TY  - CHAP
AU  - Reinhold P. Linke
ED  - Vincenzo Neri
Y1  - 2020-07-07
PY  - 2020
T1  - The Invariant Peptide Clusters of Serum Amyloid A Are Humoral Checkpoints for Vital Innate Functions as Probed by Monoclonal Antibodies, Including in Sepsis: Induction by Febrile Temperatures and Path of Discoveries
N2  - Sepsis is a very complex clinical condition that can be considered the central point of the infectious process: the arrival point in the evolution of a localized septic outbreak that has caused a systemic inflammatory reaction. In the clinical setting two important questions regarding the transition from local inflammation, with beneficial effect, to systemic inflammatory disease, with deleterious results, remain unanswered. First, why does the transition from local to systemic disease only occur in some subjects? Second, how long does this transition take? This book attempts to answer these questions. Chapters cover such topics as surgical infections, microbiota therapy in sepsis, cytokines for host immune response, and the role of serum amyloid A in the acute phase of sepsis.
BT  - Infectious Process and Sepsis
SP  - Ch. 6
UR  - https://doi.org/10.5772/intechopen.91983
DO  - 10.5772/intechopen.91983
SN  - 978-1-83880-394-0
PB  - IntechOpen
CY  - Rijeka
Y2  - 2024-04-26
ER  -