TY - CHAP
AU - Atamjit Singh
AU - Kirandeep Kaur
AU - Pallvi Mohana
AU - Avneet Kaur
AU - Komalpreet Kaur
AU - Shilpa Heer
AU - Saroj Arora
AU - Neena Bedi
AU - Preet Mohinder Singh Bedi
ED - Amjad Aqib
Y1 - 2021-09-15
PY - 2021
T1 - Mechanistic Insights of Drug Resistance in Staphylococcus aureus with Special Reference to Newer Antibiotics
N2 - Staphylococcus aureus is a coccus, gram-positive, non-spore forming, and non-motile bacterium. Its commensal and opportunistic capabilities make it able to colonize different sites of animals and humans. Resistance to antibiotics has resulted in development of new strains and new types within strains. Types of methicillin-resistant S. aureus (MRSA) include hospital-acquired MRSA (HA-MRSA), community-acquired MRSA (CA-MRSA), and livestock-acquired MRSA (LA-MRSA). There are also new strains like vancomycin-resistant S. aureus (VRSA) and vancomycin-intermediate S. aureus (VISA). Expansion in resistance is expected to give rise to newer strains resistant to antibiotics such as macrolide (erm gene), tetracycline (tet genes), mupirocin (mupR), and fusidic acid (fusD). Alternative approaches like nanoparticles, bacteriophages, phytochemicals, and more are required to tackle this pathogen. This book contains information on epidemiology, resistance mechanisms, and alternative ways to curtail S. aureus infection, as well as future research opportunities.
BT - Insights Into Drug Resistance in Staphylococcus aureus
SP - Ch. 4
UR - https://doi.org/10.5772/intechopen.100045
DO - 10.5772/intechopen.100045
SN - 978-1-83962-743-9
PB - IntechOpen
CY - Rijeka
Y2 - 2024-04-23
ER -