T-norms and S-conorms.
\r\n\t
",isbn:"978-1-80356-273-5",printIsbn:"978-1-80356-272-8",pdfIsbn:"978-1-80356-274-2",doi:null,price:0,priceEur:0,priceUsd:0,slug:null,numberOfPages:0,isOpenForSubmission:!1,isSalesforceBook:!1,isNomenclature:!1,hash:"e1d9662c334dd78ab35bfb57c3bf106e",bookSignature:"Dr. Fabio Arturo Iannotti",publishedDate:null,coverURL:"https://cdn.intechopen.com/books/images_new/11675.jpg",keywords:"Skeletal Muscle Diseases, Rare Skeletal Muscle Diseases, Basic Research, Molecular Mechanisms of Disease, Translational Research, Diagnostic Technologies, Functional Tests, Disease Models, Innovative Therapies, Drug Repositioning, Drug Discovery, Emerging Technologies",numberOfDownloads:25,numberOfWosCitations:0,numberOfCrossrefCitations:0,numberOfDimensionsCitations:0,numberOfTotalCitations:0,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"February 11th 2022",dateEndSecondStepPublish:"April 19th 2022",dateEndThirdStepPublish:"June 18th 2022",dateEndFourthStepPublish:"September 6th 2022",dateEndFifthStepPublish:"November 5th 2022",dateConfirmationOfParticipation:null,remainingDaysToSecondStep:"2 months",secondStepPassed:!0,areRegistrationsClosed:!0,currentStepOfPublishingProcess:4,editedByType:null,kuFlag:!1,biosketch:"Dr. Fabio Arturo Iannotti received his Bachelor's Degree in Biotechnology Science at the University of Naples “Federico II” in 2006 with the highest degree. In 2010, he graduated with a Ph.D. in Neuroscience at the University of Naples “Federico II”. He published many papers on his areas of research in international peer-reviewed journals and for his pioneering studies has received awards from both national and international scientific societies.",coeditorOneBiosketch:null,coeditorTwoBiosketch:null,coeditorThreeBiosketch:null,coeditorFourBiosketch:null,coeditorFiveBiosketch:null,editors:[{id:"281317",title:"Dr.",name:"Fabio",middleName:"Arturo",surname:"Iannotti",slug:"fabio-iannotti",fullName:"Fabio Iannotti",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRdOdQAK/Profile_Picture_1644820016099",biography:"Currently researcher at the CNR-ICB Institute of Biomolecular Chemistry of Pozzuoli, Napoli (Italy), Fabio Arturo Iannotti has as major focus of his research activity the role of the endocannabinoid system and TRP in epilepsy and muscle development. Dr. Fabio Arturo Iannotti received his Bachelor Degree in Biotecnology Science (Medical curricula) at University of Naples \\'Federico II\\' in 2006 (with 110/110 cum laude). In 2010, Dr. Iannotti graduated with a PhD in Neuroscience at University of Naples \\'Federico II\\'. The focus of his thesis was on the role of voltage-gated potassium channels Kv7 during the neuronal excitoxicity as well as skeletal muscle cell differentiation. During the three years of the PhD program, Dr. Iannotti has been introduced to the field of ion channels, particularly voltage-gated ion channels; he has been instrumental in setting up RT-PCR and quantitative RT-PCR techniques in our lab, focusing onto research themes which would allow to combine both molecular and functional approaches in the study of ion channels during muscle cell differentiation. 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The systems for image recognition and classification have diverse applications, e.g. autonomous robot navigation[1], image tracking radar [2], face recognition [3], biometrics [4], intelligent transportation, license plate recognition, character recognition [5] and fingerprints [6].
\n\t\t\tThe problem of automatic image recognition is a composite task that involves detection and localization of objects in a cluttered background, segmentation, normalization, recognition and verification. Depending on the nature of the application, e.g. sizes of training and testing database, clutter and variability of the background, noise, occlusion, and finally, speed requirements, some of the subtasks could be very challenging. Assuming that segmentation and normalization haven been done, we focus on the subtask of object recognition and verification, and demonstrate the performance using several sets of images.
\n\t\t\tDiverse paradigms have been used in the development of algorithms for image recognition, some of them are: artificial neural networks [7, 8], principal component analysis [9, 10], fuzzy models [11, 12], genetic algorithms [13, 14] and Auto-Associative memory [15]. The following paragraphs describe some work done with these paradigms.
\n\t\t\tAbrishambaf
In [16], Yang and Park developed a fingerprint verification system based on a set of invariant moment features and a nonlinear Back Propagation Neural Network (BPNN) verifier. They used an image-based method with invariant moment features for fingerprint verification to overcome the demerits of traditional minutiae-based methods and other image-based methods. The proposed system contains two stages: an off-line stage for template processing and an on-line stage for testing with input fingerprints. The system preprocesses fingerprints and reliably detects a unique reference point to determine a Region of Interest (ROI). A total of four sets of seven invariant moment features are extracted from four partitioned sub-images of an ROI. Matching between the feature vectors of a test fingerprint and those of a template fingerprint in the database is evaluated by a nonlinear BPNN and its performance is compared with other methods in terms of absolute distance as a similarity measure. The experimental results show that the proposed method with BPNN matching has a higher matching accuracy, while the method with absolute distance has a faster matching speed. Comparison results with other famous methods also show that the proposed method outperforms them in verification accuracy.
\n\t\t\tIn [17] the authors presents a classifier based on Radial Basis Function Network (RBFN) to detect frontal views of faces. The technique is separated into three main steps, namely: preprocessing, feature extraction, classification and recognition. The curvelet transform, Linear Discriminant Analysis (LDA) are used to extract features from facial images first, and RBFN is used to classify the facial images based on features. The use of RBFN also reduces the number of misclassification caused by not-linearly separable classes. 200 images are taken from ORL database and the parameters like recognition rate, acceptance ratio and execution time performance are calculated. It is shown that neural network based face recognition is robust and has better performance of recognition rate 98.6% and acceptance ratio 85 %.
\n\t\t\tBhowmik
Zeng and Liu described state of the art of important advances of type-2 fuzzy sets for pattern recognition [18]. The success of type-2 fuzzy sets has been largely attributed to their three-dimensional membership functions to handle more uncertainties in real-world problems. In pattern recognition, both feature and hypothesis spaces have uncertainties, which motivate us of integrating type-2 fuzzy sets with conventional classifiers to achieve a better performance in terms of the robustness, generalization ability, or recognition accuracy.
\n\t\t\tA face recognition system for personal identification and verification using Genetic algorithm (GA) and Back-propagation Neural Network (BPNN) is described in [19]. The system consists of three steps. At the very outset some pre-processing are applied on the input image. Secondly face features are extracted, which will be taken as the input of the Back-propagation Neural Network and Genetic Algorithm in the third step and classification is carried out by using BPNN and GA. The proposed approaches are tested on a number of face images. Experimental results demonstrate the higher degree performance of these algorithms.
\n\t\t\tIn [20], Blahuta
Pandit and Gupta proposed a Neural Network model that has been utilized to train the system for image recognition. The NN model uses Auto-Associative memory for training. The model reads the image in the form of a matrix, evaluates the weight matrix associated with the image. After training process is done, whenever the image is provided to the system the model recognizes it appropriately. The evaluated weight matrix is used for image pattern matching. It is noticed that the model developed is accurate enough to recognize the image even if the image is distorted or some portion/ data is missing from the image. This model eliminates the long time consuming process of image recognition [15].
\n\t\t\tIn [21], authors present the design of three types of neural networks with different features for image recognition, including traditional backpropagation networks, radial basis function networks and counterpropagation networks. The design complexity and generalization ability of the three types of neural network architectures are tested and compared based on the applied digit image recognition problem. Traditional backpropagation networks require very complex training process before being applied for classification or approximation. Radial basis function networks simplify the training process by the specially organized 3-layer architecture. Counterpropagation networks do not need training process at all and can be designed directly by extracting all the parameters from input data. The experimental results show the good noise tolerance of both RBF networks and counterpropagation network on the image recognition problem, and somehow point out the poor generalization ability of traditional backpropagation networks. The excellent noise rejection ability makes the RBF networks very proper for image data preprocessing before applied for recognition.
\n\t\t\tThe remaining sections of this Chapter are organized as follows. In next Section, a brief theoretical background of the Learning Algorithm for Multivariate Data Analysis (LAMDA) is given. In Section 3 we describe the proposed search algorithm for image recognition based on LAMDA algorithm. Then, in Section 4 we present the implementation results obtained by the proposed approach. Finally, Section 5 contains the conclusions of this Chapter.
\n\t\tThe Learning Algorithm for Multivariate Data Analysis (LAMDA) is an incremental conceptual clustering method based on fuzzy logic, which can be applied in the processes of formation and recognition of concepts (classes). LAMDA has the following features [22-24]:
\n\t\t\tThe previous knowledge of the number of classes is not necessary (unsupervised learning).
The descriptors can be qualitative, quantitative or a combination of both.
LAMDA can use a supervised learning stage followed by unsupervised one; for this reason, it is possible to achieve an evolutionary classification.
Formation and recognition of concepts are based on the maximum adequacy (MA) rule.
This methodology has the possibility to control the selectivity of the classification (exigency level) through the parameter\n\t\t\t\t\t\t\t
LAMDA models the concept of maximum entropy (homogeneity). This concept is represented by a class denominated Non-Informative Class (NIC). The NIC concept plays the role of a threshold of decision, in the concepts formation process.
Traditionally, the concept of similarity between objects has been considered fundamental to determine whether the descriptors are members of a class or not. LAMDA does not uses similarity measures between objects in order to group them, but it calculates a degree of adequacy. This concept is expressed as a membership function between the descriptor and any of the previously established classes [22, 25].
\n\t\t\tThe objects \n\t\t\t\t\t\t
The set of objects can be described by \n\t\t\t\t\t\t
Given an object \n\t\t\t\t\t\t\t
Hence, one MAD vector can be associated with an object \n\t\t\t\t\t\t\t
LAMDA basic structure.
Membership functions, denoted as\n\t\t\t\t\t\t\t
A membership function must be bounded from below\n\t\t\t\t\t\t\t\t\t
The range of a membership function must therefore be [0, 1].
For each\n\t\t\t\t\t\t\t\t\t
The MAD is a membership function derived from a fuzzy generalization of a binomial probability law [26]. As before, \n\t\t\t\t\t\t\t
where\n\t\t\t\t\t\t\t
Fuzzy Binomial Distribution.
Fuzzy Binomial-Center Distribution.
Fuzzy Binomial-Distance Distribution.
Gaussian Distribution.
Global Adequacy degree (GAD) is obtained by aggregating or summarizing of all marginal information previously calculated (see Figure 1), using mathematical aggregation operators (T-norms and S-conorms) given
The aggregation operators are mathematical objects that have the function of reducing a set of numbers into a unique representative number. This is simply a function, which assigns a real number \n\t\t\t\t\t\t\t
The T-norms and S-conorms are two families specialized on the aggregation under uncertainty. They can also be seen as a generalization of the Boolean logic connectives to multi-valued logic. The T-norms generalize the conjunctive \'AND\' (intersection) operator and the S-conorms generalize the disjunctive \'OR\' (union) operator [30].
\n\t\t\t\t\tLinear convex T-S function is part of the so-called compensatory functions, and is utilized to combine a T-norm and a S-conorm in order to compensate their opposite effects. Zimmermann and Zysno [30] discovered that in a decision making context humans neither follow exactly the behavior of a T-norm nor a S-conorm when aggregating. In order to get closer to the human aggregation process, they proposed an operator on the unit interval based on T-norms and S-conorms.
\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t
Min-Max | \n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t
Product | \n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t
Lukasiewicz | \n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t
Yaguer | \n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t
Hammacher | \n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t \n\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t \n\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t
T-norms and S-conorms.
One class of non-associative T-norm and T-conorm-based compensatory operator is the linear convex T-S function [31]:
\n\t\t\t\t\twhere\n\t\t\t\t\t\t\t
Finally, once computed the GAD of the object \n\t\t\t\t\t\t\t
LAMDA has been applied to different domains: medical images [32], pattern recognition [33], detection and diagnosis of failures of industrial processes [34], biological processes [35], distribution systems of electrical energy [36], processes for drinking water production [29], monitoring and diagnosis of industrial processes [37], selection of sensors [38], vector quantization [39].
\n\t\t\t\tIn this section the image recognition algorithm based on LAMDA is described. Our proposal is divided into two phases, training and recognition. At training phase, a codebook is generated based on LAMDA algorithm, let us name it LAMDA codebook. At recognition phase, we propose a search algorithm based on LAMDA and we show its application in image recognition process.
\n\t\t\tThe LAMDA codebook is calculated in two stages, see Figure 2.
\n\t\t\t\tLAMDA codebook generation scheme
Stage 1.
Let \n\t\t\t\t\t\t
Stage 2.
where\n\t\t\t\t\t\t
The proposed search algorithm performs the recognition task according to a membership criterion, computed in four stages.
\n\t\t\t\tStage 1.
where\n\t\t\t\t\t\t
Stage 2.
\n\t\t\t\t\t
where\n\t\t\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t\t\t
where\n\t\t\t\t\t\t
\n\t\t\t\t\t
where \n\t\t\t\t\t\t
Stage 3.
\n\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t
Min-Max | \n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t
Product | \n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t
Mathematical aggregation operators
Stage 4.
\n\t\t\t\t\tFigure 3 shows the proposed VQ scheme that makes use of the LAMDA algorithm and the codebook generated by LAMDA algorithm.
\n\t\t\t\tSearch algorithm LAMDA
In this section, the findings of the implementation of the search algorithm LAMDA, in image recognition of gray-scale are presented. In this implementation the fuzzy probability distributions, binomial and binomial center, and the aggregation operators, product and min-max are only used because only they have a lower computational complexity.
