Optimized dimensions of circular OCA employing square AMC.
\\n\\n
Released this past November, the list is based on data collected from the Web of Science and highlights some of the world’s most influential scientific minds by naming the researchers whose publications over the previous decade have included a high number of Highly Cited Papers placing them among the top 1% most-cited.
\\n\\nWe wish to congratulate all of the researchers named and especially our authors on this amazing accomplishment! We are happy and proud to share in their success!
Note: Edited in March 2021
\\n"}]',published:!0,mainMedia:{caption:"Highly Cited",originalUrl:"/media/original/117"}},components:[{type:"htmlEditorComponent",content:'IntechOpen is proud to announce that 191 of our authors have made the Clarivate™ Highly Cited Researchers List for 2020, ranking them among the top 1% most-cited.
\n\nThroughout the years, the list has named a total of 261 IntechOpen authors as Highly Cited. Of those researchers, 69 have been featured on the list multiple times.
\n\n\n\nReleased this past November, the list is based on data collected from the Web of Science and highlights some of the world’s most influential scientific minds by naming the researchers whose publications over the previous decade have included a high number of Highly Cited Papers placing them among the top 1% most-cited.
\n\nWe wish to congratulate all of the researchers named and especially our authors on this amazing accomplishment! We are happy and proud to share in their success!
Note: Edited in March 2021
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This wide-ranging bandwidth allows for high data rate transmission of several gigabit-per-second (Gbps) suppressing the current low-frequency systems below 10 GHz. This excessive data rate opens the door for many applications such as high-speed video and computer display streaming, Gbps networking, uncompressed high-definition media transfers, wireless personal area access, chip-to-chip communications, sensing applications, information showers, and virtually instantaneous admission to massive libraries of information. Moreover, an additional advantage of the 60-GHz carrier is the possibility of small-distance frequency reuse because of the high attenuation caused by oxygen molecules at the level of 10–15 dB/km. This frequency reuse attribute empowers the 60-GHz system to be an appropriate replacement for the contemporary short-range wireless communications systems. Additionally, the short free-space wavelength of 5 mm at 60 GHz enables small-size passive devices fabrication with integration capability into a chip. On-chip integration of passive devices leads to a wholly system-on-chip (SOC) realization. SOC is an individual and remarkable solution that can facilitate low-cost wireless communication devices. The SOC promotes the integration on the same chip of the antenna, front-end circuits, and back-end circuits. This SOC guarantees economical wireless communication devices thanks to the elimination of the costs associated with materials required for external antennas. Also, the antennas’ matching circuits will be dismissed given that the 50-Ω boundary is no longer obligatory. Finally, SOC will guarantee a one-step foundry fabrication of the entire wireless system [1–16].
\nThe cost-effective complementary-metal-oxide-semiconductor (CMOS) process, which is the mainstream digital circuits’ technology, guarantees further cost reduction of the wireless system. Even though the CMOS substrate causes degradation of the radiation performance of the on-chip antennas (OCAs) due to its low resistivity and high permittivity [4–7], that is, the CMOS substrate is not optimized for the antennas operation. Many design methodologies have been utilized [4–12] to permit the improvement of the CMOS OCAs’ performance. These OCAs’ enhancement approaches have two main categories: (1) post-processing techniques [8–12] and (2) electromagnetic (EM) shielding [13–16].
\nPost-processing methods are techniques that utilize additional fabrication steps to the standard CMOS process to allow changing the characteristics of the CMOS substrate [8–12]. Micro-machining [8, 9] and proton implantation [10, 11] are two conventional CMOS post-processing methods. On the one hand, in the micro-machining approach, the OCA performance is enhanced by selectively removing parts of the CMOS substrate that lie directly below the OCA. Thus, the loss source is eliminated [8]. Wang et al. [8] had realized a peak measured gain and efficiency of 8 dBi and 60% by employing the selective etching technique together with array antenna at 130-GHz-operating frequency. Another micro-machining tactic uses post-supportive micro-machined walls to isolate the OCA far apart from the CMOS substrate [9]; hence, the coupling between the OCA and the substrate reduces and its radiation performance is enhanced. Kim et al. [9] had achieved a peak simulated gain and efficiency of 9.9 dBi and 94%, respectively by using this post-supportive walls method with patch antenna array at 60-GHz-operating frequency.
\nOn the other hand, the proton implantation course implements high-energy ions into the CMOS substrate below the OCA such that the CMOS substrate’s resistivity below the OCA becomes very high, the corresponding losses are reduced, and the OCA’s performance is enhanced [10, 11]. In Ref. [10], proton implantation increased the CMOS substrate resistivity from [22] 10 Ω.cm to 0.1 MΩ.cm. In return, the transmission gain is enriched by 20 dB. In Ref. [11], a helium-3 ion irradiation process is applied to reduce the substrate losses of the OCA. Therefore, the radiation efficiency of the OCA is doubled, and a measured peak gain of -4.1 dBi is possible at 60 GHz. However the possibility of high performance using the post-processing techniques, these techniques have two major disadvantages: (1) the extra costs associated with them due to the additional fabrication steps and (2) the repeatability of the fabrication process [12].
\nAlternatively, the EM shielding uses the standard CMOS technology without any further processing. The EM shielding employs artificial magnetic conductors (AMCs) to enhance OCA radiation performance such as gain and radiation efficiency [12–16]. In Ref. [13], Chu et al. implemented a wide band patch OCA with two parasitic patches and used a snowflake AMC as a shield. However the wide bandwidth, this design had shown low gain and low efficiency of -2.2 dBi and 15%, respectively. Barakat et al. [14, 15] designed a triangular patch OCA over Jerusalem-Cross (JC) [14] and square [15] AMC. A methodology to enhance gain and efficiency while maintaining small area is also proposed [14, 15]. In this methodology, gain and efficiency have been enhanced by increasing the number of AMC cells in the E-plane direction and reducing the number of AMC cells in the H-plane direction. A simulated gain and efficiency of 0 dBi and 39%, respectively, were observed for JC-AMC [14] and 0.7 dBi and 47%, respectively, for square-AMC [15]. Bao et al. [16] has proposed a double-loop OCA with modified star AMC. The double-loop OCA originally has circular polarization. When using full AMC layer below the double loop, the axial ratio bandwidth is reduced due to the coupling between the OCA and the AMC cells. To overcome this problem, Bao et al. [16] proposed selectively removing some cells from the AMC plan to maintain a wide axial-ratio bandwidth while efficiency is enhanced. An AR bandwidth (AR <3) was possible from 57 to 67 GHz with a peak measured gain of -4.4 dBi [16]. The AMC-based OCAs still have poor measured performance when compared to the post-processed OCAs [8–16].
\nThis chapter presents the design, implementation, and measurements of the 60-GHz CMOS OCAs. We propose two innovative techniques to advance the CMOS OCAs’ performance. The first method uses electromagnetic shielding employing asymmetric AMC. The OCAs based on the asymmetric AMC is superior in the gain-to-active-area ratio when compared to the OCAs making use of the traditional symmetric AMC as will be detailed in Section 2. The second scheme is the distributed N-well method. In this distributed N-well approach, the semiconductor physics characteristics of the PN-junction (PNJ) are utilized to consent the increase of the effective resistance of the CMOS substrate, hence, reducing the resulting losses and the OCA’s performance enhances. This chapter describes the distributed N-well tactic and its application to OCA’s performance boosting in Section 3.
\nIn this section, we report the use of asymmetric AMC to enhance the performance of the OCA. First, in Section 2.1, we detail the background of the AMCs showing their importance in antenna engineering applications. Then, we discuss the development of the asymmetric AMC from the traditional symmetric AMC in Section 2.2. Furthermore, in Section 2.3, we manipulate the symmetric and the asymmetric AMC in the OCA’s characteristics progression, comparing the resulting performances. Then, we detail the layout and fabrication consideration, the measurements technique used, and the measured data of the OCA with asymmetric AMC in Section 2.4.
\nAn AMC layer consists of periodic metal patches over a dielectric substrate in one-, two-, or three-dimensional (3D) configurations. AMC surfaces have two important and exciting properties that do not occur naturally and benefit a variety of microwave circuit applications. These two AMC individualities are the high impedance and the in-phase reflection properties. First, an AMC surface acts as a high-impedance layer that is useful as an antenna ground plane regarding surface-wave suppression. AMC shields have very high-surface impedances within an explicitly narrow frequency band, where the tangential magnetic field intensity is small, even with a large electric field intensity along the surface [17, 18]. Second, an AMC has an unusual reflection phase (RP) features of 0° at its center frequency; hence, an antenna on AMC produces a smoother radiation profile than a similar antenna on a conventional metallic ground plane, with less power wasted in the backward direction. These AMC capabilities are useful to the diversity of antenna schemes, for example, patch antennas, that frequently suffer from the consequences of surface waves propagation. For phased arrays, the suppression of the surface waves can reduce the mutual coupling between the array elements; hence, it helps to eliminate the blind-scanning angles.
\nFurthermore, an AMC is particularly applicable to the field of portable hand-held communication devices, in which the interaction between the antenna and the user can have a significant impact on both the antenna’s performance and the user’s health. An AMC acting as a shield between the antenna and the user in portable communications equipment can lead to a higher antenna efficiency, a longer battery life, a lower specific absorption rate (SAR) of the human body, and a lighter device weight. Likewise, in the case of OCA, an AMC surface is placed between the antenna and the lossy CMOS substrate. Consequently, the AMC surface allows for better OCA’s efficiency [13–18]. The reflection phase is the ratio between the phase of the reflected electric field and the phase of the incident electric field at the reflecting surface. In practice, the AMC plane exhibits a reflection coefficient of +1 at its center frequency and thus the reflected wave can constructively enhance the total electromagnetic field with the incident wave together at a low profile. On the contrary, the conventional perfect electrical conductor (PEC) plan delivers a reflection coefficient of -1 and therefore the reflected wave will destructively cancel the incident signal for low-profile operation.
\nThe reflection phase on the AMC plane varies with the frequency continuously from -180° to 180° and become zero at the center-operating frequency. The operational band of an AMC layer is the range for which the reflection phase changes from +90° to -90°, as in this bandwidth, the reflection phase values would not cause destructive interference between the direct and the reflected waves. Following this definition of the reflection phase, the AMC percentage bandwidth (BWAMC) can be calculated as in Eq. (1) [13–18], where
Figure 1(a) shows two consecutive unit cells of the symmetric square AMC [15, 19]. We used the high-frequency-structure-simulator (HFSS) to optimize the reflection phase (RP) response of this AMC and for other simulations in this chapter. Figure 1(b) shows the simulation setup to determine the square AMC’s RP response. Perfect-E and perfect-H boundary conditions are used to realize the periodic boundary conditions (PBCs). Excitation port is a wave port. We embed the reflection coefficient (S11) in the surface of the AMC unit cell and compute the RP response as the angle of the embedded S11. A percentage bandwidth of 16.5% is achieved for the dimensions
Two consecutive unit cells of square AMC. (b) HFSS simulation setup. (c) Reflection phase (RP) of the square AMC with
A transverse-magnetic (TM) wave with its electric field (E-field) directed in the
Square AMC with incident TM wave polarized in the
The AMCs presented in Sections 2.2.1, and 2.2.2 are utilized to enhance the radiation characteristics of a circular OCA. First, the methodology presented in [14, 15] is maintained to guarantee high gain-to-active-area ratio. According to this method, a high gain-to-active-area ratio is possible by increasing the number of AMC cells in the direction of the antenna polarization and decreasing them at the normal to this direction. Figure 3(a) and (b) shows a top view and three-dimensional (3D) view of the OCA employing square AMC, respectively. Figure 3(c) displays a top view of the circular OCA on rectangular AMC. We designed the two structures (OCA on square AMC and OCA on rectangular AMC) with the dimensions listed in Table 1, and they have the same chip area of 840 × 1710 µm2.
\n\nAlso, the two structures have a high agreement in the matching performance, gain and efficiency responses, and current distribution as can be interpreted from Figure 3(d) and (f), respectively. The simulated gain and radiation efficiency are -0.8 dBi and 22.5%, respectively, at 60 GHz. These observations in Figure 3 stand as an additional proof that the symmetric square AMC and asymmetric rectangular AMC are equivalent for TM mode antennas.
