, the number of reads and downloads of chapters is high, and the contributions are also frequently cited.",author:{id:"55578",name:"Antonio",surname:"Jurado-Navas",institutionString:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRisIQAS/Profile_Picture_1626166543950",slug:"antonio-jurado-navas",institution:{id:"720",name:"University of Malaga",country:{id:null,name:"Spain"}}}},{id:"6",text:"It is great to work with the IntechOpen to produce a worthwhile collection of research that also becomes a great educational resource and guide for future research endeavors.",author:{id:"259298",name:"Edward",surname:"Narayan",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259298/images/system/259298.jpeg",slug:"edward-narayan",institution:{id:"3",name:"University of Queensland",country:{id:null,name:"Australia"}}}}]},series:{item:{id:"24",title:"Sustainable Development",doi:"10.5772/intechopen.100361",issn:null,scope:"
\r\n\tTransforming our World: the 2030 Agenda for Sustainable Development endorsed by United Nations and 193 Member States, came into effect on Jan 1, 2016, to guide decision making and actions to the year 2030 and beyond. Central to this Agenda are 17 Goals, 169 associated targets and over 230 indicators that are reviewed annually. The vision envisaged in the implementation of the SDGs is centered on the five Ps: People, Planet, Prosperity, Peace and Partnership. This call for renewed focused efforts ensure we have a safe and healthy planet for current and future generations.
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\r\n\tThis Series focuses on covering research and applied research involving the five Ps through the following topics:
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\r\n\t1. Sustainable Economy and Fair Society that relates to SDG 1 on No Poverty, SDG 2 on Zero Hunger, SDG 8 on Decent Work and Economic Growth, SDG 10 on Reduced Inequalities, SDG 12 on Responsible Consumption and Production, and SDG 17 Partnership for the Goals
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\r\n\t2. Health and Wellbeing focusing on SDG 3 on Good Health and Wellbeing and SDG 6 on Clean Water and Sanitation
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\r\n\t3. Inclusivity and Social Equality involving SDG 4 on Quality Education, SDG 5 on Gender Equality, and SDG 16 on Peace, Justice and Strong Institutions
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\r\n\t4. Climate Change and Environmental Sustainability comprising SDG 13 on Climate Action, SDG 14 on Life Below Water, and SDG 15 on Life on Land
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\r\n\t5. Urban Planning and Environmental Management embracing SDG 7 on Affordable Clean Energy, SDG 9 on Industry, Innovation and Infrastructure, and SDG 11 on Sustainable Cities and Communities.
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\r\n\tThe series also seeks to support the use of cross cutting SDGs, as many of the goals listed above, targets and indicators are all interconnected to impact our lives and the decisions we make on a daily basis, making them impossible to tie to a single topic.
",coverUrl:"https://cdn.intechopen.com/series/covers/24.jpg",latestPublicationDate:"April 24th, 2022",hasOnlineFirst:!0,numberOfPublishedBooks:0,editor:{id:"262440",title:"Prof.",name:"Usha",middleName:null,surname:"Iyer-Raniga",slug:"usha-iyer-raniga",fullName:"Usha Iyer-Raniga",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRYSXQA4/Profile_Picture_2022-02-28T13:55:36.jpeg",biography:"Usha Iyer-Raniga is a professor in the School of Property and Construction Management at RMIT University. Usha co-leads the One Planet Network’s Sustainable Buildings and Construction Programme (SBC), a United Nations 10 Year Framework of Programmes on Sustainable Consumption and Production (UN 10FYP SCP) aligned with Sustainable Development Goal 12. The work also directly impacts SDG 11 on Sustainable Cities and Communities. She completed her undergraduate degree as an architect before obtaining her Masters degree from Canada and her Doctorate in Australia. Usha has been a keynote speaker as well as an invited speaker at national and international conferences, seminars and workshops. Her teaching experience includes teaching in Asian countries. She has advised Austrade, APEC, national, state and local governments. She serves