\n\t\t\tImages of set-1, (a) original image. Altered images, erosive noise (b) 60%, (c) 100%; mixed noise (d) 30 %, (e) 40%
Images of set-2, (a) original image. Altered images, erosive noise (b) 60%, (c) 100%; mixed noise (d) 30 %, (e) 40%
For this experiment we chose two test sets of images, called set-1 and set-2, and their altered versions (see Figures 4, 5). We say that an altered version \n\t\t\t\t\t
To evaluate the proposed search algorithm performance, altered versions of these images distorted by random noise were presented to the classification stage of the search algorithm LAMDA (see Figures 4, 5).
\n\t\t\t\n\t\t\tThe fact of using two fuzzy probability distributions and two aggregation operators allows four combinations. This way, four versions of the search algorithm LAMDA are obtained: binomial min-max, binomial product, binomial center min-max and binomial center product. Moreover, we proceeded to modify it in the range from 0 to 1 with step 0.1 to determine the value of the level of exigency (α) that provide the best results. Each version of LAMDA was evaluated using two sets of test images. The results of this experiment are shown in Tables 3 and 4.
\n\t\t\t\n\t\t\t\tTable 3 shows the results obtained using the combinations: binomial min-max, binomial product, binomial center min-max y binomial center product and using the set of test images of the set-1.
\n\t\t\t\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\n\t\t\t\t\t\t\t | \n\t\t\t\t\t|||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\n\t\t\t\t\t\t\t | \n\t\t\t\t\t|||||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\n\t\t\t\t\t\t\t | \n\t\t\t\t\t|||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\tBinomial | \n\t\t\t\t\t\tMin-max | \n\t\t\t\t\t\t1 | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t|||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\tBinomial | \n\t\t\t\t\t\tProduct | \n\t\t\t\t\t\t0-1 | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t|||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\tBinomial center | \n\t\t\t\t\t\tMin-max | \n\t\t\t\t\t\t1 | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t|||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\tBinomial center | \n\t\t\t\t\t\tProduct | \n\t\t\t\t\t\t1 | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t|||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t
Performance results (recognition rate) showed by the proposed search algorithm withaltered versions of the test images of set-1
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\n\t\t\t\t\t\t\t | \n\t\t\t\t\t|||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\n\t\t\t\t\t\t\t | \n\t\t\t\t\t|||||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\n\t\t\t\t\t\t\t | \n\t\t\t\t\t|||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\tBinomial | \n\t\t\t\t\t\tMin-max | \n\t\t\t\t\t\t1 | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t|||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\tBinomial | \n\t\t\t\t\t\tProduct | \n\t\t\t\t\t\t1 | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t|||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\tBinomial center | \n\t\t\t\t\t\tMin-max | \n\t\t\t\t\t\t1 | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t|||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\tBinomial center | \n\t\t\t\t\t\tProduct | \n\t\t\t\t\t\t1 | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t\t100% | \n\t\t\t\t\t|||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t||||||
\n\t\t\t\t\t\t\t | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t\t0% | \n\t\t\t\t\t
Performance results (recognition rate) showed by the proposed search algorithm withaltered versions of the test images of set-2 .
In the case of the combination of the binomial distribution with the aggregation operator min-max, the best results were obtained with a value of exigency level in the range from 0.8 to 1. We chose the exigency level equal to 1. As a result, the linear convex function is reduced by half, and, consequently, the number of operations is reduced. On the other hand, the combination of the binomial distribution with the aggregation operator product was unable to perform the classification.
\n\t\t\tIn the combination of the binomial center distribution with the aggregation operator min-max, the best results were obtained with a value of exigency level in the range from 0.1 to 1. We chose the exigency level equal to 1. This way, the linear convex function is reduced by half thus reducing the number of operations.
\n\t\t\tOn the other hand, using the combination of the binomial center distribution with the aggregation operator product, the best results were obtained with a value of exigency level equal to 1. Although, as it is shown in Table 3, the classification is not efficient with the images altered with erosive noise of 100% and with mixed noise of 30% and 40%. With this combination, the best results were obtained in comparison to the combination of the binomial distribution with the aggregation operator product.
\n\t\t\t\n\t\t\t\tTable 4 show the results obtained using the combinations: binomial min-max, binomial product, binomial center min-max and binomial center product and using the set of test images of the set-2.
\n\t\t\tFor the combination of the binomial distribution with the aggregation operator min-max, the best results were obtained with a value of exigency level in the range from 0.7 to 1. With the exigency level equal to 1, the linear convex function is reduced by half thus reducing the number of operations. On the other hand, the combination of the binomial distribution with the aggregation operator product was unable to perform classification.
\n\t\t\tIn the combination of the binomial center distribution with the aggregation operator min-max, the best results were obtained with a value of exigency level in the range from 0.1 to 1. Choosing the exigency level equal to 1, the linear convex function is reduced by half and the number of operations is reduced too. On the other hand, the combination of the binomial center distribution with the aggregation operator product was unable to perform classification.
\n\t\tIn this Chapter, we have proposed the use of LAMDA methodology as a search algorithm for image recognition. It is important to mention that we used LAMDA algorithm both in the training phase and in the recognition phase.
\n\t\t\tThe advantage of the LAMDA algorithm is its versatility which allows obtaining different versions making the combination of fuzzy probability distributions and aggregation operators. Furthermore, it also has the possibility to vary the exigency level, and we can locate the range or the value of the exigency level where the algorithm has better results.
\n\t\t\tAs it was shown in Tables 3 and 4, the search algorithm is competitive, since acceptable results were obtained in the combinations: binomial min-max, binomial center min-max with both sets of images. As you can see the product aggregation operator was not able to perform the recognition. In both combinations the exigency level was equal to 1, this fact allowed to reduce the linear convex function.
\n\t\t\tFinally, from these two combinations it is better to choose the binomial min-max, because with this combination fewer operations are performed.
\n\t\tThe important role of the livestock sector in food security is well understood [1]. At the same time, the sector plays a significant role in greenhouse gas emissions to the atmosphere [2, 3]. Among total agriculture sector emissions (5.4 Gt CO2e), 60% is due to livestock emission sources, mostly (63%) enteric fermentation [4].
Within the United Nations Framework Convention on Climate Change (UNFCCC), developing countries are presently required to submit national GHG inventory reports through National Communications. These reports are to be prepared following the Intergovernmental Panel on Climate Change (IPCC) Guidelines for GHG inventories [5]. The 2006 IPCC Guidelines set out three levels (or tiers) of increasing complexity (called Tiers 1–3) for use by a country. The purpose of the tiers is to provide unbiased and accurate estimates of national GHG emissions, and to enable inventory compilers to focus the use of resources on improving accuracy for key emission categories in the inventory. The Tier 1 method provides default values for GHG emissions per head of livestock and can reflect only variation in livestock numbers. The IPCC 2006 Tier 2 method for estimating enteric fermentation emissions from ruminants is based on net energy estimated using the National Research Council model [6]. This approach requires details on the characteristics of livestock sub-categories and their performance, for example, in terms of production (e.g., milk yield, daily weight gain) and reproduction (e.g., percentage of lactating cows).
At present, due to the scarcity of appropriate information on agricultural production in Sub-Saharan Africa (SSA), most countries in this region use the Tier 1 approach to quantify agricultural GHG emissions [7]. However, adopting the IPCC Tier 2 methodology can increase the accuracy of emission estimates [8]. In the SSA region [9, 10], provide enteric methane emission factors (EF) for cattle in South Africa and Benin, respectively, using the Tier 2 approach. A Tier 2 inventory for dairy cattle has also been produced by Kenya [11]. Since its second national communication in 2010, Senegal’s national GHG inventory, prepared by the Ministry of Environment, has used EFs calculated using a Tier 2 approach.
However, caution is required when applying the IPCC Tier 2 method to livestock systems in Africa. A recent study reported that the Tier 2 model had low predictive ability when the quality of diet changes [12]. In addition, estimation of enteric methane through the IPCC Tier 2 model assumes that animal is reared in ad libitum conditions throughout the year. In extensive livestock systems such as in West Africa, feedstuffs from grazing resources are typically available in the wet season but is very scarce during the dry season [13, 14, 15].
In recent years, further methods have been developed which allow highly accurate determination of emissions [16, 17, 18]. However, for developing countries, these measurement techniques may be very expensive and require significant knowledge to implement [19, 20]. Despite its possible shortcomings, therefore, the 2006 IPCC Tier 2 method is a practical method to estimate enteric methane emissions from cattle with greater accuracy than the default Tier 1 method [5].
Implementing a detailed uncertainty and sensitivity analysis of the input parameters in the IPCC Tier 2 model can provide guidance for targeting future research efforts to improve enteric fermentation estimates, with which to inform national GHG inventories, Nationally Appropriate Mitigation Actions (NAMAs) and Nationally Determined Contributions (NDCs).
In this study, the first objective is to use uncertainty analysis (UA) to identify which input parameters contribute significantly to the overall uncertainty of enteric methane emission factors estimated using the IPCC Tier 2 model. The second purpose is to apply sensitivity analysis (SA) in order to identify which parameters, need additional research, thereby increasing the accuracy of enteric methane emission factors.
Senegal is the most westerly country in Africa with a tropical climate. It covers a surface area of 196,712 square kilometers and has an estimated population of 15.7 million [21]. Approximately 77% of the working population are employed in the agricultural sector [22]. According to the latest population estimates for the year 2018, the rural population represents about 53% of the total population [21]. The estimated ruminant livestock numbers provided by the Senegalese Ministry of Livestock and Animal Production (MEPA) are 3.6 million cattle, 6.7 million sheep and 5.7 million goats [23].
Extensive livestock farming systems in Senegal are based on two native cattle breeds which are found in different agroecological zones. The zebu Gobra (
Our evaluation was implemented using the Tier 2 model recommended by IPCC [5]. This model (Eq. (1)) allows to approximate enteric methane emission factors (MEF, kg CH4/head/year) which is the output variable. To calculate gross energy intake (GE, MJ/d), net energy (NE, MJ/d) needed for different metabolic functions (i.e., maintenance, activity, growth, lactation, work and pregnancy) was predicted for each cattle subcategory using various formulas presented in the IPCC Guidelines. The output variable is calculated based on input parameters, such as average live body weight (LW, kg), average daily weight gain (ADG, kg/day), milk production (Milk, kg/day), feeding situation, and digestible energy (DE, %). Finally, these parameters together with the methane (CH4) conversion factor (Ym, %) enable calculation of net energy (NE, MJ/day), average daily feed intake (in terms of gross energy content, MJ/d) and the MEF (i.e., output) for each animal sub-category.
where:
EF = emission factor, kg CH4 head/yr,
GE = gross energy intake, MJ head/yr,
Ym = methane conversion factor, per cent of gross energy in feed converted to methane.
The factor 55.65, (MJ/kg CH4) is the energy content of methane.
The data for input parameters used derived mainly from two Livestock Research Centres (LRC) of the Senegalese Agricultural Research Institute (Institut Sénégalais de Recherches Agricoles, ISRA, see www.isra.sn): the Centre de Recherches Zootechniques de Dahra (CRZ-D) and the Centre de Recherches Zootechniques de Kolda (CRZ-K). These LRCs are located in the Ferlo and the Casamance areas, respectively. The general focus of these LRCs is to disseminate bulls to Senegalese family farms, so as to maintain and improve the productivity (milk and meat) of indigenous cattle. CRZ-D and CRZ-K frequently collect data on reproductive (e.g., rank of calving, calving interval) and productive (e.g., LW, ADG, Milk) performance through surveys and direct measurements implemented as part of research programs conducted independently or in partnership with international research organizations (e.g., CIRAD, FAO).
For this study, research reports, theses, publications and data sourced from ISRA databases (http://intranet.isra.sn/aurifere/opac_css/) were examined for relevant information. Documents (e.g., annual reports) from the Senegalese Livestock Ministry (MEPA, http://www.elevage.gouv.sn/) and the National Agency for Statistics and Demography (ANSD, http://www.ansd.sn) were also consulted. When country-specific data was not available, values from the 2006 IPCC Guidelines for National Greenhouse Gas Inventories was used. Table 1 presents the data sources used to estimate emission factors for Senegalese cattle breeds.
Parameters | Symbol | Unit | References | |
---|---|---|---|---|
Gobra cattle | Ndama cattle | |||
Coefficient for calculating Net energy for maintenance | Cfi | MJ/d/kg | [5] | |
Activity coefficient corresponding to animal’s feed situation | Ca | MJ/d/kg | [5] | |
Average live body weight | LW | Kg | CRZ-D database | CRZ-K database |
Mature live body weight | MW | Kg | From expert opinion | From expert opinion |
Average daily weight gain | ADG | kg/d | [26, 27, 28] | CRZ-K Research reports |
Coefficient | C | dim. | [5] | |
Average daily milk yield | Milk | kg/d | [24] | CRZ-K Research reports |
Fat content of milk | Fat | % | [29] | CRZ-K Research reports |
Number of hours of work | Hour | H | CRZ-D research reports | CRZ-K research reports |
Pregnancy coefficient | Cp | dim. | [5] | |
Methane conversion rates | Ym | % | [5] | |
Feed Digestibility | DE | % | [5] |
Input parameters used to estimate enteric methane emission factors for Gobra and Ndama cattle using the Tier 2 methodology and their sources.
d: day; dim.: dimensionless; CRZ-D: Centre de Recherches Zootechniques de Dahra; CRZ-K: Centre de Recherches Zootechniques de Kolda.
Authors from many scientific fields have described the application of uncertainty analysis (UA) and sensitivity analysis (SA) procedures to various modeling situations [30, 31, 32] and for a number of purposes [33]. For example, to achieve comprehensive uncertainty analysis, the 2006 IPCC Guidelines [5] recommend to use the Monte Carlo (MC) simulation method. The MC methodology is useful for dealing with great uncertainties, complex models and existing correlations between parameters [34, 35]. However, expanding the MC domain increases the requirements of the user, in terms of acquiring additional data and designing the analysis, and thus requires strong collaboration between experts [36]. For this present study, analysis of variance (ANOVA) and the standardized regression coefficient (SRC) were implemented for UA and SA, respectively.