\nIn the previous sections from 2.2.1 to 2.2.3, we have demonstrated that TM-mode circular OCA, which is exploiting the symmetric square AMC, and the asymmetric rectangular AMC undergo similar performances regarding impedance matching and radiation characteristics such as gain and efficiency. In this section, we detail how the asymmetric rectangular AMC can be modified such that the gain-to-active-area ratio can increase. Figure 4(a) shows the circular OCA over a modified asymmetric AMC. We applied the following adjustments to the asymmetric AMC:
\n\n\nRemoving the two AMC cells that lay directly below the OCA in Figure 3(c). Bao et al. [16] originally proposed this AMC cells removal for peak gain and axial ratio bandwidth boosting.
\nLimiting the length (
Adding circular rounds to the AMC cells near to the OCA as shown in Figure 4(a) and then adjusting the separation between the OCA and the modified AMC cells with circular rounds “d1” and the separation between the modified AMC cells with circular rounds “d2.”
\nTop view of circular OCA over square AMC. (b) 3D view of circular OCA over square AMC. (c) Top view of circular OCA over rectangular AMC. (d) Simulated |S11| comparison. (e) Simulated peak gain and efficiency comparison. (f) Simulated current distribution comparison (left: square AMC; right: rectangular AMC) “Reprinted with permission from Microwave Journal.”
450 | \n64 | \n85 | \n60 | \n14 | \n50 | \n54 | \n100 | \n254 | \n
Optimized dimensions of circular OCA employing square AMC.
Reprinted with permission from Microwave Journal.
By applying the above modifications to the asymmetric rectangular AMC, the resulting OCA over modified asymmetric AMC establishes a gain of 0 dBi at 60 GHz within a chip area of 1.19 mm2. The design dimensions are the same as in Table 1 except
Circular OCA over modified asymmetric AMC: (a) top view and (b) simulated |S11| and peak gain. “Reprinted with permission from Microwave Journal.”
In Section 2, the chapter focused on enhancing the gain-to-active-area ratio by employing a modified asymmetric AMC EM shield. Otherwise, this section presents a different procedure based on the semiconductor properties of the PN-junction (PNJ) to improve this ratio. A PNJ creation results from the coexistence of the P and N semiconductor types. A depletion layer, which is carriers’ free area, will appear between the two semiconductors’ types [22, 23]. Subsequently, in this section, we employ this depletion layer concept in the OCA’s gain-to-active-area ratio enrichment, as will be clarified in the following sections.
\nA PNJ is described by its built-in voltage (
Typically, a depletion area will be in the range of a few micrometers. However, we achieved a large depletion area by distributing N-type semiconductor within the P-type semiconductor in a manner for which all the targeted area has depleted. Figure 5 reveals how this criterion is possible. In Figure 5(a), rectangular-shaped N-type semiconductor cells are spread within the P-type with a cell width of
(a) Grid of rectangular-shaped N-type semiconductor on a P-type semiconductor with dimensions that satisfy full depletion condition and its equivalent depleted area. (b) Side view of the depleted region [
As shown in Figure 6(a), we have implemented the outsized depletion area below the OCA. This OCA is originally the OCA on modified asymmetric AMC shown in Figure 4(a). The depletion layer has the same dielectric constant as silicon (
Simulation comparison of the OCA with/without depletion layer below (a) cross-sectional view of the OCA with the depletion zone, (b) |S11|, (c) efficiency, and (d) peak gain [
Hereafter, we compare the simulated performance of the OCA on modified AMC with/without depletion area in terms of |S11|, radiation efficiency, and peak gain as shown in Figure 6(b)–(d), respectively. Both OCAs with/without depletion demonstrate a matched response (|S11|<-10 dB) at the bandwidth of interest around 60 GHz. Besides, the existence of the depletion layer leads to the improvement of the radiation efficiency and the peak gain of the OCA. The radiation efficiency is increased at 60 GHz from 25 to 32% as shown in Figure 6(c). Moreover, the peak gain at 60 GHz is improved from 0 to 1 dBi as illustrated in Figure 6(d). The optimized design dimensions of the OCA with depletion layer are similar to the one without depletion layer except
The 0.18-µm CMOS technology used is a TSMC six-metal process. These process six metals are denoted as M1–M6 from bottom to top. The top metal layer “M6” is selected for the circular OCA implementation and its feeding microstrip line for two reasons. First, it has the largest thickness and then it has lower conduction losses than the other metal layers (M1–M5). Second, M6 layer has the highest separation from the lossy CMOS substrate; hence, it should have the least coupling with the CMOS substrate and the lowest power leakage to it [19, 23]. The other metal layers (M1–M5) are used for the construction of the modified asymmetric AMC. We illustrate the specific layout tips in the following paragraph.
\nThe HFSS and Cadence Virtuoso layouts of the circular OCA on modified asymmetric AMC plan are shown in Figure 7(a) and (b), respectively. Also, a photograph of the fabricated OCA is provided in Figure 7(c). We performed a slight change in the feeding position. The modification in the feeding topology targeted the compensation of the measuring pads’ low impedance and capacitive nature. The pads’ coplanar waveguide (CPW) grounds at M6 are connected using via connections to M1 “the AMC unit cell.” Moreover, to fulfill design rules of the TSMC 0.18-μm CMOS process, the design has the following alternations:
\n(a) OCA layout at HFSS with dimensions. (b) OCA layout at Cadence Virtuoso. (c) Fabricated OCA.
The measurements are performed using a VNA (E8361C PNA 10 MHz to 67 GHz) and a Cascade Microtech manual probe station. A Cascade Microtech calibration kit with part number “101-190” allowed the ground-signal-ground (GSG) short-open-load-through (SOLT) Calibration for the infinity probe used to measure the |S11| of the fabricated OCAs.
\nFigure 8 shows the measured matching and gain performance of the OCAs without depletion. This OCA exhibits a matched behavior (|S11|<-10 dB) at the bandwidth of interest with good agreement with the simulated |S11| as shown in Figure 8(a). Also, it has a measured gain of -3 dB at 64 GHz as shown in Figure 8(b). The OCA with depletion area below has the same layout as in Figure 7 except that it has an additional grid of N-well (N-type material) with width of 2
The simulated and measured performances of the OCA on modified AMC without depletion (a) |S11| and (b) peak gain.
Simulated and measured performance of the OCA with depletion (
We used a simple setup based on the reference antenna gain method [24] for the OCA peak gain measurements shown in Figure 8(b) and Figure 9. First, we performed a VNA insertion loss response calibration by placing a two V-band standard gain horn (SGH) antennas separated by 1 m to calibrate all losses caused by including cables and free-space path loss. Second, the target OCA replaced the receiving SGH while keeping the same measuring distance between the two antennas, and insertion loss (
To enable the measurement of the OCA efficiency and radiation pattern, we used the advanced setup described in [25]. A photograph of the measurement setup is shown in Figure 10(a). For correct handling, the OCA is placed using supporting foam which is mostly invisible to the EM waves as shown in Figure 10(b). A piece of metal is placed below the chip to realize the package ground. We used this setup to characterize the OCA without depletion shown in Figure 7(c). The measured |S11| is in good agreement with the simulated |S11|and is identical to that in Figure 8(a) which was measured on probe station.
\n(a) Measurement setup. (b) Visualization of the measurements support structure. “Reprinted with permission from Microwave Journal.”
The measured peak gain has a discrepancy of up to 4 dB when compared to the simulated one as shown in Figure 11(a). This inconsistency resulted from the other fabricated structures surrounding the OCA, the probe pins, and the probe body which are not considered in simulations. So, we performed additional simulations to validate these gain measurements. In Figure 11(b), we show another simulation model which we used in this validation. This model considers the nearest fabricated structures which may affect the OCA performance. Using this model, the simulated peak gain noted as “With metals” in Figure 11(a) is in fair agreement with the measured results especially for frequencies up to 58 GHz. Other discrepancies between measured and simulated gain may be due to other metals which are not modeled, and also due to the ±0.8-dB accuracy of the measurement setup [25].
\n\nFinally, we present the measured E-plane and H-plane radiation patterns at 56, 60, and 64 GHz in Figure 12. The E-plane and H-plane are located at
(a) Measurement results using the setup in Ref. [
E-plane (top) and H-plane (down) radiation patterns at (a) 56GHz, (b) 60GHz, and (c) 64GHz. Measured (dashed) and simulated (solid). “Reprinted with permission from Microwave Journal.”
We have presented in this chapter two unconventional distinct techniques to improve the OCAs’ performance on CMOS technology regarding a high gain-to-active-area ratio. The first technique extended the concept of EM shielding using asymmetric AMC, then modified asymmetric AMC. The OCA based on modified asymmetric AMC realized a peak gain of -4 dBi within a chip area of 1.21 mm2. The second technique employed the PNJ depletion concept to form a large area of low loss. The OCA on modified asymmetric AMC and large depletion area showed a gain of -1.5 dBi on the same area of 1.21 mm2. The measured gain performances were lower than that predicted by simulation due to the sensitivity of the OCAs to the surrounding chip environment.
\nThe authors like to thank Prof. H. Kanaya of Kyushu University, Fukuoka, Japan, and Prof. R. Suga of Aoyama Gakuin University, Tokyo, Japan, for their support in the initial measurements. The authors are grateful for Prof. C. Luxey and Mr. A. Bisognin of the University of Nice Sophia-Antipolis, Nice, France, for performing the complete measurements of the OCA on modified asymmetric AMC. A part of this work is supported by a Grant-in-Aid for Scientific Research (C) (16K06301), and VLSI Design and Education Center partially (VDEC), the University of Tokyo in collaboration with CADENCE and Keysights Corporations.
\nFusion power is one of the few options capable of supplying abundant safe baseline energy to the world [1]. In 1955, John Lawson, working at Harwell, defined a condition for fusion power depending on plasma density
Their method in [3] was to write a “system code,” in their case a simple spreadsheet, to incorporate the key input parameters and equations to calculate key output parameters. Innovations were to use the fusion gain
Some example results using their code are shown in Figure 1. The fusion power with these scan conditions is seen to be almost independent of tokamak size, while key engineering conditions, such as the radial compressive stress at the top of tokamak, the magnetic field at the HTS conductors, and the wall loading power are all satisfactory. The purple open squares show the thickness of the shield, rising rapidly from 0.55 m major radius.
Some example results from the 2017 Costley system code scanning as a function of major radius for a constant fusion gain
Figure 1 describes how an integration of tokamak physics, HTS design, neutronics and computational fluid dynamics, and magnetohydrodynamic stress codes could help predict optimal tokamak design. To these, we must add codes for tritium breeding, heat transfer, design, construction, and decommissioning costs to produce a suite of codes that must be put together to predict a new spherical tokamak power plant design. It is with this aim that Tokamak Energy has invested in high-performance computational (HPC) capabilities.
The “system codes” which used to be implemented on Excel spreadsheets are greatly expanded and are verified by fitting experimental data from actual tokamaks like ST40. Future system codes are envisaged to use a single-design geometry to perform calculations automatically on a suite of tools involving physics, HTS magnet design, neutronics, heat flow, and engineering to obtain the parameters required to optimize a tokamak. The integration of system codes and tools used by multiple departments allows for an automated, iterative optimization of the tokamak design. HTS magnet codes need to consider quench protection and be compared to actual demo magnet experiments to verify their performance. The analytic stress equations, once commonly used, are now replaced by finite element codes whose performance can be judged by experimental data from the ST40 tokamak. The neutronics of HTS and biological shields is now rather straightforwardly assessed by activation foils under actual conditions and actual measurements of dose rates during shots. A major part of the successful operation of tokamak power plants depends on being able to breed tritium from the fusion neutrons interacting with lithium in a “blanket” within the biological shield. These are being designed using neutronics codes but to date have not been tested. “Process” codes have the particularly difficult job of computing the “cost of electricity” for given costs of capital borrowing and materials. They are not easy to check and can so easily be outdated by unforeseen world events. The integration of system codes and tools used by multiple departments allows for an automated, iterative, optimization of the tokamak design.