as a reviewer and a member of the scientific committee for national and international refereed journals and refereed conferences. She is on the editorial board for refereed journals and has worked on Special Issues. Usha has served and continues to serve on the Boards of several not-for-profit organisations and she has also served as panel judge for a number of awards including the Premiers Sustainability Award in Victoria and the International Green Gown Awards. Usha has published over 100 publications, including research and consulting reports. Her publications cover a wide range of scientific and technical research publications that include edited books, book chapters, refereed journals, refereed conference papers and reports for local, state and federal government clients. She has also produced podcasts for various organisations and participated in media interviews. She has received state, national and international funding worth over USD $25 million. Usha has been awarded the Quarterly Franklin Membership by London Journals Press (UK). Her biography has been included in the Marquis Who's Who in the World® 2018, 2016 (33rd Edition), along with approximately 55,000 of the most accomplished men and women from around the world, including luminaries as U.N. Secretary-General Ban Ki-moon. In 2017, Usha was awarded the Marquis Who’s Who Lifetime Achiever Award.",institutionString:null,institution:{name:"RMIT University",institutionURL:null,country:{name:"Australia"}}},editorTwo:null,editorThree:null},subseries:{paginationCount:4,paginationItems:[{id:"14",title:"Cell and Molecular Biology",coverUrl:"https://cdn.intechopen.com/series_topics/covers/14.jpg",isOpenForSubmission:!0,editor:{id:"165627",title:"Dr.",name:"Rosa María",middleName:null,surname:"Martínez-Espinosa",slug:"rosa-maria-martinez-espinosa",fullName:"Rosa María Martínez-Espinosa",profilePictureURL:"https://mts.intechopen.com/storage/users/165627/images/system/165627.jpeg",biography:"Dr. Rosa María Martínez-Espinosa has been a Spanish Full Professor since 2020 (Biochemistry and Molecular Biology) and is currently Vice-President of International Relations and Cooperation development and leader of the research group 'Applied Biochemistry” (University of Alicante, Spain). Other positions she has held at the university include Vice-Dean of Master Programs, Vice-Dean of the Degree in Biology and Vice-Dean for Mobility and Enterprise and Engagement at the Faculty of Science (University of Alicante). She received her Bachelor in Biology in 1998 (University of Alicante) and her PhD in 2003 (Biochemistry, University of Alicante). She undertook post-doctoral research at the University of East Anglia (Norwich, U.K. 2004-2005; 2007-2008).\nHer multidisciplinary research focuses on investigating archaea and their potential applications in biotechnology. She has an H-index of 21. She has authored one patent and has published more than 70 indexed papers and around 60 book chapters.\nShe has contributed to more than 150 national and international meetings during the last 15 years. Her research interests include archaea metabolism, enzymes purification and characterization, gene regulation, carotenoids and bioplastics production, antioxidant\ncompounds, waste water treatments, and brines bioremediation.\nRosa María’s other roles include editorial board member for several journals related\nto biochemistry, reviewer for more than 60 journals (biochemistry, molecular biology, biotechnology, chemistry and microbiology) and president of several organizing committees in international meetings related to the N-cycle or respiratory processes.",institutionString:null,institution:{name:"University of Alicante",institutionURL:null,country:{name:"Spain"}}},editorTwo:null,editorThree:null},{id:"15",title:"Chemical Biology",coverUrl:"https://cdn.intechopen.com/series_topics/covers/15.jpg",isOpenForSubmission:!0,editor:{id:"441442",title:"Dr.",name:"Şükrü",middleName:null,surname:"Beydemir",slug:"sukru-beydemir",fullName:"Şükrü Beydemir",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00003GsUoIQAV/Profile_Picture_1634557147521",biography:"Dr. Şükrü Beydemir obtained a BSc in Chemistry in 1995 from Yüzüncü Yıl University, MSc in Biochemistry in 1998, and PhD in Biochemistry in 2002 from Atatürk University, Turkey. He performed post-doctoral studies at Max-Planck Institute, Germany, and