TY - CHAP AU - Henry Puerta-Guardo AU - Scott B. Biering AU - Eva Harris AU - Norma Pavia-Ruz AU - Gonzalo Vázquez-Prokopec AU - Guadalupe Ayora-Talavera AU - Pablo Manrique-Saide ED - Márcia Aparecida Sperança Y1 - 2020-09-23 PY - 2020 T1 - Dengue Immunopathogenesis: A Crosstalk between Host and Viral Factors Leading to Disease: PART II - DENV Infection, Adaptive Immune Responses, and NS1 Pathogenesis N2 - Dengue Fever in a One Health Perspective underlines important aspects of dengue virus, the most prevalent and life-threatening arbovirus in the world. Over three sections, chapters cover such topics as biological and environmental aspects, physiopathology, molecular biology, diagnosis, and control strategies. The first section provides knowledge on basic aspects of dengue virus biology and its emergence and re-emergence associated to environmental changes. The second section includes two chapters on dengue immunopathology, a drawback in disease control and vaccine development. Finally, the third section examines molecular biology tools employed in dengue virus immunopathogenesis studies, diagnosis, drug design, and in the use of vectors as sentinels in surveillance and vector biology studies. BT - Dengue Fever in a One Health Perspective SP - Ch. 5 UR - https://doi.org/10.5772/intechopen.93551 DO - 10.5772/intechopen.93551 SN - 978-1-78985-649-1 PB - IntechOpen CY - Rijeka Y2 - 2024-04-26 ER -