All these aspects of physics, engineering, heat flow, magnet design, neutronics, radiation damage, shielding, tritium breeding, and cost estimates are possible with separate codes, and the objective is to integrate them into a suite of codes using the same computer-aided design (CAD) geometry on the same hardware. For this purpose, a high-performance computer was purchased by Tokamak Energy. The Tokamak Energy HPC currently has over 600 cores and over 3 TB of RAM available to use and continuously uses thousands of CPU hours daily to resolve physics and neutronics problems. Figure 2 illustrates some of the principal applications and their codes used, with illustrations of the results they have given in hours by the high-performance computer illustrated at the center.
The Tokamak Energy high-performance computer and examples of some of its applications and widely used code. Clockwise from the top left; the design “FREECAD” computer-aided design code of ST40, an “ABAQUS “code image of the mesh representation of the design, “MCNP” the Monte Carlo Neutral Particle code showing the neutronics fluence of a possible power plant, “FISPACT” the fusion activation code plot of the ST40 inner vacuum vessel, the in-house “PFIT” code plots of the ST40 field line fits to ST40 image, heat transfer in the ST40 divertor, the “HEAT” heat transfer code plots of the temperature in the HTS coils of a power plant, the “ANSYS” code plot of the mechanical stresses in the ST40 tokamak, and the “RACOON” in-house code for calculating HTS performance. In the center is the Tokamak Energy high-performance computer with author GK.
Key technological advancements needed to complete integration of CAD geometry between the suite of codes is in mesh generators. Currently, all tools have their own meshing methods with outputs in various formats. Geometrical information required to build successful inputs to the system tools are envisaged to be integrated into the CAD data. For example, neutronics heat deposition calculations require material compositions and densities for input and can output maximum heat deposition per CAD part which can then be stored as part of the CAD data for input for heat flow tools. Upgrades to the system code will utilize this data and perform meshing to the required resolution for each CAD part which are required for the system tools.
The following sections will shed some light on how we are effectively using the HPC for streamlining the design process, with an emphasis here on shield design. The use of “tally tagging” with the neutronics code MCNP is to answer key questions on the performance of shields, such as where the neutrons and gammas responsible for core heating originate, and from what reactions.
Costley [4] showed that the triple product
The reduction in tokamak major radius (lines labeled in meters) which may be given by lower aspect ratios (X-axis) or by higher magnetic toroidal fields (Y-axis). The figure uses the equation shown from [
It is seen from Figure 3 that going to lower aspect ratios (leftward) or to higher toroidal fields (upward) gives similar triple products from smaller tokamaks with lower major radii. This result is important because tokamaks of ITER size may be defined as “megaprojects” (technically project over $1B: ITER is over $20B). Historical studies of megaprojects show that cost and time overruns are the norm rather than the exception [5]. The reasons are obvious enough: megaprojects tend to be too big for one company, or even one country. They become difficult to manage as the layers of management between boss and worker become longer. With smaller tokamak power plants, agility becomes possible when projects can adapt quickly to any design optimization. A breakthrough would be achieved when modular construction becomes possible with centralized manufacture remote from the construction site.
In the following sections, these two opportunities, spherical tokamaks and high-temperature superconductor magnets, will be explored in more detail. Figure 1 does also reveal the downside of spherical tokamaks. The purple open squares in Figure 1 show that the space available for shielding diminishes slowly at large major radii but eventually rather rapidly to zero at some smaller major radius. Much of the remainder of this chapter will explore the materials and mechanisms most appropriate to a fusion tokamak shield. Tungsten boride shields have proved one possible option for a fusion power plant, and their performance is examined and compared with other possibilities.
In 1983, Sykes, Turner and Patel [6] and later Peng and Strickler [7] predicted the high plasma pressures β possible with low aspect ratio spherical tokamaks. The theory showed that β could indeed be raised by a combination of low aspect ratio and high elongation. In 1998, the START spherical tokamak team at Culham Laboratory in the UK achieved a breakthrough by reaching β values of order 40% [8], compared to the 6% or so achieved in JET or the 4% or so expected in ITER.
A simple-minded explanation for these increases in efficiency is suggested by Figure 4 which shows the toroidal magnetic field
In a low aspect ratio, high elongation plasma (left in blue), the orbiting electrons spend more time close to the current carrying center column than in a conventional tokamak (right in red) from [
Bigger spherical tokamaks were soon built around the world, now upgraded to higher toroidal fields. These include MAST-UPRADE (0.55 Tesla) at Culham, UK [11], NSTX-U (1Tesla) at Princeton, USA [12], and GLOBUS M2 (0.82 Tesla) at St. Petersberg, Russia [13]. Most recently constructed with the highest design toroidal field of 3 Tesla is the ST40 at Tokamak Energy Ltd., Milton Park, UK. This company was started in 2009 and its founders included START pioneers Alan Sykes and Mikhail Gryaznevich [14]. Its aim was to exploit the twin technologies of spherical tokamaks and high-temperature superconductors. The ST40 design team was chaired by Alan Sykes in 2014. Engineer and draftsman John Ross rapidly iterated designs with pencil and drawing board which hardly changed when the design moved to computer-aided design. Figure 5 shows the design as of May 2019 when temperatures of 15x106 K were first achieved.
The ST40 tokamak in May 2019 when the milestone plasma temperature of 15x106 K was achieved. On the left is the engineering drawing along with the reconstruction of the plasma and optical image of the plasma.
Rapid development followed and ST40 moved to larger premises with space for a neutron shield and neutral beam injection to heat the plasma to the next milestone temperature of 100x106 K which was successfully achieved in February 2022. In designing the next generation of spherical tokamaks, HPC facilities will be important particularly in solving the gyro-kinetics used to predict the plasma turbulence and plasma confinement time.
Bednorz and Müller discovered high-temperature superconductors (HTSs) back in 1986 [15]. The theory remains uncertain. The important fact is that by 2010 it was possible to buy kilometer lengths of HTS tape just 0.1 mm thick and 12 mm wide. Under the optimized manufacturing conditions, now readily achieved by commercial suppliers, YBa2Cu3O7 (YBCO) has a superconducting critical temperature of ~90 K. State-of-the-art commercial tapes are now exhibiting engineering critical current densities >1000 A/mm2 at 20 K and 20 Tesla field applied perpendicular to the tape which is the lowest performance configuration [16].
In 2015, Tokamak Energy demonstrated a simple 25 cm radius HTS tokamak operating continuously for 29 hours under a live demonstration during the Royal Society Summer Exhibition as illustrated in Figure 6.
The high-temperature superconducting tokamak ST25HTS in operation after for 29 hours.
The more difficult task was to create the HTS coils needed for an operational tokamak. A key problem is quench protection when any defect or heating anomaly can create a local temperature rise above the transition temperature. With an insulated conductor, the current has nowhere to go and so it heats up quickly. This can spread to nearby superconductors and so the magnet quenches and could be destroyed. The problem can be avoided by removing any insulation between the tapes. The current from any localized normal region of tape can then spread over to neighboring tapes and any quench is avoided, but then the time constant for energizing the coil becomes impractically long. In research in the David Hawksworth HTS Magnet Laboratory at Tokamak Energy, a middle way of partial insulation has been developed with a precise inter-turn resistance between each tape layer to allow current transfer but avoid the time-constant problems. Figure 7 shows “Demo2”, a stack of six REBCO non-insulated pancakes with a diameter of 300 mm. Cooled to 20 K it is able to take a current of 3000 A and produce a peak field of over 10 Tesla. The magnet proved difficult to quench. It could be quenched by turning off the current, but the stored energy was dissipated within the magnet in the inter-turn resistance, and there was no system degradation [18].
The DEMO2 magnet constructed at Tokamak Energy [
Under construction at Tokamak Energy is a demonstration tokamak “Demo4” designed to operate at fields in the region of 20 Tesla with a full set of partially insulated HTS toroidal field coils.
Figure 8 illustrates a well-known challenge of spherical tokamaks. For a given central HTS core radius
The increase of shield thickness
A related dependence was shown by the open purple squares in Figure 1 as a function of major radius for constant aspect ratio
The main disadvantages of large size are cost and construction time, which did not appear in Figure 1. In practice, deciding the optimal size of a spherical tokamak power plant will be an optimization including these as well as outputs from plasma physics, HTS core construction, neutronics calculations, heat flow calculations, and structural engineering constraints.
The fusion power plants envisaged to use the D-T reaction when a deuterium and tritium ions collide to produce an alpha particle and a neutron 2D + 3T = 4He + n + 17.6 MeV. The helium alphas, being charged, tend to stay within the plasma and sustain its temperature. The neutrons, with 14.1 MeV energy, interact little with the plasma and escape to the inner and outer shields where their energy can be used to generate electricity and also to replenish the tritium ions by reactions with lithium in “blanket” layers within the shields. There are fewer size limitations to the outer shield, so this discussion will center on the optimization of the inner shield.
14.1 MeV neutrons are not easy to shield. They can be slowed down by multiple elastic collisions, moderation, or more quickly by inelastic (e.g. n, gamma) collisions. The moderation method is only practical for hydrogen moderators as the average value of the decrease in the natural logarithm of the neutron energy per collision is unity for natural hydrogen, but only 0.158 for carbon. The shield studies made for the Costley system code [3] results of Figure 1 supposed a layered shield with thick layers of cemented tungsten carbide and thinner layers of water. The fast neutron flux through such a shield is shown in Figure 9 taken from [20]. The half-attenuation shield distance is 53 mm. This relatively poor attenuation is possibly because of the relatively high atomic fractions of carbon and oxygen which give little attenuation to either neutrons or gammas.
The attenuation of fast neutrons (E > 0.1 MeV) though a layered shield of tungsten carbide (including with a tungsten boride inner layer) with intervening water channels for coolant and neutron moderation. The inset shows a vertical section [
Water coolant is now seen to have serious problems in a fusion power plant. The activation of 16O to 16N which decays with a 7.1-s half-life is one issue, and another is the desire for heat production at higher temperatures where the water vapor pressure becomes serious. Helium gas cooling has none of these problems.
Monolithic shields with varying fractions of tungsten and boron were examined [21, 22] and shown to give half-attenuation coefficients as low as 40 mm as seen in Figure 10. The neutron cross sections of tungsten and boron are shown as a function of energy in Figure 11. Tungsten is a key element as its neutron cross section has significant inelastic neutron (n, 2n) and (n, n’ gamma) reactions around the 1 to 10 MeV energies which reduce the 14.1 MeV neutrons to around 0.1 MeV energy. The 10B isotope has an absorption cross section which rises inversely with neutron velocity giving a highly significant absorption below 0.1 MeV, not far above the energies where they are captured by 10B which makes up around 20% of natural boron. The principal reactions occurring in a tungsten boride shield are illustrated in Figure 12. Let us consider each of the numbered processes.
The attenuation of neutrons though monolithic shields at 1400 mm major radii of boron carbides of varying composition, including a cemented borocarbide, pure tungsten, and tungsten carbide.
The neutron cross sections for tungsten (left) and for boron (right). For tungsten, the total (black), elastic (green, dashed), inelastic (red, dash-dot), (n,2n) (blue, dotted), and (n, gamma) (yellow) cross sections are shown. For boron, the minority (20%) 10B isotope (black) and the majority 11B isotope cross section (blue dashed) are shown. Below 10 keV, the 10B cross section follows an inverse velocity increase with decreasing neutron energy as show in the curve labeled 10Babs. The cross sections are from the Brookhaven National Nuclear Data Centre [
Some of the processes involved in a tungsten boride shield protecting a high-temperature superconducting core from fusion neutrons generated by a plasma. Tungsten atoms are large, while boron atoms are small. Protons are red, neutrons green, electrons blue, and gammas violet. Fusion is fueled continuously by injecting tritium ions usually by pellet injection. These hit deuterium ions to produce helium ions and fast neutrons. The six scattering processes indicated are discussed in the text.
The attenuation of fluence through a W2B5 shield for neutrons created in the plasma (red direct) and neutrons and gammas created inelastically in the shield (blue). There are no direct gammas. Inset are shown the energy spectrum of the direct neutrons (red upper right) and the indirect neutrons and gammas (blue lower left).