University of Florence, Italy in addition to making several scientific visits abroad. He currently works as a Full Professor of Biochemistry in the Faculty of Pharmacy, Anadolu University, Turkey. Dr. Beydemir has published over a hundred scientific papers spanning protein biochemistry, enzymology and medicinal chemistry, reviews, book chapters and presented several conferences to scientists worldwide. He has received numerous publication awards from various international scientific councils. He serves in the Editorial Board of several international journals. Dr. Beydemir is also Rector of Bilecik Şeyh Edebali University, Turkey.",institutionString:null,institution:{name:"Anadolu University",institutionURL:null,country:{name:"Turkey"}}},editorTwo:{id:"13652",title:"Prof.",name:"Deniz",middleName:null,surname:"Ekinci",slug:"deniz-ekinci",fullName:"Deniz Ekinci",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYLT1QAO/Profile_Picture_1634557223079",biography:"Dr. Deniz Ekinci obtained a BSc in Chemistry in 2004, MSc in Biochemistry in 2006, and PhD in Biochemistry in 2009 from Atatürk University, Turkey. He studied at Stetson University, USA, in 2007-2008 and at the Max Planck Institute of Molecular Cell Biology and Genetics, Germany, in 2009-2010. Dr. Ekinci currently works as a Full Professor of Biochemistry in the Faculty of Agriculture and is the Head of the Enzyme and Microbial Biotechnology Division, Ondokuz Mayıs University, Turkey. He is a member of the Turkish Biochemical Society, American Chemical Society, and German Genetics society. Dr. Ekinci published around ninety scientific papers, reviews and book chapters, and presented several conferences to scientists. He has received numerous publication awards from several scientific councils. Dr. Ekinci serves as the Editor in Chief of four international books and is involved in the Editorial Board of several international journals.",institutionString:null,institution:{name:"Ondokuz Mayıs University",institutionURL:null,country:{name:"Turkey"}}},editorThree:null},{id:"17",title:"Metabolism",coverUrl:"https://cdn.intechopen.com/series_topics/covers/17.jpg",isOpenForSubmission:!0,editor:{id:"138626",title:"Dr.",name:"Yannis",middleName:null,surname:"Karamanos",slug:"yannis-karamanos",fullName:"Yannis Karamanos",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002g6Jv2QAE/Profile_Picture_1629356660984",biography:"Yannis Karamanos, born in Greece in 1953, completed his pre-graduate studies at the Université Pierre et Marie Curie, Paris, then his Masters and Doctoral degree at the Université de Lille (1983). He was associate professor at the University of Limoges (1987) before becoming full professor of biochemistry at the Université d’Artois (1996). He worked on the structure-function relationships of glycoconjugates and his main project was the investigations on the biological roles of the de-N-glycosylation enzymes (Endo-N-acetyl-β-D-glucosaminidase and peptide-N4-(N-acetyl-β-glucosaminyl) asparagine amidase). From 2002 he contributes to the understanding of the Blood-brain barrier functioning using proteomics approaches. He has published more than 70 papers. His teaching areas are energy metabolism and regulation, integration and organ specialization and metabolic adaptation.",institutionString:null,institution:{name:"Artois University",institutionURL:null,country:{name:"France"}}},editorTwo:null,editorThree:null},{id:"18",title:"Proteomics",coverUrl:"https://cdn.intechopen.com/series_topics/covers/18.jpg",isOpenForSubmission:!0,editor:{id:"200689",title:"Prof.",name:"Paolo",middleName:null,surname:"Iadarola",slug:"paolo-iadarola",fullName:"Paolo Iadarola",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSCl8QAG/Profile_Picture_1623568118342",biography:"Paolo Iadarola graduated with a degree in Chemistry from the University of Pavia (Italy) in July 1972. He then worked as an Assistant Professor at the Faculty of Science of the same University until 1984. In 1985, Prof. Iadarola became Associate Professor at the Department of Biology and Biotechnologies of the University of Pavia and retired in October 2017. Since then, he has been working as an Adjunct Professor in the same Department at the University of Pavia. His research activity during the first years was primarily focused on the purification and structural characterization of enzymes