TY - CHAP AU - Furqan Awan AU - Muhammad Muddassir Ali AU - Muhammad Hassan Mushtaq AU - Muhammad Ijaz ED - Amjad Aqib Y1 - 2021-10-05 PY - 2021 T1 - Genetic Diversity in Staphylococcus aureus and Its Relation to Biofilm Production N2 - Staphylococcus aureus is a coccus, gram-positive, non-spore forming, and non-motile bacterium. Its commensal and opportunistic capabilities make it able to colonize different sites of animals and humans. Resistance to antibiotics has resulted in development of new strains and new types within strains. Types of methicillin-resistant S. aureus (MRSA) include hospital-acquired MRSA (HA-MRSA), community-acquired MRSA (CA-MRSA), and livestock-acquired MRSA (LA-MRSA). There are also new strains like vancomycin-resistant S. aureus (VRSA) and vancomycin-intermediate S. aureus (VISA). Expansion in resistance is expected to give rise to newer strains resistant to antibiotics such as macrolide (erm gene), tetracycline (tet genes), mupirocin (mupR), and fusidic acid (fusD). Alternative approaches like nanoparticles, bacteriophages, phytochemicals, and more are required to tackle this pathogen. This book contains information on epidemiology, resistance mechanisms, and alternative ways to curtail S. aureus infection, as well as future research opportunities. BT - Insights Into Drug Resistance in Staphylococcus aureus SP - Ch. 2 UR - https://doi.org/10.5772/intechopen.99967 DO - 10.5772/intechopen.99967 SN - 978-1-83962-743-9 PB - IntechOpen CY - Rijeka Y2 - 2024-04-25 ER -