Analysis was applied to emission factors for lactating cows (LC) and adult males (MA). The latest national communication indicates that these two animal classes are the largest emission sources among all cattle categories in Senegal [37]. For each of these animal categories, only the relevant parameters were estimated. For example, parameters such as milk yield (Milk, kg/day), fat content of milk (Fat, %) and the coefficient for pregnancy (Cp) were not estimated for MA, while number of hours of work (Hour, h/day) was not estimated for LC. Hence, 11 and 9 input parameters were considered for LC and MA, respectively. The number of simulations were 200,000 and 20,000 for LC and MA, respectively. These numbers were assumed to be satisfactory to stabilize the output. Indeed, a 3-level complete factorial design was defined [38] and considering the K dichotomous input parameters, the design requires 3 K simulations, i.e., 311 and 39 combinations of values for LC and MA, respectively [39].
Uncertainty analysis (UA) was applied to the enteric methane emission factors (MEF) of Senegalese native cattle derived using the IPCC Tier 2 method.
The input parameters characterized were from two main sources, i.e., parameters with values proposed by the 2006 IPCC Guidelines (PM) and parameters specific to extensive livestock farming systems in Senegal (PS).
The uncertainties of PM expressed in this study were those taken from the literature [5, 40]. The uncertainties of PS were not defined in the Senegalese NIR. Therefore, expert judgment was used to characterize the uncertainty of each PS. To do this, we proceeded as follows. The average value of each PS was estimated using livestock data reported from research conducted in Senegal. Then, these values were shared with national experts for assessment. These national specialists, who had worked previously on countrywide livestock research programs, suggested standard deviations around each mean values of PS, and these were used to represent relative uncertainties of each PS.
Consequently, an uncertainty of ±15% around the value of average live weight (LW, kg) and average daily gain (ADG, kg/day) were assumed. The fitted values of mature weight (MW, kg) had a relative uncertainty of ±25%. Milk production per lactating cow (Milk, kg/day) reported from the extensive livestock farming systems varies widely within and between Senegalese traditional farms, so an uncertainty range of ±20% was assumed, while the value of fat content of milk (Fat, %) was set to randomly fluctuate by ±2%. Regarding feed digestibility (DE, %), an uncertainty of ±15% is most commonly reported in the literature [40, 41, 42]. For this study, a value of ±20% was recommended by Senegalese experts, considering the extensive livestock farming systems, which are largely based on the use of rangeland forage resources. The probability density functions (PDFs) of all used input parameters is believed to be symmetrical.
The overall uncertainty in the estimated output is assumed to be normally distributed, with a 95% confidence interval of plus or minus the uncertainty of the assigned value for each input parameter. The Tables 2 and 3 list the used values of the input parameters, for each breed and animal category.
Symbol1 | Unit | Used value2 | Uncertainty (±%) | Sources of used uncertainties | |
---|---|---|---|---|---|
Gobra | Ndama | ||||
ADG | kg/day | 0.135 | 0.110 | 15 | Expert opinion |
C | dimensionless | 0.8 | 0.8 | 30 | [40] |
Ca | MJ/day/kg | 0.36 | 0.36 | 30 | [40] |
Cfi | MJ/day/kg | 0.386 | 0.386 | 30 | [40] |
Cp | dimensionless | 0.10 | 0.10 | 10 | [40] |
DE | % | 50 | 50 | 20 | Expert opinion |
Fat | % | 4.7 | 4.24 | 2 | Expert opinion |
LW | kg | 250 | 200 | 15 | Expert opinion |
Milk | kg/day | 0.922 | 0.870 | 20 | Expert opinion |
MW | kg | 200 | 180 | 25 | Expert opinion |
Ym | % | 6.5 | 6.5 | 15 | [5] |
Symbol1 | Unit | Used value2 | Uncertainty (±%) | Sources of used uncertainties | |
---|---|---|---|---|---|
Gobra | Ndama | ||||
ADG | kg/day | 0.135 | 0.110 | 15 | Expert opinion |
C | dimensionless | 1.2 | 1.2 | 30 | [40] |
Ca | MJ/day/kg | 0.36 | 0.36 | 30 | [40] |
Cfi | MJ/day/kg | 0.37 | 0.37 | 30 | [40] |
DE | % | 50 | 50 | 20 | Expert opinion |
Hour | h/day | 1.23 | 1.23 | 10 | Expert opinion |
LW | kg | 300 | 250 | 15 | Expert opinion |
MW | kg | 200 | 180 | 25 | Expert opinion |
Ym | % | 6.5 | 6.5 | 15 | [5] |
To estimate the specific contribution of each parameter to overall uncertainty (i.e., uncertainty associated with calculation of enteric methane emission factors), the analysis of variance (ANOVA) procedure was applied. To do this, the uncertainty ranges related to the input parameters were used to define the maximum and minimum values of each input parameter. The distributions were defined as uniform (i.e., normal distributions). Then, using the “runif” instruction, input parameter values were randomly generated using R software [43]. To mimic the contributions of the generated values of each input parameter to output uncertainty, the equations proposed by the IPCC [5] were used. To rank the input parameters according to their effect on the output, the sums of the squares (Sum Sq) computed by the ANOVA procedure for each input parameter were divided by the total sums of squares. Therefore, the results were expressed as a proportion and ordered in terms of percentage contribution to output uncertainty, using the instruction order in the R software. The total uncertainty of enteric methane emission factors was calculated using Rule A [5], which is approximation approach based on first-order Taylor series expansion, often referred to as error propagations [44].
Some of the SA approach used in this study has been presented previously as a case study (see https://www.agmrv.org) for the Livestock Research Group of the Global Research Alliance for Agricultural Greenhouse Gases (https://globalresearchalliance.org).
A sensitivity package developed by [45] and implemented in R software was used to conduct a global sensitivity analysis procedure [46]. First, to generate values between a minimum and the maximum, we set a range of variation of ±20% around the allocated value of each input parameter, assuming a uniform distribution (with a 95% confidence interval). Second, these values were input into the 2006 IPCC Tier 2 model to generate a range of values for the output. Finally, the standardized regression coefficient (SRC) was used to obtain sensitivity indices for each input parameter [47]. The SRC reflects the change in the standard deviation of the MEF when all other input parameters are fixed and unchanged [48, 49].
The estimated values of the effect of each input parameter on overall uncertainty are presented in Tables 4 and 5 for lactating cows and adult males of the Gobra and Ndama cattle breeds, respectively.
Species | Parameters | Sum sq | Mean sq | F value | Pr (>F) | Contribution (%) |
---|---|---|---|---|---|---|
Gobra | Cfi | 6302301 | 6302301 | 7319021 | 0.000 | 58.2 |
DE | 2064336 | 2064336 | 2397366 | 0.000 | 19.1 | |
Ym | 1823864 | 1823864 | 2118099 | 0.000 | 16.8 | |
Ca | 350673 | 350673 | 407245 | 0.000 | 3.2 | |
LW | 96244 | 96244 | 111770 | 0.000 | 0.9 | |
Milk | 20210 | 20210 | 23470 | 0.000 | 0.2 | |
Cp | 3330 | 3330 | 3867 | 0.000 | 0.0 | |
ADG | 109 | 109 | 127 | 0.000 | 0.0 | |
Fat | 83 | 83 | 96 | 0.000 | 0.0 | |
C | 66 | 66 | 77 | 0.000 | 0.0 | |
MW | 16 | 16 | 18 | 0.000 | 0.0 | |
Residuals | 172207 | 1 | NA | NA | 1.6 | |
Ndama | Cfi | 4509591 | 4509591 | 6005876 | 0.000 | 54.4 |
DE | 1438224 | 1438224 | 1915428 | 0.000 | 17.3 | |
Ym | 1293936 | 1293936 | 1723265 | 0.000 | 15.6 | |
LW | 625802 | 625802 | 833444 | 0.000 | 7.5 | |
Ca | 253737 | 253737 | 337927 | 0.000 | 3.1 | |
Milk | 15579 | 15579 | 20748 | 0.000 | 0.2 | |
Cp | 2938 | 2938 | 3913 | 0.000 | 0.0 | |
Fat | 119 | 119 | 158 | 0.000 | 0.0 | |
MW | 72 | 72 | 95 | 0.000 | 0.0 | |
C | 68 | 68 | 90 | 0.000 | 0.0 | |
ADG | 0 | 0 | 0 | 0.659 | 0.0 | |
Residuals | 150164 | 1 | NA | NA | 1.8 |
Contribution to the overall uncertainty of input parameters used to calculate enteric methane emission factors for lactating cows of Senegalese native cattle breeds.
NA: not applicable.
Species | Parameters | Sum sq | Mean sq | F value | Pr (>F) | Contribution (%) |
---|---|---|---|---|---|---|
Gobra | Cfi | 760631 | 760631 | 605099 | 0.000 | 56.3 |
DE | 216733 | 216733 | 172416 | 0.000 | 16.0 | |
Ym | 195408 | 195408 | 155451 | 0.000 | 14.5 | |
LW | 107049 | 107049 | 85160 | 0.000 | 7.9 | |
Ca | 46181 | 46181 | 36738 | 0.000 | 3.4 | |
Hour | 646 | 646 | 514 | 0.000 | 0.0 | |
ADG | 8 | 8 | 6 | 0.014 | 0.0 | |
C | 2 | 2 | 1 | 0.241 | 0.0 | |
MW | 0 | 0 | 0 | 0.536 | 0.0 | |
Residuals | 25128 | 1 | NA | NA | 1.9 | |
Ndama | Cfi | 595693 | 595693 | 611755 | 0.000 | 57.0 |
DE | 161026 | 161026 | 165368 | 0.000 | 15.4 | |
Ym | 148597 | 148597 | 152604 | 0.000 | 14.2 | |
LW | 82999 | 82999 | 85237 | 0.000 | 7.9 | |
Ca | 37722 | 37722 | 38739 | 0.000 | 3.6 | |
Hour | 276 | 276 | 284 | 0.000 | 0.0 | |
MW | 14 | 14 | 15 | 0.000 | 0.0 | |
C | 1 | 1 | 1 | 0.273 | 0.0 | |
ADG | 0 | 0 | 0 | 0.746 | 0.0 | |
Residuals | 19465 | 1 | NA | NA | 1.9 |
Contribution to the overall uncertainty of input parameters used to calculate enteric methane emission factors for adult male Senegalese native cattle breeds.
NA: not applicable.
The results show the effect of broad differences in the values for input parameters used in terms of their influence (expressed as a percentage, %) on overall uncertainty. The coefficient for maintenance (Cfi) contributes more than 55% of the overall uncertainty. Digestibility (DE) and the methane conversion factor (Ym) were the second and third most significant input parameters, respectively. The contributions of the other parameters were less than 10%.
In general, these results were similar for each animal sub-category of each breed, although there was some difference in terms of the contribution of these parameters to overall uncertainty. For example, with respect to lactating cows, the effect of Cfi on the total uncertainty of the enteric methane EF calculation was greater for Gobra (58.2%) compared to Ndama (54.4%). By comparison, the contribution of Cfi for adult males was 57.0% and 56.3% for Ndama and Gobra, respectively.
Figures 1 and 2 show the standardized regression coefficients (SRC) of each input parameter used to evaluate the enteric methane emission factors for lactating cows and adult males of Senegalese native cattle, respectively.
Sensitivity indices based on standardized regression coefficients of input parameters used to calculate enteric methane emission factors for lactating cows of Senegalese native cattle breeds.
Sensitivity indices based on standardized regression coefficients of input parameters used to calculate enteric methane emission factors for adult males of Senegalese native cattle breeds.
According to the linear regression method implemented, the methane conversion rate (Ym) and the coefficient for calculating net energy for maintenance (Cfi) are the parameters with the largest SRC. The results show also the importance of the digestibility of feed (DE%) and liveweight (LW). The rank order in terms of sensitivity was identical for both cattle breeds and each animal sub-category. Moreover, our results reveal that among breeds, the SRC obtained for Ndama cattle was slightly larger. Differences were also observed between sub-categories. Compared to lactating cows, the SRC was higher for adult male Gobra cattle for parameters such as Ym, Cfi, and LW. For lactating cows, compared with adult males, Ym and DE showed more sensitivity for Ndama cattle. However, irrespective of breed or sub-category, the differences observed between SRC of input parameters did not exceed 8%.
To date, because of the scarcity of relevant data in developing countries in the SSA region, the Tier 1 approach is most commonly used to evaluate enteric methane emission from livestock [50, 51]. Assessments at the regional level suggest that Africa has a higher uncertainty for each livestock product compared with Europe [52]. Additionally, [8] reported that only about one third of countries located in developing regions have conducted evaluation of uncertainty in their national GHG inventory. Considering the absence of reliable information on livestock in the SSA region, the IPCC Guidelines suggest that the uncertainty of enteric fermentation emission factors ranges from ±30% to ±50% for Tier 1 and ± 20% for Tier 2 approaches, respectively [5]. Hence, the use of a Tier 2 approach may enable a decrease in the uncertainty of predicted enteric methane emission factors used in national GHG inventories [53, 54, 55]. In Senegal, the third GHG emission inventory was submitted to the UNFCCC in 2015 (see https://unfccc.int/documents/89618). In that inventory, enteric methane emission of cattle was assessed using the Tier 2 methodology. Within the overall emissions from the agricultural sector, enteric methane was identified as a key source of emissions (accounting for 72% of total agricultural emissions). Cattle were responsible for 65% of total agricultural emissions. However, uncertainty analysis has not previously been performed on that national GHG inventory.