from animal and plant sources. During this period, Prof. Iadarola familiarized himself with the conventional techniques used in column chromatography, spectrophotometry, manual Edman degradation, and electrophoresis). Since 1995, he has been working on: i) the determination in biological fluids (serum, urine, bronchoalveolar lavage, sputum) of proteolytic activities involved in the degradation processes of connective tissue matrix, and ii) on the identification of biological markers of lung diseases. In this context, he has developed and validated new methodologies (e.g., Capillary Electrophoresis coupled to Laser-Induced Fluorescence, CE-LIF) whose application enabled him to determine both the amounts of biochemical markers (Desmosines) in urine/serum of patients affected by Chronic Obstructive Pulmonary Disease (COPD) and the activity of proteolytic enzymes (Human Neutrophil Elastase, Cathepsin G, Pseudomonas aeruginosa elastase) in sputa of these patients. More recently, Prof. Iadarola was involved in developing techniques such as two-dimensional electrophoresis coupled to liquid chromatography/mass spectrometry (2DE-LC/MS) for the proteomic analysis of biological fluids aimed at the identification of potential biomarkers of different lung diseases. He is the author of about 150 publications (According to Scopus: H-Index: 23; Total citations: 1568- According to WOS: H-Index: 20; Total Citations: 1296) of peer-reviewed international journals. He is a Consultant Reviewer for several journals, including the Journal of Chromatography A, Journal of Chromatography B, Plos ONE, Proteomes, International Journal of Molecular Science, Biotech, Electrophoresis, and others. He is also Associate Editor of Biotech.",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorTwo:{id:"201414",title:"Dr.",name:"Simona",middleName:null,surname:"Viglio",slug:"simona-viglio",fullName:"Simona Viglio",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRKDHQA4/Profile_Picture_1630402531487",biography:"Simona Viglio is an Associate Professor of Biochemistry at the Department of Molecular Medicine at the University of Pavia. She has been working since 1995 on the determination of proteolytic enzymes involved in the degradation process of connective tissue matrix and on the identification of biological markers of lung diseases. She gained considerable experience in developing and validating new methodologies whose applications allowed her to determine both the amount of biomarkers (Desmosine and Isodesmosine) in the urine of patients affected by COPD, and the activity of proteolytic enzymes (HNE, Cathepsin G, Pseudomonas aeruginosa elastase) in the sputa of these patients. Simona Viglio was also involved in research dealing with the supplementation of amino acids in patients with brain injury and chronic heart failure. She is presently engaged in the development of 2-DE and LC-MS techniques for the study of proteomics in biological fluids. The aim of this research is the identification of potential biomarkers of lung diseases. She is an author of about 90 publications (According to Scopus: H-Index: 23; According to WOS: H-Index: 20) on peer-reviewed journals, a member of the “Società Italiana di Biochimica e Biologia Molecolare,“ and a Consultant Reviewer for International Journal of Molecular Science, Journal of Chromatography A, COPD, Plos ONE and Nutritional Neuroscience.",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorThree:null}]},overviewPageOFChapters:{paginationCount:49,paginationItems:[{id:"80495",title:"Iron in Cell Metabolism and Disease",doi:"10.5772/intechopen.101908",signatures:"Eeka Prabhakar",slug:"iron-in-cell-metabolism-and-disease",totalDownloads:0,totalCrossrefCites:null,totalDimensionsCites:null,authors:null,book:{title:"Iron Metabolism - Iron a Double‐Edged Sword",coverURL:"https://cdn.intechopen.com/books/images_new/10842.jpg",subseries:{id:"17",title:"Metabolism"}}},{id:"81799",title:"Cross Talk of Purinergic and Immune Signaling: Implication in Inflammatory and Pathogenic Diseases",doi:"10.5772/intechopen.104978",signatures:"Richa Rai",slug:"cross-talk-of-purinergic-and-immune-signaling-implication-in-inflammatory-and-pathogenic-diseases",totalDownloads:7,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Purinergic System",coverURL:"https://cdn.intechopen.com/books/images_new/10801.jpg",subseries:{id:"17",title:"Metabolism"}}},{id:"81764",title:"Involvement