TY - CHAP AU - Amene Saghazadeh AU - Nima Rezaei ED - Nima Rezaei Y1 - 2020-01-29 PY - 2020 T1 - Introductory Chapter: Thymus - The Central Self-Tolerance System N2 - The thymus gland is highly valuable, due to its functions as a part of the neuroendocrine system as well as its actions to provide a primary lymphoid microenvironment that efficiently carries T-cell differentiation and selection. This book begins with an introduction and explanation of the development of the thymus. Subsequent chapters examine a range of conditions - including environmental pollution, congenital anomalies, autoimmune diseases, and malignancies - that threaten the function and development of the thymus. The information presented herein is useful for a wide range of readers across a variety of specialties. BT - Thymus SP - Ch. 1 UR - https://doi.org/10.5772/intechopen.90491 DO - 10.5772/intechopen.90491 SN - 978-1-78985-134-2 PB - IntechOpen CY - Rijeka Y2 - 2024-04-25 ER -