Elastic scattering (i) of neutrons. Tungsten makes a good reflector as its cross section of ~3 barns of elastic cross section per atom at 14 MeV and its high mass compared to a neutron ensures little recoil energy. Most neutrons are not reflected but continue forward with slightly reduced energy. Moderation (ii) occurs when incident neutrons collide with lighter atoms, like boron. The collisions exchange, or moderate, the neutron energy, therby reducing the transmitted power. The best moderator is hydrogen since its mass is almost the same as the neutron and the maximum energy is lost on collision. Inelastic (n,2n) (iii) reactions produce a different isotope of the same element. A typical reaction would be 183W + n = 182W + 2n + γ, which is highly beneficial transforming each high energy neutron into two lower-energy neutrons of a few MeV which are easier to shield.
Inelastic (n, n’ gamma) neutron scattering (iv) means that the incident neutron forms a new compound nucleus which quickly decays to release the neutron with an appreciably lower energy and with the emission of the excess energy in the form of a gamma. These gammas must then be shielded. (n, gamma) capture (v) is common at lower neutron energies. The neutron is absorbed to form a tungsten isotope with one higher atomic weight with the emission of gammas of significant energy (vi). The lower-energy neutrons produced by moderation or inelastic scattering become increasingly likely to be absorbed by isotopes such as 10B with a high neutron absorption cross section. Gammas are shielded by scattering from electrons in the shield atoms and thus need high atomic number (number of electrons per atom) and high number density (atoms/m3). Tungsten is a comparatively good element for a gamma shield, while boron is not.
More detailed information on the shield scattering process may be found by using the “tally tagging” feature of the MCNP code [24]. Fluence or energy deposition tallies generally total up all particles from all sources, reactions, atoms, and isotopes. Using tally tagging, the results can be broken down into any chosen set of these options. In order to limit the output file length, it is usually best to ask specific questions: “Did a neutron start in the plasma and survive all the way through the shield?” “Did a photon heating the HTS core get born in the core itself, or did it get born in the shield?” Each output contains a tally code of form CCCCCZZAAA.RRRRR where CCCCC optionally represents the origin tally cell number, ZZ the atom number, AAA the isotope number, and RRRRR the reaction type.
Another important refinement in fluence tallies is to separate them according to the angle the particle path makes with the normal to the tally surface. In the following examples, the angles were divided into six ranges 0o to 30o, 30o to 60o, 60o to 90o, 90o to 120o, 120o to 150o, and 150o to 180o. These subtend different solid angles, so these need to be corrected to give fluences per steradian.
Some results answering the question of where the neutrons originate from are given in Figure 13 which shows the fluences at angles <300 to the shield layers. The tally tagging distinguishes the tally volumes where each neutron originated. The red triangles show those neutrons originating in the plasma, although some elastic moderation will have occurred. The direct neutron energy spectrum at 100 mm into the shield shown inset in red at the bottom left of Figure 13 shows that this is a minor effect with elastic moderation caused by the tungsten and boron atoms giving the rapid half-attenuations of 0.24 and 0.8 MeV, respectively. The corresponding indirect neutron spectrum shown inset in blue at the bottom left of Figure 13 is from the tungsten (n, gamma) and (n, n’ gamma) reactions and is very broad and centered around 0.2 MeV. The corresponding gamma rays are seen to have a less broad distribution with some peaks centered around 1 MeV. The tally tagging feature can also identify the origin of the indirect fluence in more detail. It shows that most of the indirect neutrons come back from tungsten atoms further into the shield. The indirect gammas came equally from tungsten and boron atoms within a few centimeters of the fluence position.
An illustration of the energy dependence of the neutrons as they pass through a W2B5 shield is given in Figure 14. Neutrons incident on the shield make up a “pool” of 14 MeV neutrons which extends with decreasing fluence through the shield. At any shield position, a fraction “falls down the waterfall” to energies around 0.2 MeV. At the base of the “waterfall,” the neutrons lose further energy by moderation down a gently sloping riverbed. In W2B5 as their energy reaches 0.001 MeV energies, they soon become almost completely absorbed by 10B as in a porous sandy riverbed.
An illustration of the energy dependence of the neutrons passing through A W2B5 shield. Neutrons incident on the shield come from a “pool” at 14 MeV. This pool decreases in width through the shield as (n, n’ gamma) inelastic reactions produces an energy “waterfall” reducing the neutron energy to around 0.2 MeV. At the bottom of the waterfall, moderation reduces the energy gradually (the rocky riverbed) until energies are almost wholly absorbed by 10B (the sandy riverbed). The gammas produced by the inelastic scattering are absorbed in a few centimeters so that the diagram is valid throughout the bulk of the shield.
A simple model of the W2B5 shield is that the fluence of direct neutrons of around 14 MeV energy exists across the shield with around 30-mm half-attenuation distance. Inelastic (n, n’ gamma) reactions lower the neutron energy to around 0.2 MeV, but the resulting gamma rays are attenuated in only a few centimeters. Further moderation reduces the neutron energy to the level where they are absorbed by 10B. In a pure tungsten shield, the waterfall from 14 to 0.2 MeV is again present, but there is no 10B absorption, so once again low-energy neutrons build up steadily through the shield leading to an ever-increasing pool of low-energy neutrons.
W2B5 is exceptional in that its 10B absorption removes most neutrons within a localized region of the shield so that the energy spectrum is almost identical through the bulk of the shield.
The HTS core of a tokamak power plant needs to be kept at temperatures of order 20 K. The heat deposition into the core determines the cryogenic power necessary to maintain this low temperature. The power deposition is also a determinant of the HTS radiation damage. The neutron and gamma power depositions into the core have been evaluated previously, but here the tally tagging option of MCNP has been used to investigate the processes by which this heat arrives at the HTS material. Figure 15 shows the neutron and gamma contributions to the heat deposition into a fully cooled core region which includes the central inconel sleeve, the copper cladding surrounding the HTS, and the 316 L stainless inner vacuum vessel. It was established that the total HTS gamma heating was some four times larger than the total neutron heating [21]. It is clear from the figure that the largest gamma contributions arise around the HTS tape layers and the surrounding materials, copper cladding, and the inner vacuum vessel. Contributions from the shield layers are around an order of magnitude less and fall of rapidly into the shield. Direct gammas from the plasma and outer wall are very low.
The origins of the heat deposition into the cooled core of the tokamak including the inconel sleeve, HTS coils, copper cladding, and stainless inner vacuum vessel and shield layers as shown inset at the top of the figure. The major gamma component arises from the core components with the shield component decreasing rapidly. The neutron component is dominated by the direct contribution from the plasma itself and the outer wall reflector.
In contrast, the major contribution to the neutron heat deposition is from the plasma itself out at 1400 mm radius (way off the scale of the figure!). As described earlier at each shield layer, some of these neutrons are inelastically scattered to give much lower-energy neutrons which are soon absorbed, and gammas which are rapidly attenuated within the shield. Some 14 MeV neutrons do persist all through the shield and provide the bulk of the heat deposition. Neutrons inelastically scattered by the HTS core volume, and the shield give contributions which are significant but around an order of magnitude lower.
Again, the tally tagging feature of MCNP can be used to explore in more detail the elements, isotopes, and reactions which give rise to the heat deposition. Figure 16 shows the neutron (left) and gamma (right) contributions to the heat deposition in the actual HTS materials within the core (excluding heat into the cold inconel center rod and the 316 L stainless steel inner pressure vessel included in Figure 16). The figure shows that the direct neutron energy deposition is still dominated by the “direct” contributions, principally from neutrons generated within the plasma itself, but also from neutrons scattered from the tungsten and water reflector layers beyond the plasma. The next highest contribution is around 20 times lower and come from n (n’, gamma) interactions in the HTS material itself. In contrast, the principal gamma heating arises from (n, gamma), (n, n’ gamma), (n,2n), and fluorescence reactions. These tend to be largest close to and fall off quite rapidly into the shield layers. Direct gamma heating is negligible.
The originating positions and reactions responsible for the neutron energy deposition into the HTS core volumes of a spherical tokamak power plant. The colored upper band and labels record the various tally volumes contributing to the energy deposition. The different symbols record the reaction method. “Direct” refers to neutrons originating in the plasma core itself, most from the plasma, some from the outer reflector, both off the scale of the neutron graph.
The effects of these results on radiation damage are clear. Fast neutron damage will arise from the 14-MeV neutron fluence component which penetrates the shield. Gamma damage in contrast can be identified as coming from (n, n’ gamma) reactions in 63Cu from the heat-sink material surrounding the HTS tapes and from 56Fe and 58Ni in the Hastalloy of the HTS tapes. (n, gamma) reactions from 184W and 182W in the shield are significant but reduce rapidly into the shield.
Spherical tokamaks with HTS magnets are one of few options for safe, abundant energy on a small footprint. This chapter addresses a key issue: finding a material that can shield the HTS core while maintaining small major radius and low aspect ratio. It explores the operational performance of tungsten boride tokamak shields particularly using the tally tagging option of MCNP to detail the locations, atoms, and reactions contributing to neutron and gamma fluence and energy depositions. These studies have revealed that the W2B5 shield operation is dominated by the slightly moderated near 14 MeV neutrons produced in the plasma. At all positions well within the shield, this fluence of neutrons is attenuated by inelastic (n, n’ gamma) reactions to produce lower-energy neutrons which can be absorbed by 10B and gammas which are absorbed by tungsten in a few centimeters. Our HPC capability has been instrumental in our design process. It will be increasingly used in our quest for faster fusion.
The authors are most grateful to their colleagues at Tokamak Energy, particularly Jack Astbury, Guy Morgan, Chris Wilson, Sandeep Irukuvarghula, Greg Brittles, Tony Langtry, Peter Buxton, Robert Slade and George Smith for their contributions to this work.
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",metaTitle:"Waiver Policy",metaDescription:"We feel that financial barriers should never prevent researchers from publishing their research. With the need to make scientific research more publically available and support the benefits of Open Access, more institutions and funders have dedicated funds to assist their faculty members and researchers cover the APCs associated with publishing in Open Access. Below we have outlined several options available to secure financing for your Open Access publication.",metaKeywords:null,canonicalURL:"/page/waiver-policy",contentRaw:'[{"type":"htmlEditorComponent","content":"At IntechOpen, the majority of OAPFs are paid by an Author’s institution or funding agency - Institutions (73%) vs. Authors (23%).
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\\n"}]'},components:[{type:"htmlEditorComponent",content:'At IntechOpen, the majority of OAPFs are paid by an Author’s institution or funding agency - Institutions (73%) vs. Authors (23%).
\n\nThe first step in obtaining funds for your Open Access publication begins with your institution or library. IntechOpen’s publishing standards align with most institutional funding programs. Our advice is to petition your institution for help in financing your Open Access publication.
\n\nHowever, as Open Access becomes a more commonly used publishing option for the dissemination of scientific and scholarly content, in addition to institutions, there are a growing number of funders who allow the use of grants for covering OA publication costs, or have established separate funds for the same purpose.
\n\nPlease consult our Open Access Funding page to explore some of these funding opportunities and learn more about how you could finance your IntechOpen publication. Keep in mind that this list is not definitive, and while we are constantly updating and informing our Authors of new funding opportunities, we recommend that you always check with your institution first.
\n\nFor Authors who are unable to obtain funding from their institution or research funding bodies and still need help in covering publication costs, IntechOpen offers the possibility of applying for a Waiver.
\n\nOur mission is to support Authors in publishing their research and making an impact within the scientific community. Currently, 14% of Authors receive full waivers and 6% receive partial waivers.
\n\nWhile providing support and advice to all our international Authors, waiver priority will be given to those Authors who reside in countries that are classified by the World Bank as low-income economies. In this way, we can help ensure that the scientific work being carried out can make an impact within the worldwide scientific community, no matter where an Author might live.
\n\nThe application process is open after your submitted manuscript has been accepted for publication. To apply, please fill out a Waiver Request Form and send it to your Author Service Manager. If you have an official letter from your university or institution showing that funds for your OA publication are unavailable, please attach that as well. The Waiver Request will normally be addressed within one week from the application date. All chapters that receive waivers or partial waivers will be designated as such online.