Considering the results of both uncertainty and sensitivity analysis computed in this study, our calculations indicate that the coefficient of maintenance (Cfi), the digestibility of feed (DE) and the methane conversion factor (Ym) are the input parameters which require further research, because of their influence on the accuracy of enteric methane emission factors calculated using the 2006 IPCC Tier 2 approach.
The importance of Cfi has been pointed out in previous research conducted in other regions [41, 42, 53]. The value of Cfi implemented in our assessment was sourced from the IPCC Guidelines. To our knowledge, studies focusing on this parameter are very few, particularly in developing countries, despite the dependence of this parameter on variation in temperature [5].
The composition of fodder consumed by ruminants is well documented in Senegal, and the profile of organic matter digestibility (OMd) is available [13, 14, 15, 54]. However, there is a need to determine at the national scale, an average value for OMd which takes into consideration seasonality. To date, the default value for feed digestibility (DE, %) from the IPCC Guidelines (i.e., 50 ± 5%) has always been applied in the Senegalese national GHG inventory. In general, estimation of DE is very complex, considering the various factors which need to be taken into consideration [56, 57, 58]. To estimate DE, robust formula needs to be developed based on numerous data which consider the diversity of diet [59]. For example, in West African livestock farming systems, the largest proportion of feed is from natural pastures [60, 61, 62]. Cattle herds in this region graze different types of feedstuffs (e.g., trees, crop residues, woody species, grasses). Throughout the seasons, the composition of the diet and the nutrient content of feedstuff both fluctuate [13, 63, 64]. Given the diversity of feedstuff and seasonal fluctuations in the West African context, determining an annual average value of DE is challenging. A fixed value for DE is reasonable as it is supposed to represent the annual average. Additionally, apart from the proposed values of DE in the 2006 IPCC Guidelines, reports of the value of DE are very limited in the literature, even in some developed countries. Indeed, with the lack of country-specific data related to the feeding system, Belgium applies DE values from the Netherlands, assuming that feed systems are comparable [65]. Slovenia uses a predicted equation sourced from INRA and German feeding tables [66]. In the national inventory of the UK, the DE values applied for dairy cattle were from tables of nutritive value and chemical composition of feeds, while for beef cattle values were based on expert opinion [67].
The methane conversion factor (Ym, %) is the third parameter which needs to be better estimated when using the Tier 2 approach. Ym is defined as the percent of gross energy intake that is converted into methane (kg CH4/kg GEI). The appropriate value of Ym is the subject of considerable research by scientists [68]. Using a meta-analysis approach, [69] propose using 8.4 ± 0.4% (range 4.8% to 13.7%) for Ym, while [70] suggest a value which varies from 5.0% to 7.2%. Several countries apply values for Ym other than the default values suggested by the 2006 IPCC Guidelines. For example, Croatia calculated Ym using a model reported by [56]. Denmark used a value for Ym for dairy cattle (ranging from 5.98% to 6.13%) reported by [71].
Hence, in view of the diverse diet composition consumed by cattle over the course of the seasons in West Africa [72, 73, 74], determination of an appropriate value for Ym is clearly important for estimating the expected enteric methane emission factor using the IPCC 2006 Tier 2 approach.
In our case, we used expert judgment to characterize the uncertainties of input parameters. In addition, it is possible that the inputs parameters can be correlated. In Senegal, due to the scarcity of relevant reports related to the percentage of native cattle breeds in the total cattle herd, it is probable that uncertainty of activity data is actually higher than uncertainty of emission factors and should be a priority for GHG inventory improvement.
The purpose of conducting uncertainty and sensitivity analysis was to identify the most important factors driving emission factors in order to prioritize future data improvement and research efforts so as to improve livestock GHG emission estimates and reduce the uncertainty of inventory estimates for Senegal. Having applied analysis of variance and regression techniques for uncertainty analysis and sensitivity analysis, respectively, our results suggest that future research should focus on the estimates of the coefficient of maintenance, feed digestibility and the methane conversion factor.
We thank colleagues who contributed to improving this manuscript.
The author declares that no conflicts of interest have affected the conduct of the work proposed in this paper.
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\\n\\n10. IntechOpen Advertising Sales department makes the decisions about the types of advertisements to include or exclude. Placement of advertising is at the discretion of IntechOpen. IntechOpen retains the right to reject and/or request modifications to the advertisement. An advertisement that is visible online, will be withdrawn from the site at any time if the Editor(s) or Author(s) request its removal.
\\n\\n11. Users can make decisions about accepting advertisements. Users can block all the advertisements by using ad blockers. Users can send all the complaints about advertising to: info@intechopen.com.
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\\n"}]'},components:[{type:"htmlEditorComponent",content:'1. IntechOpen partners with third-party companies to serve ads and/or collect certain information when you visit our website. These companies may collect non-personally identifiable information (not including your name, address, email address or telephone number) during your visit to IntechOpen's website.
\n\n2. All advertisements and commercially sponsored publications are independent from editorial decisions.
\n\n3. IntechOpen does not endorse any product or service marked as an advertisement on IntechOpen website.
\n\n4. IntechOpen has blocked all the inappropriate types of advertising.
\n\n5. IntechOpen has blocked advertisement of harmful products or services.
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\n\n9. Types of advertisments:
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\n\n10. IntechOpen Advertising Sales department makes the decisions about the types of advertisements to include or exclude. Placement of advertising is at the discretion of IntechOpen. IntechOpen retains the right to reject and/or request modifications to the advertisement. An advertisement that is visible online, will be withdrawn from the site at any time if the Editor(s) or Author(s) request its removal.
\n\n11. Users can make decisions about accepting advertisements. Users can block all the advertisements by using ad blockers. Users can send all the complaints about advertising to: info@intechopen.com.
\n\nPolicy last updated: 2021-04-28
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Neutrophil effector mechanisms include the release of proinflammatory cytokines, reactive oxygen and nitrogen species (ROS and RNS), and granules containing degradative enzymes, which can cause further damage to the tissue and amplify the neutrophil response. Therefore, the modulation of neutrophil migration and functions is a potential target for pharmacological intervention in arthritis. The pharmacologic treatment options for RA are diverse. The current treatments are mostly symptomatic and have side effects, high costs, and an increased risk of malignancies. Because of these limitations, there is a growing interest in the use of natural products as therapies or adjunct therapies. Herbal products have attracted considerable interest over the past decade because of their multiple beneficial effects such as their antioxidant, anti-inflammatory, antiproliferative, and immunomodulatory properties. This chapter focuses on the role of neutrophils in the pathogenesis of arthritis and the action of substances from natural products as putative antirheumatic therapies.",book:{id:"5834",slug:"role-of-neutrophils-in-disease-pathogenesis",title:"Role of Neutrophils in Disease Pathogenesis",fullTitle:"Role of Neutrophils in Disease Pathogenesis"},signatures:"Elaine Cruz Rosas, Luana Barbosa Correa and Maria das Graças\nHenriques",authors:[{id:"64332",title:"Dr.",name:"Maria Das Graças",middleName:null,surname:"Henriques",slug:"maria-das-gracas-henriques",fullName:"Maria Das Graças Henriques"},{id:"197932",title:"Dr.",name:"Elaine",middleName:"Cruz",surname:"Rosas",slug:"elaine-rosas",fullName:"Elaine Rosas"},{id:"199677",title:"MSc.",name:"Luana",middleName:null,surname:"Correa",slug:"luana-correa",fullName:"Luana Correa"}]},{id:"46041",doi:"10.5772/57335",title:"An Insight into the Abnormal Fibrin Clots — Its Pathophysiological Roles",slug:"an-insight-into-the-abnormal-fibrin-clots-its-pathophysiological-roles",totalDownloads:3892,totalCrossrefCites:4,totalDimensionsCites:11,abstract:null,book:{id:"3836",slug:"fibrinolysis-and-thrombolysis",title:"Fibrinolysis and Thrombolysis",fullTitle:"Fibrinolysis and Thrombolysis"},signatures:"Payel Bhattacharjee and Debasish Bhattacharyya",authors:[{id:"88185",title:"Prof.",name:"Debasish",middleName:null,surname:"Bhattacharyya",slug:"debasish-bhattacharyya",fullName:"Debasish Bhattacharyya"},{id:"170045",title:"Ms.",name:"Payel",middleName:null,surname:"Bhattacharjee",slug:"payel-bhattacharjee",fullName:"Payel Bhattacharjee"}]},{id:"39110",doi:"10.5772/48250",title:"Laboratory Reference Intervals in Africa",slug:"laboratory-reference-intervals-in-africa",totalDownloads:4489,totalCrossrefCites:0,totalDimensionsCites:10,abstract:null,book:{id:"2607",slug:"blood-cell-an-overview-of-studies-in-hematology",title:"Blood Cell",fullTitle:"Blood Cell - An Overview of Studies in Hematology"},signatures:"Clement E. Zeh, Collins O. Odhiambo and Lisa A. Mills",authors:[{id:"141066",title:"Dr",name:"Clement",middleName:null,surname:"Zeh",slug:"clement-zeh",fullName:"Clement Zeh"}]}],mostDownloadedChaptersLast30Days:[{id:"66797",title:"Blood Transfusion Reactions",slug:"blood-transfusion-reactions",totalDownloads:2617,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"Blood transfusion reaction/adverse transfusion reactions could be fatal/severe or mild, immediate or delayed, immunological or nonimmunological, and infectious or noninfectious, and attention is paid particularly to the incidence, possible causes and pathophysiology, clinical features, and management of each type with the aim of improving awareness and raising consciousness towards improving blood safety and judicious use of blood so as to forestall these blood transfusion reactions as much as possible. This chapter serves as a synopsis to adverse blood reactions, which are very common but apparently more often under-recognized and/or under-reported particularly in developing countries. This should sharpen the consciousness of all health practitioners involved in blood transfusion services towards taking measures at preventing transfusion reactions right from donor selection up to the infusion of blood into the recipients.",book:{id:"6905",slug:"blood-groups",title:"Blood Groups",fullTitle:"Blood Groups"},signatures:"John Ayodele Olaniyi",authors:[{id:"202764",title:"Dr.",name:"John",middleName:null,surname:"Olaniyi",slug:"john-olaniyi",fullName:"John Olaniyi"}]},{id:"49387",title:"Thalassemia — From Genotype to Phenotype",slug:"thalassemia-from-genotype-to-phenotype",totalDownloads:4877,totalCrossrefCites:2,totalDimensionsCites:3,abstract:"Thalassemia encompasses serious diseases with complex pathophysiology that is difficult to explain since it is considered a group of defects with similar clinical effects, still not a single disorder.",book:{id:"4729",slug:"inherited-hemoglobin-disorders",title:"Inherited Hemoglobin Disorders",fullTitle:"Inherited Hemoglobin Disorders"},signatures:"Ghada Y. El-Kamah and Khalda S. Amr",authors:[{id:"58735",title:"Prof.",name:"Ghada",middleName:null,surname:"El-Kamah",slug:"ghada-el-kamah",fullName:"Ghada El-Kamah"},{id:"176872",title:"Prof.",name:"Khalda",middleName:null,surname:"Amr",slug:"khalda-amr",fullName:"Khalda Amr"}]},{id:"51831",title:"Disorders Mimicking Myelodysplastic Syndrome and Difficulties in its Diagnosis",slug:"disorders-mimicking-myelodysplastic-syndrome-and-difficulties-in-its-diagnosis",totalDownloads:4511,totalCrossrefCites:1,totalDimensionsCites:6,abstract:"Myelodysplastic morphology of blood cells can be encountered not only in myelodysplastic syndrome (MDS) but also in nonclonal disorders like viral, bacterial, parasitic infections, juvenile rheumatoid arthritis, polyarteritis nodosa, immune thrombocytopenic purpura (ITP), iron deficiency anemia, megaloblastic anemia, dysgranulopoietic neutropenia, congenital neutropenia, cases with microdeletion 22q11.2, malignant lymphoma, after administration of granulocyte colony stimulating factor, chemotherapy, steroids, smoking, alcohol, posttransplantation, copper deficiency also, together with or without cytopenia. Absence of cytogenetic abnormality in 50–70% of cases with MDS, some overlapping morphological and/or pathophysiological features make it challenging to differentiate between MDS and other diseases/disorders like aplastic anemia, refractory ITP, copper deficiency. Transient genetic abnormalities including monosomy 7 in megaloblastic anemia; increased immature myeloid cells in bone marrow of cases with copper, vitamin B12, or folic acid deficiency in the setting of cytopenia and dysmorphism may also lead to the misdiagnosis of MDS. On the other hand, there are also cases of transient MDS. In this chapter, a literature is be presented to draw attention of the readers on the disorders that mimic MDS. Additionally, our personal experiences are also be shared. Awareness of disorders mimicking MDS may prevent over- or underdiagnosis of MDS.",book:{id:"5276",slug:"myelodysplastic-syndromes",title:"Myelodysplastic Syndromes",fullTitle:"Myelodysplastic Syndromes"},signatures:"Lale Olcay and Sevgi Yetgin",authors:[{id:"184156",title:"Prof.",name:"Lale",middleName:null,surname:"Olcay",slug:"lale-olcay",fullName:"Lale Olcay"}]},{id:"64871",title:"Diagnosis and Classification of Myelodysplastic Syndrome",slug:"diagnosis-and-classification-of-myelodysplastic-syndrome",totalDownloads:3212,totalCrossrefCites:0,totalDimensionsCites:1,abstract:"Myelodysplastic syndrome (MDS) is a clonal hematopoietic stem cell disorder characterized by morphological dysplastic changes in one or more of the major hematopoietic cell lines. MDS can present with varying degrees of single or multiple cytopenias including neutropenia, anemia