TY  - CHAP
AU  - Irina Vlasova-St. Louis
AU  - Andrew Gorzalski
AU  - Mark Pandori
ED  - Irina Vlasova-St. Louis
Y1  - 2021-07-29
PY  - 2021
T1  - Diagnostic Applications for RNA-Seq Technology and Transcriptome Analyses in Human Diseases Caused by RNA Viruses
N2  - This book evaluates and comprehensively summarizes the scientific findings that have been achieved through RNA-sequencing (RNA-Seq) technology. RNA-Seq transcriptome profiling of healthy and diseased tissues allows FOR understanding the alterations in cellular phenotypes through the expression of differentially spliced RNA isoforms. Assessment of gene expression by RNA-Seq provides new insight into host response to pathogens, drugs, allergens, and other environmental triggers. RNA-Seq allows us to accurately capture all subtypes of RNA molecules, in any sequenced organism or single-cell type, under different experimental conditions. Merging genomics and transcriptomic profiling provides novel information underlying causative DNA mutations. Combining RNA-Seq with immunoprecipitation and cross-linking techniques is a clever multi-omics strategy assessing transcriptional, post-transcriptional and post-translational levels of gene expression regulation.
BT  - Applications of RNA-Seq in Biology and Medicine
SP  - Ch. 5
UR  - https://doi.org/10.5772/intechopen.99156
DO  - 10.5772/intechopen.99156
SN  - 978-1-83962-815-3
PB  - IntechOpen
CY  - Rijeka
Y2  - 2024-04-23
ER  -