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Life",subtitle:null,isOpenForSubmission:!1,hash:"f6000bc0eeed7fcf0277a2f8d75907d9",slug:"quality-of-life-and-quality-of-working-life",bookSignature:"Ana Alice Vilas Boas",coverURL:"https://cdn.intechopen.com/books/images_new/5761.jpg",editedByType:"Edited by",editors:[{id:"175373",title:"Dr.",name:"Ana Alice",middleName:null,surname:"Vilas Boas",slug:"ana-alice-vilas-boas",fullName:"Ana Alice Vilas Boas"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],booksByTopicTotal:7,seriesByTopicCollection:[],seriesByTopicTotal:0,mostCitedChapters:[{id:"66422",doi:"10.5772/intechopen.85463",title:"Vulnerability and Social Exclusion: Risk in Adolescence and Old Age",slug:"vulnerability-and-social-exclusion-risk-in-adolescence-and-old-age",totalDownloads:1157,totalCrossrefCites:8,totalDimensionsCites:11,abstract:"Vulnerability can be defined as the quality or state of being exposed to the possibility of being attacked or harmed, either physically or emotionally. In this chapter, it is defined as a possible ability of an individual or a group to face, manage, and anticipate a possible problem. This concept of vulnerability is associated with that of risk factor for social isolation, and therefore to situations that can also lead to illness and lack of mental and physical health. It can have its roots in poverty, in social exclusion, in ethnicity, in disability or simply in disease or specific developmental phases in life. All these aspects reflect very important vulnerability factors among biological, psychological, social, and behavioral variables. To date, no one has highlighted together two critical moments in life in which this brain area undergoes important variations: adolescence, in which its development occurs, and old age, in which this area goes into cognitive decline with the relative loss of many higher cognitive functions. This knowledge can help to better understand the forms of exclusion due to vulnerability in order to develop new forms of social inclusion.",book:{id:"8262",slug:"the-new-forms-of-social-exclusion",title:"The New Forms of Social Exclusion",fullTitle:"The New Forms of Social Exclusion"},signatures:"Rosalba Morese, Sara Palermo, Matteo Defedele, Juri Nervo and Alberto Borraccino",authors:[{id:"214435",title:"Dr.",name:"Rosalba",middleName:null,surname:"Morese",slug:"rosalba-morese",fullName:"Rosalba Morese"},{id:"218983",title:"BSc.",name:"Juri",middleName:null,surname:"Nervo",slug:"juri-nervo",fullName:"Juri Nervo"},{id:"218984",title:"MSc.",name:"Matteo",middleName:null,surname:"Defedele",slug:"matteo-defedele",fullName:"Matteo Defedele"},{id:"233998",title:"Ph.D.",name:"Sara",middleName:null,surname:"Palermo",slug:"sara-palermo",fullName:"Sara Palermo"},{id:"266453",title:"Prof.",name:"Alberto",middleName:null,surname:"Borraccino",slug:"alberto-borraccino",fullName:"Alberto Borraccino"}]},{id:"74550",doi:"10.5772/intechopen.95395",title:"School Conflicts: Causes and Management Strategies in Classroom Relationships",slug:"school-conflicts-causes-and-management-strategies-in-classroom-relationships",totalDownloads:2308,totalCrossrefCites:1,totalDimensionsCites:10,abstract:"Conflicts cannot cease to exist, as they are intrinsic to human beings, forming an integral part of their moral and emotional growth. Likewise, they exist in all schools. The school is inserted in a space where the conflict manifests itself daily and assumes relevance, being the result of the multiple interpersonal relationships that occur in the school context. Thus, conflict is part of school life, which implies that teachers must have the skills to manage conflict constructively. Recognizing the diversity of school conflicts, this chapter aimed to present its causes, highlighting the main ones in the classroom, in the teacher-student relationship. It is important to conflict face and resolve it with skills to manage it properly and constructively, establishing cooperative relationships, and producing integrative solutions. Harmony and appreciation should coexist in a classroom environment and conflict should not interfere, negatively, in the teaching and learning process. This bibliography review underscore the need for during the teachers’ initial training the conflict management skills development.",book:{id:"7827",slug:"interpersonal-relationships",title:"Interpersonal Relationships",fullTitle:"Interpersonal Relationships"},signatures:"Sabina Valente, Abílio Afonso Lourenço and Zsolt Németh",authors:[{id:"324514",title:"Ph.D.",name:"Sabina",middleName:"N.",surname:"Valente",slug:"sabina-valente",fullName:"Sabina Valente"},{id:"326375",title:"Prof.",name:"Abílio Afonso",middleName:"Afonso",surname:"Lourenço",slug:"abilio-afonso-lourenco",fullName:"Abílio Afonso Lourenço"},{id:"329177",title:"Dr.",name:"Zsolt",middleName:null,surname:"Németh",slug:"zsolt-nemeth",fullName:"Zsolt Németh"}]},{id:"55323",doi:"10.5772/intechopen.68873",title:"Positive Psychology: The Use of the Framework of Achievement Bests to Facilitate Personal Flourishing",slug:"positive-psychology-the-use-of-the-framework-of-achievement-bests-to-facilitate-personal-flourishing",totalDownloads:1737,totalCrossrefCites:3,totalDimensionsCites:9,abstract:"The Framework of Achievement Bests, which was recently published in Educational Psychology Review, makes a theoretical contribution to the study of positive psychology. The Framework of Achievement Bests provides an explanatory account of a person’s optimal best practice from his/her actual best. Another aspect emphasizes on the saliency of the psychological process of optimization, which is central to our understanding of person’s optimal functioning in a subject matter. Achieving an exceptional level of best practice (e.g. achieving excellent grades in mathematics) does not exist in isolation, but rather depends on the potent impact of optimization. This chapter, theoretical in nature, focuses on an in‐depth examination of the expansion of the Framework of Achievement Bests. Our discussion of the Framework of Achievement Bests, reflecting a methodical conceptualization, is benchmarked against another notable theory for understanding, namely: Martin Seligman’s PERMA theory. For example, for consideration, one aspect that we examine entails the extent to which the Framework of Achievement Bests could explain the optimization of each of the five components of PERMA (e.g. how does the Framework of Achievement Bests explain the optimization of engagement?).",book:{id:"5761",slug:"quality-of-life-and-quality-of-working-life",title:"Quality of Life and Quality of Working Life",fullTitle:"Quality of Life and Quality of Working Life"},signatures:"Huy P. Phan and Bing H. Ngu",authors:[{id:"196435",title:"Prof.",name:"Huy",middleName:"P",surname:"Phan",slug:"huy-phan",fullName:"Huy Phan"}]},{id:"55349",doi:"10.5772/intechopen.68596",title:"The Development of a Human Well-Being Index for the United States",slug:"the-development-of-a-human-well-being-index-for-the-united-states",totalDownloads:2041,totalCrossrefCites:3,totalDimensionsCites:9,abstract:"The US Environmental Protection Agency (EPA) has developed a human well-being index (HWBI) that assesses the over-all well-being of its population at the county level. The HWBI contains eight domains representing social, economic and environmental well-being. These domains include 25 indicators comprised of 80 metrics and 22 social, economic and environmental services. The application of the HWBI has been made for the nation as a whole at the county level and two alternative applications have been made to represent key populations within the overall US population—Native Americans and children. A number of advances have been made to estimate the values of metrics for counties where no data is available and one such estimator—MERLIN—is discussed. Finally, efforts to make the index into an interactive web site are described.",book:{id:"5761",slug:"quality-of-life-and-quality-of-working-life",title:"Quality of Life and Quality of Working Life",fullTitle:"Quality of Life and Quality of Working Life"},signatures:"J. Kevin Summers, Lisa M. Smith, Linda C. Harwell and Kyle D. Buck",authors:[{id:"197485",title:"Dr.",name:"J. Kevin",middleName:null,surname:"Summers",slug:"j.-kevin-summers",fullName:"J. Kevin Summers"},{id:"197486",title:"Ms.",name:"Lisa",middleName:null,surname:"Smith",slug:"lisa-smith",fullName:"Lisa Smith"},{id:"197487",title:"Ms.",name:"Linda",middleName:null,surname:"Harwell",slug:"linda-harwell",fullName:"Linda Harwell"},{id:"197488",title:"Dr.",name:"Kyle",middleName:null,surname:"Buck",slug:"kyle-buck",fullName:"Kyle Buck"}]},{id:"56529",doi:"10.5772/intechopen.70237",title:"Well-being and Quality of Working Life of University Professors in Brazil",slug:"well-being-and-quality-of-working-life-of-university-professors-in-brazil",totalDownloads:1676,totalCrossrefCites:2,totalDimensionsCites:6,abstract:"This chapter presents a study about the perceptions on quality of working life (QWL) regarding factors and indicator in two public universities in Brazil. It aimed also to analyze their perceptions about university working conditions. This exploratory study is based on quantitative and qualitative analyses. A sample of 715 university professors participated on the research. Data collection was carried out in two steps: online survey and focus groups. There is a moderate negative correlation between psychological well-being and work-related stress. Emotional charge also presents a moderate positive correlation with work-related stress, as well as physical charge and psychological distress. Work-life balance is negatively correlated with physical charge, emotional charge, work-related stress, psychological distress, and burnout. We observed also that 43.6% of the professors reported high levels of work-related stress in their everyday work. The precariousness of university teaching is associated with three main elements, which we defined as the tripod of the precarization of university teaching work. It consists of academic productivism, excess of administrative work and bureaucratic activities, and inadequate working conditions. The operating dynamics of this tripod effect professors’ well-being, their QWL, and even the quality of the work they develop in public universities.",book:{id:"5761",slug:"quality-of-life-and-quality-of-working-life",title:"Quality of Life and Quality of Working Life",fullTitle:"Quality of Life and Quality of Working Life"},signatures:"Alessandro Vinicius de Paula and Ana Alice Vilas Boas",authors:[{id:"175373",title:"Dr.",name:"Ana Alice",middleName:null,surname:"Vilas Boas",slug:"ana-alice-vilas-boas",fullName:"Ana Alice Vilas Boas"},{id:"196534",title:"Dr.",name:"Alessandro Vinicius",middleName:null,surname:"De Paula",slug:"alessandro-vinicius-de-paula",fullName:"Alessandro Vinicius De Paula"}]}],mostDownloadedChaptersLast30Days:[{id:"74550",title:"School Conflicts: Causes and Management Strategies in Classroom Relationships",slug:"school-conflicts-causes-and-management-strategies-in-classroom-relationships",totalDownloads:2328,totalCrossrefCites:1,totalDimensionsCites:10,abstract:"Conflicts cannot cease to exist, as they are intrinsic to human beings, forming an integral part of their moral and emotional growth. Likewise, they exist in all schools. The school is inserted in a space where the conflict manifests itself daily and assumes relevance, being the result of the multiple interpersonal relationships that occur in the school context. Thus, conflict is part of school life, which implies that teachers must have the skills to manage conflict constructively. Recognizing the diversity of school conflicts, this chapter aimed to present its causes, highlighting the main ones in the classroom, in the teacher-student relationship. It is important to conflict face and resolve it with skills to manage it properly and constructively, establishing cooperative relationships, and producing integrative solutions. Harmony and appreciation should coexist in a classroom environment and conflict should not interfere, negatively, in the teaching and learning process. This bibliography review underscore the need for during the teachers’ initial training the conflict management skills development.",book:{id:"7827",slug:"interpersonal-relationships",title:"Interpersonal Relationships",fullTitle:"Interpersonal Relationships"},signatures:"Sabina Valente, Abílio Afonso Lourenço and Zsolt Németh",authors:[{id:"324514",title:"Ph.D.",name:"Sabina",middleName:"N.",surname:"Valente",slug:"sabina-valente",fullName:"Sabina Valente"},{id:"326375",title:"Prof.",name:"Abílio Afonso",middleName:"Afonso",surname:"Lourenço",slug:"abilio-afonso-lourenco",fullName:"Abílio Afonso Lourenço"},{id:"329177",title:"Dr.",name:"Zsolt",middleName:null,surname:"Németh",slug:"zsolt-nemeth",fullName:"Zsolt Németh"}]},{id:"76968",title:"In the Darkness of This Time: Wittgenstein and Freud on Uncertainty",slug:"in-the-darkness-of-this-time-wittgenstein-and-freud-on-uncertainty",totalDownloads:461,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"Both Wittgenstein and Freud experienced the crisis of humanism resulting from the first and second world wars. Although they were both considered to be influential figures, they hardly investigated the