and thrombocytopenia. Presentation of MDS can range from asymptomatic to life threatening. MDS diagnosis and classification present important challenges, particularly in the distinction from benign conditions. French-American-British (FAB) classification proposed a classification based on easily obtainable laboratory information and was recommended in early and as modified by guidelines of new classification of World Health Organization (WHO). The strategy of diagnostic laboratory in MDS depends on morphological changes and is based on existence of dysplastic changes in the peripheral blood and bone marrow including peripheral blood smear, bone marrow aspirate smear and bone marrow trephine biopsy. The correct morphological interpretation and the use of cytogenetics, immunophenotyping, immunohistochemistry and molecular analysis will give valuable information on diagnosis and prognosis.",book:{id:"7138",slug:"recent-developments-in-myelodysplastic-syndromes",title:"Recent Developments in Myelodysplastic Syndromes",fullTitle:"Recent Developments in Myelodysplastic Syndromes"},signatures:"Gamal Abdul Hamid, Abdul Wahab Al-Nehmi and Safa Shukry",authors:[{id:"36487",title:"Prof.",name:"Gamal",middleName:null,surname:"Abdul Hamid",slug:"gamal-abdul-hamid",fullName:"Gamal Abdul Hamid"},{id:"273724",title:"Dr.",name:"Safa",middleName:null,surname:"Shukry",slug:"safa-shukry",fullName:"Safa Shukry"},{id:"277511",title:"Dr.",name:"Abdulwahab",middleName:null,surname:"Al-Nehmi",slug:"abdulwahab-al-nehmi",fullName:"Abdulwahab Al-Nehmi"}]},{id:"70780",title:"Laboratory Diagnosis of β-Thalassemia and HbE",slug:"laboratory-diagnosis-of-thalassemia-and-hbe",totalDownloads:1400,totalCrossrefCites:1,totalDimensionsCites:2,abstract:"β-Thalassemia and HbE, each, is a syndrome resulted from quantitative and qualitative defects of β-globin chain, respectively. In addition to history retrieve and physical examination, diagnosis of these disorders requires laboratory information. Laboratory tests that are conventionally performed to diagnose the β-thalassemia and HbE are classified into two groups, based on the purposes, including the screening tests and confirmatory tests. The screening tests are aimed to screen for carriers of the β-thalassemia and HbE, while confirmatory tests are the tests performed to definitely diagnose these disorders. This chapter will explain all of these tests, the information of which will be useful for those who are working and interested in the β-thalassemia and HbE.",book:{id:"8450",slug:"beta-thalassemia",title:"Beta Thalassemia",fullTitle:"Beta Thalassemia"},signatures:"Thanusak Tatu",authors:null}],onlineFirstChaptersFilter:{topicId:"183",limit:6,offset:0},onlineFirstChaptersCollection:[{id:"82161",title:"Blood Groups More than Inheritance of Antigenic Substances: Susceptibility to Some Diseases",slug:"blood-groups-more-than-inheritance-of-antigenic-substances-susceptibility-to-some-diseases",totalDownloads:9,totalDimensionsCites:0,doi:"10.5772/intechopen.104593",abstract:"Blood group antigens represent polymorphic traits inherited among individuals and populations. The objective of this chapter is to review articles that have reported; the association between blood group antigens and susceptibility to some diseases. Findings showed that O blood group had a greater frequency of severe infections such as E coli, cholera and blood group A was associated with incidence of smallpox and some bacterial infections. These are principally based on presence or absence of “H-like” and “A and B-like” antigens markers. Antigens A, B and H are connected to N-glycans of vWF and reduces the half-life of the protein (10 hours) for group O while non-O groups, 25 hours. The loss of A, B, and H antigens as malignancy progresses was linked to potential metastasis. Similarly, some tumors have A or A-like antigens this explains the propensity of group A to develop tumors. Blood type incompatibility between mother and foetus sensitizes the mother to develop alloantibodies that could potentially cause death of the foetus in utero, a condition known hydrops. Reviewed articles have reported close link between blood group antigens and susceptibility diseases. More studies are required to rationalize the mechanism associated to this.",book:{id:"10728",title:"Blood Groups - More Than Inheritance of Antigenic Substances",coverURL:"https://cdn.intechopen.com/books/images_new/10728.jpg"},signatures:"Williams Bitty Azachi and Kuschak Mathias Dakop"},{id:"80344",title:"RH Groups",slug:"rh-groups",totalDownloads:25,totalDimensionsCites:0,doi:"10.5772/intechopen.102421",abstract:"In 1939, a mother gave birth to a stillborn baby and underwent blood transfusion with ABO-matched blood from her husband. This resulted in a hemolytic transfusion reaction (HTR). Levine and Stetson postulated that a novel antigen was present in the baby and father, which was absent in the mother. Therefore, the mother’s immune system recognized this antigen and produced antibodies against it. This condition has been known as the hemolytic disease of the newborn for a long period of time. Since the antenatal management of the fetus has been developed, the term has been modified to hemolytic disease of the fetus and newborn (HDFN). This case led to the discovery of the antibody against the first antigen of the RH blood group system, the D antigen. To date, 56 antigens have been recognized within the RH blood group system. The five main antigens are D, C, c, E, and e. As observed in the above-mentioned case, the antibodies against these antigens are implicated in HTR and HDFN.",book:{id:"10728",title:"Blood Groups - More Than Inheritance of Antigenic Substances",coverURL:"https://cdn.intechopen.com/books/images_new/10728.jpg"},signatures:"Amr J. Halawani"},{id:"80254",title:"Neutrophil-Specific Antigens: Immunobiology, Genetics and Roles in Clinical Disorders",slug:"neutrophil-specific-antigens-immunobiology-genetics-and-roles-in-clinical-disorders",totalDownloads:36,totalDimensionsCites:0,doi:"10.5772/intechopen.102431",abstract:"Neutrophils are the most abundant nucleated cells in blood circulation and play important roles in the innate and adaptive immune responses. Neutrophil-specific antigens, only expressed on neutrophils, are glycoproteins originally identified in studies on neonatal neutropenia due to fetal-maternal incompatibility and autoimmune neutropenia of infancy. The most investigated neutrophil–specific antigens are the NA and NB antigens that their incompatibilities also cause transfusion-induced febrile reactions and acute lung injury, a potentially fatal reaction, and in bone marrow transplantation, causing graft rejection. NA antigens are members of the immunoglobulin superfamily and are low-affinity Fc-receptors FcγRIIIb (CD16b). Fc receptors connect the F(ab), the antigen-binding fragment of the antibody molecules, to neutrophils and lead them to recognize and phagocytize the targeted antigens. The NB (CD177) antigen belongs to the urokinase-type Plasminogen Activator Receptor Superfamily (uPAR, CD59, Ly6), but its specific functions have not been fully determined. It is known, however, that NB antigen binds proteinase-3 (PR3 to the neutrophil membrane), a serine protease. In clinical studies, it was also demonstrated that NB expression is highly elevated in Polycythemia Vera and is unexpectedly expressed in some cancer tissues. Neutrophil-specific antigens are examples of antigens that have important biological and clinical activities beyond antigenicity.",book:{id:"10728",title:"Blood Groups - More Than Inheritance of Antigenic Substances",coverURL:"https://cdn.intechopen.com/books/images_new/10728.jpg"},signatures:"Parviz Lalezari and Behnaz Bayat"},{id:"80716",title:"The ABO Blood Group System and Plasmodium falciparum (Pf ) Infection in Three Ethnic Groups Living in the Stable and Seasonal Malaria Transmission Areas of Burkina Faso (BF)",slug:"the-abo-blood-group-system-and-plasmodium-falciparum-pf-infection-in-three-ethnic-groups-living-in-t",totalDownloads:92,totalDimensionsCites:0,doi:"10.5772/intechopen.102475",abstract:"Genetic factors, including red blood cell polymorphisms, influence the severity of disease due to infection with Plasmodium falciparum (Pf). Studies show that these genetic factors associated with malaria susceptibility or resistance vary geographically, ethnically, and racially. We performed cross-sectional surveys in population living in rural villages from three ethnic groups. The blood group (BG) was determined genetically using two polymorphisms (rs8176719 and rs8176746). Out of 548 participants, 29.7% were Mossi, 38.2% were Fulani, and 32.1% were Rimaibe. The distribution of BG was, respectively, A: 25.5%, B: 26.6%, AB: 7.3%, and O: 40.5%. BG O was not only the common blood type overall, but was higher in Fulani (52.6%) than others. Fulani was associated with a reduced risk of infection and lower parasite densities than sympatric populations. The subjects with non-O blood were less susceptible to malaria infection. An association between ethnicity and malaria infection during the high transmission season as well as an association between the non-O blood group and malaria infections according to ethnicity was found. This was also true when ethnic groups were considered separately. Our results have demonstrated that the Fulani are not only less susceptible to Pf malaria infection, but when infected have lower parasite densities. Individuals with non-O blood are at lower risk of infection.",book:{id:"10728",title:"Blood Groups - More Than Inheritance of Antigenic Substances",coverURL:"https://cdn.intechopen.com/books/images_new/10728.jpg"},signatures:"Edith Christiane Bougouma, Alphonse Ouedraogo and Sodiomon Bienvenu Sirima"},{id:"80474",title:"ABO Blood Group and Thromboembolic Diseases",slug:"abo-blood-group-and-thromboembolic-diseases",totalDownloads:42,totalDimensionsCites:0,doi:"10.5772/intechopen.102757",abstract:"Thromboembolic diseases are usually inherited in the family. The tendency to repeat in an individual is a phenomenon that allows it to be studied. The inheritance and recurrence of thromboembolic diseases, of course, have individual risk factors for this occurrence. In the past, the ABO blood group was only needed for transfusion and organ transplant therapy. Over time, scientists think that blood type is a risk factor for certain diseases, including thromboembolism. Many studies divide between type O and non-O blood groups, both of which are distinguished by the presence of antigens on the cell surface and antibodies in the plasma of individuals. Type O does not have A, B antigens but has antibodies against A, B antigens, and vice versa for the non-O type. Many studies have shown that the non-O blood group has a risk factor for thromboembolic diseases, commonly due to higher levels of von Willebrand factor (VWF) and factor VIII (FVIII). These thromboembolic events can occur in arteries or venous. Thromboembolic manifestations are often associated with cardiovascular diseases for arterial thrombosis; and deep vein thrombosis (DVT) and pulmonary embolism (PE) for venous thromboembolism (VTE).",book:{id:"10728",title:"Blood Groups - More Than Inheritance of Antigenic Substances",coverURL:"https://cdn.intechopen.com/books/images_new/10728.jpg"},signatures:"Yetti Hernaningsih"},{id:"78997",title:"ABO Blood Groups and Risk of Glioma",slug:"abo-blood-groups-and-risk-of-glioma",totalDownloads:59,totalDimensionsCites:0,doi:"10.5772/intechopen.100566",abstract:"Gliomas are one of the most common primary brain tumors and the etiology of gliomas remains unknown in most cases. The aim of this case–control study was to investigate possible association between incidence in relation to glioma and certain blood groups. This study included 100 histopathologically verified cases of glioma and 200 age and sex-matched controls without malignant diseases that were admitted to the same hospital. The results revealed that the patients with group AB were at 3.5-fold increased risk of developing glioma compared to the patients with other ABO blood groups. In this particular study, there was more male patients with glioma with the blood group AB. However, mechanisms that explain the relationship between the blood groups ABO and a cancer risk are unclear. Several hypotheses have been proposed, including the one with a modulatory role of blood group ABO antigens. In addition, the blood group ABO system regulates the level of circulating proinflammatory and adhesion molecules which play a significant role in the tumorigenesis process. Additionally, the recent discovery that includes the von Willebrand factor (vWF) as an important modulator of angiogenesis and apoptosis provides one plausible explanation as regards the role of the blood group ABO in the tumorigenesis process. To our knowledge, this is the first study that examined the relationship of blood group in patients diagnosed with glioma among the Serbian population. Moreover, for the first time our study results suggested that blood group AB increased the risk of glioma. The results of this study suggested that the blood group AB could be one of hereditary factors which had an influence on the occurrence of glioma. The further research is needed on a larger sample, to confirm these findings and the possible mechanisms by which the ABO system contributes to the pathology of glioma.",book:{id:"10728",title:"Blood Groups - More Than Inheritance of Antigenic Substances",coverURL:"https://cdn.intechopen.com/books/images_new/10728.jpg"},signatures:"Ana Azanjac Arsic"}],onlineFirstChaptersTotal:7},preDownload:{success:null,errors:{}},subscriptionForm:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[],offset:8,limit:8,total:0},allSeries:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:9,numberOfPublishedChapters:89,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:104,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:32,numberOfPublishedChapters:318,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:12,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:11,numberOfPublishedChapters:141,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:8,numberOfPublishedChapters:129,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!0},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:113,numberOfOpenTopics:3,numberOfUpcomingTopics:1,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:11,numberOfPublishedChapters:106,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2753-894X",doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:5,numberOfOpenTopics:1,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!0},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:0,numberOfPublishedChapters:15,numberOfOpenTopics:5,numberOfUpcomingTopics:0,issn:null,doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],testimonialsList:[{id:"13",text:"The collaboration with and support of the