TY - CHAP AU - Ota Fuchs ED - Ota Fuchs ED - Seyyed Shamsadin Athari Y1 - 2020-05-13 PY - 2020 T1 - Introductory Chapter: Development of Neutrophils and Their Role in Hematopoietic Microenvironment Regulation N2 - The cells of the immune system are lymphocytes (T-cells, B-cells and NK (natural killer) cells), neutrophils, eosinophils, and monocytes/macrophages. This book is an overview of some types of these cells and their role in recognizing and/or reacting against foreign material. The immune system is characterized by collaboration between cells and proteins. The development of all cells of the immune system begins in the bone marrow with a hematopoietic stem cell. Two chapters deal with neutrophils, three chapters with T-cells, four chapters with eosinophils, and other chapters review the immunomodulation of macrophages, the role of transcription factor KLF4 in regulating plasticity of myeloid-derived suppressor cells, immune reconstitution after allogeneic hematopoietic stem cell transplantation, and role of sorption detoxification in the therapy of acute radiation sickness. BT - Cells of the Immune System SP - Ch. 1 UR - https://doi.org/10.5772/intechopen.91269 DO - 10.5772/intechopen.91269 SN - 978-1-78985-584-5 PB - IntechOpen CY - Rijeka Y2 - 2024-03-29 ER -