ways in which people could cope with the consequences of these crises. However, Wittgenstein and Freud did suggest ways of understanding uncertainties caused by real life events, as well as by the nature of human thought processes. This article will explore the therapeutic ways of dealing with uncertainties common to both thinkers and the different concepts facilitating their methodologies. The central contention of this article is that both Wittgenstein and Freud developed a complex methodology, acknowledging the constant and unexpected changes humans have deal with, whilst also offering the possibility of defining “hinge propositions” and “language-games” which can stabilize our consciousness.",book:{id:"10814",slug:"anxiety-uncertainty-and-resilience-during-the-pandemic-period-anthropological-and-psychological-perspectives",title:"Anxiety, Uncertainty, and Resilience During the Pandemic Period",fullTitle:"Anxiety, Uncertainty, and Resilience During the Pandemic Period - Anthropological and Psychological Perspectives"},signatures:"Dorit Lemberger",authors:[{id:"325725",title:"Dr.",name:"Dorit",middleName:null,surname:"Lemberger",slug:"dorit-lemberger",fullName:"Dorit Lemberger"}]},{id:"76565",title:"Introductory Chapter: The Transition from Distress to Acceptance of Human Frailty - Anthropology and Psychology of the Pandemic Era",slug:"introductory-chapter-the-transition-from-distress-to-acceptance-of-human-frailty-anthropology-and-ps",totalDownloads:393,totalCrossrefCites:0,totalDimensionsCites:0,abstract:null,book:{id:"10814",slug:"anxiety-uncertainty-and-resilience-during-the-pandemic-period-anthropological-and-psychological-perspectives",title:"Anxiety, Uncertainty, and Resilience During the Pandemic Period",fullTitle:"Anxiety, Uncertainty, and Resilience During the Pandemic Period - Anthropological and Psychological Perspectives"},signatures:"Fabio Gabrielli and Floriana Irtelli",authors:[{id:"174641",title:"Dr.",name:"Floriana",middleName:null,surname:"Irtelli",slug:"floriana-irtelli",fullName:"Floriana Irtelli"},{id:"259407",title:"Prof.",name:"Fabio",middleName:null,surname:"Gabrielli",slug:"fabio-gabrielli",fullName:"Fabio Gabrielli"}]},{id:"77214",title:"The Impact of the COVID-19 Pandemic on the Mental Health of Dentists",slug:"the-impact-of-the-covid-19-pandemic-on-the-mental-health-of-dentists",totalDownloads:390,totalCrossrefCites:1,totalDimensionsCites:1,abstract:"Since March 2020, the COVID-19 disease has declared a pandemic producing a worldwide containment. For months, many people were subjected to strict social isolation away from family and loved ones to prevent disease transmission, leading to anxiety, fear, and depression. On the other hand, many had to close down their businesses and stop working, resulting in financial issues. Previous studies have reported that pandemics, epidemics, and some diseases can lead to mental disorders such as fear, anxiety, stress, and depression. Among those most affected, healthcare workers (HCWs), especially those on the front line, often develop mental health problems. Although there is data available on the management and care of HCWs, little attention has been paid to the mental health and well-being of dentists during the COVID-19 pandemic. Therefore, this chapter aims to review the impact of the COVID-19 pandemic on dentists’ mental health and mental health-related symptoms. Finally, to recommend specific measures to avoid consequent potential implications for dentists, dental students, and dental patients.",book:{id:"10814",slug:"anxiety-uncertainty-and-resilience-during-the-pandemic-period-anthropological-and-psychological-perspectives",title:"Anxiety, Uncertainty, and Resilience During the Pandemic Period",fullTitle:"Anxiety, Uncertainty, and Resilience During the Pandemic Period - Anthropological and Psychological Perspectives"},signatures:"Andrea Vergara-Buenaventura and Carmen Castro-Ruiz",authors:[{id:"346660",title:"M.Sc.",name:"Andrea",middleName:null,surname:"Vergara-Buenaventura",slug:"andrea-vergara-buenaventura",fullName:"Andrea Vergara-Buenaventura"},{id:"419814",title:"MSc.",name:"Carmen",middleName:null,surname:"Castro-Ruiz",slug:"carmen-castro-ruiz",fullName:"Carmen Castro-Ruiz"}]},{id:"55323",title:"Positive Psychology: The Use of the Framework of Achievement Bests to Facilitate Personal Flourishing",slug:"positive-psychology-the-use-of-the-framework-of-achievement-bests-to-facilitate-personal-flourishing",totalDownloads:1748,totalCrossrefCites:3,totalDimensionsCites:9,abstract:"The Framework of Achievement Bests, which was recently published in Educational Psychology Review, makes a theoretical contribution to the study of positive psychology. The Framework of Achievement Bests provides an explanatory account of a person’s optimal best practice from his/her actual best. Another aspect emphasizes on the saliency of the psychological process of optimization, which is central to our understanding of person’s optimal functioning in a subject matter. Achieving an exceptional level of best practice (e.g. achieving excellent grades in mathematics) does not exist in isolation, but rather depends on the potent impact of optimization. This chapter, theoretical in nature, focuses on an in‐depth examination of the expansion of the Framework of Achievement Bests. Our discussion of the Framework of Achievement Bests, reflecting a methodical conceptualization, is benchmarked against another notable theory for understanding, namely: Martin Seligman’s PERMA theory. For example, for consideration, one aspect that we examine entails the extent to which the Framework of Achievement Bests could explain the optimization of each of the five components of PERMA (e.g. how does the Framework of Achievement Bests explain the optimization of engagement?).",book:{id:"5761",slug:"quality-of-life-and-quality-of-working-life",title:"Quality of Life and Quality of Working Life",fullTitle:"Quality of Life and Quality of Working Life"},signatures:"Huy P. Phan and Bing H. 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He is a full professor of signal processing and pattern recognition and is head of the Signals and Communications Department at ULPGC, teaching from 2001 on subjects on signal processing and learning theory. His research lines are biometrics, biomedical signals and images, data mining, classification system, signal and image processing, machine learning, and environmental intelligence. He has researched in 52 international and Spanish research projects, some of them as head researcher. He is co-author of 4 books, co-editor of 27 proceedings books, guest editor for 8 JCR-ISI international journals, and up to 24 book chapters. He has over 450 papers published in international journals and conferences (81 of them indexed on JCR – ISI - Web of Science). He has published seven patents in the Spanish Patent and Trademark Office. He has been a supervisor on 8 Ph.D. theses (11 more are under supervision), and 130 master theses. 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He has been a member of the IASTED Technical Committee on Image Processing from 2007 and a member of the IASTED Technical Committee on Artificial Intelligence and Expert Systems from 2011. \n\nHe has held the general chair position for the following: ACM-APPIS (2020, 2021), IEEE-IWOBI (2019, 2020 and 2020), A PPIS (2018, 2019), IEEE-IWOBI (2014, 2015, 2017, 2018), InnoEducaTIC (2014, 2017), IEEE-INES (2013), NoLISP (2011), JRBP (2012), and IEEE-ICCST (2005)\n\nHe is an associate editor of the Computational Intelligence and Neuroscience Journal (Hindawi – Q2 JCR-ISI). He was vice dean from 2004 to 2010 in the Higher Technical School of Telecommunication Engineers at ULPGC and the vice dean of Graduate and Postgraduate Studies from March 2013 to November 2017. 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His research interests include computer/machine vision, machine learning, pattern recognition, computational intelligence. \nDr. Papakostas served as a reviewer in numerous journals, as a program\ncommittee member in international conferences and he is a member of the IAENG, MIR Labs, EUCogIII, INSTICC and the Technical Chamber of Greece (TEE).",institutionString:null,institution:{name:"International Hellenic University",institutionURL:null,country:{name:"Greece"}}},editorTwo:null,editorThree:null},{id:"25",title:"Evolutionary Computation",coverUrl:"https://cdn.intechopen.com/series_topics/covers/25.jpg",isOpenForSubmission:!0,editor:{id:"136112",title:"Dr.",name:"Sebastian",middleName:null,surname:"Ventura Soto",slug:"sebastian-ventura-soto",fullName:"Sebastian Ventura Soto",profilePictureURL:"https://mts.intechopen.com/storage/users/136112/images/system/136112.png",biography:"Sebastian Ventura is a Spanish researcher, a full professor with the Department of Computer Science and Numerical Analysis, University of Córdoba. 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He is currently a principal researcher in data analytics and optimisation at TECNALIA (Spain), a visiting fellow at the Basque Center for Applied Mathematics (BCAM) and a part-time lecturer at the University of the Basque Country (UPV/EHU). His research interests gravitate on the use of descriptive, prescriptive and predictive algorithms for data mining and optimization in a diverse range of application fields such as Energy, Transport, Telecommunications, Health and Industry, among others. In these fields he has published more than 240 articles, co-supervised 8 Ph.D. theses, edited 6 books, coauthored 7 patents and participated/led more than 40 research projects. 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He is currently a full professor in\nthe Department of Automation and Applied Informatics at the\nsame university. Dr. Voloşencu is the author of ten books, seven\nbook chapters, and more than 160 papers published in journals\nand conference proceedings. He has also edited twelve books and\nhas twenty-seven patents to his name. He is a manager of research grants, editor in\nchief and member of international journal editorial boards, a former plenary speaker, a member of scientific committees, and chair at international conferences. His\nresearch is in the fields of control systems, control of electric drives, fuzzy control\nsystems, neural network applications, fault detection and diagnosis, sensor network\napplications, monitoring of distributed parameter systems, and power ultrasound\napplications. 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After almost 32 years of teaching at the University of Trás-os-Montes and Alto Douro, she recently moved to the University of Évora, Department of Veterinary Medicine, where she teaches in the field of Animal Reproduction and Clinics. Her primary research areas include the molecular markers of the endometrial cycle and the embryo–maternal interaction, including oxidative stress and the reproductive physiology and disorders of sexual development, besides the molecular determinants of male and female fertility. She often supervises students preparing their master's or doctoral theses. She is also a frequent referee for various journals.",institutionString:null,institution:{name:"University of Évora",country:{name:"Portugal"}}},{id:"283019",title:"Dr.",name:"Oudessa",middleName:null,surname:"Kerro Dego",slug:"oudessa-kerro-dego",fullName:"Oudessa Kerro Dego",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/283019/images/system/283019.png",biography:"Dr. Kerro Dego is a veterinary microbiologist with training in veterinary medicine, microbiology, and anatomic pathology. Dr. Kerro Dego is an assistant professor of dairy health in the department of animal science, the University of Tennessee, Institute of Agriculture, Knoxville, Tennessee. He received his D.V.M. (1997), M.S. (2002), and Ph.D. (2008) degrees in Veterinary Medicine, Animal Pathology and Veterinary Microbiology from College of Veterinary Medicine, Addis Ababa University, Ethiopia; College of Veterinary Medicine, Utrecht University, the Netherlands and Western College of Veterinary Medicine, University of Saskatchewan, Canada respectively. He did his Postdoctoral training in microbial pathogenesis (2009 - 2015) in the Department of Animal Science, the University of Tennessee, Institute of Agriculture, Knoxville, Tennessee. Dr. Kerro Dego’s research focuses on the prevention and control of infectious diseases of farm animals, particularly mastitis, improving dairy food safety, and mitigation of antimicrobial resistance. Dr. Kerro Dego has extensive experience in studying the pathogenesis of bacterial infections, identification of virulence factors, and vaccine development and efficacy testing against major bacterial mastitis pathogens. Dr. Kerro Dego conducted numerous controlled experimental and field vaccine efficacy studies, vaccination, and evaluation of immunological responses in several species of animals, including rodents (mice) and large animals (bovine and ovine).",institutionString:"University of Tennessee at Knoxville",institution:{name:"University of Tennessee at Knoxville",country:{name:"United States of America"}}},{id:"251314",title:"Dr.",name:"Juan Carlos",middleName:null,surname:"Gardón Poggi",slug:"juan-carlos-gardon-poggi",fullName:"Juan Carlos Gardón