technical staff of IntechOpen is fantastic. The whole process of submitting an article and editing of the submitted article goes extremely smooth and fast, the number of reads and downloads of chapters is high, and the contributions are also frequently cited.",author:{id:"55578",name:"Antonio",surname:"Jurado-Navas",institutionString:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRisIQAS/Profile_Picture_1626166543950",slug:"antonio-jurado-navas",institution:{id:"720",name:"University of Malaga",country:{id:null,name:"Spain"}}}},{id:"6",text:"It is great to work with the IntechOpen to produce a worthwhile collection of research that also becomes a great educational resource and guide for future research endeavors.",author:{id:"259298",name:"Edward",surname:"Narayan",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259298/images/system/259298.jpeg",slug:"edward-narayan",institution:{id:"3",name:"University of Queensland",country:{id:null,name:"Australia"}}}}]},series:{item:{id:"14",title:"Artificial Intelligence",doi:"10.5772/intechopen.79920",issn:"2633-1403",scope:"Artificial Intelligence (AI) is a rapidly developing multidisciplinary research area that aims to solve increasingly complex problems. In today's highly integrated world, AI promises to become a robust and powerful means for obtaining solutions to previously unsolvable problems. This Series is intended for researchers and students alike interested in this fascinating field and its many applications.",coverUrl:"https://cdn.intechopen.com/series/covers/14.jpg",latestPublicationDate:"June 11th, 2022",hasOnlineFirst:!0,numberOfPublishedBooks:9,editor:{id:"218714",title:"Prof.",name:"Andries",middleName:null,surname:"Engelbrecht",slug:"andries-engelbrecht",fullName:"Andries Engelbrecht",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRNR8QAO/Profile_Picture_1622640468300",biography:"Andries Engelbrecht received the Masters and PhD degrees in Computer Science from the University of Stellenbosch, South Africa, in 1994 and 1999 respectively. He is currently appointed as the Voigt Chair in Data Science in the Department of Industrial Engineering, with a joint appointment as Professor in the Computer Science Division, Stellenbosch University. Prior to his appointment at Stellenbosch University, he has been at the University of Pretoria, Department of Computer Science (1998-2018), where he was appointed as South Africa Research Chair in Artifical Intelligence (2007-2018), the head of the Department of Computer Science (2008-2017), and Director of the Institute for Big Data and Data Science (2017-2018). In addition to a number of research articles, he has written two books, Computational Intelligence: An Introduction and Fundamentals of Computational Swarm Intelligence.",institutionString:null,institution:{name:"Stellenbosch University",institutionURL:null,country:{name:"South Africa"}}},editorTwo:null,editorThree:null},subseries:{paginationCount:6,paginationItems:[{id:"22",title:"Applied Intelligence",coverUrl:"https://cdn.intechopen.com/series_topics/covers/22.jpg",isOpenForSubmission:!0,editor:{id:"27170",title:"Prof.",name:"Carlos",middleName:"M.",surname:"Travieso-Gonzalez",slug:"carlos-travieso-gonzalez",fullName:"Carlos Travieso-Gonzalez",profilePictureURL:"https://mts.intechopen.com/storage/users/27170/images/system/27170.jpeg",biography:"Carlos M. Travieso-González received his MSc degree in Telecommunication Engineering at Polytechnic University of Catalonia (UPC), Spain in 1997, and his Ph.D. degree in 2002 at the University of Las Palmas de Gran Canaria (ULPGC-Spain). He is a full professor of signal processing and pattern recognition and is head of the Signals and Communications Department at ULPGC, teaching from 2001 on subjects on signal processing and learning theory. His research lines are biometrics, biomedical signals and images, data mining, classification system, signal and image processing, machine learning, and environmental intelligence. He has researched in 52 international and Spanish research projects, some of them as head researcher. He is co-author of 4 books, co-editor of 27 proceedings books, guest editor for 8 JCR-ISI international journals, and up to 24 book chapters. He has over 450 papers published in international journals and conferences (81 of them indexed on JCR – ISI - Web of Science). He has published seven patents in the Spanish Patent and Trademark Office. He has been a supervisor on 8 Ph.D. theses (11 more are under supervision), and 130 master theses. He is the founder of The IEEE IWOBI conference series and the president of its Steering Committee, as well as the founder of both the InnoEducaTIC and APPIS conference series. He is an evaluator of project proposals for the European Union (H2020), Medical Research Council (MRC, UK), Spanish Government (ANECA, Spain), Research National Agency (ANR, France), DAAD (Germany), Argentinian Government, and the Colombian Institutions. He has been a reviewer in different indexed international journals (<70) and conferences (<250) since 2001. He has been a member of the IASTED Technical Committee on Image Processing from 2007 and a member of the IASTED Technical Committee on Artificial Intelligence and Expert Systems from 2011. \n\nHe has held the general chair position for the following: ACM-APPIS (2020, 2021), IEEE-IWOBI (2019, 2020 and 2020), A PPIS (2018, 2019), IEEE-IWOBI (2014, 2015, 2017, 2018), InnoEducaTIC (2014, 2017), IEEE-INES (2013), NoLISP (2011), JRBP (2012), and IEEE-ICCST (2005)\n\nHe is an associate editor of the Computational Intelligence and Neuroscience Journal (Hindawi – Q2 JCR-ISI). He was vice dean from 2004 to 2010 in the Higher Technical School of Telecommunication Engineers at ULPGC and the vice dean of Graduate and Postgraduate Studies from March 2013 to November 2017. He won the “Catedra Telefonica” Awards in Modality of Knowledge Transfer, 2017, 2018, and 2019 editions, and awards in Modality of COVID Research in 2020.\n\nPublic References:\nResearcher ID http://www.researcherid.com/rid/N-5967-2014\nORCID https://orcid.org/0000-0002-4621-2768 \nScopus Author ID https://www.scopus.com/authid/detail.uri?authorId=6602376272\nScholar Google https://scholar.google.es/citations?user=G1ks9nIAAAAJ&hl=en \nResearchGate https://www.researchgate.net/profile/Carlos_Travieso",institutionString:null,institution:{name:"University of Las Palmas de Gran Canaria",institutionURL:null,country:{name:"Spain"}}},editorTwo:null,editorThree:null},{id:"23",title:"Computational Neuroscience",coverUrl:"https://cdn.intechopen.com/series_topics/covers/23.jpg",isOpenForSubmission:!0,editor:{id:"14004",title:"Dr.",name:"Magnus",middleName:null,surname:"Johnsson",slug:"magnus-johnsson",fullName:"Magnus Johnsson",profilePictureURL:"https://mts.intechopen.com/storage/users/14004/images/system/14004.png",biography:"Dr Magnus Johnsson is a cross-disciplinary scientist, lecturer, scientific editor and AI/machine learning consultant from Sweden. \n\nHe is currently at Malmö University in Sweden, but also held positions at Lund University in Sweden and at Moscow Engineering Physics Institute. \nHe holds editorial positions at several international scientific journals and has served as a scientific editor for books and special journal issues. \nHis research interests are wide and include, but are not limited to, autonomous systems, computer modeling, artificial neural networks, artificial intelligence, cognitive neuroscience, cognitive robotics, cognitive architectures, cognitive aids and the philosophy of mind. \n\nDr. Johnsson has experience from working in the industry and he has a keen interest in the application of neural networks and artificial intelligence to fields like industry, finance, and medicine. \n\nWeb page: www.magnusjohnsson.se",institutionString:null,institution:{name:"Malmö University",institutionURL:null,country:{name:"Sweden"}}},editorTwo:null,editorThree:null},{id:"24",title:"Computer Vision",coverUrl:"https://cdn.intechopen.com/series_topics/covers/24.jpg",isOpenForSubmission:!0,editor:{id:"294154",title:"Prof.",name:"George",middleName:null,surname:"Papakostas",slug:"george-papakostas",fullName:"George Papakostas",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002hYaGbQAK/Profile_Picture_1624519712088",biography:"George A. 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He has (co)authored more than 150 publications in indexed journals, international conferences and book chapters, 1 book (in Greek), 3 edited books, and 5 journal special issues. His publications have more than 2100 citations with h-index 27 (GoogleScholar). His research interests include computer/machine vision, machine learning, pattern recognition, computational intelligence. \nDr. Papakostas served as a reviewer in numerous journals, as a program\ncommittee member in international conferences and he is a member of the IAENG, MIR Labs, EUCogIII, INSTICC and the Technical Chamber of Greece (TEE).",institutionString:null,institution:{name:"International Hellenic University",institutionURL:null,country:{name:"Greece"}}},editorTwo:null,editorThree:null},{id:"25",title:"Evolutionary Computation",coverUrl:"https://cdn.intechopen.com/series_topics/covers/25.jpg",isOpenForSubmission:!0,editor:{id:"136112",title:"Dr.",name:"Sebastian",middleName:null,surname:"Ventura Soto",slug:"sebastian-ventura-soto",fullName:"Sebastian Ventura Soto",profilePictureURL:"https://mts.intechopen.com/storage/users/136112/images/system/136112.png",biography:"Sebastian Ventura is a Spanish researcher, a full professor with the Department of Computer Science and Numerical Analysis, University of Córdoba. Dr Ventura also holds the positions of Affiliated Professor at Virginia Commonwealth University (Richmond, USA) and Distinguished Adjunct Professor at King Abdulaziz University (Jeddah, Saudi Arabia). Additionally, he is deputy director of the Andalusian Research Institute in Data Science and Computational Intelligence (DaSCI) and heads the Knowledge Discovery and Intelligent Systems Research Laboratory. He has published more than ten books and over 300 articles in journals and scientific conferences. Currently, his work has received over 18,000 citations according to Google Scholar, including more than 2200 citations in 2020. In the last five years, he has published more than 60 papers in international journals indexed in the JCR (around 70% of them belonging to first quartile journals) and he has edited some Springer books “Supervised Descriptive Pattern Mining” (2018), “Multiple Instance Learning - Foundations and Algorithms” (2016), and “Pattern Mining with Evolutionary Algorithms” (2016). He has also been involved in more than 20 research projects supported by the Spanish and Andalusian governments and the European Union. He currently belongs to the editorial board of PeerJ Computer Science, Information Fusion and Engineering Applications of Artificial Intelligence journals, being also associate editor of Applied Computational Intelligence and Soft Computing and IEEE Transactions on Cybernetics. Finally, he is editor-in-chief of Progress in Artificial Intelligence. He is a Senior Member of the IEEE Computer, the IEEE Computational Intelligence, and the IEEE Systems, Man, and Cybernetics Societies, and the Association of Computing Machinery (ACM). Finally, his main research interests include data science, computational intelligence, and their applications.",institutionString:null,institution:{name:"University of Córdoba",institutionURL:null,country:{name:"Spain"}}},editorTwo:null,editorThree:null},{id:"26",title:"Machine Learning and Data Mining",coverUrl:"https://cdn.intechopen.com/series_topics/covers/26.jpg",isOpenForSubmission:!0,editor:{id:"24555",title:"Dr.",name:"Marco Antonio",middleName:null,surname:"Aceves Fernandez",slug:"marco-antonio-aceves-fernandez",fullName:"Marco Antonio Aceves Fernandez",profilePictureURL:"https://mts.intechopen.com/storage/users/24555/images/system/24555.jpg",biography:"Dr. Marco Antonio Aceves Fernandez obtained his B.Sc. (Eng.) in Telematics from the Universidad de Colima, Mexico. 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He is currently a principal researcher in data analytics and optimisation at TECNALIA (Spain), a visiting fellow at the Basque Center for Applied Mathematics (BCAM) and a part-time lecturer at the University of the Basque Country (UPV/EHU). His research interests gravitate on the use of descriptive, prescriptive and predictive algorithms for data mining and optimization in a diverse range of application fields such as Energy, Transport, Telecommunications, Health and Industry, among others. In these fields he has published more than 240 articles, co-supervised 8 Ph.D. theses, edited 6 books, coauthored 7 patents and participated/led more than 40 research projects. 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She is now a lecturer at the University of Witwatersrand, South Africa, and a principal researcher at the Health Economics and Epidemiology Research Office (HE2RO), South Africa. Dr. Moolla holds a Ph.D. in Psychology with her research being focused on mental health and resilience. In her professional work capacity, her research has further expanded into the fields of early childhood development, mental health, the HIV and TB care cascades, as well as COVID. She is also a UNESCO-trained International Bioethics Facilitator.",institutionString:"University of the Witwatersrand",institution:{name:"University of the Witwatersrand",country:{name:"South Africa"}}},{id:"419588",title:"Ph.D.",name:"Sergio",middleName:"Alexandre",surname:"Gehrke",slug:"sergio-gehrke",fullName:"Sergio Gehrke",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000038WgMKQA0/Profile_Picture_2022-06-02T11:44:20.jpg",biography:"Dr. Sergio Alexandre Gehrke is a doctorate holder in two fields. The first is a Ph.D. in Cellular and Molecular Biology from the Pontificia Catholic University, Porto Alegre, Brazil, in 2010 and the other is an International Ph.D. in Bioengineering from the Universidad Miguel Hernandez, Elche/Alicante, Spain, obtained in 2020. In 2018, he completed a postdoctoral fellowship in Materials Engineering in the NUCLEMAT of the Pontificia Catholic University, Porto Alegre, Brazil. He is currently the Director of the Postgraduate Program in Implantology of the Bioface/UCAM/PgO (Montevideo, Uruguay), Director of the Cathedra of Biotechnology of the Catholic University of Murcia (Murcia, Spain), an Extraordinary Full Professor of the Catholic University of Murcia (Murcia, Spain) as well as the Director of the private center of research Biotecnos – Technology and Science (Montevideo, Uruguay). Applied biomaterials, cellular and molecular biology, and dental implants are among his research interests. He has published several original papers in renowned journals. In addition, he is also a Collaborating Professor in several Postgraduate programs at different universities all over the world.",institutionString:null,institution:{name:"Universidad Católica San Antonio de Murcia",country:{name:"Spain"}}},{id:"342152",title:"Dr.",name:"Santo",middleName:null,surname:"Grace Umesh",slug:"santo-grace-umesh",fullName:"Santo Grace Umesh",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/342152/images/16311_n.jpg",biography:null,institutionString:null,institution:{name:"SRM Dental College",country:{name:"India"}}},{id:"333647",title:"Dr.",name:"Shreya",middleName:null,surname:"Kishore",slug:"shreya-kishore",fullName:"Shreya Kishore",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/333647/images/14701_n.jpg",biography:"Dr. Shreya Kishore completed her Bachelor in Dental Surgery in Chettinad Dental College and Research Institute, Chennai, and her Master of Dental Surgery (Orthodontics) in Saveetha Dental College, Chennai. She is also Invisalign certified. She’s working as a Senior Lecturer in the Department of Orthodontics, SRM Dental College since November 2019. She is actively involved in teaching orthodontics to the undergraduates and the postgraduates. Her clinical research topics include new orthodontic brackets, fixed appliances and TADs. She’s published 4 articles in well renowned indexed journals and has a published patency of her own. Her private practice is currently limited to orthodontics and works as a consultant in various clinics.",institutionString:null,institution:{name:"SRM Dental College",country:{name:"India"}}},{id:"323731",title:"Prof.",name:"Deepak M.",middleName:"Macchindra",surname:"Vikhe",slug:"deepak-m.