TY - CHAP AU - Partha Karmakar AU - Ashit Trivedi AU - Vishwanath Gaitonde ED - Vishwanath Gaitonde ED - Partha Karmakar ED - Ashit Trivedi Y1 - 2020-03-11 PY - 2020 T1 - Introductory Chapter: The Modern-Day Drug Discovery N2 - The process of drug discovery and development is a complex multistage logistics project spanned over 10-15 years with an average budget exceeding 1 billion USD. Starting with target identification and synthesizing anywhere between 10k to 15k synthetic compounds to potentially obtain the final drug that reaches the market involves a complicated maze with multiple inter- and intra-operative fields. Topics described in this book emphasize the progresses in computational applications, pharmacokinetics advances, and molecular modeling developments. In addition the book also contains special topics describing target deorphaning in Mycobacterium tuberculosis, therapy treatment of some rare diseases, and developments in the pediatric drug discovery process. BT - Drug Discovery and Development SP - Ch. 1 UR - https://doi.org/10.5772/intechopen.90922 DO - 10.5772/intechopen.90922 SN - 978-1-78923-976-8 PB - IntechOpen CY - Rijeka Y2 - 2024-04-19 ER -