Poggi",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/251314/images/system/251314.jpeg",biography:"Juan Carlos Gardón Poggi received University degree from the Faculty of Agrarian Science in Argentina, in 1983. Also he received Masters Degree and PhD from Córdoba University, Spain. He is currently a Professor at the Catholic University of Valencia San Vicente Mártir, at the Department of Medicine and Animal Surgery. He teaches diverse courses in the field of Animal Reproduction and he is the Director of the Veterinary Farm. He also participates in academic postgraduate activities at the Veterinary Faculty of Murcia University, Spain. His research areas include animal physiology, physiology and biotechnology of reproduction either in males or females, the study of gametes under in vitro conditions and the use of ultrasound as a complement to physiological studies and development of applied biotechnologies. Routinely, he supervises students preparing their doctoral, master thesis or final degree projects.",institutionString:null,institution:{name:"Valencia Catholic University Saint Vincent Martyr",country:{name:"Spain"}}},{id:"309529",title:"Dr.",name:"Albert",middleName:null,surname:"Rizvanov",slug:"albert-rizvanov",fullName:"Albert Rizvanov",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/309529/images/9189_n.jpg",biography:'Albert A. Rizvanov is a Professor and Director of the Center for Precision and Regenerative Medicine at the Institute of Fundamental Medicine and Biology, Kazan Federal University (KFU), Russia. He is the Head of the Center of Excellence “Regenerative Medicine” and Vice-Director of Strategic Academic Unit \\"Translational 7P Medicine\\". Albert completed his Ph.D. at the University of Nevada, Reno, USA and Dr.Sci. at KFU. He is a corresponding member of the Tatarstan Academy of Sciences, Russian Federation. Albert is an author of more than 300 peer-reviewed journal articles and 22 patents. He has supervised 11 Ph.D. and 2 Dr.Sci. dissertations. Albert is the Head of the Dissertation Committee on Biochemistry, Microbiology, and Genetics at KFU.\nORCID https://orcid.org/0000-0002-9427-5739\nWebsite https://kpfu.ru/Albert.Rizvanov?p_lang=2',institutionString:"Kazan Federal University",institution:{name:"Kazan Federal University",country:{name:"Russia"}}},{id:"210551",title:"Dr.",name:"Arbab",middleName:null,surname:"Sikandar",slug:"arbab-sikandar",fullName:"Arbab Sikandar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/210551/images/system/210551.jpg",biography:"Dr. Arbab Sikandar, PhD, M. Phil, DVM was born on April 05, 1981. He is currently working at the College of Veterinary & Animal Sciences as an Assistant Professor. He previously worked as a lecturer at the same University. \nHe is a Member/Secretory of Ethics committee (No. CVAS-9377 dated 18-04-18), Member of the QEC committee CVAS, Jhang (Regr/Gen/69/873, dated 26-10-2017), Member, Board of studies of Department of Basic Sciences (No. CVAS. 2851 Dated. 12-04-13, and No. CVAS, 9024 dated 20/11/17), Member of Academic Committee, CVAS, Jhang (No. CVAS/2004, Dated, 25-08-12), Member of the technical committee (No. CVAS/ 4085, dated 20,03, 2010 till 2016).\n\nDr. Arbab Sikandar contributed in five days hands-on-training on Histopathology at the Department of Pathology, UVAS from 12-16 June 2017. He received a Certificate of appreciation for contributions for Popularization of Science and Technology in the Society on 17-11-15. He was the resource person in the lecture series- ‘scientific writing’ at the Department of Anatomy and Histology, UVAS, Lahore on 29th October 2015. He won a full fellowship as a principal candidate for the year 2015 in the field of Agriculture, EICA, Egypt with ref. to the Notification No. 12(11) ACS/Egypt/2014 from 10 July 2015 to 25th September 2015.; he received a grant of Rs. 55000/- as research incentives from Director, Advanced Studies and Research, UVAS, Lahore upon publications of research papers in IF Journals (DR/215, dated 19-5-2014.. He obtained his PhD by winning a HEC Pakistan indigenous Scholarship, ‘Ph.D. fellowship for 5000 scholars – Phase II’ (2av1-147), 17-6/HEC/HRD/IS-II/12, November 15, 2012. \n\nDr. Sikandar is a member of numerous societies: Registered Veterinary Medical Practitioner (life member) and Registered Veterinary Medical Faculty of Pakistan Veterinary Medical Council. The Registration code of PVMC is RVMP/4298 and RVMF/ 0102.; Life member of the University of Veterinary and Animal Sciences, Lahore, Alumni Association with S# 664, dated: 6-4-12. ; Member 'Vets Care Organization Pakistan” with Reference No. VCO-605-149, dated 05-04-06. :Member 'Vet Crescent” (Society of Animal Health and Production), UVAS, Lahore.",institutionString:"University of Veterinary & Animal Science",institution:{name:"University of Veterinary and Animal Sciences",country:{name:"Pakistan"}}},{id:"311663",title:"Dr.",name:"Prasanna",middleName:null,surname:"Pal",slug:"prasanna-pal",fullName:"Prasanna Pal",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/311663/images/13261_n.jpg",biography:null,institutionString:null,institution:{name:"National Dairy Research Institute",country:{name:"India"}}},{id:"202192",title:"Dr.",name:"Catrin",middleName:null,surname:"Rutland",slug:"catrin-rutland",fullName:"Catrin Rutland",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/202192/images/system/202192.png",biography:"Catrin Rutland is an Associate Professor of Anatomy and Developmental Genetics at the University of Nottingham, UK. She obtained a BSc from the University of Derby, England, a master’s degree from Technische Universität München, Germany, and a Ph.D. from the University of Nottingham. She undertook a post-doctoral research fellowship in the School of Medicine before accepting tenure in Veterinary Medicine and Science. Dr. Rutland also obtained an MMedSci (Medical Education) and a Postgraduate Certificate in Higher Education (PGCHE). She is the author of more than sixty peer-reviewed journal articles, twelve books/book chapters, and more than 100 research abstracts in cardiovascular biology and oncology. She is a board member of the European Association of Veterinary Anatomists, Fellow of the Anatomical Society, and Senior Fellow of the Higher Education Academy. Dr. Rutland has also written popular science books for the public. https://orcid.org/0000-0002-2009-4898. www.nottingham.ac.uk/vet/people/catrin.rutland",institutionString:null,institution:{name:"University of Nottingham",country:{name:"United Kingdom"}}},{id:"283315",title:"Prof.",name:"Samir",middleName:null,surname:"El-Gendy",slug:"samir-el-gendy",fullName:"Samir El-Gendy",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRduYQAS/Profile_Picture_1606215849748",biography:"Samir El-Gendy is a Professor of anatomy and embryology at the faculty of veterinary medicine, Alexandria University, Egypt. Samir obtained his PhD in veterinary science in 2007 from the faculty of veterinary medicine, Alexandria University and has been a professor since 2017. Samir is an author on 24 articles at Scopus and 12 articles within local journals and 2 books/book chapters. His research focuses on applied anatomy, imaging techniques and computed tomography. Samir worked as a member of different local projects on E-learning and he is a board member of the African Association of Veterinary Anatomists and of anatomy societies and as an associated author at local and international journals. Orcid: https://orcid.org/0000-0002-6180-389X",institutionString:null,institution:{name:"Alexandria University",country:{name:"Egypt"}}},{id:"246149",title:"Dr.",name:"Valentina",middleName:null,surname:"Kubale",slug:"valentina-kubale",fullName:"Valentina Kubale",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/246149/images/system/246149.jpg",biography:"Valentina Kubale is Associate Professor of Veterinary Medicine at the Veterinary Faculty, University of Ljubljana, Slovenia. Since graduating from the Veterinary faculty she obtained her PhD in 2007, performed collaboration with the Department of Pharmacology, University of Copenhagen, Denmark. She continued as a post-doctoral fellow at the University of Copenhagen with a Lundbeck foundation fellowship. She is the editor of three books and author/coauthor of 23 articles in peer-reviewed scientific journals, 16 book chapters, and 68 communications at scientific congresses. Since 2008 she has been the Editor Assistant for the Slovenian Veterinary Research journal. She is a member of Slovenian Biochemical Society, The Endocrine Society, European Association of Veterinary Anatomists and Society for Laboratory Animals, where she is board member.",institutionString:"University of Ljubljana",institution:{name:"University of Ljubljana",country:{name:"Slovenia"}}},{id:"258334",title:"Dr.",name:"Carlos Eduardo",middleName:null,surname:"Fonseca-Alves",slug:"carlos-eduardo-fonseca-alves",fullName:"Carlos Eduardo Fonseca-Alves",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/258334/images/system/258334.jpg",biography:"Dr. Fonseca-Alves earned his DVM from Federal University of Goias – UFG in 2008. He completed an internship in small animal internal medicine at UPIS university in 2011, earned his MSc in 2013 and PhD in 2015 both in Veterinary Medicine at Sao Paulo State University – UNESP. Dr. Fonseca-Alves currently serves as an Assistant Professor at Paulista University – UNIP teaching small animal internal medicine.",institutionString:null,institution:{name:"Universidade Paulista",country:{name:"Brazil"}}},{id:"245306",title:"Dr.",name:"María Luz",middleName:null,surname:"Garcia Pardo",slug:"maria-luz-garcia-pardo",fullName:"María Luz Garcia Pardo",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/245306/images/system/245306.png",biography:"María de la Luz García Pardo is an agricultural engineer from Universitat Politècnica de València, Spain. She has a Ph.D. in Animal Genetics. Currently, she is a lecturer at the Agrofood Technology Department of Miguel Hernández University, Spain. Her research is focused on genetics and reproduction in rabbits. The major goal of her research is the genetics of litter size through novel methods such as selection by the environmental sensibility of litter size, with forays into the field of animal welfare by analysing the impact on the susceptibility to diseases and stress of the does. Details of her publications can be found at https://orcid.org/0000-0001-9504-8290.",institutionString:null,institution:{name:"Miguel Hernandez University",country:{name:"Spain"}}},{id:"350704",title:"M.Sc.",name:"Camila",middleName:"Silva Costa",surname:"Ferreira",slug:"camila-ferreira",fullName:"Camila Ferreira",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/350704/images/17280_n.jpg",biography:"Graduated in Veterinary Medicine at the Fluminense Federal University, specialist in Equine Reproduction at the Brazilian Veterinary Institute (IBVET) and Master in Clinical Veterinary Medicine and Animal Reproduction at the Fluminense Federal University. She has experience in analyzing zootechnical indices in dairy cattle and organizing events related to Veterinary Medicine through extension grants. I have experience in the field of diagnostic imaging and animal reproduction in veterinary medicine through monitoring and scientific initiation scholarships. I worked at the Equus Central Reproduction Equine located in Santo Antônio de Jesus – BA in the 2016/2017 breeding season. I am currently a doctoral student with a scholarship from CAPES of the Postgraduate Program in Veterinary Medicine (Pathology and Clinical Sciences) at the Federal Rural University of Rio de Janeiro (UFRRJ) with a research project with an emphasis on equine endometritis.",institutionString:null,institution:null},{id:"41319",title:"Prof.",name:"Lung-Kwang",middleName:null,surname:"Pan",slug:"lung-kwang-pan",fullName:"Lung-Kwang Pan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/41319/images/84_n.jpg",biography:null,institutionString:null,institution:null},{id:"125292",title:"Dr.",name:"Katy",middleName:null,surname:"Satué Ambrojo",slug:"katy-satue-ambrojo",fullName:"Katy Satué Ambrojo",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/125292/images/system/125292.jpeg",biography:"Katy Satué Ambrojo received her Veterinary Medicine degree, Master degree in Equine Technology and doctorate in Veterinary Medicine from the Faculty of Veterinary, CEU-Cardenal Herrera University in Valencia, Spain.Dr. Satué is accredited as a Private University Doctor Professor, Doctor Assistant, and Contracted Doctor by AVAP (Agència Valenciana d'Avaluació i Prospectiva) and currently, as a full professor by ANECA (since January 2022). To date, Katy has taught 22 years in the Department of Animal Medicine and Surgery at the CEU-Cardenal Herrera University in undergraduate courses in Veterinary Medicine (General Pathology, integrated into the Applied Basis of Veterinary Medicine module of the 2nd year, Clinical Equine I of 3rd year, and Equine Clinic II of 4th year). Dr. Satué research activity is in the field of Endocrinology, Hematology, Biochemistry, and Immunology in the Spanish Purebred mare. She has directed 5 Doctoral Theses and 5 Diplomas of Advanced Studies, and participated in 11 research projects as a collaborating researcher. She has written 2 books and 14 book chapters in international