TY - CHAP AU - John W. Cassidy ED - John W. Cassidy ED - Belle Taylor Y1 - 2020-09-09 PY - 2020 T1 - Applications of Machine Learning in Drug Discovery II: Biomarker Discovery, Patient Stratification and Pharmacoeconomics N2 - There exists a profound conflict at the heart of oncology drug development. The efficiency of the drug development process is falling, leading to higher costs per approved drug, at the same time personalised medicine is limiting the target market of each new medicine. Even as the global economic burden of cancer increases, the current paradigm in drug development is unsustainable. In this book, we discuss the development of techniques in machine learning for improving the efficiency of oncology drug development and delivering cost-effective precision treatment. We consider how to structure data for drug repurposing and target identification, how to improve clinical trials and how patients may view artificial intelligence. BT - Artificial Intelligence in Oncology Drug Discovery and Development SP - Ch. 5 UR - https://doi.org/10.5772/intechopen.93160 DO - 10.5772/intechopen.93160 SN - 978-1-78985-897-6 PB - IntechOpen CY - Rijeka Y2 - 2024-04-25 ER -