TY - CHAP AU - Gianfranco Lapietra AU - Francesca Fazio AU - Maria Teresa Petrucci ED - Ota Fuchs Y1 - 2021-02-10 PY - 2021 T1 - The Modern Age of Monoclonal Antibodies: The Revolution of Daratumumab N2 - This book deals with the diagnosis and treatment of multiple myeloma. Multiple myeloma is a plasma cell disorder, the prognosis of which has dramatically improved in the last years thanks to new immunomodulatory drugs, proteasome inhibitors, and monoclonal antibodies, in relapsed/refractory disease and a diagnosis. Chapters cover such topics as prognostic and predictive factors in newly diagnosed multiple myeloma, treatment approaches, antibody therapies, and three-dimensional (3D) models mimicking multiple myeloma bone marrow–microenvironment interactions. BT - Multiple Myeloma SP - Ch. 5 UR - https://doi.org/10.5772/intechopen.95406 DO - 10.5772/intechopen.95406 SN - 978-1-83968-621-4 PB - IntechOpen CY - Rijeka Y2 - 2024-04-19 ER -