publishers related to the area, and 68 scientific publications in international journals. Dr. Satué has attended 63 congresses, participating with 132 communications in international congresses and 19 in national congresses related to the area. Dr. Satué is a scientific reviewer for various prestigious international journals such as Animals, American Journal of Obstetrics and Gynecology, Veterinary Clinical Pathology, Journal of Equine Veterinary Science, Reproduction in Domestic Animals, Research Veterinary Science, Brazilian Journal of Medical and Biological Research, Livestock Production Science and Theriogenology, among others. Since 2014 she has been responsible for the Clinical Analysis Laboratory of the CEU-Cardenal Herrera University Veterinary Clinical Hospital.",institutionString:null,institution:null},{id:"201721",title:"Dr.",name:"Beatrice",middleName:null,surname:"Funiciello",slug:"beatrice-funiciello",fullName:"Beatrice Funiciello",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/201721/images/11089_n.jpg",biography:"Graduated from the University of Milan in 2011, my post-graduate education included CertAVP modules mainly on equines (dermatology and internal medicine) and a few on small animal (dermatology and anaesthesia) at the University of Liverpool. After a general CertAVP (2015) I gained the designated Certificate in Veterinary Dermatology (2017) after taking the synoptic examination and then applied for the RCVS ADvanced Practitioner status. After that, I completed the Postgraduate Diploma in Veterinary Professional Studies at the University of Liverpool (2018). My main area of work is cross-species veterinary dermatology.",institutionString:null,institution:null},{id:"291226",title:"Dr.",name:"Monica",middleName:null,surname:"Cassel",slug:"monica-cassel",fullName:"Monica Cassel",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/291226/images/8232_n.jpg",biography:'Degree in Biological Sciences at the Federal University of Mato Grosso with scholarship for Scientific Initiation by FAPEMAT (2008/1) and CNPq (2008/2-2009/2): Project \\"Histological evidence of reproductive activity in lizards of the Manso region, Chapada dos Guimarães, Mato Grosso, Brazil\\". Master\\\'s degree in Ecology and Biodiversity Conservation at Federal University of Mato Grosso with a scholarship by CAPES/REUNI program: Project \\"Reproductive biology of Melanorivulus punctatus\\". PhD\\\'s degree in Science (Cell and Tissue Biology Area) \n at University of Sao Paulo with scholarship granted by FAPESP; Project \\"Development of morphofunctional changes in ovary of Astyanax altiparanae Garutti & Britski, 2000 (Teleostei, Characidae)\\". She has experience in Reproduction of vertebrates and Morphology, with emphasis in Cellular Biology and Histology. She is currently a teacher in the medium / technical level courses at IFMT-Alta Floresta, as well as in the Bachelor\\\'s degree in Animal Science and in the Bachelor\\\'s degree in Business.',institutionString:null,institution:null},{id:"442807",title:"Dr.",name:"Busani",middleName:null,surname:"Moyo",slug:"busani-moyo",fullName:"Busani Moyo",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Gwanda State University",country:{name:"Zimbabwe"}}},{id:"439435",title:"Dr.",name:"Feda S.",middleName:null,surname:"Aljaser",slug:"feda-s.-aljaser",fullName:"Feda S. Aljaser",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"King Saud University",country:{name:"Saudi Arabia"}}},{id:"423023",title:"Dr.",name:"Yosra",middleName:null,surname:"Soltan",slug:"yosra-soltan",fullName:"Yosra Soltan",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Alexandria University",country:{name:"Egypt"}}},{id:"349788",title:"Dr.",name:"Florencia Nery",middleName:null,surname:"Sompie",slug:"florencia-nery-sompie",fullName:"Florencia Nery Sompie",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Sam Ratulangi University",country:{name:"Indonesia"}}},{id:"428600",title:"MSc.",name:"Adriana",middleName:null,surname:"García-Alarcón",slug:"adriana-garcia-alarcon",fullName:"Adriana García-Alarcón",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"National Autonomous University of Mexico",country:{name:"Mexico"}}},{id:"428599",title:"MSc.",name:"Gabino",middleName:null,surname:"De La Rosa-Cruz",slug:"gabino-de-la-rosa-cruz",fullName:"Gabino De La Rosa-Cruz",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"National Autonomous University of Mexico",country:{name:"Mexico"}}},{id:"428601",title:"MSc.",name:"Juan Carlos",middleName:null,surname:"Campuzano-Caballero",slug:"juan-carlos-campuzano-caballero",fullName:"Juan Carlos Campuzano-Caballero",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"National Autonomous University of Mexico",country:{name:"Mexico"}}}]}},subseries:{item:{id:"7",type:"subseries",title:"Bioinformatics and Medical Informatics",keywords:"Biomedical Data, Drug Discovery, Clinical Diagnostics, Decoding Human Genome, AI in Personalized Medicine, Disease-prevention Strategies, Big Data Analysis in Medicine",scope:"Bioinformatics aims to help understand the functioning of the mechanisms of living organisms through the construction and use of quantitative tools. The applications of this research cover many related fields, such as biotechnology and medicine, where, for example, Bioinformatics contributes to faster drug design, DNA analysis in forensics, and DNA sequence analysis in the field of personalized medicine. Personalized medicine is a type of medical care in which treatment is customized individually for each patient. Personalized medicine enables more effective therapy, reduces the costs of therapy and clinical trials, and also minimizes the risk of side effects. Nevertheless, advances in personalized medicine would not have been possible without bioinformatics, which can analyze the human genome and other vast amounts of biomedical data, especially in genetics. The rapid growth of information technology enabled the development of new tools to decode human genomes, large-scale studies of genetic variations and medical informatics. The considerable development of technology, including the computing power of computers, is also conducive to the development of bioinformatics, including personalized medicine. In an era of rapidly growing data volumes and ever lower costs of generating, storing and computing data, personalized medicine holds great promises. Modern computational methods used as bioinformatics tools can integrate multi-scale, multi-modal and longitudinal patient data to create even more effective and safer therapy and disease prevention methods. Main aspects of the topic are: Applying bioinformatics in drug discovery and development; Bioinformatics in clinical diagnostics (genetic variants that act as markers for a condition or a disease); Blockchain and Artificial Intelligence/Machine Learning in personalized medicine; Customize disease-prevention strategies in personalized medicine; Big data analysis in personalized medicine; Translating stratification algorithms into clinical practice of personalized medicine.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/7.jpg",hasOnlineFirst:!0,hasPublishedBooks:!0,annualVolume:11403,editor:{id:"351533",title:"Dr.",name:"Slawomir",middleName:null,surname:"Wilczynski",slug:"slawomir-wilczynski",fullName:"Slawomir Wilczynski",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000035U1loQAC/Profile_Picture_1630074514792",biography:"Professor Sławomir Wilczyński, Head of the Chair of Department of Basic Biomedical Sciences, Faculty of Pharmaceutical Sciences, Medical University of Silesia in Katowice, Poland. His research interests are focused on modern imaging methods used in medicine and pharmacy, including in particular hyperspectral imaging, dynamic thermovision analysis, high-resolution ultrasound, as well as other techniques such as EPR, NMR and hemispheric directional reflectance. Author of over 100 scientific works, patents and industrial designs. Expert of the Polish National Center for Research and Development, Member of the Investment Committee in the Bridge Alfa NCBiR program, expert of the Polish Ministry of Funds and Regional Policy, Polish Medical Research Agency. 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Possible contributions can address (but are not limited to) the following research topics: Bioinspired design and control of exoskeletons, orthoses, and prostheses; Experimental evaluation of the effect of assistive devices (e.g., influence on gait, balance, and neuromuscular system); Bioinspired technologies for rehabilitation, including clinical studies reporting evaluations; Application of neuromuscular and biomechanical models to the development of bioinspired technology.',annualVolume:11404,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/8.jpg",editor:{id:"144937",title:"Prof.",name:"Adriano",middleName:"De Oliveira",surname:"Andrade",fullName:"Adriano Andrade",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRC8QQAW/Profile_Picture_1625219101815",institutionString:null,institution:{name:"Federal University of Uberlândia",institutionURL:null,country:{name:"Brazil"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"49517",title:"Prof.",name:"Hitoshi",middleName:null,surname:"Tsunashima",fullName:"Hitoshi Tsunashima",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYTP4QAO/Profile_Picture_1625819726528",institutionString:null,institution:{name:"Nihon University",institutionURL:null,country:{name:"Japan"}}},{id:"425354",title:"Dr.",name:"Marcus",middleName:"Fraga",surname:"Vieira",fullName:"Marcus Vieira",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00003BJSgIQAX/Profile_Picture_1627904687309",institutionString:null,institution:{name:"Universidade Federal de Goiás",institutionURL:null,country:{name:"Brazil"}}},{id:"196746",title:"Dr.",name:"Ramana",middleName:null,surname:"Vinjamuri",fullName:"Ramana Vinjamuri",profilePictureURL:"https://mts.intechopen.com/storage/users/196746/images/system/196746.jpeg",institutionString:"University of Maryland, Baltimore County",institution:{name:"University of Maryland, Baltimore County",institutionURL:null,country:{name:"United States of America"}}}]},{id:"9",title:"Biotechnology - Biosensors, Biomaterials and Tissue Engineering",keywords:"Biotechnology, Biosensors, Biomaterials, Tissue Engineering",scope:"The Biotechnology - Biosensors, Biomaterials and Tissue Engineering topic within the Biomedical Engineering Series aims to rapidly publish contributions on all aspects of biotechnology, biosensors, biomaterial and tissue engineering. We encourage the submission of manuscripts that provide novel and mechanistic insights that report significant advances in the fields. Topics can include but are not limited to: Biotechnology such as biotechnological products and process engineering; Biotechnologically relevant enzymes and proteins; Bioenergy and biofuels; Applied genetics and molecular biotechnology; Genomics, transcriptomics, proteomics; Applied microbial and cell physiology; Environmental biotechnology; Methods and protocols. Moreover, topics in biosensor technology, like sensors that incorporate enzymes, antibodies, nucleic acids, whole cells, tissues and organelles, and other biological or biologically inspired components will be considered, and topics exploring transducers, including those based on electrochemical and optical piezoelectric, thermal, magnetic, and micromechanical elements. Chapters exploring biomaterial approaches such as polymer synthesis and characterization, drug and gene vector design, biocompatibility, immunology and toxicology, and self-assembly at the nanoscale, are welcome. Finally, the tissue engineering subcategory will support topics such as the fundamentals of stem cells and progenitor cells and their proliferation, differentiation, bioreactors for three-dimensional culture and studies of phenotypic changes, stem and progenitor cells, both short and long term, ex vivo and in vivo implantation both in preclinical models and also in clinical trials.",annualVolume:11405,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/9.jpg",editor:{id:"126286",title:"Dr.",name:"Luis",middleName:"Jesús",surname:"Villarreal-Gómez",fullName:"Luis Villarreal-Gómez",profilePictureURL:"https://mts.intechopen.com/storage/users/126286/images/system/126286.jpg",institutionString:null,institution:{name:"Autonomous University of Baja California",institutionURL:null,country:{name:"Mexico"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"35539",title:"Dr.",name:"Cecilia",middleName:null,surname:"Cristea",fullName:"Cecilia Cristea",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYQ65QAG/Profile_Picture_1621007741527",institutionString:null,institution:{name:"Iuliu Hațieganu University of Medicine and Pharmacy",institutionURL:null,country:{name:"Romania"}}},{id:"40735",title:"Dr.",name:"Gil",middleName:"Alberto Batista",surname:"Gonçalves",fullName:"Gil Gonçalves",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYRLGQA4/Profile_Picture_1628492612759",institutionString:null,institution:{name:"University of Aveiro",institutionURL:null,country:{name:"Portugal"}}},{id:"211725",title:"Associate Prof.",name:"Johann F.",middleName:null,surname:"Osma",fullName:"Johann F. 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