-vikhe",fullName:"Deepak M. Vikhe",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/323731/images/13613_n.jpg",biography:"Dr Deepak M.Vikhe .\n\n\t\n\tDr Deepak M.Vikhe , completed his Masters & PhD in Prosthodontics from Rural Dental College, Loni securing third rank in the Pravara Institute of Medical Sciences Deemed University. He was awarded Dr.G.C.DAS Memorial Award for Research on Implants at 39th IPS conference Dubai (U A E).He has two patents under his name. He has received Dr.Saraswati medal award for best research for implant study in 2017.He has received Fully funded scholarship to Spain ,university of Santiago de Compostela. He has completed fellowship in Implantlogy from Noble Biocare. \nHe has attended various conferences and CDE programmes and has national publications to his credit. His field of interest is in Implant supported prosthesis. Presently he is working as a associate professor in the Dept of Prosthodontics, Rural Dental College, Loni and maintains a successful private practice specialising in Implantology at Rahata.\n\nEmail: drdeepak_mvikhe@yahoo.com..................",institutionString:null,institution:{name:"Pravara Institute of Medical Sciences",country:{name:"India"}}},{id:"204110",title:"Dr.",name:"Ahmed A.",middleName:null,surname:"Madfa",slug:"ahmed-a.-madfa",fullName:"Ahmed A. Madfa",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/204110/images/system/204110.jpg",biography:"Dr. Madfa is currently Associate Professor of Endodontics at Thamar University and a visiting lecturer at Sana'a University and University of Sciences and Technology. He has more than 6 years of experience in teaching. His research interests include root canal morphology, functionally graded concept, dental biomaterials, epidemiology and dental education, biomimetic restoration, finite element analysis and endodontic regeneration. Dr. Madfa has numerous international publications, full articles, two patents, a book and a book chapter. Furthermore, he won 14 international scientific awards. Furthermore, he is involved in many academic activities ranging from editorial board member, reviewer for many international journals and postgraduate students' supervisor. Besides, I deliver many courses and training workshops at various scientific events. Dr. Madfa also regularly attends international conferences and holds administrative positions (Deputy Dean of the Faculty for Students’ & Academic Affairs and Deputy Head of Research Unit).",institutionString:"Thamar University",institution:null},{id:"210472",title:"Dr.",name:"Nermin",middleName:"Mohammed Ahmed",surname:"Yussif",slug:"nermin-yussif",fullName:"Nermin Yussif",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/210472/images/system/210472.jpg",biography:"Dr. Nermin Mohammed Ahmed Yussif is working at the Faculty of dentistry, University for October university for modern sciences and arts (MSA). Her areas of expertise include: periodontology, dental laserology, oral implantology, periodontal plastic surgeries, oral mesotherapy, nutrition, dental pharmacology. She is an editor and reviewer in numerous international journals.",institutionString:"MSA University",institution:null},{id:"204606",title:"Dr.",name:"Serdar",middleName:null,surname:"Gözler",slug:"serdar-gozler",fullName:"Serdar Gözler",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/204606/images/system/204606.jpeg",biography:"Dr. Serdar Gözler has completed his undergraduate studies at the Marmara University Faculty of Dentistry in 1978, followed by an assistantship in the Prosthesis Department of Dicle University Faculty of Dentistry. Starting his PhD work on non-resilient overdentures with Assoc. Prof. Hüsnü Yavuzyılmaz, he continued his studies with Prof. Dr. Gürbüz Öztürk of Istanbul University Faculty of Dentistry Department of Prosthodontics, this time on Gnatology. He attended training programs on occlusion, neurology, neurophysiology, EMG, radiology and biostatistics. In 1982, he presented his PhD thesis \\Gerber and Lauritzen Occlusion Analysis Techniques: Diagnosis Values,\\ at Istanbul University School of Dentistry, Department of Prosthodontics. As he was also working with Prof. Senih Çalıkkocaoğlu on The Physiology of Chewing at the same time, Gözler has written a chapter in Çalıkkocaoğlu\\'s book \\Complete Prostheses\\ entitled \\The Place of Neuromuscular Mechanism in Prosthetic Dentistry.\\ The book was published five times since by the Istanbul University Publications. Having presented in various conferences about occlusion analysis until 1998, Dr. Gözler has also decided to use the T-Scan II occlusion analysis method. Having been personally trained by Dr. Robert Kerstein on this method, Dr. Gözler has been lecturing on the T-Scan Occlusion Analysis Method in conferences both in Turkey and abroad. Dr. Gözler has various articles and presentations on Digital Occlusion Analysis methods. He is now Head of the TMD Clinic at Prosthodontic Department of Faculty of Dentistry , Istanbul Aydın University , Turkey.",institutionString:"Istanbul Aydin University",institution:{name:"Istanbul Aydın University",country:{name:"Turkey"}}},{id:"240870",title:"Ph.D.",name:"Alaa Eddin Omar",middleName:null,surname:"Al Ostwani",slug:"alaa-eddin-omar-al-ostwani",fullName:"Alaa Eddin Omar Al Ostwani",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/240870/images/system/240870.jpeg",biography:"Dr. Al Ostwani Alaa Eddin Omar received his Master in dentistry from Damascus University in 2010, and his Ph.D. in Pediatric Dentistry from Damascus University in 2014. Dr. Al Ostwani is an assistant professor and faculty member at IUST University since 2014. \nDuring his academic experience, he has received several awards including the scientific research award from the Union of Arab Universities, the Syrian gold medal and the international gold medal for invention and creativity. Dr. Al Ostwani is a Member of the International Association of Dental Traumatology and the Syrian Society for Research and Preventive Dentistry since 2017. He is also a Member of the Reviewer Board of International Journal of Dental Medicine (IJDM), and the Indian Journal of Conservative and Endodontics since 2016.",institutionString:"International University for Science and Technology.",institution:{name:"Islamic University of Science and Technology",country:{name:"India"}}},{id:"42847",title:"Dr.",name:"Belma",middleName:null,surname:"Işik Aslan",slug:"belma-isik-aslan",fullName:"Belma Işik Aslan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/42847/images/system/42847.jpg",biography:"Dr. Belma IşIk Aslan was born in 1976 in Ankara-TURKEY. After graduating from TED Ankara College in 1994, she attended to Gazi University, Faculty of Dentistry in Ankara. She completed her PhD in orthodontic education at Gazi University between 1999-2005. Dr. Işık Aslan stayed at the Providence Hospital Craniofacial Institude and Reconstructive Surgery in Michigan, USA for three months as an observer. She worked as a specialist doctor at Gazi University, Dentistry Faculty, Department of Orthodontics between 2005-2014. She was appointed as associate professor in January, 2014 and as professor in 2021. Dr. Işık Aslan still works as an instructor at the same faculty. She has published a total of 35 articles, 10 book chapters, 39 conference proceedings both internationally and nationally. Also she was the academic editor of the international book 'Current Advances in Orthodontics'. She is a member of the Turkish Orthodontic Society and Turkish Cleft Lip and Palate Society. She is married and has 2 children. Her knowledge of English is at an advanced level.",institutionString:"Gazi University Dentistry Faculty Department of Orthodontics",institution:null},{id:"178412",title:"Associate Prof.",name:"Guhan",middleName:null,surname:"Dergin",slug:"guhan-dergin",fullName:"Guhan Dergin",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/178412/images/6954_n.jpg",biography:"Assoc. Prof. Dr. Gühan Dergin was born in 1973 in Izmit. He graduated from Marmara University Faculty of Dentistry in 1999. He completed his specialty of OMFS surgery in Marmara University Faculty of Dentistry and obtained his PhD degree in 2006. In 2005, he was invited as a visiting doctor in the Oral and Maxillofacial Surgery Department of the University of North Carolina, USA, where he went on a scholarship. Dr. Dergin still continues his academic career as an associate professor in Marmara University Faculty of Dentistry. He has many articles in international and national scientific journals and chapters in books.",institutionString:null,institution:{name:"Marmara University",country:{name:"Turkey"}}},{id:"178414",title:"Prof.",name:"Yusuf",middleName:null,surname:"Emes",slug:"yusuf-emes",fullName:"Yusuf Emes",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/178414/images/6953_n.jpg",biography:"Born in Istanbul in 1974, Dr. Emes graduated from Istanbul University Faculty of Dentistry in 1997 and completed his PhD degree in Istanbul University faculty of Dentistry Department of Oral and Maxillofacial Surgery in 2005. He has papers published in international and national scientific journals, including research articles on implantology, oroantral fistulas, odontogenic cysts, and temporomandibular disorders. Dr. Emes is currently working as a full-time academic staff in Istanbul University faculty of Dentistry Department of Oral and Maxillofacial Surgery.",institutionString:null,institution:{name:"Istanbul University",country:{name:"Turkey"}}},{id:"192229",title:"Ph.D.",name:"Ana Luiza",middleName:null,surname:"De Carvalho Felippini",slug:"ana-luiza-de-carvalho-felippini",fullName:"Ana Luiza De Carvalho Felippini",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/192229/images/system/192229.jpg",biography:null,institutionString:"University of São Paulo",institution:{name:"University of Sao Paulo",country:{name:"Brazil"}}},{id:"256851",title:"Prof.",name:"Ayşe",middleName:null,surname:"Gülşen",slug:"ayse-gulsen",fullName:"Ayşe Gülşen",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/256851/images/9696_n.jpg",biography:"Dr. Ayşe Gülşen graduated in 1990 from Faculty of Dentistry, University of Ankara and did a postgraduate program at University of Gazi. \nShe worked as an observer and research assistant in Craniofacial Surgery Departments in New York, Providence Hospital in Michigan and Chang Gung Memorial Hospital in Taiwan. \nShe works as Craniofacial Orthodontist in Department of Aesthetic, Plastic and Reconstructive Surgery, Faculty of Medicine, University of Gazi, Ankara Turkey since 2004.",institutionString:"Univeristy of Gazi",institution:null},{id:"255366",title:"Prof.",name:"Tosun",middleName:null,surname:"Tosun",slug:"tosun-tosun",fullName:"Tosun Tosun",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/255366/images/7347_n.jpg",biography:"Graduated at the Faculty of Dentistry, University of Istanbul, Turkey in 1989;\nVisitor Assistant at the University of Padua, Italy and Branemark Osseointegration Center of Treviso, Italy between 1993-94;\nPhD thesis on oral implantology in University of Istanbul and was awarded the academic title “Dr.med.dent.”, 1997;\nHe was awarded the academic title “Doç.Dr.” (Associated Professor) in 2003;\nProficiency in Botulinum Toxin Applications, Reading-UK in 2009;\nMastership, RWTH Certificate in Laser Therapy in Dentistry, AALZ-Aachen University, Germany 2009-11;\nMaster of Science (MSc) in Laser Dentistry, University of Genoa, Italy 2013-14.\n\nDr.Tosun worked as Research Assistant in the Department of Oral Implantology, Faculty of Dentistry, University of Istanbul between 1990-2002. \nHe worked part-time as Consultant surgeon in Harvard Medical International Hospitals and John Hopkins Medicine, Istanbul between years 2007-09.\u2028He was contract Professor in the Department of Surgical and Diagnostic Sciences (DI.S.C.), Medical School, University of Genova, Italy between years 2011-16. \nSince 2015 he is visiting Professor at Medical School, University of Plovdiv, Bulgaria. \nCurrently he is Associated Prof.Dr. at the Dental School, Oral Surgery Dept., Istanbul Aydin University and since 2003 he works in his own private clinic in Istanbul, Turkey.