TY - CHAP AU - Luiza Rusu ED - Imtiaz A. Chaudhry Y1 - 2021-05-20 PY - 2021 T1 - Cellular and Molecular Characteristics of Vascular Damage in Giant Cell Arteritis, the ‘Unmet Needs’ for Targeted Treatment N2 - Giant cell arteritis (GCA) is a systemic vasculitis that affects medium- to large-size arteries in which an inflammatory reaction destroys the media of the artery wall with the fragmentation of the elastic lamina, which can result in acute vision loss if not treated in a timely manner. The other common visual symptoms may include diplopia due to cranial nerve palsies and transient visual loss. This book provides a comprehensive overview of GCA, with chapters on epidemiology, cellular and molecular characteristics of the disease, extra-cranial involvement of GCA, medical imaging, and much more. BT - Giant-Cell Arteritis SP - Ch. 2 UR - https://doi.org/10.5772/intechopen.97933 DO - 10.5772/intechopen.97933 SN - 978-1-83969-209-3 PB - IntechOpen CY - Rijeka Y2 - 2024-04-27 ER -