of the Purinergic System in Cell Death in Models of Retinopathies",doi:"10.5772/intechopen.103935",signatures:"Douglas Penaforte Cruz, Marinna Garcia Repossi and Lucianne Fragel Madeira",slug:"involvement-of-the-purinergic-system-in-cell-death-in-models-of-retinopathies",totalDownloads:4,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Purinergic System",coverURL:"https://cdn.intechopen.com/books/images_new/10801.jpg",subseries:{id:"17",title:"Metabolism"}}},{id:"81756",title:"Alteration of Cytokines Level and Oxidative Stress Parameters in COVID-19",doi:"10.5772/intechopen.104950",signatures:"Marija Petrusevska, Emilija Atanasovska, Dragica Zendelovska, Aleksandar Eftimov and Katerina Spasovska",slug:"alteration-of-cytokines-level-and-oxidative-stress-parameters-in-covid-19",totalDownloads:8,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Chemokines Updates",coverURL:"https://cdn.intechopen.com/books/images_new/11672.jpg",subseries:{id:"18",title:"Proteomics"}}}]},overviewPagePublishedBooks:{paginationCount:27,paginationItems:[{type:"book",id:"7006",title:"Biochemistry and Health Benefits of Fatty Acids",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7006.jpg",slug:"biochemistry-and-health-benefits-of-fatty-acids",publishedDate:"December 19th 2018",editedByType:"Edited by",bookSignature:"Viduranga Waisundara",hash:"c93a00abd68b5eba67e5e719f67fd20b",volumeInSeries:1,fullTitle:"Biochemistry and Health Benefits of Fatty Acids",editors:[{id:"194281",title:"Dr.",name:"Viduranga Y.",middleName:null,surname:"Waisundara",slug:"viduranga-y.-waisundara",fullName:"Viduranga Y. Waisundara",profilePictureURL:"https://mts.intechopen.com/storage/users/194281/images/system/194281.jpg",biography:"Dr. Viduranga Waisundara obtained her Ph.D. in Food Science and Technology from the Department of Chemistry, National University of Singapore, in 2010. She was a lecturer at Temasek Polytechnic, Singapore from July 2009 to March 2013. She relocated to her motherland of Sri Lanka and spearheaded the Functional Food Product Development Project at the National Institute of Fundamental Studies from April 2013 to October 2016. She was a senior lecturer on a temporary basis at the Department of Food Technology, Faculty of Technology, Rajarata University of Sri Lanka. She is currently Deputy Principal of the Australian College of Business and Technology – Kandy Campus, Sri Lanka. 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The applications of this research cover many related fields, such as biotechnology and medicine, where, for example, Bioinformatics contributes to faster drug design, DNA analysis in forensics, and DNA sequence analysis in the field of personalized medicine. Personalized medicine is a type of medical care in which treatment is customized individually for each patient. Personalized medicine enables more effective therapy, reduces the costs of therapy and clinical trials, and also minimizes the risk of side effects. Nevertheless, advances in personalized medicine would not have been possible without bioinformatics, which can analyze the human genome and other vast amounts of biomedical data, especially in genetics. The rapid growth of information technology enabled the development of new tools to decode human genomes, large-scale studies of genetic variations and medical informatics. 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We encourage the submission of manuscripts that provide novel and mechanistic insights that report significant advances in the fields. Topics can include but are not limited to: Biotechnology such as biotechnological products and process engineering; Biotechnologically relevant enzymes and proteins; Bioenergy and biofuels; Applied genetics and molecular biotechnology; Genomics, transcriptomics, proteomics; Applied microbial and cell physiology; Environmental biotechnology; Methods and protocols. Moreover, topics in biosensor technology, like sensors that incorporate enzymes, antibodies, nucleic acids, whole cells, tissues and organelles, and other biological or biologically inspired components will be considered, and topics exploring transducers, including those based on electrochemical and optical piezoelectric, thermal, magnetic, and micromechanical elements. 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