\u2028\nDr.Tosun is reviewer in journal ‘Laser in Medical Sciences’, reviewer in journal ‘Folia Medica\\', a Fellow of the International Team for Implantology, Clinical Lecturer of DGZI German Association of Oral Implantology, Expert Lecturer of Laser&Health Academy, Country Representative of World Federation for Laser Dentistry, member of European Federation of Periodontology, member of Academy of Laser Dentistry. Dr.Tosun presents papers in international and national congresses and has scientific publications in international and national journals. He speaks english, spanish, italian and french.",institutionString:null,institution:{name:"Istanbul Aydın University",country:{name:"Turkey"}}},{id:"171887",title:"Prof.",name:"Zühre",middleName:null,surname:"Akarslan",slug:"zuhre-akarslan",fullName:"Zühre Akarslan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/171887/images/system/171887.jpg",biography:"Zühre Akarslan was born in 1977 in Cyprus. She graduated from Gazi University Faculty of Dentistry, Ankara, Turkey in 2000. \r\nLater she received her Ph.D. degree from the Oral Diagnosis and Radiology Department; which was recently renamed as Oral and Dentomaxillofacial Radiology, from the same university. \r\nShe is working as a full-time Associate Professor and is a lecturer and an academic researcher. \r\nHer expertise areas are dental caries, cancer, dental fear and anxiety, gag reflex in dentistry, oral medicine, and dentomaxillofacial radiology.",institutionString:"Gazi University",institution:{name:"Gazi University",country:{name:"Turkey"}}},{id:"256417",title:"Associate Prof.",name:"Sanaz",middleName:null,surname:"Sadry",slug:"sanaz-sadry",fullName:"Sanaz Sadry",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/256417/images/8106_n.jpg",biography:null,institutionString:null,institution:null},{id:"272237",title:"Dr.",name:"Pinar",middleName:"Kiymet",surname:"Karataban",slug:"pinar-karataban",fullName:"Pinar Karataban",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/272237/images/8911_n.png",biography:"Assist.Prof.Dr.Pınar Kıymet Karataban, DDS PhD \n\nDr.Pınar Kıymet Karataban was born in Istanbul in 1975. After her graduation from Marmara University Faculty of Dentistry in 1998 she started her PhD in Paediatric Dentistry focused on children with special needs; mainly children with Cerebral Palsy. She finished her pHD thesis entitled \\'Investigation of occlusion via cast analysis and evaluation of dental caries prevalance, periodontal status and muscle dysfunctions in children with cerebral palsy” in 2008. She got her Assist. Proffessor degree in Istanbul Aydın University Paediatric Dentistry Department in 2015-2018. ın 2019 she started her new career in Bahcesehir University, Istanbul as Head of Department of Pediatric Dentistry. In 2020 she was accepted to BAU International University, Batumi as Professor of Pediatric Dentistry. She’s a lecturer in the same university meanwhile working part-time in private practice in Ege Dental Studio (https://www.egedisklinigi.com/) a multidisciplinary dental clinic in Istanbul. Her main interests are paleodontology, ancient and contemporary dentistry, oral microbiology, cerebral palsy and special care dentistry. She has national and international publications, scientific reports and is a member of IAPO (International Association for Paleodontology), IADH (International Association of Disability and Oral Health) and EAPD (European Association of Pediatric Dentistry).",institutionString:null,institution:null},{id:"202198",title:"Dr.",name:"Buket",middleName:null,surname:"Aybar",slug:"buket-aybar",fullName:"Buket Aybar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/202198/images/6955_n.jpg",biography:"Buket Aybar, DDS, PhD, was born in 1971. She graduated from Istanbul University, Faculty of Dentistry, in 1992 and completed her PhD degree on Oral and Maxillofacial Surgery in Istanbul University in 1997.\nDr. Aybar is currently a full-time professor in Istanbul University, Faculty of Dentistry Department of Oral and Maxillofacial Surgery. She has teaching responsibilities in graduate and postgraduate programs. Her clinical practice includes mainly dentoalveolar surgery.\nHer topics of interest are biomaterials science and cell culture studies. She has many articles in international and national scientific journals and chapters in books; she also has participated in several scientific projects supported by Istanbul University Research fund.",institutionString:null,institution:null},{id:"260116",title:"Dr.",name:"Mehmet",middleName:null,surname:"Yaltirik",slug:"mehmet-yaltirik",fullName:"Mehmet Yaltirik",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/260116/images/7413_n.jpg",biography:"Birth Date 25.09.1965\r\nBirth Place Adana- Turkey\r\nSex Male\r\nMarrial Status Bachelor\r\nDriving License Acquired\r\nMother Tongue Turkish\r\n\r\nAddress:\r\nWork:University of Istanbul,Faculty of Dentistry, Department of Oral Surgery and Oral Medicine 34093 Capa,Istanbul- TURKIYE",institutionString:null,institution:null},{id:"172009",title:"Dr.",name:"Fatma Deniz",middleName:null,surname:"Uzuner",slug:"fatma-deniz-uzuner",fullName:"Fatma Deniz Uzuner",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/172009/images/7122_n.jpg",biography:"Dr. Deniz Uzuner was born in 1969 in Kocaeli-TURKEY. After graduating from TED Ankara College in 1986, she attended the Hacettepe University, Faculty of Dentistry in Ankara. \nIn 1993 she attended the Gazi University, Faculty of Dentistry, Department of Orthodontics for her PhD education. After finishing the PhD education, she worked as orthodontist in Ankara Dental Hospital under the Turkish Government, Ministry of Health and in a special Orthodontic Clinic till 2011. Between 2011 and 2016, Dr. Deniz Uzuner worked as a specialist in the Department of Orthodontics, Faculty of Dentistry, Gazi University in Ankara/Turkey. In 2016, she was appointed associate professor. Dr. Deniz Uzuner has authored 23 Journal Papers, 3 Book Chapters and has had 39 oral/poster presentations. She is a member of the Turkish Orthodontic Society. Her knowledge of English is at an advanced level.",institutionString:null,institution:null},{id:"332914",title:"Dr.",name:"Muhammad Saad",middleName:null,surname:"Shaikh",slug:"muhammad-saad-shaikh",fullName:"Muhammad Saad Shaikh",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Jinnah Sindh Medical University",country:{name:"Pakistan"}}},{id:"315775",title:"Dr.",name:"Feng",middleName:null,surname:"Luo",slug:"feng-luo",fullName:"Feng Luo",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Sichuan University",country:{name:"China"}}},{id:"423519",title:"Dr.",name:"Sizakele",middleName:null,surname:"Ngwenya",slug:"sizakele-ngwenya",fullName:"Sizakele Ngwenya",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of the Witwatersrand",country:{name:"South Africa"}}},{id:"419270",title:"Dr.",name:"Ann",middleName:null,surname:"Chianchitlert",slug:"ann-chianchitlert",fullName:"Ann Chianchitlert",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Walailak University",country:{name:"Thailand"}}},{id:"419271",title:"Dr.",name:"Diane",middleName:null,surname:"Selvido",slug:"diane-selvido",fullName:"Diane Selvido",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Walailak University",country:{name:"Thailand"}}},{id:"419272",title:"Dr.",name:"Irin",middleName:null,surname:"Sirisoontorn",slug:"irin-sirisoontorn",fullName:"Irin Sirisoontorn",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Walailak University",country:{name:"Thailand"}}},{id:"355660",title:"Dr.",name:"Anitha",middleName:null,surname:"Mani",slug:"anitha-mani",fullName:"Anitha Mani",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"SRM Dental College",country:{name:"India"}}},{id:"355612",title:"Dr.",name:"Janani",middleName:null,surname:"Karthikeyan",slug:"janani-karthikeyan",fullName:"Janani Karthikeyan",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"SRM Dental College",country:{name:"India"}}},{id:"334400",title:"Dr.",name:"Suvetha",middleName:null,surname:"Siva",slug:"suvetha-siva",fullName:"Suvetha Siva",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"SRM Dental College",country:{name:"India"}}}]}},subseries:{item:{id:"38",type:"subseries",title:"Pollution",keywords:"Human activity, Pollutants, Reduced risks, Population growth, Waste disposal, Remediation, Clean environment",scope:"\r\n\tPollution is caused by a wide variety of human activities and occurs in diverse forms, for example biological, chemical, et cetera. In recent years, significant efforts have been made to ensure that the environment is clean, that rigorous rules are implemented, and old laws are updated to reduce the risks towards humans and ecosystems. However, rapid industrialization and the need for more cultivable sources or habitable lands, for an increasing population, as well as fewer alternatives for waste disposal, make the pollution control tasks more challenging. Therefore, this topic will focus on assessing and managing environmental pollution. It will cover various subjects, including risk assessment due to the pollution of ecosystems, transport and fate of pollutants, restoration or remediation of polluted matrices, and efforts towards sustainable solutions to minimize environmental pollution.
",coverUrl:"https://cdn.intechopen.com/series_topics/covers/38.jpg",hasOnlineFirst:!1,hasPublishedBooks:!0,annualVolume:11966,editor:{id:"110740",title:"Dr.",name:"Ismail M.M.",middleName:null,surname:"Rahman",slug:"ismail-m.m.-rahman",fullName:"Ismail M.M. Rahman",profilePictureURL:"https://mts.intechopen.com/storage/users/110740/images/2319_n.jpg",biography:"Ismail Md. Mofizur Rahman (Ismail M. M. Rahman) assumed his current responsibilities as an Associate Professor at the Institute of Environmental Radioactivity, Fukushima University, Japan, in Oct 2015. He also has an honorary appointment to serve as a Collaborative Professor at Kanazawa University, Japan, from Mar 2015 to the present. \nFormerly, Dr. Rahman was a faculty member of the University of Chittagong, Bangladesh, affiliated with the Department of Chemistry (Oct 2002 to Mar 2012) and the Department of Applied Chemistry and Chemical Engineering (Mar 2012 to Sep 2015). Dr. Rahman was also adjunctly attached with Kanazawa University, Japan (Visiting Research Professor, Dec 2014 to Mar 2015; JSPS Postdoctoral Research Fellow, Apr 2012 to Mar 2014), and Tokyo Institute of Technology, Japan (TokyoTech-UNESCO Research Fellow, Oct 2004–Sep 2005). \nHe received his Ph.D. degree in Environmental Analytical Chemistry from Kanazawa University, Japan (2011). He also achieved a Diploma in Environment from the Tokyo Institute of Technology, Japan (2005). Besides, he has an M.Sc. degree in Applied Chemistry and a B.Sc. degree in Chemistry, all from the University of Chittagong, Bangladesh. \nDr. Rahman’s research interest includes the study of the fate and behavior of environmental pollutants in the biosphere; design of low energy and low burden environmental improvement (remediation) technology; implementation of sustainable waste management practices for treatment, handling, reuse, and ultimate residual disposition of solid wastes; nature and type of interactions in organic liquid mixtures for process engineering design applications.",institutionString:null,institution:{name:"Fukushima University",institutionURL:null,country:{name:"Japan"}}},editorTwo:{id:"201020",title:"Dr.",name:"Zinnat Ara",middleName:null,surname:"Begum",slug:"zinnat-ara-begum",fullName:"Zinnat Ara Begum",profilePictureURL:"https://mts.intechopen.com/storage/users/201020/images/system/201020.jpeg",biography:"Zinnat A. Begum received her Ph.D. in Environmental Analytical Chemistry from Kanazawa University in 2012. She achieved her Master of Science (M.Sc.) degree with a major in Applied Chemistry and a Bachelor of Science (B.Sc.) in Chemistry, all from the University of Chittagong, Bangladesh. Her work affiliations include Fukushima University, Japan (Visiting Research Fellow, Institute of Environmental Radioactivity: Mar 2016 to present), Southern University Bangladesh (Assistant Professor, Department of Civil Engineering: Jan 2015 to present), and Kanazawa University, Japan (Postdoctoral Fellow, Institute of Science and Engineering: Oct 2012 to Mar 2014; Research fellow, Venture Business Laboratory, Advanced Science and Social Co-Creation Promotion Organization: Apr 2018 to Mar 2021). The research focus of Dr. Zinnat includes the effect of the relative stability of metal-chelator complexes in the environmental remediation process designs and the development of eco-friendly soil washing techniques using biodegradable chelators.",institutionString:null,institution:{name:"Fukushima University",institutionURL:null,country:{name:"Japan"}}},editorThree:null,series:{id:"25",title:"Environmental Sciences",doi:"10.5772/intechopen.100362",issn:"2754-6713"},editorialBoard:[{id:"252368",title:"Dr.",name:"Meng-Chuan",middleName:null,surname:"Ong",slug:"meng-chuan-ong",fullName:"Meng-Chuan Ong",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRVotQAG/Profile_Picture_2022-05-20T12:04:28.jpg",institutionString:null,institution:{name:"Universiti Malaysia Terengganu",institutionURL:null,country:{name:"Malaysia"}}},{id:"63465",title:"Prof.",name:"Mohamed Nageeb",middleName:null,surname:"Rashed",slug:"mohamed-nageeb-rashed",fullName:"Mohamed Nageeb Rashed",profilePictureURL:"https://mts.intechopen.com/storage/users/63465/images/system/63465.gif",institutionString:null,institution:{name:"Aswan University",institutionURL:null,country:{name:"Egypt"}}},{id:"187907",title:"Dr.",name:"Olga",middleName:null,surname:"Anne",slug:"olga-anne",fullName:"Olga Anne",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSBE5QAO/Profile_Picture_2022-04-07T09:42:13.png",institutionString:null,institution:{name:"Klaipeda State University of Applied Sciences",institutionURL:null,country:{name:"Lithuania"}}}]},onlineFirstChapters:{paginationCount:20,paginationItems:[{id:"80964",title:"Upper Airway Expansion in Disabled Children",doi:"10.5772/intechopen.102830",signatures:"David Andrade, Joana Andrade, Maria-João Palha, Cristina Areias, Paula Macedo, Ana Norton, Miguel Palha, Lurdes Morais, Dóris Rocha Ruiz and Sônia Groisman",slug:"upper-airway-expansion-in-disabled-children",totalDownloads:35,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Oral Health Care - An Important Issue of the Modern Society",coverURL:"https://cdn.intechopen.com/books/images_new/10827.jpg",subseries:{id:"1",title:"Oral Health"}}},{id:"80839",title:"Herbs and Oral Health",doi:"10.5772/intechopen.103715",signatures:"Zuhair S. 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Thus proteomics, an area of research that detects all protein forms expressed in an organism, including splice isoforms and post-translational modifications, is more suitable than genomics for a comprehensive understanding of the biochemical processes that govern life. The most common proteomics applications are currently in the clinical field for the identification, in a variety of biological matrices, of biomarkers for diagnosis and therapeutic intervention of disorders. From the comparison of proteomic profiles of control and disease or different physiological states, which may emerge, changes in protein expression can provide new insights into the roles played by some proteins in human pathologies. Understanding how proteins function and interact with each other is another goal of proteomics that makes this approach even more intriguing. Specialized technology and expertise are required to assess the proteome of any biological sample. Currently, proteomics relies mainly on mass spectrometry (MS) combined with electrophoretic (1 or 2-DE-MS) and/or chromatographic techniques (LC-MS/MS). MS is an excellent tool that has gained popularity in proteomics because of its ability to gather a complex body of information such as cataloging protein expression, identifying protein modification sites, and defining protein interactions. 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